Yoo Jin Lee, MD

Title(s)Assistant Professor, Radiology
SchoolSchool of Medicine
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    Collapse Education and Training
    University of Virginia, Charlottesville, VAClinical Fellowship2020Nuclear Medicine
    University of Virginia, Charlottesville, VAClinical Instructor2019Nuclear Medicine
    University of Virginia, Charlottesville, VAClinical Fellowship2018Cardiothoracic Radiology
    University of Virginia, Charlottesville, VAResearch Associate2017Cardiovascular Radiology
    Kyunpook National University, South KoreaInternship2008Medicine
    Kyungpook National University, South KoreaMD2007Medicine

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    Collapse Overview
    Yoo Jin Lee, MD earned her medical degree at Kyungpook National University, followed by an internship and diagnostic radiology residency at the same institution. Dr. Lee was a research associate in Cardiovascular Radiology, and a clinical instructor and clinical fellow in Nuclear Medicine at the University of Virginia in Charlottesville.

    Dr. Lee's clinical work focuses on thoracic, cardiac, and noninvasive vascular imaging for endovascular intervention and cardiovascular surgery and vascular disease.

    Her major research focuses on Cardiothoracic MRI imaging, which includes parametric mapping, myocardial scar imaging using 3D late gadolinium enhancement (LGE), thoracic MRI using 0.55T MRI, and pulmonary vascular MRI imaging.

    Multimodality imaging of cardiac fibrosis is another direction of research of Dr Lee specifically Cardiac PET/CT and PET/MR using novel radiotracer in comparison to parametric mapping and LGE sequences from Cardiac MRI.

    Collapse Research 
    Collapse Research Activities and Funding
    Preliminary cardiac imaging at high-performance 0.55T MRI
    Siemens Siemens Seed GrantNov 15, 2022 - Nov 14, 2023
    Role: Co-Investigator
    Description: This grant program is intended to support the initial stage of new research directions on the Siemens scanners at China Basin in preparation for attracting additional multiyear funding from extramural sources.
    Preliminary cardiac imaging at high-performance 0.55T MRI
    Siemens Siemens Seed GrantNov 15, 2022 - Nov 14, 2023
    Role: Primary Investigator
    Description: This grant program is intended to support the initial stage of new research directions on the Siemens scanners at China Basin in preparation for attracting additional multiyear funding from extramural sources.
    Efficient and Comprehensive Advanced Magnetic Resonance Imaging of Hereditary Hemorrhagic Telangiectasia Vascular Malformations (AVIATOR)
    NIH/CSR W81XWH2210178 (A139676)Aug 1, 2022 - Jul 1, 2026
    Role: Co-Investigator
    Description: Major Goals: The major goals of this project are to propose a paradigm shift in the evaluation of vascular malformations, a specific area of encouragement for the Investigator-Initiated Research Award. Patients with hereditary hemorrhagic telangiectasia (HHT), a genetic condition causing a high frequency of arteriovenous malformations (AVMs) in the brain, lung, and liver, will benefit from the development of an efficient MRI screening protocol for those organs to replace multiple types of MRI, CT, and ultrasound examinations currently used for screening. Additional development of targeted MR imaging techniques at 3T and 7T will better define the anatomic and physiologic features of multiorgan AVMs that stratify lesion risk, guide treatment decisions, monitor responses to therapy, and will save costs as compared to current methods that employ invasive catheter angiography.
    Imaging of Active Myocardial Fibrosis Using 68Ga-FAP-2286
    Radiological Society of North America (RSNA) RSNA Research Scholar grantJul 1, 2022 - Jun 30, 2024
    Role: Primary Investigator
    Description: The overall goal of this project is to evaluate the ability of a novel imaging agent (68Ga-fibroblast activation protein (FAP)-2286) to detect active pathologic myocardial fibrosis.
    Improved Cardiac MRI: Fast, Free-Breathing, Quantitative, Without Contrast Administration.
    Huntington Memorial Fund REAC AWARDJan 1, 2022 - Dec 31, 2022
    Role: Co-Investigator
    Description: Fast, Free-Breathing, Quantitative, Without Contrast Administration through parametric methods.
    SPIROMICS II: Heart Failure
    NIH R01 HL093081Sep 20, 2019 - Jun 30, 2024
    Role: Co-Investigator
    Description: The overall objective of the SPIROMICS HF study is to examine heart-lung interactions to suggest new diagnostic and therapeutic strategies for COPD and HF. The study will examine specific cardiopulmonary pathophysiological abnormalities in a variety of COPD subtypes, with echocardiography as a key component in determining the cardiac pathophysiology that is unique to each COPD subtype. The other major components include a cardiopulmonary MRI and cardiac risk factors.
    Novel Arrhythmic Risk Screening Using Cardiac MRI and ECG Machine Learning in Mitral Valve Prolapse
    UCSF, Cardiology Cardiology Innovation Award 7027291Jul 1, 2019 - Jun 30, 2022
    Role: Co-Investigator
    Description: These internal funds are supporting the creation of an MVP registry of consecutive MVP patients with ECGs, contrast-enhanced CMR and Holter monitors with the goal of developing ECG-based machine learning tools to detect arrhythmic MVP and its myocardial substrates.
    Evaluation of HIV- associated Cardiac Dysfunction in Women
    NIH R01HL132794Jul 1, 2019 - Mar 31, 2021
    Role: Co-Investigator
    Description: Evaluation of HIV- associated Cardiac Dysfunction in Women Using repeated measures of HIV-specific exposures and ART, and added biomarkers of cardiac stress, inflammation and lipid dysregulation, this proposal stands to provide important new knowledge concerning the role of HIV infection and related factors in subclinical myocardial dysfunction and disease. In so doing, the proposed project will identify strategies and future research to avert the potential rise in symptomatic HF that threatens the HIV-infected population in the cART era.
    Effect of PCSK9 Inhibition on Cardiovascular Risk in Treated HIV Infection (EPIC-HIV Study)
    NIH R33HL141047Feb 1, 2019 - Jan 31, 2023
    Role: Co-Investigator
    Description: This is a double-blind, placebo-controlled trial to assess the effect of marked LDL lowering using PCSK9 inhibition on atherosclerosis in HIV. This project evaluates the impact of PCSK9 antagonism on 3 imaging indices that are known to be abnormal in HIV: 1) arterial inflammation using FDG-PET/CT, 2) endothelial function, and 3) non-calcified plaque by CT angiography.

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