Afsaneh Amouzegar • UCSF Profiles

Afsaneh Amouzegar, MD

Title(s)	Assistant Professor, Medicine
School	School of Medicine
Address	1825 4th Street, #L3101 San Francisco CA 94158
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Biography

education and training

Tehran University of Medical Sciences, Tehran, Iran	MD	2014	Medicine
Schepens Research Institute, Harvard Medical School, Boston, MA	Postdoctoral Research Fellowship	2019	Immunology
University of Pittsburgh Medical Center, Pittsburgh, PA	Residency	2022	Internal Medicine
University of Texas MD Anderson Cancer Center, Houston, TX	Fellowship	2025	Hematology/Oncology

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Treatment of hypothyroidism with levothyroxine plus slow-release liothyronine: a study protocol for a randomized controlled double-blinded clinical trial. Trials. 2025 Jul 01; 26(1):228. Azizi F, Amouzegar A, Abdi H, Tohidi M, Masoumi S, Khalili D, Mehrabi Y, Zadehvakili A, Hedayati M, Momenan AA, Mehran L. PMID: 40598574; PMCID: PMC12211365.

View in: PubMed Mentions:
Treatment of hypothyroidism with the combination of levothyroxine and slow-release triiodothyronine: a randomized clinical trial. J Clin Transl Endocrinol. 2025 Jun; 40:100395. Azizi F, Moeini AS, Mehran L, Masoumi S, Abdi H, Foroutan SM, Saghafinia AE, Amouzegar A. PMID: 40453773; PMCID: PMC12123354.

View in: PubMed Mentions:
Radiomic analysis of patient and interorgan heterogeneity in response to immunotherapies and BRAF-targeted therapy in metastatic melanoma. J Immunother Cancer. 2025 Feb 12; 13(2). Tompkins AG, Gray ZN, Dadey RE, Zenkin S, Batavani N, Newman S, Amouzegar A, Ak M, Ak N, Pak TY, Peddagangireddy V, Mamindla P, Amjadzadeh M, Behr S, Goodman A, Ploucha DL, Kirkwood JM, Zarour HM, Najjar YG, Davar D, Tatsuoka C, Colen RR, Luke JJ, Bao R. PMID: 39939139; PMCID: PMC11822426.

View in: PubMed Mentions: 1 Fields:
Neo Neoplasms The Therapeutics
Translation:Humans
Navigating the Complexities of Brain Metastases Management. Am Soc Clin Oncol Educ Book. 2024 Jun; 44(3):e433694. Amouzegar A, Haig S, Kahn AM, Tawbi HA, Jones JA, Goldberg SB. PMID: 38781565.

View in: PubMed Mentions: 4 Fields:
Neo Neoplasms
Translation:Humans
Radiomic analysis of patient and inter-organ heterogeneity in response to immunotherapies and BRAF targeted therapy in metastatic melanoma. medRxiv. 2024 Apr 27. Tompkins A, Gray ZN, Dadey RE, Zenkin S, Batavani N, Newman S, Amouzegar A, Ak M, Ak N, Pak TY, Peddagangireddy V, Mamindla P, Behr S, Goodman A, Ploucha DL, Kirkwood JM, Zarour HM, Najjar YG, Davar D, Colen R, Luke JJ, Bao R. PMID: 38712112; PMCID: PMC11071587.

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Local and Systemic Management Options for Melanoma Brain Metastases. Cancer J. 2024 Mar-Apr 01; 30(2):102-107. Amouzegar A, Tawbi HA. PMID: 38527263.

View in: PubMed Mentions: Fields:
Neo Neoplasms
Translation:Humans
Amplified Natural Killer Cell Activity and Attenuated Regulatory T-cell Function Are Determinants for Corneal Alloimmunity in Very Young Mice. Transplantation. 2023 06 01; 107(6):1302-1310. Nakao T, Inomata T, Blanco T, Musayeva A, Tahvildari M, Amouzegar A, Yin J, Chauhan SK, Chen Y, Dana R. PMID: 36584368; PMCID: PMC10205651.

View in: PubMed Mentions: 2 Fields:
Tra Transplantation
Translation:Animals Cells
Natural history of subclinical hypothyroidism and prognostic factors for the development of overt hypothyroidism: Tehran Thyroid Study (TTS). J Endocrinol Invest. 2022 Dec; 45(12):2353-2364. Amouzegar A, Dehghani M, Abdi H, Mehran L, Masoumi S, Azizi F. PMID: 35925467.

View in: PubMed Mentions:
Weight fluctuation, mortality, and cardiovascular disease in adults in 18 years of follow-up: Tehran Lipid and Glucose Study. J Endocrinol Invest. 2023 Jan; 46(1):37-49. Mehran L, Honarvar M, Masoumi S, Khalili D, Amouzegar A, Azizi F. PMID: 35921037.

View in: PubMed Mentions:
Treatment of post-radioactive iodine relapse of hyperthyroidism: comparison of long-term methimazole and radioactive iodine treatment. J Endocrinol Invest. 2022 Oct; 45(10):1919-1924. Saadat N, Azizi F, Abdi H, Amouzegar A. PMID: 35610532.

View in: PubMed Mentions:
Appropriate duration of antithyroid drug treatment as a predictor for relapse of Graves' disease: a systematic scoping review. J Endocrinol Invest. 2022 Jun; 45(6):1139-1150. Azizi F, Abdi H, Mehran L, Amouzegar A. PMID: 35088381.

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TPO antibody in euthyroid pregnant women and cognitive ability in the offspring: a focused review. J Endocrinol Invest. 2022 Feb; 45(2):425-431. Amouzegar A, Pearce EN, Mehran L, Lazarus J, Takyar M, Azizi F. PMID: 34515961.

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Next-Generation Immunotherapy Approaches in Melanoma. Curr Oncol Rep. 2021 08 03; 23(10):116. Buchanan T, Amouzegar A, Luke JJ. PMID: 34342752; PMCID: PMC11552657.

View in: PubMed Mentions: 2 Fields:
Neo Neoplasms
Translation:Humans Cells
STING Agonists as Cancer Therapeutics. Cancers (Basel). 2021 May 30; 13(11). Amouzegar A, Chelvanambi M, Filderman JN, Storkus WJ, Luke JJ. PMID: 34070756; PMCID: PMC8198217.

View in: PubMed Mentions: 198
Restoration of Regulatory T-Cell Function in Dry Eye Disease by Antagonizing Substance P/Neurokinin-1 Receptor. Am J Pathol. 2020 09; 190(9):1859-1866. Taketani Y, Marmalidou A, Dohlman TH, Singh RB, Amouzegar A, Chauhan SK, Chen Y, Dana R. PMID: 32473919; PMCID: PMC7456741.

View in: PubMed Mentions: 21 Fields:
Pat Pathology
Translation:Animals Cells
The functions of IL-23 and IL-2 on driving autoimmune effector T-helper 17 cells into the memory pool in dry eye disease. Mucosal Immunol. 2021 01; 14(1):177-186. Chen Y, Shao C, Fan NW, Nakao T, Amouzegar A, Chauhan SK, Dana R. PMID: 32327706; PMCID: PMC7581618.

View in: PubMed Mentions: 15 Fields:
All Allergy and Immunology
Translation:Humans Animals Cells
Regulatory T cells promote corneal endothelial cell survival following transplantation via interleukin-10. Am J Transplant. 2020 02; 20(2):389-398. Coco G, Foulsham W, Nakao T, Yin J, Amouzegar A, Taketani Y, Chauhan SK, Dana R. PMID: 31587452; PMCID: PMC6984989.

View in: PubMed Mentions: 9 Fields:
Tra Transplantation
Translation:Animals Cells
Neurokinin-1 Receptor Antagonism Ameliorates Dry Eye Disease by Inhibiting Antigen-Presenting Cell Maturation and T Helper 17 Cell Activation. Am J Pathol. 2020 01; 190(1):125-133. Yu M, Lee SM, Lee H, Amouzegar A, Nakao T, Chen Y, Dana R. PMID: 31669306; PMCID: PMC6943374.

View in: PubMed Mentions: 27 Fields:
Pat Pathology
Translation:Animals Cells
The therapeutic application of mesenchymal stem cells at the ocular surface. Ocul Surf. 2019 04; 17(2):198-207. Sahu A, Foulsham W, Amouzegar A, Mittal SK, Chauhan SK. PMID: 30695735; PMCID: PMC7931249.

View in: PubMed Mentions: 20 Fields:
Oph Ophthalmology
Translation:Humans Animals Cells
Local Delivery of Regulatory T Cells Promotes Corneal Allograft Survival. Transplantation. 2019 01; 103(1):182-190. Shao C, Chen Y, Nakao T, Amouzegar A, Yin J, Tahvildari M, Lužnik Z, Chauhan SK, Dana R. PMID: 30247445; PMCID: PMC6309927.

View in: PubMed Mentions: 17 Fields:
Tra Transplantation
Translation:Animals Cells
Peripheral Blood or Bone Marrow Stem Cells? Practical Considerations in Hematopoietic Stem Cell Transplantation. Transfus Med Rev. 2019 01; 33(1):43-50. Amouzegar A, Dey BR, Spitzer TR. PMID: 30528986.

View in: PubMed Mentions: 26 Fields:
Hem Hematology
Translation:Humans Cells
Regulatory T cell modulation of cytokine and cellular networks in corneal graft rejection. Curr Ophthalmol Rep. 2018 Dec; 6(4):266-274. Tahvildari M, Inomata T, Amouzegar A, Dana R. PMID: 31807370; PMCID: PMC6894425.

View in: PubMed Mentions: 13
Mast cells contribute to the induction of ocular mucosal alloimmunity. Am J Transplant. 2019 03; 19(3):662-673. Li M, Mittal SK, Foulsham W, Amouzegar A, Sahu SK, Chauhan SK. PMID: 30129280; PMCID: PMC7941346.

View in: PubMed Mentions: 13 Fields:
Tra Transplantation
Translation:Animals Cells PHPublic Health
Vasoactive Intestinal Peptide Promotes Corneal Allograft Survival. Am J Pathol. 2018 09; 188(9):2016-2024. Satitpitakul V, Sun Z, Suri K, Amouzegar A, Katikireddy KR, Jurkunas UV, Kheirkhah A, Dana R. PMID: 30097165; PMCID: PMC6593256.

View in: PubMed Mentions: 15 Fields:
Pat Pathology
Translation:Humans Animals Cells
The immunoregulatory role of corneal epithelium-derived thrombospondin-1 in dry eye disease. Ocul Surf. 2018 10; 16(4):470-477. Tan X, Chen Y, Foulsham W, Amouzegar A, Inomata T, Liu Y, Chauhan SK, Dana R. PMID: 30055331; PMCID: PMC6289260.

View in: PubMed Mentions: 21 Fields:
Oph Ophthalmology
Translation:Humans Animals Cells
Mesenchymal Stromal Cells Inhibit Neutrophil Effector Functions in a Murine Model of Ocular Inflammation. Invest Ophthalmol Vis Sci. 2018 03 01; 59(3):1191-1198. Mittal SK, Mashaghi A, Amouzegar A, Li M, Foulsham W, Sahu SK, Chauhan SK. PMID: 29625439; PMCID: PMC5837663.

View in: PubMed Mentions: 18 Fields:
Oph Ophthalmology
Translation:Animals Cells
Therapeutic approaches for induction of tolerance and immune quiescence in corneal allotransplantation. Cell Mol Life Sci. 2018 05; 75(9):1509-1520. Tahvildari M, Amouzegar A, Foulsham W, Dana R. PMID: 29307015; PMCID: PMC5899040.

View in: PubMed Mentions: 9 Fields:
Cel Cell Biology Mol Molecular Biology
Translation:Humans Animals Cells
Interleukin-6 neutralization prolongs corneal allograft survival. Curr Trends Immunol. 2018; 19:105-113. Kodati S, Chauhan SK, Chen Y, Emami-Naeini P, Omoto M, Dohlman TH, Stevenson W, Amouzegar A, Tummala G, Saban DR, Dana R. PMID: 30906117; PMCID: PMC6428205.

View in: PubMed Mentions: 6
Corneal Tissue From Dry Eye Donors Leads to Enhanced Graft Rejection. Cornea. 2018 Jan; 37(1):95-101. Inomata T, Hua J, Nakao T, Shiang T, Chiang H, Amouzegar A, Dana R. PMID: 29023237; PMCID: PMC5716893.

View in: PubMed Mentions: 16 Fields:
Oph Ophthalmology
Translation:Humans Animals Cells
When Clarity Is Crucial: Regulating Ocular Surface Immunity. Trends Immunol. 2018 04; 39(4):288-301. Foulsham W, Coco G, Amouzegar A, Chauhan SK, Dana R. PMID: 29248310; PMCID: PMC5880704.

View in: PubMed Mentions: 40 Fields:
All Allergy and Immunology
Translation:Humans Animals
Thyroid dysfunction in patients with impaired glucose metabolism: 11 year follow up from the Tehran Thyroid Study. PLoS One. 2017; 12(10):e0184808. Gholampour Dehaki M, Amouzegar A, Delshad H, Mehrabi Y, Tohidi M, Azizi F. PMID: 28972979; PMCID: PMC5626423.

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Kinetics of Corneal Antigen Presenting Cells in Experimental Dry Eye Disease. BMJ Open Ophthalmol. 2017; 1(1):e000078. Lee HS, Amouzegar A, Dana R. PMID: 29354712; PMCID: PMC5721641.

View in: PubMed Mentions: 24 Fields:
Oph Ophthalmology
Review: The function of regulatory T cells at the ocular surface. Ocul Surf. 2017 10; 15(4):652-659. Foulsham W, Marmalidou A, Amouzegar A, Coco G, Chen Y, Dana R. PMID: 28576753; PMCID: PMC5623071.

View in: PubMed Mentions: 23 Fields:
Oph Ophthalmology
Translation:Humans Cells
Hepatocyte Growth Factor Suppresses Inflammation and Promotes Epithelium Repair in Corneal Injury. Mol Ther. 2017 08 02; 25(8):1881-1888. Omoto M, Suri K, Amouzegar A, Li M, Katikireddy KR, Mittal SK, Chauhan SK. PMID: 28502469; PMCID: PMC5542635.

View in: PubMed Mentions: 46 Fields:
Mol Molecular Biology The Therapeutics
Translation:Humans Animals Cells
Effector and Regulatory T Cell Trafficking in Corneal Allograft Rejection. Mediators Inflamm. 2017; 2017:8670280. Amouzegar A, Chauhan SK. PMID: 28539707; PMCID: PMC5429952.

View in: PubMed Mentions: 13 Fields:
Bio Biochemistry Pat Pathology
Translation:Humans Animals Cells
Mesenchymal Stem Cells Modulate Differentiation of Myeloid Progenitor Cells During Inflammation. Stem Cells. 2017 06; 35(6):1532-1541. Amouzegar A, Mittal SK, Sahu A, Sahu SK, Chauhan SK. PMID: 28295880; PMCID: PMC5446294.

View in: PubMed Mentions: 21 Fields:
Cel Cell Biology Emb Embryology
Translation:Animals Cells
Restoration of Corneal Transparency by Mesenchymal Stem Cells. Stem Cell Reports. 2016 10 11; 7(4):583-590. Mittal SK, Omoto M, Amouzegar A, Sahu A, Rezazadeh A, Katikireddy KR, Shah DI, Sahu SK, Chauhan SK. PMID: 27693426; PMCID: PMC5063582.

View in: PubMed Mentions: 63 Fields:
Cel Cell Biology
Translation:Humans Animals Cells
Alloimmunity and Tolerance in Corneal Transplantation. J Immunol. 2016 05 15; 196(10):3983-91. Amouzegar A, Chauhan SK, Dana R. PMID: 27183635; PMCID: PMC4874505.

View in: PubMed Mentions: 75 Fields:
All Allergy and Immunology
Translation:Humans Animals
The Association Between Blood Pressure and Normal Range Thyroid Function Tests in a Population Based Tehran Thyroid Study. Horm Metab Res. 2016 Mar; 48(3):151-156. Amouzegar A, Heidari M, Gharibzadeh S, Mehran L, Tohidi M, Azizi F. PMID: 26671752.

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Correlation of major components of ocular astigmatism in myopic patients. Cont Lens Anterior Eye. 2016 Feb; 39(1):20-5. Mohammadpour M, Heidari Z, Khabazkhoob M, Amouzegar A, Hashemi H. PMID: 26187142.

View in: PubMed Mentions: 12 Fields:
Oph Ophthalmology
Translation:Humans
Association between thyroid hormones, thyroid antibodies and insulin resistance in euthyroid individuals: A population-based cohort. Diabetes Metab. 2015 Dec; 41(6):480-8. Amouzegar A, Kazemian E, Gharibzadeh S, Mehran L, Tohidi M, Azizi F. PMID: 26049821.

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Comparison of Lotrafilcon B and Balafilcon A silicone hydrogel bandage contact lenses in reducing pain and discomfort after photorefractive keratectomy: A contralateral eye study. Cont Lens Anterior Eye. 2015 Jun; 38(3):211-4. Mohammadpour M, Amouzegar A, Hashemi H, Jabbarvand M, Kordbacheh H, Rahimi F, Hashemian MN. PMID: 25843674.

View in: PubMed Mentions: 9 Fields:
Oph Ophthalmology
Translation:Humans
Prevalence of hypothyroidism in patients with dyslipidemia: Tehran Thyroid Study (TTS). Horm Metab Res. 2014 Dec; 46(13):980-4. Khazan M, Amouzegar A, Gharibzadeh S, Mehran L, Tohidi M, Azizi F. PMID: 25369072.

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Underestimation of thyroid dysfunction risk due to regression dilution bias in a long-term follow-up: Tehran Thyroid Study (TTS). Horm Metab Res. 2014 Jun; 46(6):440-4. Amouzegar A, Beigy M, Gharibzadeh S, Azizi F. PMID: 24799022.

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Local versus international recommended TSH references in the assessment of thyroid function during pregnancy. Horm Metab Res. 2014 Mar; 46(3):206-10. Amouzegar A, Ainy E, Khazan M, Mehran L, Hedayati M, Azizi F. PMID: 24505029.

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An assessment of the iodine status and the correlation between iodine nutrition and thyroid function during pregnancy in an iodine sufficient area. Eur J Clin Nutr. 2014 Mar; 68(3):397-400. Amouzegar A, Khazan M, Hedayati M, Azizi F. PMID: 24398634.

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Reference limit of thyrotropin (TSH) and free thyroxine (FT4) in thyroperoxidase positive and negative subjects: a population based study. J Endocrinol Invest. 2013 Dec; 36(11):950-4. Amouzegar A, Delshad H, Mehran L, Tohidi M, Khafaji F, Azizi F. PMID: 23873252.

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5-HT(3) receptor mediates the dose-dependent effects of citalopram on pentylenetetrazole-induced clonic seizure in mice: involvement of nitric oxide. Epilepsy Res. 2012 Sep; 101(3):217-27. Payandemehr B, Bahremand A, Rahimian R, Ziai P, Amouzegar A, Sharifzadeh M, Dehpour AR. PMID: 22578701.

View in: PubMed Mentions: 13 Fields:
Bra Brain Neu Neurology
Translation:Animals
Additive anticonvulsant effects of agmatine and lithium chloride on pentylenetetrazole-induced clonic seizure in mice: involvement of α₂-adrenoceptor. Eur J Pharmacol. 2011 Sep; 666(1-3):93-9. Bahremand A, Ziai P, Payandemehr B, Rahimian R, Amouzegar A, Khezrian M, Montaser-Kouhsari L, Meibodi MA, Ebrahimi A, Ghasemi A, Ghasemi M, Dehpour AR. PMID: 21651904.

View in: PubMed Mentions: 4 Fields:
Pha Pharmacology
Translation:Animals
Neonatal thyroid status in an area of iodine sufficiency. J Endocrinol Invest. 2011 Mar; 34(3):197-200. Azizi F, Hosseini MS, Amouzegar A, Tohidi M, Ainy E. PMID: 20959719.

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