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Ariel Linden, DrPH

TitleResearch Specialist
SchoolUCSF School of Medicine
DepartmentMedicine
Address
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    University of California, Los AngelesDrPH1997Health Services

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    Dr. Linden is a health services researcher with expertise in research methods. His particular area of interest is in developing and applying causal inferential techniques to evaluate the effectiveness of healthcare interventions. His recent work has focused on applying machine learning techniques to improve causal inference and risk prediction.


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Linden A, Yarnold PR. Estimating causal effects for survival (time-to-event) outcomes by combining classification tree analysis and propensity score weighting. J Eval Clin Pract. 2017 Dec 12. PMID: 29230910.
      View in: PubMed
    2. Linden A, Yarnold PR. Identifying causal mechanisms in health care interventions using classification tree analysis. J Eval Clin Pract. 2017 Nov 03. PMID: 29105259.
      View in: PubMed
    3. Kullgren JT, Krupka E, Schachter A, Linden A, Miller J, Acharya Y, Alford J, Duffy R, Adler-Milstein J. Precommitting to choose wisely about low-value services: a stepped wedge cluster randomised trial. BMJ Qual Saf. 2017 Oct 24. PMID: 29066616.
      View in: PubMed
    4. Linden A, Yarnold PR. Minimizing imbalances on patient characteristics between treatment groups in randomized trials using classification tree analysis. J Eval Clin Pract. 2017 Jul 04. PMID: 28675602.
      View in: PubMed
    5. Linden A, Yarnold PR. Modeling time-to-event (survival) data using classification tree analysis. J Eval Clin Pract. 2017 Jul 03. PMID: 28670833.
      View in: PubMed
    6. Linden A, Yarnold PR. Using classification tree analysis to generate propensity score weights. J Eval Clin Pract. 2017 Aug; 23(4):703-712. PMID: 28371206.
      View in: PubMed
    7. Linden A. Improving causal inference with a doubly robust estimator that combines propensity score stratification and weighting. J Eval Clin Pract. 2017 Aug; 23(4):697-702. PMID: 28116816.
      View in: PubMed
    8. Linden A. A comparison of approaches for stratifying on the propensity score to reduce bias. J Eval Clin Pract. 2017 Aug; 23(4):690-696. PMID: 28074629.
      View in: PubMed
    9. Linden A . A comprehensive set of post-estimation measures to enrich interrupted time series analysis. Stata Journal. 2017; 17(1):73–88.
    10. Linden A. Persistent threats to validity in single-group interrupted time series analysis with a cross over design. J Eval Clin Pract. 2017 Apr; 23(2):419-425. PMID: 27804216.
      View in: PubMed
    11. Linden A. Challenges to validity in single-group interrupted time series analysis. J Eval Clin Pract. 2017 Apr; 23(2):413-418. PMID: 27630090.
      View in: PubMed
    12. Linden A, Yarnold PR. Combining machine learning and propensity score weighting to estimate causal effects in multivalued treatments. J Eval Clin Pract. 2016 Dec; 22(6):871-881. PMID: 27421786.
      View in: PubMed
    13. Linden A, Yarnold PR. Combining machine learning and matching techniques to improve causal inference in program evaluation. J Eval Clin Pract. 2016 Dec; 22(6):864-870. PMID: 27353301.
      View in: PubMed
    14. Linden A, Yarnold PR, Nallamothu BK. Using machine learning to model dose-response relationships. J Eval Clin Pract. 2016 Dec; 22(6):856-863. PMID: 27240883.
      View in: PubMed
    15. Linden A, Yarnold PR. Using machine learning to identify structural breaks in single-group interrupted time series designs. J Eval Clin Pract. 2016 Dec; 22(6):851-855. PMID: 27091355.
      View in: PubMed
    16. Linden A, Yarnold PR. Using machine learning to assess covariate balance in matching studies. J Eval Clin Pract. 2016 Dec; 22(6):844-850. PMID: 27004916.
      View in: PubMed
    17. Linden A, Yarnold PR. Using data mining techniques to characterize participation in observational studies. J Eval Clin Pract. 2016 Dec; 22(6):835-843. PMID: 26805004.
      View in: PubMed
    18. Linden A. Estimating Measurement Error of the Patient Activation Measure for Respondents with Partially Missing Data. Biomed Res Int. 2015; 2015:270168. PMID: 26636096; PMCID: PMC4655275.
    19. Linden A, Uysal SD, Ryan A, Adams JL. Estimating causal effects for multivalued treatments: a comparison of approaches. Stat Med. 2016 Feb 20; 35(4):534-52. PMID: 26482211.
      View in: PubMed
    20. Linden A . Conducting interrupted time-series analysis for single- and multiple-group comparisons. Stata Journal. 2015; 15(2):480-500.
    21. Linden A. Graphical displays for assessing covariate balance in matching studies. J Eval Clin Pract. 2015 Apr; 21(2):242-7. PMID: 25545944.
      View in: PubMed
    22. Linden A, Butterworth S. A comprehensive hospital-based intervention to reduce readmissions for chronically ill patients: a randomized controlled trial. Am J Manag Care. 2014 Oct; 20(10):783-92. PMID: 25365681.
      View in: PubMed
    23. Linden A. Combining propensity score-based stratification and weighting to improve causal inference in the evaluation of health care interventions. J Eval Clin Pract. 2014 Dec; 20(6):1065-71. PMID: 25266868.
      View in: PubMed
    24. Linden A. Assessing regression to the mean effects in health care initiatives. BMC Med Res Methodol. 2013 Sep 28; 13:119. PMID: 24073634; PMCID: PMC3849564.
    25. Linden A, Samuels SJ. Using balance statistics to determine the optimal number of controls in matching studies. J Eval Clin Pract. 2013 Oct; 19(5):968-75. PMID: 23910956.
      View in: PubMed
    26. Elissen AM, Adams JL, Spreeuwenberg M, Duimel-Peeters IG, Spreeuwenberg C, Linden A, Vrijhoef HJ. Advancing current approaches to disease management evaluation: capitalizing on heterogeneity to understand what works and for whom. BMC Med Res Methodol. 2013 Mar 14; 13:40. PMID: 23497125; PMCID: PMC3626873.
    27. Linden A, Samuels SJ. Estimating measurement error when annualizing health care costs. J Eval Clin Pract. 2013 Oct; 19(5):933-7. PMID: 22844978.
      View in: PubMed
    28. Linden A, Adams JL. Combining the regression discontinuity design and propensity score-based weighting to improve causal inference in program evaluation. J Eval Clin Pract. 2012 Apr; 18(2):317-25. PMID: 22304484.
      View in: PubMed
    29. Linden A. Identifying spin in health management evaluations. J Eval Clin Pract. 2011 Dec; 17(6):1223-30. PMID: 21210897.
      View in: PubMed
    30. Linden A, Adams JL. Applying a propensity score-based weighting model to interrupted time series data: improving causal inference in programme evaluation. J Eval Clin Pract. 2011 Dec; 17(6):1231-8. PMID: 20973870.
      View in: PubMed
    31. Linden A. Designing a prospective study when randomization is not feasible. Eval Health Prof. 2011 Jun; 34(2):164-80. PMID: 20696741.
      View in: PubMed
    32. Linden A, Biuso TJ, Butterworth SW. Help patients with chronic kidney disease stave off dialysis. J Fam Pract. 2010 Apr; 59(4):212-9. PMID: 20398579.
      View in: PubMed
    33. Linden A, Adams JL. Evaluating health management programmes over time: application of propensity score-based weighting to longitudinal data. J Eval Clin Pract. 2010 Feb; 16(1):180-5. PMID: 20367830.
      View in: PubMed
    34. Linden A, Adams JL. Using propensity score-based weighting in the evaluation of health management programme effectiveness. J Eval Clin Pract. 2010 Feb; 16(1):175-9. PMID: 20367829.
      View in: PubMed
    35. Linden A, Butterworth SW, Prochaska JO. Motivational interviewing-based health coaching as a chronic care intervention. J Eval Clin Pract. 2010 Feb; 16(1):166-74. PMID: 20367828.
      View in: PubMed
    36. Couto JE, Webster L, Romney MC, Leider HL, Linden A. Use of an algorithm applied to urine drug screening to assess adherence to an oxycontin regimen. J Opioid Manag. 2009 Nov-Dec; 5(6):359-64. PMID: 20073409.
      View in: PubMed
    37. Linden A, Adams JL. Improving participant selection in disease management programmes: insights gained from propensity score stratification. J Eval Clin Pract. 2008 Oct; 14(5):914-8. PMID: 19018926.
      View in: PubMed
    38. Linden A. Disease management: truth in advertising. Health Aff (Millwood). 2008 Sep-Oct; 27(5):1482-3; author reply 1483-4. PMID: 18780941.
      View in: PubMed
    39. Linden A. Narrow model. Health Aff (Millwood). 2008 May-Jun; 27(3):899-900; author reply 900. PMID: 18474995.
      View in: PubMed
    40. Linden A. Sample size in disease management program evaluation: the challenge of demonstrating a statistically significant reduction in admissions. Dis Manag. 2008 Apr; 11(2):95-101. PMID: 18393649.
      View in: PubMed
    41. Rastogi A, Linden A, Nissenson AR. Disease management in chronic kidney disease. Adv Chronic Kidney Dis. 2008 Jan; 15(1):19-28. PMID: 18155106.
      View in: PubMed
    42. Linden A, Adler-Milstein J. Medicare disease management in policy context. Health Care Financ Rev. 2008; 29(3):1-11. PMID: 18567239; PMCID: PMC4195041.
    43. Linden A, Goldberg S. The case-mix of chronic illness hospitalization rates in a managed care population: implications for health management programmes. J Eval Clin Pract. 2007 Dec; 13(6):947-51. PMID: 18070267.
      View in: PubMed
    44. Linden A, Berg GD, Wadhwa S. Evaluation of a medicaid asthma disease management program. Dis Manag. 2007 Oct; 10(5):266-72. PMID: 17961079.
      View in: PubMed
    45. Linden A, Adams JL. Determining if disease management saves money: an introduction to meta-analysis. J Eval Clin Pract. 2007 Jun; 13(3):400-7. PMID: 17518806.
      View in: PubMed
    46. Biuso TJ, Butterworth S, Linden A. A conceptual framework for targeting prediabetes with lifestyle, clinical, and behavioral management interventions. Dis Manag. 2007 Feb; 10(1):6-15. PMID: 17309360.
      View in: PubMed
    47. Linden A, Trochim WM, Adams JL. Evaluating program effectiveness using the regression point displacement design. Eval Health Prof. 2006 Dec; 29(4):407-23. PMID: 17102063.
      View in: PubMed
    48. Butterworth S, Linden A, McClay W, Leo MC. Effect of motivational interviewing-based health coaching on employees' physical and mental health status. J Occup Health Psychol. 2006 Oct; 11(4):358-65. PMID: 17059299.
      View in: PubMed
    49. Linden A. Is Israel ready for disease management? Isr Med Assoc J. 2006 Oct; 8(10):667-71. PMID: 17125109.
      View in: PubMed
    50. Linden A, Butterworth SW, Roberts N. Disease management interventions II: What else is in the black box? Dis Manag. 2006 Apr; 9(2):73-85. PMID: 16620193.
      View in: PubMed
    51. Linden A. What will it take for disease management to demonstrate a return on investment? New perspectives on an old theme. Am J Manag Care. 2006 Apr; 12(4):217-22. PMID: 16610923.
      View in: PubMed
    52. Linden A, Adams JL. Evaluating disease management programme effectiveness: an introduction to instrumental variables. J Eval Clin Pract. 2006 Apr; 12(2):148-54. PMID: 16579823.
      View in: PubMed
    53. Linden A, Adams JL, Roberts N. Strengthening the case for disease management effectiveness: un-hiding the hidden bias. J Eval Clin Pract. 2006 Apr; 12(2):140-7. PMID: 16579822.
      View in: PubMed
    54. Linden A. Measuring diagnostic and predictive accuracy in disease management: an introduction to receiver operating characteristic (ROC) analysis. J Eval Clin Pract. 2006 Apr; 12(2):132-9. PMID: 16579821.
      View in: PubMed
    55. Linden A, Adams JL, Roberts N. Evaluating disease management programme effectiveness: an introduction to the regression discontinuity design. J Eval Clin Pract. 2006 Apr; 12(2):124-31. PMID: 16579820.
      View in: PubMed
    56. Linden A, Roberts N. Using visual displays as a tool to demonstrate disease management program effectiveness. Dis Manag. 2005 Oct; 8(5):301-10. PMID: 16212515.
      View in: PubMed
    57. Linden A, Wilson T. Letter regarding article by Galbreath et al, "Long-term healthcare and cost outcomes of disease management in a large, randomized, community-based population with heart failure". Circulation. 2005 Jul 05; 112(1):e11; author reply e11. PMID: 15998687.
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    58. Wilson T, Linden A. Potential bias in "controls" used in a heart failure disease-management program. J Am Geriatr Soc. 2005 Jul; 53(7):1268-9. PMID: 16108960.
      View in: PubMed
    59. Wilson T, Linden A. Financial interests, detailed description of methods, and use of randomized design in a real-world setting. Am J Manag Care. 2005 Jun; 11(6):384; author reply 394. PMID: 15974557.
      View in: PubMed
    60. Wilson T, Linden A. Asthma disease management: regression to the mean or better? Am J Manag Care. 2005 Mar; 11(3):136; author reply 136-7. PMID: 15786850.
      View in: PubMed
    61. Wilson T, Linden A. Disease management's economic impact: unproven? Health Aff (Millwood). 2005 Mar-Apr; 24(2):566-7; author reply 567. PMID: 15757944.
      View in: PubMed
    62. Linden A, Wilson T. Care management for heart failure. Ann Intern Med. 2005 Mar 01; 142(5):386; author reply 386. PMID: 15738460.
      View in: PubMed
    63. Linden A, Roberts N. A user's guide to the disease management literature: recommendations for reporting and assessing program outcomes. Am J Manag Care. 2005 Feb; 11(2):113-20. PMID: 15726859.
      View in: PubMed
    64. Wilson T, Linden A. Measuring diabetes management. Health Aff (Millwood). 2004 Nov-Dec; 23(6):277-8; author reply 278-9. PMID: 15537618.
      View in: PubMed
    65. Linden A, Adams JL, Roberts N. Generalizing disease management program results: how to get from here to there. Manag Care Interface. 2004 Jul; 17(7):38-45. PMID: 15341247.
      View in: PubMed
    66. Linden A, Adams JL, Roberts N. Using an empirical method for establishing clinical outcome targets in disease management programs. Dis Manag. 2004; 7(2):93-101. PMID: 15228794.
      View in: PubMed
    67. Linden A, Roberts N. Disease management interventions: what's in the black box? Dis Manag. 2004; 7(4):275-91. PMID: 15671785.
      View in: PubMed
    68. Linden A, Adams JL, Roberts N. Evaluating disease management program effectiveness: an introduction to survival analysis. Dis Manag. 2004; 7(3):180-90. PMID: 15669578.
      View in: PubMed
    69. Linden A, Adams JL, Roberts N. Evaluating disease management program effectiveness: an introduction to time-series analysis. Dis Manag. 2003; 6(4):243-55. PMID: 14736348.
      View in: PubMed
    70. Linden A, Adams JL, Roberts N. An assessment of the total population approach for evaluating disease management program effectiveness. Dis Manag. 2003; 6(2):93-102. PMID: 14577903.
      View in: PubMed
    71. Linden A, Roberts N, Keck K. The complete "how to" guide for selecting a disease management vendor. Dis Manag. 2003; 6(1):21-6. PMID: 12899564.
      View in: PubMed
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