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Edward Chu, MD

Photo of Edward Chu, MD
Title(s)HS Clinical Professor, Pediatrics
SchoolSchool of Medicine
Address3333 California Street
San Francisco CA 94118
Phone510-428-3885 ext. 4997
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Targeting YES1 enhances the efficacy of chemotherapy, targeted therapy and onco-immunotherapy. Cell Signal. 2025 Dec; 136:112108. Zheng D, Wang Y, Li J, Zhang G, Chu E, Wei N. PMID: 40907631.
      View in: PubMed   Mentions: 1     Fields:    
    2. Facilitated Versus Patient-Directed Advance Care Planning Among Patients With Advanced Cancer: A Randomized Clinical Trial. JCO Oncol Pract. 2025 Oct; 21(10):1447-1457. Schenker Y, Belin SC, Wang T, Sudore RL, Hammes B, Arnold RM, Flowers R, Chiu E, Hall J, Dudley-Morrissey Y, Ferrell B, Crowley-Matoka M, Brufsky A, Chu E, Gorantla V, Mehta D, Thomas R, Yee M, White D. PMID: 40106743; PMCID: PMC12353131.
      View in: PubMed   Mentions: 1     Fields:    
    3. Phase I trial of ATR inhibitor elimusertib with FOLFIRI in advanced or metastatic gastrointestinal malignancies (ETCTN 10406). Cancer Chemother Pharmacol. 2025 Jan 22; 95(1):27. Krishnamurthy A, Wang H, Rhee JC, Davar D, Moy RH, Ratner L, Christner SM, Holleran JL, Deppas J, Sclafani C, Schmitz JC, Gore S, Chu E, Bakkenist CJ, Beumer JH, Villaruz LC. PMID: 39841295; PMCID: PMC12183696.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    4. Dose finding, bioavailability, and PK-PD of oral triapine with concurrent chemoradiation for locally advanced cervical cancer and vaginal cancer (ETCTN 9892). Cancer Chemother Pharmacol. 2024 Dec 14; 95(1):4. Taylor SE, Behr S, Cooper KL, Mahdi H, Fabian D, Gallion H, Ueland F, Vargo J, Orr B, Girda E, Courtney-Brooks M, Olawaiye AB, Randall LM, Richardson DL, Sullivan SA, Huang M, Christner SM, Beriwal S, Lin Y, Chauhan A, Chu E, Kohn EC, Kunos C, Ivy SP, Beumer JH. PMID: 39673591; PMCID: PMC12183685.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    5. FAK loss reduces BRAFV600E-induced ERK phosphorylation to promote intestinal stemness and cecal tumor formation. Elife. 2024 Jun 26; 13. Gao C, Ge H, Kuan SF, Cai C, Lu X, Esni F, Schoen RE, Wang JH, Chu E, Hu J. PMID: 38921956; PMCID: PMC11208045.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    6. Associations of Health Care Utilization and Therapeutic Alliance in Patients with Advanced Cancer. J Palliat Med. 2024 04; 27(4):515-520. Bell SG, Althouse AD, Belin SC, Arnold RM, Smith KJ, White DB, Chu E, Schenker Y, Thomas TH. PMID: 38574330; PMCID: PMC11265618.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. FAK loss reduces BRAFV600E-induced ERK phosphorylation to promote intestinal stemness and cecal tumor formation. Res Sq. 2024 Jan 05. Gao C, Ge H, Kuan SF, Cai C, Lu X, Esni F, Schoen R, Wang J, Chu E, Hu J. PMID: 36778401; PMCID: PMC9915899.
      View in: PubMed   Mentions:
    8. BRAFV600E mutation and DSS treatment synergize to induce cecal tumor formation in mice. Biochem Biophys Rep. 2024 Mar; 37:101634. Gao C, Esni F, Chu E, Hu J. PMID: 38188365; PMCID: PMC10771891.
      View in: PubMed   Mentions:
    9. Inotropes to Differentiate Dense Spontaneous Echo Contrast From Thrombus in the Left Atrial Appendage. JACC Clin Electrophysiol. 2023 12; 9(12):2655-2657. Pandey AC, Shen CP, Chu E, Della Rocca D, Janczyk G, Pangborn K, Natale A, Price MJ, Gibson D, Reddy VY. PMID: 38032576.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Scutellaria baicalensis enhances 5-fluorouracil-based chemotherapy via inhibition of proliferative signaling pathways. Cell Commun Signal. 2023 06 19; 21(1):147. Liu H, Liu H, Zhou Z, Chung J, Zhang G, Chang J, Parise RA, Chu E, Schmitz JC. PMID: 37337282; PMCID: PMC10278337.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    11. Quassinoid analogs exert potent antitumor activity via reversible protein biosynthesis inhibition in human colorectal cancer. Biochem Pharmacol. 2023 06; 212:115564. Wei N, Burnett J, Crocker DL, Huang Y, Li S, Wipf P, Chu E, Schmitz JC. PMID: 37116665; PMCID: PMC11225567.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    12. Primary Palliative Care Improves Uptake of Advance Care Planning Among Patients With Advanced Cancers. J Natl Compr Canc Netw. 2023 04; 21(4):383-390. Cohen MG, Althouse AD, Arnold RM, White D, Chu E, Rosenzweig M, Smith KJ, Schenker Y. PMID: 37015338; PMCID: PMC10477933.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    13. Study of efficacy and longevity of immune response to third and fourth doses of COVID-19 vaccines in patients with cancer: A single arm clinical trial. Elife. 2023 03 28; 12. Thakkar A, Pradhan K, Duva B, Carreno JM, Sahu S, Thiruthuvanathan V, Campbell S, Gallego S, Bhagat TD, Rivera J, Choudhary G, Olea R, Sabalza M, Shapiro LC, Lee M, Quinn R, Mantzaris I, Chu E, Will B, Pirofski LA, Krammer F, Verma A, Halmos B. PMID: 36975207; PMCID: PMC10129324.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCellsCTClinical Trials
    14. Emerging roles of Aurora-A kinase in cancer therapy resistance. Acta Pharm Sin B. 2023 Jul; 13(7):2826-2843. Zheng D, Li J, Yan H, Zhang G, Li W, Chu E, Wei N. PMID: 37521867; PMCID: PMC10372834.
      View in: PubMed   Mentions: 34  
    15. A phase 1 study of veliparib (ABT-888) plus weekly carboplatin and paclitaxel in advanced solid malignancies, with an expansion cohort in triple negative breast cancer (TNBC) (ETCTN 8620). Breast Cancer Res Treat. 2023 Apr; 198(3):487-498. Malhotra MK, Pahuja S, Kiesel BF, Appleman LJ, Ding F, Lin Y, Tawbi HA, Stoller RG, Lee JJ, Belani CP, Chen AP, Giranda VL, Shepherd SP, Emens LA, Ivy SP, Chu E, Beumer JH, Puhalla S. PMID: 36853577; PMCID: PMC10710035.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    16. Examining Caregiver Outcomes in the CONNECT Intervention for Patients With Advanced Cancer. J Pain Symptom Manage. 2023 03; 65(3):173-182. Semere W, Althouse AD, Arnold R, White D, Smith TJ, Chu E, Rosenzweig MQ, Schenker Y. PMID: 36503155; PMCID: PMC10191108.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. Symptom Burden and Shared Care Planning in an Oncology Nurse-Led Primary Palliative Care Intervention (CONNECT) for Patients with Advanced Cancer. J Palliat Med. 2023 05; 26(5):667-673. Mitchell CJ, Althouse A, Feldman R, Arnold RM, Rosenzweig M, Smith K, Chu E, White D, Smith T, Schenker Y. PMID: 36472545; PMCID: PMC10150730.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. All Optimal Dosing Roads Lead to Therapeutic Drug Monitoring-Why Take the Slow Lane. JAMA Oncol. 2022 12 01; 8(12):1733-1735. Beumer JH, Chu E, Salamone SJ. PMID: 36264552; PMCID: PMC9772116.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    19. mTOR participates in the formation, maintenance, and function of memory CD8+T cells regulated by glycometabolism. Biochem Pharmacol. 2022 Oct; 204:115197. Cai X, Li H, Wang M, Chu E, Wei N, Lin J, Hu Y, Dai J, Chen A, Zheng H, Zhang Q, Zhong Y, Chang R, Wu S, Xiao Y, Liu C. PMID: 35926651.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    20. Burnout Among Oncology Nurses: The Effects of Providing a Primary Palliative Care Intervention Using CONNECT Protocol. Clin J Oncol Nurs. 2022 07 25; 26(4):391-398. Cohen JB, Reiser VL, Althouse AD, Resick JM, Chu E, Smith TJ, Arnold RM, Rosenzweig MQ, Schenker Y. PMID: 35939720; PMCID: PMC11460563.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. A phase 1 and pharmacodynamic study of chronically-dosed, single-agent veliparib (ABT-888) in patients with BRCA1- or BRCA2-mutated cancer or platinum-refractory ovarian or triple-negative breast cancer. Cancer Chemother Pharmacol. 2022 05; 89(5):721-735. Manzo J, Puhalla S, Pahuja S, Ding F, Lin Y, Appleman L, Tawbi H, Stoller R, Lee JJ, Diergaarde B, Kiesel BF, Yu J, Tan AR, Belani CP, Chew H, Garcia AA, Morgan RJ, Wahner Hendrickson AE, Visscher DW, Hurley RM, Kaufmann SH, Swisher EM, Oesterreich S, Katz T, Ji J, Zhang Y, Parchment RE, Chen A, Duan W, Giranda V, Shepherd SP, Ivy SP, Chu E, Beumer JH, ETCTN-8282 study team. PMID: 35435472; PMCID: PMC9116722.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    22. Impact of COVID-19 on case fatality rate of patients with cancer during the Omicron wave. Cancer Cell. 2022 04 11; 40(4):343-345. Lee M, Quinn R, Pradhan K, Fedorov K, Levitz D, Fromowitz A, Thakkar A, Shapiro LC, Kabarriti R, Ruiz RE, Andrews EM, Thota R, Chu E, Kalnicki S, Goldstein Y, Loeb D, Racine A, Halmos B, Mehta V, Verma A. PMID: 35219358; PMCID: PMC8860706.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    23. Framework for opioid stigma in cancer pain. Pain. 2022 02 01; 163(2):e182-e189. Bulls HW, Chu E, Goodin BR, Liebschutz JM, Wozniak A, Schenker Y, Merlin JS. PMID: 34010940; PMCID: PMC8589872.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    24. Pembrolizumab plus azacitidine in patients with chemotherapy refractory metastatic colorectal cancer: a single-arm phase 2 trial and correlative biomarker analysis. Clin Epigenetics. 2022 01 06; 14(1):3. Kuang C, Park Y, Augustin RC, Lin Y, Hartman DJ, Seigh L, Pai RK, Sun W, Bahary N, Ohr J, Rhee JC, Marks SM, Beasley HS, Shuai Y, Herman JG, Zarour HM, Chu E, Lee JJ, Krishnamurthy A. PMID: 34991708; PMCID: PMC8740438.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCTClinical Trials
    25. Hope and advance care planning in advanced cancer: Is there a relationship? Cancer. 2022 Mar 15; 128(6):1339-1345. Cohen MG, Althouse AD, Arnold RM, Bulls HW, White DB, Chu E, Rosenzweig MQ, Smith KJ, Schenker Y. PMID: 34787930; PMCID: PMC8882158.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    26. Effects of an Oncology Nurse-Led, Primary Palliative Care Intervention (CONNECT) on Illness Expectations Among Patients With Advanced Cancer. JCO Oncol Pract. 2022 04; 18(4):e504-e515. Sigler LE, Althouse AD, Thomas TH, Arnold RM, White D, Smith TJ, Chu E, Rosenzweig M, Smith KJ, Schenker Y. PMID: 34767474; PMCID: PMC9014423.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    27. The Effects of Hyperbaric Oxygen Therapy in Patients with Central Retinal Artery Occlusion: A Retrospective Study, Systematic Review, and Meta-analysis. Korean J Ophthalmol. 2022 04; 36(2):108-113. Rosignoli L, Chu ER, Carter JE, Johnson DA, Sohn JH, Bahadorani S. PMID: 34743490; PMCID: PMC9013555.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    28. How does the level of pulmonary venous isolation compare between pulsed field ablation and thermal energy ablation (radiofrequency, cryo, or laser)? Europace. 2021 11 08; 23(11):1757-1766. Kawamura I, Neuzil P, Shivamurthy P, Kuroki K, Lam J, Musikantow D, Chu E, Turagam MK, Minami K, Funasako M, Petru J, Choudry S, Miller MA, Langan MN, Whang W, Dukkipati SR, Koruth JS, Reddy VY. PMID: 34151947; PMCID: PMC8576283.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCTClinical Trials
    29. Effect of an Oncology Nurse-Led Primary Palliative Care Intervention on Patients With Advanced Cancer: The CONNECT Cluster Randomized Clinical Trial. JAMA Intern Med. 2021 11 01; 181(11):1451-1460. Schenker Y, Althouse AD, Rosenzweig M, White DB, Chu E, Smith KJ, Resick JM, Belin S, Park SY, Smith TJ, Bakitas MA, Arnold RM. PMID: 34515737; PMCID: PMC8438619.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    30. Phase 1 study of safety, pharmacokinetics, and pharmacodynamics of tivantinib in combination with bevacizumab in adult patients with advanced solid tumors. Cancer Chemother Pharmacol. 2021 10; 88(4):643-654. Maguire WF, Schmitz JC, Scemama J, Czambel K, Lin Y, Green AG, Wu S, Lin H, Puhalla S, Rhee J, Stoller R, Tawbi H, Lee JJ, Wright JJ, Beumer JH, Chu E, Appleman LJ, ETCTN-9153 Study Team. PMID: 34164713; PMCID: PMC8628145.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    31. Protective Role of 360° Laser Retinopexy in Patients with Rhegmatogenous Retinal Detachment: a Systematic Review and Meta-analysis. Korean J Ophthalmol. 2021 06; 35(3):215-222. Soekamto C, Chu ER, Johnson DA, Sohn JH, Bahadorani S. PMID: 34120420; PMCID: PMC8200595.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    32. Barriers and financial impact of same-day discharge after atrial fibrillation ablation. Pacing Clin Electrophysiol. 2021 04; 44(4):711-719. Chu E, Zhang C, Musikantow DR, Turagam MK, Langan N, Sofi A, Choudry S, Syros G, Miller MA, Koruth JS, Whang W, Dukkipati SR, Reddy VY. PMID: 33686695.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    33. Stronger therapeutic alliance is associated with better quality of life among patients with advanced cancer. Psychooncology. 2021 07; 30(7):1086-1094. Thomas T, Althouse A, Sigler L, Arnold R, Chu E, White DB, Rosenzweig M, Smith K, Smith TJ, Schenker Y. PMID: 33547717; PMCID: PMC9243649.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    34. Atrial Fibrillation in Patients Hospitalized With COVID-19: Incidence, Predictors, Outcomes, and Comparison to Influenza. JACC Clin Electrophysiol. 2021 09; 7(9):1120-1130. Musikantow DR, Turagam MK, Sartori S, Chu E, Kawamura I, Shivamurthy P, Bokhari M, Oates C, Zhang C, Pumill C, Malick W, Hashemi H, Ruiz-Maya T, Hadley MB, Gandhi J, Sperling D, Whang W, Koruth JS, Langan MN, Sofi A, Gomes A, Harcum S, Cammack S, Ellsworth B, Dukkipati SR, Bassily-Marcus A, Kohli-Seth R, Goldman ME, Halperin JL, Fuster V, Reddy VY. PMID: 33895107; PMCID: PMC7904279.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    35. The Association Between Area Deprivation Index and Patient-Reported Outcomes in Patients with Advanced Cancer. Health Equity. 2021; 5(1):8-16. Rosenzweig MQ, Althouse AD, Sabik L, Arnold R, Chu E, Smith TJ, Smith K, White D, Schenker Y. PMID: 33564735; PMCID: PMC7868579.
      View in: PubMed   Mentions: 34  
    36. Poor patient health is associated with higher caregiver burden for older adults with advanced cancer. J Geriatr Oncol. 2021 06; 12(5):771-778. Semere W, Althouse AD, Rosland AM, White D, Arnold R, Chu E, Smith TJ, Schenker Y. PMID: 33478890; PMCID: PMC8184574.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    37. Malignant Arrhythmias in Patients With COVID-19: Incidence, Mechanisms, and Outcomes. Circ Arrhythm Electrophysiol. 2020 11; 13(11):e008920. Turagam MK, Musikantow D, Goldman ME, Bassily-Marcus A, Chu E, Shivamurthy P, Lampert J, Kawamura I, Bokhari M, Whang W, Bier BA, Malick W, Hashemi H, Miller MA, Choudry S, Pumill C, Ruiz-Maya T, Hadley M, Giustino G, Koruth JS, Langan N, Sofi A, Dukkipati SR, Halperin JL, Fuster V, Kohli-Seth R, Reddy VY. PMID: 33026892; PMCID: PMC7668347.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    38. In vitro evaluation of the metabolic enzymes and drug interaction potential of triapine. Cancer Chemother Pharmacol. 2020 11; 86(5):633-640. Joshi A, Kiesel BF, Chaphekar N, Jones R, Guo J, Kunos CA, Taylor S, Chu E, Venkataramanan R, Beumer JH. PMID: 32989483; PMCID: PMC7906094.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    39. Evaluation of the pharmacokinetic drug-drug interaction potential of iohexol, a renal filtration marker. Cancer Chemother Pharmacol. 2020 10; 86(4):535-545. Joshi A, Guo J, Holleran JL, Kiesel B, Taylor S, Christner S, Parise RA, Miller BM, Ivy SP, Chu E, Venkataramanan R, Beumer JH. PMID: 32948918; PMCID: PMC7521612.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    40. Relationships Between Advanced Cancer Patients' Worry About Dying and Illness Understanding, Treatment Preferences, and Advance Care Planning. J Pain Symptom Manage. 2021 04; 61(4):723-731.e1. Rodenbach RA, Althouse AD, Schenker Y, Smith TJ, Chu E, White DB, Bakitas M, Arnold RM. PMID: 32926962; PMCID: PMC7952460.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    41. Syncope and presyncope in patients with COVID-19. Pacing Clin Electrophysiol. 2020 10; 43(10):1139-1148. Oates CP, Turagam MK, Musikantow D, Chu E, Shivamurthy P, Lampert J, Kawamura I, Bokhari M, Whang W, Miller MA, Choudry S, Langan N, Sofi A, Dukkipati SR, Reddy VY, Koruth JS. PMID: 32840325; PMCID: PMC7461520.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCellsPHPublic Health
    42. Patient-centered and efficacious advance care planning in cancer: Protocol and key design considerations for the PEACe-compare trial. Contemp Clin Trials. 2020 09; 96:106071. Resick JM, Arnold RM, Sudore RL, Farrell D, Belin S, Althouse AD, Ferrell B, Hammes BJ, Chu E, White DB, Rak KJ, Schenker Y. PMID: 32739493; PMCID: PMC7510772.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    43. Treatment of Colorectal Cancer and Other GI Cancers in the COVID-19 Pandemic. Clin Colorectal Cancer. 2020 09; 19(3):145. Chu E. PMID: 32788050; PMCID: PMC7377980.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    44. The UPMC Hillman Cancer Center Approach to the Management of Colorectal Cancer During the COVID-19 Pandemic Era. Clin Colorectal Cancer. 2020 09; 19(3):146-148. Lee JJ, Chu E. PMID: 32811719; PMCID: PMC7347322.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    45. Quantitation of iohexol, a glomerular filtration marker, in human plasma by LC-MS/MS. J Pharm Biomed Anal. 2020 Sep 10; 189:113464. Holleran JL, Parise RA, Guo J, Kiesel BF, Taylor SE, Ivy SP, Chu E, Beumer JH. PMID: 32659569; PMCID: PMC7484441.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    46. Is Advance Care Planning Associated With Decreased Hope in Advanced Cancer? JCO Oncol Pract. 2021 02; 17(2):e248-e256. Cohen MG, Althouse AD, Arnold RM, Bulls HW, White D, Chu E, Rosenzweig M, Smith K, Schenker Y. PMID: 32530807; PMCID: PMC8258003.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    47. Phase 1 study of veliparib (ABT-888), a poly (ADP-ribose) polymerase inhibitor, with carboplatin and paclitaxel in advanced solid malignancies. Cancer Chemother Pharmacol. 2019 12; 84(6):1289-1301. Appleman LJ, Beumer JH, Jiang Y, Lin Y, Ding F, Puhalla S, Swartz L, Owonikoko TK, Donald Harvey R, Stoller R, Petro DP, Tawbi HA, Argiris A, Strychor S, Pouquet M, Kiesel B, Chen AP, Gandara D, Belani CP, Chu E, Ramalingam SS. PMID: 31549216; PMCID: PMC7825275.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    48. Treatment of central serous chorioretinopathy with topical NSAIDs. Clin Ophthalmol. 2019; 13:1543-1548. Bahadorani S, Maclean K, Wannamaker K, Chu ER, Gresores N, Sohn JH, Diaz-Rohena R, Singer MA. PMID: 31616132; PMCID: PMC6699520.
      View in: PubMed   Mentions: 7  
    49. PYK2 Is Involved in Premalignant Acinar Cell Reprogramming and Pancreatic Ductal Adenocarcinoma Maintenance by Phosphorylating β-CateninY654. Cell Mol Gastroenterol Hepatol. 2019; 8(4):561-578. Gao C, Chen G, Zhang DH, Zhang J, Kuan SF, Hu W, Esni F, Gao X, Guan JL, Chu E, Hu J. PMID: 31330317; PMCID: PMC6889497.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    50. The effects of temporary intraocular pressure spikes after intravitreal dexamethasone implantation on the retinal nerve fiber layer. Clin Ophthalmol. 2019; 13:1079-1086. Wannamaker KW, Kenny S, Das R, Mendlovitz A, Comstock JM, Chu ER, Bahadorani S, Gresores NJ, Beck KD, Krambeer CJ, Kermany DS, Diaz-Rohena R, Nolan DP, Sohn JH, Singer MA. PMID: 31417237; PMCID: PMC6602526.
      View in: PubMed   Mentions: 2  
    51. Standardization of Inpatient CPR Status Discussions and Documentation Within the Division of Hematology-Oncology at UPMC Shadyside: Results From PDSA Cycles 1 and 2. J Oncol Pract. 2019 08; 15(8):e746-e754. Garcia CA, Bhatnagar M, Rodenbach R, Chu E, Marks S, Graham-Pardus A, Kriner J, Winfield M, Minnier C, Leahy J, Hanchett S, Baird E, Arnold RM, Levenson JE. PMID: 31206337.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    52. Quantitation of paclitaxel, and its 6-alpha-OH and 3-para-OH metabolites in human plasma by LC-MS/MS. J Pharm Biomed Anal. 2019 Aug 05; 172:26-32. Christner SM, Parise RA, Ivy PS, Tawbi H, Chu E, Beumer JH. PMID: 31022613; PMCID: PMC6548629.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    53. Cancer Biomarkers for Integrative Oncology. Curr Oncol Rep. 2019 03 05; 21(4):32. Ganguly A, Frank D, Kumar N, Cheng YC, Chu E. PMID: 30834992.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    54. A phase 2 trial of regorafenib as a single agent in patients with chemotherapy-refractory, advanced, and metastatic biliary tract adenocarcinoma. Cancer. 2019 03 15; 125(6):902-909. Sun W, Patel A, Normolle D, Patel K, Ohr J, Lee JJ, Bahary N, Chu E, Streeter N, Drummond S. PMID: 30561756; PMCID: PMC6402964.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCTClinical Trials
    55. Targeting colon cancer with the novel STAT3 inhibitor bruceantinol. Oncogene. 2019 03; 38(10):1676-1687. Wei N, Li J, Fang C, Chang J, Xirou V, Syrigos NK, Marks BJ, Chu E, Schmitz JC. PMID: 30348989.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    56. Therapeutic Drug Monitoring in Oncology: International Association of Therapeutic Drug Monitoring and Clinical Toxicology Recommendations for 5-Fluorouracil Therapy. Clin Pharmacol Ther. 2019 03; 105(3):598-613. Beumer JH, Chu E, Allegra C, Tanigawara Y, Milano G, Diasio R, Kim TW, Mathijssen RH, Zhang L, Arnold D, Muneoka K, Boku N, Joerger M. PMID: 29923599; PMCID: PMC6309286.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    57. Recent Advances in the Clinical Development of Immune Checkpoint Blockade Therapy for Mismatch Repair Proficient (pMMR)/non-MSI-H Metastatic Colorectal Cancer. Clin Colorectal Cancer. 2018 12; 17(4):258-273. Lee JJ, Chu E. PMID: 30072278; PMCID: PMC6612427.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    58. How I treat chemorefractory metastatic colorectal cancer. Clin Adv Hematol Oncol. 2018 May; 16(5):340-345. Chu E. PMID: 29851930.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    59. Herbal formula Huang Qin Ge Gen Tang enhances 5-fluorouracil antitumor activity through modulation of the E2F1/TS pathway. Cell Commun Signal. 2018 02 20; 16(1):7. Liu H, Liu H, Zhou Z, Parise RA, Chu E, Schmitz JC. PMID: 29458395; PMCID: PMC5819251.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    60. Total Outflow Facility in Live C57BL/6 Mice of Different Age. Biomed Hub. 2017 Sep-Dec; 2(3):1-10. Yelenskiy A, Ko MK, Chu ER, Gonzalez JM, Siegmund K, Tan JC. PMID: 31988919; PMCID: PMC6945946.
      View in: PubMed   Mentions: 4  
    61. State of the Science: Cancer Complementary and Alternative Medicine Therapeutics Research-NCI Strategic Workshop Highlights of Discussion Report. J Natl Cancer Inst Monogr. 2017 11 01; 2017(52). Xi D, Bao T, Chen Q, Chen S, Cheng YC, Cullen J, Frank DA, Friedberg JW, Kronish I, Lee JE, Levine M, Li P, Li S, Lu W, Mao JJ, O'Keefe S, Rubinstein L, Shah MA, Standish L, Paller CJ, Chu E. PMID: 29140484; PMCID: PMC6061228.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    62. LC-MS/MS assay for the quantitation of the ribonucleotide reductase inhibitor triapine in human plasma. J Pharm Biomed Anal. 2017 Nov 30; 146:154-160. Matsumoto J, Kiesel BF, Parise RA, Guo J, Taylor S, Huang M, Eiseman JL, Ivy SP, Kunos C, Chu E, Beumer JH. PMID: 28881312; PMCID: PMC5636190.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    63. LC-MS/MS assay for the quantitation of the ATR kinase inhibitor VX-970 in human plasma. J Pharm Biomed Anal. 2017 Nov 30; 146:244-250. Kiesel BF, Scemama J, Parise RA, Villaruz L, Iffland A, Doyle A, Ivy P, Chu E, Bakkenist CJ, Beumer JH. PMID: 28888173; PMCID: PMC5632222.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    64. A Pilot Trial of Early Specialty Palliative Care for Patients with Advanced Pancreatic Cancer: Challenges Encountered and Lessons Learned. J Palliat Med. 2018 01; 21(1):28-36. Schenker Y, Bahary N, Claxton R, Childers J, Chu E, Kavalieratos D, King L, Lembersky B, Tiver G, Arnold RM. PMID: 28772092; PMCID: PMC5757080.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    65. Phase I study of veliparib in combination with gemcitabine. Cancer Chemother Pharmacol. 2017 Sep; 80(3):631-643. Stoller R, Schmitz JC, Ding F, Puhalla S, Belani CP, Appleman L, Lin Y, Jiang Y, Almokadem S, Petro D, Holleran J, Kiesel BF, Ken Czambel R, Carneiro BA, Kontopodis E, Hershberger PA, Rachid M, Chen A, Chu E, Beumer JH. PMID: 28770300; PMCID: PMC5734661.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    66. Esophageal Damage During Epicardial Ventricular Tachycardia Ablation. JACC Clin Electrophysiol. 2017 12 11; 3(12):1470-1471. Koruth JS, Chu EW, Bhardwaj R, Dukkipati S, Reddy VY. PMID: 29759680.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    67. Parent-Metabolite Pharmacokinetic Modeling and Pharmacodynamics of Veliparib (ABT-888), a PARP Inhibitor, in Patients With BRCA 1/2-Mutated Cancer or PARP-Sensitive Tumor Types. J Clin Pharmacol. 2017 08; 57(8):977-987. Niu J, Scheuerell C, Mehrotra S, Karan S, Puhalla S, Kiesel BF, Ji J, Chu E, Gopalakrishnan M, Ivaturi V, Gobburu J, Beumer JH. PMID: 28387939; PMCID: PMC5503785.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCellsCTClinical Trials
    68. Phase I Trial of Triapine-Cisplatin-Paclitaxel Chemotherapy for Advanced Stage or Metastatic Solid Tumor Cancers. Front Oncol. 2017; 7:62. Kunos CA, Chu E, Makower D, Kaubisch A, Sznol M, Ivy SP. PMID: 28421163; PMCID: PMC5378786.
      View in: PubMed   Mentions: 7  
    69. Adjuvant Chemotherapy for Stage II Colon Cancer: The Debate Goes On. J Oncol Pract. 2017 04; 13(4):245-246. Lee JJ, Chu E. PMID: 28399385; PMCID: PMC5455155.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    70. Natural History of Conversion of Leber's Hereditary Optic Neuropathy: A Prospective Case Series. Ophthalmology. 2017 06; 124(6):843-850. Hwang TJ, Karanjia R, Moraes-Filho MN, Gale J, Tran JS, Chu ER, Salomao SR, Berezovsky A, Belfort R, Moraes MN, Sadun F, DeNegri AM, La Morgia C, Barboni P, Ramos CDVF, Chicani CF, Quiros PA, Carelli V, Sadun AA. PMID: 28196731.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    71. Adherence, Dosing, and Managing Toxicities With Trifluridine/Tipiracil (TAS-102). Clin Colorectal Cancer. 2017 06; 16(2):85-92. Lee JJ, Chu E. PMID: 28242161; PMCID: PMC5743195.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    72. Systemic Therapy for Metastatic Colorectal Cancer: From Current Standards to Future Molecular Targeted Approaches. Am Soc Clin Oncol Educ Book. 2017; 37:246-256. Atreya CE, Yaeger R, Chu E. PMID: 28561718.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    73. Phase I trial of daily triapine in combination with cisplatin chemotherapy for advanced-stage malignancies. Cancer Chemother Pharmacol. 2017 Jan; 79(1):201-207. Kunos CA, Chu E, Beumer JH, Sznol M, Ivy SP. PMID: 27878356; PMCID: PMC5226891.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    74. Correcting Finger Counting to Snellen Acuity. Neuroophthalmology. 2016 Oct; 40(5):219-221. Karanjia R, Hwang TJ, Chen AF, Pouw A, Tian JJ, Chu ER, Wang MY, Tran JS, Sadun AA. PMID: 27928408; PMCID: PMC5122922.
      View in: PubMed   Mentions: 2  
    75. Tyrosine Kinase and Mammalian Target of Rapamycin Inhibitors in the Treatment of Advanced Renal Cell Carcinoma: Practical Clinical Implications of Pharmacologic Features. Clin Genitourin Cancer. 2017 02; 15(1):7-22. Parikh RA, Appleman LJ, Beumer JH, Matczak E, Chu E. PMID: 27473523.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    76. Therapeutic drug monitoring of 5-fluorouracil. Cancer Chemother Pharmacol. 2016 09; 78(3):447-64. Lee JJ, Beumer JH, Chu E. PMID: 27217046; PMCID: PMC5204259.
      View in: PubMed   Mentions: 81     Fields:    Translation:Humans
    77. Human mass balance study of TAS-102 using (14)C analyzed by accelerator mass spectrometry. Cancer Chemother Pharmacol. 2016 Mar; 77(3):515-26. Lee JJ, Seraj J, Yoshida K, Mizuguchi H, Strychor S, Fiejdasz J, Faulkner T, Parise RA, Fawcett P, Pollice L, Mason S, Hague J, Croft M, Nugteren J, Tedder C, Sun W, Chu E, Beumer JH. PMID: 26787503; PMCID: PMC4767595.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    78. Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells. Oncotarget. 2015 Dec 01; 6(38):40866-79. Wu S, Guo Z, Hopkins CD, Wei N, Chu E, Wipf P, Schmitz JC. PMID: 26506423; PMCID: PMC4747374.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    79. The evaluation of clopidogrel use in perioperative general surgery patients: a prospective randomized controlled trial. Am J Surg. 2016 Jun; 211(6):1019-25. Chu EW, Chernoguz A, Divino CM. PMID: 27002953.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    80. Cost-Effectiveness of Adjuvant Chemotherapy in the Treatment of Early-Stage Colon Cancer. Clin Colorectal Cancer. 2015 Dec; 14(4):219-26. Soni A, Chu E. PMID: 26072443.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    81. The cytotoxic effects of regorafenib in combination with protein kinase D inhibition in human colorectal cancer cells. Oncotarget. 2015 Mar 10; 6(7):4745-56. Wei N, Chu E, Wu SY, Wipf P, Schmitz JC. PMID: 25544765; PMCID: PMC4467112.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    82. Care management by oncology nurses to address palliative care needs: a pilot trial to assess feasibility, acceptability, and perceived effectiveness of the CONNECT intervention. J Palliat Med. 2015 Mar; 18(3):232-40. Schenker Y, White D, Rosenzweig M, Chu E, Moore C, Ellis P, Nikolajski P, Ford C, Tiver G, McCarthy L, Arnold R. PMID: 25517219; PMCID: PMC4347888.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    83. A phase i study of DMS612, a novel bifunctional alkylating agent. Clin Cancer Res. 2015 Feb 15; 21(4):721-9. Appleman LJ, Balasubramaniam S, Parise RA, Bryla C, Redon CE, Nakamura AJ, Bonner WM, Wright JJ, Piekarz R, Kohler DR, Jiang Y, Belani CP, Eiseman J, Chu E, Beumer JH, Bates SE. PMID: 25467180; PMCID: PMC4755291.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    84. What are cancer centers advertising to the public?: a content analysis. Ann Intern Med. 2014 Jun 17; 160(12):813-20. Vater LB, Donohue JM, Arnold R, White DB, Chu E, Schenker Y. PMID: 24863081; PMCID: PMC4356527.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    85. The potential roles of hepatocyte growth factor (HGF)-MET pathway inhibitors in cancer treatment. Onco Targets Ther. 2014; 7:969-83. Parikh RA, Wang P, Beumer JH, Chu E, Appleman LJ. PMID: 24959084; PMCID: PMC4061161.
      View in: PubMed   Mentions: 39  
    86. Sequencing of antiangiogenic agents in the treatment of metastatic colorectal cancer. Clin Colorectal Cancer. 2014 Sep; 13(3):135-44. Lee JJ, Chu E. PMID: 24768040.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    87. Tissue-based imaging model of human trabecular meshwork. J Ocul Pharmacol Ther. 2014 Mar-Apr; 30(2-3):191-201. Chu ER, Gonzalez JM, Tan JC. PMID: 24517246; PMCID: PMC3991999.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    88. Oncologist factors that influence referrals to subspecialty palliative care clinics. J Oncol Pract. 2014 Mar; 10(2):e37-44. Schenker Y, Crowley-Matoka M, Dohan D, Rabow MW, Smith CB, White DB, Chu E, Tiver GA, Einhorn S, Arnold RM. PMID: 24301842; PMCID: PMC3948709.
      View in: PubMed   Mentions: 75     Fields:    Translation:Humans
    89. Calcium carbonate does not affect imatinib pharmacokinetics in healthy volunteers. Cancer Chemother Pharmacol. 2014 Jan; 73(1):207-11. Tawbi H, Christner SM, Lin Y, Johnson M, Mowrey ET, Cherrin C, Chu E, Lee JJ, Puhalla S, Stoller R, Appleman LR, Miller BM, Beumer JH. PMID: 24170263; PMCID: PMC3880632.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    90. Comparing EPI-743 treatment in siblings with Leber's hereditary optic neuropathy mt14484 mutation. Can J Ophthalmol. 2013 Oct; 48(5):e130-3. Chicani CF, Chu ER, Miller G, Kelman SE, Sadun AA. PMID: 24093206.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    91. The use of multidetector computed tomography in lower gastrointestinal bleeding. Am Surg. 2013 Sep; 79(9):953-5. Chu EW, Harrington AN, Divino CM. PMID: 24069998.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    92. Smooth muscle features of mouse extraocular muscle. Clin Exp Ophthalmol. 2014 Apr; 42(3):295-6. Ko MK, Chu ER, Tan JCh. PMID: 23848483; PMCID: PMC4078399.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    93. An illustrative case that demonstrates the importance of neuroimaging in midbrain corectopia. Can J Ophthalmol. 2013 Aug; 48(4):e76-8. Chu ER, Sadun AA. PMID: 23931488.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    94. Intraocular pressure measurement in acepromazine-sedated mice. Clin Exp Ophthalmol. 2014 May-Jun; 42(4):395-7. Chu ER, Kim EK, Gonzalez JM, Ko MH, Liew EC, Tan JC. PMID: 23777364.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    95. LC-MS/MS assay for the quantitation of the HDAC inhibitor belinostat and five major metabolites in human plasma. J Pharm Biomed Anal. 2013 Jul-Aug; 81-82:89-98. Kiesel BF, Parise RA, Tjørnelund J, Christensen MK, Loza E, Tawbi H, Chu E, Kummar S, Beumer JH. PMID: 23644904; PMCID: PMC3663884.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    96. Neuro-ophthalmology Safer Than MRI? Ophthalmology. 2013 Apr; 120(4):879. Sadun AA, Chu ER, Boisvert CJ. PMID: 23552093.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    97. Serum markers for predicting abdominal surgery outcomes in patients with cirrhosis. J Gastrointest Surg. 2013 Apr; 17(4):696-701. Harrington AN, Chu EW, Garg M, Divino CM. PMID: 23400508.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    98. The surgical management of active ulcerative colitis complicated by Clostridium difficile infection. J Gastrointest Surg. 2013 Feb; 17(2):392-6. Chu EW, Ecker BL, Garg M, Divino CM. PMID: 23135837.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    99. Liver fibrosis in elderly cadavers: localization of collagen types I, III, and IV, α-smooth muscle actin, and elastic fibers. Anat Rec (Hoboken). 2012 Jul; 295(7):1159-67. Mak KM, Chu E, Lau KH, Kwong AJ. PMID: 22644959.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    100. Hepatic steatosis, fibrosis, and cancer in elderly cadavers. Anat Rec (Hoboken). 2012 Jan; 295(1):40-50. Mak KM, Kwong AJ, Chu E, Hoo NM. PMID: 22139908.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    101. An update on the current and emerging targeted agents in metastatic colorectal cancer. Clin Colorectal Cancer. 2012 Mar; 11(1):1-13. Chu E. PMID: 21752724.
      View in: PubMed   Mentions: 77     Fields:    Translation:Humans
    102. Cessation of clopidogrel before major abdominal procedures. Arch Surg. 2011 Mar; 146(3):334-9. Chernoguz A, Telem DA, Chu E, Ozao-Choy J, Tammaro Y, Divino CM. PMID: 21422366.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    103. Concurrent central retinal artery occlusion and branch retinal vein occlusion in giant cell arteritis. Clin Ophthalmol. 2010 Jul 21; 4:565-7. Chu ER, Chen CS. PMID: 20668717; PMCID: PMC2909884.
      View in: PubMed   Mentions: 1  
    104. Another case of congenital pupillary-iris-lens membrane with goniodysgenesis. J Pediatr Ophthalmol Strabismus. 2010 May 21; 47 Online:e1-3. Chu ER, Taranath DA. PMID: 21214149.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    105. Biology of colorectal cancer. Cancer J. 2010 May-Jun; 16(3):196-201. Saif MW, Chu E. PMID: 20526096.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    106. Venom ophthalmia caused by venoms of spitting elapid and other snakes: Report of ten cases with review of epidemiology, clinical features, pathophysiology and management. Toxicon. 2010 Sep 01; 56(3):259-72. Chu ER, Weinstein SA, White J, Warrell DA. PMID: 20331993.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    107. Is there any role for intravenous antivenom for snake venom ophthalmia? J Emerg Med. 2010 Nov; 39(5):659-60; author reply 660-1. Chu ER, White J, Weinstein S. PMID: 20005661.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    108. Terson Syndrome from a Significant Cerebral Infarct Occurring During the Peripartum Period. J Pediatr Ophthalmol Strabismus. 2009 Nov 02. Chu ER, Sandinha T, Lake S, Pater J. PMID: 19873953.
      View in: PubMed   Mentions:    Fields:    
    109. Optic neuritis--more than a loss of vision. Aust Fam Physician. 2009 Oct; 38(10):789-93. Chu ER, Chen CS. PMID: 19893818.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    110. Nineteen-year delayed-onset phacolytic uveitis following dislocation of the crystalline lens. Can J Ophthalmol. 2009 Feb; 44(1):112. Chu ER, Durkin SR, Keembiyage RD, Nathan F, Raymond G. PMID: 19169334.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    111. Treatment of metastatic colorectal cancer: from cytotoxic agents to molecular agents and multitargeted strategies. Oncology (Williston Park). 2006 Dec; 20(14 Suppl 10):11-9. Saif MW, Kang SP, Chu E. PMID: 17354513.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
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