Gary Humfleet, PhD

Title(s)Professor, Psychiatry
SchoolSchool of Medicine
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    I am a clinical psychologist and Professor in the Department of Psychiatry at the University of California, San Francisco. In this role I am involved in clinical, research, and training activities. My clinical interests are in individual and group treatment for a variety of mental health issues, including anxiety, depression and addiction. I have extensive experience and expertise in brief treatment and long-term treatment models including cognitive-behavioral, motivational interviewing/enhancement, problem-solving, relaxation training, and 12-step interventions. My clinical and research interests include addressing health and mental health disparities among low-income populations, the LGBT community, and individuals impacted by HIV as well as integrating digital interventions into treatment.

    My research focuses on the evaluation of clinical interventions for nicotine dependence, factors predictive of smoking treatment success, and development of Internet-based interventions for health behavior change. Much of my research focuses on populations experiencing tobacco-related health disparities including LGBT individuals, individuals with HIV disease, smokers with drug dependence, and low-income groups. I have conducted clinical trials evaluating the efficacy of internet-based and telephone-based smoking treatment for LGBT cigarette smokers. I recently led a study evaluating the efficacy and cost-effectiveness of smoking cessation treatment provided in HIV clinical care settings. Other work has focused on interventions with depressed smokers and the development of an extended smoking treatment model based on the conceptualization of nicotine dependence as a chronic, relapsing disorder.

    Collapse Research 
    Collapse Research Activities and Funding
    LGBT Internet Based Smoking Treatment
    NIH/NIDA R01DA015791Sep 30, 2002 - May 31, 2007
    Role: Principal Investigator
    Treatment for Complex Patients: Continuing and Extended Care
    NIH/NIDA P50DA009253Sep 29, 1994 - May 31, 2015
    Role: Co-Investigator
    Maintaining Nonsmoking
    NIH/NIDA R01DA002538Apr 1, 1980 - May 31, 2014
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Vogel EA, Humfleet GL, Meacham M, Prochaska JJ, Ramo DE. Sexual and gender minority young adults' smoking characteristics: Assessing differences by sexual orientation and gender identity. Addict Behav. 2019 Mar 05; 95:98-102. PMID: 30875534.
      View in: PubMed
    2. Ramo DE, Meacham M, Thrul J, Belohlavek A, Sarkar U, Humfleet G. Exploring Identities and Preferences for Intervention Among LGBTQ+ Young Adult Smokers Through Online Focus Groups. J Adolesc Health. 2018 Nov 30. PMID: 30509769.
      View in: PubMed
    3. Vogel EA, Thrul J, Humfleet GL, Delucchi KL, Ramo DE. Smoking cessation intervention trial outcomes for sexual and gender minority young adults. Health Psychol. 2019 Jan; 38(1):12-20. PMID: 30489104.
      View in: PubMed
    4. Hall SM, Humfleet GL, Gasper JJ, Delucchi KL, Hersh DF, Guydish JR. Cigarette Smoking Cessation Intervention for Buprenorphine Treatment Patients. Nicotine Tob Res. 2018 Apr 02; 20(5):628-635. PMID: 28549161.
      View in: PubMed
    5. Gubner NR, Guydish J, Humfleet GL, Benowitz NL, Hall SM. Nicotine biomarkers and rate of nicotine metabolism among cigarette smokers taking buprenorphine for opioid dependency. Drug Alcohol Depend. 2017 09 01; 178:267-270. PMID: 28683421.
      View in: PubMed
    6. Hall SM, Shi Y, Humfleet GL, Muñoz RF, Reus VI, Prochaska JJ. Smoking cessation abstinence goal in treatment-seeking smokers. Addict Behav. 2015 Mar; 42:148-53. PMID: 25462664; PMCID: PMC4273741.
    7. Grady ES, Humfleet GL, Delucchi KL, Reus VI, Muñoz RF, Hall SM. Smoking cessation outcomes among sexual and gender minority and nonminority smokers in extended smoking treatments. Nicotine Tob Res. 2014 Sep; 16(9):1207-15. PMID: 24727483; PMCID: PMC4155474.
    8. Barnett PG, Wong W, Jeffers A, Munoz R, Humfleet G, Hall S. Cost-effectiveness of extended cessation treatment for older smokers. Addiction. 2014 Feb; 109(2):314-22. PMID: 24329972; PMCID: PMC4020783.
    9. Lisha NE, Carmody TP, Humfleet GL, Delucchi KL. Reciprocal effects of alcohol and nicotine in smoking cessation treatment studies. Addict Behav. 2014 Mar; 39(3):637-43. PMID: 24333039; PMCID: PMC3906916.
    10. Humfleet GL, Hall SM, Delucchi KL, Dilley JW. A randomized clinical trial of smoking cessation treatments provided in HIV clinical care settings. Nicotine Tob Res. 2013 Aug; 15(8):1436-45. PMID: 23430708.
      View in: PubMed
    11. Hendricks PS, Delucchi KL, Humfleet GL, Hall SM. Alcohol and marijuana use in the context of tobacco dependence treatment: impact on outcome and mediation of effect. Nicotine Tob Res. 2012 Aug; 14(8):942-51. PMID: 22259148; PMCID: PMC3439865.
    12. Hall SM, Humfleet GL, Muñoz RF, Reus VI, Prochaska JJ, Robbins JA. Using extended cognitive behavioral treatment and medication to treat dependent smokers. Am J Public Health. 2011 Dec; 101(12):2349-56. PMID: 21653904; PMCID: PMC3222443.
    13. Lawhon D, Humfleet GL, Hall SM, Muñoz RF, Reus VI. Longitudinal analysis of abstinence-specific social support and smoking cessation. Health Psychol. 2009 Jul; 28(4):465-72. PMID: 19594271.
      View in: PubMed
    14. Humfleet GL, Delucchi K, Kelley K, Hall SM, Dilley J, Harrison G. Characteristics of HIV-positive cigarette smokers: a sample of smokers facing multiple challenges. AIDS Educ Prev. 2009 Jun; 21(3 Suppl):54-64. PMID: 19537954; PMCID: PMC2752468.
    15. Hall SM, Humfleet GL, Muñoz RF, Reus VI, Robbins JA, Prochaska JJ. Extended treatment of older cigarette smokers. Addiction. 2009 Jun; 104(6):1043-52. PMID: 19392908; PMCID: PMC2718733.
    16. Hendricks PS, Prochaska JJ, Humfleet GL, Hall SM. Evaluating the validities of different DSM-IV-based conceptual constructs of tobacco dependence. Addiction. 2008 Jul; 103(7):1215-23. PMID: 18554351; PMCID: PMC2744341.
    17. Prochaska JJ, Hall SM, Humfleet G, Munoz RF, Reus V, Gorecki J, Hu D. Physical activity as a strategy for maintaining tobacco abstinence: a randomized trial. Prev Med. 2008 Aug; 47(2):215-20. PMID: 18572233; PMCID: PMC2536696.
    18. Hall SM, Humfleet GL, Gorecki JA, Muñoz RF, Reus VI, Prochaska JJ. Older versus younger treatment-seeking smokers: differences in smoking behavior, drug and alcohol use, and psychosocial and physical functioning. Nicotine Tob Res. 2008 Mar; 10(3):463-70. PMID: 18324565; PMCID: PMC3247917.
    19. Mooney ME, Reus VI, Gorecki J, Hall SM, Humfleet GL, Muñoz RF, Delucchi K. Therapeutic drug monitoring of nortriptyline in smoking cessation: a multistudy analysis. Clin Pharmacol Ther. 2008 Mar; 83(3):436-42. PMID: 17687275; PMCID: PMC2700120.
    20. Prochaska JJ, Hall SM, Tsoh JY, Eisendrath S, Rossi JS, Redding CA, Rosen AB, Meisner M, Humfleet GL, Gorecki JA. Treating tobacco dependence in clinically depressed smokers: effect of smoking cessation on mental health functioning. Am J Public Health. 2008 Mar; 98(3):446-8. PMID: 17600251; PMCID: PMC2253568.
    21. Hall SM, Gorecki JA, Reus VI, Humfleet GL, Muñoz RF. Belief about drug assignment and abstinence in treatment of cigarette smoking using nortriptyline. Nicotine Tob Res. 2007 Apr; 9(4):467-71. PMID: 17454701.
      View in: PubMed
    22. Hall SM, Tsoh JY, Prochaska JJ, Eisendrath S, Rossi JS, Redding CA, Rosen AB, Meisner M, Humfleet GL, Gorecki JA. Treatment for cigarette smoking among depressed mental health outpatients: a randomized clinical trial. Am J Public Health. 2006 Oct; 96(10):1808-14. PMID: 17008577; PMCID: PMC1586139.
    23. Hall SM, Lightwood JM, Humfleet GL, Bostrom A, Reus VI, Muñoz R. Cost-effectiveness of bupropion, nortriptyline, and psychological intervention in smoking cessation. J Behav Health Serv Res. 2005 Oct-Dec; 32(4):381-92. PMID: 16215448.
      View in: PubMed
    24. Humfleet GL, Prochaska JJ, Mengis M, Cullen J, Muñoz R, Reus V, Hall SM. Preliminary evidence of the association between the history of childhood attention-deficit/hyperactivity disorder and smoking treatment failure. Nicotine Tob Res. 2005 Jun; 7(3):453-60. PMID: 16085513.
      View in: PubMed
    25. Haug NA, Hall SM, Prochaska JJ, Rosen AB, Tsoh JY, Humfleet G, Delucchi K, Rossi JS, Redding CA, Eisendrath S. Acceptance of nicotine dependence treatment among currently depressed smokers. Nicotine Tob Res. 2005 Apr; 7(2):217-24. PMID: 16036278.
      View in: PubMed
    26. Greenwood GL, Paul JP, Pollack LM, Binson D, Catania JA, Chang J, Humfleet G, Stall R. Tobacco use and cessation among a household-based sample of US urban men who have sex with men. Am J Public Health. 2005 Jan; 95(1):145-51. PMID: 15623875; PMCID: PMC1449867.
    27. Prochaska JJ, Rossi JS, Redding CA, Rosen AB, Tsoh JY, Humfleet GL, Eisendrath SJ, Meisner MR, Hall SM. Depressed smokers and stage of change: implications for treatment interventions. Drug Alcohol Depend. 2004 Nov 11; 76(2):143-51. PMID: 15488338.
      View in: PubMed
    28. Hall SM, Humfleet GL, Reus VI, Muñoz RF, Cullen J. Extended nortriptyline and psychological treatment for cigarette smoking. Am J Psychiatry. 2004 Nov; 161(11):2100-7. PMID: 15514412.
      View in: PubMed
    29. Haas AL, Muñoz RF, Humfleet GL, Reus VI, Hall SM. Influences of mood, depression history, and treatment modality on outcomes in smoking cessation. J Consult Clin Psychol. 2004 Aug; 72(4):563-70. PMID: 15301640.
      View in: PubMed
    30. Humfleet GL, Haas AL. Is marijuana use becoming a 'gateway' to nicotine dependence? Addiction. 2004 Jan; 99(1):5-6. PMID: 14678052.
      View in: PubMed
    31. Hall SM, Humfleet GL, Reus VI, Muñoz RF, Hartz DT, Maude-Griffin R. Psychological intervention and antidepressant treatment in smoking cessation. Arch Gen Psychiatry. 2002 Oct; 59(10):930-6. PMID: 12365880.
      View in: PubMed
    32. Tsoh JY, Humfleet GL, Muñoz RF, Reus VI, Hartz DT, Hall SM. Development of major depression after treatment for smoking cessation. Am J Psychiatry. 2000 Mar; 157(3):368-74. PMID: 10698811.
      View in: PubMed
    33. Humfleet G, Muñoz R, Sees K, Reus V, Hall S. History of alcohol or drug problems, current use of alcohol or marijuana, and success in quitting smoking. Addict Behav. 1999 Jan-Feb; 24(1):149-54. PMID: 10189984.
      View in: PubMed
    34. Maude-Griffin PM, Hohenstein JM, Humfleet GL, Reilly PM, Tusel DJ, Hall SM. Superior efficacy of cognitive-behavioral therapy for urban crack cocaine abusers: main and matching effects. J Consult Clin Psychol. 1998 Oct; 66(5):832-7. PMID: 9803702.
      View in: PubMed
    35. Hall SM, Reus VI, Muñoz RF, Sees KL, Humfleet G, Hartz DT, Frederick S, Triffleman E. Nortriptyline and cognitive-behavioral therapy in the treatment of cigarette smoking. Arch Gen Psychiatry. 1998 Aug; 55(8):683-90. PMID: 9707377.
      View in: PubMed
    36. Hall SM, Muñoz RF, Reus VI, Sees KL, Duncan C, Humfleet GL, Hartz DT. Mood management and nicotine gum in smoking treatment: a therapeutic contact and placebo-controlled study. J Consult Clin Psychol. 1996 Oct; 64(5):1003-9. PMID: 8916629.
      View in: PubMed
    37. Fitzgibbon ML, Cella DF, Humfleet G, Griffin E, Sheridan K. Motor slowing in asymptomatic HIV infection. Percept Mot Skills. 1989 Jun; 68(3 Pt 2):1331-8. PMID: 2762096.
      View in: PubMed