Neal Benowitz, MD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address1001 Potrero Avenue, #2703
San Francisco CA
Phone415-502-1034
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency School of Medicine - Internal Medicine

    Collapse Overview 
    Collapse Overview
    Neal Benowitz has been involved in patient care and conducting research at SFGH since 1973. His research focus is on the human pharmacology of nicotine in relation to pathogenesis of and individual differences in vulnerability to tobacco-related disease, and the use of pharmacologic data as a basis for public health policies to prevent and reduce such disease. He has also studied the human pharmacolgy and toxicology of cannabis products. He has served on a number of national and international committees addressing issues in tobacco-related diseases and smoking cessation, including several sponsored by the Institute of Medicine. He has served as president of the American Society for Clinical Pharmacology and Therapeutics and the Society for Research on Nicotine and Tobacco. He has authored over 700 publications, including a state-of-the-art review on nicotine addiction in the New England Journal of Medicine in June 2010. He maintains an active clinical practice in cardiology and medical toxicology

    Collapse Research 
    Collapse Research Activities and Funding
    Cigarette Harm Reduction with Scheduled Electronic Cigarette Use
    NIH U01DA045519Aug 15, 2018 - Jul 31, 2022
    Role: Principal Investigator
    Clinical Pharmacology of Electronic Cigarettes
    NIH R01DA039264Jun 1, 2015 - Jun 30, 2022
    Role: Principal Investigator
    Technology Innovations for Supporting Health in Alaska Native People
    NIH R01HL117736Apr 1, 2013 - Mar 31, 2021
    Role: Co-Principal Investigator
    Mechanisms of the Nicotine Metabolism Effect on Tobacco Dependence
    NIH R01DA031193May 1, 2012 - Mar 31, 2016
    Role: Principal Investigator
    Pharmacogenetics of Nicotine Addiction Treatment
    NIH U01DA020830Sep 15, 2005 - Jun 30, 2016
    Role: Co-Principal Investigator
    Drug Dependence Clinical Research Program
    NIH P30DA012393Sep 1, 1999 - May 31, 2025
    Role: Co-Principal Investigator
    Cancer Center Support Grant
    NIH P30CA082103Aug 5, 1999 - May 31, 2023
    Role: Co-Investigator
    Safety of Nicotine Reduction Strategy
    NIH R01CA078603Jun 1, 1999 - Nov 30, 2010
    Role: Principal Investigator
    NICOTINE METABOLISM IN PREGNANCY
    NIH R01DA009761Jul 1, 1995 - Jun 30, 1998
    Role: Principal Investigator
    PHARMACOLOGY OF NICOTINE IN HUMAN CARDIOVASCULAR DISEASE
    NIH R01HL029476Sep 1, 1982 - Aug 31, 1986
    Role: Principal Investigator
    NICOTINE AND TAR INTAKE DURING CIGARETTE SMOKING
    NIH R01CA032389Jul 1, 1982 - Jun 30, 1990
    Role: Principal Investigator
    Pharmacokinetics and Pharmacodynamics of Nicotine
    NIH R01DA002277Mar 1, 1979 - Jun 30, 2014
    Role: Principal Investigator
    PHARMACOKINETICS AND PHARMACODYNAMICS OF NICOTINE
    NIH R37DA002277Mar 1, 1979 - Jun 30, 2003
    Role: Principal Investigator
    DRUG DEPENDENCE CLINICAL RESEARCH PROGRAM
    NIH P50DA001696Feb 1, 1978 - Aug 31, 2000
    Role: Co-Investigator
    Clinical Pharmacology, Drug Action and Pharmacogenetics
    NIH T32GM007546Jul 1, 1977 - Jun 30, 2025
    Role: Co-Principal Investigator
    General Clinical Research Center
    NIH M01RR000083Oct 1, 1974 - Nov 30, 2007
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Collaboration Interests

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Pharmacokinetics and pharmacodynamics of inhaled nicotine salt and free-base using an e-cigarette: A randomized crossover study. Nicotine Tob Res. 2024 Apr 10. Christen SE, Hermann L, Bekka E, Vonwyl C, Hammann F, van der Velpen V, Eap CB, Benowitz NL, Haschke M, Liakoni E. PMID: 38597729.
      View in: PubMed   Mentions:
    2. Tobacco Constituents, Flavorants, and Paper Permeability of Factory-Made and Roll-Your-Own Cigarettes on the Australian Market. Nicotine Tob Res. 2024 Feb 22; 26(3):289-297. Haynes A, Winnall WR, Brennan E, Dunstone K, Benowitz NL, Ashley DL, Samet JM, Hatsukami DK, Wakefield MA. PMID: 37462724.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Society for Research on Nicotine and Tobacco as an Outgrowth of the 1988 Surgeon General's Report on Nicotine Addiction: Reflections of the Early Presidents. Nicotine Tob Res. 2024 Jan 22; 26(2):118-125. Pomerleau OF, Benowitz NL, Stitzer ML, Henningfield JE, Hatsukami DK, Corrigall WA, Perkins KA, Lando HA. PMID: 37584666; PMCID: PMC10803119.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Electronic hookah (waterpipe) vaping reduces vascular endothelial function: the role of nicotine. Am J Physiol Heart Circ Physiol. 2024 Mar 01; 326(3):H490-H496. Rezk-Hanna M, Rossman MJ, Ludwig K, Sakti P, Cheng CW, Brecht ML, Benowitz NL, Seals DR. PMID: 38133618.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Nicotine delivery and changes in withdrawal and craving during acute electronic cigarette, heated tobacco product, and cigarette use among a sample of Black and White people who smoke. Nicotine Tob Res. 2023 Dec 14. Leavens ELS, Lambart L, Diaz FJ, Wagener TL, Ahluwalia JS, Benowitz N, Nollen NL. PMID: 38097340.
      View in: PubMed   Mentions:    Fields:    
    6. Association of non-daily hookah tobacco smoking and cardiovascular disease-related exposure biomarkers among U.S. users: The Population Assessment of Tobacco and Health Study. Prev Med Rep. 2023 Dec; 36:102417. Rezk-Hanna M, Adolfo A, Warda US, Brecht ML, Benowitz NL. PMID: 37753385; PMCID: PMC10518337.
      View in: PubMed   Mentions:
    7. Biomarkers of Toxic Exposure and Oxidative Stress Among U.S. Adult Users of Premium Cigar Versus Other Cigar Subtypes: 2013-2019. Nicotine Tob Res. 2023 07 28; 25(Suppl_1):S84-S93. Dai HD, Benowitz NL, Rogan E, Degarege A, Buckley J, Khan AS. PMID: 37506235; PMCID: PMC10381103.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Nicotine Intake in Adult Pod E-cigarette Users: Impact of User and Device Characteristics. Nicotine Tob Res. 2023 Jul 14; 25(8):1489-1495. Giberson J, Nardone N, Addo N, Khan S, Jacob P, Benowitz N, St Helen G. PMID: 37061820; PMCID: PMC10347964.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Cytisinicline for Smoking Cessation: A Randomized Clinical Trial. JAMA. 2023 07 11; 330(2):152-160. Rigotti NA, Benowitz NL, Prochaska J, Leischow S, Nides M, Blumenstein B, Clarke A, Cain D, Jacobs C. PMID: 37432430; PMCID: PMC10336611.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Policy-relevant differences between secondhand and thirdhand smoke: strengthening protections from involuntary exposure to tobacco smoke pollutants. Tob Control. 2023 Jun 01. Matt GE, Greiner L, Record RA, Wipfli H, Long J, Dodder NG, Hoh E, Lopez Galvez N, Novotny TE, Quintana PJE, Destaillats H, Tang X, Snijders AM, Mao JH, Hang B, Schick S, Jacob P, Talbot P, Mahabee-Gittens EM, Merianos AL, Northrup TF, Gundel L, Benowitz NL. PMID: 37263783.
      View in: PubMed   Mentions: 1     Fields:    
    11. Effects of dual use of e-cigarette and cannabis during adolescence on cigarette use in young adulthood. Tob Control. 2023 May 05. Islam T, Eckel S, Liu F, Barrington-Trimis J, Harlow AF, Benowitz N, Leventhal A, McConnell R, Cho J. PMID: 37147126.
      View in: PubMed   Mentions: 2     Fields:    
    12. How the FDA Can Improve Public Health - Helping People Stop Smoking. N Engl J Med. 2023 Apr 27; 388(17):1540-1542. Benowitz NL, Warner KE, Myers ML, Hatsukami D, Berman ML, Vallone D, Cohen JE. PMID: 37092791.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    13. A Phase I, Double-blind, Randomized, Placebo-controlled, Single Dose-escalation Study to Evaluate the Tolerability, and Safety of Cytisinicline in Adult Smokers. Nicotine Tob Res. 2023 03 22; 25(4):814-820. Jacobs C, Fonseca M, Rigotti NA, Benowitz N, Clarke A, Cain D. PMID: 36198104.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    14. Thirdhand tobacco smoke exposure increases the genetic background-dependent risk of pan-tumor development in Collaborative Cross mice. Environ Int. 2023 04; 174:107876. Yang H, Wang X, Wang P, He L, Schick SF, Jacob P, Benowitz N, Gundel LA, Zhu C, Xia Y, Inman JL, Chang H, Snijders AM, Mao JH, Hang B. PMID: 36940581.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsPHPublic Health
    15. Nicotine e-cigarettes as a tool for smoking cessation. Nat Med. 2023 03; 29(3):520-524. Warner KE, Benowitz NL, McNeill A, Rigotti NA. PMID: 36788367.
      View in: PubMed   Mentions: 6     Fields:    
    16. A critique of the Australian National Health and Medical Research Council CEO statement on electronic cigarettes. Addiction. 2023 06; 118(6):1184-1192. Mendelsohn CP, Hall W, Borland R, Wodak A, Beaglehole R, Benowitz NL, Britton J, Bullen C, Etter JF, McNeill A, Rigotti NA. PMID: 36808672.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    17. Associations of Demographics, Dependence, and Biomarkers With Transitions in Tobacco Product Use in a Cohort of Cigarette Users and Dual Users of Cigarettes and E-cigarettes. Nicotine Tob Res. 2023 02 09; 25(3):462-469. Shafie-Khorassani F, Piper ME, Jorenby DE, Baker TB, Benowitz NL, Hayes-Birchler T, Meza R, Brouwer AF. PMID: 36037523; PMCID: PMC9910158.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. The E-cigarette or Vaping Product Use-Associated Lung Injury Epidemic: Pathogenesis, Management, and Future Directions: An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2023 01; 20(1):1-17. Rebuli ME, Rose JJ, Noël A, Croft DP, Benowitz NL, Cohen AH, Goniewicz ML, Larsen BT, Leigh N, McGraw MD, Melzer AC, Penn AL, Rahman I, Upson D, Crotty Alexander LE, Ewart G, Jaspers I, Jordt SE, Kligerman S, Loughlin CE, McConnell R, Neptune ER, Nguyen TB, Pinkerton KE, Witek TJ. PMID: 36584985; PMCID: PMC9819258.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansPHPublic Health
    19. Vaping THC-O Acetate: Potential for Another EVALI Epidemic. J Med Toxicol. 2023 01; 19(1):37-39. Benowitz NL, Havel C, Jacob P, O'Shea DF, Wu D, Fowles J. PMID: 36508081; PMCID: PMC9813278.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    20. Caffeine levels and dietary intake in smokers with schizophrenia and bipolar disorder. Psychiatry Res. 2023 01; 319:114989. Rosen RL, Ramasubramani RS, Benowitz NL, Gandhi KK, Williams JM. PMID: 36470161.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Lifetime use of non-nicotine drugs in electronic cigarette devices among a sample of individuals in substance use disorder treatment. Addict Behav Rep. 2022 Dec; 16:100465. Masson CL, Gubner NR, Benowitz N, Hosakote S, Le T, Guydish JR. PMID: 36341309; PMCID: PMC9633988.
      View in: PubMed   Mentions: 1  
    22. Early Changes in Puffing Intensity When Exclusively Using Open-Label Very Low Nicotine Content Cigarettes. Nicotine Tob Res. 2022 10 26; 24(11):1798-1802. White CM, Watson C, Bravo Cardenas R, Ngac P, Valentin-Blasini L, Blount BC, Koopmeiners JS, Denlinger-Apte RL, Pacek LR, Benowitz NL, Hatsukami DK, Donny EC, Carpenter MJ, Smith TT. PMID: 35524988; PMCID: PMC9597006.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Association of cannabis use during pregnancy with severe acute respiratory syndrome coronavirus 2 infection: a retrospective cohort study. Addiction. 2023 02; 118(2):317-326. Young-Wolff KC, Ray GT, Alexeeff SE, Benowitz N, Adams SR, Does MB, Goler N, Ansley D, Conway A, Avalos LA. PMID: 36189777; PMCID: PMC9812868.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    24. Demographic and cultural correlates of traditional eating among Alaska Native adults at risk for cardiovascular disease. PLoS One. 2022; 17(9):e0275445. Sanders MA, Oppezzo M, Skan J, Benowitz NL, Schnellbaecher M, Prochaska JJ. PMID: 36178914; PMCID: PMC9524684.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    25. The Effect of Tobacco Use on the Expression of Placental Transporters in Alaska Native Women. Clin Pharmacol Ther. 2023 03; 113(3):634-642. McColl ER, Kwok J, Benowitz NL, Patten CA, Hughes CA, Koller KR, Flanagan CA, Thomas TK, Hiratsuka VY, Tyndale RF, Piquette-Miller M. PMID: 36053152; PMCID: PMC10234256.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. Tobacco product use and the risks of SARS-CoV-2 infection and COVID-19: current understanding and recommendations for future research. Lancet Respir Med. 2022 09; 10(9):900-915. Benowitz NL, Goniewicz ML, Halpern-Felsher B, Krishnan-Sarin S, Ling PM, O'Connor RJ, Pentz MA, Robertson RM, Bhatnagar A. PMID: 35985357; PMCID: PMC9381032.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCellsPHPublic Health
    27. Traditional Heart-Healthy Diet and Medication Adherence in the Norton Sound Region: An 18-Month Telehealth Intervention. Int J Environ Res Public Health. 2022 08 11; 19(16). Oppezzo M, Knox M, Skan J, Chieng A, Crouch M, Aikens RC, Benowitz NL, Schnellbaecher M, Prochaska JJ. PMID: 36011519; PMCID: PMC9408057.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    28. Thirdhand Exposures to Tobacco-Specific Nitrosamines through Inhalation, Dust Ingestion, Dermal Uptake, and Epidermal Chemistry. Environ Sci Technol. 2022 09 06; 56(17):12506-12516. Tang X, Benowitz N, Gundel L, Hang B, Havel CM, Hoh E, Jacob Iii P, Mao JH, Martins-Green M, Matt GE, Quintana PJE, Russell ML, Sarker A, Schick SF, Snijders AM, Destaillats H. PMID: 35900278.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    29. Smoking abstinence and cessation-related outcomes one month after an immediate versus gradual reduction in nicotine content of cigarettes. Prev Med. 2022 12; 165(Pt B):107175. Klemperer EM, Luo X, Jensen J, al'Absi M, Cinciripini PM, Robinson JD, Drobes DJ, McClernon J, Strasser AA, Strayer LG, Vandrey R, Benowitz NL, Donny EC, Hatsukami DK. PMID: 35870575; PMCID: PMC10676511.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. Effects of Marijuana Use on Smokers Switching to E-Cigarettes in a Randomized Clinical Trial. Nicotine Tob Res. 2022 06 15; 24(7):994-1002. Rice M, Nollen NL, Ahluwalia JS, Benowitz N, Woodcock A, Pulvers K. PMID: 35022796; PMCID: PMC9199934.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    31. Associations of Smokeless Tobacco Use With Cardiovascular Disease Risk: Insights From the Population Assessment of Tobacco and Health Study. Nicotine Tob Res. 2022 06 15; 24(7):1063-1070. Rezk-Hanna M, Warda US, Stokes AC, Fetterman J, Li J, Macey PM, Darawad M, Song Y, Ben Taleb Z, Brecht ML, Benowitz NL. PMID: 34999825; PMCID: PMC9199939.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. Effect of Varenicline Added to Counseling on Smoking Cessation Among African American Daily Smokers: The Kick It at Swope IV Randomized Clinical Trial. JAMA. 2022 06 14; 327(22):2201-2209. Cox LS, Nollen NL, Mayo MS, Faseru B, Greiner A, Ellerbeck EF, Krebill R, Tyndale RF, Benowitz NL, Ahluwalia JS. PMID: 35699705; PMCID: PMC9198729.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    33. Minor Tobacco Alkaloids as Biomarkers to Distinguish Combusted Tobacco Use From Electronic Nicotine Delivery Systems Use. Two New Analytical Methods. Front Chem. 2022; 10:749089. Jacob P, Chan L, Cheung P, Bello K, Yu L, StHelen G, Benowitz NL. PMID: 35720984; PMCID: PMC9198481.
      View in: PubMed   Mentions: 1  
    34. Cigarette Smoke Exposure and Acute Respiratory Distress Syndrome in Sepsis: Epidemiology, Clinical Features, and Biologic Markers. Am J Respir Crit Care Med. 2022 04 15; 205(8):927-935. Moazed F, Hendrickson C, Jauregui A, Gotts J, Conroy A, Delucchi K, Zhuo H, Arambulo M, Vessel K, Ke S, Deiss T, Ni A, Leligdowicz A, Abbott J, Cohen MJ, Sinha P, Gomez A, Kangelaris K, Kornblith L, Matthay M, Benowitz N, Liu K, Calfee CS. PMID: 35050845; PMCID: PMC9838633.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    35. The Central Role of pH in the Clinical Pharmacology of Nicotine: Implications for Abuse Liability, Cigarette Harm Reduction and FDA Regulation. Clin Pharmacol Ther. 2022 05; 111(5):1004-1006. Benowitz NL. PMID: 35220591; PMCID: PMC9035094.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    36. Tobacco-specific and combustion pollutants in settled house dust in Malta. J Environ Expo Assess. 2022; 1. Aquilina NJ, Havel CM, Benowitz NL, Jacob P. PMID: 35497707; PMCID: PMC9056077.
      View in: PubMed   Mentions: 1  
    37. Maternal nicotine metabolism moderates the impact of maternal cigarette smoking on infant birth weight: A Collaborative Perinatal Project investigation. Drug Alcohol Depend. 2022 04 01; 233:109358. Stroud LR, Papandonatos GD, Jao NC, Niaura R, Buka S, Benowitz NL. PMID: 35247723; PMCID: PMC8977115.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    38. Exposure to Toxicants Associated With Use and Transitions Between Cigarettes, e-Cigarettes, and No Tobacco. JAMA Netw Open. 2022 02 01; 5(2):e2147891. Dai H, Benowitz NL, Achutan C, Farazi PA, Degarege A, Khan AS. PMID: 35142830; PMCID: PMC8832174.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansPHPublic Health
    39. Balfour et al. Respond. Am J Public Health. 2022 01; 112(1):e5-e6. Balfour DJK, Benowitz NL, Colby SM, Hatsukami DK, Lando HA, Leischow SJ, Lerman C, Mermelstein RJ, Niaura R, Perkins KA, Pomerleau OF, Rigotti NA, Swan GE, Warner KE, West R. PMID: 34936414; PMCID: PMC8713597.
      View in: PubMed   Mentions:    Fields:    
    40. Balfour et al. Respond. Am J Public Health. 2022 01; 112(1):e2-e3. Balfour DJK, Benowitz NL, Colby SM, Hatsukami DK, Lando HA, Leischow SJ, Lerman C, Mermelstein RJ, Niaura R, Perkins KA, Pomerleau OF, Rigotti NA, Swan GE, Warner KE, West R. PMID: 34936419; PMCID: PMC8713616.
      View in: PubMed   Mentions: 1     Fields:    
    41. Reappraising Choice in Addiction: Novel Conceptualizations and Treatments for Tobacco Use Disorder. Nicotine Tob Res. 2022 01 01; 24(1):3-9. Palmer AM, Toll BA, Carpenter MJ, Donny EC, Hatsukami DK, Rojewski AM, Smith TT, Sofuoglu M, Thrul J, Benowitz NL. PMID: 34270729; PMCID: PMC8666123.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    42. Tobacco-free Nicotine - New Name, Same Scheme? N Engl J Med. 2021 Dec 23; 385(26):2406-2408. Cwalina SN, McConnell R, Benowitz NL, Barrington-Trimis JL. PMID: 34919358; PMCID: PMC9153389.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    43. Does sex alter the relationship between CYP2B6 variation, hydroxybupropion concentration and bupropion-aided smoking cessation in African Americans? A moderated mediation analysis. Addiction. 2022 06; 117(6):1715-1724. Chenoweth MJ, Peng AR, Zhu AZX, Cox LS, Nollen NL, Ahluwalia JS, Benowitz NL, Knight J, Swardfager W, Tyndale RF. PMID: 34791718.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    44. Secondhand smoke exposure in school children in Malta assessed through urinary biomarkers. Environ Res. 2022 03; 204(Pt D):112405. Aquilina NJ, Jacob P, Benowitz NL, Fsadni P, Montefort S. PMID: 34822856; PMCID: PMC9119146.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    45. Determination of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK) arising from tobacco smoke in airborne particulate matter. Environ Int. 2022 01; 158:106992. Aquilina NJ, Havel CM, Harrison RM, Ho KF, Benowitz NL, Jacob Iii P. PMID: 34991253; PMCID: PMC9056076.
      View in: PubMed   Mentions: 1     Fields:    Translation:PHPublic Health
    46. Tobacco use disorder and cardiovascular health. Addiction. 2022 04; 117(4):1128-1138. Benowitz NL, Liakoni E. PMID: 34590373.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    47. Analyses of nicotine metabolism biomarker genetics stratified by sex in African and European Americans. Sci Rep. 2021 10 01; 11(1):19572. Chenoweth MJ, Cox LS, Nollen NL, Ahluwalia JS, Benowitz NL, Lerman C, Knight J, Tyndale RF. PMID: 34599228; PMCID: PMC8486765.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    48. Functional characterization of novel rare CYP2A6 variants and potential implications for clinical outcomes. Clin Transl Sci. 2022 01; 15(1):204-220. El-Boraie A, Tanner JA, Zhu AZX, Claw KG, Prasad B, Schuetz EG, Thummel KE, Fukunaga K, Mushiroda T, Kubo M, Benowitz NL, Lerman C, Tyndale RF. PMID: 34476898; PMCID: PMC8742641.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    49. A Multicenter, Double-Blind, Randomized, Placebo-Controlled Phase 2b Trial of Cytisinicline in Adult Smokers (The ORCA-1 Trial). Nicotine Tob Res. 2021 08 29; 23(10):1656-1663. Nides M, Rigotti NA, Benowitz N, Clarke A, Jacobs C. PMID: 33847362; PMCID: PMC8403245.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    50. Balancing Consideration of the Risks and Benefits of E-Cigarettes. Am J Public Health. 2021 09; 111(9):1661-1672. Balfour DJK, Benowitz NL, Colby SM, Hatsukami DK, Lando HA, Leischow SJ, Lerman C, Mermelstein RJ, Niaura R, Perkins KA, Pomerleau OF, Rigotti NA, Swan GE, Warner KE, West R. PMID: 34410826; PMCID: PMC8589069.
      View in: PubMed   Mentions: 72     Fields:    Translation:Humans
    51. Clinical Pharmacology of Electronic Nicotine Delivery Systems (ENDS): Implications for Benefits and Risks in the Promotion of the Combusted Tobacco Endgame. J Clin Pharmacol. 2021 08; 61 Suppl 2:S18-S36. Benowitz NL, St Helen G, Liakoni E. PMID: 34396553; PMCID: PMC9239851.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    52. Effect of race and glucuronidation rates on the relationship between nicotine metabolite ratio and nicotine clearance. Pharmacogenet Genomics. 2021 07 01; 31(5):97-107. Liakoni E, Tyndale RF, Jacob P, Dempsey DA, Addo N, Benowitz NL. PMID: 33675323; PMCID: PMC8184575.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    53. A mixed effects model for analyzing area under the curve of longitudinally measured biomarkers with missing data. Pharm Stat. 2021 11; 20(6):1249-1264. Shi L, Hatsukami DK, Koopmeiners JS, Le CT, Benowitz NL, Donny EC, Luo X. PMID: 34151513; PMCID: PMC8604790.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    54. 3-Ethenylpyridine Measured in Urine of Active and Passive Smokers: A Promising Biomarker and Toxicological Implications. Chem Res Toxicol. 2021 06 21; 34(6):1630-1639. Liu J, Benowitz NL, Hatsukami DK, Havel CM, Lazcano-Ponce E, Strasser AA, Jacob P. PMID: 33998799; PMCID: PMC8217284.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    55. Estimation of risk of neuropsychiatric adverse events from varenicline, bupropion and nicotine patch versus placebo: secondary analysis of results from the EAGLES trial using Bayes factors. Addiction. 2021 10; 116(10):2816-2824. Beard E, Jackson SE, Anthenelli RM, Benowitz NL, Aubin LS, McRae T, Lawrence D, Russ C, Krishen A, Evins AE, West R. PMID: 33885203; PMCID: PMC8612131.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    56. Nicotine metabolite ratio: Comparison of the three urinary versions to the plasma version and nicotine clearance in three clinical studies. Drug Alcohol Depend. 2021 06 01; 223:108708. Giratallah HK, Chenoweth MJ, Addo N, Ahluwalia JS, Cox LS, Lerman C, George TP, Benowitz NL, Tyndale RF. PMID: 33873029; PMCID: PMC8133391.
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    57. Thirdhand smoke associations with the gut microbiomes of infants admitted to a neonatal intensive care unit: An observational study. Environ Res. 2021 06; 197:111180. Northrup TF, Stotts AL, Suchting R, Matt GE, Quintana PJE, Khan AM, Green C, Klawans MR, Johnson M, Benowitz N, Jacob P, Hoh E, Hovell MF, Stewart CJ. PMID: 33865820; PMCID: PMC8187318.
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    58. Correlates of the nicotine metabolite ratio in Alaska Native people who smoke cigarettes. Exp Clin Psychopharmacol. 2022 Jun; 30(3):359-364. Vogel EA, Benowitz NL, Skan J, Schnellbaecher M, Prochaska JJ. PMID: 33856821; PMCID: PMC8517031.
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    59. Nicotine delivery and cigarette equivalents from vaping a JUULpod. Tob Control. 2022 08; 31(e1):e88-e93. Prochaska JJ, Vogel EA, Benowitz N. PMID: 33762429; PMCID: PMC8460696.
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    60. Ascorbic Acid Prevents Vascular Endothelial Dysfunction Induced by Electronic Hookah (Waterpipe) Vaping. J Am Heart Assoc. 2021 02; 10(5):e019271. Rezk-Hanna M, Seals DR, Rossman MJ, Gupta R, Nettle CO, Means A, Dobrin D, Cheng CW, Brecht ML, Mosenifar Z, Araujo JA, Benowitz NL. PMID: 33615833; PMCID: PMC8174254.
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    61. E-Cigarettes and Cardiopulmonary Health. Function (Oxf). 2021; 2(2):zqab004. Tarran R, Barr RG, Benowitz NL, Bhatnagar A, Chu HW, Dalton P, Doerschuk CM, Drummond MB, Gold DR, Goniewicz ML, Gross ER, Hansel NN, Hopke PK, Kloner RA, Mikheev VB, Neczypor EW, Pinkerton KE, Postow L, Rahman I, Samet JM, Salathe M, Stoney CM, Tsao PS, Widome R, Xia T, Xiao D, Wold LE. PMID: 33748758; PMCID: PMC7948134.
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    62. Ubiquitous atmospheric contamination by tobacco smoke: Nicotine and a new marker for tobacco smoke-derived particulate matter, nicotelline. Environ Int. 2021 05; 150:106417. Aquilina NJ, Havel CM, Cheung P, Harrison RM, Ho KF, Benowitz NL, Jacob Iii P. PMID: 33561671; PMCID: PMC7987222.
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    63. Assessment of Racial Differences in Pharmacotherapy Efficacy for Smoking Cessation: Secondary Analysis of the EAGLES Randomized Clinical Trial. JAMA Netw Open. 2021 01 04; 4(1):e2032053. Nollen NL, Ahluwalia JS, Sanderson Cox L, Okuyemi K, Lawrence D, Samuels L, Benowitz NL. PMID: 33464316; PMCID: PMC7816102.
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    64. Transferability of Ancestry-Specific and Cross-Ancestry CYP2A6 Activity Genetic Risk Scores in African and European Populations. Clin Pharmacol Ther. 2021 10; 110(4):975-985. El-Boraie A, Chenoweth MJ, Pouget JG, Benowitz NL, Fukunaga K, Mushiroda T, Kubo M, Nollen NL, Sanderson Cox L, Lerman C, Knight J, Tyndale RF. PMID: 33300144; PMCID: PMC8187466.
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    65. "I actually finally feel like the cigarettes aren't controlling me." - Interviews with participants smoking very low nicotine content cigarettes during a residential study. Drug Alcohol Depend. 2021 02 01; 219:108465. Denlinger-Apte RL, White CM, Donny EC, Hatsukami DK, Benowitz NL, Carpenter MJ, Smith TT. PMID: 33383351; PMCID: PMC7855643.
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    66. Recruitment best practices of a cardiovascular risk reduction randomised control trial in rural Alaska Native communities. Int J Circumpolar Health. 2020 Dec; 79(1):1806639. Knox M, Skan J, Benowitz NL, Schnellbaecher M, Prochaska JJ. PMID: 32787541; PMCID: PMC7480599.
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    67. Twenty-Four-Hour Cardiovascular Effects of Electronic Cigarettes Compared With Cigarette Smoking in Dual Users. J Am Heart Assoc. 2020 12; 9(23):e017317. Benowitz NL, St Helen G, Nardone N, Addo N, Zhang JJ, Harvanko AM, Calfee CS, Jacob P. PMID: 33208019; PMCID: PMC7763797.
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    68. Efficacy and Safety of Pharmacotherapeutic Smoking Cessation Aids in Schizophrenia Spectrum Disorders: Subgroup Analysis of EAGLES. Psychiatr Serv. 2021 01 01; 72(1):7-15. Evins AE, West R, Benowitz NL, Russ C, Lawrence D, McRae T, Maravic MC, Heffner JL, Anthenelli RM. PMID: 33138708; PMCID: PMC10228639.
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    69. Effect of Pod e-Cigarettes vs Cigarettes on Carcinogen Exposure Among African American and Latinx Smokers: A Randomized Clinical Trial. JAMA Netw Open. 2020 11 02; 3(11):e2026324. Pulvers K, Nollen NL, Rice M, Schmid CH, Qu K, Benowitz NL, Ahluwalia JS. PMID: 33206193; PMCID: PMC7675102.
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    70. Relationships Between Race, Gender, and Spot Urine Levels of Biomarkers of Tobacco Exposure Vary Based on How Creatinine Is Handled in Analyses. Nicotine Tob Res. 2020 10 29; 22(11):2109-2113. Carroll DM, Cigan S, Ikuemonisan J, Hammonds T, Stepanov I, St Helen G, Benowitz N, Hatsukami DK. PMID: 32598452; PMCID: PMC7593361.
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    71. Australian smokers' experiences and perceptions of recessed and firm filter cigarettes. Tob Control. 2021 11; 30(6):660-667. Wakefield MA, Dunstone K, Brennan E, Vittiglia A, Scollo M, Durkin SJ, Hoek J, Thrasher J, Hatsukami D, Benowitz N, Samet JM. PMID: 33115960.
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    72. Corrigendum to: Changes in Use Patterns Over 1 Year Among Smokers and Dual Users of Combustible and Electronic Cigarettes. Nicotine Tob Res. 2020 10 08; 22(10):1934. Piper ME, Baker TB, Benowitz NL, Jorenby DE. PMID: 31609417; PMCID: PMC7542636.
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    73. Exposure to a Tobacco-Specific Carcinogen Among Adolescent Smokeless Tobacco Users in Rural California, United States. Nicotine Tob Res. 2020 10 08; 22(10):1764-1771. Chaffee BW, Jacob P, Couch ET, Benowitz NL. PMID: 31504879; PMCID: PMC7542655.
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    74. Relations among cigarette dependence, e-cigarette dependence, and key dependence criteria among dual users of combustible and e-cigarettes. Psychol Addict Behav. 2022 Feb; 36(1):100-108. Piper ME, Baker TB, Mermelstein R, Benowitz N, Jorenby DE. PMID: 32955271; PMCID: PMC7981280.
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    75. Comprehensive Parent-Metabolite PBPK/PD Modeling Insights into Nicotine Replacement Therapy Strategies. Clin Pharmacokinet. 2020 09; 59(9):1119-1134. Kovar L, Selzer D, Britz H, Benowitz N, St Helen G, Kohl Y, Bals R, Lehr T. PMID: 32166575; PMCID: PMC7467963.
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    76. A Mobile Health Intervention for Adolescents Exposed to Secondhand Smoke: Pilot Feasibility and Efficacy Study. JMIR Form Res. 2020 Aug 19; 4(8):e18583. Nardone N, Giberson J, Prochaska JJ, Jain S, Benowitz NL. PMID: 32812888; PMCID: PMC7468632.
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    77. Effects of Nicotine Metabolic Rate on Cigarette Reinforcement. Nicotine Tob Res. 2020 07 16; 22(8):1419-1423. Liakoni E, Nardone N, St Helen G, Dempsey DA, Tyndale RF, Benowitz NL. PMID: 31725872; PMCID: PMC7364822.
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    78. Biomarkers of Exposure to Nicotine and Tobacco-Specific Nitrosamines in Adolescent Blunt Users. Nicotine Tob Res. 2020 07 16; 22(8):1428-1429. Nardone N, Jain S, Benowitz NL. PMID: 31433049.
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    79. Analysis of Multiple Biomarkers Using Structural Equation Modeling. Tob Regul Sci. 2020 Jul; 6(4):266-278. Cao W, Hecht SS, Murphy SE, Chu H, Benowitz NL, Donny EC, Hatsukami DK, Luo X. PMID: 35530662; PMCID: PMC9075702.
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    80. Cigarette Smoking and ARDS After Blunt Trauma: The Influence of Changing Smoking Patterns and Resuscitation Practices. Chest. 2020 10; 158(4):1490-1498. Moazed F, Hendrickson C, Conroy A, Kornblith LZ, Benowitz NL, Delucchi K, Cohen MJ, Calfee CS. PMID: 32574574; PMCID: PMC7545485.
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    81. Cultural and demographic correlates of dual tobacco use in a sample of Alaska Native adults who smoke cigarettes. Tob Induc Dis. 2020; 18:55. Epperson AE, Crouch M, Skan J, Benowitz NL, Schnellbaecher M, Prochaska JJ. PMID: 32587486; PMCID: PMC7309271.
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    82. Biomarkers of Exposure for Dual Use of Electronic Cigarettes and Combustible Cigarettes: Nicotelline, NNAL, and Total Nicotine Equivalents. Nicotine Tob Res. 2020 06 12; 22(7):1107-1113. Jacob P, St Helen G, Yu L, Nardone N, Havel C, Cheung P, Benowitz NL. PMID: 31833541; PMCID: PMC7291810.
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    83. Characterization of Nicotine Salts in 23 Electronic Cigarette Refill Liquids. Nicotine Tob Res. 2020 06 12; 22(7):1239-1243. Harvanko AM, Havel CM, Jacob P, Benowitz NL. PMID: 31821492; PMCID: PMC7291795.
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    84. Development and Piloting Testing of an Experimental Tobacco and Nicotine Product Marketplace. Nicotine Tob Res. 2020 06 12; 22(7):1230-1234. Carroll DM, Strayer L, Nardone N, Pacek LR, Kozink RV, Tessier K, McClernon J, Benowitz N, Bickel WK, Hatsukami D. PMID: 31603515; PMCID: PMC7291811.
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    85. Biochemical Verification of Tobacco Use and Abstinence: 2019 Update. Nicotine Tob Res. 2020 06 12; 22(7):1086-1097. Benowitz NL, Bernert JT, Foulds J, Hecht SS, Jacob P, Jarvis MJ, Joseph A, Oncken C, Piper ME. PMID: 31570931; PMCID: PMC7882145.
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    86. Changes in Use Patterns Over 1 Year Among Smokers and Dual Users of Combustible and Electronic Cigarettes. Nicotine Tob Res. 2020 04 21; 22(5):672-680. Piper ME, Baker TB, Benowitz NL, Jorenby DE. PMID: 31058284; PMCID: PMC7457322.
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    87. E-cigarette Dependence Measures in Dual Users: Reliability and Relations With Dependence Criteria and E-cigarette Cessation. Nicotine Tob Res. 2020 04 21; 22(5):756-763. Piper ME, Baker TB, Benowitz NL, Smith SS, Jorenby DE. PMID: 30874804; PMCID: PMC7368344.
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    88. Evaluation of nicotine patch adherence measurement using self-report and saliva cotinine among abstainers in a smoking cessation trial. Drug Alcohol Depend. 2020 05 01; 210:107967. Schnoll R, Paul Wileyto E, Gross R, Hitsman B, Hawk LW, Cinciripini P, George TP, Benowitz NL, Fen Lubitz S, Ashare R, Tyndale RF, Lerman C. PMID: 32224420; PMCID: PMC7190433.
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    89. Peripheral Blood Flow Changes to Cutaneous and Muscular Beds in Response to Acute Hookah Smoking. Am J Cardiol. 2020 06 01; 125(11):1725-1731. Rezk-Hanna M, Nelson MD, Rader F, Benowitz NL, Rosenberry R, Chang LC, Li N, Tashkin DP, Elashoff RM, Victor RG. PMID: 32278465.
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    90. Comparison of smoking cessation rates of Quitline users in Korea between smokers of ultra-low nicotine yield cigarettes and other types of cigarette: a prospective study. Addiction. 2020 09; 115(9):1745-1753. Park EY, Park E, Jeong BY, Park J, Lee DH, Benowitz NL, Lim MK. PMID: 32083364; PMCID: PMC7522678.
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    91. Mouth-Level Nicotine Intake Estimates from Discarded Filter Butts to Examine Compensatory Smoking in Low Nicotine Cigarettes. Cancer Epidemiol Biomarkers Prev. 2020 03; 29(3):643-649. Smith TT, Koopmeiners JS, Hatsukami DK, Tessier KM, Benowitz NL, Murphy SE, Strasser AA, Tidey JW, Blount BC, Valentin L, Bravo Cardenas R, Watson C, Pirkle JL, Donny EC. PMID: 32102909; PMCID: PMC7100998.
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    92. The Impact of Exclusive Use of Very Low Nicotine Cigarettes on Compensatory Smoking: An Inpatient Crossover Clinical Trial. Cancer Epidemiol Biomarkers Prev. 2020 04; 29(4):880-886. Smith TT, Koopmeiners JS, White CM, Denlinger-Apte RL, Pacek LR, De Jesús VR, Wang L, Watson C, Blount BC, Hatsukami DK, Benowitz NL, Donny EC, Carpenter MJ. PMID: 32102910; PMCID: PMC7125007.
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    93. Relationships between the Nicotine Metabolite Ratio and a Panel of Exposure and Effect Biomarkers: Findings from Two Studies of U.S. Commercial Cigarette Smokers. Cancer Epidemiol Biomarkers Prev. 2020 04; 29(4):871-879. Carroll DM, Murphy SE, Benowitz NL, Strasser AA, Kotlyar M, Hecht SS, Carmella SG, McClernon FJ, Pacek LR, Dermody SS, Vandrey RG, Donny EC, Hatsukami DK. PMID: 32051195; PMCID: PMC7437528.
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    94. Twenty-four-hour subjective and pharmacological effects of ad-libitum electronic and combustible cigarette use among dual users. Addiction. 2020 06; 115(6):1149-1159. Harvanko AM, St Helen G, Nardone N, Addo N, Benowitz NL. PMID: 31837232; PMCID: PMC7255919.
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    95. Urine Metabolites for Estimating Daily Intake of Nicotine From Cigarette Smoking. Nicotine Tob Res. 2020 02 06; 22(2):288-292. Benowitz NL, St Helen G, Nardone N, Cox LS, Jacob P. PMID: 30852610; PMCID: PMC7297087.
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    96. Differences in nicotine intake and effects from electronic and combustible cigarettes among dual users. Addiction. 2020 04; 115(4):757-767. St Helen G, Nardone N, Addo N, Dempsey D, Havel C, Jacob P, Benowitz NL. PMID: 31691397; PMCID: PMC7339816.
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    97. Seizures After Vaping Nicotine in Youth: A Canary or a Red Herring? J Adolesc Health. 2020 01; 66(1):1-2. Benowitz NL. PMID: 31866053.
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    98. Effects of Very Low Nicotine Content Cigarettes on Smoking Behavior and Biomarkers of Exposure in Menthol and Non-menthol Smokers. Nicotine Tob Res. 2019 12 23; 21(Suppl 1):S63-S72. Denlinger-Apte RL, Kotlyar M, Koopmeiners JS, Tidey JW, Luo X, Benowitz NL, Jensen JA, Ikuemonisan JO, Pacek LR, Smith TT, Vandrey R, Donny EC, Hatsukami DK. PMID: 31867637; PMCID: PMC6939781.
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    99. The Role of Compensation in Nicotine Reduction. Nicotine Tob Res. 2019 12 23; 21(Suppl 1):S16-S18. Benowitz NL, Donny EC, Edwards KC, Hatsukami D, Smith TT. PMID: 31867654; PMCID: PMC6939759.
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    100. Sources and Biomarkers of Secondhand Tobacco Smoke Exposure in Urban Adolescents. Acad Pediatr. 2020 May - Jun; 20(4):493-500. Nardone N, Jain S, Addo N, St Helen G, Jacob P, Benowitz NL. PMID: 31866460; PMCID: PMC7967984.
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    101. The influence of nicotine metabolic rate on working memory over 6 hours of abstinence from nicotine. Pharmacol Biochem Behav. 2020 01; 188:172836. Nardone N, Shahid M, Strasser AA, Dempsey DA, Benowitz NL. PMID: 31812759; PMCID: PMC7009742.
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    102. Effect of e-cigarette flavors on nicotine delivery and puffing topography: results from a randomized clinical trial of daily smokers. Psychopharmacology (Berl). 2020 Feb; 237(2):491-502. Voos N, Smith D, Kaiser L, Mahoney MC, Bradizza CM, Kozlowski LT, Benowitz NL, O'Connor RJ, Goniewicz ML. PMID: 31773209; PMCID: PMC7691130.
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    103. Impact of early nausea on varenicline adherence and smoking cessation. Addiction. 2020 01; 115(1):134-144. Peng AR, Swardfager W, Benowitz NL, Ahluwalia JS, Lerman C, Nollen NL, Tyndale RF. PMID: 31502736; PMCID: PMC6933078.
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    104. Current advances in research in treatment and recovery: Nicotine addiction. Sci Adv. 2019 10; 5(10):eaay9763. Prochaska JJ, Benowitz NL. PMID: 31663029; PMCID: PMC6795520.
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    105. Factors That Explain Differences in Abstinence Between Black and White Smokers: A Prospective Intervention Study. J Natl Cancer Inst. 2019 10 01; 111(10):1078-1087. Nollen NL, Mayo MS, Sanderson Cox L, Benowitz NL, Tyndale RF, Ellerbeck EF, Scheuermann TS, Ahluwalia JS. PMID: 30657926; PMCID: PMC6792072.
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    106. E-Hookah Versus E-Cigarettes: Findings From Wave 2 of the PATH Study (2014-2015). Am J Prev Med. 2019 11; 57(5):e163-e173. Rezk-Hanna M, Toyama J, Ikharo E, Brecht ML, Benowitz NL. PMID: 31564602.
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    107. Comparison of Systemic Exposure to Toxic and/or Carcinogenic Volatile Organic Compounds (VOC) during Vaping, Smoking, and Abstention. Cancer Prev Res (Phila). 2020 02; 13(2):153-162. St Helen G, Liakoni E, Nardone N, Addo N, Jacob P, Benowitz NL. PMID: 31554628; PMCID: PMC7007368.
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    108. Quantitative biochemical screening for marijuana use and concordance with tobacco use in urban adolescents. Drug Alcohol Depend. 2019 12 01; 205:107583. Benowitz N, Nardone N, St Helen G, Addo N, Jacob P, Liakoni E, Jain S, Hooshfar S, Lynch K. PMID: 31600618; PMCID: PMC6893148.
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    109. E-cigarettes and dual nicotine replacement therapy for smoking cessation. Lancet Respir Med. 2020 01; 8(1):7-8. Benowitz NL. PMID: 31515174.
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    110. Reductions in urinary metabolites of exposure to household air pollution in pregnant, rural Guatemalan women provided liquefied petroleum gas stoves. J Expo Sci Environ Epidemiol. 2020 03; 30(2):362-373. Weinstein JR, Diaz-Artiga A, Benowitz N, Thompson LM. PMID: 31477781; PMCID: PMC7044065.
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    111. Relationship between skin melanin index and nicotine pharmacokinetics in African American smokers. Drug Alcohol Depend. 2019 11 01; 204:107474. Liakoni E, St Helen G, Dempsey DA, Jacob P, Tyndale RF, Benowitz NL. PMID: 31521954; PMCID: PMC7272190.
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    112. Cardiovascular Effects of Hookah Smoking: Potential Implications for Cardiovascular Risk. Nicotine Tob Res. 2019 08 19; 21(9):1151-1161. Rezk-Hanna M, Benowitz NL. PMID: 29660041.
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    113. Dual Users Compared to Smokers: Demographics, Dependence, and Biomarkers. Nicotine Tob Res. 2019 08 19; 21(9):1279-1284. Piper ME, Baker TB, Benowitz NL, Kobinsky KH, Jorenby DE. PMID: 30365010; PMCID: PMC7182769.
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    114. Differences in exposure to toxic and/or carcinogenic volatile organic compounds between Black and White cigarette smokers. J Expo Sci Environ Epidemiol. 2021 03; 31(2):211-223. St Helen G, Benowitz NL, Ko J, Jacob P, Gregorich SE, Pérez-Stable EJ, Murphy SE, Hecht SS, Hatsukami DK, Donny EC. PMID: 31406274; PMCID: PMC7012700.
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    115. JUUL electronic cigarettes: Nicotine exposure and the user experience. Drug Alcohol Depend. 2019 10 01; 203:83-87. Nardone N, Helen GS, Addo N, Meighan S, Benowitz NL. PMID: 31408770; PMCID: PMC7339945.
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    116. Cytisine for nicotine addiction treatment: a review of pharmacology, therapeutics and an update of clinical trial evidence for smoking cessation. Addiction. 2019 11; 114(11):1951-1969. Tutka P, Vinnikov D, Courtney RJ, Benowitz NL. PMID: 31240783.
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    117. Effects of immediate versus gradual nicotine reduction in cigarettes on biomarkers of biological effects. Addiction. 2019 10; 114(10):1824-1833. Hatsukami DK, Luo X, Heskin AK, Tang MK, Carmella SG, Jensen J, Robinson JD, Vandrey R, Drobes DJ, Strasser AA, al'Absi M, Leischow S, Cinciripini PM, Koopmeiners J, Ikuemonisan J, Benowitz NL, Donny EC, Hecht SS. PMID: 31140663; PMCID: PMC6732016.
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    118. Black Light Smokers: How Nicotine Intake and Carcinogen Exposure Differ Across Various Biobehavioral Factors. J Natl Med Assoc. 2019 Oct; 111(5):509-520. St Helen G, Benowitz NL, Ahluwalia JS, Tyndale RF, Addo N, Gregorich SE, Pérez-Stable EJ, Cox LS. PMID: 31084916; PMCID: PMC6842416.
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    119. High Carbon Monoxide Levels from Charcoal Combustion Mask Acute Endothelial Dysfunction Induced by Hookah (Waterpipe) Smoking in Young Adults. Circulation. 2019 05 07; 139(19):2215-2224. Rezk-Hanna M, Mosenifar Z, Benowitz NL, Rader F, Rashid M, Davoren K, Moy NB, Doering L, Robbins W, Sarna L, Li N, Chang LC, Elashoff RM, Victor RG. PMID: 30764644.
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    120. Randomized within-subject trial to evaluate smokers' initial perceptions, subjective effects and nicotine delivery across six vaporized nicotine products. Addiction. 2019 07; 114(7):1236-1248. Voos N, Kaiser L, Mahoney MC, Bradizza CM, Kozlowski LT, Benowitz NL, O'Connor RJ, Goniewicz ML. PMID: 30851137; PMCID: PMC6646880.
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    121. Longitudinal stability in cigarette smokers of urinary eicosanoid biomarkers of oxidative damage and inflammation. PLoS One. 2019; 14(4):e0215853. Carmella SG, Heskin AK, Tang MK, Jensen J, Luo X, Le CT, Murphy SE, Benowitz NL, McClernon FJ, Vandrey R, Allen SS, Denlinger-Apte R, Cinciripini PM, Strasser AA, al'Absi M, Robinson JD, Donny EC, Hatsukami DK, Hecht SS. PMID: 31022220; PMCID: PMC6483352.
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    122. Predictors of Neuropsychiatric Adverse Events with Smoking Cessation Medications in the Randomized Controlled EAGLES Trial. J Gen Intern Med. 2019 06; 34(6):862-870. Anthenelli RM, Gaffney M, Benowitz NL, West R, McRae T, Russ C, Lawrence D, St Aubin L, Krishen A, Evins AE. PMID: 30847828; PMCID: PMC6544691.
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    123. Neuropsychiatric Safety and Efficacy of Varenicline, Bupropion, and Nicotine Patch in Smokers With Psychotic, Anxiety, and Mood Disorders in the EAGLES Trial. J Clin Psychopharmacol. 2019 Mar/Apr; 39(2):108-116. Evins AE, Benowitz NL, West R, Russ C, McRae T, Lawrence D, Krishen A, St Aubin L, Maravic MC, Anthenelli RM. PMID: 30811371; PMCID: PMC6488024.
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    124. Vascular Aging Is Accelerated in Flight Attendants With Occupational Secondhand Smoke Exposure. J Occup Environ Med. 2019 03; 61(3):197-202. Wei J, Shufelt C, Oestreicher Stock E, Mills C, Dhawan S, Jacob R, Torbati T, Cook-Wiens G, Benowitz N, Jacob P, Ganz P, Bairey Merz CN, Redberg R. PMID: 30475308; PMCID: PMC6698135.
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    125. Evaluation of a weighted genetic risk score for the prediction of biomarkers of CYP2A6 activity. Addict Biol. 2020 01; 25(1):e12741. El-Boraie A, Taghavi T, Chenoweth MJ, Fukunaga K, Mushiroda T, Kubo M, Lerman C, Nollen NL, Benowitz NL, Tyndale RF. PMID: 30815984; PMCID: PMC7527027.
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    126. Loperamide associated torsades de pointes, in the setting of complete heart block at marginally supratherapeutic dosing (20mg/day). Clin Toxicol (Phila). 2019 11; 57(11):1123-1124. Goodnough R, Nomura M, Badea A, Lynch KL, Benowitz NL, Tsutaoka B. PMID: 30777457.
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    127. Butanediol Conversion to Gamma-Hydroxybutyrate Markedly Reduced by the Alcohol Dehydrogenase Blocker Fomepizole. Clin Pharmacol Ther. 2019 05; 105(5):1196-1203. Liakoni E, Gugelmann H, Dempsey DA, Wiegand TJ, Havel C, Jacob P, Benowitz NL. PMID: 30450642; PMCID: PMC6465153.
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    128. Evaluating the temporal relationships between withdrawal symptoms and smoking relapse. Psychol Addict Behav. 2019 Mar; 33(2):105-116. Robinson JD, Li L, Chen M, Lerman C, Tyndale RF, Schnoll RA, Hawk LW, George TP, Benowitz NL, Cinciripini PM. PMID: 30614717; PMCID: PMC6405298.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    129. Longitudinal stability in cigarette smokers of urinary biomarkers of exposure to the toxicants acrylonitrile and acrolein. PLoS One. 2019; 14(1):e0210104. Chen M, Carmella SG, Sipe C, Jensen J, Luo X, Le CT, Murphy SE, Benowitz NL, McClernon FJ, Vandrey R, Allen SS, Denlinger-Apte R, Cinciripini PM, Strasser AA, al'Absi M, Robinson JD, Donny EC, Hatsukami D, Hecht SS. PMID: 30608961; PMCID: PMC6319718.
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    130. Managing Cannabis Use in Patients With Cardiovascular Disease. Can J Cardiol. 2019 02; 35(2):138-141. Benowitz NL. PMID: 30760417.
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    131. Identification and quantification of electronic cigarette exhaled aerosol residue chemicals in field sites. Environ Res. 2019 03; 170:351-358. Khachatoorian C, Jacob P, Sen A, Zhu Y, Benowitz NL, Talbot P. PMID: 30623881; PMCID: PMC6410739.
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    132. Reprint of: Prevention and Treatment of Tobacco Use: JACC Health Promotion Series. J Am Coll Cardiol. 2018 12 11; 72(23 Pt B):2964-2979. Kalkhoran S, Benowitz NL, Rigotti NA. PMID: 30522631.
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    133. 2018 ACC Expert Consensus Decision Pathway on Tobacco Cessation Treatment: A Report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents. J Am Coll Cardiol. 2018 12 25; 72(25):3332-3365. Barua RS, Rigotti NA, Benowitz NL, Cummings KM, Jazayeri MA, Morris PB, Ratchford EV, Sarna L, Stecker EC, Wiggins BS. PMID: 30527452.
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    134. Urine 4-(methylnitrosamino)-1-(3) pyridyl-1-butanol and cotinine in Alaska native postpartum women and neonates comparing smokers and smokeless tobacco users. Int J Circumpolar Health. 2018 Dec; 77(1):1528125. Benowitz NL, Flanagan CA, Thomas TK, Koller KR, Wolfe AW, Renner CC, Hughes C, Decker PA, Hatsukami DK, Murphy NJ, Patten C. PMID: 30325719; PMCID: PMC6197029.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    135. Effects of Nicotine Metabolic Rate on Withdrawal Symptoms and Response to Cigarette Smoking After Abstinence. Clin Pharmacol Ther. 2019 03; 105(3):641-651. Liakoni E, Edwards KC, St Helen G, Nardone N, Dempsey DA, Tyndale RF, Benowitz NL. PMID: 30242831; PMCID: PMC7967935.
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    136. Biomarker feedback intervention for smoking cessation among Alaska Native pregnant women: Randomized pilot study. Patient Educ Couns. 2019 Mar; 102(3):528-535. Patten CA, Koller KR, Flanagan CA, Hiratsuka VY, Hughes CA, Wolfe AW, Decker PA, Fruth K, Brockman TA, Korpela M, Gamez D, Bronars C, Murphy NJ, Hatsukami D, Benowitz NL, Thomas TK. PMID: 30391300; PMCID: PMC6421103.
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    137. Effect of γ-hydroxybutyrate (GHB) on driving as measured by a driving simulator. Psychopharmacology (Berl). 2018 Nov; 235(11):3223-3232. Liakoni E, Dempsey DA, Meyers M, Murphy NG, Fiorentino D, Havel C, Haller C, Benowitz NL. PMID: 30232528; PMCID: PMC6457903.
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    138. Effect of Immediate vs Gradual Reduction in Nicotine Content of Cigarettes on Biomarkers of Smoke Exposure: A Randomized Clinical Trial. JAMA. 2018 09 04; 320(9):880-891. Hatsukami DK, Luo X, Jensen JA, al'Absi M, Allen SS, Carmella SG, Chen M, Cinciripini PM, Denlinger-Apte R, Drobes DJ, Koopmeiners JS, Lane T, Le CT, Leischow S, Luo K, McClernon FJ, Murphy SE, Paiano V, Robinson JD, Severson H, Sipe C, Strasser AA, Strayer LG, Tang MK, Vandrey R, Hecht SS, Benowitz NL, Donny EC. PMID: 30193275; PMCID: PMC6372240.
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    139. IQOS: examination of Philip Morris International's claim of reduced exposure. Tob Control. 2018 11; 27(Suppl 1):s30-s36. St Helen G, Jacob Iii P, Nardone N, Benowitz NL. PMID: 30158205; PMCID: PMC6252487.
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    140. Electronic cigarette chemicals transfer from a vape shop to a nearby business in a multiple-tenant retail building. Tob Control. 2019 09; 28(5):519-525. Khachatoorian C, Jacob Iii P, Benowitz NL, Talbot P. PMID: 30158206; PMCID: PMC6458093.
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    141. Prevention and Treatment of Tobacco Use: JACC Health Promotion Series. J Am Coll Cardiol. 2018 08 28; 72(9):1030-1045. Kalkhoran S, Benowitz NL, Rigotti NA. PMID: 30139432; PMCID: PMC6261256.
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    142. Association of Reduced Nicotine Content Cigarettes With Smoking Behaviors and Biomarkers of Exposure Among Slow and Fast Nicotine Metabolizers: A Nonrandomized Clinical Trial. JAMA Netw Open. 2018 08; 1(4):e181346. Mercincavage M, Lochbuehler K, Wileyto EP, Benowitz NL, Tyndale RF, Lerman C, Strasser AA. PMID: 30627706; PMCID: PMC6322845.
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    143. Another Article About E-Cigarettes: Why Should I Care? J Am Heart Assoc. 2018 07 14; 7(14). Cummings KM, Morris PB, Benowitz NL. PMID: 30007935; PMCID: PMC6064866.
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    144. Stimulant drugs are associated with violent and penetrating trauma. Am J Emerg Med. 2019 04; 37(4):645-650. Armenian P, Effron Z, Garbi N, Dirks R, Benowitz NL, Gerona RR. PMID: 30914133.
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    145. Nicotine Reduction Strategy: State of the science and challenges to tobacco control policy and FDA tobacco product regulation. Prev Med. 2018 12; 117:5-7. Benowitz NL, Henningfield JE. PMID: 29944901.
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    146. Secondhand smoke exposure and asthma outcomes among African-American and Latino children with asthma. Thorax. 2018 11; 73(11):1041-1048. Neophytou AM, Oh SS, White MJ, Mak ACY, Hu D, Huntsman S, Eng C, Serebrisky D, Borrell LN, Farber HJ, Meade K, Davis A, Avila PC, Thyne SM, Rodríguez-Cintrón W, Rodríguez-Santana JR, Kumar R, Brigino-Buenaventura E, Sen S, Lenoir MA, Williams LK, Benowitz NL, Balmes JR, Eisen EA, Burchard EG. PMID: 29899038; PMCID: PMC6225993.
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    147. Response to "Rapid Nicotine Ratio and Successful Quitting: Acceptable Explanation" by the Authors of "Nicotine Metabolite Ratio (NMR) Prospectively Predicts Smoking Relapse: Longitudinal Findings from ITC Surveys in Five Countries". Nicotine Tob Res. 2018 06 07; 20(7):909. Fix BV, O'Connor RJ, Heckman BW, Benowitz N, Cummings MK, Fong GT, Thrasher JF. PMID: 29878262.
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    148. The Healing and Empowering Alaskan Lives Toward Healthy-Hearts (HEALTHH) Project: Study protocol for a randomized controlled trial of an intervention for tobacco use and other cardiovascular risk behaviors for Alaska Native People. Contemp Clin Trials. 2018 Aug; 71:40-46. Prochaska JJ, Epperson A, Skan J, Oppezzo M, Barnett P, Delucchi K, Schnellbaecher M, Benowitz NL. PMID: 29864548; PMCID: PMC6636857.
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    149. Impact of e-liquid flavors on e-cigarette vaping behavior. Drug Alcohol Depend. 2018 Aug 01; 189:42-48. St Helen G, Shahid M, Chu S, Benowitz NL. PMID: 29879680; PMCID: PMC6211798.
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    150. Collaborative Method Performance Study of the Measurement of Nicotine, Its Metabolites, and Total Nicotine Equivalents in Human Urine. Cancer Epidemiol Biomarkers Prev. 2018 09; 27(9):1083-1090. Wang L, Bernert JT, Benowitz NL, Feng J, Jacob P, McGahee E, Caudill SP, Scherer G, Scherer M, Pluym N, Doig MV, Newland K, Murphy SE, Caron NJ, Sander LC, Shimizu M, Yamazaki H, Kim S, Langman LJ, Pritchett JS, Sniegoski LT, Li Y, Blount BC, Pirkle JL. PMID: 29853481; PMCID: PMC6125195.
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    151. Cardiovascular Safety of Varenicline, Bupropion, and Nicotine Patch in Smokers: A Randomized Clinical Trial. JAMA Intern Med. 2018 05 01; 178(5):622-631. Benowitz NL, Pipe A, West R, Hays JT, Tonstad S, McRae T, Lawrence D, St Aubin L, Anthenelli RM. PMID: 29630702; PMCID: PMC6145797.
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    152. Factors associated with the efficacy of smoking cessation treatments and predictors of smoking abstinence in EAGLES. Addiction. 2018 08; 113(8):1507-1516. West R, Evins AE, Benowitz NL, Russ C, McRae T, Lawrence D, St Aubin L, Krishen A, Maravic MC, Anthenelli RM. PMID: 29508470; PMCID: PMC6055735.
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    153. Whether to push or pull? Nicotine reduction and non-combusted alternatives - Two strategies for reducing smoking and improving public health. Prev Med. 2018 12; 117:8-14. Smith TT, Hatsukami DK, Benowitz NL, Colby SM, McClernon FJ, Strasser AA, Tidey JW, White CM, Donny EC. PMID: 29604326; PMCID: PMC6163095.
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    154. Effects of reduced nicotine content cigarettes on individual withdrawal symptoms over time and during abstinence. Exp Clin Psychopharmacol. 2018 06; 26(3):223-232. Dermody SS, McClernon FJ, Benowitz N, Luo X, Tidey JW, Smith TT, Vandrey R, Hatsukami D, Donny EC. PMID: 29504780; PMCID: PMC5986583.
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    155. Adolescent Exposure to Toxic Volatile Organic Chemicals From E-Cigarettes. Pediatrics. 2018 04; 141(4). Rubinstein ML, Delucchi K, Benowitz NL, Ramo DE. PMID: 29507165; PMCID: PMC5869331.
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    156. Lung Microbiota Is Related to Smoking Status and to Development of Acute Respiratory Distress Syndrome in Critically Ill Trauma Patients. Am J Respir Crit Care Med. 2018 03 01; 197(5):621-631. Panzer AR, Lynch SV, Langelier C, Christie JD, McCauley K, Nelson M, Cheung CK, Benowitz NL, Cohen MJ, Calfee CS. PMID: 29035085; PMCID: PMC6005235.
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    157. Short-term early exposure to thirdhand cigarette smoke increases lung cancer incidence in mice. Clin Sci (Lond). 2018 02 28; 132(4):475-488. Hang B, Wang Y, Huang Y, Wang P, Langley SA, Bi L, Sarker AH, Schick SF, Havel C, Jacob P, Benowitz N, Destaillats H, Tang X, Xia Y, Jen KY, Gundel LA, Mao JH, Snijders AM. PMID: 29440622; PMCID: PMC6365648.
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    158. Comparison of Urine 4-(Methylnitrosamino)-1-(3)Pyridyl-1-Butanol and Cotinine for Assessment of Active and Passive Smoke Exposure in Urban Adolescents. Cancer Epidemiol Biomarkers Prev. 2018 03; 27(3):254-261. Benowitz NL, Nardone N, Jain S, Dempsey DA, Addo N, St Helen G, Jacob P. PMID: 29475963; PMCID: PMC5835192.
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    159. Tobacco Consumption and Toxicant Exposure of Cigarette Smokers Using Electronic Cigarettes. Nicotine Tob Res. 2018 01 05; 20(2):206-214. Pulvers K, Emami AS, Nollen NL, Romero DR, Strong DR, Benowitz NL, Ahluwalia JS. PMID: 28003511; PMCID: PMC6251645.
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    160. Cigarette Filter Ventilation and its Relationship to Increasing Rates of Lung Adenocarcinoma. J Natl Cancer Inst. 2017 12 01; 109(12). Song MA, Benowitz NL, Berman M, Brasky TM, Cummings KM, Hatsukami DK, Marian C, O'Connor R, Rees VW, Woroszylo C, Shields PG. PMID: 28525914; PMCID: PMC6059254.
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    161. Slower nicotine metabolism among postmenopausal Polish smokers. Pharmacol Rep. 2018 Jun; 70(3):434-438. Kosmider L, Delijewski M, Koszowski B, Sobczak A, Benowitz NL, Goniewicz ML. PMID: 29627689.
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    162. Genome-wide association study of a nicotine metabolism biomarker in African American smokers: impact of chromosome 19 genetic influences. Addiction. 2018 03; 113(3):509-523. Chenoweth MJ, Ware JJ, Zhu AZX, Cole CB, Cox LS, Nollen N, Ahluwalia JS, Benowitz NL, Schnoll RA, Hawk LW, Cinciripini PM, George TP, Lerman C, Knight J, Tyndale RF, PGRN-PNAT Research Group. PMID: 28921760; PMCID: PMC5807179.
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    163. An Electronic Cigarette Vaping Machine for the Characterization of Aerosol Delivery and Composition. Nicotine Tob Res. 2017 Oct 01; 19(10):1224-1231. Havel CM, Benowitz NL, Jacob P, St Helen G. PMID: 27281605; PMCID: PMC5896538.
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    164. Urine Cotinine Screening Detects Nearly Ubiquitous Tobacco Smoke Exposure in Urban Adolescents. Nicotine Tob Res. 2017 Sep 01; 19(9):1048-1054. Benowitz NL, Jain S, Dempsey DA, Nardone N, Helen GS, Jacob P. PMID: 28031377; PMCID: PMC5896471.
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    165. Nicotine Metabolite Ratio (NMR) Prospectively Predicts Smoking Relapse: Longitudinal Findings From ITC Surveys in Five Countries. Nicotine Tob Res. 2017 Sep 01; 19(9):1040-1047. Fix BV, O'Connor RJ, Benowitz N, Heckman BW, Cummings KM, Fong GT, Thrasher JF. PMID: 28387850; PMCID: PMC5896535.
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    166. Tobacco toxicant exposure in cigarette smokers who use or do not use other tobacco products. Drug Alcohol Depend. 2017 10 01; 179:330-336. Nollen NL, Mayo MS, Clark L, Cox LS, Khariwala SS, Pulvers K, Benowitz NL, Ahluwalia JS. PMID: 28843083; PMCID: PMC5599364.
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    167. Comprehensive Nicotine Regulation to End the Combustible Tobacco Epidemic. Ann Intern Med. 2017 Nov 21; 167(10):736-737. Benowitz NL. PMID: 28806818.
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    168. Emissions from Electronic Cigarettes: Assessing Vapers' Intake of Toxic Compounds, Secondhand Exposures, and the Associated Health Impacts. Environ Sci Technol. 2017 Aug 15; 51(16):9271-9279. Logue JM, Sleiman M, Montesinos VN, Russell ML, Litter MI, Benowitz NL, Gundel LA, Destaillats H. PMID: 28766331.
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    169. Urinary NNAL in hookah smokers and non-smokers after attending a hookah social event in a hookah lounge or a private home. Regul Toxicol Pharmacol. 2017 Oct; 89:74-82. Kassem NOF, Kassem NO, Liles S, Jackson SR, Chatfield DA, Jacob P, Benowitz NL, Hovell MF. PMID: 28716579; PMCID: PMC5582991.
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    170. Measures and predictors of varenicline adherence in the treatment of nicotine dependence. Addict Behav. 2017 12; 75:122-129. Peng AR, Morales M, Wileyto EP, Hawk LW, Cinciripini P, George TP, Benowitz NL, Nollen NL, Lerman C, Tyndale RF, Schnoll R. PMID: 28728040; PMCID: PMC5581992.
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    171. Impact of e-liquid flavors on nicotine intake and pharmacology of e-cigarettes. Drug Alcohol Depend. 2017 09 01; 178:391-398. St Helen G, Dempsey DA, Havel CM, Jacob P, Benowitz NL. PMID: 28704768; PMCID: PMC5565733.
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    172. Nicotine biomarkers and rate of nicotine metabolism among cigarette smokers taking buprenorphine for opioid dependency. Drug Alcohol Depend. 2017 09 01; 178:267-270. Gubner NR, Guydish J, Humfleet GL, Benowitz NL, Hall SM. PMID: 28683421; PMCID: PMC5553616.
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    173. Biomarkers of exposure to new and emerging tobacco delivery products. Am J Physiol Lung Cell Mol Physiol. 2017 Sep 01; 313(3):L425-L452. Schick SF, Blount BC, Jacob P, Saliba NA, Bernert JT, El Hellani A, Jatlow P, Pappas RS, Wang L, Foulds J, Ghosh A, Hecht SS, Gomez JC, Martin JR, Mesaros C, Srivastava S, St Helen G, Tarran R, Lorkiewicz PK, Blair IA, Kimmel HL, Doerschuk CM, Benowitz NL, Bhatnagar A. PMID: 28522563; PMCID: PMC5626373.
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    174. Effect of UGT2B10, UGT2B17, FMO3, and OCT2 genetic variation on nicotine and cotinine pharmacokinetics and smoking in African Americans. Pharmacogenet Genomics. 2017 04; 27(4):143-154. Taghavi T, St Helen G, Benowitz NL, Tyndale RF. PMID: 28178031; PMCID: PMC5346034.
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    175. Cardiovascular effects of electronic cigarettes. Nat Rev Cardiol. 2017 Aug; 14(8):447-456. Benowitz NL, Fraiman JB. PMID: 28332500; PMCID: PMC5519136.
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    176. Exposure to polycyclic aromatic hydrocarbons and volatile organic compounds among recently pregnant rural Guatemalan women cooking and heating with solid fuels. Int J Hyg Environ Health. 2017 06; 220(4):726-735. Weinstein JR, Asteria-Peñaloza R, Diaz-Artiga A, Davila G, Hammond SK, Ryde IT, Meyer JN, Benowitz N, Thompson LM. PMID: 28320639; PMCID: PMC5474125.
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    177. Early exposure to thirdhand cigarette smoke affects body mass and the development of immunity in mice. Sci Rep. 2017 02 03; 7:41915. Hang B, Snijders AM, Huang Y, Schick SF, Wang P, Xia Y, Havel C, Jacob P, Benowitz N, Destaillats H, Gundel LA, Mao JH. PMID: 28157226; PMCID: PMC5291208.
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    178. Thirdhand Smoke: New Evidence, Challenges, and Future Directions. Chem Res Toxicol. 2017 01 17; 30(1):270-294. Jacob P, Benowitz NL, Destaillats H, Gundel L, Hang B, Martins-Green M, Matt GE, Quintana PJ, Samet JM, Schick SF, Talbot P, Aquilina NJ, Hovell MF, Mao JH, Whitehead TP. PMID: 28001376; PMCID: PMC5501723.
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    179. Severe Carisoprodol Withdrawal After a 14-Year Addiction and Acute Overdose. J Emerg Med. 2017 May; 52(5):680-683. Vo KT, Horng H, Smollin CG, Benowitz NL. PMID: 27979642.
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    180. Reducing nicotine exposure results in weight gain in smokers randomised to very low nicotine content cigarettes. Tob Control. 2017 03; 26(e1):e43-e48. Rupprecht LE, Koopmeiners JS, Dermody SS, Oliver JA, al'Absi M, Benowitz NL, Denlinger-Apte R, Drobes DJ, Hatsukami D, McClernon FJ, Pacek LR, Smith TT, Sved AF, Tidey J, Vandrey R, Donny EC. PMID: 27856940; PMCID: PMC5428392.
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    181. Perceived risks and reasons to smoke cigarettes during pregnancy among Alaska native women. Ethn Health. 2018 Jan; 23(1):33-42. Bronars C, Patten C, Koller K, Hatsukami D, Flanagan CA, Decker PA, Hanson A, Wolfe A, Hughes C, Benowitz N, Murphy NJ, Thomas T. PMID: 27842438; PMCID: PMC5986277.
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    182. Smoking Cessation, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2016 11; 14(11):1430-1468. Shields PG, Herbst RS, Arenberg D, Benowitz NL, Bierut L, Luckart JB, Cinciripini P, Collins B, David S, Davis J, Hitsman B, Hyland A, Lang M, Leischow S, Park ER, Purcell WT, Selzle J, Silber A, Spencer S, Tanvetyanon T, Tiep B, Tindle HA, Tucker-Seeley R, Urbanic J, Hooper MW, Weksler B, Whitlock CW, Wood DE, Burns J, Scavone J. PMID: 27799513.
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    183. Nicotine Replacement, Topography, and Smoking Phenotypes of E-cigarettes. Tob Regul Sci. 2016 Oct; 2(4):352-362. Strasser AA, Souprountchouk V, Kaufmann A, Blazekovic S, Leone F, Benowitz NL, Schnoll RA. PMID: 27942543; PMCID: PMC5142626.
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    184. Nicotine Delivery and Vaping Behavior During ad Libitum E-cigarette Access. Tob Regul Sci. 2016 Oct; 2(4):363-376. St Helen G, Ross KC, Dempsey DA, Havel CM, Jacob P, Benowitz NL. PMID: 28393086; PMCID: PMC5381821.
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    185. "You have the right to protect your health": Perceptions of Secondhand Smoke and Exposure Mitigation Strategies in Low-Income Patients With Heart Disease, San Francisco, 2011-2012. Prev Chronic Dis. 2016 08 25; 13:E116. Brown-Johnson CG, Oppezzo M, Benowitz NL, Prochaska JJ. PMID: 27560724; PMCID: PMC5003531.
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    186. Reduced nicotine content cigarettes, e-cigarettes and the cigarette end game. Addiction. 2017 01; 112(1):6-7. Benowitz NL, Donny EC, Hatsukami DK. PMID: 27555354; PMCID: PMC5518737.
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    187. Exposure to Nicotine and Selected Toxicants in Cigarette Smokers Who Switched to Electronic Cigarettes: A Longitudinal Within-Subjects Observational Study. Nicotine Tob Res. 2017 Feb; 19(2):160-167. Goniewicz ML, Gawron M, Smith DM, Peng M, Jacob P, Benowitz NL. PMID: 27613896; PMCID: PMC5234360.
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    188. Effects of 6-Week Use of Reduced-Nicotine Content Cigarettes in Smokers With and Without Elevated Depressive Symptoms. Nicotine Tob Res. 2017 01; 19(1):59-67. Tidey JW, Pacek LR, Koopmeiners JS, Vandrey R, Nardone N, Drobes DJ, Benowitz NL, Dermody SS, Lemieux A, Denlinger RL, Cassidy R, al'Absi M, Hatsukami DK, Donny EC. PMID: 27613885; PMCID: PMC5157715.
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    189. Estimations and predictors of non-compliance in switchers to reduced nicotine content cigarettes. Addiction. 2016 12; 111(12):2208-2216. Nardone N, Donny EC, Hatsukami DK, Koopmeiners JS, Murphy SE, Strasser AA, Tidey JW, Vandrey R, Benowitz NL. PMID: 27367436; PMCID: PMC5203964.
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    190. Disposition kinetics and metabolism of nicotine and cotinine in African American smokers: impact of CYP2A6 genetic variation and enzymatic activity. Pharmacogenet Genomics. 2016 07; 26(7):340-50. Benowitz NL, St Helen G, Dempsey DA, Jacob P, Tyndale RF. PMID: 27035242; PMCID: PMC4892970.
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    191. E-cigarette use results in suppression of immune and inflammatory-response genes in nasal epithelial cells similar to cigarette smoke. Am J Physiol Lung Cell Mol Physiol. 2016 07 01; 311(1):L135-44. Martin EM, Clapp PW, Rebuli ME, Pawlak EA, Glista-Baker E, Benowitz NL, Fry RC, Jaspers I. PMID: 27288488; PMCID: PMC4967187.
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    192. Fetal Exposure to Carcinogens With Tobacco Use in Pregnancy: Phase 1 MAW Study Findings. Nicotine Tob Res. 2016 11; 18(11):2162-2168. Flanagan CA, Koller KR, Wolfe AW, Thomas TK, Benowitz NL, Renner CC, Hughes C, Hatsukami DK, Bronars C, Murphy NJ, Day G, Decker PA, Patten CA. PMID: 27190400; PMCID: PMC5055741.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    193. Racial differences in the relationship between rate of nicotine metabolism and nicotine intake from cigarette smoking. Pharmacol Biochem Behav. 2016 09; 148:1-7. Ross KC, Gubner NR, Tyndale RF, Hawk LW, Lerman C, George TP, Cinciripini P, Schnoll RA, Benowitz NL. PMID: 27180107; PMCID: PMC4972680.
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    194. Genome-Wide Association of the Laboratory-Based Nicotine Metabolite Ratio in Three Ancestries. Nicotine Tob Res. 2016 09; 18(9):1837-1844. Baurley JW, Edlund CK, Pardamean CI, Conti DV, Krasnow R, Javitz HS, Hops H, Swan GE, Benowitz NL, Bergen AW. PMID: 27113016; PMCID: PMC4978985.
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    195. Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial. Lancet. 2016 Jun 18; 387(10037):2507-20. Anthenelli RM, Benowitz NL, West R, St Aubin L, McRae T, Lawrence D, Ascher J, Russ C, Krishen A, Evins AE. PMID: 27116918.
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    196. Cessation of alcohol consumption decreases rate of nicotine metabolism in male alcohol-dependent smokers. Drug Alcohol Depend. 2016 Jun 01; 163:157-64. Gubner NR, Kozar-Konieczna A, Szoltysek-Boldys I, Slodczyk-Mankowska E, Goniewicz J, Sobczak A, Jacob P, Benowitz NL, Goniewicz ML. PMID: 27107849; PMCID: PMC4880506.
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    197. Nicotine and Anatabine Exposure from Very Low Nicotine Content Cigarettes. Tob Regul Sci. 2016 Apr; 2(2):186-203. Denlinger RL, Smith TT, Murphy SE, Koopmeiners JS, Benowitz NL, Hatsukami DK, Pacek LR, Colino C, Cwalina SN, Donny EC. PMID: 29600258; PMCID: PMC5870904.
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    198. The Influence of Puff Characteristics, Nicotine Dependence, and Rate of Nicotine Metabolism on Daily Nicotine Exposure in African American Smokers. Cancer Epidemiol Biomarkers Prev. 2016 06; 25(6):936-43. Ross KC, Dempsey DA, St Helen G, Delucchi K, Benowitz NL. PMID: 27030603; PMCID: PMC4891233.
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    199. Acute Effect of Hookah Smoking on the Human Coronary Microcirculation. Am J Cardiol. 2016 06 01; 117(11):1747-54. Nelson MD, Rezk-Hanna M, Rader F, Mason OR, Tang X, Shidban S, Rosenberry R, Benowitz NL, Tashkin DP, Elashoff RM, Lindner JR, Victor RG. PMID: 27067622; PMCID: PMC5689082.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    200. Cardiovascular toxicity of nicotine: Implications for electronic cigarette use. Trends Cardiovasc Med. 2016 08; 26(6):515-23. Benowitz NL, Burbank AD. PMID: 27079891; PMCID: PMC4958544.
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    201. Minoxidil-Associated Pleuropericardial Effusion. J Gen Intern Med. 2016 09; 31(9):1105. Brondfield M, Wu L, Benowitz N. PMID: 26951281; PMCID: PMC4978667.
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    202. Thirdhand Smoke: State of the Science and a Call for Policy Expansion. Public Health Rep. 2016 Mar-Apr; 131(2):233-8. Northrup TF, Jacob P, Benowitz NL, Hoh E, Quintana PJ, Hovell MF, Matt GE, Stotts AL. PMID: 26957657; PMCID: PMC4765971.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansPHPublic Health
    203. A clinical trial to examine disparities in quitting between African-American and White adult smokers: Design, accrual, and baseline characteristics. Contemp Clin Trials. 2016 Mar; 47:12-21. Nollen NL, Cox LS, Yu Q, Ellerbeck EF, Scheuermann TS, Benowitz NL, Tyndale RF, Mayo MS, Ahluwalia JS. PMID: 26667382; PMCID: PMC4818177.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCTClinical Trials
    204. Thirdhand smoke contamination in hospital settings: assessing exposure risk for vulnerable paediatric patients. Tob Control. 2016 11; 25(6):619-623. Northrup TF, Khan AM, Jacob P, Benowitz NL, Hoh E, Hovell MF, Matt GE, Stotts AL. PMID: 26635031; PMCID: PMC4893002.
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    205. Nicotine delivery, retention and pharmacokinetics from various electronic cigarettes. Addiction. 2016 Mar; 111(3):535-44. St Helen G, Havel C, Dempsey DA, Jacob P, Benowitz NL. PMID: 26430813; PMCID: PMC4749433.
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    206. Randomized Trial of Reduced-Nicotine Standards for Cigarettes. N Engl J Med. 2015 Oct; 373(14):1340-9. Donny EC, Denlinger RL, Tidey JW, Koopmeiners JS, Benowitz NL, Vandrey RG, al'Absi M, Carmella SG, Cinciripini PM, Dermody SS, Drobes DJ, Hecht SS, Jensen J, Lane T, Le CT, McClernon FJ, Montoya ID, Murphy SE, Robinson JD, Stitzer ML, Strasser AA, Tindle H, Hatsukami DK. PMID: 26422724; PMCID: PMC4642683.
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    207. Cardiovascular Effects of Exposure to Cigarette Smoke and Electronic Cigarettes: Clinical Perspectives From the Prevention of Cardiovascular Disease Section Leadership Council and Early Career Councils of the American College of Cardiology. J Am Coll Cardiol. 2015 Sep 22; 66(12):1378-91. Morris PB, Ference BA, Jahangir E, Feldman DN, Ryan JJ, Bahrami H, El-Chami MF, Bhakta S, Winchester DE, Al-Mallah MH, Sanchez Shields M, Deedwania P, Mehta LS, Phan BA, Benowitz NL. PMID: 26383726.
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    208. Smoking cessation and the cardiovascular patient. Curr Opin Cardiol. 2015 Sep; 30(5):506-11. Prochaska JJ, Benowitz NL. PMID: 26196657; PMCID: PMC4624444.
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    209. Cigarette Smoke Exposure and the Acute Respiratory Distress Syndrome. Crit Care Med. 2015 Sep; 43(9):1790-7. Calfee CS, Matthay MA, Kangelaris KN, Siew ED, Janz DR, Bernard GR, May AK, Jacob P, Havel C, Benowitz NL, Ware LB. PMID: 26010690; PMCID: PMC4737582.
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    210. The Past, Present, and Future of Nicotine Addiction Therapy. Annu Rev Med. 2016; 67:467-86. Prochaska JJ, Benowitz NL. PMID: 26332005; PMCID: PMC5117107.
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    211. Effect of reducing the nicotine content of cigarettes on cigarette smoking behavior and tobacco smoke toxicant exposure: 2-year follow up. Addiction. 2015 Oct; 110(10):1667-75. Benowitz NL, Nardone N, Dains KM, Hall SM, Stewart S, Dempsey D, Jacob P. PMID: 26198394; PMCID: PMC4565734.
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    212. Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption. PLoS One. 2015; 10(7):e0126113. Bergen AW, Michel M, Nishita D, Krasnow R, Javitz HS, Conneely KN, Lessov-Schlaggar CN, Hops H, Zhu AZ, Baurley JW, McClure JB, Hall SM, Baker TB, Conti DV, Benowitz NL, Lerman C, Tyndale RF, Swan GE, Transdisciplinary Research in Cancer of the Lung Research Team. PMID: 26132489; PMCID: PMC4488893.
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    213. Lack of Associations of CHRNA5-A3-B4 Genetic Variants with Smoking Cessation Treatment Outcomes in Caucasian Smokers despite Associations with Baseline Smoking. PLoS One. 2015; 10(5):e0128109. Tyndale RF, Zhu AZ, George TP, Cinciripini P, Hawk LW, Schnoll RA, Swan GE, Benowitz NL, Heitjan DF, Lerman C, PGRN-PNAT Research Group. PMID: 26010901; PMCID: PMC4444267.
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    214. Nicotine metabolite ratio (3-hydroxycotinine/cotinine) in plasma and urine by different analytical methods and laboratories: implications for clinical implementation. Cancer Epidemiol Biomarkers Prev. 2015 Aug; 24(8):1239-46. Tanner JA, Novalen M, Jatlow P, Huestis MA, Murphy SE, Kaprio J, Kankaanpää A, Galanti L, Stefan C, George TP, Benowitz NL, Lerman C, Tyndale RF. PMID: 26014804; PMCID: PMC4526326.
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    215. Nicotine Metabolite Ratio Is Associated With Lozenge Use But Not Quitting in Smokeless Tobacco Users. Nicotine Tob Res. 2016 Mar; 18(3):366-70. Ebbert JO, Severson HH, Danaher BG, Benowitz NL, Schroeder DR. PMID: 25977408; PMCID: PMC6095223.
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    216. Genetic and phenotypic variation in UGT2B17, a testosterone-metabolizing enzyme, is associated with BMI in males. Pharmacogenet Genomics. 2015 May; 25(5):263-9. Zhu AZ, Cox LS, Ahluwalia JS, Renner CC, Hatsukami DK, Benowitz NL, Tyndale RF. PMID: 25794161; PMCID: PMC4382380.
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    217. Tobacco alkaloids and tobacco-specific nitrosamines in dust from homes of smokeless tobacco users, active smokers, and nontobacco users. Chem Res Toxicol. 2015 May 18; 28(5):1007-14. Whitehead TP, Havel C, Metayer C, Benowitz NL, Jacob P. PMID: 25794360; PMCID: PMC4827423.
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    218. Guidance to employers on integrating e-cigarettes/electronic nicotine delivery systems into tobacco worksite policy. J Occup Environ Med. 2015 Mar; 57(3):334-43. Whitsel LP, Benowitz N, Bhatnagar A, Bullen C, Goldstein F, Matthias-Gray L, Grossmeier J, Harris J, Isaac F, Loeppke R, Manley M, Moseley K, Niemiec T, O'Brien V, Palma-Davis L, Pronk N, Pshock J, Stave GM, Terry P. PMID: 25742539.
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    219. Response to letter regarding article, "Electronic cigarettes: a scientific review". Circulation. 2015 Feb 10; 131(6):e342. Grana R, Benowitz N, Glantz S. PMID: 25815391.
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    220. Use of the nicotine metabolite ratio as a genetically informed biomarker of response to nicotine patch or varenicline for smoking cessation: a randomised, double-blind placebo-controlled trial. Lancet Respir Med. 2015 Feb; 3(2):131-138. Lerman C, Schnoll RA, Hawk LW, Cinciripini P, George TP, Wileyto EP, Swan GE, Benowitz NL, Heitjan DF, Tyndale RF, PGRN-PNAT Research Group. PMID: 25588294; PMCID: PMC4480925.
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    221. Nicotine Dependence, Nicotine Metabolism, and the Extent of Compensation in Response to Reduced Nicotine Content Cigarettes. Nicotine Tob Res. 2015 Sep; 17(9):1167-72. Bandiera FC, Ross KC, Taghavi S, Delucchi K, Tyndale RF, Benowitz NL. PMID: 25555385; PMCID: PMC4542742.
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    222. Secondhand tobacco smoke exposure among hospitalized nonsmokers with coronary heart disease. JAMA Intern Med. 2015 Jan; 175(1):133-6. Japuntich SJ, Eilers MA, Shenhav S, Park ER, Winickoff JP, Benowitz NL, Rigotti NA. PMID: 25383761.
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    223. Different profiles of carcinogen exposure in Chinese compared with US cigarette smokers. Tob Control. 2015 Dec; 24(e4):e258-63. Benowitz NL, Gan Q, Goniewicz ML, Lu W, Xu J, Li X, Jacob P, Glantz S. PMID: 25535294; PMCID: PMC4476967.
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    224. Compensatory smoking from gradual and immediate reduction in cigarette nicotine content. Cancer Epidemiol Biomarkers Prev. 2015 Feb; 24(2):472-6. Hatsukami DK, Donny EC, Koopmeiners JS, Benowitz NL. PMID: 25515551; PMCID: PMC4324025.
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    225. Biochemical estimation of noncompliance with smoking of very low nicotine content cigarettes. Cancer Epidemiol Biomarkers Prev. 2015 Feb; 24(2):331-5. Benowitz NL, Nardone N, Hatsukami DK, Donny EC. PMID: 25416718; PMCID: PMC4323626.
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    226. Intake of toxic and carcinogenic volatile organic compounds from secondhand smoke in motor vehicles. Cancer Epidemiol Biomarkers Prev. 2014 Dec; 23(12):2774-82. St Helen G, Jacob P, Peng M, Dempsey DA, Hammond SK, Benowitz NL. PMID: 25398951; PMCID: PMC4257856.
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    227. Cardiogenic shock after use of fluoroamphetamine confirmed with serum and urine levels. Clin Toxicol (Phila). 2014 Dec; 52(10):1292-5. Al-Abri S, Meier KH, Colby JM, Smollin CG, Benowitz NL. PMID: 25350468.
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    228. UGT1A and UGT2B genetic variation alters nicotine and nitrosamine glucuronidation in european and african american smokers. Cancer Epidemiol Biomarkers Prev. 2015 Jan; 24(1):94-104. Wassenaar CA, Conti DV, Das S, Chen P, Cook EH, Ratain MJ, Benowitz NL, Tyndale RF. PMID: 25277794; PMCID: PMC4294984.
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    229. Gene variants in CYP2C19 are associated with altered in vivo bupropion pharmacokinetics but not bupropion-assisted smoking cessation outcomes. Drug Metab Dispos. 2014 Nov; 42(11):1971-7. Zhu AZ, Zhou Q, Cox LS, Ahluwalia JS, Benowitz NL, Tyndale RF. PMID: 25187485; PMCID: PMC4201132.
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    230. Prevalence and impact of active and passive cigarette smoking in acute respiratory distress syndrome. Crit Care Med. 2014 Sep; 42(9):2058-68. Hsieh SJ, Zhuo H, Benowitz NL, Thompson BT, Liu KD, Matthay MA, Calfee CS, National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Network, National Heart Lung and Blood Institute Acute Respiratory Distress Syndrome Network. PMID: 24942512; PMCID: PMC4134734.
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    231. Electronic cigarettes: a policy statement from the American Heart Association. Circulation. 2014 Oct 14; 130(16):1418-36. Bhatnagar A, Whitsel LP, Ribisl KM, Bullen C, Chaloupka F, Piano MR, Robertson RM, McAuley T, Goff D, Benowitz N, American Heart Association Advocacy Coordinating Committee, Council on Cardiovascular and Stroke Nur. PMID: 25156991; PMCID: PMC7643636.
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    232. Organic cation transporter variation and response to smoking cessation therapies. Nicotine Tob Res. 2014 Dec; 16(12):1638-46. Bergen AW, Javitz HS, Krasnow R, Michel M, Nishita D, Conti DV, Edlund CK, Kwok PY, McClure JB, Kim RB, Hall SM, Tyndale RF, Baker TB, Benowitz NL, Swan GE. PMID: 25143296; PMCID: PMC4296186.
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    233. Electronic cigarettes: review of use, content, safety, effects on smokers and potential for harm and benefit. Addiction. 2014 Nov; 109(11):1801-10. Hajek P, Etter JF, Benowitz N, Eissenberg T, McRobbie H. PMID: 25078252; PMCID: PMC4487785.
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    234. Reduced nicotine product standards for combustible tobacco: building an empirical basis for effective regulation. Prev Med. 2014 Nov; 68:17-22. Donny EC, Hatsukami DK, Benowitz NL, Sved AF, Tidey JW, Cassidy RN. PMID: 24967958; PMCID: PMC4253911.
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    235. Nicotine and carcinogen exposure after water pipe smoking in hookah bars. Cancer Epidemiol Biomarkers Prev. 2014 Jun; 23(6):1055-66. St Helen G, Benowitz NL, Dains KM, Havel C, Peng M, Jacob P. PMID: 24836469; PMCID: PMC4047652.
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    236. E-cigarettes: a scientific review. Circulation. 2014 May 13; 129(19):1972-86. Grana R, Benowitz N, Glantz SA. PMID: 24821826; PMCID: PMC4018182.
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    237. Electronic cigarettes. Cardiology patient page. Circulation. 2014 May 13; 129(19):e490-2. Grana RA, Ling PM, Benowitz N, Glantz S. PMID: 24821830; PMCID: PMC4074376.
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    238. A comparison of nicotine biomarkers and smoking patterns in daily and nondaily smokers. Cancer Epidemiol Biomarkers Prev. 2014 Jul; 23(7):1264-72. Shiffman S, Dunbar MS, Benowitz NL. PMID: 24740202; PMCID: PMC4621008.
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    239. Association of CHRNA5-A3-B4 SNP rs2036527 with smoking cessation therapy response in African-American smokers. Clin Pharmacol Ther. 2014 Aug; 96(2):256-65. Zhu AZ, Zhou Q, Cox LS, David SP, Ahluwalia JS, Benowitz NL, Tyndale RF. PMID: 24733007; PMCID: PMC4111775.
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    240. Children's exposure to secondhand and thirdhand smoke carcinogens and toxicants in homes of hookah smokers. Nicotine Tob Res. 2014 Jul; 16(7):961-75. Kassem NO, Daffa RM, Liles S, Jackson SR, Kassem NO, Younis MA, Mehta S, Chen M, Jacob P, Carmella SG, Chatfield DA, Benowitz NL, Matt GE, Hecht SS, Hovell MF. PMID: 24590387; PMCID: PMC4072898.
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    241. Variation in P450 oxidoreductase (POR) A503V and flavin-containing monooxygenase (FMO)-3 E158K is associated with minor alterations in nicotine metabolism, but does not alter cigarette consumption. Pharmacogenet Genomics. 2014 Mar; 24(3):172-6. Chenoweth MJ, Zhu AZ, Sanderson Cox L, Ahluwalia JS, Benowitz NL, Tyndale RF. PMID: 24448396; PMCID: PMC3985268.
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    242. Emerging nicotine delivery products. Implications for public health. Ann Am Thorac Soc. 2014 Feb; 11(2):231-5. Benowitz NL. PMID: 24575992.
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    243. Novel CYP2A6 variants identified in African Americans are associated with slow nicotine metabolism in vitro and in vivo. Pharmacogenet Genomics. 2014 Feb; 24(2):118-28. Piliguian M, Zhu AZ, Zhou Q, Benowitz NL, Ahluwalia JS, Sanderson Cox L, Tyndale RF. PMID: 24305170; PMCID: PMC3931261.
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    244. Cigarette smoke toxins deposited on surfaces: implications for human health. PLoS One. 2014; 9(1):e86391. Martins-Green M, Adhami N, Frankos M, Valdez M, Goodwin B, Lyubovitsky J, Dhall S, Garcia M, Egiebor I, Martinez B, Green HW, Havel C, Yu L, Liles S, Matt G, Destaillats H, Sleiman M, Gundel LA, Benowitz N, Jacob P, Hovell M, Winickoff JP, Curras-Collazo M. PMID: 24489722; PMCID: PMC3906039.
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    245. Multiple risk-behavior profiles of smokers with serious mental illness and motivation for change. Health Psychol. 2014 Dec; 33(12):1518-29. Prochaska JJ, Fromont SC, Delucchi K, Young-Wolff KC, Benowitz NL, Hall S, Bonas T, Hall SM. PMID: 24467257; PMCID: PMC4425305.
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    246. Clinical significance of early smoking withdrawal effects and their relationships with nicotine metabolism: preliminary results from a pilot study. Nicotine Tob Res. 2014 May; 16(5):615-20. Hendricks PS, Delucchi KL, Benowitz NL, Hall SM. PMID: 24353342; PMCID: PMC3977489.
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    247. Cotinine and tobacco-specific carcinogen exposure among nondaily smokers in a multiethnic sample. Nicotine Tob Res. 2014 May; 16(5):600-5. Khariwala SS, Scheuermann TS, Berg CJ, Hayes RB, Nollen NL, Thomas JL, Guo H, Ahluwalia JS, Benowitz NL. PMID: 24297808; PMCID: PMC3988430.
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    248. Factors associated with discontinuation of bupropion and counseling among African American light smokers in a randomized clinical trial. Ann Behav Med. 2013 Dec; 46(3):336-48. Nollen NL, Mayo MS, Ahluwalia JS, Tyndale RF, Benowitz NL, Faseru B, Buchanan TS, Cox LS. PMID: 23733379; PMCID: PMC3815499.
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    249. Delayed bupropion cardiotoxicity associated with elevated serum concentrations of bupropion but not hydroxybupropion. Clin Toxicol (Phila). 2013 Dec; 51(10):1230-4. Al-Abri SA, Orengo JP, Hayashi S, Thoren KL, Benowitz NL, Olson KR. PMID: 24131328.
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    250. Nicotelline: a proposed biomarker and environmental tracer for particulate matter derived from tobacco smoke. Chem Res Toxicol. 2013 Nov 18; 26(11):1615-31. Jacob P, Goniewicz ML, Havel CM, Schick SF, Benowitz NL. PMID: 24125094; PMCID: PMC3929594.
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    251. Levels of cotinine in dried blood specimens from newborns as a biomarker of maternal smoking close to the time of delivery. Am J Epidemiol. 2013 Dec 01; 178(11):1648-54. Yang J, Pearl M, Jacob P, DeLorenze GN, Benowitz NL, Yu L, Havel C, Kharrazi M. PMID: 24068198; PMCID: PMC3842901.
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    252. Influence of a dopamine pathway additive genetic efficacy score on smoking cessation: results from two randomized clinical trials of bupropion. Addiction. 2013 Dec; 108(12):2202-11. David SP, Strong DR, Leventhal AM, Lancaster MA, McGeary JE, Munafò MR, Bergen AW, Swan GE, Benowitz NL, Tyndale RF, Conti DV, Brown RA, Lerman C, Niaura R. PMID: 23941313; PMCID: PMC3834197.
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    253. Validity of self-reported adult secondhand smoke exposure. Tob Control. 2015 Jan; 24(1):48-53. Prochaska JJ, Grossman W, Young-Wolff KC, Benowitz NL. PMID: 23997071; PMCID: PMC4458852.
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    254. Cytisine, the world's oldest smoking cessation aid. BMJ. 2013 Aug 23; 347:f5198. Prochaska JJ, Das S, Benowitz NL. PMID: 23974638.
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    255. The regulatory challenge of electronic cigarettes. JAMA. 2013 Aug 21; 310(7):685-6. Benowitz NL, Goniewicz ML. PMID: 23856948.
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    256. Genetic and pharmacokinetic determinants of response to transdermal nicotine in white, black, and Asian nonsmokers. Clin Pharmacol Ther. 2013 Dec; 94(6):687-94. Dempsey DA, St Helen G, Jacob P, Tyndale RF, Benowitz NL. PMID: 23933970; PMCID: PMC3834081.
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    257. Variation in trans-3'-hydroxycotinine glucuronidation does not alter the nicotine metabolite ratio or nicotine intake. PLoS One. 2013; 8(8):e70938. Zhu AZ, Zhou Q, Cox LS, Ahluwalia JS, Benowitz NL, Tyndale RF. PMID: 23936477; PMCID: PMC3732272.
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    258. CHRNA5-A3-B4 genetic variants alter nicotine intake and interact with tobacco use to influence body weight in Alaska Native tobacco users. Addiction. 2013 Oct; 108(10):1818-28. Zhu AZ, Renner CC, Hatsukami DK, Benowitz NL, Tyndale RF. PMID: 23692359; PMCID: PMC3775934.
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    259. CYP2A6 genotype but not age determines cotinine half-life in infants and children. Clin Pharmacol Ther. 2013 Sep; 94(3):400-6. Dempsey DA, Sambol NC, Jacob P, Hoffmann E, Tyndale RF, Fuentes-Afflick E, Benowitz NL. PMID: 23714690; PMCID: PMC3820275.
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    260. Stability of the nicotine metabolite ratio in smokers of progressively reduced nicotine content cigarettes. Nicotine Tob Res. 2013 Nov; 15(11):1939-42. St Helen G, Jacob P, Benowitz NL. PMID: 23674838; PMCID: PMC3790625.
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    261. Reducing the nicotine content to make cigarettes less addictive. Tob Control. 2013 May; 22 Suppl 1:i14-7. Benowitz NL, Henningfield JE. PMID: 23591498; PMCID: PMC3632983.
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    262. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tob Control. 2014 Mar; 23(2):133-9. Goniewicz ML, Knysak J, Gawron M, Kosmider L, Sobczak A, Kurek J, Prokopowicz A, Jablonska-Czapla M, Rosik-Dulewska C, Havel C, Jacob P, Benowitz N. PMID: 23467656; PMCID: PMC4154473.
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    263. Comparison of nicotine and carcinogen exposure with water pipe and cigarette smoking. Cancer Epidemiol Biomarkers Prev. 2013 May; 22(5):765-72. Jacob P, Abu Raddaha AH, Dempsey D, Havel C, Peng M, Yu L, Benowitz NL. PMID: 23462922; PMCID: PMC3650103.
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    264. Influence of CYP2B6 genetic variants on plasma and urine concentrations of bupropion and metabolites at steady state. Pharmacogenet Genomics. 2013 Mar; 23(3):135-41. Benowitz NL, Zhu AZ, Tyndale RF, Dempsey D, Jacob P. PMID: 23344581; PMCID: PMC3763712.
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    265. Smoking cessation after acute myocardial infarction. J Am Coll Cardiol. 2013 Feb 05; 61(5):533-5. Benowitz NL, Prochaska JJ. PMID: 23369418.
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    266. Nicotinic acetylcholine receptor variation and response to smoking cessation therapies. Pharmacogenet Genomics. 2013 Feb; 23(2):94-103. Bergen AW, Javitz HS, Krasnow R, Nishita D, Michel M, Conti DV, Liu J, Lee W, Edlund CK, Hall S, Kwok PY, Benowitz NL, Baker TB, Tyndale RF, Lerman C, Swan GE. PMID: 23249876; PMCID: PMC3563676.
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    267. The ability of plasma cotinine to predict nicotine and carcinogen exposure is altered by differences in CYP2A6: the influence of genetics, race, and sex. Cancer Epidemiol Biomarkers Prev. 2013 Apr; 22(4):708-18. Zhu AZ, Renner CC, Hatsukami DK, Swan GE, Lerman C, Benowitz NL, Tyndale RF. PMID: 23371292; PMCID: PMC3617060.
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    268. Biomarkers of secondhand smoke exposure in automobiles. Tob Control. 2014 Jan; 23(1):51-7. Jones IA, St Helen G, Meyers MJ, Dempsey DA, Havel C, Jacob P, Northcross A, Hammond SK, Benowitz NL. PMID: 23349229; PMCID: PMC3670969.
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    269. Dose-independent kinetics with low level exposure to nicotine and cotinine. Br J Clin Pharmacol. 2013 Jan; 75(1):277-9. Benowitz NL, Dempsey D, Tyndale RF, St Helen G, Jacob P. PMID: 22574797; PMCID: PMC3555070.
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    270. Race, gender, and nicotine metabolism in adolescent smokers. Nicotine Tob Res. 2013 Jul; 15(7):1311-5. Rubinstein ML, Shiffman S, Rait MA, Benowitz NL. PMID: 23239845; PMCID: PMC3682846.
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    271. The DRD4 exon III VNTR, bupropion, and associations with prospective abstinence. Nicotine Tob Res. 2013 Jul; 15(7):1190-200. Bergen AW, Javitz HS, Su L, He Y, Conti DV, Benowitz NL, Tyndale RF, Lerman C, Swan GE. PMID: 23212438; PMCID: PMC3682839.
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    272. Predictors of cessation in African American light smokers enrolled in a bupropion clinical trial. Addict Behav. 2013 Mar; 38(3):1796-803. Faseru B, Nollen NL, Mayo MS, Krebill R, Choi WS, Benowitz NL, Tyndale RF, Okuyemi KS, Ahluwalia JS, Sanderson Cox L. PMID: 23254230; PMCID: PMC3558614.
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    273. Particulate mass and polycyclic aromatic hydrocarbons exposure from secondhand smoke in the back seat of a vehicle. Tob Control. 2014 Jan; 23(1):14-20. Northcross AL, Trinh M, Kim J, Jones IA, Meyers MJ, Dempsey DD, Benowitz NL, Hammond SK. PMID: 23172398.
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    274. CYP2B6 and bupropion's smoking-cessation pharmacology: the role of hydroxybupropion. Clin Pharmacol Ther. 2012 Dec; 92(6):771-7. Zhu AZ, Cox LS, Nollen N, Faseru B, Okuyemi KS, Ahluwalia JS, Benowitz NL, Tyndale RF. PMID: 23149928; PMCID: PMC3729209.
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    275. Air quality, mortality, and economic benefits of a smoke - free workplace law for non-smoking Ontario bar workers. Indoor Air. 2013 Apr; 23(2):93-104. Repace J, Zhang B, Bondy SJ, Benowitz N, Ferrence R. PMID: 23006034.
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    276. Racial differences in the relationship between tobacco dependence and nicotine and carcinogen exposure. Addiction. 2013 Mar; 108(3):607-17. St Helen G, Dempsey D, Wilson M, Jacob P, Benowitz NL. PMID: 22971134; PMCID: PMC3553231.
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    277. Nicotine reduction: strategic research plan. Nicotine Tob Res. 2013 Jun; 15(6):1003-13. Hatsukami DK, Benowitz NL, Donny E, Henningfield J, Zeller M. PMID: 23100460; PMCID: PMC3646645.
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    278. Correlates of NNAL levels among nondaily and daily smokers in the college student population. Curr Biomark Find. 2012 Oct 15; 2012(2). Berg CJ, Schauer GL, Ahluwalia JS, Benowitz NL. PMID: 24298447; PMCID: PMC3843970.
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    279. Nicotine metabolism and addiction among adolescent smokers. Addiction. 2013 Feb; 108(2):406-12. Rubinstein ML, Shiffman S, Moscicki AB, Rait MA, Sen S, Benowitz NL. PMID: 22823143; PMCID: PMC3504133.
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    280. Alaska Native smokers and smokeless tobacco users with slower CYP2A6 activity have lower tobacco consumption, lower tobacco-specific nitrosamine exposure and lower tobacco-specific nitrosamine bioactivation. Carcinogenesis. 2013 Jan; 34(1):93-101. Zhu AZ, Binnington MJ, Renner CC, Lanier AP, Hatsukami DK, Stepanov I, Watson CH, Sosnoff CS, Benowitz NL, Tyndale RF. PMID: 23027621; PMCID: PMC3534190.
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    281. Tobacco use among southwestern Alaska Native people. Nicotine Tob Res. 2013 Feb; 15(2):401-6. Renner CC, Lanier AP, Lindgren B, Jensen J, Patten CA, Parascandola M, Benowitz NL, Tyndale RF, Hatsukami DK. PMID: 22949573; PMCID: PMC3612002.
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    282. Assessing secondhand smoke using biological markers. Tob Control. 2013 May; 22(3):164-71. Avila-Tang E, Al-Delaimy WK, Ashley DL, Benowitz N, Bernert JT, Kim S, Samet JM, Hecht SS. PMID: 22940677; PMCID: PMC3639350.
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    283. Nicotine intake and smoking topography in smokers with bipolar disorder. Bipolar Disord. 2012 Sep; 14(6):618-27. Williams JM, Gandhi KK, Lu SE, Steinberg ML, Benowitz NL. PMID: 22938167; PMCID: PMC3641517.
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    284. Very low nicotine content cigarettes and potential consequences on cardiovascular disease. Curr Cardiovasc Risk Rep. 2012 Dec 01; 6(6):534-541. Joel DL, Denlinger RL, Dermody SS, Hatsukami DK, Benowitz NL, Donny EC. PMID: 23264843; PMCID: PMC3525710.
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    285. Determination of tobacco smoke exposure by plasma cotinine levels in infants and children attending urban public hospital clinics. Arch Pediatr Adolesc Med. 2012 Sep 01; 166(9):851-6. Dempsey DA, Meyers MJ, Oh SS, Nguyen EA, Fuentes-Afflick E, Wu AH, Jacob P, Benowitz NL. PMID: 22566513; PMCID: PMC3997061.
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    286. Population approaches to improve diet, physical activity, and smoking habits: a scientific statement from the American Heart Association. Circulation. 2012 Sep 18; 126(12):1514-63. Mozaffarian D, Afshin A, Benowitz NL, Bittner V, Daniels SR, Franch HA, Jacobs DR, Kraus WE, Kris-Etherton PM, Krummel DA, Popkin BM, Whitsel LP, Zakai NA, American Heart Association Council on Epidemiology and Prevention, Council on Nutrition, Physical Ac. PMID: 22907934; PMCID: PMC3881293.
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    287. DRD1 associations with smoking abstinence across slow and normal nicotine metabolizers. Pharmacogenet Genomics. 2012 Jul; 22(7):551-4. Lee W, Ray R, Bergen AW, Swan GE, Thomas P, Tyndale RF, Benowitz NL, Lerman C, Conti DV. PMID: 22495174; PMCID: PMC3376177.
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    288. CYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native people. Pharmacogenet Genomics. 2012 Jun; 22(6):429-40. Binnington MJ, Zhu AZ, Renner CC, Lanier AP, Hatsukami DK, Benowitz NL, Tyndale RF. PMID: 22569203; PMCID: PMC3349071.
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    289. The exposure-dependent effects of aged secondhand smoke on endothelial function. J Am Coll Cardiol. 2012 May 22; 59(21):1908-13. Frey PF, Ganz P, Hsue PY, Benowitz NL, Glantz SA, Balmes JR, Schick SF. PMID: 22595411.
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    290. High dose transdermal nicotine for fast metabolizers of nicotine: a proof of concept placebo-controlled trial. Nicotine Tob Res. 2013 Feb; 15(2):348-54. Schnoll RA, Wileyto EP, Leone FT, Tyndale RF, Benowitz NL. PMID: 22589423; PMCID: PMC3545715.
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    291. Reproducibility of the nicotine metabolite ratio in cigarette smokers. Cancer Epidemiol Biomarkers Prev. 2012 Jul; 21(7):1105-14. St Helen G, Novalen M, Heitjan DF, Dempsey D, Jacob P, Aziziyeh A, Wing VC, George TP, Tyndale RF, Benowitz NL. PMID: 22552800; PMCID: PMC3392523.
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    292. Exposure to nicotine and carcinogens among Southwestern Alaskan Native cigarette smokers and smokeless tobacco users. Cancer Epidemiol Biomarkers Prev. 2012 Jun; 21(6):934-42. Benowitz NL, Renner CC, Lanier AP, Tyndale RF, Hatsukami DK, Lindgren B, Stepanov I, Watson CH, Sosnoff CS, Jacob P. PMID: 22490317; PMCID: PMC3444141.
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    293. Exposure and kinetics of polycyclic aromatic hydrocarbons (PAHs) in cigarette smokers. Chem Res Toxicol. 2012 Apr 16; 25(4):952-64. St Helen G, Goniewicz ML, Dempsey D, Wilson M, Jacob P, Benowitz NL. PMID: 22428611; PMCID: PMC3330130.
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    294. Adherence to varenicline among African American smokers: an exploratory analysis comparing plasma concentration, pill count, and self-report. Nicotine Tob Res. 2012 Sep; 14(9):1083-91. Buchanan TS, Berg CJ, Cox LS, Nazir N, Benowitz NL, Yu L, Yturralde O, Jacob P, Choi WS, Ahluwalia JS, Nollen NL. PMID: 22367976; PMCID: PMC3432278.
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    295. Smoking behavior and exposure to tobacco toxicants during 6 months of smoking progressively reduced nicotine content cigarettes. Cancer Epidemiol Biomarkers Prev. 2012 May; 21(5):761-9. Benowitz NL, Dains KM, Hall SM, Stewart S, Wilson M, Dempsey D, Jacob P. PMID: 22354905; PMCID: PMC3348427.
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    296. Effects of menthol on the pharmacokinetics of bupropion among Black smokers. Nicotine Tob Res. 2012 Jun; 14(6):688-93. Okuyemi KS, Faseru B, Reed GA, Cox LS, Bronars CA, Opole I, Whembolua GL, Mayo MS, Ahluwalia JS, Benowitz NL. PMID: 22318754; PMCID: PMC3356293.
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    297. Rapid smoking may not be aversive in schizophrenia. Nicotine Tob Res. 2013 Jan; 15(1):262-6. Williams JM, Gandhi KK, Lu SE, Steinberg ML, Benowitz NL. PMID: 22318691; PMCID: PMC3524052.
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    298. Bupropion for smoking cessation in African American light smokers: a randomized controlled trial. J Natl Cancer Inst. 2012 Feb 22; 104(4):290-8. Cox LS, Nollen NL, Mayo MS, Choi WS, Faseru B, Benowitz NL, Tyndale RF, Okuyemi KS, Ahluwalia JS. PMID: 22282543; PMCID: PMC3283533.
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    299. Chronic disease management approach to treating tobacco addiction: comment on "Nicotine therapy sampling to induce quit attempts among smokers unmotivated to quit". Arch Intern Med. 2011 Nov 28; 171(21):1907-9. Benowitz NL. PMID: 22123797.
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    300. Gene-centric analysis of serum cotinine levels in African and European American populations. Neuropsychopharmacology. 2012 Mar; 37(4):968-74. Hamidovic A, Goodloe RJ, Bergen AW, Benowitz NL, Styn MA, Kasberger JL, Choquet H, Young TR, Meng Y, Palmer C, Pletcher M, Kertesz S, Hitsman B, Spring B, Jorgenson E. PMID: 22089314; PMCID: PMC3280653.
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    301. Smoking cessation pharmacogenetics: analysis of varenicline and bupropion in placebo-controlled clinical trials. Neuropsychopharmacology. 2012 Feb; 37(3):641-50. King DP, Paciga S, Pickering E, Benowitz NL, Bierut LJ, Conti DV, Kaprio J, Lerman C, Park PW. PMID: 22048466; PMCID: PMC3260990.
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    302. Cannabinoid-opioid interaction in chronic pain. Clin Pharmacol Ther. 2011 Dec; 90(6):844-51. Abrams DI, Couey P, Shade SB, Kelly ME, Benowitz NL. PMID: 22048225.
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    303. Effect of nicotine on cytochrome P450 1A2 activity. Br J Clin Pharmacol. 2011 Nov; 72(5):836-8. Hukkanen J, Jacob P, Peng M, Dempsey D, Benowitz NL. PMID: 21599724; PMCID: PMC3243019.
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    304. Cardiology Rx for Change: improving clinical attention to tobacco use and secondhand smoke exposure in cardiology. Clin Cardiol. 2011 Dec; 34(12):738-43. Prochaska JJ, Benowitz NL, Glantz SA, Hudmon KS, Grossman W. PMID: 21987417; PMCID: PMC6652489.
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    305. Nicotine, carbon monoxide, and carcinogen exposure after a single use of a water pipe. Cancer Epidemiol Biomarkers Prev. 2011 Nov; 20(11):2345-53. Jacob P, Abu Raddaha AH, Dempsey D, Havel C, Peng M, Yu L, Benowitz NL. PMID: 21908725; PMCID: PMC3210932.
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    306. Sodium oxybate: updates and correction to previously published safety data. J Clin Sleep Med. 2011 Aug 15; 7(4):415-6. Wang YG, Swick TJ, Carter LP, Thorpy MJ, Benowitz NL. PMID: 21897784; PMCID: PMC3161779.
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    307. Smokeless tobacco as a nicotine delivery device: harm or harm reduction? Clin Pharmacol Ther. 2011 Oct; 90(4):491-3. Benowitz NL. PMID: 21934719.
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    308. Gender-stratified gene and gene-treatment interactions in smoking cessation. Pharmacogenomics J. 2012 Dec; 12(6):521-32. Lee W, Bergen AW, Swan GE, Li D, Liu J, Thomas P, Tyndale RF, Benowitz NL, Lerman C, Conti DV. PMID: 21808284; PMCID: PMC3208134.
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    309. Cigarette smoking, nicotine, and body weight. Clin Pharmacol Ther. 2011 Jul; 90(1):164-8. Audrain-McGovern J, Benowitz NL. PMID: 21633341; PMCID: PMC3195407.
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    310. Thirdhand tobacco smoke: emerging evidence and arguments for a multidisciplinary research agenda. Environ Health Perspect. 2011 Sep; 119(9):1218-26. Matt GE, Quintana PJ, Destaillats H, Gundel LA, Sleiman M, Singer BC, Jacob P, Benowitz N, Winickoff JP, Rehan V, Talbot P, Schick S, Samet J, Wang Y, Hang B, Martins-Green M, Pankow JF, Hovell MF. PMID: 21628107; PMCID: PMC3230406.
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    311. Shorter interpuff interval is associated with higher nicotine intake in smokers with schizophrenia. Drug Alcohol Depend. 2011 Nov 01; 118(2-3):313-9. Williams JM, Gandhi KK, Lu SE, Kumar S, Steinberg ML, Cottler B, Benowitz NL. PMID: 21596491; PMCID: PMC3655704.
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    312. Racial differences in the relationship between number of cigarettes smoked and nicotine and carcinogen exposure. Nicotine Tob Res. 2011 Sep; 13(9):772-83. Benowitz NL, Dains KM, Dempsey D, Wilson M, Jacob P. PMID: 21546441; PMCID: PMC3168241.
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    313. The threat of menthol cigarettes to U.S. public health. N Engl J Med. 2011 Jun 09; 364(23):2179-81. Benowitz NL, Samet JM. PMID: 21542737.
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    314. Do biological differences help explain tobacco-related disparities? Am J Health Promot. 2011 May-Jun; 25(5 Suppl):S8-10. Pérez-Stable EJ, Benowitz NL. PMID: 21510792.
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    315. Attitudes and practices of hookah smokers in the San Francisco Bay Area. J Psychoactive Drugs. 2011 Apr-Jun; 43(2):146-52. Ahmed B, Jacob P, Allen F, Benowitz N. PMID: 21858960.
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    316. Genetic variability of smoking persistence in African Americans. Cancer Prev Res (Phila). 2011 May; 4(5):729-34. Hamidovic A, Kasberger JL, Young TR, Goodloe RJ, Redline S, Buxbaum SG, Benowitz NL, Bergen AW, Butler KR, Franceschini N, Gharib SA, Hitsman B, Levy D, Meng Y, Papanicolaou GJ, Preis SR, Spring B, Styn MA, Tong EK, White WB, Wiggins KL, Jorgenson E. PMID: 21436384; PMCID: PMC3095514.
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    317. Active and passive cigarette smoking and acute lung injury after severe blunt trauma. Am J Respir Crit Care Med. 2011 Jun 15; 183(12):1660-5. Calfee CS, Matthay MA, Eisner MD, Benowitz N, Call M, Pittet JF, Cohen MJ. PMID: 21471091; PMCID: PMC3136993.
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    318. Association of the nicotine metabolite ratio and CHRNA5/CHRNA3 polymorphisms with smoking rate among treatment-seeking smokers. Nicotine Tob Res. 2011 Jun; 13(6):498-503. Falcone M, Jepson C, Benowitz N, Bergen AW, Pinto A, Wileyto EP, Baldwin D, Tyndale RF, Lerman C, Ray R. PMID: 21385908; PMCID: PMC3103715.
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    319. Design, baseline characteristics, and retention of African American light smokers into a randomized trial involving biological data. Trials. 2011 Jan 25; 12:22. Cox LS, Faseru B, Mayo MS, Krebill R, Snow TS, Bronars CA, Nollen NL, Choi WS, Okuyemi KS, Salzman GA, Benowitz NL, Tyndale RF, Ahluwalia JS. PMID: 21266057; PMCID: PMC3038942.
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    320. Comparison of urine cotinine and the tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and their ratio to discriminate active from passive smoking. Nicotine Tob Res. 2011 Mar; 13(3):202-8. Goniewicz ML, Eisner MD, Lazcano-Ponce E, Zielinska-Danch W, Koszowski B, Sobczak A, Havel C, Jacob P, Benowitz NL. PMID: 21330276; PMCID: PMC3045466.
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    321. Treatment of nicotine addiction: present therapeutic options and pipeline developments. Trends Pharmacol Sci. 2011 May; 32(5):281-9. Polosa R, Benowitz NL. PMID: 21256603; PMCID: PMC5564372.
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    322. Nicotine metabolite ratio predicts smoking topography and carcinogen biomarker level. Cancer Epidemiol Biomarkers Prev. 2011 Feb; 20(2):234-8. Strasser AA, Benowitz NL, Pinto AG, Tang KZ, Hecht SS, Carmella SG, Tyndale RF, Lerman CE. PMID: 21212060; PMCID: PMC3077576.
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    323. Biomarkers increase detection of active smoking and secondhand smoke exposure in critically ill patients. Crit Care Med. 2011 Jan; 39(1):40-5. Hsieh SJ, Ware LB, Eisner MD, Yu L, Jacob P, Havel C, Goniewicz ML, Matthay MA, Benowitz NL, Calfee CS. PMID: 20935560; PMCID: PMC3148017.
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    324. Determination of the nicotine metabolites cotinine and trans-3'-hydroxycotinine in biologic fluids of smokers and non-smokers using liquid chromatography-tandem mass spectrometry: biomarkers for tobacco smoke exposure and for phenotyping cytochrome P450 2A6 activity. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Feb 01; 879(3-4):267-76. Jacob P, Yu L, Duan M, Ramos L, Yturralde O, Benowitz NL. PMID: 21208832; PMCID: PMC3050598.
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    325. Cautions and warnings on the US OTC label for nicotine replacement: what's a doctor to do? Addict Behav. 2011 Apr; 36(4):327-32. Zapawa LM, Hughes JR, Benowitz NL, Rigotti NA, Shiffman S. PMID: 21220188.
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    326. Impact of smoking on cardiovascular events in patients with coronary disease receiving contemporary medical therapy (from the Treating to New Targets [TNT] and the Incremental Decrease in End Points Through Aggressive Lipid Lowering [IDEAL] trials). Am J Cardiol. 2011 Jan 15; 107(2):145-50. Frey P, Waters DD, DeMicco DA, Breazna A, Samuels L, Pipe A, Wun CC, Benowitz NL. PMID: 21129718.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    327. Urine menthol as a biomarker of mentholated cigarette smoking. Cancer Epidemiol Biomarkers Prev. 2010 Dec; 19(12):3013-9. Benowitz NL, Dains KM, Dempsey D, Havel C, Wilson M, Jacob P. PMID: 20962297; PMCID: PMC3005539.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    328. Nicotine reduction revisited: science and future directions. Tob Control. 2010 Oct; 19(5):e1-10. Hatsukami DK, Perkins KA, Lesage MG, Ashley DL, Henningfield JE, Benowitz NL, Backinger CL, Zeller M. PMID: 20876072; PMCID: PMC4618689.
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    329. Impact of smokeless tobacco products on cardiovascular disease: implications for policy, prevention, and treatment: a policy statement from the American Heart Association. Circulation. 2010 Oct 12; 122(15):1520-44. Piano MR, Benowitz NL, Fitzgerald GA, Corbridge S, Heath J, Hahn E, Pechacek TF, Howard G, American Heart Association Council on Cardiovascular Nursing. PMID: 20837898.
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    330. Urine cotinine underestimates exposure to the tobacco-derived lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in passive compared with active smokers. Cancer Epidemiol Biomarkers Prev. 2010 Nov; 19(11):2795-800. Benowitz N, Goniewicz ML, Eisner MD, Lazcano-Ponce E, Zielinska-Danch W, Koszowski B, Sobczak A, Havel C, Jacob P. PMID: 20805316; PMCID: PMC2976834.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansPHPublic Health
    331. Carbamazepine but not valproate induces CYP2A6 activity in smokers with mental illness. Cancer Epidemiol Biomarkers Prev. 2010 Oct; 19(10):2582-9. Williams JM, Gandhi KK, Benowitz NL. PMID: 20719908; PMCID: PMC2952059.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    332. Nicotine deprivation and pilot performance during simulated flight. Aviat Space Environ Med. 2010 Jul; 81(7):660-4. Mumenthaler MS, Benowitz NL, Taylor JL, Friedman L, Noda A, Yesavage JA. PMID: 20597245.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    333. Environmental and biological monitoring of exposures to PAHs and ETS in the general population. Environ Int. 2010 Oct; 36(7):763-71. Aquilina NJ, Delgado-Saborit JM, Meddings C, Baker S, Harrison RM, Jacob P, Wilson M, Yu L, Duan M, Benowitz NL. PMID: 20591483; PMCID: PMC3148021.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansPHPublic Health
    334. Higher nicotine levels in schizophrenia compared with controls after smoking a single cigarette. Nicotine Tob Res. 2010 Aug; 12(8):855-9. Williams JM, Gandhi KK, Lu SE, Kumar S, Shen J, Foulds J, Kipen H, Benowitz NL. PMID: 20584771; PMCID: PMC2910875.
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    335. Nicotine addiction. N Engl J Med. 2010 Jun 17; 362(24):2295-303. Benowitz NL. PMID: 20554984; PMCID: PMC2928221.
      View in: PubMed   Mentions: 592     Fields:    Translation:Humans
    336. Chinese 'low-tar' cigarettes do not deliver lower levels of nicotine and carcinogens. Tob Control. 2010 Oct; 19(5):374-9. Gan Q, Lu W, Xu J, Li X, Goniewicz M, Benowitz NL, Glantz SA. PMID: 20507920; PMCID: PMC2978929.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    337. Estimation of nicotine dose after low-level exposure using plasma and urine nicotine metabolites. Cancer Epidemiol Biomarkers Prev. 2010 May; 19(5):1160-6. Benowitz NL, Dains KM, Dempsey D, Yu L, Jacob P. PMID: 20447913; PMCID: PMC2867075.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansPHPublic Health
    338. What is the role of lidocaine or phenytoin in tricyclic antidepressant-induced cardiotoxicity? Clin Toxicol (Phila). 2010 May; 48(4):325-30. Foianini A, Joseph Wiegand T, Benowitz N. PMID: 20507243.
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    339. Genetic variation in nicotine metabolism predicts the efficacy of extended-duration transdermal nicotine therapy. Clin Pharmacol Ther. 2010 May; 87(5):553-7. Lerman C, Jepson C, Wileyto EP, Patterson F, Schnoll R, Mroziewicz M, Benowitz N, Tyndale RF. PMID: 20336063; PMCID: PMC3896974.
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    340. Higher serum caffeine in smokers with schizophrenia compared to smoking controls. Drug Alcohol Depend. 2010 Jul 01; 110(1-2):151-5. Gandhi KK, Williams JM, Menza M, Galazyn M, Benowitz NL. PMID: 20227198; PMCID: PMC2885547.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    341. Varenicline and pheochromocytoma. Ann Intern Med. 2010 Mar 02; 152(5):335-6. Hukkanen J, Ukkola O, Benowitz NL. PMID: 20194248.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    342. Secondhand smoke and infectious disease in adults: A global women's health concern: Comment on "Passive Smoking and Tuberculosis". Arch Intern Med. 2010 Feb 08; 170(3):292-3. Benowitz NL. PMID: 20142577.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    343. New CYP2A6 gene deletion and conversion variants in a population of Black African descent. Pharmacogenomics. 2010 Feb; 11(2):189-98. Mwenifumbo JC, Zhou Q, Benowitz NL, Sellers EM, Tyndale RF. PMID: 20136358; PMCID: PMC2922202.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    344. Effects of nicotine on cytochrome P450 2A6 and 2E1 activities. Br J Clin Pharmacol. 2010 Feb; 69(2):152-9. Hukkanen J, Jacob Iii P, Peng M, Dempsey D, Benowitz NL. PMID: 20233178; PMCID: PMC2824476.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    345. Efficacy and safety of varenicline for smoking cessation in patients with cardiovascular disease: a randomized trial. Circulation. 2010 Jan 19; 121(2):221-9. Rigotti NA, Pipe AL, Benowitz NL, Arteaga C, Garza D, Tonstad S. PMID: 20048210; PMCID: PMC4096941.
      View in: PubMed   Mentions: 115     Fields:    Translation:Humans
    346. Elimination kinetics of the tobacco-specific biomarker and lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. Cancer Epidemiol Biomarkers Prev. 2009 Dec; 18(12):3421-5. Goniewicz ML, Havel CM, Peng MW, Jacob P, Dempsey D, Yu L, Zielinska-Danch W, Koszowski B, Czogala J, Sobczak A, Benowitz NL. PMID: 19959691; PMCID: PMC2804843.
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    347. Utility and relationships of biomarkers of smoking in African-American light smokers. Cancer Epidemiol Biomarkers Prev. 2009 Dec; 18(12):3426-34. Ho MK, Faseru B, Choi WS, Nollen NL, Mayo MS, Thomas JL, Okuyemi KS, Ahluwalia JS, Benowitz NL, Tyndale RF. PMID: 19959692; PMCID: PMC2791893.
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    348. Chinese "herbal" cigarettes are as carcinogenic and addictive as regular cigarettes. Cancer Epidemiol Biomarkers Prev. 2009 Dec; 18(12):3497-501. Gan Q, Yang J, Yang G, Goniewicz M, Benowitz NL, Glantz SA. PMID: 19959701; PMCID: PMC2789338.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    349. Interlaboratory comparability of serum cotinine measurements at smoker and nonsmoker concentration levels: a round-robin study. Nicotine Tob Res. 2009 Dec; 11(12):1458-66. Bernert JT, Jacob P, Holiday DB, Benowitz NL, Sosnoff CS, Doig MV, Feyerabend C, Aldous KM, Sharifi M, Kellogg MD, Langman LJ. PMID: 19933777; PMCID: PMC3167685.
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    350. Counseling to reduce children's secondhand smoke exposure and help parents quit smoking: a controlled trial. Nicotine Tob Res. 2009 Dec; 11(12):1383-94. Hovell MF, Zakarian JM, Matt GE, Liles S, Jones JA, Hofstetter CR, Larson SN, Benowitz NL. PMID: 19875762; PMCID: PMC2784487.
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    351. Genetic influences on individual differences in nicotine glucuronidation. Twin Res Hum Genet. 2009 Oct; 12(5):507-13. Lessov-Schlaggar CN, Benowitz NL, Jacob P, Swan GE. PMID: 19803778; PMCID: PMC3202423.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    352. Prevalence of smoking assessed biochemically in an urban public hospital: a rationale for routine cotinine screening. Am J Epidemiol. 2009 Oct 01; 170(7):885-91. Benowitz NL, Schultz KE, Haller CA, Wu AH, Dains KM, Jacob P. PMID: 19713287; PMCID: PMC2765360.
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    353. Safety overview of postmarketing and clinical experience of sodium oxybate (Xyrem): abuse, misuse, dependence, and diversion. J Clin Sleep Med. 2009 Aug 15; 5(4):365-71. Wang YG, Swick TJ, Carter LP, Thorpy MJ, Benowitz NL. PMID: 19968016; PMCID: PMC2725257.
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    354. Longer term exposure to secondhand smoke and health outcomes in COPD: impact of urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. Nicotine Tob Res. 2009 Aug; 11(8):945-53. Eisner MD, Jacob P, Benowitz NL, Balmes J, Blanc PD. PMID: 19587064; PMCID: PMC2711983.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansPHPublic Health
    355. A systems biology network model for genetic association studies of nicotine addiction and treatment. Pharmacogenet Genomics. 2009 Jul; 19(7):538-51. Thomas PD, Mi H, Swan GE, Lerman C, Benowitz N, Tyndale RF, Bergen AW, Conti DV, Pharmacogenetics of Nicotine Addiction and Treatment Consortium. PMID: 19525886; PMCID: PMC6485245.
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    356. Urine nicotine metabolite concentrations in relation to plasma cotinine during low-level nicotine exposure. Nicotine Tob Res. 2009 Aug; 11(8):954-60. Benowitz NL, Dains KM, Dempsey D, Herrera B, Yu L, Jacob P. PMID: 19525206; PMCID: PMC2734286.
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    357. Genome-wide linkage of cotinine pharmacokinetics suggests candidate regions on chromosomes 9 and 11. Am J Med Genet B Neuropsychiatr Genet. 2009 Jun 05; 150B(4):554-9. He Y, Bergen AW, Hops H, Andrews JA, Tildesley E, Lessov-Schlaggar CN, Webster C, Benowitz N, Swan GE. PMID: 18785207; PMCID: PMC2693302.
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    358. Dopamine genes and nicotine dependence in treatment-seeking and community smokers. Neuropsychopharmacology. 2009 Sep; 34(10):2252-64. Bergen AW, Conti DV, Van Den Berg D, Lee W, Liu J, Li D, Guo N, Mi H, Thomas PD, Lessov-Schlaggar CN, Krasnow R, He Y, Nishita D, Jiang R, McClure JB, Tildesley E, Hops H, Tyndale RF, Benowitz NL, Lerman C, Swan GE. PMID: 19494806; PMCID: PMC3558036.
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    359. Calibrating self-reported measures of maternal smoking in pregnancy via bioassays using a Monte Carlo approach. Int J Environ Res Public Health. 2009 06; 6(6):1744-59. Dukic VM, Niessner M, Pickett KE, Benowitz NL, Wakschlag LS. PMID: 19578458; PMCID: PMC2705215.
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    360. Genetic and environmental influences on the ratio of 3'hydroxycotinine to cotinine in plasma and urine. Pharmacogenet Genomics. 2009 May; 19(5):388-98. Swan GE, Lessov-Schlaggar CN, Bergen AW, He Y, Tyndale RF, Benowitz NL. PMID: 19300303; PMCID: PMC2849278.
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    361. Impact of an indoor smoking ban on bar workers' exposure to secondhand smoke. J Occup Environ Med. 2009 May; 51(5):612-9. Bondy SJ, Zhang B, Kreiger N, Selby P, Benowitz N, Travis H, Florescu A, Greenspan NR, Ferrence R. PMID: 19369895.
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    362. Association of nicotine metabolite ratio and CYP2A6 genotype with smoking cessation treatment in African-American light smokers. Clin Pharmacol Ther. 2009 Jun; 85(6):635-43. Ho MK, Mwenifumbo JC, Al Koudsi N, Okuyemi KS, Ahluwalia JS, Benowitz NL, Tyndale RF. PMID: 19279561; PMCID: PMC3698861.
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    363. Progressive commercial cigarette yield reduction: biochemical exposure and behavioral assessment. Cancer Epidemiol Biomarkers Prev. 2009 Mar; 18(3):876-83. Benowitz NL, Dains KM, Hall SM, Stewart S, Wilson M, Dempsey D, Jacob P. PMID: 19258480; PMCID: PMC2802575.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    364. Withdrawal in adolescent light smokers following 24-hour abstinence. Nicotine Tob Res. 2009 Feb; 11(2):185-9. Rubinstein ML, Benowitz NL, Auerback GM, Moscicki AB. PMID: 19246428; PMCID: PMC2658900.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    365. Nicotine chemistry, metabolism, kinetics and biomarkers. Handb Exp Pharmacol. 2009; (192):29-60. Benowitz NL, Hukkanen J, Jacob P. PMID: 19184645; PMCID: PMC2953858.
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    366. Pharmacology of nicotine: addiction, smoking-induced disease, and therapeutics. Annu Rev Pharmacol Toxicol. 2009; 49:57-71. Benowitz NL. PMID: 18834313; PMCID: PMC2946180.
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    367. Optimal serum cotinine levels for distinguishing cigarette smokers and nonsmokers within different racial/ethnic groups in the United States between 1999 and 2004. Am J Epidemiol. 2009 Jan 15; 169(2):236-48. Benowitz NL, Bernert JT, Caraballo RS, Holiday DB, Wang J. PMID: 19019851.
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    368. Nicotine metabolic rate predicts successful smoking cessation with transdermal nicotine: a validation study. Pharmacol Biochem Behav. 2009 Mar; 92(1):6-11. Schnoll RA, Patterson F, Wileyto EP, Tyndale RF, Benowitz N, Lerman C. PMID: 19000709; PMCID: PMC2657225.
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    369. Subpicogram per milliliter determination of the tobacco-specific carcinogen metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human urine using liquid chromatography-tandem mass spectrometry. Anal Chem. 2008 Nov 01; 80(21):8115-21. Jacob P, Havel C, Lee DH, Yu L, Eisner MD, Benowitz NL. PMID: 18841944; PMCID: PMC3167662.
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    370. Gene and gene by sex associations with initial sensitivity to nicotine in nonsmokers. Behav Pharmacol. 2008 Sep; 19(5-6):630-40. Perkins KA, Lerman C, Coddington S, Jetton C, Karelitz JL, Wilson A, Jennings JR, Ferrell R, Bergen AW, Benowitz NL. PMID: 18690117; PMCID: PMC2743299.
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    371. Dopamine and opioid gene variants are associated with increased smoking reward and reinforcement owing to negative mood. Behav Pharmacol. 2008 Sep; 19(5-6):641-9. Perkins KA, Lerman C, Grottenthaler A, Ciccocioppo MM, Milanak M, Conklin CA, Bergen AW, Benowitz NL. PMID: 18690118; PMCID: PMC2717609.
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    372. A randomized trial of nicotine nasal spray in adolescent smokers. Pediatrics. 2008 Sep; 122(3):e595-600. Rubinstein ML, Benowitz NL, Auerback GM, Moscicki AB. PMID: 18762494; PMCID: PMC2744418.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    373. Smoking behavior in men hospitalized with cardiovascular disease in Korea: a cross-sectional descriptive study. Heart Lung. 2008 Sep-Oct; 37(5):366-79. Sohn M, Benowitz N, Stotts N, Christopherson D, Kim KS, Jang YS, Ahn MS, Froelicher ES. PMID: 18790337.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    374. Nicotine and postoperative management of pain. Anesth Analg. 2008 Sep; 107(3):739-41. Benowitz NL. PMID: 18713874.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    375. Rate of nicotine metabolism and withdrawal symptoms in adolescent light smokers. Pediatrics. 2008 Sep; 122(3):e643-7. Rubinstein ML, Benowitz NL, Auerback GM, Moscicki AB. PMID: 18762498; PMCID: PMC2722964.
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    376. Nicotine metabolism in pregnant and nonpregnant rabbits. Nicotine Tob Res. 2008 Aug; 10(8):1385-90. Tutka P, Dempsey DA, Jacob P, Benowitz NL, Kroetz DL. PMID: 18686186; PMCID: PMC2923225.
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    377. Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma. J Natl Cancer Inst. 2008 Aug 06; 100(15):1104-12. Xing J, Chen M, Wood CG, Lin J, Spitz MR, Ma J, Amos CI, Shields PG, Benowitz NL, Gu J, de Andrade M, Swan GE, Wu X. PMID: 18664653; PMCID: PMC2720693.
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    378. Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation. Hum Mol Genet. 2008 Sep 15; 17(18):2834-48. Conti DV, Lee W, Li D, Liu J, Van Den Berg D, Thomas PD, Bergen AW, Swan GE, Tyndale RF, Benowitz NL, Lerman C, Pharmacogenetics of Nicotine Addiction and Treatment Consortium. PMID: 18593715; PMCID: PMC2525499.
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    379. Creating and evaluating genetic tests predictive of drug response. Nat Rev Drug Discov. 2008 07; 7(7):568-74. Weiss ST, McLeod HL, Flockhart DA, Dolan ME, Benowitz NL, Johnson JA, Ratain MJ, Giacomini KM. PMID: 18587383; PMCID: PMC2682785.
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    380. Dietary supplement adverse events: report of a one-year poison center surveillance project. J Med Toxicol. 2008 Jun; 4(2):84-92. Haller C, Kearney T, Bent S, Ko R, Benowitz N, Olson K. PMID: 18570167; PMCID: PMC3550135.
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    381. Assessing dimensions of nicotine dependence: an evaluation of the Nicotine Dependence Syndrome Scale (NDSS) and the Wisconsin Inventory of Smoking Dependence Motives (WISDM). Nicotine Tob Res. 2008 Jun; 10(6):1009-20. Piper ME, McCarthy DE, Bolt DM, Smith SS, Lerman C, Benowitz N, Fiore MC, Baker TB. PMID: 18584464; PMCID: PMC2614360.
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    382. Chocolate consumption in pregnancy and reduced likelihood of preeclampsia. Epidemiology. 2008 May; 19(3):459-64. Triche EW, Grosso LM, Belanger K, Darefsky AS, Benowitz NL, Bracken MB. PMID: 18379424; PMCID: PMC2782959.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    383. Toward personalized therapy for smoking cessation: a randomized placebo-controlled trial of bupropion. Clin Pharmacol Ther. 2008 Sep; 84(3):320-5. Patterson F, Schnoll RA, Wileyto EP, Pinto A, Epstein LH, Shields PG, Hawk LW, Tyndale RF, Benowitz N, Lerman C. PMID: 18388868.
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    384. Genetic influences in the variation in renal clearance of nicotine and cotinine. Clin Pharmacol Ther. 2008 Aug; 84(2):243-7. Benowitz NL, Lessov-Schlaggar CN, Swan GE. PMID: 18388871.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    385. Neurobiology of nicotine addiction: implications for smoking cessation treatment. Am J Med. 2008 Apr; 121(4 Suppl 1):S3-10. Benowitz NL. PMID: 18342164.
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    386. Human pharmacology of a performance-enhancing dietary supplement under resting and exercise conditions. Br J Clin Pharmacol. 2008 Jun; 65(6):833-40. Haller CA, Duan M, Jacob P, Benowitz N. PMID: 18341680; PMCID: PMC2485232.
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    387. Prenatal caffeine assessment: fetal and maternal biomarkers or self-reported intake? Ann Epidemiol. 2008 Mar; 18(3):172-8. Grosso LM, Triche E, Benowitz NL, Bracken MB. PMID: 18083538; PMCID: PMC2275917.
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    388. Clinical pharmacology of nicotine: implications for understanding, preventing, and treating tobacco addiction. Clin Pharmacol Ther. 2008 Apr; 83(4):531-41. Benowitz NL. PMID: 18305452.
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    389. Determinants of salivary cotinine level: a population-based study in Brazil. Rev Saude Publica. 2007 Dec; 41(6):954-62. Figueiredo VC, Szklo M, Szklo AS, Benowitz N, Lozana JA, Casado L, Masson E, Samet J. PMID: 17992352.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    390. Gene-gene interactions between CYP2B6 and CYP2A6 in nicotine metabolism. Pharmacogenet Genomics. 2007 Dec; 17(12):1007-15. Ring HZ, Valdes AM, Nishita DM, Prasad S, Jacob P, Tyndale RF, Swan GE, Benowitz NL. PMID: 18004205.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    391. Nicotine and carcinogen exposure with smoking of progressively reduced nicotine content cigarette. Cancer Epidemiol Biomarkers Prev. 2007 Nov; 16(11):2479-85. Benowitz NL, Hall SM, Stewart S, Wilson M, Dempsey D, Jacob P. PMID: 18006940.
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    392. Mutagen sensitivity and genetic variants in nucleotide excision repair pathway: genotype-phenotype correlation. Cancer Epidemiol Biomarkers Prev. 2007 Oct; 16(10):2065-71. Lin J, Swan GE, Shields PG, Benowitz NL, Gu J, Amos CI, de Andrade M, Spitz MR, Wu X. PMID: 17932354.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    393. Secondhand smoke exposure in Mexican discotheques. Nicotine Tob Res. 2007 Oct; 9(10):1021-6. Lazcano-Ponce E, Benowitz N, Sanchez-Zamorano LM, Barbosa-Sanchez L, Valdes-Salgado R, Jacob P, Diaz R, Hernandez-Avila M. PMID: 17852765.
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    394. Cytisine for smoking cessation: a research agenda. Drug Alcohol Depend. 2008 Jan 01; 92(1-3):3-8. Etter JF, Lukas RJ, Benowitz NL, West R, Dresler CM. PMID: 17825502.
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    395. Beliefs about health, smoking, and future smoking cessation among South Korean men hospitalized for cardiovascular disease. Heart Lung. 2007 Sep-Oct; 36(5):339-47. Sohn M, Stotts NA, Benowitz N, Christopherson D, Kim KS, Jang YS, Ahn MS, Froelicher ES. PMID: 17845880.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    396. Translational research in medication development for nicotine dependence. Nat Rev Drug Discov. 2007 Sep; 6(9):746-62. Lerman C, LeSage MG, Perkins KA, O'Malley SS, Siegel SJ, Benowitz NL, Corrigall WA. PMID: 17690709.
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    397. CHRNA4 and tobacco dependence: from gene regulation to treatment outcome. Arch Gen Psychiatry. 2007 Sep; 64(9):1078-86. Hutchison KE, Allen DL, Filbey FM, Jepson C, Lerman C, Benowitz NL, Stitzel J, Bryan A, McGeary J, Haughey HM. PMID: 17768273.
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    398. Higher nicotine and carbon monoxide levels in menthol cigarette smokers with and without schizophrenia. Nicotine Tob Res. 2007 Aug; 9(8):873-81. Williams JM, Gandhi KK, Steinberg ML, Foulds J, Ziedonis DM, Benowitz NL. PMID: 17654300.
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    399. Relationship of human toenail nicotine, cotinine, and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol to levels of these biomarkers in plasma and urine. Cancer Epidemiol Biomarkers Prev. 2007 Jul; 16(7):1382-6. Stepanov I, Hecht SS, Lindgren B, Jacob P, Wilson M, Benowitz NL. PMID: 17627002.
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    400. Cigarette smoking and the personalization of irinotecan therapy. J Clin Oncol. 2007 Jul 01; 25(19):2646-7. Benowitz NL. PMID: 17563392.
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    401. CYP2B6 genotype does not alter nicotine metabolism, plasma levels, or abstinence with nicotine replacement therapy. Cancer Epidemiol Biomarkers Prev. 2007 Jun; 16(6):1312-4. Lee AM, Jepson C, Shields PG, Benowitz N, Lerman C, Tyndale RF. PMID: 17548706.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    402. Genetic and environmental sources of variation in heart rate response to infused nicotine in twins. Cancer Epidemiol Biomarkers Prev. 2007 Jun; 16(6):1057-64. Swan GE, Lessov-Schlaggar CN, Krasnow RE, Wilhelmsen KC, Jacob P, Benowitz NL. PMID: 17548663.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    403. Identification of novel CYP2A6*1B variants: the CYP2A6*1B allele is associated with faster in vivo nicotine metabolism. Clin Pharmacol Ther. 2008 Jan; 83(1):115-21. Mwenifumbo JC, Lessov-Schlaggar CN, Zhou Q, Krasnow RE, Swan GE, Benowitz NL, Tyndale RF. PMID: 17522595; PMCID: PMC2921956.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCellsCTClinical Trials
    404. Genetic nondiscrimination legislation: a critical prerequisite for pharmacogenomics data sharing. Pharmacogenomics. 2007 May; 8(5):519. Altman RB, Benowitz N, Gurwitz D, Lunshof J, Relling M, Lamba J, Wieben E, Mooney S, Giacomini K, Weiss S, Johnson JA, McLeod H, Flockhart D, Weinshilboum R, Shuldiner AR, Roden D, Krauss RM, Ratain M. PMID: 17465717.
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    405. Vaporization as a smokeless cannabis delivery system: a pilot study. Clin Pharmacol Ther. 2007 Nov; 82(5):572-8. Abrams DI, Vizoso HP, Shade SB, Jay C, Kelly ME, Benowitz NL. PMID: 17429350.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansCells
    406. Modeling the relationship of cotinine and self-reported measures of maternal smoking during pregnancy: a deterministic approach. Nicotine Tob Res. 2007 Apr; 9(4):453-65. Dukic VM, Niessner M, Benowitz N, Hans S, Wakschlag L. PMID: 17454700.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansPHPublic Health
    407. The pharmacogenetics research network: from SNP discovery to clinical drug response. Clin Pharmacol Ther. 2007 Mar; 81(3):328-45. Giacomini KM, Brett CM, Altman RB, Benowitz NL, Dolan ME, Flockhart DA, Johnson JA, Hayes DF, Klein T, Krauss RM, Kroetz DL, McLeod HL, Nguyen AT, Ratain MJ, Relling MV, Reus V, Roden DM, Schaefer CA, Shuldiner AR, Skaar T, Tantisira K, Tyndale RF, Wang L, Weinshilboum RM, Weiss ST, Zineh I, Pharmacogenetics Research Network. PMID: 17339863; PMCID: PMC5006950.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimals
    408. Urine nicotine metabolites and smoking behavior in a multiracial/multiethnic national sample of young adults. Am J Epidemiol. 2007 Apr 15; 165(8):901-10. Kandel DB, Hu MC, Schaffran C, Udry JR, Benowitz NL. PMID: 17322544.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    409. Determination of phenolic metabolites of polycyclic aromatic hydrocarbons in human urine as their pentafluorobenzyl ether derivatives using liquid chromatography-tandem mass spectrometry. Anal Chem. 2007 Jan 15; 79(2):587-98. Jacob P, Wilson M, Benowitz NL. PMID: 17222024.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    410. Prediction methods for nicotine clearance using cotinine and 3-hydroxy-cotinine spot saliva samples II. Model application. J Pharmacokinet Pharmacodyn. 2007 Feb; 34(1):23-34. Levi M, Dempsey DA, Benowitz NL, Sheiner LB. PMID: 17206525.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    411. Population pharmacokinetics of nicotine and its metabolites I. Model development. J Pharmacokinet Pharmacodyn. 2007 Feb; 34(1):5-21. Levi M, Dempsey DA, Benowitz NL, Sheiner LB. PMID: 17206524.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    412. Nicotine, cotinine, withdrawal, and craving patterns during smoking and nicotine nasal spray use: results from a pilot study with African American men. Nicotine Tob Res. 2007 Jan; 9(1):65-82. Mabry PL, Tooze JA, Moser RP, Augustson EM, Malcolm RJ, Benowitz NL. PMID: 17365738.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    413. The variability of urinary cotinine levels in young children: implications for measuring ETS exposure. Nicotine Tob Res. 2007 Jan; 9(1):83-92. Matt GE, Hovell MF, Quintana PJ, Zakarian J, Liles S, Meltzer SB, Benowitz NL. PMID: 17365739.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansPHPublic Health
    414. Cotinine levels in relation to smoking behavior and addiction in young adolescent smokers. Nicotine Tob Res. 2007 Jan; 9(1):129-35. Rubinstein ML, Thompson PJ, Benowitz NL, Shiffman S, Moscicki AB. PMID: 17365743.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    415. Nicotine intake and dose response when smoking reduced-nicotine content cigarettes. Clin Pharmacol Ther. 2006 Dec; 80(6):703-14. Benowitz NL, Jacob P, Herrera B. PMID: 17178270.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCTClinical Trials
    416. Pharmacogenomics: challenges and opportunities. Ann Intern Med. 2006 Nov 21; 145(10):749-57. Roden DM, Altman RB, Benowitz NL, Flockhart DA, Giacomini KM, Johnson JA, Krauss RM, McLeod HL, Ratain MJ, Relling MV, Ring HZ, Shuldiner AR, Weinshilboum RM, Weiss ST, Pharmacogenetics Research Network. PMID: 17116919; PMCID: PMC5006954.
      View in: PubMed   Mentions: 77     Fields:    Translation:Humans
    417. Effect of grapefruit juice on cytochrome P450 2A6 and nicotine renal clearance. Clin Pharmacol Ther. 2006 Nov; 80(5):522-30. Hukkanen J, Jacob P, Benowitz NL. PMID: 17112808.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCTClinical Trials
    418. CYP2A6 genotype and the metabolism and disposition kinetics of nicotine. Clin Pharmacol Ther. 2006 Nov; 80(5):457-67. Benowitz NL, Swan GE, Jacob P, Lessov-Schlaggar CN, Tyndale RF. PMID: 17112802.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansCTClinical Trials
    419. Evaluation of urinary trans-3'-hydroxycotinine as a biomarker of children's environmental tobacco smoke exposure. Biomarkers. 2006 Nov-Dec; 11(6):507-23. Matt GE, Quintana PJ, Liles S, Hovell MF, Zakarian JM, Jacob P, Benowitz NL. PMID: 17056471.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    420. Cotinine concentration in smokers from different countries: relationship with amount smoked and cigarette type. Cancer Epidemiol Biomarkers Prev. 2006 Oct; 15(10):1799-804. Blackford AL, Yang G, Hernandez-Avila M, Przewozniak K, Zatonski W, Figueiredo V, Avila-Tang E, Ma J, Benowitz NL, Samet JM. PMID: 17021350.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    421. Gamma-hydroxybutyrate and ethanol effects and interactions in humans. J Clin Psychopharmacol. 2006 Oct; 26(5):524-9. Thai D, Dyer JE, Benowitz NL, Haller CA. PMID: 16974199; PMCID: PMC2766839.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    422. Exposure to second-hand smoke air pollution assessed from bar patrons' urinary cotinine. Nicotine Tob Res. 2006 Oct; 8(5):701-11. Repace J, Hughes E, Benowitz N. PMID: 17008197.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    423. Determinants of the rate of nicotine metabolism and effects on smoking behavior. Clin Pharmacol Ther. 2006 Oct; 80(4):319-30. Johnstone E, Benowitz N, Cargill A, Jacob R, Hinks L, Day I, Murphy M, Walton R. PMID: 17015050.
      View in: PubMed   Mentions: 76     Fields:    Translation:Humans
    424. Menthol cigarettes, smoking cessation, atherosclerosis, and pulmonary function: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Arch Intern Med. 2006 Sep 25; 166(17):1915-22. Pletcher MJ, Hulley BJ, Houston T, Kiefe CI, Benowitz N, Sidney S. PMID: 17000950.
      View in: PubMed   Mentions: 65     Fields:    Translation:Humans
    425. Anabasine toxicity from a topical folk remedy. Clin Pediatr (Phila). 2006 Sep; 45(7):669-71. Murphy NG, Albin C, Tai W, Benowitz NL. PMID: 16928847.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    426. Guidelines on nicotine dose selection for in vivo research. Psychopharmacology (Berl). 2007 Feb; 190(3):269-319. Matta SG, Balfour DJ, Benowitz NL, Boyd RT, Buccafusco JJ, Caggiula AR, Craig CR, Collins AC, Damaj MI, Donny EC, Gardiner PS, Grady SR, Heberlein U, Leonard SS, Levin ED, Lukas RJ, Markou A, Marks MJ, McCallum SE, Parameswaran N, Perkins KA, Picciotto MR, Quik M, Rose JE, Rothenfluh A, Schafer WR, Stolerman IP, Tyndale RF, Wehner JM, Zirger JM. PMID: 16896961.
      View in: PubMed   Mentions: 389     Fields:    Translation:HumansAnimals
    427. Salivary cotinine concentration versus self-reported cigarette smoking: Three patterns of inconsistency in adolescence. Nicotine Tob Res. 2006 Aug; 8(4):525-37. Kandel DB, Schaffran C, Griesler PC, Hu MC, Davies M, Benowitz N. PMID: 16920650; PMCID: PMC2538943.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansPHPublic Health
    428. Biomarkers to assess the utility of potential reduced exposure tobacco products. Nicotine Tob Res. 2006 Aug; 8(4):600-22. Hatsukami DK, Benowitz NL, Rennard SI, Oncken C, Hecht SS. PMID: 16920658; PMCID: PMC6615727.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    429. Within-subject variation of the salivary 3HC/COT ratio in regular daily smokers: prospects for estimating CYP2A6 enzyme activity in large-scale surveys of nicotine metabolic rate. J Anal Toxicol. 2006 Jul-Aug; 30(6):386-9. Lea RA, Dickson S, Benowitz NL. PMID: 16872570.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    430. Intraindividual variability of plasma antioxidants, markers of oxidative stress, C-reactive protein, cotinine, and other biomarkers. Epidemiology. 2006 Jul; 17(4):404-12. Block G, Dietrich M, Norkus E, Jensen C, Benowitz NL, Morrow JD, Hudes M, Packer L. PMID: 16755268.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansPHPublic Health
    431. Mutagen sensitivity has high heritability: evidence from a twin study. Cancer Res. 2006 Jun 15; 66(12):5993-6. Wu X, Spitz MR, Amos CI, Lin J, Shao L, Gu J, de Andrade M, Benowitz NL, Shields PG, Swan GE. PMID: 16778168.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    432. Directly measured secondhand smoke exposure and COPD health outcomes. BMC Pulm Med. 2006 Jun 06; 6:12. Eisner MD, Balmes J, Yelin EH, Katz PP, Hammond SK, Benowitz N, Blanc PD. PMID: 16756671; PMCID: PMC1524811.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansPHPublic Health
    433. A genome-wide screen for nicotine dependence susceptibility loci. Am J Med Genet B Neuropsychiatr Genet. 2006 Jun 05; 141B(4):354-60. Swan GE, Hops H, Wilhelmsen KC, Lessov-Schlaggar CN, Cheng LS, Hudmon KS, Amos CI, Feiler HS, Ring HZ, Andrews JA, Tildesley E, Benowitz N. PMID: 16671072; PMCID: PMC2563426.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    434. Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation. Clin Pharmacol Ther. 2006 Jun; 79(6):600-8. Lerman C, Tyndale R, Patterson F, Wileyto EP, Shields PG, Pinto A, Benowitz N. PMID: 16765148.
      View in: PubMed   Mentions: 159     Fields:    Translation:Humans
    435. Female sex and oral contraceptive use accelerate nicotine metabolism. Clin Pharmacol Ther. 2006 May; 79(5):480-8. Benowitz NL, Lessov-Schlaggar CN, Swan GE, Jacob P. PMID: 16678549.
      View in: PubMed   Mentions: 213     Fields:    Translation:HumansCTClinical Trials
    436. Smoking habits, nicotine use, and congenital malformations. Obstet Gynecol. 2006 May; 107(5):1166; author reply 1168. Le Houezec J, Benowitz NL. PMID: 16648425.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    437. Characterization of the novel CYP2A6*21 allele using in vivo nicotine kinetics. Eur J Clin Pharmacol. 2006 Jun; 62(6):481-4. Al Koudsi N, Mwenifumbo JC, Sellers EM, Benowitz NL, Swan GE, Tyndale RF. PMID: 16758265.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    438. Caffeine metabolites in umbilical cord blood, cytochrome P-450 1A2 activity, and intrauterine growth restriction. Am J Epidemiol. 2006 Jun 01; 163(11):1035-41. Grosso LM, Triche EW, Belanger K, Benowitz NL, Holford TR, Bracken MB. PMID: 16641310.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    439. Impact of CYP2A6 genotype on pretreatment smoking behaviour and nicotine levels from and usage of nicotine replacement therapy. Mol Psychiatry. 2006 Apr; 11(4):400-9. Malaiyandi V, Lerman C, Benowitz NL, Jepson C, Patterson F, Tyndale RF. PMID: 16402128.
      View in: PubMed   Mentions: 81     Fields:    Translation:Humans
    440. Biomarkers to assess the utility of potential reduced exposure tobacco products. Nicotine Tob Res. 2006 Apr; 8(2):169-91. Hatsukami DK, Benowitz NL, Rennard SI, Oncken C, Hecht SS. PMID: 16766411.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansPHPublic Health
    441. Ethnic differences in nicotine metabolic rate among New Zealanders. N Z Med J. 2005 Dec 16; 118(1227):U1773. Lea R, Benowitz N, Green M, Fowles J, Vishvanath A, Dickson S, Lea M, Woodward A, Chambers G, Phillips D. PMID: 16372023.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    442. Support for previously identified alcoholism susceptibility Loci in a cohort selected for smoking behavior. Alcohol Clin Exp Res. 2005 Dec; 29(12):2108-15. Wilhelmsen KC, Swan GE, Cheng LS, Lessov-Schlaggar CN, Amos CI, Feiler HS, Hudmon KS, Ring HZ, Andrews JA, Tildesley E, Benowitz NL, Hops H. PMID: 16385180.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    443. Hemodynamic effects of ephedra-free weight-loss supplements in humans. Am J Med. 2005 Sep; 118(9):998-1003. Haller CA, Benowitz NL, Jacob P. PMID: 16164886.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCTClinical Trials