Julio Leon Incio, PhD

Title(s)Postdoctoral Scholar, Institute for Neurodegenerative Diseases
SchoolSchool of Medicine
Phone415-502-7171
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    Kysuhu University, JAPANPhD04/2016Molecular Neuroscience and Functional Genomics
    Kyushu University, JAPANMSc04/2012Biochemistry and Cell Signaling
    National University of TrujilloBSc2007Molecular Biology
    Collapse Awards and Honors
    Kyushu University2015  - 2015Kyushu University Fund
    Ministry of Education and Science Japan2009  - 2016MOMBUKAGAKUSHO Scholarship
    National University of Trujillo2014  - 2014Antonio Samanamud Romero distinction award

    Collapse Overview 
    Collapse Overview
    I am scientist trained in functional genomics, molecular biology, and biochemistry; trying to better understand the underlying mechanisms of a resilient brain in the context of aging and neurodegenerative diseases.

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Comparative profiling of cortical gene expression in Alzheimer's disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation. Sci Rep. 2017 12 19; 7(1):17762. Castillo E, Leon J, Mazzei G, Abolhassani N, Haruyama N, Saito T, Saido T, Hokama M, Iwaki T, Ohara T, Ninomiya T, Kiyohara Y, Sakumi K, LaFerla FM, Nakabeppu Y. PMID: 29259249; PMCID: PMC5736730.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimals
    2. Peripheral Elevation of a Klotho Fragment Enhances Brain Function and Resilience in Young, Aging, and α-Synuclein Transgenic Mice. Cell Rep. 2017 08 08; 20(6):1360-1371. Leon J, Moreno AJ, Garay BI, Chalkley RJ, Burlingame AL, Wang D, Dubal DB. PMID: 28793260; PMCID: PMC5816951.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    3. Human mitochondrial transcriptional factor A breaks the mitochondria-mediated vicious cycle in Alzheimer's disease. Sci Rep. 2016 11 29; 6:37889. Oka S, Leon J, Sakumi K, Ide T, Kang D, LaFerla FM, Nakabeppu Y. PMID: 27897204; PMCID: PMC5126576.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    4. Molecular pathophysiology of impaired glucose metabolism, mitochondrial dysfunction, and oxidative DNA damage in Alzheimer's disease brain. Mech Ageing Dev. 2017 01; 161(Pt A):95-104. Abolhassani N, Leon J, Sheng Z, Oka S, Hamasaki H, Iwaki T, Nakabeppu Y. PMID: 27233446.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    5. 8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions. Sci Rep. 2016 Feb 25; 6:22086. Leon J, Sakumi K, Castillo E, Sheng Z, Oka S, Nakabeppu Y. PMID: 26912170; PMCID: PMC4766534.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    6. MUTYH, an adenine DNA glycosylase, mediates p53 tumor suppression via PARP-dependent cell death. Oncogenesis. 2014 Oct 13; 3:e121. Oka S, Leon J, Tsuchimoto D, Sakumi K, Nakabeppu Y. PMID: 25310643; PMCID: PMC4216901.
      View in: PubMed   Mentions: 21  
    7. Altered expression of diabetes-related genes in Alzheimer's disease brains: the Hisayama study. Cereb Cortex. 2014 Sep; 24(9):2476-88. Hokama M, Oka S, Leon J, Ninomiya T, Honda H, Sasaki K, Iwaki T, Ohara T, Sasaki T, LaFerla FM, Kiyohara Y, Nakabeppu Y. PMID: 23595620; PMCID: PMC4128707.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansAnimals
    With one click, see people who:

    Mentor Faculty

    Offer Student Projects

    Run Clinical Trials

    Work in Global Health Equity

    See more options in the Advanced Search tab

    Julio's Networks
    Concepts (54)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (5)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCSF Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number UL1 TR000004) at the National Institutes of Health (NIH).

    We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use. This site is running Profiles RNS version UCSF-v3.1.0-1-g3264e86e on PROFILES-PWEB04.

    Copyright © The Regents of the University of California.