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Chronic degenerative failure of salivary glands can be reversed through restoring mitochondrial function. bioRxiv. 2025 Jan 02.
Li J, Tan LX, Sun B, Griffin N, Niknezhad SV, Yu C, Berthoin L, Cruz-Pacheco N, Mohabbat S, Sinada H, Efraim Y, Chen FYT, An L, Gaylord EA, Bahney CS, Lombaert IMA, Knox SM. PMID: 39803569; PMCID: PMC11722244.
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PFOA exposure induces aberrant glucose and lipid metabolism in the rat liver through the AMPK/mTOR pathway. Toxicology. 2023 07; 493:153551.
Zhang X, Ren X, Sun W, Griffin N, Wang L, Liu H. PMID: 37236338.
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1 Fields:
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Animals
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Exposure to PFOA and its novel analogs disrupts lipid metabolism in zebrafish. Ecotoxicol Environ Saf. 2023 Jul 01; 259:115020.
Sun W, Zhang X, Qiao Y, Griffin N, Zhang H, Wang L, Liu H. PMID: 37201426.
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4 Fields:
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Animals
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Neuronal-epithelial cross-talk drives acinar specification via NRG1-ERBB3-mTORC2 signaling. Dev Cell. 2022 11 21; 57(22):2550-2565.e5.
May AJ, Mattingly AJ, Gaylord EA, Griffin N, Sudiwala S, Cruz-Pacheco N, Emmerson E, Mohabbat S, Nathan S, Sinada H, Lombaert IMA, Knox SM. PMID: 36413949; PMCID: PMC9727910.
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PubMed Mentions:
7 Fields:
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HumansAnimalsCells
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Rutin ameliorates perfluorooctanoic acid-induced testicular injury in mice by reducing oxidative stress and improving lipid metabolism. Drug Chem Toxicol. 2023 Nov; 46(6):1223-1234.
Ma X, Ren X, Zhang X, Griffin N, Liu H, Wang L. PMID: 36373176.
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2 Fields:
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Animals
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iTRAQ-based quantitative proteomics analysis of Sprague-Dawley rats liver reveals perfluorooctanoic acid-induced lipid metabolism and urea cycle dysfunction. Toxicol Lett. 2022 Mar 01; 357:20-32.
Liu H, Sun W, Zhou Y, Griffin N, Faulkner S, Wang L. PMID: 34958885.
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PubMed Mentions:
9 Fields:
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AnimalsCells
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Interactions of perfluorooctanoic acid with acyl-CoA thioesterase 1 (Acot1). Comp Biochem Physiol C Toxicol Pharmacol. 2021 Dec; 250:109159.
Liu H, Cheng J, Zhou Y, Liu F, Griffin N, Faulkner S, Wang L. PMID: 34365018.
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AnimalsCells
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Tumor innervation and clinical outcome in pancreatic cancer. Sci Rep. 2021 04 01; 11(1):7390.
Ferdoushi A, Griffin N, Marsland M, Xu X, Faulkner S, Gao F, Liu H, King SJ, Denham JW, van Helden DF, Jobling P, Jiang CC, Hondermarck H. PMID: 33795769; PMCID: PMC8017010.
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29 Fields:
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HumansCells
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The neurotrophic tyrosine kinase receptor 1 (TrkA) is overexpressed in oesophageal squamous cell carcinoma. Pathology. 2021 Jun; 53(4):470-477.
Griffin N, Gao F, Jobling P, Oldmeadow C, Wills V, Walker MM, Faulkner S, Hondermarck H. PMID: 33143904.
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5 Fields:
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HumansCells
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The Receptor Tyrosine Kinase TrkA Is Increased and Targetable in HER2-Positive Breast Cancer. Biomolecules. 2020 09 17; 10(9).
Griffin N, Marsland M, Roselli S, Oldmeadow C, Attia J, Walker MM, Hondermarck H, Faulkner S. PMID: 32957504; PMCID: PMC7564775.
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PubMed Mentions:
10 Fields:
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HumansCells
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Schwann Cell Stimulation of Pancreatic Cancer Cells: A Proteomic Analysis. Front Oncol. 2020; 10:1601.
Ferdoushi A, Li X, Griffin N, Faulkner S, Jamaluddin MFB, Gao F, Jiang CC, van Helden DF, Tanwar PS, Jobling P, Hondermarck H. PMID: 32984024; PMCID: PMC7477957.
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9
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Nerve growth factor and its receptor tyrosine kinase TrkA are overexpressed in cervical squamous cell carcinoma. FASEB Bioadv. 2020 Jul; 2(7):398-408.
Faulkner S, Griffin N, Rowe CW, Jobling P, Lombard JM, Oliveira SM, Walker MM, Hondermarck H. PMID: 32676580; PMCID: PMC7354692.
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15
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The Membrane Protein Sortilin Can Be Targeted to Inhibit Pancreatic Cancer Cell Invasion. Am J Pathol. 2020 09; 190(9):1931-1942.
Gao F, Griffin N, Faulkner S, Li X, King SJ, Jobling P, Denham JW, Jiang CC, Hondermarck H. PMID: 32526166.
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14 Fields:
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Humans
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Clinicopathological Significance of Nerves in Esophageal Cancer. Am J Pathol. 2020 09; 190(9):1921-1930.
Griffin N, Rowe CW, Gao F, Jobling P, Wills V, Walker MM, Faulkner S, Hondermarck H. PMID: 32479822.
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PubMed Mentions:
10 Fields:
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Humans
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Innervation of papillary thyroid cancer and its association with extra-thyroidal invasion. Sci Rep. 2020 01 30; 10(1):1539.
Rowe CW, Dill T, Griffin N, Jobling P, Faulkner S, Paul JW, King S, Smith R, Hondermarck H. PMID: 32001748; PMCID: PMC6992619.
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PubMed Mentions:
25 Fields:
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HumansCells
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Targeting neurotrophin signaling in cancer: The renaissance. Pharmacol Res. 2018 09; 135:12-17.
Griffin N, Faulkner S, Jobling P, Hondermarck H. PMID: 30031169.
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PubMed Mentions:
49 Fields:
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HumansAnimalsCells
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The neurotrophic tyrosine kinase receptor TrkA and its ligand NGF are increased in squamous cell carcinomas of the lung. Sci Rep. 2018 05 25; 8(1):8135.
Gao F, Griffin N, Faulkner S, Rowe CW, Williams L, Roselli S, Thorne RF, Ferdoushi A, Jobling P, Walker MM, Hondermarck H. PMID: 29802376; PMCID: PMC5970205.
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19 Fields:
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Humans
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Next-generation sequencing reveals broad down-regulation of microRNAs in secondary progressive multiple sclerosis CD4+ T cells. Clin Epigenetics. 2016; 8(1):87.
Sanders KA, Benton MC, Lea RA, Maltby VE, Agland S, Griffin N, Scott RJ, Tajouri L, Lechner-Scott J. PMID: 27570566; PMCID: PMC5002332.
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PubMed Mentions:
22 Fields:
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HumansCells