Norman Oppenheimer, PhD

Title(s)Professor Emeritus, Pharmaceutical Chemistry
SchoolSchool of Pharmacy
Address513 Parnassus Avenue, MSB
San Francisco CA 94117
Phone415-476-4031
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    MERCURY 400 MHZ BROADBAND NMR SYSTEM
    NIH S10RR013040May 1, 1998 - Apr 30, 1999
    Role: Principal Investigator
    ALCOHOL DEHYDROGENASE CATALYZED SEQUENTIAL OXIDATIONS
    NIH R01GM052529Apr 1, 1995 - Mar 31, 2000
    Role: Principal Investigator
    QE 300 NMR SPECTROMETER
    NIH S10RR004789May 26, 1989 - May 25, 1990
    Role: Principal Investigator
    MECHANISM OF DOUBLE STRAND SCISSION OF DNA BY BLEOMYCIN
    NIH R01CA047764Jul 1, 1988 - Dec 31, 1991
    Role: Principal Investigator
    1986 GORDON RESEARCH CONFERENCE--ENZYMES &COENZYMES
    NIH R13GM037198Jun 29, 1986 - Dec 31, 1986
    Role: Principal Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator
    MECHANISM OF BLEOMYCIN
    NIH R01CA026272Jul 1, 1979 - Apr 30, 1986
    Role: Principal Investigator
    STRUCTURE-FUNCTION RELATIONS IN PYRIDINE COENZYMES
    NIH R01GM022982May 1, 1979 - Nov 30, 1997
    Role: Principal Investigator
    Resource for Biocomputing, Visualization, and Informatics
    NIH/NCRR P41RR001081Jun 1, 1976 - Sep 14, 2012
    Role: Co-Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Alteration in substrate specificity of horse liver alcohol dehydrogenase by an acyclic nicotinamide analog of NAD(+). DNA Repair (Amst). 2014 Nov; 23:95-100. Malver O, Sebastian MJ, Oppenheimer NJ. PMID: 25280628.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    2. Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates. PLoS One. 2012; 7(4):e34918. Egea PF, Muller-Steffner H, Kuhn I, Cakir-Kiefer C, Oppenheimer NJ, Stroud RM, Kellenberger E, Schuber F. PMID: 22529956; PMCID: PMC3329556.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    3. Mechanism of cyclizing NAD to cyclic ADP-ribose by ADP-ribosyl cyclase and CD38. J Biol Chem. 2009 Oct 02; 284(40):27629-36. Graeff R, Liu Q, Kriksunov IA, Kotaka M, Oppenheimer N, Hao Q, Lee HC. PMID: 19640843; PMCID: PMC2785691.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    4. Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase. J Biol Chem. 2009 Oct 02; 284(40):27637-45. Liu Q, Graeff R, Kriksunov IA, Jiang H, Zhang B, Oppenheimer N, Lin H, Potter BV, Lee HC, Hao Q. PMID: 19640846; PMCID: PMC2785692.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    5. CD38 induces apoptosis of a murine pro-B leukemic cell line by a tyrosine kinase-dependent but ADP-ribosyl cyclase- and NAD glycohydrolase-independent mechanism. Int Immunol. 2006 Jul; 18(7):1029-42. Lund FE, Muller-Steffner H, Romero-Ramirez H, Moreno-García ME, Partida-Sánchez S, Makris M, Oppenheimer NJ, Santos-Argumedo L, Schuber F. PMID: 16720618.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    6. Activation of T cell calcium influx by the second messenger ADP-ribose. J Biol Chem. 2006 Feb 03; 281(5):2489-96. Gasser A, Glassmeier G, Fliegert R, Langhorst MF, Meinke S, Hein D, Krüger S, Weber K, Heiner I, Oppenheimer N, Schwarz JR, Guse AH. PMID: 16316998.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    7. CD38 controls ADP-ribosyltransferase-2-catalyzed ADP-ribosylation of T cell surface proteins. J Immunol. 2005 Mar 15; 174(6):3298-305. Krebs C, Adriouch S, Braasch F, Koestner W, Leiter EH, Seman M, Lund FE, Oppenheimer N, Haag F, Koch-Nolte F. PMID: 15749861.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    8. Extracellular NAD+ regulates intracellular free calcium concentration in human monocytes. Biochem J. 2004 Sep 15; 382(Pt 3):849-56. Gerth A, Nieber K, Oppenheimer NJ, Hauschildt S. PMID: 15233622; PMCID: PMC1133960.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    9. Regulation of dendritic cell trafficking by the ADP-ribosyl cyclase CD38: impact on the development of humoral immunity. Immunity. 2004 Mar; 20(3):279-91. Partida-Sánchez S, Goodrich S, Kusser K, Oppenheimer N, Randall TD, Lund FE. PMID: 15030772.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    10. CD38 is expressed as noncovalently associated homodimers on the surface of murine B lymphocytes. Eur J Biochem. 2004 Mar; 271(5):1025-34. Moreno-García ME, Partida-Sánchez S, Primack J, Sumoza-Toledo A, Muller-Steffner H, Schuber F, Oppenheimer N, Lund FE, Santos-Argumedo L. PMID: 15009214.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    11. Chemotaxis and calcium responses of phagocytes to formyl peptide receptor ligands is differentially regulated by cyclic ADP ribose. J Immunol. 2004 Feb 01; 172(3):1896-906. Partida-Sánchez S, Iribarren P, Moreno-García ME, Gao JL, Murphy PM, Oppenheimer N, Wang JM, Lund FE. PMID: 14734775.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    12. Fluorometric studies of ligand-induced conformational changes of CD38. Biochim Biophys Acta. 2003 Nov 03; 1652(1):17-26. Lacapère JJ, Boulla G, Lund FE, Primack J, Oppenheimer N, Schuber F, Deterre P. PMID: 14580993.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    13. Mechanism of nicotinamide inhibition and transglycosidation by Sir2 histone/protein deacetylases. J Biol Chem. 2003 Dec 19; 278(51):50985-98. Jackson MD, Schmidt MT, Oppenheimer NJ, Denu JM. PMID: 14522996.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansCells
    14. Novel hydrolysis-resistant analogues of cyclic ADP-ribose: modification of the "northern" ribose and calcium release activity. Biochemistry. 2002 May 28; 41(21):6744-51. Guse AH, Cakir-Kiefer C, Fukuoka M, Shuto S, Weber K, Bailey VC, Matsuda A, Mayr GW, Oppenheimer N, Schuber F, Potter BV. PMID: 12022878.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    15. Reactions of Charged Substrates. 8. The Nucleophilic Substitution Reactions of (4-Methoxybenzyl)dimethylsulfonium Chloride. J Org Chem. 1997 Feb 07; 62(3):540-551. Buckley N, Oppenheimer NJ. PMID: 11671447.
      View in: PubMed   Mentions: 3     Fields:    
    16. Reactions of Charged Substrates. 6. The Methoxymethyl Carbenium Ion Problem. 1. A Semiempirical Study of the Kinetic and Thermodynamic Stabilities of Linear and Cyclic Oxo- and Thiocarbenium Ions Generated from Pyridinium and Dimethylanilinium Ions. J Org Chem. 1996 Nov 15; 61(23):8039-8047. Buckley N, Oppenheimer NJ. PMID: 11667787.
      View in: PubMed   Mentions:    Fields:    
    17. Reactions of Charged Substrates. 7. The Methoxymethyl Carbenium Ion Problem. 2. A Semiempirical Study of the Kinetic and Thermodynamic Stabilities of Linear and Cyclic Oxo- and Thiocarbenium Ions Generated from Aldehyde Hydrates, Hemiacetals, Acetals, and Methyl Ribosides and Glucosides. J Org Chem. 1996 Nov 15; 61(23):8048-8062. Buckley N, Oppenheimer NJ. PMID: 11667788.
      View in: PubMed   Mentions: 4     Fields:    
    18. Reactions of Charged Substrates. 5. The Solvolysis and Sodium Azide Substitution Reactions of Benzylpyridinium Ions in Deuterium Oxide. J Org Chem. 1996 Oct 18; 61(21):7360-7372. Buckley N, Oppenheimer NJ. PMID: 11667662.
      View in: PubMed   Mentions: 5     Fields:    
    19. Reactions of Charged Substrates. 4. The Gas-Phase Dissociation of (4-Substituted benzyl)dimethylsulfoniums and -pyridiniums. J Org Chem. 1996 Apr 19; 61(8):2753-2762. Buckley N, Maltby D, Burlingame AL, Oppenheimer NJ. PMID: 11667109.
      View in: PubMed   Mentions: 2     Fields:    
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