Eric Verdin, MD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address3333 California Street, #435N
San Francisco CA 94118
ORCID ORCID Icon0000-0003-3703-3183 Additional info
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    Collapse Research 
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    Cellular senescence and Associated Lysosomal Dysfunction in Immune Aging
    NIH U01AI180158Mar 1, 2024 - Feb 28, 2029
    Role: Principal Investigator
    The University of Southern California and Buck Institute Nathan Shock Center
    NIH P30AG068345Sep 15, 2020 - May 31, 2025
    Role: Principal Investigator
    Genetic dissection of trait variation between long-diverged mouse species
    NIH R01NS116992Sep 30, 2019 - Jun 30, 2025
    Role: Co-Principal Investigator
    Molecular Mechanisms of HIV Latency
    NIH R01DA041742Apr 15, 2016 - Jun 30, 2022
    Role: Principal Investigator
    Novel model for HIV Latency in Oral Primary Lymphoid Tissues
    NIH R01DE026010Apr 1, 2016 - Jan 31, 2021
    Role: Principal Investigator
    Lysine Malonylation and SIRT5 in Epigenetic Regulation
    NIH R21AG051111Jan 1, 2016 - Dec 31, 2017
    Role: Principal Investigator
    Identification of HIV latency biomarkers with a dual fluorescence reporter HIV
    NIH R01AI117864Mar 1, 2015 - Feb 28, 2021
    Role: Principal Investigator
    Martin Delaney Collaboratory to Eradicate HIV-1 Infection
    NIH U19AI096113Jul 8, 2011 - Jun 30, 2016
    Role: Co-Investigator
    Novel Model for HIV Latency in Primary Memory T Cells
    NIH DP1DA031126Sep 30, 2010 - Feb 29, 2016
    Role: Principal Investigator
    Epigenetic regulation of HIV latency
    NIH R01DA030216Jul 1, 2010 - Feb 29, 2016
    Role: Principal Investigator
    Reversible Mitochondrial Protein Acetylation and Metabolic Regulation
    NIH R24DK085610Jun 1, 2010 - Oct 31, 2020
    Role: Principal Investigator
    Role of HDAC7 in T-cell Development
    NIH R56AI076664Mar 1, 2010 - Feb 28, 2012
    Role: Principal Investigator
    Regulation of HIV transcription and replication by SDF-1gamma
    NIH R21AI065255Jul 1, 2005 - Jun 30, 2007
    Role: Principal Investigator
    Molecular Mechanisms of HIV Post-Integration Latency
    NIH P01AI058708Sep 30, 2004 - Jan 31, 2010
    Role: Principal Investigator
    A New In Vitro Model for HIV Latency
    NIH R21AI054141Jun 1, 2003 - May 31, 2005
    Role: Principal Investigator
    STRUCTURE-BASED DESIGN PARADIGM:HIV Tat.PCAF INHIBITORS
    NIH P01GM066531Aug 10, 2002 - Jul 31, 2010
    Role: Co-Investigator
    MODULATION OF CD8 T CELL FUNCTION BY HIV ENVELOPE PROTEI
    NIH R01HL063646Aug 16, 1999 - Jul 31, 2004
    Role: Principal Investigator
    MODULATION OF T CELL FUNCTIONS BY HIV1 TAT
    NIH R01AI040847Sep 1, 1997 - Aug 31, 2003
    Role: Principal Investigator
    Role of Chromatin in HIV Transcriptional Regulation
    NIH R01GM051671May 1, 1995 - Nov 30, 2012
    Role: Principal Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator
    California National Primate Research Center
    NIH P51RR000169Jun 1, 1975 - Apr 30, 2015
    Role: Co-Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The longevity gene APOE2 enhances pericyte function and reduces lipid droplets. Brain. 2026 Sep 16. Reskiawan A Kadir R, Bons J, Vega Hormazabal G, Vadhana Ashok Kumaar P, Gerónimo-Olvera C, Tshilenge KT, Pihán P, Galicia Aguirre C, Schneider K, Roberts A, Ambrose BD, Lerner C, Devanney NA, Sandholm AM, Hady M, Alderfer S, Hetz C, Furman D, Gerencser AA, Verdin E, Schilling B, Ellerby LM. PMID: 42744302.
      View in: PubMed   Mentions:
    2. Author Correction: Trained immunity links hematopoietic stem cell aging to aging-associated inflammation. Nat Aging. 2026 Sep; 6(9):2038. Mu WC, Barthez M, Feng Y, Chen Y, Wang CL, Huang JY, Li J, Lanhart P, Tsuei KC, Kim YJ, Verdin E, Netea MG, Chen D. PMID: 42587143; PMCID: PMC13577910.
      View in: PubMed   Mentions:
    3. Novel insights into tomato leaf curl New Delhi virus introduction and evolution in Southeastern France using an advanced long-read sequencing workflow. PLoS Pathog. 2026 Aug; 22(8):e1014463. Patthamapornsirikul A, Golyaev V, Verdin E, Goillon C, Boolell H, Dierickx S, Wipf-Scheibel C, Girardot G, Dumon W, Cleemput S, Deforche K, Vanderschuren H, Desbiez C. PMID: 42566464; PMCID: PMC13475965.
      View in: PubMed   Mentions:    Fields:    
    4. Trained immunity links hematopoietic stem cell aging to aging-associated inflammation. Nat Aging. 2026 Jul 16. Mu WC, Barthez M, Feng Y, Chen Y, Wang CL, Huang JY, Li J, Lanhart P, Tsuei KC, Kim YJ, Verdin E, Netea MG, Chen D. PMID: 42463951.
      View in: PubMed   Mentions:    Fields:    
    5. Author Correction: Regulation of urea cycle by reversible high-stoichiometry lysine succinylation. Nat Metab. 2026 Jun; 8(6):1440. Zhang R, Fang J, Xie X, Carrico C, Meyer JG, Wei L, Bons J, Rose J, Riley R, Kwok R, Ashok Kumaar PV, Zhang Y, Bielska O, He W, Nishida Y, Liu X, Locasale JW, Schilling B, Verdin E. PMID: 42174185.
      View in: PubMed   Mentions: 1     Fields:    
    6. Replacement-Based Ageing Interventions for Systemic Rejuvenation: Shaping Longevity Science and Clinical Directions. Aging Cell. 2026 May; 25(5):e70516. Olaisen BF, Gladyshev VN, Zhang B, Atala A, Loh KM, Gorbunova V, Rando TA, Wyss-Coray T, Verdin E, Zhavoronkov A, Scheibye-Knudsen M, Lore S, Bakula D. PMID: 42053420; PMCID: PMC13127223.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    7. Exceptional Longevity Modifying Allele APOE2 Promotes DNA Signaling Pathways Resisting Cellular Senescence in Human Neurons. Aging Cell. 2026 May; 25(5):e70494. Gerónimo-Olvera C, Scheeler SM, Aguirre CG, Vega-Hormazabal G, Garcia D, Wu L, Murad N, Schneider K, Wilson KA, Markov NT, Song S, Simons J, Gerencser AA, Parlan E, Mooney SD, Verdin E, Campisi J, Tracy TE, Furman D, Melov S, Ellerby LM. PMID: 42103698; PMCID: PMC13156074.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    8. Ketone ester supplementation in aged mice reduces activation of B cell subsets. bioRxiv. 2026 Apr 22. Adkisson-Floro A, Tiwari R, Nomura M, Riley RR, Kwok R, Sellegounder D, Khalid MM, Kasler HG, Newman JC, Verdin E. PMID: 42079244; PMCID: PMC13131667.
      View in: PubMed   Mentions:
    9. p21+TREM2+ senescent macrophages fuel inflammaging and metabolic dysfunction-associated steatotic liver disease. Nat Aging. 2026 Apr; 6(4):792-815. Salladay-Perez IA, Avila I, Estrada L, Alexandru AC, Ponce C, Dhingra A, Torres G, Deng CY, Hegde R, Gensheimer J, Kale A, Heckenbach I, Hui S, Edillor C, Soto JA, Napior AJ, Little I, Larsen M, Rose J, Farahi L, Lopez Gonzalez EDJ, Krieger MR, Chowdhury K, Sharma M, Jiang Y, Williams K, Scheibye-Knudsen M, Koehler CM, Meyer JG, Mack JJ, Brenner C, Bensinger SJ, Lagger C, de Magalhães JP, Schilling B, Singh R, Verdin E, Lusis AJ, Covarrubias AJ. PMID: 41991686; PMCID: PMC13099426.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    10. Toward actionable interventions in human aging (12th ARDD meeting, 2025). Aging (Albany NY). 2026 Apr 06; 18(1):282-302. Dekan A, Lore S, Yoon YE, Sjöholm A, Tyshkovskiy A, Terskikh A, Cuervo AM, Georgievskaya A, Heinz A, Seluanov A, Adams A, Tsai AP, Murray A, Brunet A, Harten AMV, Spier A, Shenhar B, Pedersen BK, Clasen B, Schumacher B, Kennedy BK, Suetta C, Volbracht C, Kuppe C, Cookson C, Ewald CY, Banila C, Cai D, Valenzano DR, Lamming DW, Rudnic E, Samra EB, Teeling E, Verdin E, Fang EF, Fagagna FDD, Galkin F, Zmudze G, Jasper H, Jang IH, Han JJ, Justice J, Hoeijmakers JHJ, Ramos JMP, Lemaitre JM, Aerssens J, Betts-LaCroix J, Newman JC, Belmonte JCI, Kawamura K, Schaal KM, Egerton K, Abdelmohsen K, Fortney K, Hartenstein L, Niedernhofer L, Katsimpardi L, Melton L, Knudsen LB, Ferrucci L, Sylow L, Demaria M, Schafer MJ, Guasch-Ferré M, Borch-Jensen M, Kholin M, Antonov M, Levitt M, Deleidi M, Merad M, Meldal M, Topors M, Venkatesan M, LeBrasseur NK, Anzinger N, Fedichev P, Kohlhaas P, Mullen PJ, Singhal P, Cabo R, Houtkooper RH, Montgomery R, Smith R, Rosenzweig-Lipson S, Jakimov S, Horvath S, Austad S, Rando TA, White T, Zuber T, Rozmaric T, Wyss-Coray T, Tammela T, Gladyshev VN, Sinatti VVC, Wang W, Harborne W, Liu X, Wang XL, Suh Y, Lee Y, Koch Z, Zhavoronkov A, Scheibye-Knudsen M, Bakula D. PMID: 41944812; PMCID: PMC13285953.
      View in: PubMed   Mentions:    Fields:    
    11. Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV. Aging (Albany NY). 2026 Feb 08; 18(1):5-29. Tomusiak A, Lore S, Scheibye-Knudsen M, Verdin E. PMID: 41747291; PMCID: PMC13285955.
      View in: PubMed   Mentions:    Fields:    
    12. Regulation of virion production by the ORF8 signal peptide across SARS-CoV-2 variants. bioRxiv. 2026 Feb 03. Khalid MM, Chen IP, Soveg FS, Taha TY, Tabata T, Suryawanshi RK, Syed AM, Ciling A, McCavitt-Malvido M, Schulze-Gahmen U, Hayashi J, Kim IJ, Fong SW, Batra J, Kumar GR, Renia L, Ng LF, Krogan NJ, Doudna JA, Verdin E, Ott M. PMID: 41676649; PMCID: PMC12889891.
      View in: PubMed   Mentions:
    13. Author Correction: Effect of the mitophagy inducer urolithin A on age-related immune decline: a randomized, placebo-controlled trial. Nat Aging. 2026 Feb; 6(2):463. Denk D, Singh A, Kasler HG, D'Amico D, Rey J, Alcober-Boquet L, Gorol JM, Steup C, Tiwari R, Kwok R, Argüello RJ, Faitg J, Sprinzl K, Zeuzem S, Nekljudova V, Loibl S, Verdin E, Rinsch C, Greten FR. PMID: 41491872; PMCID: PMC12920124.
      View in: PubMed   Mentions:    Fields:    
    14. Multi-Omics Analysis of Human Blood Cells Reveals Unique Features of Age-Associated Type 2 CD8 Memory T Cells. Aging Cell. 2026 Feb; 25(2):e70393. Matsui H, Cervantes M, Khalid MM, Tomusiak A, Dwaraka V, Landgrave-Gomez J, Kumaar PVA, Chen Q, Lasky-Su J, Stone J, Tiwari R, Kwok R, Ichikawa S, Ambrose BD, Riley RR, Hormazabal GV, Adkisson-Floro A, Alexandru AC, Smith R, Schilling B, Kasler HG, Verdin E. PMID: 41622514; PMCID: PMC12862018.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    15. Multi-omics Analysis of Human Blood Cells Reveals Unique Features of Age-associated Type2 CD8 Memory T cells. bioRxiv. 2026 Jan 07. Matsui H, Cervantes M, Khalid MM, Tomusiak A, Dwaraka V, Landgrave-Gomez J, Ashok Kumaar PV, Chen Q, Lasky-Su J, Stone J, Tiwari R, Kwok R, Ichikawa S, Ambrose BD, Riley RR, Hormazabal GV, Floro A, Alexandru AC, Smith R, Schilling B, Kasler HG, Verdin E. PMID: 41542640; PMCID: PMC12803054.
      View in: PubMed   Mentions:
    16. CD38 Inhibition Ameliorates Age-Related CognitiveDecline via a Choroid Plexus-Cerebrospinal Fluid-Hippocampus Axis. Res Sq. 2026 Jan 06. Verdin E, Fang J, Riley R, Schneider K, Perrone R, Kumaar P, King C, Kauwe G, Roberts A, Hormazabal GV, Zhang Y, Millard E, Liu X, Jara W, Aguirre CG, Baker H, Murad N, Ambrose B, Tran T, Martin N, Zhang R, Sellegounder D, Melov S, Furman D, Tracy T, Gerencser A, Schilling B, Ellerby L. PMID: 41542058; PMCID: PMC12803333.
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    17. Past, present and future perspectives on the science of aging. Nat Aging. 2026 Jan; 6(1):6-22. Ambrosio F, Artyomov MN, Austad SN, Barzilai N, Belmonte JCI, Belsky DW, Benayoun BA, Brunet A, Dönertas HM, Dubal DB, Fang EF, Feige JN, Fried LP, Furman D, Gao X, Gladyshev VN, Gorbunova V, Gorospe M, Han JJ, Hansson O, Hara E, Horvath S, Ip NY, Kuchel GA, Kaeberlein M, Lamming DW, Levy BR, Liu GH, Lee J, Moffitt TE, Minamino T, Partridge L, Raina P, Rando TA, Rowe JW, Schwartz M, Scott AJ, Sierra F, Sinclair DA, Teunissen CE, Vellas B, Verdin E, Walker KA, Webb AE, Wyss-Coray T, Xu M, Yu JT, Zhavoronkov A, Aman Y, Kriebs A, Ren Q, Walters H, Thuault S. PMID: 41566049.
      View in: PubMed   Mentions: 2     Fields:    
    18. Author Correction: Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain. EMBO J. 2026 Jan; 45(2):633-635. Dorr A, Kiermer V, Pedal A, Rackwitz HR, Henklein P, Schubert U, Zhou MM, Verdin E, Ott M. PMID: 41402516; PMCID: PMC12811238.
      View in: PubMed   Mentions:    Fields:    
    19. Editorial Expression of Concern to: HDAC5 is required for maintenance of pericentric heterochromatin, and controls cell-cycle progression and survival of human cancer cells. Cell Death Differ. 2025 Nov; 32(11):2175. Peixoto P, Castronovo V, Matheus N, Polese C, Peulen O, Gonzalez A, Boxus M, Verdin E, Thiry M, Dequiedt F, Mottet D. PMID: 40790254; PMCID: PMC12572328.
      View in: PubMed   Mentions:    Fields:    
    20. Effect of the mitophagy inducer urolithin A on age-related immune decline: a randomized, placebo-controlled trial. Nat Aging. 2025 Nov; 5(11):2309-2322. Denk D, Singh A, Kasler HG, D'Amico D, Rey J, Alcober-Boquet L, Gorol JM, Steup C, Tiwari R, Kwok R, Argüello RJ, Faitg J, Sprinzl K, Zeuzem S, Nekljudova V, Loibl S, Verdin E, Rinsch C, Greten FR. PMID: 41174221; PMCID: PMC12618261.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    21. Pathogenic tau inhibits synaptic plasticity by blocking eIF4B-mediated local protein synthesis. bioRxiv. 2025 Sep 12. Kauwe G, Lokitiyakul D, Wong IL, Schneider K, Sridhar V, Sellegounder D, Ngwala YY, Yao L, Chen JH, Pareja-Navarro KA, Nana AL, Spina S, Seeley WW, Grinberg LT, Verdin E, Furman D, Karch CM, Gan L, Tracy TE. PMID: 41279029; PMCID: PMC12635980.
      View in: PubMed   Mentions:
    22. Emerging strategies, applications and challenges of targeting NAD+ in the clinic. Nat Aging. 2025 Sep; 5(9):1704-1731. Zhang J, Wang HL, Lautrup S, Nilsen HL, Treebak JT, Watne LO, Selbæk G, Wu LE, Omland T, Pirinen E, Cheung TC, Wang J, Ziegler M, Tysnes OB, Zapata-Pérez R, Bruzzone S, Canto C, Deleidi M, Janssens GE, Houtkooper RH, Scheibye-Knudsen M, Koshizaka M, Yokote K, Verdin E, Bohr VA, Tzoulis C, Sinclair DA, Fang EF. PMID: 40926126.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    23. Multiplexed Targeted Spatial Mass Spectrometry Imaging Assays to monitor lipids and NAD + metabolites in CD38 knockout mice exhibiting improved metabolism. bioRxiv. 2025 Jun 30. Schurman CA, Bons J, Ashok Kumaar PV, Fang J, Roberts A, Hormazabal GV, Riley RR, Tao N, Verdin E, Schilling B. PMID: 40501674; PMCID: PMC12154796.
      View in: PubMed   Mentions:
    24. Multiplexed Targeted Spatial Mass Spectrometry Imaging Assays to monitor lipids and NAD+ metabolites in CD38 knockout mice exhibiting improved metabolism. Res Sq. 2025 Jun 16. Schilling B, Schurman C, Bons J, Kumaar P, Fang J, Roberts A, Hormazabal G, Riley R, Tao N, Verdin E. PMID: 40585256; PMCID: PMC12204368.
      View in: PubMed   Mentions:
    25. Accumulation of SA-βGal-High Cells in Human Naïve T Cell Compartments Reveals a Stress-Adapted, Senescent-Like State. bioRxiv. 2025 Jun 14. Alexandru AC, Hormazabal GV, Matsui H, Kasler H, Lore S, Aguirre CG, Roberts A, Heckenbach IJ, Tiwari R, Kwok R, Becker S, Verdin E. PMID: 40661537; PMCID: PMC12259081.
      View in: PubMed   Mentions:
    26. Digital biomarkers of ageing for monitoring physiological systems in community-dwelling adults. Lancet Healthy Longev. 2025 06; 6(6):100725. Lu JK, Wang W, Mahadzir MDA, Poganik JR, Moqri M, Herzog C, Verdin E, Sebastiano V, Gladyshev VN, Maier AB, Biomarkers of Aging Consortium. PMID: 40517785.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    27. Acute Nicotinamide Adenine Dinucleotide Supplementation via Nicotinamide Mononucleotide Does Not Rescue Functional Impairment in a Lipopolysaccharide-induced Delirium Mouse Model. J Gerontol A Biol Sci Med Sci. 2025 06 10; 80(7). Chui MKK, Ashok Kumaar PV, Schilling B, Verdin E, Newman JC. PMID: 40445730; PMCID: PMC12239633.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    28. Multi-Omics Analysis Reveals Biomarkers That Contribute to Biological Age Rejuvenation in Response to Single-Blinded Randomized Placebo-Controlled Therapeutic Plasma Exchange. Aging Cell. 2025 08; 24(8):e70103. Fuentealba M, Kiprov D, Schneider K, Mu WC, Kumaar PA, Kasler H, Burton JB, Watson M, Halaweh H, King CD, Yüksel ZS, Roska-Pamaong C, Schilling B, Verdin E, Furman D. PMID: 40424097; PMCID: PMC12341816.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    29. Outbreak of Cucumber Mosaic Virus Subgroup IB in Pepper from the Espelette Area (Basque Country, Southwestern France) and First Report of Five Taxa as Natural Hosts of CMV. Plant Dis. 2025 May; 109(5):983-987. Gaudin J, Piry S, Wipf-Scheibel C, Szadkowski M, Desbiez C, Nguyen E, Dumeaux P, Berthier K, Schoeny A, Girardot G, Hirsch J, Verdin E, Lepage E, Gognalons P, Troulet C, Moury B, Rimbaud L. PMID: 39636285.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    30. Replacement as an aging intervention. Nat Aging. 2025 May; 5(5):750-764. Lore S, Poganik JR, Atala A, Church G, Gladyshev VN, Scheibye-Knudsen M, Verdin E. PMID: 40341243; PMCID: PMC12871541.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    31. From geroscience to precision geromedicine: Understanding and managing aging. Cell. 2025 Apr 17; 188(8):2043-2062. Kroemer G, Maier AB, Cuervo AM, Gladyshev VN, Ferrucci L, Gorbunova V, Kennedy BK, Rando TA, Seluanov A, Sierra F, Verdin E, López-Otín C. PMID: 40250404; PMCID: PMC12037106.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansAnimals
    32. Accelerating the promise of geroscience through The Academy of Health & Lifespan Research. Nat Aging. 2025 Apr; 5(4):529-531. Barzilai N, Starr R, Verdin E, Niedernhofer LJ, Bertram A, Lithgow GJ, Maier AB, Academy of Health & Lifespan Research. PMID: 40055476.
      View in: PubMed   Mentions:    Fields:    
    33. The time is now: accounting for time-of-day effects to improve reproducibility and translation of metabolism research. Nat Metab. 2025 Mar; 7(3):454-468. Deota S, Pendergast JS, Kolthur-Seetharam U, Esser KA, Gachon F, Asher G, Dibner C, Benitah SA, Escobar C, Muoio DM, Zhang EE, Hotamisligil GS, Bass J, Takahashi JS, Rabinowitz JD, Lamia KA, de Cabo R, Kajimura S, Longo VD, Xu Y, Lazar MA, Verdin E, Zierath JR, Auwerx J, Drucker DJ, Panda S. PMID: 40097742; PMCID: PMC12584160.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    34. Ketogenic Diet Reduces Age-Induced Chronic Neuroinflammation in Mice. Aging Biol. 2024; 2. Nomura M, Murad NF, Madhavan SS, Mu WC, Eap B, Garcia TY, Aguirre CG, Verdin E, Ellerby L, Furman D, Newman JC. PMID: 39697898; PMCID: PMC11654834.
      View in: PubMed   Mentions: 2  
    35. β-hydroxybutyrate is a metabolic regulator of proteostasis in the aged and Alzheimer disease brain. Cell Chem Biol. 2025 Jan 16; 32(1):174-191.e8. Madhavan SS, Roa Diaz S, Peralta S, Nomura M, King CD, Ceyhan KE, Lin A, Bhaumik D, Foulger AC, Shah S, Blade T, Gray W, Chamoli M, Eap B, Panda O, Diaz D, Garcia TY, Stubbs BJ, Ulrich SM, Lithgow GJ, Schilling B, Verdin E, Chaudhuri AR, Newman JC. PMID: 39626664; PMCID: PMC11741930.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    36. Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity. Aging (Albany NY). 2024 10 16; 16(20):12955-12976. Lyu YX, Fu Q, Wilczok D, Ying K, King A, Antebi A, Vojta A, Stolzing A, Moskalev A, Georgievskaya A, Maier AB, Olsen A, Groth A, Simon AK, Brunet A, Jamil A, Kulaga A, Bhatti A, Yaden B, Pedersen BK, Schumacher B, Djordjevic B, Kennedy B, Chen C, Huang CY, Correll CU, Murphy CT, Ewald CY, Chen D, Valenzano DR, Soldacki D, Erritzoe D, Meyer D, Sinclair DA, Chini EN, Teeling EC, Morgen E, Verdin E, Vernet E, Pinilla E, Fang EF, Bischof E, Mercken EM, Finger F, Kuipers F, Pun FW, Gyülveszi G, Civiletto G, Zmudze G, Blander G, Pincus HA, McClure J, Kirkland JL, Peyer J, Justice JN, Vijg J, Gruhn JR, McLaughlin J, Mannick J, Passos J, Baur JA, Betts-LaCroix J, Sedivy JM, Speakman JR, Shlain J, von Maltzahn J, Andreasson KI, Moody K, Palikaras K, Fortney K, Niedernhofer LJ, Rasmussen LJ, Veenhoff LM, Melton L, Ferrucci L, Quarta M, Koval M, Marinova M, Hamalainen M, Unfried M, Ringel MS, Filipovic M, Topors M, Mitin N, Roy N, Pintar N, Barzilai N, Binetti P, Singh P, Kohlhaas P, Robbins PD, Rubin P, Fedichev PO, Kamya P, Muñoz-Canoves P, de Cabo R, Faragher RGA, Konrad R, Ripa R, Mansukhani R, Büttner S, Wickström SA, Brunemeier S, Jakimov S, Luo S, Rosenzweig-Lipson S, Tsai SY, Dimmeler S, Rando TA, Peterson TR, Woods T, Wyss-Coray T, Finkel T, Strauss T, Gladyshev VN, Longo VD, Dwaraka VB, Gorbunova V, Acosta-Rodríguez VA, Sorrentino V, Sebastiano V, Li W, Suh Y, Zhavoronkov A, Scheibye-Knudsen M, Bakula D. PMID: 39418098; PMCID: PMC11552646.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    37. Deep learning assessment of senescence-associated nuclear morphologies in mammary tissue from healthy female donors to predict future risk of breast cancer: a retrospective cohort study. Lancet Digit Health. 2024 10; 6(10):e681-e690. Heckenbach I, Powell M, Fuller S, Henry J, Rysdyk S, Cui J, Teklu AA, Verdin E, Benz C, Scheibye-Knudsen M. PMID: 39332852.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    38. Viral gene drive spread during herpes simplex virus 1 infection in mice. Nat Commun. 2024 09 17; 15(1):8161. Walter M, Haick AK, Riley R, Massa PA, Strongin DE, Klouser LM, Loprieno MA, Stensland L, Santo TK, Roychoudhury P, Aubert M, Taylor MP, Jerome KR, Verdin E. PMID: 39289368; PMCID: PMC11408514.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
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    148. Characterization of a new cucurbit-infecting ipomovirus from Sudan. Arch Virol. 2016 Oct; 161(10):2913-5. Desbiez C, Verdin E, Tepfer M, Wipf-Scheibel C, Millot P, Dafalla G, Lecoq H. PMID: 27430562.
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    149. Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity. Elife. 2016 05 31; 5. Shirakawa K, Wang L, Man N, Maksimoska J, Sorum AW, Lim HW, Lee IS, Shimazu T, Newman JC, Schröder S, Ott M, Marmorstein R, Meier J, Nimer S, Verdin E. PMID: 27244239; PMCID: PMC4931907.
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    150. LEDGIN-mediated Inhibition of Integrase-LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV. EBioMedicine. 2016 Jun; 8:248-264. Vranckx LS, Demeulemeester J, Saleh S, Boll A, Vansant G, Schrijvers R, Weydert C, Battivelli E, Verdin E, Cereseto A, Christ F, Gijsbers R, Debyser Z. PMID: 27428435; PMCID: PMC4919729.
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    151. A genetically novel, narrow-host-range isolate of cucumber mosaic virus (CMV) from rosemary. Arch Virol. 2016 Jul; 161(7):2013-7. Tepfer M, Girardot G, Fénéant L, Ben Tamarzizt H, Verdin E, Moury B, Jacquemond M. PMID: 27138549.
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    153. A Novel Sirtuin-3 Inhibitor, LC-0296, Inhibits Cell Survival and Proliferation, and Promotes Apoptosis of Head and Neck Cancer Cells. Anticancer Res. 2016 Jan; 36(1):49-60. Alhazzazi TY, Kamarajan P, Xu Y, Ai T, Chen L, Verdin E, Kapila YL. PMID: 26722027; PMCID: PMC5417072.
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    157. Correction: Repressive LTR Nucleosome Positioning by the BAF Complex Is Required for HIV Latency. PLoS Biol. 2015 Nov; 13(11):e1002302. Rafati H, Parra M, Hakre S, Moshkin Y, Verdin E, Mahmoudi T. PMID: 26569493; PMCID: PMC4646685.
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    158. Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits. Nat Med. 2015 Oct; 21(10):1154-62. Min SW, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, Minami SS, Defensor E, Mok SA, Sohn PD, Schilling B, Cong X, Ellerby L, Gibson BW, Johnson J, Krogan N, Shamloo M, Gestwicki J, Masliah E, Verdin E, Gan L. PMID: 26390242; PMCID: PMC4598295.
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    164. SIRT3 and SIRT5 regulate the enzyme activity and cardiolipin binding of very long-chain acyl-CoA dehydrogenase. PLoS One. 2015; 10(3):e0122297. Zhang Y, Bharathi SS, Rardin MJ, Uppala R, Verdin E, Gibson BW, Goetzman ES. PMID: 25811481; PMCID: PMC4374878.
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    167. Activation of SIRT3 by the NAD⁺ precursor nicotinamide riboside protects from noise-induced hearing loss. Cell Metab. 2014 Dec 02; 20(6):1059-68. Brown KD, Maqsood S, Huang JY, Pan Y, Harkcom W, Li W, Sauve A, Verdin E, Jaffrey SR. PMID: 25470550; PMCID: PMC4940130.
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    170. Adaptation of lettuce mosaic virus to Catharanthus roseus involves mutations in the central domain of the VPg. Mol Plant Microbe Interact. 2014 May; 27(5):491-7. Svanella-Dumas L, Verdin E, Faure C, German-Retana S, Gognalons P, Danet JL, Marais A, Candresse T. PMID: 24400938.
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    214. Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice. Aging (Albany NY). 2012 Jan; 4(1):13-27. Streeper RS, Grueter CA, Salomonis N, Cases S, Levin MC, Koliwad SK, Zhou P, Hirschey MD, Verdin E, Farese RV. PMID: 22291164; PMCID: PMC3292902.
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    215. Viruses of pepper crops in the Mediterranean basin: a remarkable stasis. Adv Virus Res. 2012; 84:127-62. Moury B, Verdin E. PMID: 22682167.
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    216. Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. PLoS Biol. 2011 Nov; 9(11):e1001206. Rafati H, Parra M, Hakre S, Moshkin Y, Verdin E, Mahmoudi T. PMID: 22140357; PMCID: PMC3226458.
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    217. SIRT3 regulates mitochondrial protein acetylation and intermediary metabolism. Cold Spring Harb Symp Quant Biol. 2011; 76:267-77. Hirschey MD, Shimazu T, Huang JY, Schwer B, Verdin E. PMID: 22114326.
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    218. Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes. J Biol Chem. 2012 Jan 06; 287(2):1090-9. Schröder S, Cho S, Zeng L, Zhang Q, Kaehlcke K, Mak L, Lau J, Bisgrove D, Schnölzer M, Verdin E, Zhou MM, Ott M. PMID: 22084242; PMCID: PMC3256921.
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    219. SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome. Mol Cell. 2011 Oct 21; 44(2):177-90. Hirschey MD, Shimazu T, Jing E, Grueter CA, Collins AM, Aouizerat B, Stancáková A, Goetzman E, Lam MM, Schwer B, Stevens RD, Muehlbauer MJ, Kakar S, Bass NM, Kuusisto J, Laakso M, Alt FW, Newgard CB, Farese RV, Kahn CR, Verdin E. PMID: 21856199; PMCID: PMC3563434.
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    220. The first identification of lysine malonylation substrates and its regulatory enzyme. Mol Cell Proteomics. 2011 Dec; 10(12):M111.012658. Peng C, Lu Z, Xie Z, Cheng Z, Chen Y, Tan M, Luo H, Zhang Y, He W, Yang K, Zwaans BM, Tishkoff D, Ho L, Lombard D, He TC, Dai J, Verdin E, Ye Y, Zhao Y. PMID: 21908771; PMCID: PMC3237090.
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    221. Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production. Proc Natl Acad Sci U S A. 2011 Aug 30; 108(35):14608-13. Jing E, Emanuelli B, Hirschey MD, Boucher J, Lee KY, Lombard D, Verdin EM, Kahn CR. PMID: 21873205; PMCID: PMC3167496.
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    222. SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2. Aging (Albany NY). 2011 Jun; 3(6):635-42. Hirschey MD, Shimazu T, Capra JA, Pollard KS, Verdin E. PMID: 21701047; PMCID: PMC3164371.
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    223. SIRT3 and cancer: tumor promoter or suppressor? Biochim Biophys Acta. 2011 Aug; 1816(1):80-8. Alhazzazi TY, Kamarajan P, Verdin E, Kapila YL. PMID: 21586315; PMCID: PMC3129516.
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    224. Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes. J Immunol. 2011 Apr 15; 186(8):4782-93. Kasler HG, Young BD, Mottet D, Lim HW, Collins AM, Olson EN, Verdin E. PMID: 21398603.
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    225. Epigenetic regulation of HIV latency. Curr Opin HIV AIDS. 2011 Jan; 6(1):19-24. Hakre S, Chavez L, Shirakawa K, Verdin E. PMID: 21242889.
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    226. Evolution and structure of Tomato spotted wilt virus populations: evidence of extensive reassortment and insights into emergence processes. J Gen Virol. 2011 Apr; 92(Pt 4):961-73. Tentchev D, Verdin E, Marchal C, Jacquet M, Aguilar JM, Moury B. PMID: 21169211.
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    227. SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. Cell Metab. 2010 Dec 01; 12(6):654-61. Shimazu T, Hirschey MD, Hua L, Dittenhafer-Reed KE, Schwer B, Lombard DB, Li Y, Bunkenborg J, Alt FW, Denu JM, Jacobson MP, Verdin E. PMID: 21109197; PMCID: PMC3310379.
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    228. Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab. 2010 Dec 01; 12(6):662-7. Qiu X, Brown K, Hirschey MD, Verdin E, Chen D. PMID: 21109198.
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    229. Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer. Cancer. 2011 Apr 15; 117(8):1670-8. Alhazzazi TY, Kamarajan P, Joo N, Huang JY, Verdin E, D'Silva NJ, Kapila YL. PMID: 21472714; PMCID: PMC3117020.
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    230. Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling. Trends Biochem Sci. 2010 Dec; 35(12):669-75. Verdin E, Hirschey MD, Finley LW, Haigis MC. PMID: 20863707; PMCID: PMC2992946.
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    231. Dietary restriction: standing up for sirtuins. Science. 2010 Aug 27; 329(5995):1012-3; author reply 1013-4. Baur JA, Chen D, Chini EN, Chua K, Cohen HY, de Cabo R, Deng C, Dimmeler S, Gius D, Guarente LP, Helfand SL, Imai S, Itoh H, Kadowaki T, Koya D, Leeuwenburgh C, McBurney M, Nabeshima Y, Neri C, Oberdoerffer P, Pestell RG, Rogina B, Sadoshima J, Sartorelli V, Serrano M, Sinclair DA, Steegborn C, Tatar M, Tissenbaum HA, Tong Q, Tsubota K, Vaquero A, Verdin E. PMID: 20798296; PMCID: PMC3985480.
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    232. Zmynd15 encodes a histone deacetylase-dependent transcriptional repressor essential for spermiogenesis and male fertility. J Biol Chem. 2010 Oct 08; 285(41):31418-26. Yan W, Si Y, Slaymaker S, Li J, Zheng H, Young DL, Aslanian A, Saunders L, Verdin E, Charo IF. PMID: 20675388; PMCID: PMC2951216.
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    233. HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals. Science. 2010 Jul 09; 329(5988):174-80. Trono D, Van Lint C, Rouzioux C, Verdin E, Barré-Sinoussi F, Chun TW, Chomont N. PMID: 20616270.
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    234. miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues. Aging (Albany NY). 2010 Jul; 2(7):415-31. Saunders LR, Sharma AD, Tawney J, Nakagawa M, Okita K, Yamanaka S, Willenbring H, Verdin E. PMID: 20634564; PMCID: PMC2933889.
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    235. In vivo, in vitro, and in silico analysis of methylation of the HIV-1 provirus. Methods. 2011 Jan; 53(1):47-53. Chávez L, Kauder S, Verdin E. PMID: 20670606; PMCID: PMC3566233.
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    236. HAT trick: p300, small molecule, inhibitor. Chem Biol. 2010 May 28; 17(5):417-8. Ott M, Verdin E. PMID: 20534339.
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    237. Acetate metabolism and aging: An emerging connection. Mech Ageing Dev. 2010 Jul-Aug; 131(7-8):511-6. Shimazu T, Hirschey MD, Huang JY, Ho LT, Verdin E. PMID: 20478325.
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    238. Regulatory signal transduction pathways for class IIa histone deacetylases. Curr Opin Pharmacol. 2010 Aug; 10(4):454-60. Parra M, Verdin E. PMID: 20447866.
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    239. Partial chromosome sequence of Spiroplasma citri reveals extensive viral invasion and important gene decay. Appl Environ Microbiol. 2010 Jun; 76(11):3420-6. Carle P, Saillard C, Carrère N, Carrère S, Duret S, Eveillard S, Gaurivaud P, Gourgues G, Gouzy J, Salar P, Verdin E, Breton M, Blanchard A, Laigret F, Bové JM, Renaudin J, Foissac X. PMID: 20363791; PMCID: PMC2876439.
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    240. Impact papers on aging in 2009. Aging (Albany NY). 2010 Mar; 2(3):111-21. Blagosklonny MV, Campisi J, Sinclair DA, Bartke A, Blasco MA, Bonner WM, Bohr VA, Brosh RM, Brunet A, Depinho RA, Donehower LA, Finch CE, Finkel T, Gorospe M, Gudkov AV, Hall MN, Hekimi S, Helfand SL, Karlseder J, Kenyon C, Kroemer G, Longo V, Nussenzweig A, Osiewacz HD, Peeper DS, Rando TA, Rudolph KL, Sassone-Corsi P, Serrano M, Sharpless NE, Skulachev VP, Tilly JL, Tower J, Verdin E, Vijg J. PMID: 20351400; PMCID: PMC2871240.
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    241. The Cellular lysine methyltransferase Set7/9-KMT7 binds HIV-1 TAR RNA, monomethylates the viral transactivator Tat, and enhances HIV transcription. Cell Host Microbe. 2010 Mar 18; 7(3):234-44. Pagans S, Kauder SE, Kaehlcke K, Sakane N, Schroeder S, Dormeyer W, Trievel RC, Verdin E, Schnolzer M, Ott M. PMID: 20227666; PMCID: PMC2844784.
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    242. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature. 2010 Mar 04; 464(7285):121-5. Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, Newgard CB, Farese RV, Alt FW, Kahn CR, Verdin E. PMID: 20203611; PMCID: PMC2841477.
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    243. Mitochondrial sirtuins. Biochim Biophys Acta. 2010 Aug; 1804(8):1645-51. Huang JY, Hirschey MD, Shimazu T, Ho L, Verdin E. PMID: 20060508.
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    244. First Report of Tomato torrado virus in Tomato Crops in France. Plant Dis. 2009 Dec; 93(12):1352. Verdin E, Gognalons P, Wipf-Scheibel C, Bornard I, Ridray G, Schoen L, Lecoq H. PMID: 30759535.
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    245. Histone deacetylase 7 and FoxA1 in estrogen-mediated repression of RPRM. Mol Cell Biol. 2010 Jan; 30(2):399-412. Malik S, Jiang S, Garee JP, Verdin E, Lee AV, O'Malley BW, Zhang M, Belaguli NS, Oesterreich S. PMID: 19917725; PMCID: PMC2798473.
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    246. CpG methylation controls reactivation of HIV from latency. PLoS Pathog. 2009 Aug; 5(8):e1000554. Blazkova J, Trejbalova K, Gondois-Rey F, Halfon P, Philibert P, Guiguen A, Verdin E, Olive D, Van Lint C, Hejnar J, Hirsch I. PMID: 19696893; PMCID: PMC2722084.
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    247. Epigenetic regulation of HIV-1 latency by cytosine methylation. PLoS Pathog. 2009 Jun; 5(6):e1000495. Kauder SE, Bosque A, Lindqvist A, Planelles V, Verdin E. PMID: 19557157; PMCID: PMC2695767.
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    248. A new splice variant of the mouse SIRT3 gene encodes the mitochondrial precursor protein. PLoS One. 2009; 4(3):e4986. Cooper HM, Huang JY, Verdin E, Spelbrink JN. PMID: 19333382; PMCID: PMC2659428.
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    249. Cell biology. Stress response and aging. Science. 2009 Feb 20; 323(5917):1021-2. Saunders LR, Verdin E. PMID: 19229027.
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    250. The serum response factor and a putative novel transcription factor regulate expression of the immediate-early gene Arc/Arg3.1 in neurons. J Neurosci. 2009 Feb 04; 29(5):1525-37. Pintchovski SA, Peebles CL, Kim HJ, Verdin E, Finkbeiner S. PMID: 19193899; PMCID: PMC2874324.
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    251. Pyridylalanine-containing hydroxamic acids as selective HDAC6 inhibitors. ChemMedChem. 2009 Feb; 4(2):283-90. Schäfer S, Saunders L, Schlimme S, Valkov V, Wagner JM, Kratz F, Sippl W, Verdin E, Jung M. PMID: 19090524.
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    252. Acetylation of mitochondrial proteins. Methods Enzymol. 2009; 457:137-47. Hirschey MD, Shimazu T, Huang JY, Verdin E. PMID: 19426866.
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    253. Thiobarbiturates as sirtuin inhibitors: virtual screening, free-energy calculations, and biological testing. ChemMedChem. 2008 Dec; 3(12):1965-76. Uciechowska U, Schemies J, Neugebauer RC, Huda EM, Schmitt ML, Meier R, Verdin E, Jung M, Sippl W. PMID: 18985648.
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    254. HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanism. Oncogene. 2009 Jan 15; 28(2):243-56. Mottet D, Pirotte S, Lamour V, Hagedorn M, Javerzat S, Bikfalvi A, Bellahcène A, Verdin E, Castronovo V. PMID: 18850004.
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    255. Destabilization of ERBB2 transcripts by targeting 3' untranslated region messenger RNA associated HuR and histone deacetylase-6. Mol Cancer Res. 2008 Jul; 6(7):1250-8. Scott GK, Marx C, Berger CE, Saunders LR, Verdin E, Schäfer S, Jung M, Benz CC. PMID: 18644987; PMCID: PMC2583372.
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    256. Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7. Proc Natl Acad Sci U S A. 2008 Jun 03; 105(22):7738-43. Wang S, Li X, Parra M, Verdin E, Bassel-Duby R, Olson EN. PMID: 18509061; PMCID: PMC2409381.
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    257. Structure-activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode. J Med Chem. 2008 Mar 13; 51(5):1203-13. Neugebauer RC, Uchiechowska U, Meier R, Hruby H, Valkov V, Verdin E, Sippl W, Jung M. PMID: 18269226.
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    258. Conserved metabolic regulatory functions of sirtuins. Cell Metab. 2008 Feb; 7(2):104-12. Schwer B, Verdin E. PMID: 18249170.
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    259. Regulation of human immunodeficiency virus-1 latency and its reactivation. Bull Mem Acad R Med Belg. 2008; 163(6):355-64; discussion 364-5. Verdin E. PMID: 19445107.
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    260. AROuSing SIRT1: identification of a novel endogenous SIRT1 activator. Mol Cell. 2007 Nov 09; 28(3):354-6. Verdin E. PMID: 17996699.
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    261. Phenylalanine-containing hydroxamic acids as selective inhibitors of class IIb histone deacetylases (HDACs). Bioorg Med Chem. 2008 Feb 15; 16(4):2011-33. Schäfer S, Saunders L, Eliseeva E, Velena A, Jung M, Schwienhorst A, Strasser A, Dickmanns A, Ficner R, Schlimme S, Sippl W, Verdin E, Jung M. PMID: 18054239.
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    262. Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation. Mol Cell Biol. 2007 Dec; 27(24):8807-14. Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, Guarente LP, Farese RV, Weissman S, Verdin E, Schwer B. PMID: 17923681; PMCID: PMC2169418.
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    263. Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis. PLoS One. 2007 Aug 29; 2(8):e784. North BJ, Verdin E. PMID: 17726514; PMCID: PMC1949146.
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    264. Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase. J Biol Chem. 2007 Nov 16; 282(46):33583-33592. Ahuja N, Schwer B, Carobbio S, Waltregny D, North BJ, Castronovo V, Maechler P, Verdin E. PMID: 17715127.
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    265. Sirtuins: critical regulators at the crossroads between cancer and aging. Oncogene. 2007 Aug 13; 26(37):5489-504. Saunders LR, Verdin E. PMID: 17694089.
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    266. Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription. Proc Natl Acad Sci U S A. 2007 Aug 21; 104(34):13690-5. Bisgrove DA, Mahmoudi T, Henklein P, Verdin E. PMID: 17690245; PMCID: PMC1959443.
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    267. Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases. Int J Cancer. 2007 Jul 15; 121(2):265-75. Barrett A, Santangelo S, Tan K, Catchpole S, Roberts K, Spencer-Dene B, Hall D, Scibetta A, Burchell J, Verdin E, Freemont P, Taylor-Papadimitriou J. PMID: 17373667.
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    268. Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation. J Biol Chem. 2007 Jul 06; 282(27):19546-55. North BJ, Verdin E. PMID: 17488717.
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    269. Histone deacetylase 7 functions as a key regulator of genes involved in both positive and negative selection of thymocytes. Mol Cell Biol. 2007 Jul; 27(14):5184-200. Kasler HG, Verdin E. PMID: 17470548; PMCID: PMC1951960.
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    270. A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP. J Biol Chem. 2007 May 18; 282(20):15248-57. Pagan JK, Arnold J, Hanchard KJ, Kumar R, Bruno T, Jones MJ, Richard DJ, Forrest A, Spurdle A, Verdin E, Crossley M, Fanciulli M, Chenevix-Trench G, Young DB, Khanna KK. PMID: 17379597.
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    271. Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes. Genes Dev. 2007 Mar 15; 21(6):638-43. Parra M, Mahmoudi T, Verdin E. PMID: 17369396; PMCID: PMC1820937.
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    272. First Report of the Presence of Tomato apical stunt viroid on Tomato in Sénégal. Plant Dis. 2007 Mar; 91(3):330. Candresse T, Marais A, Ollivier F, Verdin E, Blancard D. PMID: 30780593.
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    273. Design and evaluation of 'Linkerless' hydroxamic acids as selective HDAC8 inhibitors. Bioorg Med Chem Lett. 2007 May 15; 17(10):2874-8. Krennhrubec K, Marshall BL, Hedglin M, Verdin E, Ulrich SM. PMID: 17346959.
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    274. Knockdown of XAB2 enhances all-trans retinoic acid-induced cellular differentiation in all-trans retinoic acid-sensitive and -resistant cancer cells. Cancer Res. 2007 Feb 01; 67(3):1019-29. Ohnuma-Ishikawa K, Morio T, Yamada T, Sugawara Y, Ono M, Nagasawa M, Yasuda A, Morimoto C, Ohnuma K, Dang NH, Hosoi H, Verdin E, Mizutani S. PMID: 17283134.
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    275. Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition. J Med Chem. 2006 Dec 14; 49(25):7307-16. Trapp J, Jochum A, Meier R, Saunders L, Marshall B, Kunick C, Verdin E, Goekjian P, Sippl W, Jung M. PMID: 17149860.
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    276. Ornithine decarboxylase activity in tumor cell lines correlates with sensitivity to cell death induced by histone deacetylase inhibitors. Mol Cancer Ther. 2006 Nov; 5(11):2777-85. Saunders LR, Verdin E. PMID: 17121924.
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    277. Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2. Proc Natl Acad Sci U S A. 2006 Jul 05; 103(27):10224-10229. Schwer B, Bunkenborg J, Verdin RO, Andersen JS, Verdin E. PMID: 16788062; PMCID: PMC1502439.
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    278. The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter. J Biol Chem. 2006 Jul 21; 281(29):19960-8. Mahmoudi T, Parra M, Vries RG, Kauder SE, Verrijzer CP, Ott M, Verdin E. PMID: 16687403.
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    279. Detection and characterization of tobacco mild green mosaic virus (TMGMV) large type isolate from trailing petunia in France. Commun Agric Appl Biol Sci. 2006; 71(3 Pt B):1237-44. Parrella G, Verdin E, Gognalons P, Marchoux G. PMID: 17390885.
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    280. The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases. PLoS Genet. 2005 Dec; 1(6):e77. Olaharski AJ, Rine J, Marshall BL, Babiarz J, Zhang L, Verdin E, Smith MT. PMID: 16362078; PMCID: PMC1315280.
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    281. NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. EMBO J. 2006 Jan 11; 25(1):139-49. Williams SA, Chen LF, Kwon H, Ruiz-Jarabo CM, Verdin E, Greene WC. PMID: 16319923; PMCID: PMC1356344.
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    282. Molecular mechanisms of HIV-1 proviral latency. Expert Rev Anti Infect Ther. 2005 Oct; 3(5):805-14. Bisgrove D, Lewinski M, Bushman F, Verdin E. PMID: 16207172.
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    283. Preparation of enzymatically active recombinant class III protein deacetylases. Methods. 2005 Aug; 36(4):338-45. North BJ, Schwer B, Ahuja N, Marshall B, Verdin E. PMID: 16091304.
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    286. Tissue-resident macrophages are productively infected ex vivo by primary X4 isolates of human immunodeficiency virus type 1. J Virol. 2005 Apr; 79(8):5220-6. Jayakumar P, Berger I, Autschbach F, Weinstein M, Funke B, Verdin E, Goldsmith MA, Keppler OT. PMID: 15795306; PMCID: PMC1069582.
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    287. Histone deacetylase HDAC8 associates with smooth muscle alpha-actin and is essential for smooth muscle cell contractility. FASEB J. 2005 Jun; 19(8):966-8. Waltregny D, Glénisson W, Tran SL, North BJ, Verdin E, Colige A, Castronovo V. PMID: 15772115.
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    288. SIRT1 regulates HIV transcription via Tat deacetylation. PLoS Biol. 2005 Feb; 3(2):e41. Pagans S, Pedal A, North BJ, Kaehlcke K, Marshall BL, Dorr A, Hetzer-Egger C, Henklein P, Frye R, McBurney MW, Hruby H, Jung M, Verdin E, Ott M. PMID: 15719057; PMCID: PMC546329.
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    289. Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation. J Biol Chem. 2005 Apr 08; 280(14):13762-70. Parra M, Kasler H, McKinsey TA, Olson EN, Verdin E. PMID: 15623513.
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    290. Subtype selective substrates for histone deacetylases. J Med Chem. 2004 Oct 07; 47(21):5235-43. Heltweg B, Dequiedt F, Marshall BL, Brauch C, Yoshida M, Nishino N, Verdin E, Jung M. PMID: 15456267.
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    292. Prostratin antagonizes HIV latency by activating NF-kappaB. J Biol Chem. 2004 Oct 01; 279(40):42008-17. Williams SA, Chen LF, Kwon H, Fenard D, Bisgrove D, Verdin E, Greene WC. PMID: 15284245.
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    293. Screening of histone deacetylases (HDAC) expression in human prostate cancer reveals distinct class I HDAC profiles between epithelial and stromal cells. Eur J Histochem. 2004 Jul-Sep; 48(3):273-90. Waltregny D, North B, Van Mellaert F, de Leval J, Verdin E, Castronovo V. PMID: 15590418.
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    294. Sirtuins: Sir2-related NAD-dependent protein deacetylases. Genome Biol. 2004; 5(5):224. North BJ, Verdin E. PMID: 15128440; PMCID: PMC416462.
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    296. Measurement of mammalian histone deacetylase activity. Methods Enzymol. 2004; 377:180-96. Verdin E, Dequiedt F, Fischle W, Frye R, Marshall B, North B. PMID: 14979025.
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    297. Tat acetylation: a regulatory switch between early and late phases in HIV transcription elongation. Novartis Found Symp. 2004; 259:182-93; discussion 193-6, 223-5. Ott M, Dorr A, Hetzer-Egger C, Kaehlcke K, Schnolzer M, Henklein P, Cole P, Zhou MM, Verdin E. PMID: 15171254.
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    299. Acetylation of Tat defines a cyclinT1-independent step in HIV transactivation. Mol Cell. 2003 Jul; 12(1):167-76. Kaehlcke K, Dorr A, Hetzer-Egger C, Kiermer V, Henklein P, Schnoelzer M, Loret E, Cole PA, Verdin E, Ott M. PMID: 12887902.
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    300. "Candidatus Phlomobacter fragariae" Is the Prevalent Agent of Marginal Chlorosis of Strawberry in French Production Fields and Is Transmitted by the Planthopper Cixius wagneri (China). Phytopathology. 2003 Jun; 93(6):644-9. Danet JL, Foissac X, Zreik L, Salar P, Verdin E, Nourrisseau JG, Garnier M. PMID: 18943049.
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    301. 'Candidatus phytoplasma phoenicium' sp. nov., a novel phytoplasma associated with an emerging lethal disease of almond trees in Lebanon and Iran. Int J Syst Evol Microbiol. 2003 May; 53(Pt 3):833-838. Verdin E, Salar P, Danet JL, Choueiri E, Jreijiri F, El Zammar S, Gélie B, Bové JM, Garnier M. PMID: 12807209.
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    302. HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis. Immunity. 2003 May; 18(5):687-98. Dequiedt F, Kasler H, Fischle W, Kiermer V, Weinstein M, Herndier BG, Verdin E. PMID: 12753745.
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    304. HIV reproducibly establishes a latent infection after acute infection of T cells in vitro. EMBO J. 2003 Apr 15; 22(8):1868-77. Jordan A, Bisgrove D, Verdin E. PMID: 12682019; PMCID: PMC154479.
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    305. Transcriptional suppression of in vitro-integrated human immunodeficiency virus type 1 does not correlate with proviral DNA methylation. J Virol. 2003 Apr; 77(7):4025-32. Pion M, Jordan A, Biancotto A, Dequiedt F, Gondois-Rey F, Rondeau S, Vigne R, Hejnar J, Verdin E, Hirsch I. PMID: 12634362; PMCID: PMC150653.
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    306. The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. Mol Cell. 2003 Feb; 11(2):437-44. North BJ, Marshall BL, Borra MT, Denu JM, Verdin E. PMID: 12620231.
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    307. The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. J Cell Biol. 2002 Aug 19; 158(4):647-57. Schwer B, North BJ, Frye RA, Ott M, Verdin E. PMID: 12186850; PMCID: PMC2174009.
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    308. Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain. EMBO J. 2002 Jun 03; 21(11):2715-23. Dorr A, Kiermer V, Pedal A, Rackwitz HR, Henklein P, Schubert U, Zhou MM, Verdin E, Ott M. PMID: 12032084; PMCID: PMC125383.
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    309. First Report of Grapevine "Bois Noir" Disease and a New Phytoplasma Infecting Solanaceous Plants in Lebanon. Plant Dis. 2002 Jun; 86(6):697. Choueiri E, Jreijiri F, El Zammar S, Verdin E, Salar P, Danet JL, Bové J, Garnier M. PMID: 30823263.
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    330. Isoquinolinesulphonamide derivatives inhibit transcriptional elongation of human immunodeficiency virus type 1 RNA in a promyelocytic model of latency. Antivir Chem Chemother. 1999 Sep; 10(5):275-84. Critchfield JW, Ho O, Roberts BD, Van Lint C, Verdin E, Butera ST. PMID: 10574182.
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    361. The GAG precursor of simian immunodeficiency virus assembles into virus-like particles. EMBO J. 1989 Sep; 8(9):2653-60. Delchambre M, Gheysen D, Thines D, Thiriart C, Jacobs E, Verdin E, Horth M, Burny A, Bex F. PMID: 2684654; PMCID: PMC401271.
      View in: PubMed   Mentions: 101     Fields:    Translation:AnimalsCells
    362. Characterization of a common high-affinity receptor for reovirus serotypes 1 and 3 on endothelial cells. J Virol. 1989 Mar; 63(3):1318-25. Verdin EM, King GL, Maratos-Flier E. PMID: 2915382; PMCID: PMC247829.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    363. Uptake of reovirus serotype 1 by the lungs from the bloodstream is mediated by the viral hemagglutinin. J Virol. 1988 Feb; 62(2):545-51. Verdin EM, Lynn SP, Fields BN, Maratos-Flier E. PMID: 3336070; PMCID: PMC250566.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    364. Human immunodeficiency virus cell entry: new insights into the fusion mechanism. J Acquir Immune Defic Syndr (1988). 1988; 1(6):579-82. Burny A, Bex F, Brasseur R, Khim MC, Delchambre M, Horth M, Verdin E. PMID: 2852244.
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    365. Receptor-mediated vectorial transcytosis of epidermal growth factor by Madin-Darby canine kidney cells. J Cell Biol. 1987 Oct; 105(4):1595-601. Maratos-Flier E, Kao CY, Verdin EM, King GL. PMID: 3312235; PMCID: PMC2114648.
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    366. Visualization of viral clearance in the living animal. Science. 1987 Apr 24; 236(4800):439-42. Verdin EM, Maratos-Flier E, Kahn CR, Sodoyez JC, Sodoyez-Goffaux F, De Vos CJ, Lynn SP, Fields BN. PMID: 3031817.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    367. Persistent infection with a nontransforming RNA virus leads to impaired growth factor receptors and response. J Cell Physiol. 1986 Sep; 128(3):457-65. Verdin EM, Maratos-Flier E, Carpentier JL, Kahn CR. PMID: 3018005.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    368. Insulin oscillations per se do not affect glucose turnover parameters in normal man. J Clin Endocrinol Metab. 1986 Aug; 63(2):520-5. Paolisso G, Scheen AJ, Verdin EM, Luyckx AS, Lefebvre PJ. PMID: 3522623.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    369. Adipsic hypernatremia in a patient with pseudotumor cerebri and the primary empty sella syndrome. J Endocrinol Invest. 1985 Aug; 8(4):369-72. Verdin E, Smitz S, Thibaut A, Born J, Legros JJ, Luyckx A. PMID: 4067208.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    370. Similar metabolic effects of pulsatile versus continuous human insulin delivery during euglycemic, hyperinsulinemic glucose clamp in normal man. Diabetes. 1984 Dec; 33(12):1169-74. Verdin E, Castillo M, Luyckx AS, Lefebvre PJ. PMID: 6389233.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    371. VIP and the pancreatic cholera syndrome. N Engl J Med. 1984 May 31; 310(22):1465-6. Verdin EM, Green FW. PMID: 6325912.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    372. Circadian profiles of blood glucose and plasma free insulin during treatment with semisynthetic and biosynthetic human insulin, and comparison with conventional monocomponent preparations. Eur J Clin Pharmacol. 1983; 25(6):767-71. Castillo M, Nemery A, Verdin E, Lefebvre PJ, Luyckx AS. PMID: 6363099.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
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