"Pepstatins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
N-acylated oligopeptides isolated from culture filtrates of Actinomycetes, which act specifically to inhibit acid proteases such as pepsin and renin.
| Descriptor ID |
D010436
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| MeSH Number(s) |
D12.644.456.724
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Pepstatins".
Below are MeSH descriptors whose meaning is more specific than "Pepstatins".
This graph shows the total number of publications written about "Pepstatins" by people in this website by year, and whether "Pepstatins" was a major or minor topic of these publications.
Below are the most recent publications written about "Pepstatins" by people in Profiles.
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An Integrated Microfluidic Processor for DNA-Encoded Combinatorial Library Functional Screening. ACS Comb Sci. 2017 03 13; 19(3):181-192.
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Esterase mutation is a mechanism of resistance to antimalarial compounds. Nat Commun. 2017 01 20; 8:14240.
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Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease. Nature. 2016 Mar 03; 531(7592):105-9.
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Evolutionary Selection on Barrier Activity: Bar1 Is an Aspartyl Protease with Novel Substrate Specificity. mBio. 2015 Nov 24; 6(6):e01604-15.
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An allosteric modulator of HIV-1 protease shows equipotent inhibition of wild-type and drug-resistant proteases. J Med Chem. 2014 Aug 14; 57(15):6468-78.
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Inhibition of a secreted glutamic peptidase prevents growth of the fungus Talaromyces emersonii. J Biol Chem. 2008 Oct 24; 283(43):29186-95.
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Plasmodium food vacuole plasmepsins are activated by falcipains. J Biol Chem. 2008 May 09; 283(19):12870-6.
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ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation. Cell Death Differ. 2007 Feb; 14(2):230-9.
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Correction of the mineralization defect in hyp mice treated with protease inhibitors CA074 and pepstatin. Bone. 2006 Oct; 39(4):773-86.
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Antimalarial effects of human immunodeficiency virus type 1 protease inhibitors differ from those of the aspartic protease inhibitor pepstatin. Antimicrob Agents Chemother. 2006 Jun; 50(6):2207-9.