Our site may be slower due to heavy traffic from automated "bots" and AI crawlers. We're working to fix this.

Trypanosoma brucei rhodesiense

"Trypanosoma brucei rhodesiense" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
A hemoflagellate subspecies of parasitic protozoa that causes Rhodesian sleeping sickness in humans. It is carried by Glossina pallidipes, G. morsitans and occasionally other species of game-attacking tsetse flies.


expand / collapse Publications
This graph shows the total number of publications written about "Trypanosoma brucei rhodesiense" by people in this website by year, and whether "Trypanosoma brucei rhodesiense" was a major or minor topic of these publications.
Below are the most recent publications written about "Trypanosoma brucei rhodesiense" by people in Profiles.
  1. Carmaphycin B-Based Proteasome Inhibitors to Treat Human African Trypanosomiasis: Structure-Activity Relationship and In Vivo Efficacy. ACS Infect Dis. 2024 Dec 13; 10(12):4182-4193.
    View in: PubMed
  2. Development of Novel Peptidyl Nitriles Targeting Rhodesain and Falcipain-2 for the Treatment of Sleeping Sickness and Malaria. Int J Mol Sci. 2024 Apr 17; 25(8).
    View in: PubMed
  3. Should the enzyme name 'rhodesain' be discontinued? Mol Biochem Parasitol. 2021 09; 245:111395.
    View in: PubMed
  4. Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents. Eur J Med Chem. 2018 Aug 05; 156:53-60.
    View in: PubMed
  5. Substituted 2-phenylimidazopyridines: a new class of drug leads for human African trypanosomiasis. J Med Chem. 2014 Feb 13; 57(3):828-35.
    View in: PubMed
  6. Crystal structures of a bioactive 6'-hydroxy variant of sisomicin bound to the bacterial and protozoal ribosomal decoding sites. ChemMedChem. 2013 May; 8(5):733-9.
    View in: PubMed
  7. Synthesis, biological evaluation, and structure-activity relationships of N-benzoyl-2-hydroxybenzamides as agents active against P. falciparum (K1 strain), Trypanosomes, and Leishmania. J Med Chem. 2012 Apr 12; 55(7):3088-100.
    View in: PubMed
  8. The Trypanosoma brucei flagellum: moving parasites in new directions. Annu Rev Microbiol. 2009; 63:335-62.
    View in: PubMed
  9. Signal transduction, gene transcription, and cytokine production triggered in macrophages by exposure to trypanosome DNA. Infect Immun. 2006 Aug; 74(8):4530-7.
    View in: PubMed
  10. Application of multicomponent reactions to antimalarial drug discovery. Part 2: New antiplasmodial and antitrypanosomal 4-aminoquinoline gamma- and delta-lactams via a 'catch and release' protocol. Bioorg Med Chem. 2006 Aug 15; 14(16):5605-15.
    View in: PubMed