Qili Liu, PhD
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Title(s) | Assistant Professor, Anatomy |
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School | School of Medicine |
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Address | 1550 Fourth St San Francisco CA 94158
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Phone | -- |
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vCard | Download vCard |
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Biography | 2020 | | Klingenstein-Simons Fellowship Award in Neuroscience | | 2019 | | UCSF Weill Pilot Award for Junior Investigators | | 2019 | | UCSF PBBR New Frontiers Research Award | | 2019 | | Mallinckrodt Young Investigator Award | | 2019 | | UCSF NORC Pilot and Feasibility Award |
Overview Animals can exhibit hunger for not only calories but also specific nutrients, which energize behaviors to search for and ingest particular types of food in response to internal nutritional deficiency. My lab aims to understand the neurobiological basis of nutrient-specific appetite, and investigate how hunger for distinct nutrients are systematically coordinated to ensure that a balanced diet is consumed. To this end, we will harness the power of the Drosophila model system and employ a multidisciplinary approach, including large-scale genetic and behavioral analyses, immunohistochemistry, functional imaging, and patch-clamp electrophysiology. These studies will shed light on the fundamental principles for the organization and modulation of motivated behaviors. Given the global obesity epidemic, illuminating the regulation of food choice guided by nutrient specific appetite may facilitate the development of novel treatments for obesity.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
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Clock-Generated Temporal Codes Determine Synaptic Plasticity to Control Sleep. Cell. 2018 11 15; 175(5):1213-1227.e18.
Tabuchi M, Monaco JD, Duan G, Bell B, Liu S, Liu Q, Zhang K, Wu MN. PMID: 30318147.
View in: PubMed Mentions: 4 Fields: Translation: AnimalsCells
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A Genetic Toolkit for Dissecting Dopamine Circuit Function in Drosophila. Cell Rep. 2018 Apr 10; 23(2):652-665.
Xie T, Ho MCW, Liu Q, Horiuchi W, Lin CC, Task D, Luan H, White BH, Potter CJ, Wu MN. PMID: 29642019.
View in: PubMed Mentions: 13 Fields: Translation: AnimalsCells
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Branch-specific plasticity of a bifunctional dopamine circuit encodes protein hunger. Science. 2017 05 05; 356(6337):534-539.
Liu Q, Tabuchi M, Liu S, Kodama L, Horiuchi W, Daniels J, Chiu L, Baldoni D, Wu MN. PMID: 28473588.
View in: PubMed Mentions: 21 Fields: Translation: AnimalsCells
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Sleep Drive Is Encoded by Neural Plastic Changes in a Dedicated Circuit. Cell. 2016 Jun 02; 165(6):1347-1360.
Liu S, Liu Q, Tabuchi M, Wu MN. PMID: 27212237.
View in: PubMed Mentions: 57 Fields: Translation: AnimalsCells
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Sleep interacts with aß to modulate intrinsic neuronal excitability. Curr Biol. 2015 Mar 16; 25(6):702-712.
Tabuchi M, Lone SR, Liu S, Liu Q, Zhang J, Spira AP, Wu MN. PMID: 25754641.
View in: PubMed Mentions: 45 Fields: Translation: HumansAnimalsCells
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WIDE AWAKE mediates the circadian timing of sleep onset. Neuron. 2014 Apr 02; 82(1):151-66.
Liu S, Lamaze A, Liu Q, Tabuchi M, Yang Y, Fowler M, Bharadwaj R, Zhang J, Bedont J, Blackshaw S, Lloyd TE, Montell C, Sehgal A, Koh K, Wu MN. PMID: 24631345.
View in: PubMed Mentions: 32 Fields: Translation: AnimalsCells
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Two dopaminergic neurons signal to the dorsal fan-shaped body to promote wakefulness in Drosophila. Curr Biol. 2012 Nov 20; 22(22):2114-23.
Liu Q, Liu S, Kodama L, Driscoll MR, Wu MN. PMID: 23022067.
View in: PubMed Mentions: 97 Fields: Translation: AnimalsCells
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The ARGONAUTE10 gene modulates shoot apical meristem maintenance and establishment of leaf polarity by repressing miR165/166 in Arabidopsis. Plant J. 2009 Apr; 58(1):27-40.
Liu Q, Yao X, Pi L, Wang H, Cui X, Huang H. PMID: 19054365.
View in: PubMed Mentions: 51 Fields: Translation: Animals
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Genetic interaction between the AS1-AS2 and RDR6-SGS3-AGO7 pathways for leaf morphogenesis. Plant Cell Physiol. 2006 Jul; 47(7):853-63.
Xu L, Yang L, Pi L, Liu Q, Ling Q, Wang H, Poethig RS, Huang H. PMID: 16699177.
View in: PubMed Mentions: 28 Fields: Translation: AnimalsCells
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Year | Publications |
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2006 | 1 | 2008 | 1 | 2012 | 1 | 2014 | 1 | 2015 | 1 | 2016 | 1 | 2017 | 1 | 2018 | 2 |
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