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Shawn Douglas, PhD

TitleAssistant Professor
InstitutionUniversity of California San Francisco
DepartmentCellular Molecular Pharmacology
Address600 16th St
San Francisco CA 94158
Phone415-502-1947
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    Collapse Research 
    Collapse Research Activities and Funding
    DNA Nanostructures for High-Throughput Cryo-EM Studies of Small Macromolecules
    NIH/NIGMS R35GM125027Mar 1, 2018 - Feb 28, 2023
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Douglas S. Bringing proteins into the fold. Science. 2017 03 24; 355(6331):1261-1262. PMID: 28336623.
      View in: PubMed
    2. Niekamp S, Blumer K, Nafisi PM, Tsui K, Garbutt J, Douglas S. Folding complex DNA nanostructures from limited sets of reusable sequences. Nucleic Acids Res. 2016 06 20; 44(11):e102. PMID: 27036861; PMCID: PMC4914096.
    3. Ball MP, Thakuria JV, Zaranek AW, Clegg T, Rosenbaum AM, Wu X, Angrist M, Bhak J, Bobe J, Callow MJ, Cano C, Chou MF, Chung WK, Douglas S, Estep PW, Gore A, Hulick P, Labarga A, Lee JH, Lunshof JE, Kim BC, Kim JI, Li Z, Murray MF, Nilsen GB, Peters BA, Raman AM, Rienhoff HY, Robasky K, Wheeler MT, Vandewege W, Vorhaus DB, Yang JL, Yang L, Aach J, Ashley EA, Drmanac R, Kim SJ, Li JB, Peshkin L, Seidman CE, Seo JS, Zhang K, Rehm HL, Church GM. A public resource facilitating clinical use of genomes. Proc Natl Acad Sci U S A. 2012 Jul 24; 109(30):11920-7. PMID: 22797899; PMCID: PMC3409785.
    4. Douglas S, Bachelet I, Church GM. A logic-gated nanorobot for targeted transport of molecular payloads. Science. 2012 Feb 17; 335(6070):831-4. PMID: 22344439.
      View in: PubMed
    5. Ke Y, Douglas S, Liu M, Sharma J, Cheng A, Leung A, Liu Y, Shih WM, Yan H. Multilayer DNA origami packed on a square lattice. J Am Chem Soc. 2009 Nov 04; 131(43):15903-8. PMID: 19807088; PMCID: PMC2821935.
    6. Dietz H, Douglas S, Shih WM. Folding DNA into twisted and curved nanoscale shapes. Science. 2009 Aug 07; 325(5941):725-30. PMID: 19661424; PMCID: PMC2737683.
    7. Douglas S, Marblestone AH, Teerapittayanon S, Vazquez A, Church GM, Shih WM. Rapid prototyping of 3D DNA-origami shapes with caDNAno. Nucleic Acids Res. 2009 Aug; 37(15):5001-6. PMID: 19531737; PMCID: PMC2731887.
    8. Douglas S, Dietz H, Liedl T, Högberg B, Graf F, Shih WM. Self-assembly of DNA into nanoscale three-dimensional shapes. Nature. 2009 May 21; 459(7245):414-8. PMID: 19458720; PMCID: PMC2688462.
    9. Gerstein M, Douglas S. RNAi development. PLoS Comput Biol. 2007 Apr 27; 3(4):e80. PMID: 17465677; PMCID: PMC1857818.
    10. Douglas S, Chou JJ, Shih WM. DNA-nanotube-induced alignment of membrane proteins for NMR structure determination. Proc Natl Acad Sci U S A. 2007 Apr 17; 104(16):6644-8. PMID: 17404217; PMCID: PMC1871839.
    11. Smith A, Greenbaum D, Douglas S, Long M, Gerstein M. Network security and data integrity in academia: an assessment and a proposal for large-scale archiving. Genome Biol. 2005; 6(9):119. PMID: 16168090; PMCID: PMC1242199.
    12. Douglas S, Montelione GT, Gerstein M. PubNet: a flexible system for visualizing literature derived networks. Genome Biol. 2005; 6(9):R80. PMID: 16168087; PMCID: PMC1242215.
    13. Acton TB, Gunsalus KC, Xiao R, Ma LC, Aramini J, Baran MC, Chiang YW, Climent T, Cooper B, Denissova NG, Douglas S, Everett JK, Ho CK, Macapagal D, Rajan PK, Shastry R, Shih LY, Swapna GV, Wilson M, Wu M, Gerstein M, Inouye M, Hunt JF, Montelione GT. Robotic cloning and Protein Production Platform of the Northeast Structural Genomics Consortium. Methods Enzymol. 2005; 394:210-43. PMID: 15808222.
      View in: PubMed
    14. Greenbaum D, Douglas S, Smith A, Lim J, Fischer M, Schultz M, Gerstein M. Computer security in academia-a potential roadblock to distributed annotation of the human genome. Nat Biotechnol. 2004 Jun; 22(6):771-2. PMID: 15175700.
      View in: PubMed
    15. Goh CS, Lan N, Douglas S, Wu B, Echols N, Smith A, Milburn D, Montelione GT, Zhao H, Gerstein M. Mining the structural genomics pipeline: identification of protein properties that affect high-throughput experimental analysis. J Mol Biol. 2004 Feb 06; 336(1):115-30. PMID: 14741208.
      View in: PubMed
    16. Goh CS, Lan N, Echols N, Douglas S, Milburn D, Bertone P, Xiao R, Ma LC, Zheng D, Wunderlich Z, Acton T, Montelione GT, Gerstein M. SPINE 2: a system for collaborative structural proteomics within a federated database framework. Nucleic Acids Res. 2003 Jun 01; 31(11):2833-8. PMID: 12771210; PMCID: PMC156730.
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