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Shawn Douglas, PhD

Title(s)Assistant Professor, Cellular Molecular Pharmacology
SchoolSchool of Medicine
Phone415-502-1947
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    Collapse Research 
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    DNA Nanostructures for High-Throughput Cryo-EM Studies of Small Macromolecules
    NIH/NIGMS R35GM125027Mar 1, 2018 - Feb 28, 2023
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Nafisi PM, Aksel T, Douglas SM. Construction of a novel phagemid to produce custom DNA origami scaffolds. Synth Biol (Oxf). 2018 Jan; 3(1). PMID: 30984875.
      View in: PubMed
    2. Douglas SM. Bringing proteins into the fold. Science. 2017 03 24; 355(6331):1261-1262. PMID: 28336623.
      View in: PubMed
    3. Niekamp S, Blumer K, Nafisi PM, Tsui K, Garbutt J, Douglas SM. Folding complex DNA nanostructures from limited sets of reusable sequences. Nucleic Acids Res. 2016 06 20; 44(11):e102. PMID: 27036861.
      View in: PubMed
    4. Ball MP, Thakuria JV, Zaranek AW, Clegg T, Rosenbaum AM, Wu X, Angrist M, Bhak J, Bobe J, Callow MJ, Cano C, Chou MF, Chung WK, Douglas SM, Estep PW, Gore A, Hulick P, Labarga A, Lee JH, Lunshof JE, Kim BC, Kim JI, Li Z, Murray MF, Nilsen GB, Peters BA, Raman AM, Rienhoff HY, Robasky K, Wheeler MT, Vandewege W, Vorhaus DB, Yang JL, Yang L, Aach J, Ashley EA, Drmanac R, Kim SJ, Li JB, Peshkin L, Seidman CE, Seo JS, Zhang K, Rehm HL, Church GM. A public resource facilitating clinical use of genomes. Proc Natl Acad Sci U S A. 2012 Jul 24; 109(30):11920-7. PMID: 22797899.
      View in: PubMed
    5. Douglas SM, Bachelet I, Church GM. A logic-gated nanorobot for targeted transport of molecular payloads. Science. 2012 Feb 17; 335(6070):831-4. PMID: 22344439.
      View in: PubMed
    6. Ke Y, Douglas SM, Liu M, Sharma J, Cheng A, Leung A, Liu Y, Shih WM, Yan H. Multilayer DNA origami packed on a square lattice. J Am Chem Soc. 2009 Nov 04; 131(43):15903-8. PMID: 19807088.
      View in: PubMed
    7. Dietz H, Douglas SM, Shih WM. Folding DNA into twisted and curved nanoscale shapes. Science. 2009 Aug 07; 325(5941):725-30. PMID: 19661424.
      View in: PubMed
    8. Douglas SM, Marblestone AH, Teerapittayanon S, Vazquez A, Church GM, Shih WM. Rapid prototyping of 3D DNA-origami shapes with caDNAno. Nucleic Acids Res. 2009 Aug; 37(15):5001-6. PMID: 19531737.
      View in: PubMed
    9. Douglas SM, Dietz H, Liedl T, Högberg B, Graf F, Shih WM. Self-assembly of DNA into nanoscale three-dimensional shapes. Nature. 2009 May 21; 459(7245):414-8. PMID: 19458720.
      View in: PubMed
    10. Gerstein M, Douglas SM. RNAi development. PLoS Comput Biol. 2007 Apr 27; 3(4):e80. PMID: 17465677.
      View in: PubMed
    11. Douglas SM, Chou JJ, Shih WM. DNA-nanotube-induced alignment of membrane proteins for NMR structure determination. Proc Natl Acad Sci U S A. 2007 Apr 17; 104(16):6644-8. PMID: 17404217.
      View in: PubMed
    12. Smith A, Greenbaum D, Douglas SM, Long M, Gerstein M. Network security and data integrity in academia: an assessment and a proposal for large-scale archiving. Genome Biol. 2005; 6(9):119. PMID: 16168090; PMCID: PMC1242199.
    13. Douglas SM, Montelione GT, Gerstein M. PubNet: a flexible system for visualizing literature derived networks. Genome Biol. 2005; 6(9):R80. PMID: 16168087; PMCID: PMC1242215.
    14. Acton TB, Gunsalus KC, Xiao R, Ma LC, Aramini J, Baran MC, Chiang YW, Climent T, Cooper B, Denissova NG, Douglas SM, Everett JK, Ho CK, Macapagal D, Rajan PK, Shastry R, Shih LY, Swapna GV, Wilson M, Wu M, Gerstein M, Inouye M, Hunt JF, Montelione GT. Robotic cloning and Protein Production Platform of the Northeast Structural Genomics Consortium. Methods Enzymol. 2005; 394:210-43. PMID: 15808222.
      View in: PubMed
    15. Greenbaum D, Douglas SM, Smith A, Lim J, Fischer M, Schultz M, Gerstein M. Computer security in academia-a potential roadblock to distributed annotation of the human genome. Nat Biotechnol. 2004 Jun; 22(6):771-2. PMID: 15175700.
      View in: PubMed
    16. Goh CS, Lan N, Douglas SM, Wu B, Echols N, Smith A, Milburn D, Montelione GT, Zhao H, Gerstein M. Mining the structural genomics pipeline: identification of protein properties that affect high-throughput experimental analysis. J Mol Biol. 2004 Feb 06; 336(1):115-30. PMID: 14741208.
      View in: PubMed
    17. Goh CS, Lan N, Echols N, Douglas SM, Milburn D, Bertone P, Xiao R, Ma LC, Zheng D, Wunderlich Z, Acton T, Montelione GT, Gerstein M. SPINE 2: a system for collaborative structural proteomics within a federated database framework. Nucleic Acids Res. 2003 Jun 01; 31(11):2833-8. PMID: 12771210; PMCID: PMC156730.