Ron Vale, PhD

Title(s)Professor Emeritus, Cellular Molecular Pharmacology
SchoolSchool of Medicine
AddressLocation Required, #N312E
Varies CA 00000
Phone415-502-6305
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    Other Positions
    Title(s)Howard Hughes Investigator


    Collapse Biography 
    Collapse Awards and Honors
    2019Canada Gairdner International Award
    2014Institute of Medicine Member
    2012Albert Lasker Basic Medical Research Award

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Regulation of Microtubule-Based Motility
    NIH R35GM118106Jul 1, 2016 - Jun 30, 2021
    Role: Principal Investigator
    Creating an online resource center for training and professional development in the biomedical sciences
    NIH R25GM116704Sep 25, 2015 - Jul 31, 2020
    Role: Principal Investigator
    Structure and mechanism of the dynein motor
    NIH R01GM097312Apr 1, 2011 - Mar 31, 2019
    Role: Principal Investigator
    Open Source Microscopy Software
    NIH R01EB007187Apr 1, 2007 - Aug 31, 2015
    Role: Principal Investigator
    Interdisciplinary Training in Quantitative Cell Biology
    NIH R13GM085967Sep 20, 2004 - May 31, 2018
    Role: Principal Investigator
    Interdisciplinary Training in Quantitative Cell Biology
    NIH R13DK069546Sep 20, 2004 - Jul 31, 2007
    Role: Principal Investigator
    Cell Migration Consortium
    NIH U54GM064346Sep 15, 2001 - Jul 31, 2014
    Role: Co-Investigator
    Structure and Function of Molecular Motors
    NIH P01AR042895Jul 6, 1994 - Jun 30, 2010
    Role: Co-Investigator
    PROTEIN MODULATORS OF MICROTUBULE DYNAMICS
    NIH R01GM049752Aug 1, 1993 - Jul 31, 1998
    Role: Principal Investigator
    Microtubule Complexes Involved in Intracelluar Transport
    NIH R37GM038499Feb 1, 1988 - Aug 31, 2016
    Role: Principal Investigator
    Macromoleclar Complexes Involved in Cellular Transport
    NIH R01GM038499Feb 1, 1988 - Aug 31, 2006
    Role: Principal Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking. Cell. 2023 Oct 19. Chen Z, Shiozaki M, Haas KM, Skinner WM, Zhao S, Guo C, Polacco BJ, Yu Z, Krogan NJ, Lishko PV, Kaake RM, Vale RD, Agard DA. PMID: 37865089.
      View in: PubMed   Mentions: 1     Fields:    
    2. Nucleolar dynamics are determined by the ordered assembly of the ribosome. bioRxiv. 2023 Sep 27. Sheu-Gruttadauria J, Yan X, Stuurman N, Floor SN, Vale RD. PMID: 37808656; PMCID: PMC10557630.
      View in: PubMed   Mentions:
    3. CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis. Immunity. 2023 Sep 12; 56(9):2172. Morrissey MA, Kern N, Vale RD. PMID: 37703830; PMCID: PMC10593492.
      View in: PubMed   Mentions: 1     Fields:    
    4. Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs. Proc Natl Acad Sci U S A. 2023 01 17; 120(3):e2215071120. Das MR, Chang Y, Anderson R, Saunders RA, Zhang N, Tomberlin CP, Vale RD, Jain A. PMID: 36623192; PMCID: PMC9934169.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    5. In situ cryo-electron tomography reveals the asymmetric architecture of mammalian sperm axonemes. Nat Struct Mol Biol. 2023 03; 30(3):360-369. Chen Z, Greenan GA, Shiozaki M, Liu Y, Skinner WM, Zhao X, Zhao S, Yan R, Yu Z, Lishko PV, Agard DA, Vale RD. PMID: 36593309; PMCID: PMC10023559.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    6. DNA origami patterning of synthetic T cell receptors reveals spatial control of the sensitivity and kinetics of signal activation. Proc Natl Acad Sci U S A. 2021 10 05; 118(40). Dong R, Aksel T, Chan W, Germain RN, Vale RD, Douglas SM. PMID: 34588308; PMCID: PMC8501782.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    7. Direct detection of SARS-CoV-2 RNA using high-contrast pH-sensitive dyes. J Biomol Tech. 2021 09; 32(3):121-133. Brown TA, Schaefer KS, Tsang A, Yi HA, Grimm JB, Lemire AL, Jradi FM, Kim C, McGowan K, Ritola K, Armstrong DT, Mostafa HH, Korff W, Vale RD, Lavis LD. PMID: 35027870; PMCID: PMC8730524.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    8. Three-color single-molecule imaging reveals conformational dynamics of dynein undergoing motility. Proc Natl Acad Sci U S A. 2021 08 03; 118(31). Niekamp S, Stuurman N, Zhang N, Vale RD. PMID: 34326255; PMCID: PMC8346880.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    9. Tight nanoscale clustering of Fcγ receptors using DNA origami promotes phagocytosis. Elife. 2021 06 03; 10. Kern N, Dong R, Douglas SM, Vale RD, Morrissey MA. PMID: 34080973; PMCID: PMC8175083.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    10. High-content imaging-based pooled CRISPR screens in mammalian cells. J Cell Biol. 2021 02 01; 220(2). Yan X, Stuurman N, Ribeiro SA, Tanenbaum ME, Horlbeck MA, Liem CR, Jost M, Weissman JS, Vale RD. PMID: 33465779; PMCID: PMC7821101.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    11. Structure of the radial spoke head and insights into its role in mechanoregulation of ciliary beating. Nat Struct Mol Biol. 2021 01; 28(1):20-28. Grossman-Haham I, Coudray N, Yu Z, Wang F, Zhang N, Bhabha G, Vale RD. PMID: 33318704; PMCID: PMC7855469.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    12. Coupled membrane lipid miscibility and phosphotyrosine-driven protein condensation phase transitions. Biophys J. 2021 04 06; 120(7):1257-1265. Chung JK, Huang WYC, Carbone CB, Nocka LM, Parikh AN, Vale RD, Groves JT. PMID: 33080222; PMCID: PMC8059084.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    13. Cell Sorting in Hydra vulgaris Arises from Differing Capacities for Epithelialization between Cell Types. Curr Biol. 2020 10 05; 30(19):3713-3723.e3. Skokan TD, Vale RD, McKinley KL. PMID: 32795440; PMCID: PMC7541579.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    14. CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis. Immunity. 2020 08 18; 53(2):290-302.e6. Morrissey MA, Kern N, Vale RD. PMID: 32768386; PMCID: PMC7453839.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    15. Rewired signaling network in T cells expressing the chimeric antigen receptor (CAR). EMBO J. 2020 08 17; 39(16):e104730. Dong R, Libby KA, Blaeschke F, Fuchs W, Marson A, Vale RD, Su X. PMID: 32643825; PMCID: PMC7429742.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    16. Tuning the Antigen Density Requirement for CAR T-cell Activity. Cancer Discov. 2020 05; 10(5):702-723. Majzner RG, Rietberg SP, Sotillo E, Dong R, Vachharajani VT, Labanieh L, Myklebust JH, Kadapakkam M, Weber EW, Tousley AM, Richards RM, Heitzeneder S, Nguyen SM, Wiebking V, Theruvath J, Lynn RC, Xu P, Dunn AR, Vale RD, Mackall CL. PMID: 32193224; PMCID: PMC7939454.
      View in: PubMed   Mentions: 159     Fields:    Translation:HumansAnimalsCells
    17. A 6-nm ultra-photostable DNA FluoroCube for fluorescence imaging. Nat Methods. 2020 04; 17(4):437-441. Niekamp S, Stuurman N, Vale RD. PMID: 32203385; PMCID: PMC7138518.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    18. Electron cryotomography of intact motile cilia defines the basal body to axoneme transition. J Cell Biol. 2020 01 06; 219(1). Greenan GA, Vale RD, Agard DA. PMID: 31874113; PMCID: PMC7039205.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    19. A composition-dependent molecular clutch between T cell signaling condensates and actin. Elife. 2019 07 03; 8. Ditlev JA, Vega AR, Köster DV, Su X, Tani T, Lakoduk AM, Vale RD, Mayor S, Jaqaman K, Rosen MK. PMID: 31268421; PMCID: PMC6624021.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    20. Coupling of ATPase activity, microtubule binding, and mechanics in the dynein motor domain. EMBO J. 2019 07 01; 38(13):e101414. Niekamp S, Coudray N, Zhang N, Vale RD, Bhabha G. PMID: 31268607; PMCID: PMC6600642.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    21. Keep Your Eyes on the Prize. Cell. 2019 04 18; 177(3):506-509. Vale RD. PMID: 30952445.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    22. CRACR2a is a calcium-activated dynein adaptor protein that regulates endocytic traffic. J Cell Biol. 2019 05 06; 218(5):1619-1633. Wang Y, Huynh W, Skokan TD, Lu W, Weiss A, Vale RD. PMID: 30814157; PMCID: PMC6504896.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    23. Nanometer-accuracy distance measurements between fluorophores at the single-molecule level. Proc Natl Acad Sci U S A. 2019 03 05; 116(10):4275-4284. Niekamp S, Sung J, Huynh W, Bhabha G, Vale RD, Stuurman N. PMID: 30770448; PMCID: PMC6410877.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    24. Spatial control of Draper receptor signaling initiates apoptotic cell engulfment. J Cell Biol. 2018 11 05; 217(11):3977-3992. Williamson AP, Vale RD. PMID: 30139739; PMCID: PMC6219719.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    25. Insights into centriole geometry revealed by cryotomography of doublet and triplet centrioles. Elife. 2018 08 06; 7. Greenan GA, Keszthelyi B, Vale RD, Agard DA. PMID: 30080137; PMCID: PMC6110610.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    26. Publish peer reviews. Nature. 2018 08; 560(7720):545-547. Polka JK, Kiley R, Konforti B, Stern B, Vale RD. PMID: 30158621.
      View in: PubMed   Mentions: 24     Fields:    
    27. Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding. Cell. 2018 07 26; 174(3):672-687.e27. Sibener LV, Fernandes RA, Kolawole EM, Carbone CB, Liu F, McAffee D, Birnbaum ME, Yang X, Su LF, Yu W, Dong S, Gee MH, Jude KM, Davis MM, Groves JT, Goddard WA, Heath JR, Evavold BD, Vale RD, Garcia KC. PMID: 30053426; PMCID: PMC6140336.
      View in: PubMed   Mentions: 131     Fields:    Translation:HumansCells
    28. Publisher Correction: The cytoplasmic dynein transport machinery and its many cargoes. Nat Rev Mol Cell Biol. 2018 Jul; 19(7):479. Reck-Peterson SL, Redwine WB, Vale RD, Carter AP. PMID: 29740130.
      View in: PubMed   Mentions: 5     Fields:    
    29. Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia. Elife. 2018 06 13; 7. McKinley KL, Stuurman N, Royer LA, Schartner C, Castillo-Azofeifa D, Delling M, Klein OD, Vale RD. PMID: 29897330; PMCID: PMC6023609.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    30. Chimeric antigen receptors that trigger phagocytosis. Elife. 2018 06 04; 7. Morrissey MA, Williamson AP, Steinbach AM, Roberts EW, Kern N, Headley MB, Vale RD. PMID: 29862966; PMCID: PMC6008046.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansAnimalsCells
    31. The cytoplasmic dynein transport machinery and its many cargoes. Nat Rev Mol Cell Biol. 2018 06; 19(6):382-398. Reck-Peterson SL, Redwine WB, Vale RD, Carter AP. PMID: 29662141; PMCID: PMC6457270.
      View in: PubMed   Mentions: 251     Fields:    Translation:HumansAnimalsCells
    32. In vitro reconstitution of T cell receptor-mediated segregation of the CD45 phosphatase. Proc Natl Acad Sci U S A. 2017 10 31; 114(44):E9338-E9345. Carbone CB, Kern N, Fernandes RA, Hui E, Su X, Garcia KC, Vale RD. PMID: 29042512; PMCID: PMC5676914.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    33. Not just Salk. Science. 2017 09 15; 357(6356):1105-1106. Greider C, Hopkins N, Steitz J, Amon A, Asai D, Barres B, Bass B, Bassler B, Birgeneau R, Bjorkman P, Botchan M, Brugge J, Cech T, Colwell R, Craig N, deLange T, Eisen M, Gottesman S, Green R, Handelsman J, Kimble J, King MC, Lehmann R, Marder E, Mullins D, O'Shea E, Schmid S, Seydoux G, Spradling A, Storz G, Szostak J, Telesnitsky A, Tilghman S, Tjian R, Vale R, Wolberger C, Zakian V. PMID: 28912235.
      View in: PubMed   Mentions:    Fields:    
    34. Disease-associated mutations in human BICD2 hyperactivate motility of dynein-dynactin. J Cell Biol. 2017 10 02; 216(10):3051-3060. Huynh W, Vale RD. PMID: 28883039; PMCID: PMC5626548.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    35. RNA phase transitions in repeat expansion disorders. Nature. 2017 06 08; 546(7657):243-247. Jain A, Vale RD. PMID: 28562589; PMCID: PMC5555642.
      View in: PubMed   Mentions: 337     Fields:    Translation:HumansCells
    36. Ten simple rules to consider regarding preprint submission. PLoS Comput Biol. 2017 May; 13(5):e1005473. Bourne PE, Polka JK, Vale RD, Kiley R. PMID: 28472041; PMCID: PMC5417409.
      View in: PubMed   Mentions: 27     Fields:    
    37. Architectures of Lipid Transport Systems for the Bacterial Outer Membrane. Cell. 2017 04 06; 169(2):273-285.e17. Ekiert DC, Bhabha G, Isom GL, Greenan G, Ovchinnikov S, Henderson IR, Cox JS, Vale RD. PMID: 28388411; PMCID: PMC5467742.
      View in: PubMed   Mentions: 91     Fields:    Translation:Cells
    38. A DNA-Based T Cell Receptor Reveals a Role for Receptor Clustering in Ligand Discrimination. Cell. 2017 03 23; 169(1):108-119.e20. Taylor MJ, Husain K, Gartner ZJ, Mayor S, Vale RD. PMID: 28340336; PMCID: PMC6934412.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    39. T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition. Science. 2017 03 31; 355(6332):1428-1433. Hui E, Cheung J, Zhu J, Su X, Taylor MJ, Wallweber HA, Sasmal DK, Huang J, Kim JM, Mellman I, Vale RD. PMID: 28280247; PMCID: PMC6286077.
      View in: PubMed   Mentions: 665     Fields:    Translation:HumansAnimalsCells
    40. Reconstitution of TCR Signaling Using Supported Lipid Bilayers. Methods Mol Biol. 2017; 1584:65-76. Su X, Ditlev JA, Rosen MK, Vale RD. PMID: 28255696; PMCID: PMC5633369.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    41. An acquisition and analysis pipeline for scanning angle interference microscopy. Nat Methods. 2016 10 31; 13(11):897-898. Carbone CB, Vale RD, Stuurman N. PMID: 27798596; PMCID: PMC5100979.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    42. Micro-Magellan: open-source, sample-adaptive, acquisition software for optical microscopy. Nat Methods. 2016 09 29; 13(10):807-809. Pinkard H, Stuurman N, Corbin K, Vale R, Krummel MF. PMID: 27684577; PMCID: PMC5100821.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    43. Assembly and activation of dynein-dynactin by the cargo adaptor protein Hook3. J Cell Biol. 2016 08 01; 214(3):309-18. Schroeder CM, Vale RD. PMID: 27482052; PMCID: PMC4970328.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    44. Impact of New Camera Technologies on Discoveries in Cell Biology. Biol Bull. 2016 08; 231(1):5-13. Stuurman N, Vale RD. PMID: 27638691; PMCID: PMC5100698.
      View in: PubMed   Mentions: 6     Fields:    
    45. Priority of discovery in the life sciences. Elife. 2016 06 16; 5. Vale RD, Hyman AA. PMID: 27310529; PMCID: PMC4911212.
      View in: PubMed   Mentions: 11     Fields:    
    46. SCIENTIFIC COMMUNITY. Preprints for the life sciences. Science. 2016 May 20; 352(6288):899-901. Berg JM, Bhalla N, Bourne PE, Chalfie M, Drubin DG, Fraser JS, Greider CW, Hendricks M, Jones C, Kiley R, King S, Kirschner MW, Krumholz HM, Lehmann R, Leptin M, Pulverer B, Rosenzweig B, Spiro JE, Stebbins M, Strasser C, Swaminathan S, Turner P, Vale RD, VijayRaghavan K, Wolberger C. PMID: 27199406.
      View in: PubMed   Mentions: 38     Fields:    
    47. Dynamics of Translation of Single mRNA Molecules In Vivo. Cell. 2016 May 05; 165(4):976-89. Yan X, Hoek TA, Vale RD, Tanenbaum ME. PMID: 27153498; PMCID: PMC4889334.
      View in: PubMed   Mentions: 182     Fields:    Translation:HumansCells
    48. Phosphorylation of β-Tubulin by the Down Syndrome Kinase, Minibrain/DYRK1a, Regulates Microtubule Dynamics and Dendrite Morphogenesis. Neuron. 2016 05 04; 90(3):551-63. Ori-McKenney KM, McKenney RJ, Huang HH, Li T, Meltzer S, Jan LY, Vale RD, Wiita AP, Jan YN. PMID: 27112495; PMCID: PMC4860041.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    49. Phase separation of signaling molecules promotes T cell receptor signal transduction. Science. 2016 Apr 29; 352(6285):595-9. Su X, Ditlev JA, Hui E, Xing W, Banjade S, Okrut J, King DS, Taunton J, Rosen MK, Vale RD. PMID: 27056844; PMCID: PMC4892427.
      View in: PubMed   Mentions: 432     Fields:    Translation:HumansCells
    50. Tyrosination of α-tubulin controls the initiation of processive dynein-dynactin motility. EMBO J. 2016 06 01; 35(11):1175-85. McKenney RJ, Huynh W, Vale RD, Sirajuddin M. PMID: 26968983; PMCID: PMC4888239.
      View in: PubMed   Mentions: 99     Fields:    Translation:AnimalsCells
    51. How Dynein Moves Along Microtubules. Trends Biochem Sci. 2016 Jan; 41(1):94-105. Bhabha G, Johnson GT, Schroeder CM, Vale RD. PMID: 26678005; PMCID: PMC4706479.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    52. Accelerating scientific publication in biology. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):13439-46. Vale RD. PMID: 26508643; PMCID: PMC4640799.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    53. iBioChina and iBiology: spreading scientific knowledge together. Sci China Life Sci. 2015 Nov; 58(11):1180-2. Dell KR, Vale RD. PMID: 26423567.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    54. Tracking Movements of the Microtubule Motors Kinesin and Dynein Using Total Internal Reflection Fluorescence Microscopy. Cold Spring Harb Protoc. 2015 Sep 01; 2015(9):pdb.prot086355. Yildiz A, Vale RD. PMID: 26330626.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    55. Microtubule nucleation at the centrosome and beyond. Nat Cell Biol. 2015 Sep; 17(9):1089-93. Petry S, Vale RD. PMID: 26316453.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    56. Total Internal Reflection Fluorescence Microscopy. Cold Spring Harb Protoc. 2015 Sep 01; 2015(9):pdb.top086348. Yildiz A, Vale RD. PMID: 26330632.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    57. Regulation of mRNA translation during mitosis. Elife. 2015 Aug 25; 4. Tanenbaum ME, Stern-Ginossar N, Weissman JS, Vale RD. PMID: 26305499; PMCID: PMC4548207.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    58. Clustering of a kinesin-14 motor enables processive retrograde microtubule-based transport in plants. Nat Plants. 2015 Jul; 1(7). Jonsson E, Yamada M, Vale RD, Goshima G. PMID: 26322239; PMCID: PMC4548964.
      View in: PubMed   Mentions: 31     Fields:    
    59. De novo mutations in KIF1A cause progressive encephalopathy and brain atrophy. Ann Clin Transl Neurol. 2015 Jun; 2(6):623-35. Esmaeeli Nieh S, Madou MR, Sirajuddin M, Fregeau B, McKnight D, Lexa K, Strober J, Spaeth C, Hallinan BE, Smaoui N, Pappas JG, Burrow TA, McDonald MT, Latibashvili M, Leshinsky-Silver E, Lev D, Blumkin L, Vale RD, Barkovich AJ, Sherr EH. PMID: 26125038; PMCID: PMC4479523.
      View in: PubMed   Mentions: 48     Fields:    
    60. HkRP3 is a microtubule-binding protein regulating lytic granule clustering and NK cell killing. J Immunol. 2015 Apr 15; 194(8):3984-96. Ham H, Huynh W, Schoon RA, Vale RD, Billadeau DD. PMID: 25762780; PMCID: PMC4390494.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    61. Allosteric communication in the dynein motor domain. Cell. 2014 Nov 06; 159(4):857-68. Bhabha G, Cheng HC, Zhang N, Moeller A, Liao M, Speir JA, Cheng Y, Vale RD. PMID: 25417161; PMCID: PMC4269335.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    62. A protein-tagging system for signal amplification in gene expression and fluorescence imaging. Cell. 2014 Oct 23; 159(3):635-46. Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD. PMID: 25307933; PMCID: PMC4252608.
      View in: PubMed   Mentions: 576     Fields:    Translation:HumansAnimalsCells
    63. A Ras-like domain in the light intermediate chain bridges the dynein motor to a cargo-binding region. Elife. 2014 Oct 01; 3:e03351. Schroeder CM, Ostrem JM, Hertz NT, Vale RD. PMID: 25272277; PMCID: PMC4359372.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    64. Induction of focal adhesions and motility in Drosophila S2 cells. Mol Biol Cell. 2014 Dec 01; 25(24):3861-9. Ribeiro SA, D'Ambrosio MV, Vale RD. PMID: 25273555; PMCID: PMC4244196.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    65. Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes. Science. 2014 Jul 18; 345(6194):337-41. McKenney RJ, Huynh W, Tanenbaum ME, Bhabha G, Vale RD. PMID: 25035494; PMCID: PMC4224444.
      View in: PubMed   Mentions: 262     Fields:    Translation:HumansAnimalsCells
    66. Regulation of microtubule minus-end dynamics by CAMSAPs and Patronin. Proc Natl Acad Sci U S A. 2014 Apr 22; 111(16):5860-5. Hendershott MC, Vale RD. PMID: 24706919; PMCID: PMC4000804.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    67. Regulation of microtubule motors by tubulin isotypes and post-translational modifications. Nat Cell Biol. 2014 Apr; 16(4):335-44. Sirajuddin M, Rice LM, Vale RD. PMID: 24633327; PMCID: PMC4117587.
      View in: PubMed   Mentions: 266     Fields:    Translation:HumansAnimalsCells
    68. In vitro membrane reconstitution of the T-cell receptor proximal signaling network. Nat Struct Mol Biol. 2014 Feb; 21(2):133-42. Hui E, Vale RD. PMID: 24463463; PMCID: PMC4062301.
      View in: PubMed   Mentions: 78     Fields:    Translation:Cells
    69. A genome-wide screen identifies conserved protein hubs required for cadherin-mediated cell-cell adhesion. J Cell Biol. 2014 Jan 20; 204(2):265-79. Toret CP, D'Ambrosio MV, Vale RD, Simon MA, Nelson WJ. PMID: 24446484; PMCID: PMC3897182.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    70. Preface: the role of reconstitution in cytoskeleton research. Methods Enzymol. 2014; 540:xix-xxiii. Vale RD. PMID: 24630122.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    71. Advanced methods of microscope control using μManager software. J Biol Methods. 2014; 1(2). Edelstein AD, Tsuchida MA, Amodaj N, Pinkard H, Vale RD, Stuurman N. PMID: 25606571; PMCID: PMC4297649.
      View in: PubMed   Mentions: 729  
    72. Genes involved in centrosome-independent mitotic spindle assembly in Drosophila S2 cells. Proc Natl Acad Sci U S A. 2013 Dec 03; 110(49):19808-13. Moutinho-Pereira S, Stuurman N, Afonso O, Hornsveld M, Aguiar P, Goshima G, Vale RD, Maiato H. PMID: 24255106; PMCID: PMC3856817.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    73. Creating opportunities for science PhDs to pursue careers in high school education. Mol Biol Cell. 2013 Nov; 24(21):3292-6. Doyle KM, Vale RD. PMID: 24174464; PMCID: PMC3814146.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    74. Cytoplasmic dynein crosslinks and slides anti-parallel microtubules using its two motor domains. Elife. 2013 Sep 03; 2:e00943. Tanenbaum ME, Vale RD, McKenney RJ. PMID: 24015359; PMCID: PMC3762337.
      View in: PubMed   Mentions: 39     Fields:    Translation:Cells
    75. The value of asking questions. Mol Biol Cell. 2013 Mar; 24(6):680-2. Vale RD. PMID: 23486404; PMCID: PMC3596240.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    76. Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2. Cell. 2013 Feb 14; 152(4):768-77. Petry S, Groen AC, Ishihara K, Mitchison TJ, Vale RD. PMID: 23415226; PMCID: PMC3680348.
      View in: PubMed   Mentions: 176     Fields:    Translation:AnimalsCells
    77. Graduate education. Interdisciplinary graduate training in teaching labs. Science. 2012 Dec 21; 338(6114):1542-3. Vale RD, DeRisi J, Phillips R, Mullins RD, Waterman C, Mitchison TJ. PMID: 23258877; PMCID: PMC3810400.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    78. How lucky can one be? A perspective from a young scientist at the right place at the right time. Nat Med. 2012 Oct; 18(10):1486-8. Vale RD. PMID: 23042358.
      View in: PubMed   Mentions: 1     Fields:    
    79. Evaluating how we evaluate. Mol Biol Cell. 2012 Sep; 23(17):3285-9. Vale RD. PMID: 22936699; PMCID: PMC3431935.
      View in: PubMed   Mentions: 8     Fields:    
    80. Biophysical mechanism of T-cell receptor triggering in a reconstituted system. Nature. 2012 Jul 05; 487(7405):64-9. James JR, Vale RD. PMID: 22763440; PMCID: PMC3393772.
      View in: PubMed   Mentions: 174     Fields:    Translation:HumansCells
    81. Autophagy genes promote apoptotic cell corpse clearance. Autophagy. 2012 Aug; 8(8):1267-8. Zou W, Wang X, Vale RD, Ou G. PMID: 22653037.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    82. Autophagy genes function sequentially to promote apoptotic cell corpse degradation in the engulfing cell. J Cell Biol. 2012 Apr 02; 197(1):27-35. Li W, Zou W, Yang Y, Chai Y, Chen B, Cheng S, Tian D, Wang X, Vale RD, Ou G. PMID: 22451698; PMCID: PMC3317810.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    83. Cortical dynein controls microtubule dynamics to generate pulling forces that position microtubule asters. Cell. 2012 Feb 03; 148(3):502-14. Laan L, Pavin N, Husson J, Romet-Lemonne G, van Duijn M, López MP, Vale RD, Jülicher F, Reck-Peterson SL, Dogterom M. PMID: 22304918; PMCID: PMC3292199.
      View in: PubMed   Mentions: 187     Fields:    Translation:AnimalsCells
    84. A new cap for kinetochore fibre minus ends. Nat Cell Biol. 2011 Nov 13; 13(12):1389-91. Petry S, Vale RD. PMID: 22081093; PMCID: PMC3532025.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    85. The mechanism of dynein motility: insight from crystal structures of the motor domain. Biochim Biophys Acta. 2012 Jan; 1823(1):182-91. Cho C, Vale RD. PMID: 22062687; PMCID: PMC3249483.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    86. Augmin promotes meiotic spindle formation and bipolarity in Xenopus egg extracts. Proc Natl Acad Sci U S A. 2011 Aug 30; 108(35):14473-8. Petry S, Pugieux C, Nédélec FJ, Vale RD. PMID: 21844347; PMCID: PMC3167534.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    87. The Arf GAP CNT-2 regulates the apoptotic fate in C. elegans asymmetric neuroblast divisions. Curr Biol. 2011 Jun 07; 21(11):948-54. Singhvi A, Teuliere J, Talavera K, Cordes S, Ou G, Vale RD, Prasad BC, Clark SG, Garriga G. PMID: 21596567; PMCID: PMC3109113.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    88. Crystal structure of the dynein motor domain. Science. 2011 Mar 04; 331(6021):1159-65. Carter AP, Cho C, Jin L, Vale RD. PMID: 21330489; PMCID: PMC3169322.
      View in: PubMed   Mentions: 126     Fields:    Translation:Cells
    89. Kinesin-73 is a processive motor that localizes to Rab5-containing organelles. J Biol Chem. 2011 Mar 04; 286(9):7457-67. Huckaba TM, Gennerich A, Wilhelm JE, Chishti AH, Vale RD. PMID: 21169635; PMCID: PMC3045001.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    90. Imaging T-cell receptor activation reveals accumulation of tyrosine-phosphorylated CD3ζ in the endosomal compartment. Proc Natl Acad Sci U S A. 2010 Dec 21; 107(51):22128-33. Yudushkin IA, Vale RD. PMID: 21135224; PMCID: PMC3009781.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    91. A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis. J Cell Biol. 2010 Nov 01; 191(3):471-8. D'Ambrosio MV, Vale RD. PMID: 21041442; PMCID: PMC3003316.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    92. Patronin regulates the microtubule network by protecting microtubule minus ends. Cell. 2010 Oct 15; 143(2):263-74. Goodwin SS, Vale RD. PMID: 20946984; PMCID: PMC3008421.
      View in: PubMed   Mentions: 125     Fields:    Translation:AnimalsCells
    93. Computer control of microscopes using µManager. Curr Protoc Mol Biol. 2010 Oct; Chapter 14:Unit14.20. Edelstein A, Amodaj N, Hoover K, Vale R, Stuurman N. PMID: 20890901; PMCID: PMC3065365.
      View in: PubMed   Mentions: 818     Fields:    
    94. Polarized myosin produces unequal-size daughters during asymmetric cell division. Science. 2010 Oct 29; 330(6004):677-80. Ou G, Stuurman N, D'Ambrosio M, Vale RD. PMID: 20929735; PMCID: PMC3032534.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    95. Young leaders for biology in India. Science. 2010 Sep 17; 329(5998):1441. Tole S, Vale RD. PMID: 20847237.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    96. Altered actin centripetal retrograde flow in physically restricted immunological synapses. PLoS One. 2010 Jul 29; 5(7):e11878. Yu CH, Wu HJ, Kaizuka Y, Vale RD, Groves JT. PMID: 20686692; PMCID: PMC2912367.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    97. Determinants of myosin II cortical localization during cytokinesis. Curr Biol. 2010 Jun 22; 20(12):1080-5. Uehara R, Goshima G, Mabuchi I, Vale RD, Spudich JA, Griffis ER. PMID: 20541410; PMCID: PMC2930192.
      View in: PubMed   Mentions: 46     Fields:    Translation:Cells
    98. Communication between the AAA+ ring and microtubule-binding domain of dynein. Biochem Cell Biol. 2010 Feb; 88(1):15-21. Carter AP, Vale RD. PMID: 20130675; PMCID: PMC2894566.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    99. It's a wonderful life: a career as an academic scientist. Mol Biol Cell. 2010 Jan 01; 21(1):11-4. Vale RD. PMID: 20048258; PMCID: PMC2801704.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    100. Regulators of the cytoplasmic dynein motor. Nat Rev Mol Cell Biol. 2009 Dec; 10(12):854-65. Kardon JR, Vale RD. PMID: 19935668; PMCID: PMC3394690.
      View in: PubMed   Mentions: 320     Fields:    Translation:HumansAnimalsCells
    101. Dynamics of myosin, microtubules, and Kinesin-6 at the cortex during cytokinesis in Drosophila S2 cells. J Cell Biol. 2009 Sep 07; 186(5):727-38. Vale RD, Spudich JA, Griffis ER. PMID: 19720876; PMCID: PMC2742194.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    102. Introducing simulated cellular architecture to the quantitative analysis of fluorescent microscopy. Prog Biophys Mol Biol. 2009 Sep-Oct; 100(1-3):25-32. DePristo MA, Chang L, Vale RD, Khan SM, Lipkow K. PMID: 19628003; PMCID: PMC2805826.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    103. The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells. J Cell Biol. 2009 May 04; 185(3):521-34. Kaizuka Y, Douglass AD, Vardhana S, Dustin ML, Vale RD. PMID: 19398758; PMCID: PMC2700390.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    104. The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells. Proc Natl Acad Sci U S A. 2009 Apr 28; 106(17):6998-7003. Uehara R, Nozawa RS, Tomioka A, Petry S, Vale RD, Obuse C, Goshima G. PMID: 19369198; PMCID: PMC2668966.
      View in: PubMed   Mentions: 132     Fields:    Translation:HumansAnimalsCells
    105. Molecular signatures of cell migration in C. elegans Q neuroblasts. J Cell Biol. 2009 Apr 06; 185(1):77-85. Ou G, Vale RD. PMID: 19349580; PMCID: PMC2700521.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    106. Regulation of the processivity and intracellular localization of Saccharomyces cerevisiae dynein by dynactin. Proc Natl Acad Sci U S A. 2009 Apr 07; 106(14):5669-74. Kardon JR, Reck-Peterson SL, Vale RD. PMID: 19293377; PMCID: PMC2657088.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    107. The biological sciences in India: aiming high for the future. J Cell Biol. 2009 Feb 09; 184(3):342-53. Vale RD, Dell K. PMID: 19204144; PMCID: PMC2646550.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    108. Walking the walk: how kinesin and dynein coordinate their steps. Curr Opin Cell Biol. 2009 Feb; 21(1):59-67. Gennerich A, Vale RD. PMID: 19179063; PMCID: PMC2668149.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansCells
    109. Structure and functional role of dynein's microtubule-binding domain. Science. 2008 Dec 12; 322(5908):1691-5. Carter AP, Garbarino JE, Wilson-Kubalek EM, Shipley WE, Cho C, Milligan RA, Vale RD, Gibbons IR. PMID: 19074350; PMCID: PMC2663340.
      View in: PubMed   Mentions: 121     Fields:    Translation:AnimalsCells
    110. Microscopes for fluorimeters: the era of single molecule measurements. Cell. 2008 Nov 28; 135(5):779-85. Vale RD. PMID: 19041739; PMCID: PMC2762818.
      View in: PubMed   Mentions: 12     Fields:    
    111. Intramolecular strain coordinates kinesin stepping behavior along microtubules. Cell. 2008 Sep 19; 134(6):1030-41. Yildiz A, Tomishige M, Gennerich A, Vale RD. PMID: 18805095; PMCID: PMC2613771.
      View in: PubMed   Mentions: 126     Fields:    Translation:AnimalsCells
    112. Regulatory ATPase sites of cytoplasmic dynein affect processivity and force generation. J Biol Chem. 2008 Sep 19; 283(38):25839-45. Cho C, Reck-Peterson SL, Vale RD. PMID: 18650442; PMCID: PMC2533788.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    113. Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle. J Cell Biol. 2008 May 05; 181(3):421-9. Goshima G, Mayer M, Zhang N, Stuurman N, Vale RD. PMID: 18443220; PMCID: PMC2364697.
      View in: PubMed   Mentions: 198     Fields:    Translation:HumansAnimalsCells
    114. Mob4 plays a role in spindle focusing in Drosophila S2 cells. J Cell Sci. 2008 Apr 15; 121(Pt 8):1284-92. Trammell MA, Mahoney NM, Agard DA, Vale RD. PMID: 18388316; PMCID: PMC2851640.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    115. Functional genomic screen reveals genes involved in lipid-droplet formation and utilization. Nature. 2008 May 29; 453(7195):657-61. Guo Y, Walther TC, Rao M, Stuurman N, Goshima G, Terayama K, Wong JS, Vale RD, Walter P, Farese RV. PMID: 18408709; PMCID: PMC2734507.
      View in: PubMed   Mentions: 331     Fields:    Translation:AnimalsCells
    116. Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin. Nature. 2008 Jan 17; 451(7176):363-7. Roll-Mecak A, Vale RD. PMID: 18202664; PMCID: PMC2882799.
      View in: PubMed   Mentions: 168     Fields:    Translation:HumansAnimalsCells
    117. Single-molecule imaging of fluorescent proteins. Methods Cell Biol. 2008; 85:113-25. Douglass AD, Vale RD. PMID: 18155461.
      View in: PubMed   Mentions: 11     Fields:    
    118. Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells. Proc Natl Acad Sci U S A. 2007 Dec 18; 104(51):20296-301. Kaizuka Y, Douglass AD, Varma R, Dustin ML, Vale RD. PMID: 18077330; PMCID: PMC2154425.
      View in: PubMed   Mentions: 214     Fields:    Translation:HumansCells
    119. Force-induced bidirectional stepping of cytoplasmic dynein. Cell. 2007 Nov 30; 131(5):952-65. Gennerich A, Carter AP, Reck-Peterson SL, Vale RD. PMID: 18045537; PMCID: PMC2851641.
      View in: PubMed   Mentions: 178     Fields:    Translation:AnimalsCells
    120. How kinesin waits between steps. Nature. 2007 Nov 29; 450(7170):750-4. Mori T, Vale RD, Tomishige M. PMID: 18004302.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    121. Quantification and modeling of tripartite CD2-, CD58FC chimera (alefacept)-, and CD16-mediated cell adhesion. J Biol Chem. 2007 Nov 30; 282(48):34748-57. Dustin ML, Starr T, Coombs D, Majeau GR, Meier W, Hochman PS, Douglass A, Vale R, Goldstein B, Whitty A. PMID: 17911103.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    122. Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1. Mol Cell. 2007 Sep 21; 27(6):976-91. Slep KC, Vale RD. PMID: 17889670; PMCID: PMC2052927.
      View in: PubMed   Mentions: 149     Fields:    Translation:HumansAnimalsCells
    123. Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore. J Cell Biol. 2007 Jun 18; 177(6):1005-15. Griffis ER, Stuurman N, Vale RD. PMID: 17576797; PMCID: PMC2064361.
      View in: PubMed   Mentions: 130     Fields:    Translation:AnimalsCells
    124. Genes required for mitotic spindle assembly in Drosophila S2 cells. Science. 2007 Apr 20; 316(5823):417-21. Goshima G, Wollman R, Goodwin SS, Zhang N, Scholey JM, Vale RD, Stuurman N. PMID: 17412918; PMCID: PMC2837481.
      View in: PubMed   Mentions: 309     Fields:    Translation:AnimalsCells
    125. Making more microtubules by severing: a common theme of noncentrosomal microtubule arrays? J Cell Biol. 2006 Dec 18; 175(6):849-51. Roll-Mecak A, Vale RD. PMID: 17178905; PMCID: PMC2064694.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    126. Single-molecule observations of neck linker conformational changes in the kinesin motor protein. Nat Struct Mol Biol. 2006 Oct; 13(10):887-94. Tomishige M, Stuurman N, Vale RD. PMID: 17013387.
      View in: PubMed   Mentions: 44     Fields:    Translation:Cells
    127. Autoinhibition regulates the motility of the C. elegans intraflagellar transport motor OSM-3. J Cell Biol. 2006 Sep 25; 174(7):931-7. Imanishi M, Endres NF, Gennerich A, Vale RD. PMID: 17000874; PMCID: PMC2064385.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    128. Mechanism of transport of IFT particles in C. elegans cilia by the concerted action of kinesin-II and OSM-3 motors. J Cell Biol. 2006 Sep 25; 174(7):1035-45. Pan X, Ou G, Civelekoglu-Scholey G, Blacque OE, Endres NF, Tao L, Mogilner A, Leroux MR, Vale RD, Scholey JM. PMID: 17000880; PMCID: PMC2064394.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    129. Single-molecule analysis of dynein processivity and stepping behavior. Cell. 2006 Jul 28; 126(2):335-48. Reck-Peterson SL, Yildiz A, Carter AP, Gennerich A, Zhang N, Vale RD. PMID: 16873064; PMCID: PMC2851639.
      View in: PubMed   Mentions: 274     Fields:    Translation:AnimalsCells
    130. Making microtubules and mitotic spindles in cells without functional centrosomes. Curr Biol. 2006 Mar 21; 16(6):564-9. Mahoney NM, Goshima G, Douglass AD, Vale RD. PMID: 16546079.
      View in: PubMed   Mentions: 105     Fields:    Translation:AnimalsCells
    131. A lever-arm rotation drives motility of the minus-end-directed kinesin Ncd. Nature. 2006 Feb 16; 439(7078):875-8. Endres NF, Yoshioka C, Milligan RA, Vale RD. PMID: 16382238; PMCID: PMC2851630.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    132. Unbiased selection of localization elements reveals cis-acting determinants of mRNA bud localization in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2005 Dec 13; 102(50):18005-10. Jambhekar A, McDermott K, Sorber K, Shepard KA, Vale RD, Takizawa PA, DeRisi JL. PMID: 16326802; PMCID: PMC1298916.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    133. Length control of the metaphase spindle. Curr Biol. 2005 Nov 22; 15(22):1979-88. Goshima G, Wollman R, Stuurman N, Scholey JM, Vale RD. PMID: 16303556.
      View in: PubMed   Mentions: 135     Fields:    Translation:AnimalsCells
    134. Mechanisms for focusing mitotic spindle poles by minus end-directed motor proteins. J Cell Biol. 2005 Oct 24; 171(2):229-40. Goshima G, Nédélec F, Vale RD. PMID: 16247025; PMCID: PMC2171195.
      View in: PubMed   Mentions: 131     Fields:    Translation:AnimalsCells
    135. Use of RNA interference in Drosophila S2 cells to identify host pathways controlling compartmentalization of an intracellular pathogen. Proc Natl Acad Sci U S A. 2005 Sep 20; 102(38):13646-51. Cheng LW, Viala JP, Stuurman N, Wiedemann U, Vale RD, Portnoy DA. PMID: 16157870; PMCID: PMC1224656.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    136. Distinct pathways control recruitment and maintenance of myosin II at the cleavage furrow during cytokinesis. Proc Natl Acad Sci U S A. 2005 Sep 20; 102(38):13473-8. Dean SO, Rogers SL, Stuurman N, Vale RD, Spudich JA. PMID: 16174742; PMCID: PMC1200093.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    137. Distinct mechanisms govern the localisation of Drosophila CLIP-190 to unattached kinetochores and microtubule plus-ends. J Cell Sci. 2005 Aug 15; 118(Pt 16):3781-90. Dzhindzhev NS, Rogers SL, Vale RD, Ohkura H. PMID: 16105886.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    138. Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells. Cell. 2005 Jun 17; 121(6):937-50. Douglass AD, Vale RD. PMID: 15960980; PMCID: PMC2851620.
      View in: PubMed   Mentions: 326     Fields:    Translation:HumansCells
    139. Cell cycle-dependent dynamics and regulation of mitotic kinesins in Drosophila S2 cells. Mol Biol Cell. 2005 Aug; 16(8):3896-907. Goshima G, Vale RD. PMID: 15958489; PMCID: PMC1182325.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    140. The Drosophila homologue of the hereditary spastic paraplegia protein, spastin, severs and disassembles microtubules. Curr Biol. 2005 Apr 12; 15(7):650-5. Roll-Mecak A, Vale RD. PMID: 15823537.
      View in: PubMed   Mentions: 92     Fields:    Translation:AnimalsCells
    141. The affinity of the dynein microtubule-binding domain is modulated by the conformation of its coiled-coil stalk. J Biol Chem. 2005 Jun 24; 280(25):23960-5. Gibbons IR, Garbarino JE, Tan CE, Reck-Peterson SL, Vale RD, Carter AP. PMID: 15826937; PMCID: PMC1464088.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    142. Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase. Nat Cell Biol. 2005 Mar; 7(3):235-45. Mennella V, Rogers GC, Rogers SL, Buster DW, Vale RD, Sharp DJ. PMID: 15723056.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    143. Structural determinants for EB1-mediated recruitment of APC and spectraplakins to the microtubule plus end. J Cell Biol. 2005 Feb 14; 168(4):587-98. Slep KC, Rogers SL, Elliott SL, Ohkura H, Kolodziej PA, Vale RD. PMID: 15699215; PMCID: PMC2171753.
      View in: PubMed   Mentions: 101     Fields:    Translation:AnimalsCells
    144. Drosophila RhoGEF2 associates with microtubule plus ends in an EB1-dependent manner. Curr Biol. 2004 Oct 26; 14(20):1827-33. Rogers SL, Wiedemann U, Häcker U, Turck C, Vale RD. PMID: 15498490.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    145. A standardized kinesin nomenclature. J Cell Biol. 2004 Oct 11; 167(1):19-22. Lawrence CJ, Dawe RK, Christie KR, Cleveland DW, Dawson SC, Endow SA, Goldstein LS, Goodson HV, Hirokawa N, Howard J, Malmberg RL, McIntosh JR, Miki H, Mitchison TJ, Okada Y, Reddy AS, Saxton WM, Schliwa M, Scholey JM, Vale RD, Walczak CE, Wordeman L. PMID: 15479732; PMCID: PMC2041940.
      View in: PubMed   Mentions: 308     Fields:    Translation:HumansAnimals
    146. Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2004 Sep 28; 101(39):14305. Reck-Peterson SL, Vale RD. PMID: 15693149; PMCID: PMC521152.
      View in: PubMed   Mentions: 2     Fields:    
    147. Mechanism of prion propagation: amyloid growth occurs by monomer addition. PLoS Biol. 2004 Oct; 2(10):e321. Collins SR, Douglass A, Vale RD, Weissman JS. PMID: 15383837; PMCID: PMC517824.
      View in: PubMed   Mentions: 199     Fields:    
    148. The lipid binding pleckstrin homology domain in UNC-104 kinesin is necessary for synaptic vesicle transport in Caenorhabditis elegans. Mol Biol Cell. 2004 Aug; 15(8):3729-39. Klopfenstein DR, Vale RD. PMID: 15155810; PMCID: PMC491832.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    149. A tribute to Shinya Inoue and innovation in light microscopy. J Cell Biol. 2004 Apr; 165(1):21-5. Dell KR, Vale RD. PMID: 15317131; PMCID: PMC2172095.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    150. Molecular dissection of the roles of nucleotide binding and hydrolysis in dynein's AAA domains in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2004 Feb 10; 101(6):1491-5. Reck-Peterson SL, Vale RD. PMID: 14755060; PMCID: PMC341754.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    151. Kinesin walks hand-over-hand. Science. 2004 Jan 30; 303(5658):676-8. Yildiz A, Tomishige M, Vale RD, Selvin PR. PMID: 14684828.
      View in: PubMed   Mentions: 318     Fields:    Translation:HumansCells
    152. Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase. Nature. 2004 Jan 22; 427(6972):364-70. Rogers GC, Rogers SL, Schwimmer TA, Ems-McClung SC, Walczak CE, Vale RD, Scholey JM, Sharp DJ. PMID: 14681690.
      View in: PubMed   Mentions: 163     Fields:    Translation:AnimalsCells
    153. Distinct conformations of the kinesin Unc104 neck regulate a monomer to dimer motor transition. J Cell Biol. 2003 Nov 24; 163(4):743-53. Al-Bassam J, Cui Y, Klopfenstein D, Carragher BO, Vale RD, Milligan RA. PMID: 14638858; PMCID: PMC2173678.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    154. Myosin V motor proteins: marching stepwise towards a mechanism. J Cell Biol. 2003 Nov 10; 163(3):445-50. Vale RD. PMID: 14610051; PMCID: PMC2173644.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    155. The roles of microtubule-based motor proteins in mitosis: comprehensive RNAi analysis in the Drosophila S2 cell line. J Cell Biol. 2003 Sep 15; 162(6):1003-16. Goshima G, Vale RD. PMID: 12975346; PMCID: PMC2172859.
      View in: PubMed   Mentions: 190     Fields:    Translation:AnimalsCells
    156. Molecular requirements for actin-based lamella formation in Drosophila S2 cells. J Cell Biol. 2003 Sep 15; 162(6):1079-88. Rogers SL, Wiedemann U, Stuurman N, Vale RD. PMID: 12975351; PMCID: PMC2172842.
      View in: PubMed   Mentions: 214     Fields:    Translation:AnimalsCells
    157. Mitochondrial positioning in fission yeast is driven by association with dynamic microtubules and mitotic spindle poles. Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20):11424-8. Yaffe MP, Stuurman N, Vale RD. PMID: 12972644; PMCID: PMC208773.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    158. Drosophila pod-1 crosslinks both actin and microtubules and controls the targeting of axons. Neuron. 2003 Aug 28; 39(5):779-91. Rothenberg ME, Rogers SL, Vale RD, Jan LY, Jan YN. PMID: 12948445.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    159. Closing of the nucleotide pocket of kinesin-family motors upon binding to microtubules. Science. 2003 May 02; 300(5620):798-801. Naber N, Minehardt TJ, Rice S, Chen X, Grammer J, Matuska M, Vale RD, Kollman PA, Car R, Yount RG, Cooke R, Pate E. PMID: 12730601.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    160. EPR spectroscopy shows a microtubule-dependent conformational change in the kinesin switch 1 domain. Biophys J. 2003 May; 84(5):3190-6. Naber N, Rice S, Matuska M, Vale RD, Cooke R, Pate E. PMID: 12719248; PMCID: PMC1302879.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    161. The molecular motor toolbox for intracellular transport. Cell. 2003 Feb 21; 112(4):467-80. Vale RD. PMID: 12600311.
      View in: PubMed   Mentions: 662     Fields:    Translation:HumansAnimalsCells
    162. Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle. J Cell Biol. 2002 Sep 02; 158(5):873-84. Rogers SL, Rogers GC, Sharp DJ, Vale RD. PMID: 12213835; PMCID: PMC2173155.
      View in: PubMed   Mentions: 184     Fields:    Translation:AnimalsCells
    163. Role of phosphatidylinositol(4,5)bisphosphate organization in membrane transport by the Unc104 kinesin motor. Cell. 2002 May 03; 109(3):347-58. Klopfenstein DR, Tomishige M, Stuurman N, Vale RD. PMID: 12015984; PMCID: PMC2851634.
      View in: PubMed   Mentions: 128     Fields:    Translation:AnimalsCells
    164. The Khd1 protein, which has three KH RNA-binding motifs, is required for proper localization of ASH1 mRNA in yeast. EMBO J. 2002 Mar 01; 21(5):1158-67. Irie K, Tadauchi T, Takizawa PA, Vale RD, Matsumoto K, Herskowitz I. PMID: 11867544; PMCID: PMC125877.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    165. Kinesin motors and microtubule-based organelle transport in Dictyostelium discoideum. J Muscle Res Cell Motil. 2002; 23(7-8):631-8. Klopfenstein DR, Holleran EA, Vale RD. PMID: 12952062.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
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