-
Defining pathogenic IL-17 and CSF-1 gene expression signatures in chronic graft-versus-host disease. Blood. 2025 Feb 20.
Boiko JR, Ensbey KS, Waltner OG, Jenkins IC, Bhise SS, MacDonald KP, Blazar BR, Hall AM, Gooley TA, Minnie SA, Lee SJ, Furlan SN, Hill GR. PMID: 39977705.
View in:
PubMed Mentions:
-
Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD. Reply. J Clin Invest. 2024 Oct 15; 134(20).
Zhang P, Minnie SA, Hill GR. PMID: 39403932; PMCID: PMC11473142.
View in:
PubMed Mentions:
-
Microbiota dictate T cell clonal selection to augment graft-versus-host disease after stem cell transplantation. Immunity. 2024 07 09; 57(7):1648-1664.e9.
Yeh AC, Koyama M, Waltner OG, Minnie SA, Boiko JR, Shabaneh TB, Takahashi S, Zhang P, Ensbey KS, Schmidt CR, Legg SRW, Sekiguchi T, Nelson E, Bhise SS, Stevens AR, Goodpaster T, Chakka S, Furlan SN, Markey KA, Bleakley ME, Elson CO, Bradley PH, Hill GR. PMID: 38876098; PMCID: PMC11236519.
View in:
PubMed Mentions:
-
Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD. J Clin Invest. 2024 Jun 03; 134(11).
Wang Y, Ullah MA, Waltner OG, Bhise SS, Ensbey KS, Schmidt CR, Legg SR, Sekiguchi T, Nelson EL, Kuns RD, Nemychenkov NS, Atilla E, Yeh AC, Takahashi S, Boiko JR, Varelias A, Blazar BR, Koyama M, Minnie SA, Clouston AD, Furlan SN, Zhang P, Hill GR. PMID: 38828727; PMCID: PMC11142741.
View in:
PubMed Mentions:
-
TIM-3+ CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies. Sci Immunol. 2024 04 19; 9(94):eadg1094.
Minnie SA, Waltner OG, Zhang P, Takahashi S, Nemychenkov NS, Ensbey KS, Schmidt CR, Legg SRW, Comstock M, Boiko JR, Nelson E, Bhise SS, Wilkens AB, Koyama M, Dhodapkar MV, Chesi M, Riddell SR, Green DJ, Spencer A, Furlan SN, Hill GR. PMID: 38640253; PMCID: PMC11093588.
View in:
PubMed Mentions:
-
Regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation. Blood. 2024 04 18; 143(16):1656-1669.
Takahashi S, Minnie SA, Ensbey KS, Schmidt CR, Sekiguchi T, Legg SRW, Zhang P, Koyama M, Olver SD, Collinge AD, Keshmiri S, Comstock ML, Varelias A, Green DJ, Hill GR. PMID: 38295333; PMCID: PMC11103090.
View in:
PubMed Mentions:
-
IL-6-mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation. J Clin Invest. 2024 Apr 01; 134(7).
Zhang P, Fleming P, Andoniou CE, Waltner OG, Bhise SS, Martins JP, McEnroe BA, Voigt V, Daly S, Kuns RD, Ekwe AP, Henden AS, Saldan A, Olver S, Varelias A, Smith C, Schmidt CR, Ensbey KS, Legg SR, Sekiguchi T, Minnie SA, Gradwell M, Wagenaar I, Clouston AD, Koyama M, Furlan SN, Kennedy GA, Ward ES, Degli-Esposti MA, Hill GR, Tey SK. PMID: 38557487; PMCID: PMC10977988.
View in:
PubMed Mentions:
-
Intestinal microbiota controls graft-versus-host disease independent of donor-host genetic disparity. Immunity. 2023 08 08; 56(8):1876-1893.e8.
Koyama M, Hippe DS, Srinivasan S, Proll SC, Miltiadous O, Li N, Zhang P, Ensbey KS, Hoffman NG, Schmidt CR, Yeh AC, Minnie SA, Strenk SM, Fiedler TL, Hattangady N, Kowalsky J, Grady WM, Degli-Esposti MA, Varelias A, Clouston AD, van den Brink MRM, Dey N, Randolph TW, Markey KA, Fredricks DN, Hill GR. PMID: 37480848; PMCID: PMC10530372.
View in:
PubMed Mentions:
-
Oncogenic drivers dictate immune control of acute myeloid leukemia. Nat Commun. 2023 04 14; 14(1):2155.
Austin RJ, Straube J, Halder R, Janardhanan Y, Bruedigam C, Witkowski M, Cooper L, Porter A, Braun M, Souza-Fonseca-Guimaraes F, Minnie SA, Cooper E, Jacquelin S, Song A, Bald T, Nakamura K, Hill GR, Aifantis I, Lane SW, Bywater MJ. PMID: 37059710; PMCID: PMC10104832.
View in:
PubMed Mentions:
-
Multiparametric flow cytometry to characterize vaccine-induced polyfunctional T cell responses and T cell/NK cell exhaustion and memory phenotypes in mouse immuno-oncology models. Front Immunol. 2023; 14:1127896.
Moi D, Zeng B, Minnie SA, Bhatt R, Wood J, Sester DP, Mazzieri R, Dolcetti R. PMID: 37090730; PMCID: PMC10115975.
View in:
PubMed Mentions:
-
TIGIT inhibition and lenalidomide synergistically promote antimyeloma immune responses after stem cell transplantation in mice. J Clin Invest. 2023 02 15; 133(4).
Minnie SA, Waltner OG, Ensbey KS, Olver SD, Collinge AD, Sester DP, Schmidt CR, Legg SR, Takahashi S, Nemychenkov NS, Sekiguchi T, Driessens G, Zhang P, Koyama M, Spencer A, Holmberg LA, Furlan SN, Varelias A, Hill GR. PMID: 36512425; PMCID: PMC9927935.
View in:
PubMed Mentions:
-
Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity. Sci Immunol. 2022 10 21; 7(76):eabo3420.
Minnie SA, Waltner OG, Ensbey KS, Nemychenkov NS, Schmidt CR, Bhise SS, Legg SRW, Campoy G, Samson LD, Kuns RD, Zhou T, Huck JD, Vuckovic S, Zamora D, Yeh A, Spencer A, Koyama M, Markey KA, Lane SW, Boeckh M, Ring AM, Furlan SN, Hill GR. PMID: 36240285; PMCID: PMC10184646.
View in:
PubMed Mentions:
-
Peritransplant glucocorticoids redistribute donor T cells to the bone marrow and prevent relapse after haploidentical SCT. JCI Insight. 2021 11 22; 6(22).
Inoue T, Koyama M, Kaida K, Ikegame K, Ensbey KS, Samson L, Takahashi S, Zhang P, Minnie SA, Maruyama S, Ishii S, Daimon T, Fukuda T, Nakamae H, Ara T, Maruyama Y, Ishiyama K, Ichinohe T, Atsuta Y, Blazar BR, Furlan SN, Ogawa H, Hill GR. PMID: 34637399; PMCID: PMC8663779.
View in:
PubMed Mentions:
-
Autologous Stem Cell Transplantation for Myeloma: Cytoreduction or an Immunotherapy? Front Immunol. 2021; 12:651288.
Minnie SA, Hill GR. PMID: 33777050; PMCID: PMC7994609.
View in:
PubMed Mentions:
-
Immunotherapy of multiple myeloma. J Clin Invest. 2020 04 01; 130(4):1565-1575.
Minnie SA, Hill GR. PMID: 32149732; PMCID: PMC7108923.
View in:
PubMed Mentions:
-
IL-6 dysregulation originates in dendritic cells and mediates graft-versus-host disease via classical signaling. Blood. 2019 12 05; 134(23):2092-2106.
Wilkinson AN, Chang K, Kuns RD, Henden AS, Minnie SA, Ensbey KS, Clouston AD, Zhang P, Koyama M, Hidalgo J, Rose-John S, Varelias A, Vuckovic S, Gartlan KH, Hill GR. PMID: 31578204.
View in:
PubMed Mentions:
-
Bone marrow transplantation generates T cell-dependent control of myeloma in mice. J Clin Invest. 2019 01 02; 129(1):106-121.
Vuckovic S, Minnie SA, Smith D, Gartlan KH, Watkins TS, Markey KA, Mukhopadhyay P, Guillerey C, Kuns RD, Locke KR, Pritchard AL, Johansson PA, Varelias A, Zhang P, Huntington ND, Waddell N, Chesi M, Miles JJ, Smyth MJ, Hill GR. PMID: 30300141; PMCID: PMC6307976.
View in:
PubMed Mentions:
-
Myeloma escape after stem cell transplantation is a consequence of T-cell exhaustion and is prevented by TIGIT blockade. Blood. 2018 10 18; 132(16):1675-1688.
Minnie SA, Kuns RD, Gartlan KH, Zhang P, Wilkinson AN, Samson L, Guillerey C, Engwerda C, MacDonald KPA, Smyth MJ, Markey KA, Vuckovic S, Hill GR. PMID: 30154111.
View in:
PubMed Mentions:
-
TIGIT immune checkpoint blockade restores CD8+ T-cell immunity against multiple myeloma. Blood. 2018 10 18; 132(16):1689-1694.
Guillerey C, Harjunpää H, Carrié N, Kassem S, Teo T, Miles K, Krumeich S, Weulersse M, Cuisinier M, Stannard K, Yu Y, Minnie SA, Hill GR, Dougall WC, Avet-Loiseau H, Teng MWL, Nakamura K, Martinet L, Smyth MJ. PMID: 29986909.
View in:
PubMed Mentions:
-
Flt-3L Expansion of Recipient CD8α+ Dendritic Cells Deletes Alloreactive Donor T Cells and Represents an Alternative to Posttransplant Cyclophosphamide for the Prevention of GVHD. Clin Cancer Res. 2018 04 01; 24(7):1604-1616.
Markey KA, Kuns RD, Browne DJ, Gartlan KH, Robb RJ, Martins JP, Henden AS, Minnie SA, Cheong M, Koyama M, Smyth MJ, Steptoe RJ, Belz GT, Brocker T, Degli-Esposti MA, Lane SW, Hill GR. PMID: 29367429.
View in:
PubMed Mentions: