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MRD-negative duration following latest line of therapy predicts long-term PFS in real-world patients with multiple myeloma. Blood Adv. 2025 Jan 14; 9(1):176-179.
Chen LY, Thibaud S, Bodnar S, Chari A, Richter J, Cho HJ, Sanchez LJ, Rodriguez C, Rossi AC, Richard S, Parekh S, Jagannath S. PMID: 39546749.
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PubMed Mentions: Fields:
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Efficacy and Safety of Daratumumab in Intermediate/High-risk Smoldering Multiple Myeloma: Final Analysis of CENTAURUS. Blood. 2024 Dec 09.
Landgren CO, Chari A, Cohen YC, Spencer A, Voorhees PM, Sandhu I, Jenner MW, Smith D, Cavo M, van de Donk NWCJ, Beksac M, Moreau P, Goldschmidt H, Vieyra D, Sha L, Li L, Rousseau E, Dennis RM, Carson R, Hofmeister CC. PMID: 39652826.
View in:
PubMed Mentions: Fields:
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Multiple Myeloma Risk and Outcomes Are Associated with Pathogenic Germline Variants in DNA Repair Genes. Blood Cancer Discov. 2024 Nov 01; 5(6):428-441.
Thibaud S, Subaran RL, Newman S, Lagana A, Melnekoff DT, Bodnar S, Ram M, Soens Z, Genthe W, Brander T, Mouhieddine TH, Van Oekelen O, Houldsworth J, Cho HJ, Richard S, Richter J, Rodriguez C, Rossi A, Sanchez L, Chari A, Moshier E, Jagannath S, Parekh S, Onel K. PMID: 39283238; PMCID: PMC11528192.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Author Correction: Mobilization strategies with and without plerixafor for autologous stem cell transplant in patients with multiple myeloma. Bone Marrow Transplant. 2024 Oct 18.
Avigan ZM, Arinsburg S, Pan D, Mark T, Fausel C, Bubalo J, Milkovich G, Moshier E, Fu W, Chari A, Richter J. PMID: 39424960.
View in:
PubMed Mentions: Fields:
-
Bispecific antibodies in the treatment of multiple myeloma. Blood Cancer J. 2024 09 12; 14(1):158.
Devasia AJ, Chari A, Lancman G. PMID: 39266530; PMCID: PMC11393350.
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PubMed Mentions: Fields:
Translation:
Humans
-
Matching-adjusted indirect comparison of talquetamab vs selinexor-dexamethasone and vs belantamab mafodotin in patients with relapsed/refractory multiple myeloma. Curr Med Res Opin. 2024 Oct; 40(10):1769-1783.
Reece D, Diels J, Van Sanden S, Pei L, Ammann E, Heuck C, Kane C, Londhe A, Peterson S, Chari A. PMID: 39226081.
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PubMed Mentions: Fields:
Translation:
HumansCTClinical Trials
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Comprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes. Nat Genet. 2024 Sep; 56(9):1878-1889.
Skerget S, Penaherrera D, Chari A, Jagannath S, Siegel DS, Vij R, Orloff G, Jakubowiak A, Niesvizky R, Liles D, Berdeja J, Levy M, Wolf J, Usmani SZ, MMRF CoMMpass Network, Christofferson AW, Nasser S, Aldrich JL, Legendre C, Benard B, Miller C, Turner B, Kurdoglu A, Washington M, Yellapantula V, Adkins JR, Cuyugan L, Boateng M, Helland A, Kyman S, McDonald J, Reiman R, Stephenson K, Tassone E, Blanski A, Livermore B, Kirchhoff M, Rohrer DC, D'Agostino M, Gamella M, Collison K, Stumph J, Kidd P, Donnelly A, Zaugg B, Toone M, McBride K, DeRome M, Rogers J, Craig D, Liang WS, Gutierrez NC, Jewell SD, Carpten J, Anderson KC, Cho HJ, Auclair D, Lonial S, Keats JJ. PMID: 39160255; PMCID: PMC11387199.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Mobilization strategies with and without plerixafor for autologous stem cell transplant in patients with multiple myeloma. Bone Marrow Transplant. 2024 Oct; 59(10):1440-1448.
Avigan ZM, Arinsburg S, Pan D, Mark T, Fausel C, Bubalo J, Milkovich G, Moshier E, Fu W, Chari A, Richter J. PMID: 39085373.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Mechanisms of resistance against T-cell engaging bispecific antibodies in multiple myeloma: implications for novel treatment strategies. Lancet Haematol. 2024 Sep; 11(9):e693-e707.
van de Donk NWCJ, Chari A, Mateos MV. PMID: 39033769.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Daratumumab in transplant-eligible patients with newly diagnosed multiple myeloma: final analysis of clinically relevant subgroups in GRIFFIN. Blood Cancer J. 2024 07 08; 14(1):107.
Chari A, Kaufman JL, Laubach J, Sborov DW, Reeves B, Rodriguez C, Silbermann R, Costa LJ, Anderson LD, Nathwani N, Shah N, Bumma N, Holstein SA, Costello C, Jakubowiak A, Wildes TM, Orlowski RZ, Shain KH, Cowan AJ, Pei H, Cortoos A, Patel S, Lin TS, Voorhees PM, Usmani SZ, Richardson PG. PMID: 38977707; PMCID: PMC11231363.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCTClinical Trials
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Clinical Management of Patients With Relapsed/Refractory Multiple Myeloma Treated With Talquetamab. Clin Lymphoma Myeloma Leuk. 2024 Oct; 24(10):665-693.e14.
Chari A, Krishnan A, Rasche L, Ye JC, Garfall A, Popat R, Lipe B, Qin X, Campagna M, Masterson T, Tomlinson C, Hilder B, Tolbert J, Renaud T, Smit MD, Gray K, Kane C, Heuck C, van de Donk NWCJ. PMID: 38871558.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCTClinical Trials
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Salvage therapies including retreatment with BCMA-directed approaches after BCMA CAR-T relapses for multiple myeloma. Blood Adv. 2024 05 14; 8(9):2207-2216.
Reyes KR, Liu YC, Huang CY, Banerjee R, Martin T, Wong SW, Wolf JL, Arora S, Shah N, Chari A, Chung A. PMID: 38429087; PMCID: PMC11061209.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
International Myeloma Working Group immunotherapy committee consensus guidelines and recommendations for optimal use of T-cell-engaging bispecific antibodies in multiple myeloma. Lancet Oncol. 2024 05; 25(5):e205-e216.
Rodriguez-Otero P, Usmani S, Cohen AD, van de Donk NWCJ, Leleu X, Gállego Pérez-Larraya J, Manier S, Nooka AK, Mateos MV, Einsele H, Minnema M, Cavo M, Derman BA, Puig N, Gay F, Ho PJ, Chng WJ, Kastritis E, Gahrton G, Weisel K, Nagarajan C, Schjesvold F, Mikhael J, Costa L, Raje NS, Zamagni E, Hájek R, Weinhold N, Yong K, Ye JC, Sidhana S, Merlini G, Martin T, Lin Y, Chari A, Popat R, Kaufman JL, International Myeloma Working Group. PMID: 38697166.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
-
Daratumumab-based quadruplet therapy for transplant-eligible newly diagnosed multiple myeloma with high cytogenetic risk. Blood Cancer J. 2024 04 22; 14(1):69.
Callander NS, Silbermann R, Kaufman JL, Godby KN, Laubach J, Schmidt TM, Sborov DW, Medvedova E, Reeves B, Dhakal B, Rodriguez C, Chhabra S, Chari A, Bal S, Anderson LD, Dholaria BR, Nathwani N, Hari P, Shah N, Bumma N, Holstein SA, Costello C, Jakubowiak A, Wildes TM, Orlowski RZ, Shain KH, Cowan AJ, Pei H, Cortoos A, Patel S, Lin TS, Giri S, Costa LJ, Usmani SZ, Richardson PG, Voorhees PM. PMID: 38649340; PMCID: PMC11035596.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Health-related quality of life in transplant-eligible patients with newly diagnosed multiple myeloma treated with daratumumab, lenalidomide, bortezomib, and dexamethasone: Patient-reported outcomes from GRIFFIN. Am J Hematol. 2024 07; 99(7):1257-1268.
Silbermann R, Laubach J, Kaufman JL, Sborov DW, Reeves B, Rodriguez C, Chari A, Costa LJ, Anderson LD, Nathwani N, Shah N, Bumma N, Holstein SA, Costello C, Jakubowiak A, Orlowski RZ, Shain KH, Cowan AJ, Gries KS, Pei H, Cortoos A, Patel S, Lin TS, Voorhees PM, Usmani SZ, Richardson PG. PMID: 38622840.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCTClinical Trials
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Phase 1 study combining elotuzumab with autologous stem cell transplant and lenalidomide for multiple myeloma. J Immunother Cancer. 2024 Apr 12; 12(4).
Coffey DG, Osman K, Aleman A, Bekri S, Kats S, Dhadwal A, Catamero D, Kim-Schulze S, Gnjatic S, Chari A, Parekh S, Jagannath S, Cho HJ. PMID: 38609316; PMCID: PMC11029259.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCellsCTClinical Trials
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Post hoc analysis of daratumumab plus lenalidomide, bortezomib and dexamethasone in Black patients from final data of the GRIFFIN study. Br J Haematol. 2024 Jun; 204(6):2227-2232.
Nooka AK, Kaufman JL, Rodriguez C, Jakubowiak A, Efebera Y, Reeves B, Wildes TM, Holstein SA, Anderson LD, Badros A, Shune L, Chari A, Pei H, Cortoos A, Patel S, Lin TS, Voorhees PM, Usmani SZ, Richardson PG. PMID: 38504552.
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PubMed Mentions: Fields:
Translation:
Humans
-
Correction: GPRC5D as a novel target for the treatment of multiple myeloma: a narrative review. Blood Cancer J. 2024 Mar 06; 14(1):40.
Rodriguez-Otero P, van de Donk NWCJ, Pillarisetti K, Cornax I, Vishwamitra D, Gray K, Hilder B, Tolbert J, Renaud T, Masterson T, Heuck C, Kane C, Verona R, Moreau P, Bahlis N, Chari A. PMID: 38448422; PMCID: PMC10918080.
View in:
PubMed Mentions: Fields:
-
GPRC5D as a novel target for the treatment of multiple myeloma: a narrative review. Blood Cancer J. 2024 02 02; 14(1):24.
Rodriguez-Otero P, van de Donk NWCJ, Pillarisetti K, Cornax I, Vishwamitra D, Gray K, Hilder B, Tolbert J, Renaud T, Masterson T, Heuck C, Kane C, Verona R, Moreau P, Bahlis N, Chari A. PMID: 38307865; PMCID: PMC10837198.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
Role of Consolidation and Maintenance. Hematol Oncol Clin North Am. 2024 04; 38(2):421-440.
Kumar AD, Chari A. PMID: 38262780.
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PubMed Mentions: Fields:
Translation:
Humans
-
Prevalence and impact of diabetes on survival of patients with multiple myeloma in different racial groups. Blood Adv. 2024 01 09; 8(1):236-247.
Shah UA, Moshier E, Derkach A, Huang Y, Mailankody S, Tan CR, Maclachlan K, Hultcrantz M, Korde N, Hassoun H, Thibaud S, Sanchez L, Rodriguez C, Richard S, Richter J, Rossi A, Cho HJ, Lesokhin A, Chari A, Usmani SZ, Jagannath S, Parekh S, Gallagher EJ. PMID: 37772981; PMCID: PMC10918423.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
-
Teclistamab Improves Patient-Reported Symptoms and Health-Related Quality of Life in Relapsed or Refractory Multiple Myeloma: Results From the Phase II MajesTEC-1 Study. Clin Lymphoma Myeloma Leuk. 2024 03; 24(3):194-202.
Martin TG, Moreau P, Usmani SZ, Garfall A, Mateos MV, San-Miguel JF, Oriol A, Nooka AK, Rosinol L, Chari A, Karlin L, Krishnan A, Bahlis N, Popat R, Besemer B, Martínez-López J, Delforge M, Trancucci D, Pei L, Kobos R, Fastenau J, Gries KS, van de Donk NWCJ. PMID: 38052709.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCTClinical Trials
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IVIg Use Associated with Ten-Fold Reduction of Serious Infections in Multiple Myeloma Patients Treated with Anti-BCMA Bispecific Antibodies. Blood Cancer Discov. 2023 11 01; 4(6):440-451.
Lancman G, Parsa K, Kotlarz K, Avery L, Lurie A, Lieberman-Cribbin A, Cho HJ, Parekh SS, Richard S, Richter J, Rodriguez C, Rossi A, Sanchez LJ, Thibaud S, Jagannath S, Chari A. PMID: 37769148; PMCID: PMC10618720.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
-
Comparison of health care costs and resource utilization for commonly used proteasome inhibitor-immunomodulatory drug-based triplet regimens for the management of patients with relapsed/refractory multiple myeloma in the United States. J Manag Care Spec Pharm. 2023 Nov; 29(11):1205-1218.
Sanchez L, Chari A, Cheng M, Cherepanov D, DerSarkissian M, Huang F, Stull DM, Dabora J, Young M, Noga SJ, Pi S, Zhang M, Banatwala A, Duh MS, Ailawadhi S. PMID: 37776124; PMCID: PMC10776283.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Addition of daratumumab to lenalidomide, bortezomib, and dexamethasone for transplantation-eligible patients with newly diagnosed multiple myeloma (GRIFFIN): final analysis of an open-label, randomised, phase 2 trial. Lancet Haematol. 2023 Oct; 10(10):e825-e837.
Voorhees PM, Sborov DW, Laubach J, Kaufman JL, Reeves B, Rodriguez C, Chari A, Silbermann R, Costa LJ, Anderson LD, Nathwani N, Shah N, Bumma N, Efebera YA, Holstein SA, Costello C, Jakubowiak A, Wildes TM, Orlowski RZ, Shain KH, Cowan AJ, Dinner S, Pei H, Cortoos A, Patel S, Lin TS, Usmani SZ, Richardson PG. PMID: 37708911.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCTClinical Trials
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Single-agent belantamab mafodotin in patients with relapsed/refractory multiple myeloma: Final analysis of the DREAMM-2 trial. Cancer. 2023 12 01; 129(23):3746-3760.
Nooka AK, Cohen AD, Lee HC, Badros A, Suvannasankha A, Callander N, Abdallah AO, Trudel S, Chari A, Libby EN, Chaudhry M, Hultcrantz M, Kortüm KM, Popat R, Sborov D, Hakim S, Lewis E, Gorsh B, Bhushan B, McKeown A, Gupta I, Opalinska J, Richardson PG, Lonial S. PMID: 37622738; PMCID: PMC11055177.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
Plain language summary of the MonumenTAL-1 study of talquetamab in people with relapsed or refractory multiple myeloma. Future Oncol. 2023 Sep; 19(27):1823-1840.
Chari A, Askari E, Caers J, Costa LJ, Hilder BW, Krishnan A, Mateos MV, Minnema MC, Oriol A, Pillarisetti K, van de Donk NWCJ, Rodríguez-Otero P. PMID: 37492991.
View in:
PubMed Mentions:
2 Fields:
-
Expert Consensus on the Incorporation of Anti-CD38 Monoclonal Antibody Therapy Into the Management of Newly Diagnosed Multiple Myeloma. Clin Lymphoma Myeloma Leuk. 2023 11; 23(11):815-824.
Lonial S, Bowser AD, Chari A, Costello C, Krishnan A, Usmani SZ. PMID: 37516547.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Teclistamab versus real-world physician's choice of therapy in triple-class exposed relapsed/refractory multiple myeloma. J Comp Eff Res. 2023 06; 12(6):e220186.
Krishnan A, Nooka AK, Chari A, Garfall AL, Martin TG, Nair S, Lin X, Qi K, Londhe A, Pei L, Ammann E, Kobos R, Smit J, Parekh T, Marshall A, Slavcev M, Usmani SZ. PMID: 37114426; PMCID: PMC10402759.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Sequencing T-cell redirection therapies leads to deep and durable responses in patients with relapsed/refractory myeloma. Blood Adv. 2023 03 28; 7(6):1056-1064.
Mouhieddine TH, Van Oekelen O, Melnekoff DT, Li J, Ghodke-Puranik Y, Lancman G, Thibaud S, Pan D, Rajeeve S, Agte S, Aleman A, Sanchez L, Richard S, Rossi A, Richter J, Cho HJ, Rodriguez C, Lagana A, Moshier E, Chari A, Jagannath S, Parekh S. PMID: 36018226; PMCID: PMC10033902.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCTClinical Trials
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Daratumumab, carfilzomib, and dexamethasone in relapsed or refractory myeloma: final analysis of PLEIADES and EQUULEUS. Blood Cancer J. 2023 03 07; 13(1):33.
Moreau P, Chari A, Oriol A, Martinez-Lopez J, Haenel M, Touzeau C, Ailawadhi S, Besemer B, de la Rubia Comos J, Encinas C, Mateos MV, Salwender H, Rodriguez-Otero P, Hulin C, Karlin L, Sureda Balari A, Bargay J, Benboubker L, Rosiñol L, Tarantolo S, Terebelo H, Yang S, Wang J, Nnane I, Qi M, Kosh M, Delioukina M, Goldschmidt H. PMID: 36882409; PMCID: PMC9989580.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Comparative Efficacy of Teclistamab Versus Physician's Choice of Therapy in the Long-term Follow-up of APOLLO, POLLUX, CASTOR, and EQUULEUS Clinical Trials in Patients With Triple-class Exposed Relapsed or Refractory Multiple Myeloma. Clin Lymphoma Myeloma Leuk. 2023 05; 23(5):385-393.
Mateos MV, Chari A, Usmani SZ, Goldschmidt H, Weisel K, Qi K, Londhe A, Nair S, Lin X, Pei L, Ammann E, Kobos R, Smit J, Parekh T, Marshall A, Slavcev M, Moreau P. PMID: 36967244.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCTClinical Trials
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Interventions and outcomes of patients with multiple myeloma receiving salvage therapy after BCMA-directed CAR T therapy. Blood. 2023 02 16; 141(7):756-765.
Van Oekelen O, Nath K, Mouhieddine TH, Farzana T, Aleman A, Melnekoff DT, Ghodke-Puranik Y, Shah GL, Lesokhin A, Giralt S, Thibaud S, Rossi A, Rodriguez C, Sanchez L, Richter J, Richard S, Cho HJ, Chari A, Usmani SZ, Jagannath S, Shah UA, Mailankody S, Parekh S. PMID: 36327160; PMCID: PMC10082354.
View in:
PubMed Mentions:
33 Fields:
Translation:
Humans
-
A phase I study of selinexor combined with weekly carfilzomib and dexamethasone in relapsed/refractory multiple myeloma. Eur J Haematol. 2023 May; 110(5):564-570.
Derman BA, Chari A, Zonder J, Major A, Stefka AT, Jiang K, Karrison T, Jasielec J, Jakubowiak A. PMID: 36726221.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCTClinical Trials
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Corticosteroid tapering is a safe approach in patients with relapsed or refractory multiple myeloma receiving subcutaneous daratumumab: part 3 of the open-label, multicenter, phase 1b PAVO study. Leuk Lymphoma. 2023 02; 64(2):468-472.
Nahi H, Usmani SZ, Mateos MV, van de Donk NWCJ, Oriol A, Plesner T, Bandyopadhyay N, Hellemans P, Tromp B, Nnane I, Zemlickis D, Chari A, Moreau P. PMID: 36593729.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCTClinical Trials
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Talquetamab, a T-Cell-Redirecting GPRC5D Bispecific Antibody for Multiple Myeloma. N Engl J Med. 2022 12 15; 387(24):2232-2244.
Chari A, Minnema MC, Berdeja JG, Oriol A, van de Donk NWCJ, Rodríguez-Otero P, Askari E, Mateos MV, Costa LJ, Caers J, Verona R, Girgis S, Yang S, Goldsmith RB, Yao X, Pillarisetti K, Hilder BW, Russell J, Goldberg JD, Krishnan A. PMID: 36507686.
View in:
PubMed Mentions:
165 Fields:
Translation:
HumansCellsCTClinical Trials
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Rates of Influenza and Pneumococcal Vaccination and Correlation With Survival in Multiple Myeloma Patients. Clin Lymphoma Myeloma Leuk. 2023 03; 23(3):e171-e181.
Thompson MA, Boccadoro M, Leleu X, Vela-Ojeda J, van Rhee F, Weisel KC, Rifkin RM, Usmani SZ, Hájek R, Cook G, Abonour R, Armour M, Morgan KE, Yeh SP, Costello CL, Berdeja JG, Davies FE, Zonder JA, Lee HC, Omel J, Spencer A, Terpos E, Hungria VTM, Puig N, Fu C, Ferrari RH, Ren K, Stull DM, Chari A. PMID: 36641358.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansPHPublic Health
-
Stem Cell Mobilization Yields with Daratumumab- and Lenalidomide-Containing Quadruplet Induction Therapy in Newly Diagnosed Multiple Myeloma: Findings from the MASTER and GRIFFIN Trials. Transplant Cell Ther. 2023 03; 29(3):174.e1-174.e10.
Chhabra S, Callander N, Watts NL, Costa LJ, Thapa B, Kaufman JL, Laubach J, Sborov DW, Reeves B, Rodriguez C, Chari A, Silbermann R, Anderson LD, Bal S, Dhakal B, Nathwani N, Shah N, Medvedova E, Bumma N, Holstein SA, Costello C, Jakubowiak A, Wildes TM, Schmidt T, Orlowski RZ, Shain KH, Cowan AJ, Dholaria B, Cornell RF, Jerkins JH, Pei H, Cortoos A, Patel S, Lin TS, Usmani SZ, Richardson PG, Voorhees PM. PMID: 36494017.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
Trial designs and endpoints for immune therapies in multiple myeloma. Am J Hematol. 2023 03; 98 Suppl 2:S35-S45.
Lancman G, Moshier E, Cho HJ, Parekh S, Richard S, Richter J, Rodriguez C, Rossi A, Sanchez L, Jagannath S, Chari A. PMID: 36200130.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Bridging advanced myeloma patients to subsequent treatments and clinical trials with classical chemotherapy and stem cell support. Bone Marrow Transplant. 2023 01; 58(1):80-86.
Mouhieddine TH, Moshier E, Thibaud S, Puliafito B, Rattu M, Jakubowski R, Sanchez L, Rossi A, Rodriguez C, Richard S, Cho HJ, Parekh S, Chari A, Steinberg A, Richter J. PMID: 36261708.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Duration of frontline therapy and impact on clinical outcomes in newly diagnosed multiple myeloma patients not receiving frontline stem cell transplant. Cancer Med. 2023 02; 12(3):3145-3159.
Ailawadhi S, Ogbonnaya A, Murty S, Cherepanov D, Schroader BK, Romanus D, Farrelly E, Chari A. PMID: 36151787; PMCID: PMC9939178.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Daratumumab plus lenalidomide, bortezomib and dexamethasone in newly diagnosed multiple myeloma: Analysis of vascular thrombotic events in the GRIFFIN study. Br J Haematol. 2022 11; 199(3):355-365.
Sborov DW, Baljevic M, Reeves B, Laubach J, Efebera YA, Rodriguez C, Costa LJ, Chari A, Silbermann R, Holstein SA, Anderson LD, Kaufman JL, Shah N, Pei H, Patel S, Cortoos A, Bartlett JB, Vermeulen J, Lin TS, Voorhees PM, Richardson PG. PMID: 36111391; PMCID: PMC9825872.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCTClinical Trials
-
Ixazomib, lenalidomide and dexamethasone consolidation with randomized ixazomib or lenalidomide maintenance after autologous transplant in newly diagnosed multiple myeloma. Leukemia. 2022 12; 36(12):2917-2921.
Slade M, Martin TG, Nathwani N, Fiala MA, Rettig MP, Gao F, Deol A, Buadi FK, Kaufman JL, Hofmeister CC, Gregory TK, Berdeja J, Chari A, Rosko A, Vij R. PMID: 36114265; PMCID: PMC10445424.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Perspectives on the Risk-Stratified Treatment of Multiple Myeloma. Blood Cancer Discov. 2022 07 06; 3(4):273-284.
Davies FE, Pawlyn C, Usmani SZ, San-Miguel JF, Einsele H, Boyle EM, Corre J, Auclair D, Cho HJ, Lonial S, Sonneveld P, Stewart AK, Bergsagel PL, Kaiser MF, Weisel K, Keats JJ, Mikhael JR, Morgan KE, Ghobrial IM, Orlowski RZ, Landgren CO, Gay F, Caers J, Chng WJ, Chari A, Walker BA, Kumar SK, Costa LJ, Anderson KC, Morgan GJ. PMID: 35653112; PMCID: PMC9894570.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Teclistamab in Relapsed or Refractory Multiple Myeloma. N Engl J Med. 2022 08 11; 387(6):495-505.
Moreau P, Garfall AL, van de Donk NWCJ, Nahi H, San-Miguel JF, Oriol A, Nooka AK, Martin T, Rosinol L, Chari A, Karlin L, Benboubker L, Mateos MV, Bahlis N, Popat R, Besemer B, Martínez-López J, Sidana S, Delforge M, Pei L, Trancucci D, Verona R, Girgis S, Lin SXW, Olyslager Y, Jaffe M, Uhlar C, Stephenson T, Van Rampelbergh R, Banerjee A, Goldberg JD, Kobos R, Krishnan A, Usmani SZ. PMID: 35661166; PMCID: PMC10587778.
View in:
PubMed Mentions:
279 Fields:
Translation:
HumansCellsCTClinical Trials
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A Three-Gene Signature Predicts Response to Selinexor in Multiple Myeloma. JCO Precis Oncol. 2022 06; 6:e2200147.
Restrepo P, Bhalla S, Ghodke-Puranik Y, Aleman A, Leshchenko V, Melnekoff DT, Agte S, Jiang J, Madduri D, Richter J, Richard S, Chari A, Cho HJ, Jagannath S, Walker CJ, Landesman Y, Laganà A, Parekh S. PMID: 35704796; PMCID: PMC10530420.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Daratumumab plus lenalidomide/bortezomib/dexamethasone in Black patients with transplant-eligible newly diagnosed multiple myeloma in GRIFFIN. Blood Cancer J. 2022 04 13; 12(4):63.
Nooka AK, Kaufman JL, Rodriguez C, Jakubowiak A, Efebera Y, Reeves B, Wildes T, Holstein SA, Anderson LD, Badros A, Shune L, Chari A, Pei H, Cortoos A, Patel S, Bartlett JB, Vermeulen J, Lin TS, Richardson PG, Voorhees P. PMID: 35418120; PMCID: PMC9007985.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Preferences and Priorities for Relapsed Multiple Myeloma Treatments Among Patients and Caregivers in the United States. Patient Prefer Adherence. 2022; 16:573-585.
Auclair D, Mansfield C, Fiala MA, Chari A, Cole CE, Kaufman JL, Orloff GJ, Siegel DS, Zonder JA, Mange B, Yesil J, Dalal M, Mikhael JR. PMID: 35256844; PMCID: PMC8898176.
View in:
PubMed Mentions:
4
-
Consensus guidelines and recommendations for infection prevention in multiple myeloma: a report from the International Myeloma Working Group. Lancet Haematol. 2022 Feb; 9(2):e143-e161.
Raje NS, Anaissie E, Kumar SK, Lonial S, Martin T, Gertz MA, Krishnan A, Hari P, Ludwig H, O'Donnell E, Yee A, Kaufman JL, Cohen AD, Garderet L, Wechalekar AF, Terpos E, Khatry N, Niesvizky R, Yi Q, Joshua DE, Saikia T, Leung N, Engelhardt M, Mothy M, Branagan A, Chari A, Reiman AJ, Lipe B, Richter J, Rajkumar SV, Miguel JS, Anderson KC, Stadtmauer EA, Prabhala RH, McCarthy PL, Munshi NC. PMID: 35114152.
View in:
PubMed Mentions:
54 Fields:
Translation:
Humans
-
Filanesib plus bortezomib and dexamethasone in relapsed/refractory t(11;14) and 1q21 gain multiple myeloma. Cancer Med. 2022 01; 11(2):358-370.
Pan D, Kaufman JL, Htut M, Agrawal M, Mazumder A, Cornell RF, Zonder JA, Fay JW, Modiano MR, Moshier EL, Rush SA, Tunquist BJ, Chari A. PMID: 34921527; PMCID: PMC8729045.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCellsCTClinical Trials
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Patient similarity network of newly diagnosed multiple myeloma identifies patient subgroups with distinct genetic features and clinical implications. Sci Adv. 2021 Nov 19; 7(47):eabg9551.
Bhalla S, Melnekoff DT, Aleman A, Leshchenko V, Restrepo P, Keats J, Onel K, Sawyer JR, Madduri D, Richter J, Richard S, Chari A, Cho HJ, Dudley JT, Jagannath S, Laganà A, Parekh S. PMID: 34788103; PMCID: PMC8598000.
View in:
PubMed Mentions:
19 Fields:
-
The Safety and Efficacy of Radiation Therapy with Concurrent Dexamethasone, Cyclophosphamide, Etoposide, and Cisplatin-Based Systemic Therapy for Multiple Myeloma. Clin Lymphoma Myeloma Leuk. 2022 03; 22(3):192-197.
Nehlsen AD, Sindhu KK, Moshier E, Richter J, Richard S, Chari A, Sanchez L, Parekh S, Cho HJ, Jagannath S, Dharmarajan K. PMID: 34736880; PMCID: PMC9040190.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
A combination of carfilzomib, dexamethasone, and daratumumab for treatment of adult patients with relapsed/refractory multiple myeloma in two dosing regimens: once-weekly and twice-weekly. Expert Rev Hematol. 2021 12; 14(12):1049-1058.
Leleu X, Chari A, Richard S, Khurana M, Yusuf A, Usmani SZ. PMID: 34546844.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
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Treatment Bridging With a 28-Day Metronomic Therapy (Metro-28) for Relapsed Refractory Multiple Myeloma. Clin Lymphoma Myeloma Leuk. 2022 02; 22(2):129-132.
Mouhieddine TH, Hieulle J, Moshier E, Richard S, Richter J, Cho HJ, Parekh S, Barlogie B, Chari A, Jagannath S, Madduri D. PMID: 34670732.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Bispecific Antibodies in Multiple Myeloma: Present and Future. Blood Cancer Discov. 2021 Sep; 2(5):423-433.
Lancman G, Sastow DL, Cho HJ, Jagannath S, Madduri D, Parekh SS, Richard S, Richter J, Sanchez L, Chari A. PMID: 34661161; PMCID: PMC8510808.
View in:
PubMed Mentions:
39 Fields:
Translation:
HumansCells
-
Teclistamab, a B-cell maturation antigen × CD3 bispecific antibody, in patients with relapsed or refractory multiple myeloma (MajesTEC-1): a multicentre, open-label, single-arm, phase 1 study. Lancet. 2021 08 21; 398(10301):665-674.
Usmani SZ, Garfall AL, van de Donk NWCJ, Nahi H, San-Miguel JF, Oriol A, Rosinol L, Chari A, Bhutani M, Karlin L, Benboubker L, Pei L, Verona R, Girgis S, Stephenson T, Elsayed Y, Infante J, Goldberg JD, Banerjee A, Mateos MV, Krishnan A. PMID: 34388396.
View in:
PubMed Mentions:
114 Fields:
Translation:
HumansCellsCTClinical Trials
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Longer term outcomes with single-agent belantamab mafodotin in patients with relapsed or refractory multiple myeloma: 13-month follow-up from the pivotal DREAMM-2 study. Cancer. 2021 11 15; 127(22):4198-4212.
Lonial S, Lee HC, Badros A, Trudel S, Nooka AK, Chari A, Abdallah AO, Callander N, Sborov D, Suvannasankha A, Weisel K, Voorhees PM, Womersley L, Baron J, Piontek T, Lewis E, Opalinska J, Gupta I, Cohen AD. PMID: 34314018; PMCID: PMC8597112.
View in:
PubMed Mentions:
59 Fields:
Translation:
Humans
-
Selinexor for the treatment of patients with previously treated multiple myeloma. Expert Rev Hematol. 2021 08; 14(8):697-706.
Mo CC, Jagannath S, Chari A, Nooka AK, Lonial S, Siegel D, Biran N, Gasparetto C, Bahlis NJ, Richardson P. PMID: 33985401.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Optimal Supportive Care With Selinexor Improves Outcomes in Patients With Relapsed/Refractory Multiple Myeloma. Clin Lymphoma Myeloma Leuk. 2021 12; 21(12):e975-e984.
Chari A, Florendo E, Mancia IS, Cho H, Madduri D, Parekh S, Richter J, Dhadwal A, Thomas J, Jiang G, Lagana A, Bhalla S, Jagannath S. PMID: 34404623.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCTClinical Trials
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Selinexor, bortezomib, and dexamethasone versus bortezomib and dexamethasone in previously treated multiple myeloma: Outcomes by cytogenetic risk. Am J Hematol. 2021 09 01; 96(9):1120-1130.
Richard S, Chari A, Delimpasi S, Simonova M, Spicka I, Pour L, Kriachok I, Dimopoulos MA, Pylypenko H, Auner HW, Leleu X, Usenko G, Hajek R, Benjamin R, Dolai TK, Sinha DK, Venner CP, Garg M, Stevens DA, Quach H, Jagannath S, Moreau P, Levy M, Badros A, Anderson LD, Bahlis NJ, Facon T, Mateos MV, Cavo M, Chang H, Landesman Y, Chai Y, Arazy M, Shah J, Shacham S, Kauffman MG, Grosicki S, Richardson PG. PMID: 34062004; PMCID: PMC8457116.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCTClinical Trials
-
Highly variable SARS-CoV-2 spike antibody responses to two doses of COVID-19 RNA vaccination in patients with multiple myeloma. Cancer Cell. 2021 08 09; 39(8):1028-1030.
Van Oekelen O, Gleason CR, Agte S, Srivastava K, Beach KF, Aleman A, Kappes K, PVI/Seronet team, Mouhieddine TH, Wang B, Chari A, Cordon-Cardo C, Krammer F, Jagannath S, Simon V, Wajnberg A, Parekh S. PMID: 34242572; PMCID: PMC8238657.
View in:
PubMed Mentions:
118 Fields:
Translation:
HumansCellsPHPublic Health
-
Panobinostat From Bench to Bedside: Rethinking the Treatment Paradigm for Multiple Myeloma. Clin Lymphoma Myeloma Leuk. 2021 11; 21(11):752-765.
Berdeja JG, Laubach JP, Richter J, Stricker S, Spencer A, Richardson PG, Chari A. PMID: 34340951.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Daratumumab Plus Carfilzomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma. Clin Lymphoma Myeloma Leuk. 2021 10; 21(10):701-710.
Jakubowiak A, Usmani SZ, Krishnan A, Lonial S, Comenzo RL, Wang J, de Boer C, Deraedt W, Weiss BM, Schecter JM, Chari A. PMID: 34274290.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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Subcutaneous daratumumab in patients with relapsed or refractory multiple myeloma: Part 2 of the open-label, multicenter, dose-escalation phase 1b study (PAVO). Haematologica. 2021 06 01; 106(6):1725-1732.
San-Miguel J, Usmani SZ, Mateos MV, van de Donk NWCJ, Kaufman JL, Moreau P, Oriol A, Plesner T, Benboubker L, Liu K, Hellemans P, Masterson T, Clemens PL, Luo M, Farnsworth A, Nahi H, Chari A. PMID: 32354874; PMCID: PMC8168515.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCTClinical Trials
-
Real-world comparative effectiveness of triplets containing bortezomib (B), carfilzomib (C), daratumumab (D), or ixazomib (I) in relapsed/refractory multiple myeloma (RRMM) in the US. Ann Hematol. 2021 Sep; 100(9):2325-2337.
Davies F, Rifkin R, Costello C, Morgan G, Usmani S, Abonour R, Palumbo A, Romanus D, Hajek R, Terpos E, Cherepanov D, Stull DM, Huang H, Leleu X, Berdeja J, Lee HC, Weisel K, Thompson M, Boccadoro M, Zonder J, Cook G, Puig N, Vela-Ojeda J, Farrelly E, Raju A, Blazer M, Chari A. PMID: 33970288; PMCID: PMC8357697.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Ixazomib-lenalidomide-dexamethasone in routine clinical practice: effectiveness in relapsed/refractory multiple myeloma. Future Oncol. 2021 Jul; 17(19):2499-2512.
Hájek R, Minarík J, Straub J, Pour L, Jungova A, Berdeja JG, Boccadoro M, Brozova L, Spencer A, van Rhee F, Vela-Ojeda J, Thompson MA, Abonour R, Chari A, Cook G, Costello CL, Davies FE, Hungria VT, Lee HC, Leleu X, Puig N, Rifkin RM, Terpos E, Usmani SZ, Weisel KC, Zonder JA, Barinová M, Kuhn M, Šilar J, Cápková L, Galvez K, Lu J, Elliott J, Stull DM, Ren K, Maisnar V. PMID: 33769076.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Phase 1b trial of isatuximab, an anti-CD38 monoclonal antibody, in combination with carfilzomib as treatment of relapsed/refractory multiple myeloma. Cancer. 2021 06 01; 127(11):1816-1826.
Martin TG, Shah N, Richter J, Vesole DH, Wong SW, Huang CY, Madduri D, Jagannath S, Siegel DS, Biran N, Wolf JL, Parekh S, Cho HJ, Munster P, Richard S, Ziti-Ljajic S, Chari A. PMID: 33735504; PMCID: PMC8252002.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCTClinical Trials
-
Management of patients with multiple myeloma beyond the clinical-trial setting: understanding the balance between efficacy, safety and tolerability, and quality of life. Blood Cancer J. 2021 02 18; 11(2):40.
Terpos E, Mikhael J, Hajek R, Chari A, Zweegman S, Lee HC, Mateos MV, Larocca A, Ramasamy K, Kaiser M, Cook G, Weisel KC, Costello CL, Elliott J, Palumbo A, Usmani SZ. PMID: 33602913; PMCID: PMC7891472.
View in:
PubMed Mentions:
38 Fields:
Translation:
Humans
-
Efficacy of Intravenous Immunoglobulin for Preventing Infections in Patients with Multiple Myeloma. Clin Lymphoma Myeloma Leuk. 2021 05; 21(5):e470-e476.
Lancman G, Lozada K, Athar N, Jacobs S, Doucette J, Cho HJ, Jagannath S, Madduri D, Parekh S, Richard S, Richter J, Chari A. PMID: 33716054.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Subcutaneous daratumumab and hyaluronidase-fihj in newly diagnosed or relapsed/refractory multiple myeloma. Ther Adv Hematol. 2021; 12:2040620720987075.
Sanchez L, Richter J, Cho HJ, Jagannath S, Madduri D, Parekh S, Richard S, Tam L, Verina D, Chari A. PMID: 33613930; PMCID: PMC7841854.
View in:
PubMed Mentions:
4
-
Evaluation of Cardiac Repolarization in the Randomized Phase 2 Study of Intermediate- or High-Risk Smoldering Multiple Myeloma Patients Treated with Daratumumab Monotherapy. Adv Ther. 2021 02; 38(2):1328-1341.
Chari A, Munder M, Weisel K, Jenner M, Bygrave C, Petrucci MT, Boccadoro M, Cavo M, van de Donk NWCJ, Turgut M, Demirkan F, Karadogan I, Libby E, Kleiman R, Kuppens S, Bandekar R, Neff T, Heuck C, Qi M, Clemens PL, Goldschmidt H. PMID: 33474705; PMCID: PMC7889563.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCTClinical Trials
-
Clinical features associated with COVID-19 outcome in multiple myeloma: first results from the International Myeloma Society data set. Blood. 2020 12 24; 136(26):3033-3040.
Chari A, Samur MK, Martinez-Lopez J, Cook G, Biran N, Yong K, Hungria V, Engelhardt M, Gay F, García Feria A, Oliva S, Oostvogels R, Gozzetti A, Rosenbaum C, Kumar S, Stadtmauer EA, Einsele H, Beksac M, Weisel K, Anderson KC, Mateos MV, Moreau P, San-Miguel J, Munshi NC, Avet-Loiseau H. PMID: 33367546; PMCID: PMC7759145.
View in:
PubMed Mentions:
102 Fields:
Translation:
HumansCells
-
A comprehensive overview of daratumumab and carfilzomib and the recently approved daratumumab, carfilzomib and dexamethasone regimen in relapsed/refractory multiple myeloma. Expert Rev Hematol. 2021 01; 14(1):31-45.
Richard S, Jagannath S, Cho HJ, Parekh S, Madduri D, Richter J, Chari A. PMID: 33331794.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
-
Health-Related Quality of Life in Transplant-Ineligible Patients With Newly Diagnosed Multiple Myeloma: Findings From the Phase III MAIA Trial. J Clin Oncol. 2021 01 20; 39(3):227-237.
Perrot A, Facon T, Plesner T, Usmani SZ, Kumar S, Bahlis NJ, Hulin C, Orlowski RZ, Nahi H, Mollee P, Ramasamy K, Roussel M, Jaccard A, Delforge M, Karlin L, Arnulf B, Chari A, He J, Ho KF, Van Rampelbergh R, Uhlar CM, Wang J, Kobos R, Gries KS, Fastenau J, Weisel K. PMID: 33326255; PMCID: PMC8078427.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCTClinical Trials
-
Efficacy and safety of oral panobinostat plus subcutaneous bortezomib and oral dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma (PANORAMA 3): an open-label, randomised, phase 2 study. Lancet Oncol. 2021 01; 22(1):142-154.
Laubach JP, Schjesvold F, Mariz M, Dimopoulos MA, Lech-Maranda E, Spicka I, Hungria VTM, Shelekhova T, Abdo A, Jacobasch L, Polprasert C, Hájek R, Illés Á, Wróbel T, Sureda A, Beksac M, Gonçalves IZ, Bladé J, Rajkumar SV, Chari A, Lonial S, Spencer A, Maison-Blanche P, Moreau P, San-Miguel JF, Richardson PG. PMID: 33301738.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCTClinical Trials
-
Bispecifics, trispecifics, and other novel immune treatments in myeloma. Hematology Am Soc Hematol Educ Program. 2020 12 04; 2020(1):264-271.
Lancman G, Richter J, Chari A. PMID: 33275733; PMCID: PMC7727546.
View in:
PubMed Mentions:
28 Fields:
Translation:
Humans
-
Real-world treatment patterns, healthcare use and costs in triple-class exposed relapsed and refractory multiple myeloma patients in the USA. Future Oncol. 2021 Feb; 17(5):503-515.
Madduri D, Hagiwara M, Parikh K, Pelletier C, Delea TE, Kee A, Chari A. PMID: 33522834.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Targeting Nuclear Export Proteins in Multiple Myeloma Therapy. Target Oncol. 2020 12; 15(6):697-708.
Theodoropoulos N, Lancman G, Chari A. PMID: 33074469; PMCID: PMC7570401.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Overall survival with oral selinexor plus low-dose dexamethasone versus real-world therapy in triple-class-refractory multiple myeloma. EJHaem. 2021 Feb; 2(1):48-55.
Richardson PG, Jagannath S, Chari A, Vogl DT, Dimopoulos MA, Moreau P, Dingli D, Wei LJ, Richter J, Biran N, Siegel D, Reichmann W, Li L, Tang S, Saint-Martin JR, Joshi A, Kauffman M, Shah J, Shacham S, Lonial S. PMID: 35846096; PMCID: PMC9175889.
View in:
PubMed Mentions:
5
-
Correction: COVID-19 Infections and Outcomes in Patients with Multiple Myeloma in New York City: A Cohort Study from Five Academic Centers. Blood Cancer Discov. 2020 11; 1(3):290.
Hultcrantz M, Richter J, Rosenbaum CA, Patel D, Smith EL, Korde N, Lu SX, Mailankody S, Shah UA, Lesokhin AM, Hassoun H, Tan C, Maura F, Derkach A, Diamond B, Rossi A, Pearse R, Madduri D, Chari A, Kaminetzky D, Braunstein MJ, Gordillo C, Reshef R, Taur Y, Davies FE, Jagannath S, Niesvizky R, Lentzsch S, Morgan GJ, Landgren O. PMID: 34661147; PMCID: PMC8510790.
View in:
PubMed Mentions:
14 Fields:
-
Exposure-Response and Population Pharmacokinetic Analyses of a Novel Subcutaneous Formulation of Daratumumab Administered to Multiple Myeloma Patients. J Clin Pharmacol. 2021 05; 61(5):614-627.
Luo MM, Usmani SZ, Mateos MV, Nahi H, Chari A, San-Miguel J, Touzeau C, Suzuki K, Kaiser M, Carson R, Heuck C, Qi M, Zhou H, Sun YN, Parasrampuria DA. PMID: 33145788; PMCID: PMC8048619.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Daratumumab, lenalidomide, and dexamethasone in relapsed/refractory myeloma: a cytogenetic subgroup analysis of POLLUX. Blood Cancer J. 2020 11 03; 10(11):111.
Kaufman JL, Dimopoulos MA, White D, Benboubker L, Cook G, Leiba M, Morton J, Joy Ho P, Kim K, Takezako N, Moreau P, Sutherland HJ, Magen H, Iida S, Kim JS, Miles Prince H, Cochrane T, Oriol A, Bahlis NJ, Chari A, O'Rourke L, Trivedi S, Casneuf T, Krevvata M, Ukropec J, Kobos R, Avet-Loiseau H, Usmani SZ, San-Miguel J. PMID: 33149130; PMCID: PMC7643179.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCellsCTClinical Trials
-
Efficacy and safety of weekly carfilzomib (70 mg/m2), dexamethasone, and daratumumab (KdD70) is comparable to twice-weekly KdD56 while being a more convenient dosing option: a cross-study comparison of the CANDOR and EQUULEUS studies. Leuk Lymphoma. 2021 02; 62(2):358-367.
Leleu X, Beksac M, Chou T, Dimopoulos M, Yoon SS, Prince HM, Pour L, Shelekhova T, Chari A, Khurana M, Zhang J, Obreja M, Qi M, Oriol A, Siegel D. PMID: 33112184.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Overall survival of patients with triple-class refractory multiple myeloma treated with selinexor plus dexamethasone vs standard of care in MAMMOTH. Am J Hematol. 2021 01; 96(1):E5-E8.
Cornell R, Hari P, Tang S, Biran N, Callander N, Chari A, Chhabra S, Fiala MA, Gahvari Z, Gandhi U, Godby K, Gupta R, Jagannath S, Jagosky M, Kang Y, Kansagra A, Kauffman M, Kodali S, Kumar SK, Lakshman A, Liedtke M, Lonial S, Ma X, Malek E, Mansour J, McGehee EF, Neppalli A, Paul B, Richardson P, Scott EC, Shacham S, Shah J, Siegel DS, Umyarova E, Usmani SZ, Varnado W, Vij R, Costa L. PMID: 32974944.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCTClinical Trials
-
Selinexor, bortezomib, and dexamethasone (SVD) in heavily treated relapsed refractory multiple myeloma. Ann Hematol. 2021 Dec; 100(12):3057-3060.
Mouhieddine TH, Parekh S, Cho HJ, Richter J, DeCastro A, Shah J, Landesman Y, Chari A, Jagannath S, Madduri D. PMID: 33009581.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Immunomodulatory drug- and proteasome inhibitor-backbone regimens in the treatment of relapsed multiple myeloma: an evidence-based review. Expert Rev Hematol. 2020 09; 13(9):943-958.
Sanchez L, Barley K, Richter J, Franz J, Cho HJ, Jagannath S, Madduri D, Parekh S, Richard S, Chari A. PMID: 32731770.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Daratumumab, lenalidomide, bortezomib, and dexamethasone for transplant-eligible newly diagnosed multiple myeloma: the GRIFFIN trial. Blood. 2020 08 20; 136(8):936-945.
Voorhees PM, Kaufman JL, Laubach J, Sborov DW, Reeves B, Rodriguez C, Chari A, Silbermann R, Costa LJ, Anderson LD, Nathwani N, Shah N, Efebera YA, Holstein SA, Costello C, Jakubowiak A, Wildes TM, Orlowski RZ, Shain KH, Cowan AJ, Murphy S, Lutska Y, Pei H, Ukropec J, Vermeulen J, de Boer C, Hoehn D, Lin TS, Richardson PG. PMID: 32325490; PMCID: PMC7441167.
View in:
PubMed Mentions:
279 Fields:
Translation:
HumansCTClinical Trials
-
A phase II study of pomalidomide, daily oral cyclophosphamide, and dexamethasone in relapsed/refractory multiple myeloma. Leuk Lymphoma. 2020 09; 61(9):2208-2215.
Van Oekelen O, Parekh S, Cho HJ, Vishnuvardhan N, Madduri D, Richter J, Ip C, Lau K, Florendo E, Mancia IS, Thomas J, Verina D, Chan E, Zarychta K, La L, Strumolo G, Melnekoff DT, Leshchenko VV, Kim-Schulze S, Couto S, Wang M, Pierceall WE, Thakurta A, Laganà A, Jagannath S, Chari A. PMID: 32812822.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCTClinical Trials
-
Subcutaneous daratumumab plus standard treatment regimens in patients with multiple myeloma across lines of therapy (PLEIADES): an open-label Phase II study. Br J Haematol. 2021 03; 192(5):869-878.
Chari A, Rodriguez-Otero P, McCarthy H, Suzuki K, Hungria V, Sureda Balari A, Perrot A, Hulin C, Magen H, Iida S, Maisnar V, Karlin L, Pour L, Parasrampuria DA, Masterson T, Kosh M, Yang S, Delioukina M, Qi M, Carson R, Touzeau C. PMID: 33216361.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
-
COVID-19 Infections and Clinical Outcomes in Patients with Multiple Myeloma in New York City: A Cohort Study from Five Academic Centers. Blood Cancer Discov. 2020 11; 1(3):234-243.
Hultcrantz M, Richter J, Rosenbaum CA, Patel D, Smith EL, Korde N, Lu SX, Mailankody S, Shah UA, Lesokhin AM, Hassoun H, Tan C, Maura F, Derkach A, Diamond B, Rossi A, Pearse RN, Madduri D, Chari A, Kaminetzky D, Braunstein MJ, Gordillo C, Reshef R, Taur Y, Davies FE, Jagannath S, Niesvizky R, Lentzsch S, Morgan GJ, Landgren O. PMID: 34651141; PMCID: PMC7668224.
View in:
PubMed Mentions:
34 Fields:
-
A tertiary center experience of multiple myeloma patients with COVID-19: lessons learned and the path forward. J Hematol Oncol. 2020 07 14; 13(1):94.
Wang B, Van Oekelen O, Mouhieddine TH, Del Valle DM, Richter J, Cho HJ, Richard S, Chari A, Gnjatic S, Merad M, Jagannath S, Parekh S, Madduri D. PMID: 32664919; PMCID: PMC7359431.
View in:
PubMed Mentions:
88 Fields:
Translation:
HumansCellsPHPublic Health
-
The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of multiple myeloma. J Immunother Cancer. 2020 07; 8(2).
Shah N, Aiello J, Avigan DE, Berdeja JG, Borrello IM, Chari A, Cohen AD, Ganapathi K, Gray L, Green D, Krishnan A, Lin Y, Manasanch E, Munshi NC, Nooka AK, Rapoport AP, Smith EL, Vij R, Dhodapkar M. PMID: 32661116; PMCID: PMC7359060.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCTClinical Trials
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A tertiary center experience of multiple myeloma patients with COVID-19: lessons learned and the path forward. medRxiv. 2020 Jun 29.
Wang B, Van Oekelen O, Mouhieddine TH, Del Valle DM, Richter J, Cho HJ, Richard S, Chari A, Gnjatic S, Merad M, Jagannath S, Parekh S, Madduri D. PMID: 32577702; PMCID: PMC7302311.
View in:
PubMed Mentions:
-
COVID-19 infections and outcomes in patients with multiple myeloma in New York City: a cohort study from five academic centers. medRxiv. 2020 Jun 11.
Hultcrantz M, Richter J, Rosenbaum C, Patel D, Smith E, Korde N, Lu S, Mailankody S, Shah U, Lesokhin A, Hassoun H, Tan C, Maura F, Derkacs A, Diamond B, Rossi A, Pearse RN, Madduri D, Chari A, Kaminetsky D, Braunstein M, Gordillo C, Davies F, Jagannath S, Niesvizky R, Lentzsch S, Morgan G, Landgren O. PMID: 32577667; PMCID: PMC7302217.
View in:
PubMed Mentions:
-
Selinexor in relapsed/refractory multiple myeloma. Ther Adv Hematol. 2020; 11:2040620720930629.
Richter J, Madduri D, Richard S, Chari A. PMID: 32566115; PMCID: PMC7285937.
View in:
PubMed Mentions:
15
-
Timing of Autologous Stem Cell Transplantation for Multiple Myeloma in the Era of Current Therapies. Clin Lymphoma Myeloma Leuk. 2020 10; 20(10):e734-e751.
Leng S, Moshier E, Tremblay D, Hu L, Biran N, Barman N, Parekh S, Cho H, Madduri D, Richter J, Barlogie B, Jagannath S, Chari A. PMID: 32660906.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Myeloma CAR-T CRS Management With IL-1R Antagonist Anakinra. Clin Lymphoma Myeloma Leuk. 2020 09; 20(9):632-636.e1.
Jatiani SS, Aleman A, Madduri D, Chari A, Cho HJ, Richard S, Richter J, Brody J, Jagannath S, Parekh S. PMID: 32553791; PMCID: PMC7484011.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
-
Final analysis of a phase 1/2b study of ibrutinib combined with carfilzomib/dexamethasone in patients with relapsed/refractory multiple myeloma. Hematol Oncol. 2020 Aug; 38(3):353-362.
Chari A, Cornell RF, Gasparetto C, Karanes C, Matous JV, Niesvizky R, Lunning M, Usmani SZ, Anderson LD, Chhabra S, Girnius S, Shustik C, Stuart R, Lee Y, Salman Z, Liu E, Valent J. PMID: 32053229; PMCID: PMC7496325.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCTClinical Trials
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Real-world outcomes and factors impacting treatment choice in relapsed and/or refractory multiple myeloma (RRMM): a comparison of VRd, KRd, and IRd. Expert Rev Hematol. 2020 04; 13(4):421-433.
Chari A, Richardson PG, Romanus D, Dimopoulos MA, Sonneveld P, Terpos E, Hajek R, Raju A, Palumbo A, Cain LE, Blazer M, Huang H, Farrelly E, Ailawadhi S. PMID: 32148109.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
-
Consensus Recommendations for the Clinical Management of Patients With Multiple Myeloma Treated With Selinexor. Clin Lymphoma Myeloma Leuk. 2020 06; 20(6):351-357.
Mikhael J, Noonan KR, Faiman B, Gleason C, Nooka AK, Costa LJ, Jagannath S, Richardson PG, Siegel D, Chari A, Lentzch S. PMID: 32245742.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
Selinexor-based regimens for the treatment of myeloma refractory to chimeric antigen receptor T cell therapy. Br J Haematol. 2020 05; 189(4):e126-e130.
Chari A, Vogl DT, Jagannath S, Jasielec J, Unger TJ, DeCastro A, Shah J, Kauffman M, Shacham S, Jakubowiak A. PMID: 32124443.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Integrated safety profile of selinexor in multiple myeloma: experience from 437 patients enrolled in clinical trials. Leukemia. 2020 09; 34(9):2430-2440.
Gavriatopoulou M, Chari A, Chen C, Bahlis N, Vogl DT, Jakubowiak A, Dingli D, Cornell RF, Hofmeister CC, Siegel D, Berdeja JG, Reece D, White D, Lentzsch S, Gasparetto C, Huff CA, Jagannath S, Baz R, Nooka AK, Richter J, Abonour R, Parker TL, Yee AJ, Moreau P, Lonial S, Tuchman S, Weisel KC, Mohty M, Choquet S, Unger TJ, Li K, Chai Y, Li L, Shah J, Shacham S, Kauffman MG, Dimopoulos MA. PMID: 32094461; PMCID: PMC7449872.
View in:
PubMed Mentions:
30 Fields:
Translation:
Humans
-
MAGE-A inhibit apoptosis and promote proliferation in multiple myeloma through regulation of BIM and p21Cip1. Oncotarget. 2020 Feb 18; 11(7):727-739.
Mei AH, Tung K, Han J, Perumal D, Laganà A, Keats J, Auclair D, Chari A, Jagannath S, Parekh S, Cho HJ. PMID: 32133047; PMCID: PMC7041939.
View in:
PubMed Mentions:
12 Fields:
-
B-cell maturation antigen (BCMA) in multiple myeloma: rationale for targeting and current therapeutic approaches. Leukemia. 2020 04; 34(4):985-1005.
Shah N, Chari A, Scott E, Mezzi K, Usmani SZ. PMID: 32055000; PMCID: PMC7214244.
View in:
PubMed Mentions:
183 Fields:
Translation:
HumansCells
-
Daratumumab monotherapy for patients with intermediate-risk or high-risk smoldering multiple myeloma: a randomized, open-label, multicenter, phase 2 study (CENTAURUS). Leukemia. 2020 07; 34(7):1840-1852.
Landgren CO, Chari A, Cohen YC, Spencer A, Voorhees P, Estell JA, Sandhu I, Jenner MW, Williams C, Cavo M, van de Donk NWCJ, Beksac M, Moreau P, Goldschmidt H, Kuppens S, Bandekar R, Clemens PL, Neff T, Heuck C, Qi M, Hofmeister CC. PMID: 32024950; PMCID: PMC7326703.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCTClinical Trials
-
Selinexor for the treatment of multiple myeloma. Expert Opin Pharmacother. 2020 Mar; 21(4):399-408.
Podar K, Shah J, Chari A, Richardson PG, Jagannath S. PMID: 31957504.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
-
Recapturing disease response: A phase 2 study of carfilzomib 56 mg/m2 in patients with relapsed or refractory multiple myeloma who have progressed on carfilzomib 27 mg/m2. Am J Hematol. 2020 02; 95(2):E51-E54.
Barley K, Sanchez L, Cho HJ, Parekh S, Madduri D, Richter J, Isola L, Goldstein T, Dhadwal A, Zarychta K, Sanchez GM, Catamero D, Verina D, Florendo E, Yum MH, La L, Gullie J, Chan E, Jagannath S, Chari A. PMID: 31814152.
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PubMed Mentions: Fields:
Translation:
HumansCTClinical Trials
-
Mutation-derived Neoantigen-specific T-cell Responses in Multiple Myeloma. Clin Cancer Res. 2020 01 15; 26(2):450-464.
Perumal D, Imai N, Laganà A, Finnigan J, Melnekoff D, Leshchenko VV, Solovyov A, Madduri D, Chari A, Cho HJ, Dudley JT, Brody JD, Jagannath S, Greenbaum B, Gnjatic S, Bhardwaj N, Parekh S. PMID: 31857430; PMCID: PMC6980765.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansCells
-
Belantamab mafodotin for relapsed or refractory multiple myeloma (DREAMM-2): a two-arm, randomised, open-label, phase 2 study. Lancet Oncol. 2020 02; 21(2):207-221.
Lonial S, Lee HC, Badros A, Trudel S, Nooka AK, Chari A, Abdallah AO, Callander N, Lendvai N, Sborov D, Suvannasankha A, Weisel K, Karlin L, Libby E, Arnulf B, Facon T, Hulin C, Kortüm KM, Rodríguez-Otero P, Usmani SZ, Hari P, Baz R, Quach H, Moreau P, Voorhees PM, Gupta I, Hoos A, Zhi E, Baron J, Piontek T, Lewis E, Jewell RC, Dettman EJ, Popat R, Esposti SD, Opalinska J, Richardson P, Cohen AD. PMID: 31859245.
View in:
PubMed Mentions:
329 Fields:
Translation:
HumansCTClinical Trials
-
Selinexor for Refractory Multiple Myeloma. Reply. N Engl J Med. 2019 11 14; 381(20):1977-1978.
Chari A, Vogl DT, Jagannath S. PMID: 31722163.
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PubMed Mentions: Fields:
Translation:
Humans
-
Randomized Clinical Trial Representativeness and Outcomes in Real-World Patients: Comparison of 6 Hallmark Randomized Clinical Trials of Relapsed/Refractory Multiple Myeloma. Clin Lymphoma Myeloma Leuk. 2020 01; 20(1):8-17.e16.
Chari A, Romanus D, Palumbo A, Blazer M, Farrelly E, Raju A, Huang H, Richardson P. PMID: 31722839.
View in:
PubMed Mentions:
46 Fields:
Translation:
Humans
-
Oral Selinexor-Dexamethasone for Triple-Class Refractory Multiple Myeloma. N Engl J Med. 2019 08 22; 381(8):727-738.
Chari A, Vogl DT, Gavriatopoulou M, Nooka AK, Yee AJ, Huff CA, Moreau P, Dingli D, Cole C, Lonial S, Dimopoulos M, Stewart AK, Richter J, Vij R, Tuchman S, Raab MS, Weisel KC, Delforge M, Cornell RF, Kaminetzky D, Hoffman JE, Costa LJ, Parker TL, Levy M, Schreder M, Meuleman N, Frenzel L, Mohty M, Choquet S, Schiller G, Comenzo RL, Engelhardt M, Illmer T, Vlummens P, Doyen C, Facon T, Karlin L, Perrot A, Podar K, Kauffman MG, Shacham S, Li L, Tang S, Picklesimer C, Saint-Martin JR, Crochiere M, Chang H, Parekh S, Landesman Y, Shah J, Richardson PG, Jagannath S. PMID: 31433920.
View in:
PubMed Mentions:
260 Fields:
Translation:
HumansCTClinical Trials
-
Patient-Reported Factors in Treatment Satisfaction in Patients with Relapsed/Refractory Multiple Myeloma (RRMM). Oncologist. 2019 11; 24(11):1479-1487.
Chari A, Romanus D, DasMahapatra P, Hoole M, Lowe M, Curran C, Campbell S, Bell JA. PMID: 31371520; PMCID: PMC6853123.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Subcutaneous delivery of daratumumab in relapsed or refractory multiple myeloma. Blood. 2019 08 22; 134(8):668-677.
Usmani SZ, Nahi H, Mateos MV, van de Donk NWCJ, Chari A, Kaufman JL, Moreau P, Oriol A, Plesner T, Benboubker L, Hellemans P, Masterson T, Clemens PL, Luo M, Liu K, San-Miguel J. PMID: 31270103; PMCID: PMC6754719.
View in:
PubMed Mentions:
42 Fields:
Translation:
HumansCTClinical Trials
-
Treatment Patterns and Clinical and Economic Outcomes in Patients With Newly Diagnosed Multiple Myeloma Treated With Lenalidomide- and/or Bortezomib-containing Regimens Without Stem Cell Transplant in a Real-world Setting. Clin Lymphoma Myeloma Leuk. 2019 10; 19(10):645-655.
Chari A, Parikh K, Ni Q, Abouzaid S. PMID: 31377207.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Phase 1 study of selinexor plus carfilzomib and dexamethasone for the treatment of relapsed/refractory multiple myeloma. Br J Haematol. 2019 08; 186(4):549-560.
Jakubowiak AJ, Jasielec JK, Rosenbaum CA, Cole CE, Chari A, Mikhael J, Nam J, McIver A, Severson E, Stephens LA, Tinari K, Rosebeck S, Zimmerman TM, Hycner T, Turowski A, Karrison T, Zonder JA. PMID: 31124580; PMCID: PMC6772147.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCTClinical Trials
-
Daratumumab plus carfilzomib and dexamethasone in patients with relapsed or refractory multiple myeloma. Blood. 2019 08 01; 134(5):421-431.
Chari A, Martinez-Lopez J, Mateos MV, Bladé J, Benboubker L, Oriol A, Arnulf B, Rodriguez-Otero P, Pineiro L, Jakubowiak A, de Boer C, Wang J, Clemens PL, Ukropec J, Schecter J, Lonial S, Moreau P. PMID: 31113777; PMCID: PMC6676132.
View in:
PubMed Mentions:
59 Fields:
Translation:
HumansCTClinical Trials
-
Management and outcomes of proteasome inhibitor associated chalazia and blepharitis: a case series. BMC Ophthalmol. 2019 May 14; 19(1):110.
Sklar BA, Gervasio KA, Leng S, Ghosh A, Chari A, Wu AY. PMID: 31088416; PMCID: PMC6518763.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Daratumumab-induced transient myopic shift. Am J Ophthalmol Case Rep. 2019 Mar; 13:116-118.
Mavrommatis MA, Jung H, Chari A, Barlogie B, Chelnis JG. PMID: 30619976; PMCID: PMC6312830.
View in:
PubMed Mentions:
2
-
Blood Transfusion Management for Patients Treated With Anti-CD38 Monoclonal Antibodies. Front Immunol. 2018; 9:2616.
Lancman G, Arinsburg S, Jhang J, Cho HJ, Jagannath S, Madduri D, Parekh S, Richter J, Chari A. PMID: 30498492; PMCID: PMC6249335.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
-
Results of an early access treatment protocol of daratumumab in United States patients with relapsed or refractory multiple myeloma. Cancer. 2018 11 15; 124(22):4342-4349.
Chari A, Lonial S, Mark TM, Krishnan AY, Stockerl-Goldstein KE, Usmani SZ, Londhe A, Etheredge D, Fleming S, Liu B, Ukropec J, Lin TS, Jagannath S, Nooka AK. PMID: 30395359; PMCID: PMC6587745.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCTClinical Trials
-
Daratumumab plus lenalidomide and dexamethasone versus lenalidomide and dexamethasone in relapsed or refractory multiple myeloma: updated analysis of POLLUX. Haematologica. 2018 12; 103(12):2088-2096.
Dimopoulos MA, San-Miguel J, Belch A, White D, Benboubker L, Cook G, Leiba M, Morton J, Ho PJ, Kim K, Takezako N, Moreau P, Kaufman JL, Sutherland HJ, Lalancette M, Magen H, Iida S, Kim JS, Prince HM, Cochrane T, Oriol A, Bahlis NJ, Chari A, O'Rourke L, Wu K, Schecter JM, Casneuf T, Chiu C, Soong D, Sasser AK, Khokhar NZ, Avet-Loiseau H, Usmani SZ. PMID: 30237262; PMCID: PMC6269302.
View in:
PubMed Mentions:
108 Fields:
Translation:
HumansCTClinical Trials
-
Imipridone ONC201: combination therapy in hematologic malignancies. Cell Cycle. 2018; 17(16):1947-1948.
Chari A, Barlogie B. PMID: 29929441; PMCID: PMC6224273.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Precision Medicine for Relapsed Multiple Myeloma on the Basis of an Integrative Multiomics Approach. JCO Precis Oncol. 2018; 2018.
Laganà A, Beno I, Melnekoff D, Leshchenko V, Madduri D, Ramdas D, Sanchez L, Niglio S, Perumal D, Kidd BA, Miotto R, Shaknovich R, Chari A, Cho HJ, Barlogie B, Jagannath S, Dudley JT, Parekh S. PMID: 30706044; PMCID: PMC6350920.
View in:
PubMed Mentions:
17 Fields:
-
Analysis of carfilzomib cardiovascular safety profile across relapsed and/or refractory multiple myeloma clinical trials. Blood Adv. 2018 07 10; 2(13):1633-1644.
Chari A, Stewart AK, Russell SD, Moreau P, Herrmann J, Banchs J, Hajek R, Groarke J, Lyon AR, Batty GN, Ro S, Huang M, Iskander KS, Lenihan D. PMID: 29991494; PMCID: PMC6039655.
View in:
PubMed Mentions:
29 Fields:
Translation:
Humans
-
Risk stratification of smoldering multiple myeloma: predictive value of free light chains and group-based trajectory modeling. Blood Adv. 2018 06 26; 2(12):1470-1479.
Wu V, Moshier E, Leng S, Barlogie B, Cho HJ, Jagannath S, Madduri D, Mazumdar M, Parekh S, Chari A. PMID: 29945937; PMCID: PMC6020804.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
-
Twice-weekly ixazomib in combination with lenalidomide-dexamethasone in patients with newly diagnosed multiple myeloma. Br J Haematol. 2018 07; 182(2):231-244.
Richardson PG, Hofmeister CC, Rosenbaum CA, Htut M, Vesole DH, Berdeja JG, Liedtke M, Chari A, Smith SD, Lebovic D, Raje N, Byrne C, Liao E, Gupta N, Bacco AD, Estevam J, Berg D, Baz R. PMID: 29938772; PMCID: PMC6055619.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCTClinical Trials
-
Treatment patterns and medication adherence among patients diagnosed with multiple myeloma and treated with panobinostat. Future Oncol. 2018 Sep; 14(21):2149-2160.
Chari A, Bhor M, Eldjerou L, Gilligan AM, Urniasz A, Globe D, Stetsovsky D, Varker H, Davis B, Bonafede M, Talcott J. PMID: 29846095.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Phase 1 trial of ibrutinib and carfilzomib combination therapy for relapsed or relapsed and refractory multiple myeloma. Leuk Lymphoma. 2018 11; 59(11):2588-2594.
Chari A, Larson S, Holkova B, Cornell RF, Gasparetto C, Karanes C, Matous JV, Niesvizky R, Valent J, Lunning M, Usmani SZ, Anderson LD, Chang L, Lee Y, Pak Y, Salman Z, Graef T, Bilotti E, Chhabra S. PMID: 29616843.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCTClinical Trials
-
Clinical Implications of Targeting XPO1-mediated Nuclear Export in Multiple Myeloma. Clin Lymphoma Myeloma Leuk. 2018 05; 18(5):335-345.
Gandhi UH, Senapedis W, Baloglu E, Unger TJ, Chari A, Vogl D, Cornell RF. PMID: 29610030.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansCells
-
Selective Inhibition of Nuclear Export With Oral Selinexor for Treatment of Relapsed or Refractory Multiple Myeloma. J Clin Oncol. 2018 03 20; 36(9):859-866.
Vogl DT, Dingli D, Cornell RF, Huff CA, Jagannath S, Bhutani D, Zonder J, Baz R, Nooka A, Richter J, Cole C, Vij R, Jakubowiak A, Abonour R, Schiller G, Parker TL, Costa LJ, Kaminetzky D, Hoffman JE, Yee AJ, Chari A, Siegel D, Fonseca R, Van Wier S, Ahmann G, Lopez I, Kauffman M, Shacham S, Saint-Martin JR, Picklesimer CD, Choe-Juliak C, Stewart AK. PMID: 29381435; PMCID: PMC6905485.
View in:
PubMed Mentions:
72 Fields:
Translation:
HumansCTClinical Trials
-
Prolonged Duration of Therapy Is Associated With Improved Survival in Patients Treated for Relapsed/Refractory Multiple Myeloma in Routine Clinical Care in the United States. Clin Lymphoma Myeloma Leuk. 2018 02; 18(2):152-160.
Hari P, Romanus D, Palumbo A, Luptakova K, Rifkin RM, Tran LM, Raju A, Farrelly E, Noga SJ, Blazer M, Chari A. PMID: 29395837.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
The effect of novel therapies in high-molecular-risk multiple myeloma. Clin Adv Hematol Oncol. 2017 Nov; 15(11):870-879.
Lancman G, Tremblay D, Barley K, Barlogie B, Cho HJ, Jagannath S, Madduri D, Moshier E, Parekh S, Chari A. PMID: 29200420; PMCID: PMC5993678.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Blood Transfusion Management and Transfusion-Related Outcomes in Daratumumab-Treated Patients With Relapsed or Refractory Multiple Myeloma. Clin Lymphoma Myeloma Leuk. 2018 01; 18(1):44-51.
Chari A, Arinsburg S, Jagannath S, Satta T, Treadwell I, Catamero D, Morgan G, Feng H, Uhlar C, Khan I, Doshi P, Usmani S. PMID: 29054515.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
A phase 2 study of panobinostat with lenalidomide and weekly dexamethasone in myeloma. Blood Adv. 2017 Aug 22; 1(19):1575-1583.
Chari A, Cho HJ, Dhadwal A, Morgan G, La L, Zarychta K, Catamero D, Florendo E, Stevens N, Verina D, Chan E, Leshchenko V, Laganà A, Perumal D, Mei AH, Tung K, Fukui J, Jagannath S, Parekh S. PMID: 29296798; PMCID: PMC5728465.
View in:
PubMed Mentions:
17 Fields:
-
Characteristics of Vitamin B12 Deficiency in Patients With Plasma Cell Disorders. Clin Lymphoma Myeloma Leuk. 2017 Dec; 17(12):e65-e69.
Braschi C, Doucette J, Chari A. PMID: 28757000.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
Prognostic Validation of SKY92 and Its Combination With ISS in an Independent Cohort of Patients With Multiple Myeloma. Clin Lymphoma Myeloma Leuk. 2017 09; 17(9):555-562.
van Beers EH, van Vliet MH, Kuiper R, de Best L, Anderson KC, Chari A, Jagannath S, Jakubowiak A, Kumar SK, Levy JB, Auclair D, Lonial S, Reece D, Richardson P, Siegel DS, Stewart AK, Trudel S, Vij R, Zimmerman TM, Fonseca R. PMID: 28735890.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
-
Daratumumab plus pomalidomide and dexamethasone in relapsed and/or refractory multiple myeloma. Blood. 2017 08 24; 130(8):974-981.
Chari A, Suvannasankha A, Fay JW, Arnulf B, Kaufman JL, Ifthikharuddin JJ, Weiss BM, Krishnan A, Lentzsch S, Comenzo R, Wang J, Nottage K, Chiu C, Khokhar NZ, Ahmadi T, Lonial S. PMID: 28637662; PMCID: PMC5570682.
View in:
PubMed Mentions:
180 Fields:
Translation:
HumansCTClinical Trials
-
Management of Patients With Hepatitis C Virus, Monoclonal Gammopathy of Undetermined Significance, and Multiple Myeloma. J Investig Med High Impact Case Rep. 2017 Apr-Jun; 5(2):2324709617696854.
Hannaford A, Del Bello D, Leng S, Chari A, Perumalswami P, Dieterich D, Branch A. PMID: 28748190; PMCID: PMC5510768.
View in:
PubMed Mentions: Fields:
-
Treating Multiple Myeloma Patients With Oral Therapies. Clin Lymphoma Myeloma Leuk. 2017 05; 17(5):243-251.
Kumar SK, Vij R, Noga SJ, Berg D, Brent L, Dollar L, Chari A. PMID: 28347676.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of hematologic malignancies: multiple myeloma, lymphoma, and acute leukemia. J Immunother Cancer. 2016; 4:90.
Boyiadzis M, Bishop MR, Abonour R, Anderson KC, Ansell SM, Avigan D, Barbarotta L, Barrett AJ, Van Besien K, Bergsagel PL, Borrello I, Brody J, Brufsky J, Cairo M, Chari A, Cohen A, Cortes J, Forman SJ, Friedberg JW, Fuchs EJ, Gore SD, Jagannath S, Kahl BS, Kline J, Kochenderfer JN, Kwak LW, Levy R, de Lima M, Litzow MR, Mahindra A, Miller J, Munshi NC, Orlowski RZ, Pagel JM, Porter DL, Russell SJ, Schwartz K, Shipp MA, Siegel D, Stone RM, Tallman MS, Timmerman JM, Van Rhee F, Waller EK, Welsh A, Werner M, Wiernik PH, Dhodapkar MV. PMID: 28018601; PMCID: PMC5168808.
View in:
PubMed Mentions:
14 Fields:
-
Incidence and risk of hypertension in patients newly treated for multiple myeloma: a retrospective cohort study. BMC Cancer. 2016 11 22; 16(1):912.
Chari A, Mezzi K, Zhu S, Werther W, Felici D, Lyon AR. PMID: 27876016; PMCID: PMC5120425.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansPHPublic Health
-
Incidence and Risk of Cardiac Events in Patients With Previously Treated Multiple Myeloma Versus Matched Patients Without Multiple Myeloma: An Observational, Retrospective, Cohort Study. Clin Lymphoma Myeloma Leuk. 2017 02; 17(2):89-96.e3.
Kistler KD, Kalman J, Sahni G, Murphy B, Werther W, Rajangam K, Chari A. PMID: 28025038.
View in:
PubMed Mentions:
28 Fields:
Translation:
Humans
-
A phase II trial of TBL-12 sea cucumber extract in patients with untreated asymptomatic myeloma. Br J Haematol. 2018 01; 180(2):296-298.
Chari A, Mazumder A, Lau K, Catamero D, Galitzeck Z, Jagannath S. PMID: 27714761.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
-
A phase 1 dose-escalation study of filanesib plus bortezomib and dexamethasone in patients with recurrent/refractory multiple myeloma. Cancer. 2016 Nov 15; 122(21):3327-3335.
Chari A, Htut M, Zonder JA, Fay JW, Jakubowiak AJ, Levy JB, Lau K, Burt SM, Tunquist BJ, Hilder BW, Rush SA, Walker DH, Ptaszynski M, Kaufman JL. PMID: 27433944; PMCID: PMC6857452.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCTClinical Trials
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Clinical efficacy of daratumumab monotherapy in patients with heavily pretreated relapsed or refractory multiple myeloma. Blood. 2016 07 07; 128(1):37-44.
Usmani SZ, Weiss BM, Plesner T, Bahlis NJ, Belch A, Lonial S, Lokhorst HM, Voorhees PM, Richardson PG, Chari A, Sasser AK, Axel A, Feng H, Uhlar CM, Wang J, Khan I, Ahmadi T, Nahi H. PMID: 27216216; PMCID: PMC4937359.
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PubMed Mentions:
176 Fields:
Translation:
HumansCTClinical Trials
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A pharmacokinetics and safety phase 1/1b study of oral ixazomib in patients with multiple myeloma and severe renal impairment or end-stage renal disease requiring haemodialysis. Br J Haematol. 2016 Sep; 174(5):748-59.
Gupta N, Hanley MJ, Harvey RD, Badros A, Lipe B, Kukreti V, Berdeja J, Yang H, Hui AM, Qian M, Zhang X, Venkatakrishnan K, Chari A. PMID: 27196567; PMCID: PMC5084759.
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PubMed Mentions:
20 Fields:
Translation:
HumansCTClinical Trials
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Validation and Utility of the Free Light Chain Assay in Pleural Effusions of Patients With Multiple Myeloma. Clin Lymphoma Myeloma Leuk. 2016 07; 16(7):e113-7.
Marron TU, Hanna MG, Ramanathan L, Chari A. PMID: 27349767.
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Humans
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Diagnostic Advances in Multiple Myeloma. Curr Hematol Malig Rep. 2016 Apr; 11(2):111-7.
Barley K, Chari A. PMID: 26922745.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Outcomes and management of lenalidomide-associated rash in patients with multiple myeloma. Leuk Lymphoma. 2016 11; 57(11):2510-5.
Barley K, He W, Agarwal S, Jagannath S, Chari A. PMID: 26943456.
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4 Fields:
Translation:
Humans
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Randomized multicenter phase 2 study of pomalidomide, cyclophosphamide, and dexamethasone in relapsed refractory myeloma. Blood. 2016 05 26; 127(21):2561-8.
Baz RC, Martin TG, Lin HY, Zhao X, Shain KH, Cho HJ, Wolf JL, Mahindra A, Chari A, Sullivan DM, Nardelli LA, Lau K, Alsina M, Jagannath S. PMID: 26932802.
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PubMed Mentions:
68 Fields:
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HumansCTClinical Trials
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Dual Targeting of CDK4 and ARK5 Using a Novel Kinase Inhibitor ON123300 Exerts Potent Anticancer Activity against Multiple Myeloma. Cancer Res. 2016 Mar 01; 76(5):1225-36.
Perumal D, Kuo PY, Leshchenko VV, Jiang Z, Divakar SK, Cho HJ, Chari A, Brody J, Reddy MV, Zhang W, Reddy EP, Jagannath S, Parekh S. PMID: 26873845; PMCID: PMC5968814.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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The outcomes of newly diagnosed elderly multiple myeloma patients treated at a single U.S. institution. Cancer Med. 2016 Mar; 5(3):500-5.
Bonomo L, Lue J, Jagannath S, Chari A. PMID: 26799254; PMCID: PMC4799960.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Daratumumab monotherapy in patients with treatment-refractory multiple myeloma (SIRIUS): an open-label, randomised, phase 2 trial. Lancet. 2016 Apr 09; 387(10027):1551-1560.
Lonial S, Weiss BM, Usmani SZ, Singhal S, Chari A, Bahlis NJ, Belch A, Krishnan A, Vescio RA, Mateos MV, Mazumder A, Orlowski RZ, Sutherland HJ, Bladé J, Scott EC, Oriol A, Berdeja J, Gharibo M, Stevens DA, LeBlanc R, Sebag M, Callander N, Jakubowiak A, White D, de la Rubia J, Richardson PG, Lisby S, Feng H, Uhlar CM, Khan I, Ahmadi T, Voorhees PM. PMID: 26778538.
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PubMed Mentions:
366 Fields:
Translation:
HumansCTClinical Trials
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Characterization of central nervous system multiple myeloma in the era of novel therapies. Leuk Lymphoma. 2016 07; 57(7):1709-13.
Majd N, Wei X, Demopoulos A, Hormigo A, Chari A. PMID: 26727654.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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CD34-Selected Allogeneic Hematopoietic Stem Cell Transplantation for Patients with Relapsed, High-Risk Multiple Myeloma. Biol Blood Marrow Transplant. 2016 Feb; 22(2):258-267.
Smith E, Devlin SM, Kosuri S, Orlando E, Landau H, Lesokhin AM, Chung DJ, Hassoun H, Lendvai N, Landgren O, Giralt S, Chari A, Jagannath S, Koehne G. PMID: 26325439; PMCID: PMC4975432.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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The characterization of adrenal insufficiency and identification of its risk factors in patients with plasma cell dyscrasias. Am J Hematol. 2015 Oct; 90(10):E202-3.
Tremblay D, Choudhury N, Ravikumar A, Levine AC, Chari A. PMID: 26178513.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Serum Free Light Chain Assessment Early After Stem Cell Transplantation as a Prognostic Factor in Multiple Myeloma. Clin Lymphoma Myeloma Leuk. 2015 Sep; 15(9):541-5.
Barley K, Tindle S, Bagiella E, Jagannath S, Chari A. PMID: 26119495.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Identification of markers that functionally define a quiescent multiple myeloma cell sub-population surviving bortezomib treatment. BMC Cancer. 2015 May 30; 15:444.
Adomako A, Calvo V, Biran N, Osman K, Chari A, Paton JC, Paton AW, Moore K, Schewe DM, Aguirre-Ghiso JA. PMID: 26025442; PMCID: PMC4448210.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
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Outcome of patients with multiple myeloma and hypotension during high-dose chemotherapy. Am J Hematol. 2015 Jun; 90(6):E125-7.
Biran N, Sehgal P, Sahni G, Doucette J, Chari A. PMID: 25732327.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Diagnostic utility of measuring free light chains in the cerebrospinal fluid of patients with multiple myeloma. Clin Lymphoma Myeloma Leuk. 2015 Jun; 15(6):e127-31.
Marron TU, Ramanathan L, Chari A. PMID: 25846395.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Case series discussion of cardiac and vascular events following carfilzomib treatment: possible mechanism, screening, and monitoring. BMC Cancer. 2014 Dec 04; 14:915.
Chari A, Hajje D. PMID: 25471129; PMCID: PMC4289164.
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PubMed Mentions:
37 Fields:
Translation:
Humans
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What we mean when we talk about MRD in myeloma. A review of current methods. Part 1 of a two-part series. Curr Hematol Malig Rep. 2014 Dec; 9(4):379-88.
Ely S, Biran N, Chari A. PMID: 25277219.
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1 Fields:
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Humans
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Controversies in the assessment of minimal residual disease in multiple myeloma: clinical significance of minimal residual disease negativity using highly sensitive techniques. Curr Hematol Malig Rep. 2014 Dec; 9(4):368-78.
Biran N, Ely S, Chari A. PMID: 25224462.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Imaging of extraosseous intracranial and intraspinal multiple myeloma, including central nervous system involvement. Clin Imaging. 2015 Mar-Apr; 39(2):213-9.
Shpilberg KA, Esses SJ, Fowkes ME, Chari A, Sacher M, Naidich TP. PMID: 25547625.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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State of the art imaging of multiple myeloma: comparative review of FDG PET/CT imaging in various clinical settings. Eur J Radiol. 2014 Dec; 83(12):2203-2223.
Mesguich C, Fardanesh R, Tanenbaum L, Chari A, Jagannath S, Kostakoglu L. PMID: 25308249.
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PubMed Mentions:
30 Fields:
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Humans
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Patients with newly diagnosed multiple myeloma and chromosome 1 amplification have poor outcomes despite the use of novel triplet regimens. Am J Hematol. 2014 Jun; 89(6):616-20.
Biran N, Malhotra J, Bagiella E, Cho HJ, Jagannath S, Chari A. PMID: 24616227.
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PubMed Mentions:
21 Fields:
Translation:
HumansCells
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A case of IgD myeloma representing a missed biclonal paraproteinemia or isotype switch in a patient previously diagnosed with IgA-lambda myeloma. Clin Chim Acta. 2013 Oct 21; 425:233-5.
Chepovetsky J, Chari A, Jagannath S, Ramanthan L. PMID: 23954772.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Risk stratification in multiple myeloma, part 1: characterization of high-risk disease. Clin Adv Hematol Oncol. 2013 Aug; 11(8):489-503.
Biran N, Jagannath S, Chari A. PMID: 24518420.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Complete remission achieved with single agent CNTO 328, an anti-IL-6 monoclonal antibody, in relapsed and refractory myeloma. Clin Lymphoma Myeloma Leuk. 2013 Jun; 13(3):333-7.
Chari A, Pri-Chen H, Jagannath S. PMID: 23313067.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Risk stratification in multiple myeloma, part 2: the significance of genetic risk factors in the era of currently available therapies. Clin Adv Hematol Oncol. 2013; 11(9):578-83.
Biran N, Jagannath S, Chari A. PMID: 24518521.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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A case report of chronic myelogenous leukemia in a patient with multiple myeloma and a review of the literature. Clin Lymphoma Myeloma Leuk. 2013 Apr; 13(2):175-9.
Ragupathi L, Najfeld V, Chari A, Petersen B, Jagannath S, Mascarenhas J. PMID: 23168212.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Misdiagnosis of non-hodgkin lymphoma as multiple myeloma. J Clin Oncol. 2012 Dec 10; 30(35):e364-7.
Barley K, Harris JA, Diefenbach C, Jagannath S, Chari A. PMID: 23109698.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Safety and efficacy of triplet regimens in newly diagnosed light chain amyloidosis. Clin Lymphoma Myeloma Leuk. 2013 Feb; 13(1):55-61.
Chari A, Barley K, Jagannath S, Osman K. PMID: 23098888.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Erectile dysfunction associated with bortezomib treatment in a patient with multiple myeloma and amyloidosis. Clin Lymphoma Myeloma Leuk. 2013 Jun; 13(3):331-2.
Pri-Chen H, Chari A. PMID: 23084404.
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Risk stratification of plasma cell neoplasm: insights from plasma cell-specific cytoplasmic immunoglobulin fluorescence in situ hybridization (cIg FISH) vs. conventional FISH. Clin Lymphoma Myeloma Leuk. 2012 Oct; 12(5):366-74.
Dong H, Yang HS, Jagannath S, Stephenson CF, Brenholz P, Mazumder A, Chari A. PMID: 22658896.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Proteasome inhibition and its therapeutic potential in multiple myeloma. Biologics. 2010 Sep 28; 4:273-87.
Chari A, Mazumder A, Jagannath S. PMID: 21116326; PMCID: PMC2990320.
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10