Soumaya Zlitni • UCSF Profiles

Soumaya Zlitni, PhD

Title(s)	Assistant Professor, Medicine
School	School of Medicine
Address	513 Parnassus Avenue, HSE, #1136C San Francisco CA 94143
Email	soumaya.zlitni@ucsf.edu
Pronouns	She/Her/Hers
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Biography

education and training

McMaster University, Canada	PhD	08/2014	Biochemistry
Stanford University, USA	Postdoc	08/2024	The human microbiome

Overview

overview

In the Zlitni lab, we study the role of microbial communication in the assembly and function of the human microbiome, with a particular focus on how these interactions protect the host from infectious and chronic diseases. Trillions of microbes live on and inside our bodies, forming what can be described as an 'organ' that plays a critical role in health, physiology, and defense against pathogens. One of the field's biggest questions is how these microbes come together to form communities that perform essential functions for the host.
We combine microbiology, biochemistry, and advanced -omics technologies to investigate how microbial communication shapes both the assembly and function of the human microbiome. In addition to uncovering fundamental insights into microbial communication, we aim to leverage this knowledge to develop live biotherapeutic interventions that restore microbiota resilience when it has been compromised.

keywords

Human microbiome, Microbial communication, Quorum sensing, Metagenomics, Transcriptomics, Metabolomics

ORNG Applications

Featured Publications

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Dual quorum-sensing control of purine biosynthesis drives pathogenic fitness of Enterococcus faecalis. bioRxiv. 2024 Aug 13. Zlitni S, Bowden S, Sberro H, Torres MDT, Vaughan JM, Pinto AFM, Pinto Y, Fernandez D, Röst H, Saghatelian A, de la Fuente-Nunez C, Bhatt AS. PMID: 39185165; PMCID: PMC11343167.

View in: PubMed Mentions:
Metabolic diversity in commensal protists regulates intestinal immunity and trans-kingdom competition. Cell. 2024 01 04; 187(1):62-78.e20. Gerrick ER, Zlitni S, West PT, Carter MM, Mechler CM, Olm MR, Caffrey EB, Li JA, Higginbottom SK, Severyn CJ, Kracke F, Spormann AM, Sonnenburg JL, Bhatt AS, Howitt MR. PMID: 38096822.

View in: PubMed Mentions: 7 Fields:
Cel Cell Biology
Translation:Humans Animals
Strain-resolved microbiome sequencing reveals mobile elements that drive bacterial competition on a clinical timescale. Genome Med. 2020 05 29; 12(1):50. Zlitni S, Bishara A, Moss EL, Tkachenko E, Kang JB, Culver RN, Andermann TM, Weng Z, Wood C, Handy C, Ji HP, Batzoglou S, Bhatt AS. PMID: 32471482; PMCID: PMC7260799.

View in: PubMed Mentions: 24 Fields:
Gen Genetics
Translation:Humans Cells