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Srividhya Swaminathan, PhD

Photo of Srividhya Swaminathan, PhD
Title(s)Postdoctoral Scholar, Pediatrics
SchoolSchool of Medicine
Address1550 Fourth Street, #540
San Francisco CA 94158
ORCID ORCID Icon0000-0002-0750-3650 Additional info
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    Collapse Biography 
    Collapse education and training
    The University of QueenslandPh.D2024Immunology
    Vellore Institute of Technology M.Tech2018Biotechnology
    SASTRA University B.Tech2016Biotechnology

    Collapse Overview 
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    Dr. Swaminathan is an aspiring immunologist dedicated to bridging the gap between fundamental research and clinical application. She currently serves as a Postdoctoral Scholar at the University of California, San Francisco, where she joined the Prahl Lab in 2024. Her postdoctoral work is centered on pioneering new analytical methods to dissect the complexities of the pediatric immune system. By investigating immune responses to key childhood vaccines like those for COVID-19 and RSV, she aims to provide critical insights that will inform the development of next-generation vaccines for the world's youngest and most vulnerable populations.

    Dr. Swaminathan’s expertise is built on a foundation of high-impact doctoral research. While earning her PhD in Immunology from The University of Queensland at the QIMR Berghofer Medical Research Institute, she contributed to a project that culminated in a remarkable achievement: the design and preclinical validation of an allogeneic T-cell therapy for treating severe SARS-CoV-2 infections in immunocompromised individuals.

    With a unique background that spans academic research and industry standards, including experience in GLP and GMP-compliant environments, Dr. Swaminathan possesses a robust technical skillset in T cell therapy development, flow cytometry, and virology. Her work is driven by a commitment to leveraging the power of immunology to create tangible solutions for global health challenges.
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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Allogeneic 'off-the-shelf' SARS-CoV-2-specific adoptive T-cell therapy for refractory viral infection and end organ disease. Clin Transl Immunology. 2025; 14(6):e70038. Henden AS, Lineburg KE, Panikkar A, Mahajan A, Nelles R, Wright E, Crooks P, Raju J, Le Texier L, Swaminathan S, Beagley L, Best S, Solomon M, Reddiex H, Kennedy G, Tey SK, Neller MA, Khanna R, Smith C. PMID: 40497132; PMCID: PMC12151542.
      View in: PubMed   Mentions:
    2. Breakthrough SARS-COV-2 infection induces broad anti-viral T cell immunity. iScience. 2023 Dec 15; 26(12):108474. Lineburg KE, Crooks P, Raju J, Le Texier L, Khaledi P, Berry K, Swaminathan S, Panikkar A, Rehan S, Guppy-Coles K, Neller MA, Khanna R, Smith C. PMID: 38077128; PMCID: PMC10698266.
      View in: PubMed   Mentions: 3  
    3. Ablation of CD8+ T cell recognition of an immunodominant epitope in SARS-CoV-2 Omicron variants BA.1, BA.2 and BA.3. Nat Commun. 2022 10 27; 13(1):6387. Swaminathan S, Lineburg KE, Panikkar A, Raju J, Murdolo LD, Szeto C, Crooks P, Le Texier L, Rehan S, Dewar-Oldis MJ, Barnard PJ, Ambalathingal GR, Neller MA, Short KR, Gras S, Khanna R, Smith C. PMID: 36302758; PMCID: PMC9607807.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    4. Limited Recognition of Highly Conserved Regions of SARS-CoV-2. Microbiol Spectr. 2022 02 23; 10(1):e0278021. Swaminathan S, Lineburg KE, Ambalathingal GR, Crooks P, Grant EJ, Mohan SV, Raju J, Panikkar A, Le Texier L, Tong ZWM, Chew KY, Neller MA, Short KR, Gowda H, Gras S, Khanna R, Smith C. PMID: 35196796; PMCID: PMC8865427.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    5. SARS-CoV-2-specific T cells generated for adoptive immunotherapy are capable of recognizing multiple SARS-CoV-2 variants. PLoS Pathog. 2022 02; 18(2):e1010339. Panikkar A, Lineburg KE, Raju J, Chew KY, Ambalathingal GR, Rehan S, Swaminathan S, Crooks P, Le Texier L, Beagley L, Best S, Solomon M, Matthews KK, Srihari S, Neller MA, Short KR, Khanna R, Smith C. PMID: 35157735; PMCID: PMC8880869.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    6. Rapid whole-blood assay to detect SARS-CoV-2-specific memory T-cell immunity following a single dose of AstraZeneca ChAdOx1-S COVID-19 vaccine. Clin Transl Immunology. 2021; 10(8):e1326. Lineburg KE, Neller MA, Ambalathingal GR, Le Texier L, Raju J, Swaminathan S, Lekieffre L, Smith C, Rehan S, Crooks P, Panikkar A, Srihari S, Khanna R, Smith C. PMID: 34408875; PMCID: PMC8360255.
      View in: PubMed   Mentions: 8  
    7. CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses. Immunity. 2021 05 11; 54(5):1055-1065.e5. Lineburg KE, Grant EJ, Swaminathan S, Chatzileontiadou DSM, Szeto C, Sloane H, Panikkar A, Raju J, Crooks P, Rehan S, Nguyen AT, Lekieffre L, Neller MA, Tong ZWM, Jayasinghe D, Chew KY, Lobos CA, Halim H, Burrows JM, Riboldi-Tunnicliffe A, Chen W, D'Orsogna L, Khanna R, Short KR, Smith C, Gras S. PMID: 33945786; PMCID: PMC8043652.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansCells
    8. Rapid detection of SARS-CoV-2-specific memory T-cell immunity in recovered COVID-19 cases. Clin Transl Immunology. 2020; 9(12):e1219. Lineburg KE, Srihari S, Altaf M, Swaminathan S, Panikkar A, Raju J, Crooks P, Ambalathingal GR, Martins JP, Matthews KK, Neller MA, Khanna R, Smith C. PMID: 33312565; PMCID: PMC7720530.
      View in: PubMed   Mentions: 16