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Daniel Fried, PhD

TitleProfessor
SchoolUCSF School of Dentistry
DepartmentPreventive & Restor Dent Sci
Address707 Parnassus Ave
San Francisco CA 94143
Phone415-502-6641
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    Collapse Research 
    Collapse Research Activities and Funding
    Selective Ablation of Dental Caries and Composites
    NIH/NIDCR R01DE019631Sep 1, 2009 - Mar 31, 2018
    Role: Principal Investigator
    Clinical Assessment of Tooth Demineralization &Remineralization with PS-OCT
    NIH/NIDCR R01DE017869Aug 15, 2006 - Jul 31, 2015
    Role: Principal Investigator
    Early Caries Detection with Near-IR Light
    NIH/NIDCR R01DE014698Aug 1, 2002 - Apr 30, 2017
    Role: Principal Investigator
    Laser Ablation of Dental Hard Tissues
    NIH/NIDCR R01DE014554Jun 1, 2002 - May 31, 2008
    Role: Principal Investigator
    MULTIPURPOSE CO2 TEA LASER FOR DENTAL APPLICATIONS
    NIH/NIDCR R41DE012971Aug 1, 2000 - Jul 31, 2001
    Role: Principal Investigator
    IR LASER ABLATION OF DENTAL HARD TISSUE
    NIH/NIDCR R29DE012091Aug 1, 1997 - May 31, 2003
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Kang H, Darling CL, Fried D. Use of an optical clearing agent to enhance the visibility of subsurface structures and lesions from tooth occlusal surfaces. J Biomed Opt. 2016 Aug 1; 21(8):81206. PMID: 27071709.
      View in: PubMed
    2. Algarni A, Kang H, Fried D, Eckert GJ, Hara AT. Enamel Thickness Determination by Optical Coherence Tomography: In vitro Validation. Caries Res. 2016; 50(4):400-6. PMID: 27454764.
      View in: PubMed
    3. Simon JC, Lucas SA, Staninec M, Tom H, Chan KH, Darling CL, Cozin MJ, Lee RC, Fried D. Near-IR transillumination and reflectance imaging at 1,300?nm and 1,500-1,700?nm for in vivo caries detection. Lasers Surg Med. 2016 Nov; 48(9):828-836. PMID: 27389018.
      View in: PubMed
    4. Lee RC, Darling CL, Staninec M, Ragadio A, Fried D. Activity assessment of root caries lesions with thermal and near-IR imaging methods. J Biophotonics. 2016 Apr 6. PMID: 27060450.
      View in: PubMed
    5. Lee RC, Darling CL, Fried D. Assessment of remineralized dentin lesions with thermal and near-infrared reflectance imaging. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 27006522.
      View in: PubMed
    6. Simon JC, Darling CL, Fried D. A system for simultaneous near-infrared reflectance and transillumination imaging of occlusal carious lesions. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 27006524.
      View in: PubMed
    7. Almaz EC, Simon JC, Fried D, Darling CL. Influence of stains on lesion contrast in the pits and fissures of tooth occlusal surfaces from 800-1600-nm. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 26997740.
      View in: PubMed
    8. Fried WA, Chan KH, Darling CL, Fried D. Selective removal of dental composite with a diode-pumped Er:YAG laser. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 26997741.
      View in: PubMed
    9. Yi I, Chan KH, Tsuji GH, Staninec M, Darling CL, Fried D. Selective removal of esthetic composite restorations with spectral guided laser ablation. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 26997742.
      View in: PubMed
    10. Tam W, Lee RC, Lin B, Simon JC, Fried D. Assessment of simulated lesions on primary teeth with near-infrared imaging. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 26997743.
      View in: PubMed
    11. Chan KH, Jew JM, Fried D. A new sealed RF-excited CO2 laser for enamel ablation operating at 9.4-µm with a pulse duration of 26-µs. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 27006521.
      View in: PubMed
    12. Kim JW, Chan KH, Fried D. Evaluation of enamel surface modification using PS-OCT after laser treatment to increase resistance to demineralization. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 27006523.
      View in: PubMed
    13. Kang H, Darling CL, Fried D. Enhancement of OCT images with vinyl polysiloxane (VPS). Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 27011417.
      View in: PubMed
    14. Simon JC, A Lucas S, Lee RC, Darling CL, Staninec M, Vaderhobli R, Pelzner R, Fried D. Near-infrared imaging of secondary caries lesions around composite restorations at wavelengths from 1300-1700-nm. Dent Mater. 2016 Apr; 32(4):587-95. PMID: 26876234.
      View in: PubMed
    15. Tom H, Chan KH, Darling CL, Fried D. Near-IR image-guided laser ablation of demineralization on tooth occlusal surfaces. Lasers Surg Med. 2016 Jan; 48(1):52-61. PMID: 26763111.
      View in: PubMed
    16. Lee RC, Darling CL, Fried D. Assessment of remineralization via measurement of dehydration rates with thermal and near-IR reflectance imaging. J Dent. 2015 Aug; 43(8):1032-42. PMID: 25862275; PMCID: PMC4509858 [Available on 08/01/16].
    17. Chan KH, Tom H, Darling CL, Fried D. Serial removal of caries lesions from tooth occlusal surfaces using near-IR image-guided IR laser ablation. Proc SPIE Int Soc Opt Eng. 2015 Feb 24; 9306. PMID: 25914499.
      View in: PubMed
    18. Chung LC, Tom H, Chan KH, Simon JC, Fried D, Darling CL. Image-guided removal of occlusal caries lesions with a ?= 9.3-µm CO2 laser using near-IR transillumination. Proc SPIE Int Soc Opt Eng. 2015 Feb 24; 9306. PMID: 25914498.
      View in: PubMed
    19. Yan R, Chan KH, Tom H, Simon JC, Darling CL, Fried D. Selective removal of dental caries with a diode-pumped Er:YAG laser. Proc SPIE Int Soc Opt Eng. 2015 Feb 24; 9306. PMID: 25914496.
      View in: PubMed
    20. Simon JC, Lucas S, Lee R, Darling CL, Staninec M, Vanderhobli R, Pelzner R, Fried D. In vitro near-infrared imaging of natural secondary caries. Proc SPIE Int Soc Opt Eng. 2015 Feb 24; 9306. PMID: 25914495.
      View in: PubMed
    21. Lee RC, Darling CL, Fried D. Assessment of remineralization in simulated enamel lesions via dehydration with near-IR reflectance imaging. Proc SPIE Int Soc Opt Eng. 2015 Feb 24; 9306. PMID: 25914494.
      View in: PubMed
    22. Kang H, Darling CL, Tom H, Fried D. Enhanced detection of dentinal lesions in OCT images using the RKT transformation. Proc SPIE Int Soc Opt Eng. 2015 Feb 24; 9306. PMID: 25914493.
      View in: PubMed
    23. Chan KH, Tom H, Darling CL, Fried D. A method for monitoring enamel erosion using laser irradiated surfaces and optical coherence tomography. Lasers Surg Med. 2014 Nov; 46(9):672-8. PMID: 25147133.
      View in: PubMed
    24. Lee RC, Kang H, Darling CL, Fried D. Automated assessment of the remineralization of artificial enamel lesions with polarization-sensitive optical coherence tomography. Biomed Opt Express. 2014 Sep 1; 5(9):2950-62. PMID: 25401009; PMCID: PMC4230881.
    25. Nee A, Chan K, Kang H, Staninec M, Darling CL, Fried D. Longitudinal monitoring of demineralization peripheral to orthodontic brackets using cross polarization optical coherence tomography. J Dent. 2014 May; 42(5):547-55. PMID: 24561340; PMCID: PMC4007269.
    26. Chan KH, Tom H, Fried D. Monitoring the inhibition of erosion by a CO2 laser with OCT. Proc SPIE Int Soc Opt Eng. 2014 Feb 18; 8929:89290F. PMID: 24817804.
      View in: PubMed
    27. Chan AC, Darling CL, Chan KH, Fried D. Attenuation of near-IR light through dentin at wavelengths from 1300-1650-nm. Proc SPIE Int Soc Opt Eng. 2014 Feb 18; 8929:89290M. PMID: 24839373.
      View in: PubMed
    28. Lee RC, Darling CL, Fried D. Automated detection of remineralization in simulated enamel lesions with PS-OCT. Proc SPIE Int Soc Opt Eng. 2014 Feb 18; 8929:89290E. PMID: 25075267.
      View in: PubMed
    29. Tom H, Chan KH, Darling CL, Fried D. Near-IR imaging of demineralization under sealants. Proc SPIE Int Soc Opt Eng. 2014 Feb 18; 8929:89290S. PMID: 24817807.
      View in: PubMed
    30. Fried WA, Simon JC, Lucas S, Chan KH, Darling CL, Staninec M, Fried D. Near-IR imaging of cracks in teeth. Proc SPIE Int Soc Opt Eng. 2014 Feb 18; 8929:89290Q. PMID: 24817806.
      View in: PubMed
    31. Kang H, Darling CL, Fried D. Enhancing the detection of hidden occlusal caries lesions with OCT using high index liquids. Proc SPIE Int Soc Opt Eng. 2014 Feb 18; 8929:89290O. PMID: 24817805.
      View in: PubMed
    32. Simon JC, Lucas SA, Staninec M, Tom H, Chan KH, Darling CL, Fried D. Transillumination and reflectance probes for in vivo near-IR imaging of dental caries. Proc SPIE Int Soc Opt Eng. 2014 Feb 18; 8929:89290D. PMID: 24817803.
      View in: PubMed
    33. Lamantia NR, Tom H, Chan KH, Simon JC, Darling CL, Fried D. High contrast optical imaging methods for image guided laser ablation of dental caries lesions. Proc SPIE Int Soc Opt Eng. 2014 Feb 18; 8929. PMID: 24791129.
      View in: PubMed
    34. Chan KH, Hirasuna K, Fried D. Analysis of enamel surface damage after selective laser ablation of composite from tooth surfaces. Photonics Lasers Med. 2014 Feb 1; 3(1):37-45. PMID: 24707453.
      View in: PubMed
    35. Tom H, Simon JC, Chan KH, Darling CL, Fried D. Near-infrared imaging of demineralization under sealants. J Biomed Opt. 2014; 19(7):77003. PMID: 25036214; PMCID: PMC4103580.
    36. Simon JC, Chan KH, Darling CL, Fried D. Multispectral near-IR reflectance imaging of simulated early occlusal lesions: variation of lesion contrast with lesion depth and severity. Lasers Surg Med. 2014 Mar; 46(3):203-15. PMID: 24375543; PMCID: PMC3961544.
    37. Chan KH, Chan AC, Fried WA, Simon JC, Darling CL, Fried D. Use of 2D images of depth and integrated reflectivity to represent the severity of demineralization in cross-polarization optical coherence tomography. J Biophotonics. 2015 Jan; 8(1-2):36-45. PMID: 24307350.
      View in: PubMed
    38. Fried WA, Fried D, Chan KH, Darling CL. High contrast reflectance imaging of simulated lesions on tooth occlusal surfaces at near-IR wavelengths. Lasers Surg Med. 2013 Oct; 45(8):533-41. PMID: 23857066; PMCID: PMC4472445.
    39. Chan KH, Chan AC, Darling CL, Fried D. Methods for Monitoring Erosion Using Optical Coherence Tomography. Proc SPIE Int Soc Opt Eng. 2013 Mar 25; 8566:856606. PMID: 24465117.
      View in: PubMed
    40. Fried WA, Fried D, Chan KH, Darling CL. Imaging Early Demineralization on Tooth Occlusal Surfaces with a High Definition InGaAs Camera. Proc SPIE Int Soc Opt Eng. 2013 Mar 25; 8566. PMID: 24357911.
      View in: PubMed
    41. Fried D, Staninec M, Darling CL, Chan KH, Pelzner RB. Clinical Monitoring of Early Caries Lesions using Cross Polarization Optical Coherence Tomography. Proc SPIE Int Soc Opt Eng. 2013 Mar 25; 8566. PMID: 24353384.
      View in: PubMed
    42. Kang H, Chan K, Darling CL, Fried D. Monitoring the Remineralization of Early Simulated Lesions using a pH Cycling Model with CP-OCT. Proc SPIE Int Soc Opt Eng. 2013 Mar 25; 8566. PMID: 24353383.
      View in: PubMed
    43. Kang H, Darling CL, Fried D. Nondestructive Monitoring of the Repair of Natural Occlusal Lesions using Cross - Polarization Optical Coherence Tomography. Proc SPIE Int Soc Opt Eng. 2012 Feb 9; 8208. PMID: 23538837.
      View in: PubMed
    44. Darling CL, Staninec M, Chan KH, Kang H, Fried D. Remineralization of Root Caries Monitored Using Cross-Polarization Optical Coherence Tomography. Proc SPIE Int Soc Opt Eng. 2012 Feb 9; 8208. PMID: 24357904.
      View in: PubMed
    45. Fried D, Staninec M, Darling C, Kang H, Chan K. Monitoring tooth demineralization using a cross polarization optical coherence tomographic system with an integrated MEMS scanner. Proc SPIE Int Soc Opt Eng. 2012 Feb 9; 8208. PMID: 24357905.
      View in: PubMed
    46. Chan KH, Fried D. Selective Removal of Demineralization Using Near Infrared Cross Polarization Reflectance and a Carbon Dioxide Laser. Proc SPIE Int Soc Opt Eng. 2012 Feb 9; 8208. PMID: 24357906.
      View in: PubMed
    47. Nahm BJ, Kang H, Chan K, Fried D. Investigation of Acid-Etched CO2 Laser Ablated Enamel Surfaces Using Polarization Sensitive Optical Coherence Tomography. Proc SPIE Int Soc Opt Eng. 2012 Feb 9; 8208. PMID: 23539418.
      View in: PubMed
    48. Kang H, Darling CL, Fried D. Nondestructive monitoring of the repair of enamel artificial lesions by an acidic remineralization model using polarization-sensitive optical coherence tomography. Dent Mater. 2012 May; 28(5):488-94. PMID: 22204914; PMCID: PMC3319335.
    49. Staninec M, Douglas SM, Darling CL, Chan K, Kang H, Lee RC, Fried D. Non-destructive clinical assessment of occlusal caries lesions using near-IR imaging methods. Lasers Surg Med. 2011 Dec; 43(10):951-9. PMID: 22109697; PMCID: PMC3241877.
    50. Chung S, Fried D, Staninec M, Darling CL. Multispectral near-IR reflectance and transillumination imaging of teeth. Biomed Opt Express. 2011 Oct 1; 2(10):2804-14. PMID: 22025986; PMCID: PMC3191447.
    51. Chan KH, Hirasuna K, Fried D. Rapid and selective removal of composite from tooth surfaces with a 9.3 µm CO2 laser using spectral feedback. Lasers Surg Med. 2011 Sep; 43(8):824-32. PMID: 21956630.
      View in: PubMed
    52. Nguyen D, Chang K, Hedayatollahnajafi S, Staninec M, Chan K, Lee R, Fried D. High-speed scanning ablation of dental hard tissues with a ? = 9.3 µm CO2 laser: adhesion, mechanical strength, heat accumulation, and peripheral thermal damage. J Biomed Opt. 2011 Jul; 16(7):071410. PMID: 21806256; PMCID: PMC3160453.
    53. Rechmann P, Fried D, Le CQ, Nelson G, Rapozo-Hilo M, Rechmann BM, Featherstone JD. Caries inhibition in vital teeth using 9.6-µm CO2-laser irradiation. J Biomed Opt. 2011 Jul; 16(7):071405. PMID: 21806251; PMCID: PMC3144970.
    54. Kang H, Darling CL, Fried D. Repair of Artificial Lesions using an Acidic Remineralization Model Monitored with Cross - Polarization Optical Coherence Tomography. Proc SPIE Int Soc Opt Eng. 2011 Jan 23; 7884(78840Q). PMID: 21785533.
      View in: PubMed
    55. Fried D, Staninec M, Darling CL, Lee C, Kang H, Chan KH. In vivo Near-IR Imaging of Occlusal Lesions at 1310-nm. Proc SPIE Int Soc Opt Eng. 2011 Jan 23; 7884(78840B). PMID: 21785532.
      View in: PubMed
    56. Chan KH, Fried D. Selective Removal of Dental Composite using a Rapidly Scanned Carbon Dioxide Laser. Proc SPIE Int Soc Opt Eng. 2011; 7884:78840R1-78840R5. PMID: 21927546.
      View in: PubMed
    57. Chang KK, Staninec M, Chan KH, Fried D. Adhesion studies on dental enamel surfaces irradiated by a rapidly scanned carbon dioxide laser. Proc SPIE Int Soc Opt Eng. 2011 Jan 1; 7884. PMID: 21998494.
      View in: PubMed
    58. Darling CL, Chan KH, Fried D. Polarization Resolved Near-IR Imaging of Sound and Carious Dental Enamel. Proc SPIE Int Soc Opt Eng. 2011 Jan 1; 7884. PMID: 22399837.
      View in: PubMed
    59. Chung S, Fried D, Staninec M, Darling CL. Near infrared imaging of teeth at wavelengths between 1200 and 1600 nm. Proc SPIE Int Soc Opt Eng. 2011 Jan 1; 7884. PMID: 22399836.
      View in: PubMed
    60. Louie T, Lee C, Hsu D, Hirasuna K, Manesh S, Staninec M, Darling CL, Fried D. Clinical assessment of early tooth demineralization using polarization sensitive optical coherence tomography. Lasers Surg Med. 2010 Dec; 42(10):738-45. PMID: 21246578; PMCID: PMC3058417.
    61. Kang H, Jiao JJ, Lee C, Le MH, Darling CL, Fried D. Nondestructive Assessment of Early Tooth Demineralization Using Cross-Polarization Optical Coherence Tomography. IEEE J Sel Top Quantum Electron. 2010 7; 16(4):870-876. PMID: 21660217.
      View in: PubMed
    62. Lee C, Lee D, Darling CL, Fried D. Nondestructive assessment of the severity of occlusal caries lesions with near-infrared imaging at 1310 nm. J Biomed Opt. 2010 Jul-Aug; 15(4):047011. PMID: 20799842; PMCID: PMC2929264.
    63. Staninec M, Lee C, Darling CL, Fried D. In vivo near-IR imaging of approximal dental decay at 1,310 nm. Lasers Surg Med. 2010 Apr; 42(4):292-8. PMID: 20432277; PMCID: PMC3195334.
    64. Maung LH, Lee C, Fried D. Near-IR Imaging of Thermal Changes in Enamel during Laser Ablation. Proc SPIE Int Soc Opt Eng. 2010 Mar 5; 7546(1). PMID: 21935291.
      View in: PubMed
    65. Stahl J, Kang H, Fried D. Imaging Simulated Secondary Caries Lesions with Cross Polarization OCT. Proc SPIE Int Soc Opt Eng. 2010 Mar 5; 7549:754905. PMID: 21892257.
      View in: PubMed
    66. Lee C, Darling CL, Fried D. In vitro near-infrared imaging of occlusal dental caries using germanium enhanced CMOS camera. Proc SPIE Int Soc Opt Eng. 2010 Mar 1; 7549. PMID: 22162916.
      View in: PubMed
    67. Kang H, Jiao JJ, Lee C, Darling CL, Fried D. Imaging early demineralization with PS-OCT. Proc SPIE Int Soc Opt Eng. 2010 Jan 1; 7549. PMID: 22399835.
      View in: PubMed
    68. Douglas SM, Fried D, Darling CL. Imaging Natural Occlusal Caries Lesions with Optical Coherence Tomography. Proc SPIE Int Soc Opt Eng. 2010; 7549:75490N. PMID: 22228981.
      View in: PubMed
    69. Darling CL, Jiao JJ, Lee C, Kang H, Fried D. Near-IR Polarization Imaging of Sound and Carious Dental Enamel. Proc SPIE Int Soc Opt Eng. 2010; 7549:75490L. PMID: 22228980.
      View in: PubMed
    70. Le MH, Darling CL, Fried D. Automated analysis of lesion depth and integrated reflectivity in PS-OCT scans of tooth demineralization. Lasers Surg Med. 2010 Jan; 42(1):62-8. PMID: 20077486; PMCID: PMC3192502.
    71. Tao YC, Fried D. Near-infrared image-guided laser ablation of dental decay. J Biomed Opt. 2009 Sep-Oct; 14(5):054045. PMID: 19895146; PMCID: PMC2782366.
    72. Manesh SK, Darling CL, Fried D. Nondestructive assessment of dentin demineralization using polarization-sensitive optical coherence tomography after exposure to fluoride and laser irradiation. J Biomed Mater Res B Appl Biomater. 2009 Aug; 90(2):802-12. PMID: 19283826; PMCID: PMC2707504.
    73. Manesh SK, Darling CL, Fried D. Polarization-sensitive optical coherence tomography for the nondestructive assessment of the remineralization of dentin. J Biomed Opt. 2009 Jul-Aug; 14(4):044002. PMID: 19725714.
      View in: PubMed
    74. Staninec M, Darling CL, Goodis HE, Pierre D, Cox DP, Fan K, Larson M, Parisi R, Hsu D, Manesh SK, Ho C, Hosseini M, Fried D. Pulpal effects of enamel ablation with a microsecond pulsed lambda = 9.3-microm CO2 laser. Lasers Surg Med. 2009 Apr; 41(4):256-63. PMID: 19347946; PMCID: PMC3188421.
    75. Lee C, Hsu DJ, Le MH, Darling CL, Fried D. Non-destructive measurement of demineralization & remineralization in the occlusal pits and fissures of extracted 3 molars with PS-OCT. Proc SPIE Int Soc Opt Eng. 2009 Mar 6; 7162(1). PMID: 21935289.
      View in: PubMed
    76. Wu J, Fried D. High contrast near-infrared polarized reflectance images of demineralization on tooth buccal and occlusal surfaces at lambda = 1310-nm. Lasers Surg Med. 2009 Mar; 41(3):208-13. PMID: 19291753; PMCID: PMC2689647.
    77. Le MH, Darling CL, Fried D. Methods for calculating the severity of demineralization on tooth surfaces from PS-OCT scans. Proc SPIE Int Soc Opt Eng. 2009 Feb 18; 7162(1). PMID: 21935290.
      View in: PubMed
    78. Darling CL, Le CQ, Featherstone JD, Fried D. An Automated Digital Microradiography System for Assessing Tooth Demineralization. Proc SPIE Int Soc Opt Eng. 2009 Feb 18; 7162(1). PMID: 21935288.
      View in: PubMed
    79. Hedayatollahnajafi S, Staninec M, Watanabe L, Lee C, Fried D. Dentin bond strength after ablation using a CO(2) laser operating at high pulse repetition rates. Proc SPIE Int Soc Opt Eng. 2009 Feb 18; 7162:71620F. PMID: 21892256.
      View in: PubMed
    80. Lee C, Darling CL, Fried D. Polarization-sensitive optical coherence tomographic imaging of artificial demineralization on exposed surfaces of tooth roots. Dent Mater. 2009 Jun; 25(6):721-8. PMID: 19167052; PMCID: PMC2701248.
    81. Pugach MK, Strother J, Darling CL, Fried D, Gansky SA, Marshall SJ, Marshall GW. Dentin caries zones: mineral, structure, and properties. J Dent Res. 2009 Jan; 88(1):71-6. PMID: 19131321; PMCID: PMC2759645.
    82. Lee D, Fried D, Darling CL. Near-IR Multi-modal Imaging of Natural Occlusal Lesions. Proc SPIE Int Soc Opt Eng. 2009; 7162:71620X. PMID: 22228979.
      View in: PubMed
    83. Manesh SK, Darling CL, Fried D. Assessment of Dentin Remineralization with PS-OCT. Proc SPIE Int Soc Opt Eng. 2009 Jan 1; 7162. PMID: 21998493.
      View in: PubMed
    84. Staninec M, Meshkin N, Manesh SK, Ritchie RO, Fried D. Weakening of dentin from cracks resulting from laser irradiation. Dent Mater. 2009 Apr; 25(4):520-5. PMID: 19062088; PMCID: PMC3195403.
    85. Hsu DJ, Darling CL, Lachica MM, Fried D. Nondestructive assessment of the inhibition of enamel demineralization by CO2 laser treatment using polarization sensitive optical coherence tomography. J Biomed Opt. 2008 Sep-Oct; 13(5):054027. PMID: 19021407.
      View in: PubMed
    86. Can AM, Darling CL, Ho C, Fried D. Non-destructive assessment of inhibition of demineralization in dental enamel irradiated by a lambda=9.3-microm CO2 laser at ablative irradiation intensities with PS-OCT. Lasers Surg Med. 2008 Jul; 40(5):342-9. PMID: 18563781.
      View in: PubMed
    87. Hirasuna K, Fried D, Darling CL. Near-infrared imaging of developmental defects in dental enamel. J Biomed Opt. 2008 Jul-Aug; 13(4):044011. PMID: 19021339.
      View in: PubMed
    88. Can AM, Darling CL, Fried D. High-resolution PS-OCT of Enamel Remineralization. Proc SPIE Int Soc Opt Eng. 2008 Mar; 6843:68430T1-68430T7. PMID: 21909226.
      View in: PubMed
    89. Hsu DJ, Darling CL, Fried D. Imaging laser irradiated enamel surfaces with polarization sensitive optical coherence tomography. Proc SPIE Int Soc Opt Eng. 2008 Mar; 6843:8430N-N8430. PMID: 21909224.
      View in: PubMed
    90. Tao YC, Fried D. Selective Removal of Natural Occlusal Caries by Coupling Near-infrared Imaging with a CO(2) Laser. Proc SPIE Int Soc Opt Eng. 2008 Mar; 6843:68430I-68430I8. PMID: 21909225.
      View in: PubMed
    91. Darling CL, Fried D. Real-time near IR (1310 nm) imaging of CO2 laser ablation of enamel. Opt Express. 2008 Feb 18; 16(4):2685-93. PMID: 18542353.
      View in: PubMed
    92. Darling CL, Maffei ME, Fried WA, Fried D. Near-IR imaging of Erbium Laser Ablation with a Water Spray. Proc SPIE Int Soc Opt Eng. 2008 Jan 20; 6843(684303). PMID: 21892255.
      View in: PubMed
    93. Manesh SK, Darling CL, Fried D. Imaging natural and artificial demineralization on dentin surfaces with polarization sensitive optical coherence tomography. Proc SPIE Int Soc Opt Eng. 2008 Jan 1; 6843. PMID: 21998492.
      View in: PubMed
    94. Assa S, Meyer S, Fried D. Ablation of Dental Hard Tissues with a Microsecond Pulsed Carbon Dioxide Laser Operating at 9.3-µm with an Integrated Scanner. Proc SPIE Int Soc Opt Eng. 2008; 6843:684308. PMID: 22228978.
      View in: PubMed
    95. Chong SL, Darling CL, Fried D. Nondestructive measurement of the inhibition of demineralization on smooth surfaces using polarization-sensitive optical coherence tomography. Lasers Surg Med. 2007 Jun; 39(5):422-7. PMID: 17565731.
      View in: PubMed
    96. Tao YC, Fan K, Fried D. Near-infrared image-guided laser ablation of artificial caries lesions. Proc SPIE Int Soc Opt Eng. 2007; 6425:64250T. PMID: 22866210.
      View in: PubMed
    97. Fan K, Bell P, Fried D. Rapid and conservative ablation and modification of enamel, dentin, and alveolar bone using a high repetition rate transverse excited atmospheric pressure CO2 laser operating at lambda=9.3 micro. J Biomed Opt. 2006 Nov-Dec; 11(6):064008. PMID: 17212531.
      View in: PubMed
    98. Fried D, Featherstone JD, Le CQ, Fan K. Dissolution studies of bovine dental enamel surfaces modified by high-speed scanning ablation with a lambda = 9.3-microm TEA CO(2) laser. Lasers Surg Med. 2006 Oct; 38(9):837-45. PMID: 17044095.
      View in: PubMed
    99. Staninec M, Gardner AK, Le CQ, Sarma AV, Fried D. Adhesion of composite to enamel and dentin surfaces irradiated by IR laser pulses of 0.5-35 micros duration. J Biomed Mater Res B Appl Biomater. 2006 Oct; 79(1):193-201. PMID: 16637032.
      View in: PubMed
    100. Jones RS, Fried D. Remineralization of enamel caries can decrease optical reflectivity. J Dent Res. 2006 Sep; 85(9):804-8. PMID: 16931861; PMCID: PMC2254215.
    101. Darling CL, Huynh GD, Fried D. Light scattering properties of natural and artificially demineralized dental enamel at 1310 nm. J Biomed Opt. 2006 May-Jun; 11(3):34023. PMID: 16822072.
      View in: PubMed
    102. Jones RS, Darling CL, Featherstone JD, Fried D. Imaging artificial caries on the occlusal surfaces with polarization-sensitive optical coherence tomography. Caries Res. 2006; 40(2):81-9. PMID: 16508263.
      View in: PubMed
    103. Jones RS, Darling CL, Featherstone JD, Fried D. Remineralization of in vitro dental caries assessed with polarization-sensitive optical coherence tomography. J Biomed Opt. 2006 Jan-Feb; 11(1):014016. PMID: 16526893.
      View in: PubMed
    104. Fried D, Featherstone JD, Darling CL, Jones RS, Ngaotheppitak P, Bühler CM. Early caries imaging and monitoring with near-infrared light. Dent Clin North Am. 2005 Oct; 49(4):771-93, vi. PMID: 16150316.
      View in: PubMed
    105. Ngaotheppitak P, Darling CL, Fried D. Measurement of the severity of natural smooth surface (interproximal) caries lesions with polarization sensitive optical coherence tomography. Lasers Surg Med. 2005 Jul; 37(1):78-88. PMID: 15889402.
      View in: PubMed
    106. Bühler C, Ngaotheppitak P, Fried D. Imaging of occlusal dental caries (decay) with near-IR light at 1310-nm. Opt Express. 2005 Jan 24; 13(2):573-82. PMID: 19488387.
      View in: PubMed
    107. Louie TM, Jones RS, Sarma AV, Fried D. Selective removal of composite sealants with near-ultraviolet laser pulses of nanosecond duration. J Biomed Opt. 2005 Jan-Feb; 10(1):14001. PMID: 15847582.
      View in: PubMed
    108. Fried NM, Yang Y, Chaney CA, Fried D. Transmission of Q-switched erbium:YSGG (lambda=2.79 microm) and erbium:YAG (lambda=2.94 microm) laser radiation through germanium oxide and sapphire optical fibres at high pulse energies. Lasers Med Sci. 2004; 19(3):155-60. PMID: 15645320.
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    109. Jones RS, Staninec M, Fried D. Imaging artificial caries under composite sealants and restorations. J Biomed Opt. 2004 Nov-Dec; 9(6):1297-304. PMID: 15568951.
      View in: PubMed
    110. Sheth KK, Staninec M, Sarma AV, Fried D. Selective targeting of protein, water, and mineral in dentin using UV and IR pulse lasers: the effect on the bond strength to composite restorative materials. Lasers Surg Med. 2004; 35(4):245-53. PMID: 15493023.
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    111. Dela Rosa A, Sarma AV, Le CQ, Jones RS, Fried D. Peripheral thermal and mechanical damage to dentin with microsecond and sub-microsecond 9.6 microm, 2.79 microm, and 0.355 microm laser pulses. Lasers Surg Med. 2004; 35(3):214-28. PMID: 15389737.
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    112. Goodis HE, Fried D, Gansky S, Rechmann P, Featherstone JD. Pulpal safety of 9.6 microm TEA CO2 laser used for caries prevention. Lasers Surg Med. 2004; 35(2):104-10. PMID: 15334612.
      View in: PubMed
    113. Jones R, Huynh G, Jones G, Fried D. Near-infrared transillumination at 1310-nm for the imaging of early dental decay. Opt Express. 2003 Sep 8; 11(18):2259-65. PMID: 19466117.
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    114. Wheeler CR, Fried D, Featherstone JD, Watanabe LG, Le CQ. Irradiation of dental enamel with Q-switched lambda = 355-nm laser pulses: surface morphology, fluoride adsorption, and adhesion to composite resin. Lasers Surg Med. 2003; 32(4):310-7. PMID: 12696100.
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    115. Staninec M, Xie J, Le CQ, Fried D. Influence of an optically thick water layer on the bond-strength of composite resin to dental enamel after IR laser ablation. Lasers Surg Med. 2003; 33(4):264-9. PMID: 14571452.
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    116. Fried D, Xie J, Shafi S, Featherstone JD, Breunig TM, Le C. Imaging caries lesions and lesion progression with polarization sensitive optical coherence tomography. J Biomed Opt. 2002 Oct; 7(4):618-27. PMID: 12421130.
      View in: PubMed
    117. Fried D, Ashouri N, Breunig T, Shori R. Mechanism of water augmentation during IR laser ablation of dental enamel. Lasers Surg Med. 2002; 31(3):186-93. PMID: 12224092.
      View in: PubMed
    118. Alexander R, Xie J, Fried D. Selective removal of residual composite from dental enamel surfaces using the third harmonic of a Q-switched Nd:YAG laser. Lasers Surg Med. 2002; 30(3):240-5. PMID: 11891745.
      View in: PubMed
    119. Fried D, Zuerlein MJ, Le CQ, Featherstone JD. Thermal and chemical modification of dentin by 9-11-microm CO2 laser pulses of 5-100-micros duration. Lasers Surg Med. 2002; 31(4):275-82. PMID: 12355574.
      View in: PubMed
    120. Harris DM, White JM, Goodis H, Arcoria CJ, Simon J, Carpenter WM, Fried D, Burkart J, Yessik M, Myers T. Selective ablation of surface enamel caries with a pulsed Nd:YAG dental laser. Lasers Surg Med. 2002; 30(5):342-50. PMID: 12116326.
      View in: PubMed
    121. Fried D, Ragadio J, Akrivou M, Featherstone JD, Murray MW, Dickenson KM. Dental hard tissue modification and removal using sealed transverse excited atmospheric-pressure lasers operating at lambda=9.6 and 10.6 microm. J Biomed Opt. 2001 Apr; 6(2):231-8. PMID: 11375734.
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    122. Fried D, Ragadio J, Champion A. Residual heat deposition in dental enamel during IR laser ablation at 2.79, 2.94, 9.6, and 10.6 microm. Lasers Surg Med. 2001; 29(3):221-9. PMID: 11573223.
      View in: PubMed
    123. Dumore T, Fried D. Selective ablation of orthodontic composite by using sub-microsecond IR laser pulses with optical feedback. Lasers Surg Med. 2000; 27(2):103-10. PMID: 10960816.
      View in: PubMed
    124. Zuerlein MJ, Fried D, Featherstone JD. Modeling the modification depth of carbon dioxide laser-treated dental enamel. Lasers Surg Med. 1999; 25(4):335-47. PMID: 10534750.
      View in: PubMed
    125. Featherstone JD, Barrett-Vespone NA, Fried D, Kantorowitz Z, Seka W. CO2 laser inhibitor of artificial caries-like lesion progression in dental enamel. J Dent Res. 1998 Jun; 77(6):1397-403. PMID: 9649168.
      View in: PubMed
    126. Fried D, Glena RE, Featherstone JD, Seka W. Permanent and transient changes in the reflectance of CO2 laser-irradiated dental hard tissues at lambda = 9.3, 9.6, 10.3, and 10.6 microns and at fluences of 1-20 J/cm2. Lasers Surg Med. 1997; 20(1):22-31. PMID: 9041504.
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