Yihua Zhu, PhD

Title(s)Specialist, Radiology
SchoolSchool of Medicine
Address185 Berry Street Bldg B, #396-7
San Francisco CA 94107
PronounsHe/Him/His
ORCID ORCID Icon0009-0006-8054-8261 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California San Francisco, San Francisco, CAPHD06/2024Oral and Craniofacial Sciences
    University of Pennsylvania, Philadelphia, PAMS12/2018Medical Physics
    University of Southern California, Los Angeles, CABA06/2016Physics

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    Collapse Overview
    Yihua Zhu is a research specialist at the Bone Quality Research Lab in the Department of Radiology and Biomedical Imaging at UCSF, led by Dr. Galateia Kazakia. His work focuses on advanced image processing and analysis techniques, specifically in high-resolution peripheral quantitative computed tomography (HR-pQCT), dual-energy X-ray absorptiometry (DXA), and magnetic resonance imaging (MRI) for bone quality assessment.

    Yihua earned his Ph.D. from UCSF in May 2024, where he specialized in optical imaging applications in dentistry. His doctoral research included developing a pioneering dual-wavelength short-wave infrared (SWIR) intraoral camera for early caries detection, featured in multiple NIH-funded clinical studies. Additionally, he explored optical coherence tomography (OCT) for monitoring remineralization in dental lesions and applied machine learning to enhance fluorescence-guided intraoperative therapy.

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. In vitro Assessment of lesion activity using simultaneous time-resolved reflectance imaging at 1300 and 1950 nm. Lasers Med Sci. 2024 Aug 27; 39(1):223. Wycoff S, Zhu Y, Fried D. PMID: 39191998.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Clinical SWIR and CP-OCT imaging of interproximal lesions. BMC Oral Health. 2024 Aug 17; 24(1):959. Zhu Y, Le O, Xue J, Wycoff S, Fried D. PMID: 39153971; PMCID: PMC11330057.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Short-Wavelength Infrared Imaging of Infected and Affected Dentin. Diagnostics (Basel). 2024 Mar 30; 14(7). Ng M, Ho YC, Wycoff S, Zhu Y, Fried D. PMID: 38611657; PMCID: PMC11012186.
      View in: PubMed   Mentions: 1  
    4. Diagnostic Performance of Multispectral SWIR Transillumination and Reflectance Imaging for Caries Detection. Diagnostics (Basel). 2023 Aug 31; 13(17). Zhu Y, Ng C, Le O, Ho YC, Fried D. PMID: 37685362; PMCID: PMC10487234.
      View in: PubMed   Mentions: 2  
    5. Time-resolved SWIR imaging for the assessment of the activity of occlusal caries lesions. J Biophotonics. 2023 10; 16(10):e202300165. Ng M, Wycoff S, Zhu Y, Ho YC, Takasuka H, Fried D. PMID: 37316468; PMCID: PMC10846334.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Monitoring lesion activity on primary teeth with CP-OCT and SWIR reflectance imaging. Lasers Surg Med. 2023 08; 55(6):601-609. Zhu Y, Kim J, Lin B, Fried D. PMID: 37172310.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    7. Active Surveillance of Root Caries in Vivo with CP-OCT. Diagnostics (Basel). 2023 Jan 27; 13(3). Zhu Y, Kim M, Curtis D, Wang J, Le O, Fried D. PMID: 36766570; PMCID: PMC9914565.
      View in: PubMed   Mentions:
    8. Assessment of the activity of secondary caries lesions with short-wavelength infrared, thermal, and optical coherence tomographic imaging. J Biomed Opt. 2023 09; 28(9):094801. Chang NN, Dillas T, Zhu Y, Fried D. PMID: 36761935; PMCID: PMC9830003.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Evaluating interproximal and occlusal lesion severity with a dual SWIR transillumination/reflectance probe. Proc SPIE Int Soc Opt Eng. 2022 Jan-Feb; 11942. Zhu Y, Fried D. PMID: 35444360; PMCID: PMC9017391.
      View in: PubMed   Mentions: 1  
    10. Measurement of the Depth of Lesions on Proximal Surfaces with SWIR Multispectral Transillumination and Reflectance Imaging. Diagnostics (Basel). 2022 Feb 26; 12(3). Zhu Y, Fried D. PMID: 35328150; PMCID: PMC8947190.
      View in: PubMed   Mentions: 3  
    11. Compact in vivo handheld dual SWIR transillumination/reflectance imaging system for the detection of proximal and occlusal lesions. Proc SPIE Int Soc Opt Eng. 2021 Mar; 11627. Zhu Y, Simon J, Ng C, Fried D. PMID: 33790493; PMCID: PMC8008980.
      View in: PubMed   Mentions: 1  
    12. Dual short wavelength infrared transillumination/reflectance mode imaging for caries detection. J Biomed Opt. 2021 01; 26(4). Zhu Y, Abdelaziz M, Simon J, Le O, Fried D. PMID: 33515220; PMCID: PMC7844424.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    13. A dual handheld SWIR transillumination/reflectance probe for imaging lesions on tooth occlusal and proximal surfaces. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Zhu Y, Chang NY, Fried WA, Yang V, Fried D. PMID: 33603261; PMCID: PMC7888982.
      View in: PubMed   Mentions: 4  
    14. SWIR, Thermal and CP-OCT imaging probes for the in vivo assessment of the activity of root caries lesions. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Chang NY, Zhu Y, Curtis D, Le O, Yang V, Fried WA, Simon JC, Banan P, Darling CL, Fried D. PMID: 33612912; PMCID: PMC7894617.
      View in: PubMed   Mentions: 2  
    15. A SWIR imaging handpiece for the clinical assessment of lesion activity via dehydration. Preclinical Assessment. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Fried WA, Zhu Y, Yang V, Chang NY, Fried D. PMID: 32194294; PMCID: PMC7081727.
      View in: PubMed   Mentions: 1  
    16. Cherenkov imaging for total skin electron therapy (TSET). Med Phys. 2020 Jan; 47(1):201-212. Xie Y, Petroccia H, Maity A, Miao T, Zhu Y, Bruza P, Pogue BW, Plastaras JP, Dong L, Zhu TC. PMID: 31665544; PMCID: PMC7050296.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    17. Validation of tissue optical properties measurement using diffuse reflectance spectroscopy (DRS). Proc SPIE Int Soc Opt Eng. 2019 Feb; 10860. Ong YH, Zhu Y, Zhu TC. PMID: 31057197; PMCID: PMC6497391.
      View in: PubMed   Mentions: 6  
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