Daniel Fried, PhD

Title(s)Professor, Preventive & Restor Dent Sci
SchoolSchool of Dentistry
Address707 Parnassus Avenue, #2234
San Francisco CA 94143
Phone415-502-6641
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    Collapse Research 
    Collapse Research Activities and Funding
    Imaging Dental Caries with SWIR Light
    NIH R01DE028295Aug 1, 2019 - Apr 30, 2024
    Role: Principal Investigator
    Optical Methods for Lesion Activity Assessment
    NIH R01DE027335Sep 1, 2018 - Jun 30, 2023
    Role: Principal Investigator
    Selective Ablation of Dental Caries and Composites
    NIH R01DE019631Sep 1, 2009 - Mar 31, 2019
    Role: Principal Investigator
    Clinical Assessment of Tooth Demineralization & Remineralization with PS-OCT
    NIH R01DE017869Aug 15, 2006 - Jul 31, 2016
    Role: Principal Investigator
    Early Caries Detection with Near-IR Light
    NIH R01DE014698Aug 1, 2002 - Apr 30, 2018
    Role: Principal Investigator
    Laser Ablation of Dental Hard Tissues
    NIH R01DE014554Jun 1, 2002 - May 31, 2008
    Role: Principal Investigator
    MULTIPURPOSE CO2 TEA LASER FOR DENTAL APPLICATIONS
    NIH R41DE012971Aug 1, 2000 - Jul 31, 2001
    Role: Principal Investigator
    IR LASER ABLATION OF DENTAL HARD TISSUE
    NIH R29DE012091Aug 1, 1997 - May 31, 2003
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. In vitro Assessment of lesion activity using simultaneous time-resolved reflectance imaging at 1300 and 1950 nm. Lasers Med Sci. 2024 Aug 27; 39(1):223. Wycoff S, Zhu Y, Fried D. PMID: 39191998.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Clinical SWIR and CP-OCT imaging of interproximal lesions. BMC Oral Health. 2024 Aug 17; 24(1):959. Zhu Y, Le O, Xue J, Wycoff S, Fried D. PMID: 39153971; PMCID: PMC11330057.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Short-Wavelength Infrared Imaging of Infected and Affected Dentin. Diagnostics (Basel). 2024 Mar 30; 14(7). Ng M, Ho YC, Wycoff S, Zhu Y, Fried D. PMID: 38611657; PMCID: PMC11012186.
      View in: PubMed   Mentions: 1  
    4. Special Section Guest Editorial: Short Wave Infrared Techniques and Applications in Biomedical Optics. J Biomed Opt. 2023 09; 28(9):094800. Fried D, Pierce M, Roblyer D. PMID: 37692561; PMCID: PMC10492591.
      View in: PubMed   Mentions:    Fields:    
    5. Longitudinal assessment of dental erosion-abrasion by cross-polarization optical coherence tomography in vitro. Braz Oral Res. 2023; 37:e081. Romero MJR, Bezerra SJC, Fried D, Lippert F, Eckert GJ, Hara AT. PMID: 37672415.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Diagnostic Performance of Multispectral SWIR Transillumination and Reflectance Imaging for Caries Detection. Diagnostics (Basel). 2023 Aug 31; 13(17). Zhu Y, Ng C, Le O, Ho YC, Fried D. PMID: 37685362; PMCID: PMC10487234.
      View in: PubMed   Mentions: 2  
    7. Exploratory Analysis of Objective Outcome Measures for the Clinical Assessment of Erosive Tooth Wear. Diagnostics (Basel). 2023 Aug 02; 13(15). Romero MJRH, Ungar PS, Fried D, Lippert F, Zero DT, Zunt S, Eckert GJ, Gossweiler AG, Elkington-Stauss DJ, Tamayo-Cabeza G, Kelly AB, Bartels T, Kita C, Wewers E, Hara AT. PMID: 37568931; PMCID: PMC10417370.
      View in: PubMed   Mentions:
    8. Time-resolved SWIR imaging for the assessment of the activity of occlusal caries lesions. J Biophotonics. 2023 10; 16(10):e202300165. Ng M, Wycoff S, Zhu Y, Ho YC, Takasuka H, Fried D. PMID: 37316468; PMCID: PMC10846334.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Monitoring lesion activity on primary teeth with CP-OCT and SWIR reflectance imaging. Lasers Surg Med. 2023 08; 55(6):601-609. Zhu Y, Kim J, Lin B, Fried D. PMID: 37172310.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Active Surveillance of Root Caries in Vivo with CP-OCT. Diagnostics (Basel). 2023 Jan 27; 13(3). Zhu Y, Kim M, Curtis D, Wang J, Le O, Fried D. PMID: 36766570; PMCID: PMC9914565.
      View in: PubMed   Mentions:
    11. Assessment of the activity of secondary caries lesions with short-wavelength infrared, thermal, and optical coherence tomographic imaging. J Biomed Opt. 2023 09; 28(9):094801. Chang NN, Dillas T, Zhu Y, Fried D. PMID: 36761935; PMCID: PMC9830003.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Caries inhibition of simulated active caries lesions with CO2 laser irradiation and fluoride. Proc SPIE Int Soc Opt Eng. 2022 Jan-Feb; 11942. Tressel J, Kashirtsev F, Cheung K, Simon J, Fried D. PMID: 35450400; PMCID: PMC9020385.
      View in: PubMed   Mentions:
    13. Assessing lesion activity of secondary lesions on extracted teeth by thermal dehydration measurement and optical coherence tomography. Proc SPIE Int Soc Opt Eng. 2022 Jan-Feb; 11942. Chang NN, Dillas T, Fried D. PMID: 35450401; PMCID: PMC9020384.
      View in: PubMed   Mentions: 1  
    14. Dehydration imaging of dental fluorosis at 1950 nm. Proc SPIE Int Soc Opt Eng. 2022 Jan-Feb; 11942. Kashirtsev F, Tressel J, Fried D. PMID: 35440838; PMCID: PMC9014758.
      View in: PubMed   Mentions: 1  
    15. Evaluating interproximal and occlusal lesion severity with a dual SWIR transillumination/reflectance probe. Proc SPIE Int Soc Opt Eng. 2022 Jan-Feb; 11942. Zhu Y, Fried D. PMID: 35444360; PMCID: PMC9017391.
      View in: PubMed   Mentions: 1  
    16. Use of SWIR dehydration and OCT to assess the complete arrest of simulated incipient caries lesions. Proc SPIE Int Soc Opt Eng. 2022 Jan-Feb; 11942. Chang NY, Tressel J, Kashirtsev F, Fried D. PMID: 35444361; PMCID: PMC9017390.
      View in: PubMed   Mentions:
    17. Measurement of the Depth of Lesions on Proximal Surfaces with SWIR Multispectral Transillumination and Reflectance Imaging. Diagnostics (Basel). 2022 Feb 26; 12(3). Zhu Y, Fried D. PMID: 35328150; PMCID: PMC8947190.
      View in: PubMed   Mentions: 3  
    18. Monitoring silver diamine fluoride application with optical coherence tomography and thermal imaging: An in vitro proof of concept study. Lasers Surg Med. 2022 07; 54(5):790-803. Abdelaziz M, Yang V, Chang NN, Darling C, Fried W, Seto J, Fried D. PMID: 35212407; PMCID: PMC9189075.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    19. High contrast imaging of dental fluorosis in the short wavelength infrared. J Biophotonics. 2021 10; 14(10):e202100145. Kashirtsev F, Tressel J, Simon JC, Fried D. PMID: 34302430; PMCID: PMC9380435.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    20. Cross-polarization optical coherence tomographic assessment of in situ simulated erosive tooth wear. J Biophotonics. 2021 09; 14(9):e202100090. Romero MJRH, Bezerra SJC, Fried D, Yang V, Lippert F, Eckert GJ, Zero DT, Hara AT. PMID: 34105881; PMCID: PMC8448929.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Computer-Controlled CO2 Laser Ablation System for Cone-beam Computed Tomography and Digital Image Guided Endodontic Access: A Pilot Study. J Endod. 2021 Sep; 47(9):1445-1452. Simon JC, Kwok JW, Vinculado F, Fried D. PMID: 34119563; PMCID: PMC8867881.
      View in: PubMed   Mentions: 4     Fields:    
    22. Dynamic SWIR imaging near the 1950-nm water absorption band for caries lesion diagnosis. J Biomed Opt. 2021 05; 26(5). Tressel JT, Abdelaziz M, Fried D. PMID: 34032036; PMCID: PMC8144227.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    23. Imaging dental fluorosis at SWIR wavelengths from 1300 to 2000-nm. Proc SPIE Int Soc Opt Eng. 2021 Mar; 11627. Kashirtsev F, Simon JC, Fried D. PMID: 33767522; PMCID: PMC7989784.
      View in: PubMed   Mentions: 2  
    24. High contrast reflectance imaging at 1950 nm for the assessment of lesion activity on extracted teeth. Proc SPIE Int Soc Opt Eng. 2021 Mar; 11627. Tressel J, Abdelaziz M, Fried D. PMID: 33762796; PMCID: PMC7986894.
      View in: PubMed   Mentions: 3  
    25. Infrared imaging confirms the role of the transparent surface zone in arresting dental caries. Proc SPIE Int Soc Opt Eng. 2021 Mar; 11627. Liu H, Chang NY, Gao W, Fried D. PMID: 33767521; PMCID: PMC7989780.
      View in: PubMed   Mentions: 3  
    26. Multispectral SWIR images of the pulp-chamber of posterior teeth in vitro. Proc SPIE Int Soc Opt Eng. 2021 Mar; 11627. Simon JC, Mogire EO, Yun SY, Fried D. PMID: 33776188; PMCID: PMC7993031.
      View in: PubMed   Mentions: 1  
    27. Compact in vivo handheld dual SWIR transillumination/reflectance imaging system for the detection of proximal and occlusal lesions. Proc SPIE Int Soc Opt Eng. 2021 Mar; 11627. Zhu Y, Simon J, Ng C, Fried D. PMID: 33790493; PMCID: PMC8008980.
      View in: PubMed   Mentions: 1  
    28. High Contrast Reflectance Imaging of Enamel Demineralization and Remineralization at 1950-nm for the Assessment of Lesion Activity. Lasers Surg Med. 2021 09; 53(7):968-977. Fried WA, Abdelaziz M, Darling CL, Fried D. PMID: 33442896; PMCID: PMC8275669.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    29. Dual short wavelength infrared transillumination/reflectance mode imaging for caries detection. J Biomed Opt. 2021 01; 26(4). Zhu Y, Abdelaziz M, Simon J, Le O, Fried D. PMID: 33515220; PMCID: PMC7844424.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    30. Thermal Imaging of Root Caries In Vivo. J Dent Res. 2020 12; 99(13):1502-1508. Yang V, Zhu Y, Curtis D, Le O, Chang NYN, Fried WA, Simon JC, Banan P, Darling CL, Fried D. PMID: 32866422; PMCID: PMC7684841.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    31. SWIR, Thermal and CP-OCT imaging probes for the in vivo assessment of the activity of root caries lesions. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Chang NY, Zhu Y, Curtis D, Le O, Yang V, Fried WA, Simon JC, Banan P, Darling CL, Fried D. PMID: 33612912; PMCID: PMC7894617.
      View in: PubMed   Mentions: 2  
    32. A SWIR imaging handpiece for the clinical assessment of lesion activity via dehydration. Preclinical Assessment. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Fried WA, Zhu Y, Yang V, Chang NY, Fried D. PMID: 32194294; PMCID: PMC7081727.
      View in: PubMed   Mentions: 1  
    33. Optical Coherence Tomography (OCT) for the evaluation of internal adaptation of class V resin restorations on Dentin. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Abdelaziz M, Zuluaga AF, Betancourt F, Fried D, Krejci I, Bortolotto T. PMID: 33603262; PMCID: PMC7888983.
      View in: PubMed   Mentions: 2  
    34. A dual handheld SWIR transillumination/reflectance probe for imaging lesions on tooth occlusal and proximal surfaces. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Zhu Y, Chang NY, Fried WA, Yang V, Fried D. PMID: 33603261; PMCID: PMC7888982.
      View in: PubMed   Mentions: 4  
    35. In vivo spectral guided removal of composite from tooth surfaces with a CO2 laser. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Simon JC, Choi JH, Jang A, Fried D. PMID: 32161428; PMCID: PMC7065526.
      View in: PubMed   Mentions: 1  
    36. A thermal imaging handpiece for the clinical assessment of lesion activity on root surfaces via dehydration. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Yang VB, Chang NY, Fried D. PMID: 32231402; PMCID: PMC7105143.
      View in: PubMed   Mentions: 2  
    37. Enhancing the detection of proximal cavities on near infrared transillumination images with Indocyanine Green (ICG) as a contrast medium: In vitro proof of concept studies. J Dent. 2019 12; 91:103222. Abdelaziz M, Krejci I, Fried D. PMID: 31682898; PMCID: PMC6885130.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    38. Measurement of the shrinkage of natural and simulated lesions on root surfaces using CP-OCT. J Dent. 2019 11; 90:103213. Yang V, Fried D. PMID: 31622647; PMCID: PMC6905190.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    39. In vitro longitudinal evaluation of enamel wear by cross-polarization optical coherence tomography. Dent Mater. 2019 10; 35(10):1464-1470. Alghilan MA, Lippert F, Platt JA, Eckert GJ, González-Cabezas C, Fried D, Hara AT. PMID: 31395451.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    40. Image-Guided Ablation of Dental Calculus From Root Surfaces Using a DPSS Er:YAG Laser. Lasers Surg Med. 2020 03; 52(3):247-258. Fried WA, Chan KH, Darling CL, Curtis DA, Fried D. PMID: 31236996; PMCID: PMC8880256.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    41. Near-infrared imaging of demineralization on the occlusal surfaces of teeth without the interference of stains. J Biomed Opt. 2019 03; 24(3):1-8. Ng C, Almaz E, Simon J, Fried D, Darling C. PMID: 30834721; PMCID: PMC6975183.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    42. Image guided laser ablation of demineralization from root surfaces. Proc SPIE Int Soc Opt Eng. 2019 Feb; 10857. Dhillon N, Chan KH, Yang VB, Fried D. PMID: 31007338; PMCID: PMC6469870.
      View in: PubMed   Mentions:
    43. Selective removal of dental calculus with a diode-pumped Er:YAG laser. Proc SPIE Int Soc Opt Eng. 2019 Feb; 10857. Fried WA, Chan KH, Darling CL, Fried D. PMID: 31000908; PMCID: PMC6467515.
      View in: PubMed   Mentions: 1  
    44. The contrast of demineralization on tooth occlusal surfaces from 405 to 1950-nm with varying depth. Proc SPIE Int Soc Opt Eng. 2019 Feb; 10857. Mohajerani N, Chan KH, Yang VB, Fried D, Darling CL. PMID: 30923417; PMCID: PMC6434518.
      View in: PubMed   Mentions:
    45. The Relationship of Dehydration Rate and Transparent Surface Layer Thickness for Coronal Lesions on Extracted Teeth. Proc SPIE Int Soc Opt Eng. 2019 Feb; 10857. Chang NN, Abdelaziz M, Fried D. PMID: 30918416; PMCID: PMC6433154.
      View in: PubMed   Mentions: 1  
    46. An appliance for monitoring the shrinkage of root caries with OCT. Proc SPIE Int Soc Opt Eng. 2019 Feb; 10857. Yang VB, Fried D. PMID: 30918417; PMCID: PMC6433155.
      View in: PubMed   Mentions: 1  
    47. Impact of surface micromorphology and demineralization severity on enamel loss measurements by cross-polarization optical coherence tomography. J Dent. 2019 02; 81:52-58. Alghilan MA, Lippert F, Platt JA, Eckert GJ, González-Cabezas C, Fried D, Hara AT. PMID: 30582963.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    48. Use of a DPSS Er:YAG laser for the selective removal of composite from tooth surfaces. Biomed Opt Express. 2018 Oct 01; 9(10):5026-5036. Fried WA, Chan KH, Darling CL, Fried D. PMID: 30319919; PMCID: PMC6179409.
      View in: PubMed   Mentions: 7  
    49. Selective ablation of dental caries using coaxial Co2 (9.3-μm) and near-IR (1880-nm) lasers. Lasers Surg Med. 2019 02; 51(2):176-184. Chan KH, Fried D. PMID: 30024032; PMCID: PMC8867882.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    50. Cross-polarization reflectance imaging of root caries and dental calculus on extracted teeth at wavelengths from 400 to 2350 nm. J Biophotonics. 2018 11; 11(11):e201800113. Yang VB, Curtis DA, Fried D. PMID: 29952066.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    51. Fluorescence and Near-Infrared Light Transillumination. Dent Clin North Am. 2018 Jul; 62(3):435-452. Amaechi BT, Owosho AA, Fried D. PMID: 29903560.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    52. Optical Coherence Tomography. Dent Clin North Am. 2018 Jul; 62(3):421-434. Katkar RA, Tadinada SA, Amaechi BT, Fried D. PMID: 29903559.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    53. Multispectral cross-polarization reflectance measurements suggest high contrast of demineralization on tooth surfaces at wavelengths beyond 1300 nm due to reduced light scattering in sound enamel. J Biomed Opt. 2018 06; 23(6):1-4. Chan KH, Fried D. PMID: 29877068; PMCID: PMC5989821.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    54. Multispectral near-infrared reflectance and transillumination imaging of occlusal carious lesions: Variation in lesion contrast with lesion depth. Proc SPIE Int Soc Opt Eng. 2018 Jan-Feb; 10473. Simon JC, Curtis DA, Darling CL, Fried D. PMID: 29497229; PMCID: PMC5827960.
      View in: PubMed   Mentions: 7  
    55. Image-guided Removal of Interproximal Lesions with a CO2 Laser. Proc SPIE Int Soc Opt Eng. 2018 Jan-Feb; 10473. Ngo A, Chan KH, Le O, Simon JC, Fried D. PMID: 29497230; PMCID: PMC5827963.
      View in: PubMed   Mentions: 2  
    56. SWIR reflectance imaging of demineralization on the occlusal surfaces of teeth beyond 1700 nm. Proc SPIE Int Soc Opt Eng. 2018 Jan-Feb; 10473. Ng C, Simon JC, Fried D, Darling CL. PMID: 30686852; PMCID: PMC6345412.
      View in: PubMed   Mentions: 2  
    57. Lesion Dehydration Rate Changes with the Surface Layer Thickness during Enamel Remineralization. Proc SPIE Int Soc Opt Eng. 2018 Feb; 10473. Chang NN, Jew JM, Fried D. PMID: 30034077; PMCID: PMC6053078.
      View in: PubMed   Mentions: 8  
    58. Selective Ablation of Carious Lesions using an Integrated Near-IR Imaging System and a Novel 9.3-µm CO2 Laser. Proc SPIE Int Soc Opt Eng. 2018 Feb; 10473. Chan KH, Fried NM, Fried D. PMID: 30034078; PMCID: PMC6054456.
      View in: PubMed   Mentions: 5  
    59. Influence of multi-wavelength laser irradiation of enamel and dentin surfaces at 0.355, 2.94, and 9.4 μm on surface morphology, permeability, and acid resistance. Lasers Surg Med. 2017 12; 49(10):913-927. Chang NN, Jew JM, Simon JC, Chen KH, Lee RC, Fried WA, Cho J, Darling CL, Fried D. PMID: 28699676; PMCID: PMC5734993.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    60. Automated ablation of dental composite using an IR pulsed laser coupled to a plume emission spectral feedback system. Lasers Surg Med. 2017 09; 49(7):658-665. Jang AT, Chan KH, Fried D. PMID: 28467687; PMCID: PMC5568963.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    61. Near-IR and CP-OCT imaging of suspected occlusal caries lesions. Lasers Surg Med. 2017 03; 49(3):215-224. Simon JC, Kang H, Staninec M, Jang AT, Chan KH, Darling CL, Lee RC, Fried D. PMID: 28339115; PMCID: PMC5367963.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    62. Influence of a pulsed CO2 laser operating at 9.4  μm on the surface morphology, reflectivity, and acid resistance of dental enamel below the threshold for melting. J Biomed Opt. 2017 02 01; 22(2):28001. Kim JW, Lee R, Chan KH, Jew JM, Fried D. PMID: 28145558; PMCID: PMC5286555.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    63. Optical changes of dentin in the near-IR as a function of mineral content. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Berg RA, Simon JC, Fried D, Darling CL. PMID: 28450756; PMCID: PMC5404412.
      View in: PubMed   Mentions: 1  
    64. Assessment of radicular dentin permeability after irradiation with CO2 laser and endodontic irrigation treatments with thermal imaging. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Cho H, Lee RC, Chan KH, Fried D. PMID: 28626288; PMCID: PMC5473517.
      View in: PubMed   Mentions:
    65. Assessment of cavitation in artificial approximal dental lesions with near-IR imaging. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Simon JC, Darling CL, Fried D. PMID: 28626283; PMCID: PMC5473505.
      View in: PubMed   Mentions: 7  
    66. Selective Laser Ablation of Carious Lesions using Simultaneous Scanned Near-IR Diode and CO2 Lasers. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Chan KH, Fried D. PMID: 28626285; PMCID: PMC5473510.
      View in: PubMed   Mentions: 1  
    67. Near-infrared imaging of enamel hypomineralization due to developmental defects. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Lee RC, Jang A, Fried D. PMID: 28626284; PMCID: PMC5473506.
      View in: PubMed   Mentions: 4  
    68. Synergistic effect of fluoride and laser irradiation for the inhibition of the demineralization of dental enamel. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Lee R, Chan KH, Jew J, Simon JC, Fried D. PMID: 28626286; PMCID: PMC5473511.
      View in: PubMed   Mentions: 5  
    69. Selective removal of natural caries lesions from dentin and tooth occlusal surfaces using a diode-pumped Er:YAG laser. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Jew J, Chan KH, Darling CL, Fried D. PMID: 28450757; PMCID: PMC5404413.
      View in: PubMed   Mentions: 3  
    70. Influence of Multi-Wavelength Laser Irradiation of Enamel and Dentin Surfaces on Surface Morphology and Permeability. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Chang NN, Jew J, Simon JC, Chan KH, Lee RC, Fried WA, Cho J, Darling CL, Fried D. PMID: 28680191; PMCID: PMC5495473.
      View in: PubMed   Mentions: 2  
    71. Automated ablation of dental composite using an IR pulsed laser coupled to a plume emission spectral feedback system. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Jang AT, Chan KH, Fried D. PMID: 28479654; PMCID: PMC5416812.
      View in: PubMed   Mentions:
    72. High-Contrast Reflectance Imaging of Composite Restorations Color-Matched to Tooth Structure at 1000-2300-nm. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Fried WA, Simon JC, Darling CL, Le O, Fried D. PMID: 28626287; PMCID: PMC5473514.
      View in: PubMed   Mentions: 1  
    73. Use of an optical clearing agent to enhance the visibility of subsurface structures and lesions from tooth occlusal surfaces. J Biomed Opt. 2016 Aug; 21(8):081206. Kang H, Darling CL, Fried D. PMID: 27071709; PMCID: PMC4828753.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    74. Enamel Thickness Determination by Optical Coherence Tomography: In vitro Validation. Caries Res. 2016; 50(4):400-6. Algarni A, Kang H, Fried D, Eckert GJ, Hara AT. PMID: 27454764.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    75. Near-IR transillumination and reflectance imaging at 1,300 nm and 1,500-1,700 nm for in vivo caries detection. Lasers Surg Med. 2016 11; 48(9):828-836. Simon JC, Lucas SA, Staninec M, Tom H, Chan KH, Darling CL, Cozin MJ, Lee RC, Fried D. PMID: 27389018; PMCID: PMC5495016.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    76. Activity assessment of root caries lesions with thermal and near-IR imaging methods. J Biophotonics. 2017 Mar; 10(3):433-445. Lee RC, Darling CL, Staninec M, Ragadio A, Fried D. PMID: 27060450; PMCID: PMC5053863.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    77. Infrared Methods for Assessment of the Activity of Natural Enamel Caries Lesions. IEEE J Sel Top Quantum Electron. 2016 May-Jun; 22(3). Lee RC, Staninec M, Le O, Fried D. PMID: 27642246; PMCID: PMC5021449.
      View in: PubMed   Mentions: 26  
    78. Clinical monitoring of smooth surface enamel lesions using CP-OCT during nonsurgical intervention. Lasers Surg Med. 2016 12; 48(10):915-923. Chan KH, Tom H, Lee RC, Kang H, Simon JC, Staninec M, Darling CL, Pelzner RB, Fried D. PMID: 26955902; PMCID: PMC5495013.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCTClinical Trials
    79. Assessment of remineralized dentin lesions with thermal and near-infrared reflectance imaging. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. Lee RC, Darling CL, Fried D. PMID: 27006522; PMCID: PMC4799994.
      View in: PubMed   Mentions: 6  
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    167. Near-IR imaging of Erbium Laser Ablation with a Water Spray. Proc SPIE Int Soc Opt Eng. 2008 Jan 20; 6843(684303). Darling CL, Maffei ME, Fried WA, Fried D. PMID: 21892255; PMCID: PMC3165031.
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    168. Imaging natural and artificial demineralization on dentin surfaces with polarization sensitive optical coherence tomography. Proc SPIE Int Soc Opt Eng. 2008 Jan 01; 6843. Manesh SK, Darling CL, Fried D. PMID: 21998492; PMCID: PMC3190237.
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    169. Ablation of Dental Hard Tissues with a Microsecond Pulsed Carbon Dioxide Laser Operating at 9.3-μm with an Integrated Scanner. Proc SPIE Int Soc Opt Eng. 2008; 6843:684308. Assa S, Meyer S, Fried D. PMID: 22228978; PMCID: PMC3251255.
      View in: PubMed   Mentions: 6  
    170. Nondestructive measurement of the inhibition of demineralization on smooth surfaces using polarization-sensitive optical coherence tomography. Lasers Surg Med. 2007 Jun; 39(5):422-7. Chong SL, Darling CL, Fried D. PMID: 17565731.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    171. Near-infrared image-guided laser ablation of artificial caries lesions. Proc SPIE Int Soc Opt Eng. 2007; 6425:64250T. Tao YC, Fan K, Fried D. PMID: 22866210; PMCID: PMC3409571.
      View in: PubMed   Mentions: 3  
    172. Rapid and conservative ablation and modification of enamel, dentin, and alveolar bone using a high repetition rate transverse excited atmospheric pressure CO2 laser operating at lambda=9.3 micro. J Biomed Opt. 2006 Nov-Dec; 11(6):064008. Fan K, Bell P, Fried D. PMID: 17212531.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    173. Adhesion of composite to enamel and dentin surfaces irradiated by IR laser pulses of 0.5-35 micros duration. J Biomed Mater Res B Appl Biomater. 2006 Oct; 79(1):193-201. Staninec M, Gardner AK, Le CQ, Sarma AV, Fried D. PMID: 16637032.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    174. Dissolution studies of bovine dental enamel surfaces modified by high-speed scanning ablation with a lambda = 9.3-microm TEA CO(2) laser. Lasers Surg Med. 2006 Oct; 38(9):837-45. Fried D, Featherstone JD, Le CQ, Fan K. PMID: 17044095.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    175. Remineralization of enamel caries can decrease optical reflectivity. J Dent Res. 2006 Sep; 85(9):804-8. Jones RS, Fried D. PMID: 16931861; PMCID: PMC2254215.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    176. Light scattering properties of natural and artificially demineralized dental enamel at 1310 nm. J Biomed Opt. 2006 May-Jun; 11(3):34023. Darling CL, Huynh GD, Fried D. PMID: 16822072.
      View in: PubMed   Mentions: 90     Fields:    Translation:Humans
    177. Remineralization of in vitro dental caries assessed with polarization-sensitive optical coherence tomography. J Biomed Opt. 2006 Jan-Feb; 11(1):014016. Jones RS, Darling CL, Featherstone JD, Fried D. PMID: 16526893.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    178. Imaging artificial caries on the occlusal surfaces with polarization-sensitive optical coherence tomography. Caries Res. 2006; 40(2):81-9. Jones RS, Darling CL, Featherstone JD, Fried D. PMID: 16508263.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    179. Early caries imaging and monitoring with near-infrared light. Dent Clin North Am. 2005 Oct; 49(4):771-93, vi. Fried D, Featherstone JD, Darling CL, Jones RS, Ngaotheppitak P, Bühler CM. PMID: 16150316.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    180. Measurement of the severity of natural smooth surface (interproximal) caries lesions with polarization sensitive optical coherence tomography. Lasers Surg Med. 2005 Jul; 37(1):78-88. Ngaotheppitak P, Darling CL, Fried D. PMID: 15889402.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    181. Imaging of occlusal dental caries (decay) with near-IR light at 1310-nm. Opt Express. 2005 Jan 24; 13(2):573-82. Bühler C, Ngaotheppitak P, Fried D. PMID: 19488387.
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    182. Selective removal of composite sealants with near-ultraviolet laser pulses of nanosecond duration. J Biomed Opt. 2005 Jan-Feb; 10(1):14001. Louie TM, Jones RS, Sarma AV, Fried D. PMID: 15847582.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    183. Transmission of Q-switched erbium:YSGG (lambda=2.79 microm) and erbium:YAG (lambda=2.94 microm) laser radiation through germanium oxide and sapphire optical fibres at high pulse energies. Lasers Med Sci. 2004; 19(3):155-60. Fried NM, Yang Y, Chaney CA, Fried D. PMID: 15645320.
      View in: PubMed   Mentions: 3     Fields:    
    184. Imaging artificial caries under composite sealants and restorations. J Biomed Opt. 2004 Nov-Dec; 9(6):1297-304. Jones RS, Staninec M, Fried D. PMID: 15568951.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    185. Peripheral thermal and mechanical damage to dentin with microsecond and sub-microsecond 9.6 microm, 2.79 microm, and 0.355 microm laser pulses. Lasers Surg Med. 2004; 35(3):214-28. Dela Rosa A, Sarma AV, Le CQ, Jones RS, Fried D. PMID: 15389737.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    186. Selective targeting of protein, water, and mineral in dentin using UV and IR pulse lasers: the effect on the bond strength to composite restorative materials. Lasers Surg Med. 2004; 35(4):245-53. Sheth KK, Staninec M, Sarma AV, Fried D. PMID: 15493023.
      View in: PubMed   Mentions: 14     Fields:    
    187. Pulpal safety of 9.6 microm TEA CO2 laser used for caries prevention. Lasers Surg Med. 2004; 35(2):104-10. Goodis HE, Fried D, Gansky S, Rechmann P, Featherstone JD. PMID: 15334612.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    188. Near-infrared transillumination at 1310-nm for the imaging of early dental decay. Opt Express. 2003 Sep 08; 11(18):2259-65. Jones R, Huynh G, Jones G, Fried D. PMID: 19466117.
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    189. Irradiation of dental enamel with Q-switched lambda = 355-nm laser pulses: surface morphology, fluoride adsorption, and adhesion to composite resin. Lasers Surg Med. 2003; 32(4):310-7. Wheeler CR, Fried D, Featherstone JD, Watanabe LG, Le CQ. PMID: 12696100.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    190. Influence of an optically thick water layer on the bond-strength of composite resin to dental enamel after IR laser ablation. Lasers Surg Med. 2003; 33(4):264-9. Staninec M, Xie J, Le CQ, Fried D. PMID: 14571452.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    191. Imaging caries lesions and lesion progression with polarization sensitive optical coherence tomography. J Biomed Opt. 2002 Oct; 7(4):618-27. Fried D, Xie J, Shafi S, Featherstone JD, Breunig TM, Le C. PMID: 12421130.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansAnimals
    192. Thermal and chemical modification of dentin by 9-11-microm CO2 laser pulses of 5-100-micros duration. Lasers Surg Med. 2002; 31(4):275-82. Fried D, Zuerlein MJ, Le CQ, Featherstone JD. PMID: 12355574.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    193. Selective ablation of surface enamel caries with a pulsed Nd:YAG dental laser. Lasers Surg Med. 2002; 30(5):342-50. Harris DM, White JM, Goodis H, Arcoria CJ, Simon J, Carpenter WM, Fried D, Burkart J, Yessik M, Myers T. PMID: 12116326.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    194. Selective removal of residual composite from dental enamel surfaces using the third harmonic of a Q-switched Nd:YAG laser. Lasers Surg Med. 2002; 30(3):240-5. Alexander R, Xie J, Fried D. PMID: 11891745.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    195. Mechanism of water augmentation during IR laser ablation of dental enamel. Lasers Surg Med. 2002; 31(3):186-93. Fried D, Ashouri N, Breunig T, Shori R. PMID: 12224092.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    196. Dental hard tissue modification and removal using sealed transverse excited atmospheric-pressure lasers operating at lambda=9.6 and 10.6 microm. J Biomed Opt. 2001 Apr; 6(2):231-8. Fried D, Ragadio J, Akrivou M, Featherstone JD, Murray MW, Dickenson KM. PMID: 11375734.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    197. Residual heat deposition in dental enamel during IR laser ablation at 2.79, 2.94, 9.6, and 10.6 microm. Lasers Surg Med. 2001; 29(3):221-9. Fried D, Ragadio J, Champion A. PMID: 11573223.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    198. Selective ablation of orthodontic composite by using sub-microsecond IR laser pulses with optical feedback. Lasers Surg Med. 2000; 27(2):103-10. Dumore T, Fried D. PMID: 10960816.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    199. Modeling the modification depth of carbon dioxide laser-treated dental enamel. Lasers Surg Med. 1999; 25(4):335-47. Zuerlein MJ, Fried D, Featherstone JD. PMID: 10534750.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    200. CO2 laser inhibitor of artificial caries-like lesion progression in dental enamel. J Dent Res. 1998 Jun; 77(6):1397-403. Featherstone JD, Barrett-Vespone NA, Fried D, Kantorowitz Z, Seka W. PMID: 9649168.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    201. Permanent and transient changes in the reflectance of CO2 laser-irradiated dental hard tissues at lambda = 9.3, 9.6, 10.3, and 10.6 microns and at fluences of 1-20 J/cm2. Lasers Surg Med. 1997; 20(1):22-31. Fried D, Glena RE, Featherstone JD, Seka W. PMID: 9041504.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
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