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Daniel Fried, PhD

Title(s)Professor, Preventive & Restor Dent Sci
SchoolSchool of Dentistry
Address707 Parnassus Ave
San Francisco CA 94143
Phone415-502-6641
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    Collapse Research 
    Collapse Research Activities and Funding
    Imaging Dental Caries with SWIR Light
    NIH R01DE028295Aug 1, 2019 - Apr 30, 2024
    Role: Principal Investigator
    Optical Methods for Lesion Activity Assessment
    NIH R01DE027335Sep 1, 2018 - Jun 30, 2023
    Role: Principal Investigator
    Selective Ablation of Dental Caries and Composites
    NIH R01DE019631Sep 1, 2009 - Aug 31, 2011
    Role: Principal Investigator
    Early Caries Detection with Near-IR Light
    NIH R01DE014698May 1, 2007 - May 31, 2006
    Role: Principal Investigator
    Clinical Assessment of Tooth Demineralization & Remineralization with PS-OCT
    NIH R01DE017869Aug 15, 2006 - Jul 31, 2016
    Role: Principal Investigator
    Laser Ablation of Dental Hard Tissues
    NIH R01DE014554Jun 1, 2002 - May 31, 2008
    Role: Principal Investigator
    MULTIPURPOSE CO2 TEA LASER FOR DENTAL APPLICATIONS
    NIH R41DE012971Aug 1, 2000 - Jul 31, 2001
    Role: Principal Investigator
    IR LASER ABLATION OF DENTAL HARD TISSUE
    NIH R29DE012091Aug 1, 1997 - May 31, 2003
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. High Contrast Reflectance Imaging of Enamel Demineralization and Remineralization at 1950-nm for the Assessment of Lesion Activity. Lasers Surg Med. 2021 Jan 13. Fried WA, Abdelaziz M, Darling CL, Fried D. PMID: 33442896.
      View in: PubMed   Mentions:    Fields:    
    2. Dual short wavelength infrared transillumination/reflectance mode imaging for caries detection. J Biomed Opt. 2021 Jan; 26(4). Zhu Y, Abdelaziz M, Simon J, Le O, Fried D. PMID: 33515220.
      View in: PubMed   Mentions:    Fields:    
    3. Thermal Imaging of Root Caries In Vivo. J Dent Res. 2020 Dec; 99(13):1502-1508. Yang V, Zhu Y, Curtis D, Le O, Chang NYN, Fried WA, Simon JC, Banan P, Darling CL, Fried D. PMID: 32866422.
      View in: PubMed   Mentions:    Fields:    
    4. A SWIR imaging handpiece for the clinical assessment of lesion activity via dehydration. Preclinical Assessment. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Fried WA, Zhu Y, Yang V, Chang NY, Fried D. PMID: 32194294.
      View in: PubMed   Mentions:
    5. In vivo spectral guided removal of composite from tooth surfaces with a CO2 laser. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Simon JC, Choi JH, Jang A, Fried D. PMID: 32161428.
      View in: PubMed   Mentions:
    6. A thermal imaging handpiece for the clinical assessment of lesion activity on root surfaces via dehydration. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Yang VB, Chang NY, Fried D. PMID: 32231402.
      View in: PubMed   Mentions:
    7. Enhancing the detection of proximal cavities on near infrared transillumination images with Indocyanine Green (ICG) as a contrast medium: In vitro proof of concept studies. J Dent. 2019 12; 91:103222. Abdelaziz M, Krejci I, Fried D. PMID: 31682898.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Measurement of the shrinkage of natural and simulated lesions on root surfaces using CP-OCT. J Dent. 2019 11; 90:103213. Yang V, Fried D. PMID: 31622647.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. In vitro longitudinal evaluation of enamel wear by cross-polarization optical coherence tomography. Dent Mater. 2019 10; 35(10):1464-1470. Alghilan MA, Lippert F, Platt JA, Eckert GJ, González-Cabezas C, Fried D, Hara AT. PMID: 31395451.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Image-Guided Ablation of Dental Calculus From Root Surfaces Using a DPSS Er:YAG Laser. Lasers Surg Med. 2020 03; 52(3):247-258. Fried WA, Chan KH, Darling CL, Curtis DA, Fried D. PMID: 31236996.
      View in: PubMed   Mentions: 1     Fields:    
    11. Near-infrared imaging of demineralization on the occlusal surfaces of teeth without the interference of stains. J Biomed Opt. 2019 03; 24(3):1-8. Ng C, Almaz E, Simon J, Fried D, Darling C. PMID: 30834721.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. The Relationship of Dehydration Rate and Transparent Surface Layer Thickness for Coronal Lesions on Extracted Teeth. Proc SPIE Int Soc Opt Eng. 2019 Feb; 10857. Chang NN, Abdelaziz M, Fried D. PMID: 30918416.
      View in: PubMed   Mentions:
    13. An appliance for monitoring the shrinkage of root caries with OCT. Proc SPIE Int Soc Opt Eng. 2019 Feb; 10857. Yang VB, Fried D. PMID: 30918417.
      View in: PubMed   Mentions:
    14. Selective removal of dental calculus with a diode-pumped Er:YAG laser. Proc SPIE Int Soc Opt Eng. 2019 Feb; 10857. Fried WA, Chan KH, Darling CL, Fried D. PMID: 31000908.
      View in: PubMed   Mentions:
    15. The contrast of demineralization on tooth occlusal surfaces from 405 to 1950-nm with varying depth. Proc SPIE Int Soc Opt Eng. 2019 Feb; 10857. Mohajerani N, Chan KH, Yang VB, Fried D, Darling CL. PMID: 30923417.
      View in: PubMed   Mentions:
    16. Image guided laser ablation of demineralization from root surfaces. Proc SPIE Int Soc Opt Eng. 2019 Feb; 10857. Dhillon N, Chan KH, Yang VB, Fried D. PMID: 31007338.
      View in: PubMed   Mentions:
    17. Impact of surface micromorphology and demineralization severity on enamel loss measurements by cross-polarization optical coherence tomography. J Dent. 2019 02; 81:52-58. Alghilan MA, Lippert F, Platt JA, Eckert GJ, González-Cabezas C, Fried D, Hara AT. PMID: 30582963.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Use of a DPSS Er:YAG laser for the selective removal of composite from tooth surfaces. Biomed Opt Express. 2018 Oct 01; 9(10):5026-5036. Fried WA, Chan KH, Darling CL, Fried D. PMID: 30319919.
      View in: PubMed   Mentions:
    19. Selective ablation of dental caries using coaxial Co2 (9.3-µm) and near-IR (1880-nm) lasers. Lasers Surg Med. 2019 02; 51(2):176-184. Chan KH, Fried D. PMID: 30024032.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    20. Cross-polarization reflectance imaging of root caries and dental calculus on extracted teeth at wavelengths from 400 to 2350 nm. J Biophotonics. 2018 11; 11(11):e201800113. Yang VB, Curtis DA, Fried D. PMID: 29952066.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. Optical Coherence Tomography. Dent Clin North Am. 2018 Jul; 62(3):421-434. Katkar RA, Tadinada SA, Amaechi BT, Fried D. PMID: 29903559.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    22. Fluorescence and Near-Infrared Light Transillumination. Dent Clin North Am. 2018 Jul; 62(3):435-452. Amaechi BT, Owosho AA, Fried D. PMID: 29903560.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Multispectral cross-polarization reflectance measurements suggest high contrast of demineralization on tooth surfaces at wavelengths beyond 1300 nm due to reduced light scattering in sound enamel. J Biomed Opt. 2018 06; 23(6):1-4. Chan KH, Fried D. PMID: 29877068.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. Multispectral near-infrared reflectance and transillumination imaging of occlusal carious lesions: Variation in lesion contrast with lesion depth. Proc SPIE Int Soc Opt Eng. 2018 Jan-Feb; 10473. Simon JC, Curtis DA, Darling CL, Fried D. PMID: 29497229.
      View in: PubMed   Mentions:
    25. Image-guided Removal of Interproximal Lesions with a CO2 Laser. Proc SPIE Int Soc Opt Eng. 2018 Jan-Feb; 10473. Ngo A, Chan KH, Le O, Simon JC, Fried D. PMID: 29497230.
      View in: PubMed   Mentions:
    26. SWIR reflectance imaging of demineralization on the occlusal surfaces of teeth beyond 1700 nm. Proc SPIE Int Soc Opt Eng. 2018 Jan-Feb; 10473. Ng C, Simon JC, Fried D, Darling CL. PMID: 30686852.
      View in: PubMed   Mentions:
    27. Lesion Dehydration Rate Changes with the Surface Layer Thickness during Enamel Remineralization. Proc SPIE Int Soc Opt Eng. 2018 Feb; 10473. Chang NN, Jew JM, Fried D. PMID: 30034077.
      View in: PubMed   Mentions:
    28. Selective Ablation of Carious Lesions using an Integrated Near-IR Imaging System and a Novel 9.3-µm CO2 Laser. Proc SPIE Int Soc Opt Eng. 2018 Feb; 10473. Chan KH, Fried NM, Fried D. PMID: 30034078.
      View in: PubMed   Mentions:
    29. Influence of multi-wavelength laser irradiation of enamel and dentin surfaces at 0.355, 2.94, and 9.4?µm on surface morphology, permeability, and acid resistance. Lasers Surg Med. 2017 12; 49(10):913-927. Chang NN, Jew JM, Simon JC, Chen KH, Lee RC, Fried WA, Cho J, Darling CL, Fried D. PMID: 28699676.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    30. Automated ablation of dental composite using an IR pulsed laser coupled to a plume emission spectral feedback system. Lasers Surg Med. 2017 09; 49(7):658-665. PMID: 28467687.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    31. Near-IR and CP-OCT imaging of suspected occlusal caries lesions. Lasers Surg Med. 2017 03; 49(3):215-224. PMID: 28339115.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    32. Influence of a pulsed CO2 laser operating at 9.4??µm on the surface morphology, reflectivity, and acid resistance of dental enamel below the threshold for melting. J Biomed Opt. 2017 02 01; 22(2):28001. Kim JW, Lee R, Chan KH, Jew JM, Fried D. PMID: 28145558.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    33. Optical changes of dentin in the near-IR as a function of mineral content. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. PMID: 28450756.
      View in: PubMed   Mentions:
    34. Automated ablation of dental composite using an IR pulsed laser coupled to a plume emission spectral feedback system. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Jang AT, Chan KH, Fried D. PMID: 28479654.
      View in: PubMed   Mentions:
    35. High-Contrast Reflectance Imaging of Composite Restorations Color-Matched to Tooth Structure at 1000-2300-nm. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. PMID: 28626287.
      View in: PubMed   Mentions:
    36. Influence of Multi-Wavelength Laser Irradiation of Enamel and Dentin Surfaces on Surface Morphology and Permeability. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. PMID: 28680191.
      View in: PubMed   Mentions:
    37. Assessment of cavitation in artificial approximal dental lesions with near-IR imaging. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. PMID: 28626283.
      View in: PubMed   Mentions:
    38. Near-infrared imaging of enamel hypomineralization due to developmental defects. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. PMID: 28626284.
      View in: PubMed   Mentions:
    39. Selective Laser Ablation of Carious Lesions using Simultaneous Scanned Near-IR Diode and CO2 Lasers. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. PMID: 28626285.
      View in: PubMed   Mentions:
    40. Synergistic effect of fluoride and laser irradiation for the inhibition of the demineralization of dental enamel. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. PMID: 28626286.
      View in: PubMed   Mentions:
    41. Assessment of radicular dentin permeability after irradiation with CO2 laser and endodontic irrigation treatments with thermal imaging. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. PMID: 28626288.
      View in: PubMed   Mentions:
    42. Selective removal of natural caries lesions from dentin and tooth occlusal surfaces using a diode-pumped Er:YAG laser. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. PMID: 28450757.
      View in: PubMed   Mentions:
    43. Use of an optical clearing agent to enhance the visibility of subsurface structures and lesions from tooth occlusal surfaces. J Biomed Opt. 2016 Aug; 21(8):081206. PMID: 27071709.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    44. Enamel Thickness Determination by Optical Coherence Tomography: In vitro Validation. Caries Res. 2016; 50(4):400-6. PMID: 27454764.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    45. Near-IR transillumination and reflectance imaging at 1,300?nm and 1,500-1,700?nm for in vivo caries detection. Lasers Surg Med. 2016 11; 48(9):828-836. Simon JC, Lucas SA, Staninec M, Tom H, Chan KH, Darling CL, Cozin MJ, Lee RC, Fried D. PMID: 27389018.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    46. Activity assessment of root caries lesions with thermal and near-IR imaging methods. J Biophotonics. 2017 Mar; 10(3):433-445. PMID: 27060450.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    47. Infrared Methods for Assessment of the Activity of Natural Enamel Caries Lesions. IEEE J Sel Top Quantum Electron. 2016 May-Jun; 22(3). PMID: 27642246.
      View in: PubMed   Mentions:
    48. Clinical monitoring of smooth surface enamel lesions using CP-OCT during nonsurgical intervention. Lasers Surg Med. 2016 12; 48(10):915-923. PMID: 26955902.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    49. Selective removal of esthetic composite restorations with spectral guided laser ablation. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 26997742.
      View in: PubMed   Mentions:
    50. A system for simultaneous near-infrared reflectance and transillumination imaging of occlusal carious lesions. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 27006524.
      View in: PubMed   Mentions:
    51. Influence of stains on lesion contrast in the pits and fissures of tooth occlusal surfaces from 800-1600-nm. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 26997740.
      View in: PubMed   Mentions:
    52. Assessment of simulated lesions on primary teeth with near-infrared imaging. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 26997743.
      View in: PubMed   Mentions:
    53. A new sealed RF-excited CO2 laser for enamel ablation operating at 9.4-µm with a pulse duration of 26-µs. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 27006521.
      View in: PubMed   Mentions:
    54. Assessment of remineralized dentin lesions with thermal and near-infrared reflectance imaging. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 27006522.
      View in: PubMed   Mentions:
    55. Evaluation of enamel surface modification using PS-OCT after laser treatment to increase resistance to demineralization. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 27006523.
      View in: PubMed   Mentions:
    56. Enhancement of OCT images with vinyl polysiloxane (VPS). Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 27011417.
      View in: PubMed   Mentions:
    57. Selective removal of dental composite with a diode-pumped Er:YAG laser. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. PMID: 26997741.
      View in: PubMed   Mentions:
    58. Near-infrared imaging of secondary caries lesions around composite restorations at wavelengths from 1300-1700-nm. Dent Mater. 2016 Apr; 32(4):587-95. PMID: 26876234.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    59. Near-IR image-guided laser ablation of demineralization on tooth occlusal surfaces. Lasers Surg Med. 2016 Jan; 48(1):52-61. PMID: 26763111.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    60. Assessment of remineralization via measurement of dehydration rates with thermal and near-IR reflectance imaging. J Dent. 2015 Aug; 43(8):1032-42. PMID: 25862275.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    61. Enhanced detection of dentinal lesions in OCT images using the RKT transformation. Proc SPIE Int Soc Opt Eng. 2015 Feb 24; 9306. PMID: 25914493.
      View in: PubMed   Mentions:
    62. In vitro near-infrared imaging of natural secondary caries. Proc SPIE Int Soc Opt Eng. 2015 Feb 24; 9306. PMID: 25914495.
      View in: PubMed   Mentions:
    63. Selective removal of dental caries with a diode-pumped Er:YAG laser. Proc SPIE Int Soc Opt Eng. 2015 Feb 24; 9306. PMID: 25914496.
      View in: PubMed   Mentions:
    64. Selective removal of demineralized enamel using a CO2 laser coupled with near-IR reflectance imaging. Proc SPIE Int Soc Opt Eng. 2015 Feb 24; 9306. PMID: 25914497.
      View in: PubMed   Mentions:
    65. Image-guided removal of occlusal caries lesions with a ?= 9.3-µm CO2 laser using near-IR transillumination. Proc SPIE Int Soc Opt Eng. 2015 Feb 24; 9306. Chung LC, Tom H, Chan KH, Simon JC, Fried D, Darling CL. PMID: 25914498.
      View in: PubMed   Mentions:
    66. Serial removal of caries lesions from tooth occlusal surfaces using near-IR image-guided IR laser ablation. Proc SPIE Int Soc Opt Eng. 2015 Feb 24; 9306. PMID: 25914499.
      View in: PubMed   Mentions:
    67. Assessment of remineralization in simulated enamel lesions via dehydration with near-IR reflectance imaging. Proc SPIE Int Soc Opt Eng. 2015 Feb 24; 9306. PMID: 25914494.
      View in: PubMed   Mentions:
    68. A method for monitoring enamel erosion using laser irradiated surfaces and optical coherence tomography. Lasers Surg Med. 2014 Nov; 46(9):672-8. PMID: 25147133.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    69. Automated assessment of the remineralization of artificial enamel lesions with polarization-sensitive optical coherence tomography. Biomed Opt Express. 2014 Sep 01; 5(9):2950-62. PMID: 25401009.
      View in: PubMed   Mentions:
    70. Longitudinal monitoring of demineralization peripheral to orthodontic brackets using cross polarization optical coherence tomography. J Dent. 2014 May; 42(5):547-55. PMID: 24561340.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    71. High contrast optical imaging methods for image guided laser ablation of dental caries lesions. Proc SPIE Int Soc Opt Eng. 2014 Feb 18; 8929. PMID: 24791129.
      View in: PubMed   Mentions:
    72. Transillumination and reflectance probes for in vivo near-IR imaging of dental caries. Proc SPIE Int Soc Opt Eng. 2014 Feb 18; 8929:89290D. PMID: 24817803.
      View in: PubMed   Mentions:
    73. Automated detection of remineralization in simulated enamel lesions with PS-OCT. Proc SPIE Int Soc Opt Eng. 2014 Feb 18; 8929:89290E. PMID: 25075267.
      View in: PubMed   Mentions:
    74. Monitoring the inhibition of erosion by a CO2 laser with OCT. Proc SPIE Int Soc Opt Eng. 2014 Feb 18; 8929:89290F. PMID: 24817804.
      View in: PubMed   Mentions:
    75. Enhancing the detection of hidden occlusal caries lesions with OCT using high index liquids. Proc SPIE Int Soc Opt Eng. 2014 Feb 18; 8929:89290O. PMID: 24817805.
      View in: PubMed   Mentions:
    76. Near-IR imaging of cracks in teeth. Proc SPIE Int Soc Opt Eng. 2014 Feb 18; 8929:89290Q. PMID: 24817806.
      View in: PubMed   Mentions:
    77. Near-IR imaging of demineralization under sealants. Proc SPIE Int Soc Opt Eng. 2014 Feb 18; 8929:89290S. PMID: 24817807.
      View in: PubMed   Mentions:
    78. Attenuation of near-IR light through dentin at wavelengths from 1300-1650-nm. Proc SPIE Int Soc Opt Eng. 2014 Feb 18; 8929:89290M. PMID: 24839373.
      View in: PubMed   Mentions:
    79. Analysis of enamel surface damage after selective laser ablation of composite from tooth surfaces. Photonics Lasers Med. 2014 Feb 01; 3(1):37-45. PMID: 24707453.
      View in: PubMed   Mentions:
    80. Near-infrared imaging of demineralization under sealants. J Biomed Opt. 2014; 19(7):77003. PMID: 25036214.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    81. Multispectral near-IR reflectance imaging of simulated early occlusal lesions: variation of lesion contrast with lesion depth and severity. Lasers Surg Med. 2014 Mar; 46(3):203-15. PMID: 24375543.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    82. Use of 2D images of depth and integrated reflectivity to represent the severity of demineralization in cross-polarization optical coherence tomography. J Biophotonics. 2015 Jan; 8(1-2):36-45. PMID: 24307350.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    83. High contrast reflectance imaging of simulated lesions on tooth occlusal surfaces at near-IR wavelengths. Lasers Surg Med. 2013 Oct; 45(8):533-41. PMID: 23857066.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    84. Methods for Monitoring Erosion Using Optical Coherence Tomography. Proc SPIE Int Soc Opt Eng. 2013 Mar 25; 8566:856606. PMID: 24465117.
      View in: PubMed   Mentions:
    85. Clinical Monitoring of Early Caries Lesions using Cross Polarization Optical Coherence Tomography. Proc SPIE Int Soc Opt Eng. 2013 Mar 25; 8566. PMID: 24353384.
      View in: PubMed   Mentions:
    86. Imaging Early Demineralization on Tooth Occlusal Surfaces with a High Definition InGaAs Camera. Proc SPIE Int Soc Opt Eng. 2013 Mar 25; 8566. PMID: 24357911.
      View in: PubMed   Mentions:
    87. Monitoring the Remineralization of Early Simulated Lesions using a pH Cycling Model with CP-OCT. Proc SPIE Int Soc Opt Eng. 2013 Mar 25; 8566. PMID: 24353383.
      View in: PubMed   Mentions:
    88. Remineralization of Root Caries Monitored Using Cross-Polarization Optical Coherence Tomography. Proc SPIE Int Soc Opt Eng. 2012 Feb 09; 8208. PMID: 24357904.
      View in: PubMed   Mentions:
    89. Nondestructive Monitoring of the Repair of Natural Occlusal Lesions using Cross - Polarization Optical Coherence Tomography. Proc SPIE Int Soc Opt Eng. 2012 Feb 09; 8208. PMID: 23538837.
      View in: PubMed   Mentions:
    90. Investigation of Acid-Etched CO2 Laser Ablated Enamel Surfaces Using Polarization Sensitive Optical Coherence Tomography. Proc SPIE Int Soc Opt Eng. 2012 Feb 09; 8208. PMID: 23539418.
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    91. Monitoring tooth demineralization using a cross polarization optical coherence tomographic system with an integrated MEMS scanner. Proc SPIE Int Soc Opt Eng. 2012 Feb 09; 8208. PMID: 24357905.
      View in: PubMed   Mentions:
    92. Selective Removal of Demineralization Using Near Infrared Cross Polarization Reflectance and a Carbon Dioxide Laser. Proc SPIE Int Soc Opt Eng. 2012 Feb 09; 8208. PMID: 24357906.
      View in: PubMed   Mentions:
    93. Nondestructive monitoring of the repair of enamel artificial lesions by an acidic remineralization model using polarization-sensitive optical coherence tomography. Dent Mater. 2012 May; 28(5):488-94. PMID: 22204914.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    94. Non-destructive clinical assessment of occlusal caries lesions using near-IR imaging methods. Lasers Surg Med. 2011 Dec; 43(10):951-9. PMID: 22109697.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    95. Multispectral near-IR reflectance and transillumination imaging of teeth. Biomed Opt Express. 2011 Oct 01; 2(10):2804-14. PMID: 22025986.
      View in: PubMed   Mentions:
    96. Rapid and selective removal of composite from tooth surfaces with a 9.3 µm CO2 laser using spectral feedback. Lasers Surg Med. 2011 Sep; 43(8):824-32. PMID: 21956630.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    97. Caries inhibition in vital teeth using 9.6-µm CO2-laser irradiation. J Biomed Opt. 2011 Jul; 16(7):071405. PMID: 21806251.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    98. High-speed scanning ablation of dental hard tissues with a ? = 9.3 µm CO2 laser: adhesion, mechanical strength, heat accumulation, and peripheral thermal damage. J Biomed Opt. 2011 Jul; 16(7):071410. PMID: 21806256.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    99. In vivo Near-IR Imaging of Occlusal Lesions at 1310-nm. Proc SPIE Int Soc Opt Eng. 2011 Jan 23; 7884(78840B). Fried D, Staninec M, Darling CL, Lee C, Kang H, Chan KH. PMID: 21785532.
      View in: PubMed   Mentions:
    100. Repair of Artificial Lesions using an Acidic Remineralization Model Monitored with Cross - Polarization Optical Coherence Tomography. Proc SPIE Int Soc Opt Eng. 2011 Jan 23; 7884(78840Q). PMID: 21785533.
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    101. Adhesion studies on dental enamel surfaces irradiated by a rapidly scanned carbon dioxide laser. Proc SPIE Int Soc Opt Eng. 2011 Jan 01; 7884. PMID: 21998494.
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    102. Near infrared imaging of teeth at wavelengths between 1200 and 1600 nm. Proc SPIE Int Soc Opt Eng. 2011 Jan 01; 7884. PMID: 22399836.
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    103. Polarization Resolved Near-IR Imaging of Sound and Carious Dental Enamel. Proc SPIE Int Soc Opt Eng. 2011 Jan 01; 7884. PMID: 22399837.
      View in: PubMed   Mentions:
    104. Selective Removal of Dental Composite using a Rapidly Scanned Carbon Dioxide Laser. Proc SPIE Int Soc Opt Eng. 2011; 7884:78840R1-78840R5. Chan KH, Fried D. PMID: 21927546.
      View in: PubMed   Mentions:
    105. Clinical assessment of early tooth demineralization using polarization sensitive optical coherence tomography. Lasers Surg Med. 2010 Dec; 42(10):738-45. Louie T, Lee C, Hsu D, Hirasuna K, Manesh S, Staninec M, Darling CL, Fried D. PMID: 21246578.
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    106. Nondestructive assessment of the severity of occlusal caries lesions with near-infrared imaging at 1310 nm. J Biomed Opt. 2010 Jul-Aug; 15(4):047011. Lee C, Lee D, Darling CL, Fried D. PMID: 20799842.
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    107. Nondestructive Assessment of Early Tooth Demineralization Using Cross-Polarization Optical Coherence Tomography. IEEE J Sel Top Quantum Electron. 2010 Jul; 16(4):870-876. Kang H, Jiao JJ, Lee C, Le MH, Darling CL, Fried D. PMID: 21660217.
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    108. In vivo near-IR imaging of approximal dental decay at 1,310 nm. Lasers Surg Med. 2010 Apr; 42(4):292-8. Staninec M, Lee C, Darling CL, Fried D. PMID: 20432277.
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    109. Imaging Simulated Secondary Caries Lesions with Cross Polarization OCT. Proc SPIE Int Soc Opt Eng. 2010 Mar 05; 7549:754905. Stahl J, Kang H, Fried D. PMID: 21892257.
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    110. Near-IR Imaging of Thermal Changes in Enamel during Laser Ablation. Proc SPIE Int Soc Opt Eng. 2010 Mar 05; 7546(1). Maung LH, Lee C, Fried D. PMID: 21935291.
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    111. In vitro near-infrared imaging of occlusal dental caries using germanium enhanced CMOS camera. Proc SPIE Int Soc Opt Eng. 2010 Mar 01; 7549. PMID: 22162916.
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    112. Near-IR Polarization Imaging of Sound and Carious Dental Enamel. Proc SPIE Int Soc Opt Eng. 2010; 7549:75490L. PMID: 22228980.
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    113. Automated analysis of lesion depth and integrated reflectivity in PS-OCT scans of tooth demineralization. Lasers Surg Med. 2010 Jan; 42(1):62-8. Le MH, Darling CL, Fried D. PMID: 20077486.
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    114. Imaging early demineralization with PS-OCT. Proc SPIE Int Soc Opt Eng. 2010 Jan 01; 7549. PMID: 22399835.
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    115. Imaging Natural Occlusal Caries Lesions with Optical Coherence Tomography. Proc SPIE Int Soc Opt Eng. 2010; 7549:75490N. PMID: 22228981.
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    116. Near-infrared image-guided laser ablation of dental decay. J Biomed Opt. 2009 Sep-Oct; 14(5):054045. Tao YC, Fried D. PMID: 19895146.
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    117. Nondestructive assessment of dentin demineralization using polarization-sensitive optical coherence tomography after exposure to fluoride and laser irradiation. . 2009 Aug; 90(2):802-12. Manesh SK, Darling CL, Fried D. PMID: 19283826.
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    118. Polarization-sensitive optical coherence tomography for the nondestructive assessment of the remineralization of dentin. J Biomed Opt. 2009 Jul-Aug; 14(4):044002. Manesh SK, Darling CL, Fried D. PMID: 19725714.
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    119. Pulpal effects of enamel ablation with a microsecond pulsed lambda = 9.3-microm CO2 laser. Lasers Surg Med. 2009 Apr; 41(4):256-63. Staninec M, Darling CL, Goodis HE, Pierre D, Cox DP, Fan K, Larson M, Parisi R, Hsu D, Manesh SK, Ho C, Hosseini M, Fried D. PMID: 19347946.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    120. Non-destructive measurement of demineralization & remineralization in the occlusal pits and fissures of extracted 3 molars with PS-OCT. Proc SPIE Int Soc Opt Eng. 2009 Mar 06; 7162(1). PMID: 21935289.
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    121. High contrast near-infrared polarized reflectance images of demineralization on tooth buccal and occlusal surfaces at lambda = 1310-nm. Lasers Surg Med. 2009 Mar; 41(3):208-13. Wu J, Fried D. PMID: 19291753.
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    122. Dentin bond strength after ablation using a CO(2) laser operating at high pulse repetition rates. Proc SPIE Int Soc Opt Eng. 2009 Feb 18; 7162:71620F. Hedayatollahnajafi S, Staninec M, Watanabe L, Lee C, Fried D. PMID: 21892256.
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    123. An Automated Digital Microradiography System for Assessing Tooth Demineralization. Proc SPIE Int Soc Opt Eng. 2009 Feb 18; 7162(1). PMID: 21935288.
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    124. Methods for calculating the severity of demineralization on tooth surfaces from PS-OCT scans. Proc SPIE Int Soc Opt Eng. 2009 Feb 18; 7162(1). PMID: 21935290.
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    125. Polarization-sensitive optical coherence tomographic imaging of artificial demineralization on exposed surfaces of tooth roots. Dent Mater. 2009 Jun; 25(6):721-8. Lee C, Darling CL, Fried D. PMID: 19167052.
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    126. Dentin caries zones: mineral, structure, and properties. J Dent Res. 2009 Jan; 88(1):71-6. Pugach MK, Strother J, Darling CL, Fried D, Gansky SA, Marshall SJ, Marshall GW. PMID: 19131321.
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    127. Assessment of Dentin Remineralization with PS-OCT. Proc SPIE Int Soc Opt Eng. 2009 Jan 01; 7162. PMID: 21998493.
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    128. Near-IR Multi-modal Imaging of Natural Occlusal Lesions. Proc SPIE Int Soc Opt Eng. 2009; 7162:71620X. PMID: 22228979.
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    129. Weakening of dentin from cracks resulting from laser irradiation. Dent Mater. 2009 Apr; 25(4):520-5. Staninec M, Meshkin N, Manesh SK, Ritchie RO, Fried D. PMID: 19062088.
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    130. Nondestructive assessment of the inhibition of enamel demineralization by CO2 laser treatment using polarization sensitive optical coherence tomography. J Biomed Opt. 2008 Sep-Oct; 13(5):054027. Hsu DJ, Darling CL, Lachica MM, Fried D. PMID: 19021407.
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    131. Non-destructive assessment of inhibition of demineralization in dental enamel irradiated by a lambda=9.3-microm CO2 laser at ablative irradiation intensities with PS-OCT. Lasers Surg Med. 2008 Jul; 40(5):342-9. Can AM, Darling CL, Ho C, Fried D. PMID: 18563781.
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    132. Near-infrared imaging of developmental defects in dental enamel. J Biomed Opt. 2008 Jul-Aug; 13(4):044011. Hirasuna K, Fried D, Darling CL. PMID: 19021339.
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    133. Imaging laser irradiated enamel surfaces with polarization sensitive optical coherence tomography. Proc SPIE Int Soc Opt Eng. 2008 Mar; 6843:8430N-N8430. PMID: 21909224.
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    134. Selective Removal of Natural Occlusal Caries by Coupling Near-infrared Imaging with a CO(2) Laser. Proc SPIE Int Soc Opt Eng. 2008 Mar; 6843:68430I-68430I8. PMID: 21909225.
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    135. High-resolution PS-OCT of Enamel Remineralization. Proc SPIE Int Soc Opt Eng. 2008 Mar; 6843:68430T1-68430T7. Can AM, Darling CL, Fried D. PMID: 21909226.
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    136. Real-time near IR (1310 nm) imaging of CO2 laser ablation of enamel. Opt Express. 2008 Feb 18; 16(4):2685-93. Darling CL, Fried D. PMID: 18542353.
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    137. Near-IR imaging of Erbium Laser Ablation with a Water Spray. Proc SPIE Int Soc Opt Eng. 2008 Jan 20; 6843(684303). PMID: 21892255.
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    138. Imaging natural and artificial demineralization on dentin surfaces with polarization sensitive optical coherence tomography. Proc SPIE Int Soc Opt Eng. 2008 Jan 01; 6843. PMID: 21998492.
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    139. Ablation of Dental Hard Tissues with a Microsecond Pulsed Carbon Dioxide Laser Operating at 9.3-µm with an Integrated Scanner. Proc SPIE Int Soc Opt Eng. 2008; 6843:684308. PMID: 22228978.
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    140. Nondestructive measurement of the inhibition of demineralization on smooth surfaces using polarization-sensitive optical coherence tomography. Lasers Surg Med. 2007 Jun; 39(5):422-7. Chong SL, Darling CL, Fried D. PMID: 17565731.
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    141. Near-infrared image-guided laser ablation of artificial caries lesions. Proc SPIE Int Soc Opt Eng. 2007; 6425:64250T. PMID: 22866210.
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    142. Rapid and conservative ablation and modification of enamel, dentin, and alveolar bone using a high repetition rate transverse excited atmospheric pressure CO2 laser operating at lambda=9.3 micro. J Biomed Opt. 2006 Nov-Dec; 11(6):064008. Fan K, Bell P, Fried D. PMID: 17212531.
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    143. Adhesion of composite to enamel and dentin surfaces irradiated by IR laser pulses of 0.5-35 micros duration. . 2006 Oct; 79(1):193-201. Staninec M, Gardner AK, Le CQ, Sarma AV, Fried D. PMID: 16637032.
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    144. Dissolution studies of bovine dental enamel surfaces modified by high-speed scanning ablation with a lambda = 9.3-microm TEA CO(2) laser. Lasers Surg Med. 2006 Oct; 38(9):837-45. Fried D, Featherstone JD, Le CQ, Fan K. PMID: 17044095.
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    145. Remineralization of enamel caries can decrease optical reflectivity. J Dent Res. 2006 Sep; 85(9):804-8. Jones RS, Fried D. PMID: 16931861.
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    146. Light scattering properties of natural and artificially demineralized dental enamel at 1310 nm. J Biomed Opt. 2006 May-Jun; 11(3):34023. Darling CL, Huynh GD, Fried D. PMID: 16822072.
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    147. Imaging artificial caries on the occlusal surfaces with polarization-sensitive optical coherence tomography. Caries Res. 2006; 40(2):81-9. Jones RS, Darling CL, Featherstone JD, Fried D. PMID: 16508263.
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    148. Remineralization of in vitro dental caries assessed with polarization-sensitive optical coherence tomography. J Biomed Opt. 2006 Jan-Feb; 11(1):014016. Jones RS, Darling CL, Featherstone JD, Fried D. PMID: 16526893.
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    149. Early caries imaging and monitoring with near-infrared light. Dent Clin North Am. 2005 Oct; 49(4):771-93, vi. Fried D, Featherstone JD, Darling CL, Jones RS, Ngaotheppitak P, Bühler CM. PMID: 16150316.
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    150. Measurement of the severity of natural smooth surface (interproximal) caries lesions with polarization sensitive optical coherence tomography. Lasers Surg Med. 2005 Jul; 37(1):78-88. Ngaotheppitak P, Darling CL, Fried D. PMID: 15889402.
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    151. Imaging of occlusal dental caries (decay) with near-IR light at 1310-nm. Opt Express. 2005 Jan 24; 13(2):573-82. Bühler C, Ngaotheppitak P, Fried D. PMID: 19488387.
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    152. Selective removal of composite sealants with near-ultraviolet laser pulses of nanosecond duration. J Biomed Opt. 2005 Jan-Feb; 10(1):14001. Louie TM, Jones RS, Sarma AV, Fried D. PMID: 15847582.
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    153. Transmission of Q-switched erbium:YSGG (lambda=2.79 microm) and erbium:YAG (lambda=2.94 microm) laser radiation through germanium oxide and sapphire optical fibres at high pulse energies. Lasers Med Sci. 2004; 19(3):155-60. Fried NM, Yang Y, Chaney CA, Fried D. PMID: 15645320.
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    154. Imaging artificial caries under composite sealants and restorations. J Biomed Opt. 2004 Nov-Dec; 9(6):1297-304. Jones RS, Staninec M, Fried D. PMID: 15568951.
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    155. Pulpal safety of 9.6 microm TEA CO2 laser used for caries prevention. Lasers Surg Med. 2004; 35(2):104-10. Goodis HE, Fried D, Gansky S, Rechmann P, Featherstone JD. PMID: 15334612.
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    156. Peripheral thermal and mechanical damage to dentin with microsecond and sub-microsecond 9.6 microm, 2.79 microm, and 0.355 microm laser pulses. Lasers Surg Med. 2004; 35(3):214-28. Dela Rosa A, Sarma AV, Le CQ, Jones RS, Fried D. PMID: 15389737.
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    157. Selective targeting of protein, water, and mineral in dentin using UV and IR pulse lasers: the effect on the bond strength to composite restorative materials. Lasers Surg Med. 2004; 35(4):245-53. Sheth KK, Staninec M, Sarma AV, Fried D. PMID: 15493023.
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    158. Near-infrared transillumination at 1310-nm for the imaging of early dental decay. Opt Express. 2003 Sep 08; 11(18):2259-65. Jones R, Huynh G, Jones G, Fried D. PMID: 19466117.
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    159. Irradiation of dental enamel with Q-switched lambda = 355-nm laser pulses: surface morphology, fluoride adsorption, and adhesion to composite resin. Lasers Surg Med. 2003; 32(4):310-7. Wheeler CR, Fried D, Featherstone JD, Watanabe LG, Le CQ. PMID: 12696100.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    160. Influence of an optically thick water layer on the bond-strength of composite resin to dental enamel after IR laser ablation. Lasers Surg Med. 2003; 33(4):264-9. Staninec M, Xie J, Le CQ, Fried D. PMID: 14571452.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    161. Imaging caries lesions and lesion progression with polarization sensitive optical coherence tomography. J Biomed Opt. 2002 Oct; 7(4):618-27. Fried D, Xie J, Shafi S, Featherstone JD, Breunig TM, Le C. PMID: 12421130.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansAnimals
    162. Thermal and chemical modification of dentin by 9-11-microm CO2 laser pulses of 5-100-micros duration. Lasers Surg Med. 2002; 31(4):275-82. Fried D, Zuerlein MJ, Le CQ, Featherstone JD. PMID: 12355574.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    163. Selective ablation of surface enamel caries with a pulsed Nd:YAG dental laser. Lasers Surg Med. 2002; 30(5):342-50. Harris DM, White JM, Goodis H, Arcoria CJ, Simon J, Carpenter WM, Fried D, Burkart J, Yessik M, Myers T. PMID: 12116326.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    164. Selective removal of residual composite from dental enamel surfaces using the third harmonic of a Q-switched Nd:YAG laser. Lasers Surg Med. 2002; 30(3):240-5. Alexander R, Xie J, Fried D. PMID: 11891745.
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    165. Mechanism of water augmentation during IR laser ablation of dental enamel. Lasers Surg Med. 2002; 31(3):186-93. Fried D, Ashouri N, Breunig T, Shori R. PMID: 12224092.
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    166. Dental hard tissue modification and removal using sealed transverse excited atmospheric-pressure lasers operating at lambda=9.6 and 10.6 microm. J Biomed Opt. 2001 Apr; 6(2):231-8. Fried D, Ragadio J, Akrivou M, Featherstone JD, Murray MW, Dickenson KM. PMID: 11375734.
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    167. Residual heat deposition in dental enamel during IR laser ablation at 2.79, 2.94, 9.6, and 10.6 microm. Lasers Surg Med. 2001; 29(3):221-9. Fried D, Ragadio J, Champion A. PMID: 11573223.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    168. Selective ablation of orthodontic composite by using sub-microsecond IR laser pulses with optical feedback. Lasers Surg Med. 2000; 27(2):103-10. Dumore T, Fried D. PMID: 10960816.
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    169. Modeling the modification depth of carbon dioxide laser-treated dental enamel. Lasers Surg Med. 1999; 25(4):335-47. Zuerlein MJ, Fried D, Featherstone JD. PMID: 10534750.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    170. CO2 laser inhibitor of artificial caries-like lesion progression in dental enamel. J Dent Res. 1998 Jun; 77(6):1397-403. Featherstone JD, Barrett-Vespone NA, Fried D, Kantorowitz Z, Seka W. PMID: 9649168.
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    171. Permanent and transient changes in the reflectance of CO2 laser-irradiated dental hard tissues at lambda = 9.3, 9.6, 10.3, and 10.6 microns and at fluences of 1-20 J/cm2. Lasers Surg Med. 1997; 20(1):22-31. Fried D, Glena RE, Featherstone JD, Seka W. PMID: 9041504.
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