Daniel Fried, PhD

Title(s)Professor, Preventive & Restor Dent Sci
SchoolSchool of Dentistry
Address707 Parnassus Ave
San Francisco CA 94143
Phone415-502-6641
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    Collapse Research 
    Collapse Research Activities and Funding
    Imaging Dental Caries with SWIR Light
    NIH R01DE028295Aug 1, 2019 - Apr 30, 2024
    Role: Principal Investigator
    Optical Methods for Lesion Activity Assessment
    NIH R01DE027335Sep 1, 2018 - Jun 30, 2023
    Role: Principal Investigator
    Selective Ablation of Dental Caries and Composites
    NIH R01DE019631Sep 1, 2009 - Mar 31, 2019
    Role: Principal Investigator
    Clinical Assessment of Tooth Demineralization & Remineralization with PS-OCT
    NIH R01DE017869Aug 15, 2006 - Jul 31, 2016
    Role: Principal Investigator
    Early Caries Detection with Near-IR Light
    NIH R01DE014698Aug 1, 2002 - Apr 30, 2018
    Role: Principal Investigator
    Laser Ablation of Dental Hard Tissues
    NIH R01DE014554Jun 1, 2002 - May 31, 2008
    Role: Principal Investigator
    MULTIPURPOSE CO2 TEA LASER FOR DENTAL APPLICATIONS
    NIH R41DE012971Aug 1, 2000 - Jul 31, 2001
    Role: Principal Investigator
    IR LASER ABLATION OF DENTAL HARD TISSUE
    NIH R29DE012091Aug 1, 1997 - May 31, 2003
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Evaluating interproximal and occlusal lesion severity with a dual SWIR transillumination/reflectance probe. Proc SPIE Int Soc Opt Eng. 2022 Jan-Feb; 11942. Zhu Y, Fried D. PMID: 35444360; PMCID: PMC9017391.
      View in: PubMed   Mentions:
    2. Use of SWIR dehydration and OCT to assess the complete arrest of simulated incipient caries lesions. Proc SPIE Int Soc Opt Eng. 2022 Jan-Feb; 11942. Chang NY, Tressel J, Kashirtsev F, Fried D. PMID: 35444361; PMCID: PMC9017390.
      View in: PubMed   Mentions:
    3. Caries inhibition of simulated active caries lesions with CO2 laser irradiation and fluoride. Proc SPIE Int Soc Opt Eng. 2022 Jan-Feb; 11942. Tressel J, Kashirtsev F, Cheung K, Simon J, Fried D. PMID: 35450400; PMCID: PMC9020385.
      View in: PubMed   Mentions:
    4. Assessing lesion activity of secondary lesions on extracted teeth by thermal dehydration measurement and optical coherence tomography. Proc SPIE Int Soc Opt Eng. 2022 Jan-Feb; 11942. Chang NN, Dillas T, Fried D. PMID: 35450401; PMCID: PMC9020384.
      View in: PubMed   Mentions:
    5. Dehydration imaging of dental fluorosis at 1950 nm. Proc SPIE Int Soc Opt Eng. 2022 Jan-Feb; 11942. Kashirtsev F, Tressel J, Fried D. PMID: 35440838; PMCID: PMC9014758.
      View in: PubMed   Mentions:
    6. Measurement of the Depth of Lesions on Proximal Surfaces with SWIR Multispectral Transillumination and Reflectance Imaging. Diagnostics (Basel). 2022 Feb 26; 12(3). Zhu Y, Fried D. PMID: 35328150; PMCID: PMC8947190.
      View in: PubMed   Mentions:
    7. Monitoring silver diamine fluoride application with optical coherence tomography and thermal imaging: An in vitro proof of concept study. Lasers Surg Med. 2022 Feb 25. Abdelaziz M, Yang V, Chang NN, Darling C, Fried W, Seto J, Fried D. PMID: 35212407.
      View in: PubMed   Mentions:
    8. High contrast imaging of dental fluorosis in the short wavelength infrared. J Biophotonics. 2021 10; 14(10):e202100145. Kashirtsev F, Tressel J, Simon JC, Fried D. PMID: 34302430.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Cross-polarization optical coherence tomographic assessment of in situ simulated erosive tooth wear. J Biophotonics. 2021 09; 14(9):e202100090. Romero MJRH, Bezerra SJC, Fried D, Yang V, Lippert F, Eckert GJ, Zero DT, Hara AT. PMID: 34105881; PMCID: PMC8448929.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Computer-Controlled CO2 Laser Ablation System for Cone-beam Computed Tomography and Digital Image Guided Endodontic Access: A Pilot Study. J Endod. 2021 Sep; 47(9):1445-1452. Simon JC, Kwok JW, Vinculado F, Fried D. PMID: 34119563; PMCID: PMC8867881.
      View in: PubMed   Mentions:    Fields:    
    11. Dynamic SWIR imaging near the 1950-nm water absorption band for caries lesion diagnosis. J Biomed Opt. 2021 05; 26(5). Tressel JT, Abdelaziz M, Fried D. PMID: 34032036; PMCID: PMC8144227.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. High contrast reflectance imaging at 1950 nm for the assessment of lesion activity on extracted teeth. Proc SPIE Int Soc Opt Eng. 2021 Mar; 11627. Tressel J, Abdelaziz M, Fried D. PMID: 33762796; PMCID: PMC7986894.
      View in: PubMed   Mentions: 1  
    13. Infrared imaging confirms the role of the transparent surface zone in arresting dental caries. Proc SPIE Int Soc Opt Eng. 2021 Mar; 11627. Liu H, Chang NY, Gao W, Fried D. PMID: 33767521; PMCID: PMC7989780.
      View in: PubMed   Mentions: 1  
    14. Imaging dental fluorosis at SWIR wavelengths from 1300 to 2000-nm. Proc SPIE Int Soc Opt Eng. 2021 Mar; 11627. Kashirtsev F, Simon JC, Fried D. PMID: 33767522; PMCID: PMC7989784.
      View in: PubMed   Mentions:
    15. Multispectral SWIR images of the pulp-chamber of posterior teeth in vitro. Proc SPIE Int Soc Opt Eng. 2021 Mar; 11627. Simon JC, Mogire EO, Yun SY, Fried D. PMID: 33776188; PMCID: PMC7993031.
      View in: PubMed   Mentions:
    16. Compact in vivo handheld dual SWIR transillumination/reflectance imaging system for the detection of proximal and occlusal lesions. Proc SPIE Int Soc Opt Eng. 2021 Mar; 11627. Zhu Y, Simon J, Ng C, Fried D. PMID: 33790493; PMCID: PMC8008980.
      View in: PubMed   Mentions:
    17. High Contrast Reflectance Imaging of Enamel Demineralization and Remineralization at 1950-nm for the Assessment of Lesion Activity. Lasers Surg Med. 2021 09; 53(7):968-977. Fried WA, Abdelaziz M, Darling CL, Fried D. PMID: 33442896; PMCID: PMC8275669.
      View in: PubMed   Mentions: 3     Fields:    
    18. Dual short wavelength infrared transillumination/reflectance mode imaging for caries detection. J Biomed Opt. 2021 01; 26(4). Zhu Y, Abdelaziz M, Simon J, Le O, Fried D. PMID: 33515220; PMCID: PMC7844424.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Thermal Imaging of Root Caries In Vivo. J Dent Res. 2020 12; 99(13):1502-1508. Yang V, Zhu Y, Curtis D, Le O, Chang NYN, Fried WA, Simon JC, Banan P, Darling CL, Fried D. PMID: 32866422; PMCID: PMC7684841.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    20. SWIR, Thermal and CP-OCT imaging probes for the in vivo assessment of the activity of root caries lesions. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Chang NY, Zhu Y, Curtis D, Le O, Yang V, Fried WA, Simon JC, Banan P, Darling CL, Fried D. PMID: 33612912; PMCID: PMC7894617.
      View in: PubMed   Mentions: 1  
    21. A dual handheld SWIR transillumination/reflectance probe for imaging lesions on tooth occlusal and proximal surfaces. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Zhu Y, Chang NY, Fried WA, Yang V, Fried D. PMID: 33603261; PMCID: PMC7888982.
      View in: PubMed   Mentions: 1  
    22. Optical Coherence Tomography (OCT) for the evaluation of internal adaptation of class V resin restorations on Dentin. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Abdelaziz M, Zuluaga AF, Betancourt F, Fried D, Krejci I, Bortolotto T. PMID: 33603262; PMCID: PMC7888983.
      View in: PubMed   Mentions:
    23. A SWIR imaging handpiece for the clinical assessment of lesion activity via dehydration. Preclinical Assessment. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Fried WA, Zhu Y, Yang V, Chang NY, Fried D. PMID: 32194294; PMCID: PMC7081727.
      View in: PubMed   Mentions:
    24. In vivo spectral guided removal of composite from tooth surfaces with a CO2 laser. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Simon JC, Choi JH, Jang A, Fried D. PMID: 32161428; PMCID: PMC7065526.
      View in: PubMed   Mentions:
    25. A thermal imaging handpiece for the clinical assessment of lesion activity on root surfaces via dehydration. Proc SPIE Int Soc Opt Eng. 2020 Feb; 11217. Yang VB, Chang NY, Fried D. PMID: 32231402; PMCID: PMC7105143.
      View in: PubMed   Mentions: 1  
    26. Enhancing the detection of proximal cavities on near infrared transillumination images with Indocyanine Green (ICG) as a contrast medium: In vitro proof of concept studies. J Dent. 2019 12; 91:103222. Abdelaziz M, Krejci I, Fried D. PMID: 31682898; PMCID: PMC6885130.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    27. Measurement of the shrinkage of natural and simulated lesions on root surfaces using CP-OCT. J Dent. 2019 11; 90:103213. Yang V, Fried D. PMID: 31622647; PMCID: PMC6905190.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    28. In vitro longitudinal evaluation of enamel wear by cross-polarization optical coherence tomography. Dent Mater. 2019 10; 35(10):1464-1470. Alghilan MA, Lippert F, Platt JA, Eckert GJ, González-Cabezas C, Fried D, Hara AT. PMID: 31395451.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    29. Image-Guided Ablation of Dental Calculus From Root Surfaces Using a DPSS Er:YAG Laser. Lasers Surg Med. 2020 03; 52(3):247-258. Fried WA, Chan KH, Darling CL, Curtis DA, Fried D. PMID: 31236996; PMCID: PMC8880256.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Near-infrared imaging of demineralization on the occlusal surfaces of teeth without the interference of stains. J Biomed Opt. 2019 03; 24(3):1-8. Ng C, Almaz E, Simon J, Fried D, Darling C. PMID: 30834721; PMCID: PMC6975183.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    31. The Relationship of Dehydration Rate and Transparent Surface Layer Thickness for Coronal Lesions on Extracted Teeth. Proc SPIE Int Soc Opt Eng. 2019 Feb; 10857. Chang NN, Abdelaziz M, Fried D. PMID: 30918416; PMCID: PMC6433154.
      View in: PubMed   Mentions:
    32. An appliance for monitoring the shrinkage of root caries with OCT. Proc SPIE Int Soc Opt Eng. 2019 Feb; 10857. Yang VB, Fried D. PMID: 30918417; PMCID: PMC6433155.
      View in: PubMed   Mentions: 1  
    33. Selective removal of dental calculus with a diode-pumped Er:YAG laser. Proc SPIE Int Soc Opt Eng. 2019 Feb; 10857. Fried WA, Chan KH, Darling CL, Fried D. PMID: 31000908; PMCID: PMC6467515.
      View in: PubMed   Mentions: 1  
    34. The contrast of demineralization on tooth occlusal surfaces from 405 to 1950-nm with varying depth. Proc SPIE Int Soc Opt Eng. 2019 Feb; 10857. Mohajerani N, Chan KH, Yang VB, Fried D, Darling CL. PMID: 30923417; PMCID: PMC6434518.
      View in: PubMed   Mentions:
    35. Image guided laser ablation of demineralization from root surfaces. Proc SPIE Int Soc Opt Eng. 2019 Feb; 10857. Dhillon N, Chan KH, Yang VB, Fried D. PMID: 31007338; PMCID: PMC6469870.
      View in: PubMed   Mentions:
    36. Impact of surface micromorphology and demineralization severity on enamel loss measurements by cross-polarization optical coherence tomography. J Dent. 2019 02; 81:52-58. Alghilan MA, Lippert F, Platt JA, Eckert GJ, González-Cabezas C, Fried D, Hara AT. PMID: 30582963.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    37. Use of a DPSS Er:YAG laser for the selective removal of composite from tooth surfaces. Biomed Opt Express. 2018 Oct 01; 9(10):5026-5036. Fried WA, Chan KH, Darling CL, Fried D. PMID: 30319919; PMCID: PMC6179409.
      View in: PubMed   Mentions: 4  
    38. Selective ablation of dental caries using coaxial Co2 (9.3-μm) and near-IR (1880-nm) lasers. Lasers Surg Med. 2019 02; 51(2):176-184. Chan KH, Fried D. PMID: 30024032; PMCID: PMC8867882.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    39. Cross-polarization reflectance imaging of root caries and dental calculus on extracted teeth at wavelengths from 400 to 2350 nm. J Biophotonics. 2018 11; 11(11):e201800113. Yang VB, Curtis DA, Fried D. PMID: 29952066.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    40. Optical Coherence Tomography. Dent Clin North Am. 2018 Jul; 62(3):421-434. Katkar RA, Tadinada SA, Amaechi BT, Fried D. PMID: 29903559.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    41. Fluorescence and Near-Infrared Light Transillumination. Dent Clin North Am. 2018 Jul; 62(3):435-452. Amaechi BT, Owosho AA, Fried D. PMID: 29903560.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    42. Multispectral cross-polarization reflectance measurements suggest high contrast of demineralization on tooth surfaces at wavelengths beyond 1300 nm due to reduced light scattering in sound enamel. J Biomed Opt. 2018 06; 23(6):1-4. Chan KH, Fried D. PMID: 29877068; PMCID: PMC5989821.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    43. Multispectral near-infrared reflectance and transillumination imaging of occlusal carious lesions: Variation in lesion contrast with lesion depth. Proc SPIE Int Soc Opt Eng. 2018 Jan-Feb; 10473. Simon JC, Curtis DA, Darling CL, Fried D. PMID: 29497229; PMCID: PMC5827960.
      View in: PubMed   Mentions: 4  
    44. Image-guided Removal of Interproximal Lesions with a CO2 Laser. Proc SPIE Int Soc Opt Eng. 2018 Jan-Feb; 10473. Ngo A, Chan KH, Le O, Simon JC, Fried D. PMID: 29497230; PMCID: PMC5827963.
      View in: PubMed   Mentions: 1  
    45. SWIR reflectance imaging of demineralization on the occlusal surfaces of teeth beyond 1700 nm. Proc SPIE Int Soc Opt Eng. 2018 Jan-Feb; 10473. Ng C, Simon JC, Fried D, Darling CL. PMID: 30686852; PMCID: PMC6345412.
      View in: PubMed   Mentions: 1  
    46. Lesion Dehydration Rate Changes with the Surface Layer Thickness during Enamel Remineralization. Proc SPIE Int Soc Opt Eng. 2018 Feb; 10473. Chang NN, Jew JM, Fried D. PMID: 30034077; PMCID: PMC6053078.
      View in: PubMed   Mentions: 4  
    47. Selective Ablation of Carious Lesions using an Integrated Near-IR Imaging System and a Novel 9.3-µm CO2 Laser. Proc SPIE Int Soc Opt Eng. 2018 Feb; 10473. Chan KH, Fried NM, Fried D. PMID: 30034078; PMCID: PMC6054456.
      View in: PubMed   Mentions: 4  
    48. Influence of multi-wavelength laser irradiation of enamel and dentin surfaces at 0.355, 2.94, and 9.4 μm on surface morphology, permeability, and acid resistance. Lasers Surg Med. 2017 12; 49(10):913-927. Chang NN, Jew JM, Simon JC, Chen KH, Lee RC, Fried WA, Cho J, Darling CL, Fried D. PMID: 28699676; PMCID: PMC5734993.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    49. Automated ablation of dental composite using an IR pulsed laser coupled to a plume emission spectral feedback system. Lasers Surg Med. 2017 09; 49(7):658-665. Jang AT, Chan KH, Fried D. PMID: 28467687; PMCID: PMC5568963.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    50. Near-IR and CP-OCT imaging of suspected occlusal caries lesions. Lasers Surg Med. 2017 03; 49(3):215-224. Simon JC, Kang H, Staninec M, Jang AT, Chan KH, Darling CL, Lee RC, Fried D. PMID: 28339115; PMCID: PMC5367963.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    51. Influence of a pulsed CO2 laser operating at 9.4  μm on the surface morphology, reflectivity, and acid resistance of dental enamel below the threshold for melting. J Biomed Opt. 2017 02 01; 22(2):28001. Kim JW, Lee R, Chan KH, Jew JM, Fried D. PMID: 28145558; PMCID: PMC5286555.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    52. Optical changes of dentin in the near-IR as a function of mineral content. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Berg RA, Simon JC, Fried D, Darling CL. PMID: 28450756; PMCID: PMC5404412.
      View in: PubMed   Mentions:
    53. Automated ablation of dental composite using an IR pulsed laser coupled to a plume emission spectral feedback system. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Jang AT, Chan KH, Fried D. PMID: 28479654; PMCID: PMC5416812.
      View in: PubMed   Mentions:
    54. High-Contrast Reflectance Imaging of Composite Restorations Color-Matched to Tooth Structure at 1000-2300-nm. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Fried WA, Simon JC, Darling CL, Le O, Fried D. PMID: 28626287; PMCID: PMC5473514.
      View in: PubMed   Mentions:
    55. Influence of Multi-Wavelength Laser Irradiation of Enamel and Dentin Surfaces on Surface Morphology and Permeability. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Chang NN, Jew J, Simon JC, Chan KH, Lee RC, Fried WA, Cho J, Darling CL, Fried D. PMID: 28680191; PMCID: PMC5495473.
      View in: PubMed   Mentions: 2  
    56. Assessment of cavitation in artificial approximal dental lesions with near-IR imaging. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Simon JC, Darling CL, Fried D. PMID: 28626283; PMCID: PMC5473505.
      View in: PubMed   Mentions: 4  
    57. Near-infrared imaging of enamel hypomineralization due to developmental defects. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Lee RC, Jang A, Fried D. PMID: 28626284; PMCID: PMC5473506.
      View in: PubMed   Mentions:
    58. Selective Laser Ablation of Carious Lesions using Simultaneous Scanned Near-IR Diode and CO2 Lasers. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Chan KH, Fried D. PMID: 28626285; PMCID: PMC5473510.
      View in: PubMed   Mentions: 1  
    59. Synergistic effect of fluoride and laser irradiation for the inhibition of the demineralization of dental enamel. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Lee R, Chan KH, Jew J, Simon JC, Fried D. PMID: 28626286; PMCID: PMC5473511.
      View in: PubMed   Mentions: 4  
    60. Assessment of radicular dentin permeability after irradiation with CO2 laser and endodontic irrigation treatments with thermal imaging. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Cho H, Lee RC, Chan KH, Fried D. PMID: 28626288; PMCID: PMC5473517.
      View in: PubMed   Mentions:
    61. Selective removal of natural caries lesions from dentin and tooth occlusal surfaces using a diode-pumped Er:YAG laser. Proc SPIE Int Soc Opt Eng. 2017 Jan 28; 10044. Jew J, Chan KH, Darling CL, Fried D. PMID: 28450757; PMCID: PMC5404413.
      View in: PubMed   Mentions: 3  
    62. Use of an optical clearing agent to enhance the visibility of subsurface structures and lesions from tooth occlusal surfaces. J Biomed Opt. 2016 Aug; 21(8):081206. Kang H, Darling CL, Fried D. PMID: 27071709; PMCID: PMC4828753.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    63. Enamel Thickness Determination by Optical Coherence Tomography: In vitro Validation. Caries Res. 2016; 50(4):400-6. Algarni A, Kang H, Fried D, Eckert GJ, Hara AT. PMID: 27454764.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    64. Near-IR transillumination and reflectance imaging at 1,300 nm and 1,500-1,700 nm for in vivo caries detection. Lasers Surg Med. 2016 11; 48(9):828-836. Simon JC, Lucas SA, Staninec M, Tom H, Chan KH, Darling CL, Cozin MJ, Lee RC, Fried D. PMID: 27389018; PMCID: PMC5495016.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    65. Activity assessment of root caries lesions with thermal and near-IR imaging methods. J Biophotonics. 2017 Mar; 10(3):433-445. Lee RC, Darling CL, Staninec M, Ragadio A, Fried D. PMID: 27060450; PMCID: PMC5053863.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    66. Infrared Methods for Assessment of the Activity of Natural Enamel Caries Lesions. IEEE J Sel Top Quantum Electron. 2016 May-Jun; 22(3). Lee RC, Staninec M, Le O, Fried D. PMID: 27642246; PMCID: PMC5021449.
      View in: PubMed   Mentions: 15  
    67. Clinical monitoring of smooth surface enamel lesions using CP-OCT during nonsurgical intervention. Lasers Surg Med. 2016 12; 48(10):915-923. Chan KH, Tom H, Lee RC, Kang H, Simon JC, Staninec M, Darling CL, Pelzner RB, Fried D. PMID: 26955902; PMCID: PMC5495013.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    68. Selective removal of esthetic composite restorations with spectral guided laser ablation. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. Yi I, Chan KH, Tsuji GH, Staninec M, Darling CL, Fried D. PMID: 26997742; PMCID: PMC4793932.
      View in: PubMed   Mentions:
    69. A system for simultaneous near-infrared reflectance and transillumination imaging of occlusal carious lesions. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. Simon JC, Darling CL, Fried D. PMID: 27006524; PMCID: PMC4799999.
      View in: PubMed   Mentions: 3  
    70. Influence of stains on lesion contrast in the pits and fissures of tooth occlusal surfaces from 800-1600-nm. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. Almaz EC, Simon JC, Fried D, Darling CL. PMID: 26997740; PMCID: PMC4793930.
      View in: PubMed   Mentions: 9  
    71. Assessment of simulated lesions on primary teeth with near-infrared imaging. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. Tam W, Lee RC, Lin B, Simon JC, Fried D. PMID: 26997743; PMCID: PMC4793935.
      View in: PubMed   Mentions:
    72. A new sealed RF-excited CO2 laser for enamel ablation operating at 9.4-μm with a pulse duration of 26-μs. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. Chan KH, Jew JM, Fried D. PMID: 27006521; PMCID: PMC4799993.
      View in: PubMed   Mentions:
    73. Assessment of remineralized dentin lesions with thermal and near-infrared reflectance imaging. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. Lee RC, Darling CL, Fried D. PMID: 27006522; PMCID: PMC4799994.
      View in: PubMed   Mentions: 4  
    74. Evaluation of enamel surface modification using PS-OCT after laser treatment to increase resistance to demineralization. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. Kim JW, Chan KH, Fried D. PMID: 27006523; PMCID: PMC4799996.
      View in: PubMed   Mentions: 5  
    75. Enhancement of OCT images with vinyl polysiloxane (VPS). Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. Kang H, Darling CL, Fried D. PMID: 27011417; PMCID: PMC4801027.
      View in: PubMed   Mentions: 1  
    76. Selective removal of dental composite with a diode-pumped Er:YAG laser. Proc SPIE Int Soc Opt Eng. 2016 Feb 13; 9692. Fried WA, Chan KH, Darling CL, Fried D. PMID: 26997741; PMCID: PMC4793931.
      View in: PubMed   Mentions: 2  
    77. Near-infrared imaging of secondary caries lesions around composite restorations at wavelengths from 1300-1700-nm. Dent Mater. 2016 Apr; 32(4):587-95. Simon JC, A Lucas S, Lee RC, Darling CL, Staninec M, Vaderhobli R, Pelzner R, Fried D. PMID: 26876234; PMCID: PMC4801720.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    78. Near-IR image-guided laser ablation of demineralization on tooth occlusal surfaces. Lasers Surg Med. 2016 Jan; 48(1):52-61. Tom H, Chan KH, Darling CL, Fried D. PMID: 26763111; PMCID: PMC4779057.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    79. Assessment of remineralization via measurement of dehydration rates with thermal and near-IR reflectance imaging. J Dent. 2015 Aug; 43(8):1032-42. Lee RC, Darling CL, Fried D. PMID: 25862275; PMCID: PMC4509858.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    80. Enhanced detection of dentinal lesions in OCT images using the RKT transformation. Proc SPIE Int Soc Opt Eng. 2015 Feb 24; 9306. Kang H, Darling CL, Tom H, Fried D. PMID: 25914493; PMCID: PMC4405665.
      View in: PubMed   Mentions: 4  
    81. In vitro near-infrared imaging of natural secondary caries. Proc SPIE Int Soc Opt Eng. 2015 Feb 24; 9306. Simon JC, Lucas S, Lee R, Darling CL, Staninec M, Vanderhobli R, Pelzner R, Fried D. PMID: 25914495; PMCID: PMC4405668.
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    169. Measurement of the severity of natural smooth surface (interproximal) caries lesions with polarization sensitive optical coherence tomography. Lasers Surg Med. 2005 Jul; 37(1):78-88. Ngaotheppitak P, Darling CL, Fried D. PMID: 15889402.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    170. Imaging of occlusal dental caries (decay) with near-IR light at 1310-nm. Opt Express. 2005 Jan 24; 13(2):573-82. Bühler C, Ngaotheppitak P, Fried D. PMID: 19488387.
      View in: PubMed   Mentions: 66     Fields:    
    171. Selective removal of composite sealants with near-ultraviolet laser pulses of nanosecond duration. J Biomed Opt. 2005 Jan-Feb; 10(1):14001. Louie TM, Jones RS, Sarma AV, Fried D. PMID: 15847582.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    172. Transmission of Q-switched erbium:YSGG (lambda=2.79 microm) and erbium:YAG (lambda=2.94 microm) laser radiation through germanium oxide and sapphire optical fibres at high pulse energies. Lasers Med Sci. 2004; 19(3):155-60. Fried NM, Yang Y, Chaney CA, Fried D. PMID: 15645320.
      View in: PubMed   Mentions: 2     Fields:    
    173. Imaging artificial caries under composite sealants and restorations. J Biomed Opt. 2004 Nov-Dec; 9(6):1297-304. Jones RS, Staninec M, Fried D. PMID: 15568951.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    174. Pulpal safety of 9.6 microm TEA CO2 laser used for caries prevention. Lasers Surg Med. 2004; 35(2):104-10. Goodis HE, Fried D, Gansky S, Rechmann P, Featherstone JD. PMID: 15334612.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    175. Peripheral thermal and mechanical damage to dentin with microsecond and sub-microsecond 9.6 microm, 2.79 microm, and 0.355 microm laser pulses. Lasers Surg Med. 2004; 35(3):214-28. Dela Rosa A, Sarma AV, Le CQ, Jones RS, Fried D. PMID: 15389737.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    176. Selective targeting of protein, water, and mineral in dentin using UV and IR pulse lasers: the effect on the bond strength to composite restorative materials. Lasers Surg Med. 2004; 35(4):245-53. Sheth KK, Staninec M, Sarma AV, Fried D. PMID: 15493023.
      View in: PubMed   Mentions: 14     Fields:    
    177. Near-infrared transillumination at 1310-nm for the imaging of early dental decay. Opt Express. 2003 Sep 08; 11(18):2259-65. Jones R, Huynh G, Jones G, Fried D. PMID: 19466117.
      View in: PubMed   Mentions: 60     Fields:    
    178. Irradiation of dental enamel with Q-switched lambda = 355-nm laser pulses: surface morphology, fluoride adsorption, and adhesion to composite resin. Lasers Surg Med. 2003; 32(4):310-7. Wheeler CR, Fried D, Featherstone JD, Watanabe LG, Le CQ. PMID: 12696100.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    179. Influence of an optically thick water layer on the bond-strength of composite resin to dental enamel after IR laser ablation. Lasers Surg Med. 2003; 33(4):264-9. Staninec M, Xie J, Le CQ, Fried D. PMID: 14571452.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    180. Imaging caries lesions and lesion progression with polarization sensitive optical coherence tomography. J Biomed Opt. 2002 Oct; 7(4):618-27. Fried D, Xie J, Shafi S, Featherstone JD, Breunig TM, Le C. PMID: 12421130.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansAnimals
    181. Thermal and chemical modification of dentin by 9-11-microm CO2 laser pulses of 5-100-micros duration. Lasers Surg Med. 2002; 31(4):275-82. Fried D, Zuerlein MJ, Le CQ, Featherstone JD. PMID: 12355574.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    182. Selective ablation of surface enamel caries with a pulsed Nd:YAG dental laser. Lasers Surg Med. 2002; 30(5):342-50. Harris DM, White JM, Goodis H, Arcoria CJ, Simon J, Carpenter WM, Fried D, Burkart J, Yessik M, Myers T. PMID: 12116326.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    183. Selective removal of residual composite from dental enamel surfaces using the third harmonic of a Q-switched Nd:YAG laser. Lasers Surg Med. 2002; 30(3):240-5. Alexander R, Xie J, Fried D. PMID: 11891745.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    184. Mechanism of water augmentation during IR laser ablation of dental enamel. Lasers Surg Med. 2002; 31(3):186-93. Fried D, Ashouri N, Breunig T, Shori R. PMID: 12224092.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    185. Dental hard tissue modification and removal using sealed transverse excited atmospheric-pressure lasers operating at lambda=9.6 and 10.6 microm. J Biomed Opt. 2001 Apr; 6(2):231-8. Fried D, Ragadio J, Akrivou M, Featherstone JD, Murray MW, Dickenson KM. PMID: 11375734.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    186. Residual heat deposition in dental enamel during IR laser ablation at 2.79, 2.94, 9.6, and 10.6 microm. Lasers Surg Med. 2001; 29(3):221-9. Fried D, Ragadio J, Champion A. PMID: 11573223.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    187. Selective ablation of orthodontic composite by using sub-microsecond IR laser pulses with optical feedback. Lasers Surg Med. 2000; 27(2):103-10. Dumore T, Fried D. PMID: 10960816.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    188. Modeling the modification depth of carbon dioxide laser-treated dental enamel. Lasers Surg Med. 1999; 25(4):335-47. Zuerlein MJ, Fried D, Featherstone JD. PMID: 10534750.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    189. CO2 laser inhibitor of artificial caries-like lesion progression in dental enamel. J Dent Res. 1998 Jun; 77(6):1397-403. Featherstone JD, Barrett-Vespone NA, Fried D, Kantorowitz Z, Seka W. PMID: 9649168.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    190. Permanent and transient changes in the reflectance of CO2 laser-irradiated dental hard tissues at lambda = 9.3, 9.6, 10.3, and 10.6 microns and at fluences of 1-20 J/cm2. Lasers Surg Med. 1997; 20(1):22-31. Fried D, Glena RE, Featherstone JD, Seka W. PMID: 9041504.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
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