Susan Miller, PhD
|School||UCSF School of Pharmacy|
|Address||600 16th Street|
San Francisco CA 94158
|1974||National Merit Scholar|
|University of Missouri ||1974||Curator's Scholar Award|
|University of Missouri||1977||Phi Lambda Upsilon|
|University of Missouri||1978||Phi Beta Kappa|
|University of California||1984||Sigma Xi|
Broadly, we use a variety of biochemical and biophysical tools to investigate protein structure/function questions spanning the range of elucidating novel aspects of catalysis in individual enzymes to understanding the interactions of proteins within a pathway and how mutations influence flux through the pathway. Current work is focused on understanding how key enzymes and transport proteins of bacterial mercury detoxification pathways work individually, with each other, and with other host cell proteins to rapidly remove the toxic threat of organomercurials (such as Methyl-Hg) and mercuric ions from their environment.
Enzyme mechanisms emphasizing redox systems, protein-protein interactions, and structure-function relationships of mechanisms of regulation and catalysis.
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