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TPT sulfonate, a single, oral dose schistosomicidal prodrug: In vivo efficacy, disposition and metabolic profiling. Int J Parasitol Drugs Drug Resist. 2018 12; 8(3):571-586.
Wolfe AR, Neitz RJ, Burlingame M, Suzuki BM, Lim KC, Scheideler M, Nelson DL, Benet LZ, Caffrey CR. PMID: 30503203; PMCID: PMC6287543.
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5 Fields:
Translation:
Animals
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Identification and Optimization of Thienopyridine Carboxamides as Inhibitors of HIV Regulatory Complexes. Antimicrob Agents Chemother. 2017 07; 61(7).
Nakamura RL, Burlingame MA, Yang S, Crosby DC, Talbot DJ, Chui K, Frankel AD, Renslo AR. PMID: 28416550; PMCID: PMC5487668.
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2 Fields:
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Capture of micrococcin biosynthetic intermediates reveals C-terminal processing as an obligatory step for in vivo maturation. Proc Natl Acad Sci U S A. 2016 11 01; 113(44):12450-12455.
Bewley KD, Bennallack PR, Burlingame MA, Robison RA, Griffitts JS, Miller SM. PMID: 27791142; PMCID: PMC5098666.
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7 Fields:
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Cells
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Reconstitution and Minimization of a Micrococcin Biosynthetic Pathway in Bacillus subtilis. J Bacteriol. 2016 09 15; 198(18):2431-8.
Bennallack PR, Bewley KD, Burlingame MA, Robison RA, Miller SM, Griffitts JS. PMID: 27381911; PMCID: PMC4999933.
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PubMed Mentions:
8 Fields:
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Cells
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Simple one-pot synthesis of disulfide fragments for use in disulfide-exchange screening. ACS Comb Sci. 2011 May 09; 13(3):205-8.
Burlingame MA, Tom CT, Renslo AR. PMID: 21500860.
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7 Fields:
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Cells
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Turning a protein kinase on or off from a single allosteric site via disulfide trapping. Proc Natl Acad Sci U S A. 2011 Apr 12; 108(15):6056-61.
Sadowsky JD, Burlingame MA, Wolan DW, McClendon CL, Jacobson MP, Wells JA. PMID: 21430264; PMCID: PMC3076885.
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54 Fields:
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Cells
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Structure-activity relationships of 9-substituted-9-dihydroerythromycin-based motilin agonists: optimizing for potency and safety. J Med Chem. 2009 Nov 12; 52(21):6851-9.
Shaw SJ, Chen Y, Zheng H, Fu H, Burlingame MA, Marquez S, Li Y, Claypool M, Carreras CW, Crumb W, Hardy DJ, Myles DC, Liu Y. PMID: 19821563.
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PubMed Mentions:
1 Fields:
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HumansAnimalsCells
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Preparation of erythromycin analogs having functional groups at C-15. J Antibiot (Tokyo). 2006 Jul; 59(7):392-401.
Ashley GW, Burlingame M, Desai R, Fu H, Leaf T, Licari PJ, Tran C, Abbanat D, Bush K, Macielag M. PMID: 17025015.
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PubMed Mentions:
8 Fields:
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Cells
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A series of 23,24-dihydrodiscodermolide analogues with simplified lactone regions. Bioorg Med Chem Lett. 2006 Apr 01; 16(7):1961-4.
Shaw SJ, Sundermann KF, Burlingame MA, Zhang D, Petryka J, Myles DC. PMID: 16413186.
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1 Fields:
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HumansCells
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Toward understanding how the lactone moiety of discodermolide affects activity. J Am Chem Soc. 2005 May 11; 127(18):6532-3.
Shaw SJ, Sundermann KF, Burlingame MA, Myles DC, Freeze BS, Xian M, Brouard I, Smith AB. PMID: 15869264.
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11 Fields:
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HumansCells
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Design, synthesis, and evaluation of analogues of (+)-14-normethyldiscodermolide. Org Lett. 2005 Jan 20; 7(2):315-8.
Smith AB, Freeze BS, Lamarche MJ, Hirose T, Brouard I, Xian M, Sundermann KF, Shaw SJ, Burlingame MA, Horwitz SB, Myles DC. PMID: 15646986.
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2 Fields:
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HumansCells
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Design, synthesis, and evaluation of carbamate-substituted analogues of (+)-discodermolide. Org Lett. 2005 Jan 20; 7(2):311-4.
Smith AB, Freeze BS, Lamarche MJ, Hirose T, Brouard I, Rucker PV, Xian M, Sundermann KF, Shaw SJ, Burlingame MA, Horwitz SB, Myles DC. PMID: 15646985.
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6 Fields:
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HumansCells
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Design, synthesis and cytotoxicity of 7-deoxy aryl discodermolide analogues. Bioorg Med Chem Lett. 2004 May 03; 14(9):2335-8.
Burlingame MA, Shaw SJ, Sundermann KF, Zhang D, Petryka J, Mendoza E, Liu F, Myles DC, LaMarche MJ, Hirose T, Scott Freeze B, Smith AB. PMID: 15081036.
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PubMed Mentions:
4 Fields:
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HumansCells
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Saccharopolyspora erythraea-catalyzed bioconversion of 6-deoxyerythronolide B analogs for production of novel erythromycins. J Biotechnol. 2002 Jan 18; 92(3):217-28.
Carreras C, Frykman S, Ou S, Cadapan L, Zavala S, Woo E, Leaf T, Carney J, Burlingame M, Patel S, Ashley G, Licari P. PMID: 11689246.
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PubMed Mentions:
4 Fields:
Translation:
Cells