Dr. Rotenstein is a primary care physician, researcher and healthcare leader whose work focuses on ambulatory care delivery, physician wellbeing, gender issues in medicine, and the intersection of the electronic health record with these issues.

She is an Assistant Professor and Medical Director of Ambulatory Quality and Safety at UCSF Health. She additionally serves as the inaugural director of the Center to Advance Digital Physician Practice Transformation at UCSF (ADAPT) and Director of the Center for Physician Experience and Practice Excellence, which is jointly run across UCSF and Brigham and Women's Hospital. She was named a 2022 Modern Healthcare Top 25 Emerging Leader, the 2022 New England Region SGIM Investigator of the Year, and a 2021 STAT Wunderkind.

Dr. Rotenstein's research on physician and trainee mental health, published in JAMA, JAMA Health Forum, and the Journal of General Internal Medicine has fostered increased awareness of the epidemic of depression and burnout in medical students and physicians and catalyzed action to address this public health burden. Her research on the electronic health record (EHR), published in JAMA Internal Medicine, JAMA Network Open, and JAMIA, have deepened our understanding of the role of the EHR in physician experience. She is a nationally recognized expert on gender issues in medicine, with her research and writing on this topic featured in the New England Journal of Medicine, the Harvard Business Review, and JAMA Internal Medicine.

Dr. Rotenstein currently is establishing and leading ambulatory quality efforts across the UCSF Health system in her role as Medical Director of Ambulatory Quality and Safety. She additionally leads quality and electronic inbox optimization efforts for the UCSF Department of Medicine. Previously, as Medical Director of Population Health at Brigham and Women's Hospital, she led population health and collaborative care initiatives across Brigham Health's primary care practices, which care for 150,000 patients. Prior to that, she led faculty development and wellbeing, population health, and job doability efforts for the Brigham and Women's Physicians Organization.