Chiung-Yu Huang, PhD

InstitutionUniversity of California San Francisco
DepartmentEpidemiology & Biostatistics
Address550 16th. Street
San Francisco CA 94158
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    Collapse Biography 
    Collapse Education and Training
    National Tsing-Hua University , TaiwanBS05/1994Mathematics
    National Tsing-Hua University, TaiwanMS05/1996Mathematics
    Johns Hopkins University, BaltimorePhD05/2002Biostatistics
    Collapse Awards and Honors
    Department of Biostatistics, Johns Hopkins University, Baltimore, MD2002Margaret Merrell Award
    University of Minnesota, Minneapolis, MN2003Grant-in-Aid of Research, Artistry, and Scholarship
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD2007NIAID Merit Award
    National Tainan Girls' Senior High School, Tainan, Taiwan2017Distinguished Alumni Award
    American Statistical Association2018Elected Fellow

    Collapse Overview 
    Collapse Overview
    Dr. Huang's research interest is in general biostatistics methodology and its application to the biomedical sciences. She has extensive experience in the statistical analysis of survival outcomes, recurrent events, competing risks, longitudinal measurements, missing data, and monitoring of clinical trials. In particular, she has developed novel nonparametric and semiparametric approaches for analyzing recurrent event data and panel count data under informative censoring, where a dependent terminal event, such as death, precludes further occurrence of recurrent events of interest. She also developed efficient estimation procedures to combine auxiliary subgroup survival or covariate effect information in the analysis of survival data, with the goal to improve risk prediction in cancer patients. Recently, she has developed efficient statistical methods for evaluating vaccine efficacy in clinical trials with active surveillance by incorporating information about the number of founder virus.

    Dr. Huang has published extensively in peer-reviewed journals in oncology and infectious diseases as a biostatistician. During her service at NIH (2004-2013), Dr. Huang worked closely with both extramural and intramural NIH scientists on the design, conduct, monitoring, analysis, and presentation of preclinical and clinical studies. As a former faculty member in the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (2013-2017), Dr. Huang was involved in the design and analysis of a range of clinical studies. She served as the principal statistician to the Breast and Ovarian Cancer Program and had collaborated on several pancreatic cancer studies.

    Collapse Research 
    Collapse Research Activities and Funding
    Comparing Patient Centered Outcomes in the Management of Pain between Emergency Departments and Dedicated Acute Care Facilities for Adults with Sickle Cell disease
    PCORI HIS-1403-11888Sep 1, 2017 - Dec 31, 2018
    Role: Principal Investigator (Subaward)
    Statistical Methods for Survival and Recurrent Event Data in Clinical Research
    NIH R01CA193888Jul 1, 2015 - Jun 30, 2020
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Sun Y, Qin J, Huang C. Missing information principle: a unified approach for general truncated and/or censored survival data problems. Statistical Science. 2018; 33:261-276.
    2. Chiou S, Huang C, Xu G, Yan J.Semiparametric regression analysis of panel count data: a practical review. International Statistical Review. 2018.
    3. Jose JJM, Brahmadathan KN, Abraham VJ, Huang C, Morens D, Hoe NP, Follmann DA, Krause RM. Streptococcal group A, C and G pharyngitis in school children: a prospective cohort study in Southern India. Epidemiol Infect. 2018 May; 146(7):848-853. PMID: 29616606.
      View in: PubMed
    4. Chiou SH, Xu G, Yan J, Huang C. Semiparametric estimation of the accelerated mean model with panel count data under informative examination times. Biometrics. 2017 Dec 29. PMID: 29286532.
      View in: PubMed
    5. Follmann D, Huang C. Sieve analysis using the number of infecting pathogens. Biometrics. 2017 Dec 14. PMID: 29238965.
      View in: PubMed
    6. Lee CH, Huang C, DeFor TE, Brunstein CG, Weisdorf DJ, Luo X.Semiparametric regression model for recurrent bacterial infections after umbilical cord blood transplantation. Statistica Sinica. 2017.
    7. Lyu T, Luo X, Xu G, Huang C. Induced smoothing for rank-based regression with recurrent gap time data. Stat Med. 2018 Mar 30; 37(7):1086-1100. PMID: 29205446.
      View in: PubMed
    8. Xu G, Sit T, Wang L, Huang C. Estimation and inference of quantile regression for survival data under biased sampling. J Am Stat Assoc. 2017; 520(112):1571-1586.
    9. Lee CH, Huang C, Xu G, Luo X. Semiparametric regression analysis for alternating recurrent event data. Stat Med. 2018 Mar 15; 37(6):996-1008. PMID: 29171035.
      View in: PubMed
    10. Murphy AG, Foley K, Rucki AA, Xia T, Jaffee EM, Huang C, Zheng L. Stromal Annexin A2 expression is predictive of decreased survival in pancreatic cancer. Oncotarget. 2017 Dec 05; 8(63):106405-106414. PMID: 29290958.
      View in: PubMed
    11. Shrestha B, Sun Y, Faisal F, Kim V, Soares K, Blair A, Herman JM, Narang A, Dholakia AS, Rosati L, Hacker-Prietz A, Chen L, Laheru DA, De Jesus-Acosta A, Le DT, Donehower R, Azad N, Diaz LA, Murphy A, Lee V, Fishman EK, Hruban RH, Liang T, Cameron JL, Makary M, Weiss MJ, Ahuja N, He J, Wolfgang CL, Huang C, Zheng L. Long-term survival benefit of upfront chemotherapy in patients with newly diagnosed borderline resectable pancreatic cancer. Cancer Med. 2017 Jul; 6(7):1552-1562. PMID: 28639410.
      View in: PubMed
    12. Sengupta S, Nagalingam A, Muniraj N, Bonner MY, Mistriotis P, Afthinos A, Kuppusamy P, Lanoue D, Cho S, Korangath P, Shriver M, Begum A, Merino VF, Huang C, Arbiser JL, Matsui W, Gyorffy B, Konstantopoulos K, Sukumar S, Marignani PA, Saxena NK, Sharma D. Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3. Oncogene. 2017 Oct 12; 36(41):5709-5721. PMID: 28581518.
      View in: PubMed
    13. Xu G, Chiou SH, Huang C, Wang MC, Yan J. Joint scale-change models for recurrent events and failure time. J Am Stat Assoc. 2017; 112(518):794-805. PMID: 28943684.
      View in: PubMed
    14. Sun Y, Huang C, Wang MC. Nonparametric Benefit-Risk Assessment Using Marker Process in the Presence of a Terminal Event. J Am Stat Assoc. 2017; 112(518):826-836. PMID: 29731529.
      View in: PubMed
    15. Huang C, Qin J, Tsai HT. Efficient Estimation of the Cox Model With Auxiliary Subgroup Survival Information. J Am Stat Assoc. 2016; 111(514):787-799. PMID: 27990035.
      View in: PubMed
    16. Follmann D, Huang C, Gabriel E. Who really gets strep sore throat? Confounding and effect modification of a time-varying exposure on recurrent events. Stat Med. 2016 10 30; 35(24):4398-4412. PMID: 27313096.
      View in: PubMed
    17. Huang C, Wang C, Wang MC. Nonparametric analysis of bivariate gap time with competing risks. Biometrics. 2016 09; 72(3):780-90. PMID: 26990686.
      View in: PubMed
    18. Li S, Sun Y, Huang C, Follmann DA, Krause R. Recurrent event data analysis with intermittently observed time-varying covariates. Stat Med. 2016 08 15; 35(18):3049-65. PMID: 26887664.
      View in: PubMed
    19. Avnir Y, Watson CT, Glanville J, Peterson EC, Tallarico AS, Bennett AS, Qin K, Fu Y, Huang C, Beigel JH, Breden F, Zhu Q, Marasco WA. IGHV1-69 polymorphism modulates anti-influenza antibody repertoires, correlates with IGHV utilization shifts and varies by ethnicity. Sci Rep. 2016 Feb 16; 6:20842. PMID: 26880249; PMCID: PMC4754645.
    20. Lee CH, Luo X, Huang C, DeFor TE, Brunstein CG, Weisdorf DJ. Nonparametric methods for analyzing recurrent gap time data with application to infections after hematopoietic cell transplant. Biometrics. 2016 06; 72(2):535-45. PMID: 26575402.
      View in: PubMed
    21. Skinner J, Huang C, Waisberg M, Felgner PL, Doumbo OK, Ongoiba A, Kayentao K, Traore B, Crompton PD, Williamson KC. Plasmodium falciparum Gametocyte-Specific Antibody Profiling Reveals Boosting through Natural Infection and Identifies Potential Markers of Gametocyte Exposure. Infect Immun. 2015 Nov; 83(11):4229-36. PMID: 26283330; PMCID: PMC4598406.
    22. Banga S, Coursen JD, Portugal S, Tran TM, Hancox L, Ongoiba A, Traore B, Doumbo OK, Huang C, Harty JT, Crompton PD. Impact of acute malaria on pre-existing antibodies to viral and vaccine antigens in mice and humans. PLoS One. 2015; 10(4):e0125090. PMID: 25919588; PMCID: PMC4412709.
    23. Huang C, Ning J, Qin J. Semiparametric likelihood inference for left-truncated and right-censored data. Biostatistics. 2015 Oct; 16(4):785-98. PMID: 25796430; PMCID: PMC4570578 [Available on 10/01/16].
    24. Follmann D, Huang C. Incorporating founder virus information in vaccine field trials. Biometrics. 2015 Jun; 71(2):386-96. PMID: 25773491; PMCID: PMC4729213.
    25. Sibley CT, Estwick T, Zavodni A, Huang C, Kwan AC, Soule BP, Long Priel DA, Remaley AT, Rudman Spergel AK, Turkbey EB, Kuhns DB, Holland SM, Malech HL, Zarember KA, Bluemke DA, Gallin JI. Assessment of atherosclerosis in chronic granulomatous disease. Circulation. 2014 Dec 02; 130(23):2031-9. PMID: 25239440.
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    26. Doumbo S, Tran TM, Sangala J, Li S, Doumtabe D, Kone Y, Traoré A, Bathily A, Sogoba N, Coulibaly ME, Huang C, Ongoiba A, Kayentao K, Diallo M, Dramane Z, Nutman TB, Crompton PD, Doumbo O, Traore B. Co-infection of long-term carriers of Plasmodium falciparum with Schistosoma haematobium enhances protection from febrile malaria: a prospective cohort study in Mali. PLoS Negl Trop Dis. 2014 Sep; 8(9):e3154. PMID: 25210876; PMCID: PMC4161351.
    27. Wang MC, Huang C. Statistical inference methods for recurrent event processes with shape and size parameters. Biometrika. 2014 Sep 01; 101(3):553-566. PMID: 26412863.
      View in: PubMed
    28. Gonçalves BP, Huang C, Morrison R, Holte S, Kabyemela E, Prevots DR, Fried M, Duffy PE. Parasite burden and severity of malaria in Tanzanian children. N Engl J Med. 2014 May 08; 370(19):1799-808. PMID: 24806160.
      View in: PubMed
    29. Avnir Y, Tallarico AS, Zhu Q, Bennett AS, Connelly G, Sheehan J, Sui J, Fahmy A, Huang C, Cadwell G, Bankston LA, McGuire AT, Stamatatos L, Wagner G, Liddington RC, Marasco WA. Molecular signatures of hemagglutinin stem-directed heterosubtypic human neutralizing antibodies against influenza A viruses. PLoS Pathog. 2014 May; 10(5):e1004103. PMID: 24788925; PMCID: PMC4006906.
    30. Cheng YJ, Huang C. Combined estimating equation approaches for semiparametric transformation models with length-biased survival data. Biometrics. 2014 Sep; 70(3):608-18. PMID: 24750126.
      View in: PubMed
    31. Marciano BE, Huang C, Joshi G, Rezaei N, Carvalho BC, Allwood Z, Ikinciogullari A, Reda SM, Gennery A, Thon V, Espinosa-Rosales F, Al-Herz W, Porras O, Shcherbina A, Szaflarska A, Kiliç S, Franco JL, Gómez Raccio AC, Roxo P, Esteves I, Galal N, Grumach AS, Al-Tamemi S, Yildiran A, Orellana JC, Yamada M, Morio T, Liberatore D, Ohtsuka Y, Lau YL, Nishikomori R, Torres-Lozano C, Mazzucchelli JT, Vilela MM, Tavares FS, Cunha L, Pinto JA, Espinosa-Padilla SE, Hernandez-Nieto L, Elfeky RA, Ariga T, Toshio H, Dogu F, Cipe F, Formankova R, Nuñez-Nuñez ME, Bezrodnik L, Marques JG, Pereira MI, Listello V, Slatter MA, Nademi Z, Kowalczyk D, Fleisher TA, Davies G, Neven B, Rosenzweig SD. BCG vaccination in patients with severe combined immunodeficiency: complications, risks, and vaccination policies. J Allergy Clin Immunol. 2014 Apr; 133(4):1134-41. PMID: 24679470.
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    32. Tsai HT, Isaacs C, Fu AZ, Warren JL, Freedman AN, Barac A, Huang C, Potosky AL. Risk of cardiovascular adverse events from trastuzumab (Herceptin(®)) in elderly persons with breast cancer: a population-based study. Breast Cancer Res Treat. 2014 Feb; 144(1):163-70. PMID: 24469642; PMCID: PMC4133778.
    33. Tran TM, Ongoiba A, Coursen J, Crosnier C, Diouf A, Huang C, Li S, Doumbo S, Doumtabe D, Kone Y, Bathily A, Dia S, Niangaly M, Dara C, Sangala J, Miller LH, Doumbo OK, Kayentao K, Long CA, Miura K, Wright GJ, Traore B, Crompton PD. Naturally acquired antibodies specific for Plasmodium falciparum reticulocyte-binding protein homologue 5 inhibit parasite growth and predict protection from malaria. J Infect Dis. 2014 Mar 01; 209(5):789-98. PMID: 24133188; PMCID: PMC3923542.
    34. Matharu K, Zarember KA, Marciano BE, Kuhns DB, Spalding C, Garofalo M, Dimaggio T, Estwick T, Huang C, Fink D, Priel DL, Fleisher TA, Holland SM, Malech HL, Gallin JI. B-cell activating factor (BAFF) is elevated in chronic granulomatous disease. Clin Immunol. 2013 Aug; 148(2):258-64. PMID: 23773925.
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    35. Waisberg M, Lin CK, Huang C, Pena M, Orandle M, Bolland S, Pierce SK. The impact of genetic susceptibility to systemic lupus erythematosus on placental malaria in mice. PLoS One. 2013; 8(5):e62820. PMID: 23675429; PMCID: PMC3651086.
    36. Tran TM, Li S, Doumbo S, Doumtabe D, Huang C, Dia S, Bathily A, Sangala J, Kone Y, Traore A, Niangaly M, Dara C, Kayentao K, Ongoiba A, Doumbo OK, Traore B, Crompton PD. An intensive longitudinal cohort study of Malian children and adults reveals no evidence of acquired immunity to Plasmodium falciparum infection. Clin Infect Dis. 2013 Jul; 57(1):40-7. PMID: 23487390; PMCID: PMC3669526.
    37. Luo X, Huang C, Wang L. Quantile regression for recurrent gap time data. Biometrics. 2013 Jun; 69(2):375-85. PMID: 23489055.
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    38. Galindo-Fraga A, Ortiz-Hernández AA, Ramírez-Venegas A, Vázquez RV, Moreno-Espinosa S, Llamosas-Gallardo B, Pérez-Patrigeon S, Salinger M, Freimanis L, Huang C, Gu W, Guerrero ML, Beigel J, Ruiz-Palacios GM. Clinical characteristics and outcomes of influenza and other influenza-like illnesses in Mexico City. Int J Infect Dis. 2013 Jul; 17(7):e510-7. PMID: 23416208.
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    39. Huang C, Qin J. Semiparametric estimation for the additive hazards model with left-truncated and right-censored data. Biometrika. 2013; 100(4):877-888. PMID: 26246622.
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    40. Huang C, Qin J. Composite Partial Likelihood Estimation Under Length-Biased Sampling, With Application to a Prevalent Cohort Study of Dementia. J Am Stat Assoc. 2012 Sep 01; 107(499):946-857. PMID: 24000265.
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    41. Huang C, Qin J, Follmann DA. A maximum pseudo-profile likelihood estimator for the Cox model under length-biased sampling. Biometrika. 2012 Mar; 99(1):199-210. PMID: 23843659.
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    42. De Pascalis R, Chou AY, Bosio CM, Huang C, Follmann DA, Elkins KL. Development of functional and molecular correlates of vaccine-induced protection for a model intracellular pathogen, F. tularensis LVS. PLoS Pathog. 2012 Jan; 8(1):e1002494. PMID: 22275868; PMCID: PMC3262015.
    43. Srinivasula S, Lempicki RA, Adelsberger JW, Huang C, Roark J, Lee PI, Rupert A, Stevens R, Sereti I, Lane HC, Di Mascio M, Kovacs JA. Differential effects of HIV viral load and CD4 count on proliferation of naive and memory CD4 and CD8 T lymphocytes. Blood. 2011 Jul 14; 118(2):262-70. PMID: 21562041; PMCID: PMC3138680.
    44. Sui J, Sheehan J, Hwang WC, Bankston LA, Burchett SK, Huang C, Liddington RC, Beigel JH, Marasco WA. Wide prevalence of heterosubtypic broadly neutralizing human anti-influenza A antibodies. Clin Infect Dis. 2011 Apr 15; 52(8):1003-9. PMID: 21460314; PMCID: PMC3070035.
    45. Huang C, Qin J. Nonparametric estimation for length-biased and right-censored data. Biometrika. 2011 Mar; 98(1):177-186. PMID: 23049126.
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    46. Luo X, Huang C. Analysis of recurrent gap time data using the weighted risk-set method and the modified within-cluster resampling method. Stat Med. 2011 Feb 20; 30(4):301-11. PMID: 20963733.
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    47. Waisberg M, Tarasenko T, Vickers BK, Scott BL, Willcocks LC, Molina-Cruz A, Pierce MA, Huang C, Torres-Velez FJ, Smith KG, Barillas-Mury C, Miller LH, Pierce SK, Bolland S. Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in mice. Proc Natl Acad Sci U S A. 2011 Jan 18; 108(3):1122-7. PMID: 21187399; PMCID: PMC3024697.
    48. Huang C, Luo X, Follmann DA. A model checking method for the proportional hazards model with recurrent gap time data. Biostatistics. 2011 Jul; 12(3):535-47. PMID: 21138876; PMCID: PMC3138070.
    49. Tavel JA, Huang C, Shen J, Metcalf JA, Dewar R, Shah A, Vasudevachari MB, Follmann DA, Herpin B, Davey RT, Polis MA, Kovacs J, Masur H, Lane HC. Interferon-alpha produces significant decreases in HIV load. J Interferon Cytokine Res. 2010 Jul; 30(7):461-4. PMID: 20235638; PMCID: PMC2964361.
    50. Weiss GE, Traore B, Kayentao K, Ongoiba A, Doumbo S, Doumtabe D, Kone Y, Dia S, Guindo A, Traore A, Huang C, Miura K, Mircetic M, Li S, Baughman A, Narum DL, Miller LH, Doumbo OK, Pierce SK, Crompton PD. The Plasmodium falciparum-specific human memory B cell compartment expands gradually with repeated malaria infections. PLoS Pathog. 2010 May 20; 6(5):e1000912. PMID: 20502681; PMCID: PMC2873912.
    51. Huang C, Qin J, Wang MC.Semiparametric analysis for recurrent event data with time-dependent covariates and informative censoring . Biometrics. 2010; 66(1):39-49.
    52. Crompton PD, Miura K, Traore B, Kayentao K, Ongoiba A, Weiss G, Doumbo S, Doumtabe D, Kone Y, Huang C, Doumbo OK, Miller LH, Long CA, Pierce SK. In vitro growth-inhibitory activity and malaria risk in a cohort study in mali. Infect Immun. 2010 Feb; 78(2):737-45. PMID: 19917712; PMCID: PMC2812204.
    53. Traore B, Koné Y, Doumbo S, Doumtabé D, Traoré A, Crompton PD, Mircetic M, Huang C, Kayentao K, Dicko A, Sagara I, Ellis RD, Miura K, Guindo A, Miller LH, Doumbo OK, Pierce SK. The TLR9 agonist CpG fails to enhance the acquisition of Plasmodium falciparum-specific memory B cells in semi-immune adults in Mali. Vaccine. 2009 Dec 09; 27(52):7299-303. PMID: 19712767.
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    54. Beigel JH, Voell J, Huang C, Burbelo PD, Lane HC. Safety and immunogenicity of multiple and higher doses of an inactivated influenza A/H5N1 vaccine. J Infect Dis. 2009 Aug 15; 200(4):501-9. PMID: 19569973.
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    55. Zarember KA, Cruz AR, Huang C, Gallin JI. Antifungal activities of natural and synthetic iron chelators alone and in combination with azole and polyene antibiotics against Aspergillus fumigatus. Antimicrob Agents Chemother. 2009 Jun; 53(6):2654-6. PMID: 19307370; PMCID: PMC2687209.
    56. Crompton PD, Mircetic M, Weiss G, Baughman A, Huang C, Topham DJ, Treanor JJ, Sanz I, Lee FE, Durbin AP, Miura K, Narum DL, Ellis RD, Malkin E, Mullen GE, Miller LH, Martin LB, Pierce SK. The TLR9 ligand CpG promotes the acquisition of Plasmodium falciparum-specific memory B cells in malaria-naive individuals. J Immunol. 2009 Mar 01; 182(5):3318-26. PMID: 19234231.
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    57. Engler RJ, Nelson MR, Klote MM, VanRaden MJ, Huang C, Cox NJ, Klimov A, Keitel WA, Nichol KL, Carr WW, Treanor JJ. Half- vs full-dose trivalent inactivated influenza vaccine (2004-2005): age, dose, and sex effects on immune responses. Arch Intern Med. 2008 Dec 08; 168(22):2405-14. PMID: 19064822.
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    58. Crompton PD, Traore B, Kayentao K, Doumbo S, Ongoiba A, Diakite SA, Krause MA, Doumtabe D, Kone Y, Weiss G, Huang C, Doumbia S, Guindo A, Fairhurst RM, Miller LH, Pierce SK, Doumbo OK. Sickle cell trait is associated with a delayed onset of malaria: implications for time-to-event analysis in clinical studies of malaria. J Infect Dis. 2008 Nov 01; 198(9):1265-75. PMID: 18752444.
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    59. Read SW, Lempicki RA, Di Mascio M, Srinivasula S, Burke R, Sachau W, Bosche M, Adelsberger JW, Sereti I, Davey RT, Tavel JA, Huang C, Issaq HJ, Fox SD, Lane H, Kovacs JA. CD4 T cell survival after intermittent interleukin-2 therapy is predictive of an increase in the CD4 T cell count of HIV-infected patients. J Infect Dis. 2008 Sep 15; 198(6):843-50. PMID: 18684102.
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    60. Huang C, Qin J, Follmann DA. Empirical Likelihood-Based Estimation of the Treatment Effect in a Pretest-Posttest Study. J Am Stat Assoc. 2008 Sep 01; 103(483):1270-1280. PMID: 23729942.
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    61. Chiung-Yu Huang, Xianghua Luo.The Statistical Analysis of Recurrent Events by COOK, R. J. and LAWLESS, J. F. Biometrics. 2008; 64(3):987-988.
    62. Luo X, Wang MC, Huang C. A comparison of various rate functions of a recurrent event process in the presence of a terminal event. Stat Methods Med Res. 2010 Apr; 19(2):167-82. PMID: 18445699.
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    63. Huang C, Qin J, Zou F.Empirical likelihood-based inference for genetic mixture models. Canadian Journal of Statistics. 2007; 35(4):563-574.
    64. Khaliq AA, Huang C, Ganti AK, Invie K, Smego RA. Comparison of resource utilization and clinical outcomes between teaching and nonteaching medical services. J Hosp Med. 2007 May; 2(3):150-7. PMID: 17549749.
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    65. Zonios DI, Falloon J, Huang C, Chaitt D, Bennett JE. Cryptococcosis and idiopathic CD4 lymphocytopenia. Medicine (Baltimore). 2007 Mar; 86(2):78-92. PMID: 17435588.
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    66. Fay MP, Huang C, Twum-Danso NA. Monitoring rare serious adverse events from a new treatment and testing for a difference from historical controls. Clin Trials. 2007; 4(6):598-610. PMID: 18042569.
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    67. Huang C, Wang MC, Zhang Y. Analysing panel count data with informative observation times. Biometrika. 2006 Dec; 93(4):763-775. PMID: 23729818.
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    68. Walter Bockting, Chiung-Yu Huang, Hua Ding, Beatrice “Bean” Robinson, BR Simon Rosser.Are transgender persons at higher risk for HIV than other sexual minorities? A comparison of HIV prevalence and risks. International Journal of Transgenderism. 2005; 8(2-3):123-131.
    69. Khaliq AA, Dimassi H, Huang C, Narine L, Smego RA. Disciplinary action against physicians: who is likely to get disciplined? Am J Med. 2005 Jul; 118(7):773-7. PMID: 15989912.
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    70. Huang C, Wang MC. Nonparametric estimation of the bivariate recurrence time distribution. Biometrics. 2005 Jun; 61(2):392-402. PMID: 16011685.
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    71. Chiang CT, Wang MC, Huang C. Kernel Estimation of Rate Function for Recurrent Event Data. Scand Stat Theory Appl. 2005 Mar; 32(1):77-91. PMID: 24062598.
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    72. Huang C, Wang MC. Joint Modeling and Estimation for Recurrent Event Processes and Failure Time Data. J Am Stat Assoc. 2004 Dec; 99(468):1153-1165. PMID: 24068850.
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    73. Hu TC, Huang C, Rosalsky A.On stability of trimmed sums. Probability and Mathematical Statistics. 2003; 23(1):153-172.
    74. Rosenblatt A, Brinkman RR, Liang KY, Almqvist EW, Margolis RL, Huang C, Sherr M, Franz ML, Abbott MH, Hayden MR, Ross CA. Familial influence on age of onset among siblings with Huntington disease. Am J Med Genet. 2001 Jul 08; 105(5):399-403. PMID: 11449389.
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    75. Liang KY, Huang C, Beaty TH. A unified sampling approach for multipoint analysis of qualitative and quantitative traits in sib pairs. Am J Hum Genet. 2000 May; 66(5):1631-41. PMID: 10762548; PMCID: PMC1378021.
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