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Distinct trajectories distinguish antigen-specific T cells in peanut-allergic individuals undergoing oral immunotherapy. J Allergy Clin Immunol. 2023 07; 152(1):155-166.e9.
Calise J, DeBerg H, Garabatos N, Khosa S, Bajzik V, Calderon LB, Aldridge K, Rosasco M, Ferslew BC, Zhu T, Smulders R, Wheatley LM, Laidlaw TM, Qin T, Chichili GR, Adelman DC, Farrington M, Robinson D, Jeong D, Jones SM, Sanda S, Larson D, Kwok WW, Baloh C, Nepom GT, Wambre E, IMPACT. PMID: 37003475; PMCID: PMC10330178.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Participant characteristics and safety outcomes of peanut oral immunotherapy in the RAMSES and ARC011 trials. Ann Allergy Asthma Immunol. 2022 12; 129(6):758-768.e4.
Ciaccio C, Goldsobel AB, Anagnostou A, Beyer K, Casale TB, Deschildre A, Fernández-Rivas M, Hourihane JO, Krawiec M, Lieberman J, Scurlock AM, Vickery BP, Smith A, Tilles SA, Adelman DC, Brown KR, RAMSES (ARC007) and ARC011 Study Groups:. PMID: 35973655.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCTClinical Trials
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Reply. J Allergy Clin Immunol. 2022 07; 150(1):230-232.
Baker J, Beyer K, du Toit G, Shreffler W, Brown KR, Norval D, Vereda A, Adelman D, Jones SM, Burks W, Casale T. PMID: 35491264.
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PubMed Mentions: Fields:
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Updating the CoFAR Grading Scale for Systemic Allergic Reactions in Food Allergy. J Allergy Clin Immunol. 2022 06; 149(6):2166-2170.e1.
Chinthrajah RS, Jones SM, Kim EH, Sicherer SH, Shreffler W, Lanser BJ, Atri N, Babineau DC, Adelman DC, Iqbal A, Limb SL, Rudman Spergel AK, Togias A, Wood RA. PMID: 35026206; PMCID: PMC9177543.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Safety of peanut (Arachis hypogaea) allergen powder-dnfp in children and teenagers with peanut allergy: Pooled summary of phase 3 and extension trials. J Allergy Clin Immunol. 2022 06; 149(6):2043-2052.e9.
Brown KR, Baker J, Vereda A, Beyer K, Burks AW, du Toit G, O'B Hourihane J, Jones SM, Norval D, Dana A, Shreffler W, Vickery BP, Casale T, Skeel B, Adelman D. PMID: 34971646.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCTClinical Trials
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Onset of eosinophilic esophagitis during a clinical trial program of oral immunotherapy for peanut allergy. J Allergy Clin Immunol Pract. 2021 12; 9(12):4496-4501.
Nilsson C, Scurlock AM, Dellon ES, Brostoff JM, Pham T, Ryan R, Brown KR, Adelman DC, Aceves SS. PMID: 34389504.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Using data from food challenges to inform management of consumers with food allergy: A systematic review with individual participant data meta-analysis. J Allergy Clin Immunol. 2021 06; 147(6):2249-2262.e7.
Patel N, Adelman DC, Anagnostou K, Baumert JL, Blom WM, Campbell DE, Chinthrajah RS, Mills ENC, Javed B, Purington N, Remington BC, Sampson HA, Smith AD, Yarham RAR, Turner PJ. PMID: 33571537; PMCID: PMC8168954.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
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Continuous and Daily Oral Immunotherapy for Peanut Allergy: Results from a 2-Year Open-Label Follow-On Study. J Allergy Clin Immunol Pract. 2021 05; 9(5):1879-1889.e13.
Vickery BP, Vereda A, Nilsson C, du Toit G, Shreffler WG, Burks AW, Jones SM, Fernández-Rivas M, Blümchen K, O'B Hourihane J, Beyer K, Anagnostou A, Assa'ad AH, Ben-Shoshan M, Bird JA, Carr TF, Carr WW, Casale TB, Chong HJ, Ciaccio CE, Dorsey MJ, Fineman SM, Fritz SB, Greiner AN, Greos LS, Hampel FC, Ibáñez MD, Jeong DK, Johnston DT, Kachru R, Kim EH, Lanser BJ, Leonard SA, Maier MC, Mansfield LE, Muraro A, Ohayon JA, Oude Elberink JNG, Petroni DH, Pongracic JA, Portnoy JM, Rachid R, Rupp NT, Sanders GM, Sharma HP, Sharma V, Sher ER, Sher L, Sindher SB, Siri D, Spergel JM, Sprikkelman AB, Sussman GL, Tsoumani M, Varshney P, Vitalpur G, Wang J, Yang WH, Zubeldia JM, Smith A, Ryan R, Adelman DC. PMID: 33359589.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimals
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Efficacy and safety of oral immunotherapy with AR101 in European children with a peanut allergy (ARTEMIS): a multicentre, double-blind, randomised, placebo-controlled phase 3 trial. Lancet Child Adolesc Health. 2020 10; 4(10):728-739.
O'B Hourihane J, Beyer K, Abbas A, Fernández-Rivas M, Turner PJ, Blumchen K, Nilsson C, Ibáñez MD, Deschildre A, Muraro A, Sharma V, Erlewyn-Lajeunesse M, Zubeldia JM, De Blay F, Sauvage CD, Byrne A, Chapman J, Boralevi F, DunnGalvin A, O'Neill C, Norval D, Vereda A, Skeel B, Adelman DC, du Toit G. PMID: 32702315.
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PubMed Mentions:
44 Fields:
Translation:
HumansCTClinical Trials
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Latiglutenase Treatment for Celiac Disease: Symptom and Quality of Life Improvement for Seropositive Patients on a Gluten-Free Diet. GastroHep. 2019 Nov; 1(6):293-301.
Syage JA, Green PHR, Khosla C, Adelman DC, Sealey-Voyksner JA, Murray JA. PMID: 32313451; PMCID: PMC7169937.
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PubMed Mentions:
14
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AR101 Oral Immunotherapy for Peanut Allergy. N Engl J Med. 2018 Nov 22; 379(21):1991-2001.
PALISADE Group of Clinical Investigators, Vickery BP, Vereda A, Casale TB, Beyer K, du Toit G, Hourihane JO, Jones SM, Shreffler WG, Marcantonio A, Zawadzki R, Sher L, Carr WW, Fineman S, Greos L, Rachid R, Ibáñez MD, Tilles S, Assa’ad AH, Nilsson C, Rupp N, Welch MJ, Sussman G, Chinthrajah S, Blumchen K, Sher E, Spergel JM, Leickly FE, Zielen S, Wang J, Sanders GM, Wood RA, Cheema A, Bindslev-Jensen C, Leonard S, Kachru R, Johnston DT, Hampel FC, Kim EH, Anagnostou A, Pongracic JA, Ben-Shoshan M, Sharma HP, Stillerman A, Windom HH, Yang WH, Muraro A, Zubeldia JM, Sharma V, Dorsey MJ, Chong HJ, Ohayon J, Bird JA, Carr TF, Siri D, Fernández-Rivas M, Jeong DK, Fleischer DM, Lieberman JA, Dubois AEJ, Tsoumani M, Ciaccio CE, Portnoy JM, Mansfield LE, Fritz SB, Lanser BJ, Matz J, Oude Elberink HNG, Varshney P, Dilly SG, Adelman DC, Burks AW. PMID: 30449234.
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PubMed Mentions:
194 Fields:
Translation:
HumansAnimalsCTClinical Trials
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Measuring Change In Small Intestinal Histology In Patients With Celiac Disease. Am J Gastroenterol. 2018 03; 113(3):339-347.
Adelman DC, Murray J, Wu TT, Mäki M, Green PH, Kelly CP. PMID: 29460921.
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PubMed Mentions:
37 Fields:
Translation:
HumansCells
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Factors associated with villus atrophy in symptomatic coeliac disease patients on a gluten-free diet. Aliment Pharmacol Ther. 2017 04; 45(8):1084-1093.
Mahadev S, Murray JA, Wu TT, Chandan VS, Torbenson MS, Kelly CP, Maki M, Green PH, Adelman D, Lebwohl B. PMID: 28220520.
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PubMed Mentions:
28 Fields:
Translation:
Humans
-
A Novel Patient-Derived Conceptual Model of the Impact of Celiac Disease in Adults: Implications for Patient-Reported Outcome and Health-Related Quality-of-Life Instrument Development. Value Health. 2017 04; 20(4):637-643.
Leffler DA, Acaster S, Gallop K, Dennis M, Kelly CP, Adelman DC. PMID: 28408006.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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A B-Cell Gene Signature Correlates With the Extent of Gluten-Induced Intestinal Injury in Celiac Disease. Cell Mol Gastroenterol Hepatol. 2017 Jul; 4(1):1-17.
Garber ME, Saldanha A, Parker JS, Jones WD, Kaukinen K, Laurila K, Lähdeaho ML, Khatri P, Khosla C, Adelman DC, Mäki M. PMID: 28508029; PMCID: PMC5413199.
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PubMed Mentions:
7 Fields:
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No Difference Between Latiglutenase and Placebo in Reducing Villous Atrophy or Improving Symptoms in Patients With Symptomatic Celiac Disease. Gastroenterology. 2017 03; 152(4):787-798.e2.
Murray JA, Kelly CP, Green PHR, Marcantonio A, Wu TT, Mäki M, Adelman DC, CeliAction Study Group of Investigators. PMID: 27864127.
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PubMed Mentions:
44 Fields:
Translation:
HumansCTClinical Trials
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Assessing Quality of Life in Patients with Common Variable Immunodeficiency: Why It Matters. J Allergy Clin Immunol Pract. 2016 Nov - Dec; 4(6):1180-1181.
Adelman DC, Howard K. PMID: 27836063.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
Glutenase ALV003 attenuates gluten-induced mucosal injury in patients with celiac disease. Gastroenterology. 2014 Jun; 146(7):1649-58.
Lähdeaho ML, Kaukinen K, Laurila K, Vuotikka P, Koivurova OP, Kärjä-Lahdensuu T, Marcantonio A, Adelman DC, Mäki M. PMID: 24583059.
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PubMed Mentions:
81 Fields:
Translation:
HumansCells
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Allergen skin tests and free IgE levels during reduction and cessation of omalizumab therapy. J Allergy Clin Immunol. 2008 Feb; 121(2):506-11.
Corren J, Shapiro G, Reimann J, Deniz Y, Wong D, Adelman D, Togias A. PMID: 18269927.
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PubMed Mentions:
24 Fields:
Translation:
Humans
-
A phase 1 study of SNS-032 (formerly BMS-387032), a potent inhibitor of cyclin-dependent kinases 2, 7 and 9 administered as a single oral dose and weekly infusion in patients with metastatic refractory solid tumors. Invest New Drugs. 2008 Feb; 26(1):59-65.
Heath EI, Bible K, Martell RE, Adelman DC, Lorusso PM. PMID: 17938863.
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PubMed Mentions:
38 Fields:
Translation:
HumansCTClinical Trials
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Effects of omalizumab, a humanized monoclonal anti-IgE antibody, on nasal reactivity to allergen and local IgE synthesis. Ann Allergy Asthma Immunol. 2004 Sep; 93(3):243-8.
Corren J, Diaz-Sanchez D, Saxon A, Deniz Y, Reimann J, Sinclair D, Davancaze T, Adelman D. PMID: 15478383.
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Phase I drug and light dose-escalation trial of motexafin lutetium and far red light activation (phototherapy) in subjects with coronary artery disease undergoing percutaneous coronary intervention and stent deployment: procedural and long-term results. Circulation. 2003 Sep 16; 108(11):1310-5.
Kereiakes DJ, Szyniszewski AM, Wahr D, Herrmann HC, Simon DI, Rogers C, Kramer P, Shear W, Yeung AC, Shunk KA, Chou TM, Popma J, Fitzgerald P, Carroll TE, Forer D, Adelman DC. PMID: 12939212.
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PubMed Mentions:
22 Fields:
Translation:
HumansCTClinical Trials
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Photodynamic therapy: applications in atherosclerotic vascular disease with motexafin lutetium. Catheter Cardiovasc Interv. 2002 Nov; 57(3):387-94.
Chou TM, Woodburn KW, Cheong WF, Lacy SA, Sudhir K, Adelman DC, Wahr D. PMID: 12410519.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Pharmacological approaches. Clin Allergy Immunol. 2002; 16:469-94.
Avila PC, Kishiyama JL, Adelman DC. PMID: 11577555.
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PubMed Mentions: Fields:
Translation:
Humans
-
Photodynamic therapy with motexafin lutetium induces redox-sensitive apoptosis of vascular cells. Arterioscler Thromb Vasc Biol. 2001 May; 21(5):759-64.
Chen Z, Woodburn KW, Shi C, Adelman DC, Rogers C, Simon DI. PMID: 11348871.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Photoangioplasty for human peripheral atherosclerosis: results of a phase I trial of photodynamic therapy with motexafin lutetium (Antrin). Circulation. 2000 Nov 07; 102(19):2322-4.
Rockson SG, Kramer P, Razavi M, Szuba A, Filardo S, Fitzgerald P, Cooke JP, Yousuf S, DeVault AR, Renschler MF, Adelman DC. PMID: 11067782.
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PubMed Mentions:
21 Fields:
Translation:
HumansCTClinical Trials
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Letter to the editor regarding the use of intravenous immunoglobulin (IVIG) in asthma. Clin Immunol. 1999 Nov; 93(2):184-6.
Shearer WT, Abramson SL, Adelman DC, Corn B, Cunningham-Rundles C, Kishiyama JL, Richmond W, Shames RS, Sperber K, Stiehm ER, Valacer DJ. PMID: 10527695.
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PubMed Mentions: Fields:
Translation:
Humans
-
Effect of aerosolized anti-IgE (E25) on airway responses to inhaled allergen in asthmatic subjects. Am J Respir Crit Care Med. 1999 Sep; 160(3):1023-7.
Fahy JV, Cockcroft DW, Boulet LP, Wong HH, Deschesnes F, Davis EE, Ruppel J, Su JQ, Adelman DC. PMID: 10471635.
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PubMed Mentions:
27 Fields:
Translation:
HumansCTClinical Trials
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A multicenter, randomized, double-blind, placebo-controlled trial of high-dose intravenous immunoglobulin for oral corticosteroid-dependent asthma. Clin Immunol. 1999 May; 91(2):126-33.
Kishiyama JL, Valacer D, Cunningham-Rundles C, Sperber K, Richmond GW, Abramson S, Glovsky M, Stiehm R, Stocks J, Rosenberg L, Shames RS, Corn B, Shearer WT, Bacot B, DiMaio M, Tonetta S, Adelman DC. PMID: 10227804.
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PubMed Mentions:
10 Fields:
Translation:
HumansCTClinical Trials
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Clinical differences among women with and without self-reported perimenstrual asthma. Ann Allergy Asthma Immunol. 1998 Jul; 81(1):65-72.
Shames RS, Heilbron DC, Janson SL, Kishiyama JL, Au DS, Adelman DC. PMID: 9690575.
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PubMed Mentions:
30 Fields:
Translation:
Humans
-
Use of an anti-IgE humanized monoclonal antibody in ragweed-induced allergic rhinitis. J Allergy Clin Immunol. 1997 Jul; 100(1):110-21.
Casale TB, Bernstein IL, Busse WW, LaForce CF, Tinkelman DG, Stoltz RR, Dockhorn RJ, Reimann J, Su JQ, Fick RB, Adelman DC. PMID: 9257795.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCTClinical Trials
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Down-regulation of Fc(epsilon)RI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody. J Immunol. 1997 Feb 01; 158(3):1438-45.
MacGlashan DW, Bochner BS, Adelman DC, Jardieu PM, Togias A, McKenzie-White J, Sterbinsky SA, Hamilton RG, Lichtenstein LM. PMID: 9013989.
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PubMed Mentions:
199 Fields:
Translation:
HumansCellsCTClinical Trials
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CD45 isoforms on human CD4+ T-cell subsets. J Allergy Clin Immunol. 1996 Aug; 98(2):433-40.
Shanafelt MC, Yssel H, Soderberg C, Steinman L, Adelman DC, Peltz G, Lahesmaa R. PMID: 8757221.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Genetic basis of the primary immunodeficiency syndromes. West J Med. 1995 Oct; 163(4):373-4.
Adelman DC. PMID: 7483602; PMCID: PMC1303141.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Core content outline for clinical and laboratory immunology. AAAI Training Program Directors' Committee. J Allergy Clin Immunol. 1994 Dec; 94(6 Pt 1):933-41.
Shearer WT, Adelman DC, Huston DP, Engler RJ, Gupta S, Ledford DK, Lopez M, Du Buske LM. PMID: 7798541.
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PubMed Mentions: Fields:
Translation:
Humans
-
The cross-reactivity and immunology of beta-lactam antibiotics. Drug Saf. 1994 Apr; 10(4):318-27.
Kishiyama JL, Adelman DC. PMID: 8018304.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Isotype-specific regulation of human lymphocyte production of immunoglobulins by sustained exposure to vasoactive intestinal peptide. J Allergy Clin Immunol. 1993 Dec; 92(6):891-901.
Hassner A, Lau MS, Goetzl EJ, Adelman DC. PMID: 8258623.
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PubMed Mentions: Fields:
Translation:
HumansCells
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13-cis retinoic acid enhances in vivo B-lymphocyte differentiation in patients with common variable immunodeficiency. J Allergy Clin Immunol. 1991 Nov; 88(5):705-12.
Adelman DC, Yen TY, Cumberland WG, Sidell N, Saxon A. PMID: 1720149.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCellsCTClinical Trials
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Biologic response modifiers in primary immunodeficiency disorders. Ann Intern Med. 1991 Aug 15; 115(4):294-307.
Hassner A, Adelman DC. PMID: 1854114.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Penicillin allergy. West J Med. 1991 Apr; 154(4):456.
Adelman D. PMID: 1877185; PMCID: PMC1002794.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
Molecular characteristics of the cellular receptor for vasoactive intestinal peptide. Trans Assoc Am Physicians. 1991; 104:54-61.
Goetzl EJ, Hassner A, Cheng PP, Robichon A, Adelman DC, Sreedharan SP. PMID: 1668991.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Neuropeptides, mast cells and allergy: novel mechanisms and therapeutic possibilities. Clin Exp Allergy. 1990 Nov; 20 Suppl 4:3-7.
Goetzl EJ, Cheng PP, Hassner A, Adelman DC, Frick OL, Sreedharan SP. PMID: 2282540.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Elevated serum interleukin-6 associated with a failure in B cell differentiation in common variable immunodeficiency. J Allergy Clin Immunol. 1990 Oct; 86(4 Pt 1):512-21.
Adelman DC, Matsuda T, Hirano T, Kishimoto T, Saxon A. PMID: 2229813.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Neuroimmunology. Adv Immunol. 1990; 48:161-90.
Goetzl EJ, Adelman DC, Sreedharan SP. PMID: 1971989.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Acute respiratory emergencies in emergency treatment of the injured athlete. Clin Sports Med. 1989 Jan; 8(1):71-9.
Adelman DC, Spector SL. PMID: 2663179.
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PubMed Mentions: Fields:
Translation:
HumansPHPublic Health
-
Fixed cutaneous eruptions to seminal-plasma challenge: a case report. Fertil Steril. 1988 Sep; 50(3):532-4.
Best CL, Walters C, Adelman DC. PMID: 3410107.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Imipenem cross-reactivity with penicillin in humans. J Allergy Clin Immunol. 1988 Aug; 82(2):213-7.
Saxon A, Adelman DC, Patel A, Hajdu R, Calandra GB. PMID: 2457043.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCTClinical Trials
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Retinoic acid induces the differentiation of B cell hybridomas from patients with common variable immunodeficiency. J Exp Med. 1988 Jul 01; 168(1):55-71.
Sherr E, Adelman DC, Saxon A, Gilly M, Wall R, Sidell N. PMID: 3294336; PMCID: PMC2189392.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Recurrent bacterial infections and cellulitis in a 29-year-old woman with a history of hypogammaglobulinemia. Ann Allergy. 1987 Dec; 59(6):403-4, 456-8.
Adelman DC, Saxon A. PMID: 3425979.
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PubMed Mentions: Fields:
Translation:
Humans
-
Immediate hypersensitivity reactions to beta-lactam antibiotics. Ann Intern Med. 1987 Aug; 107(2):204-15.
Saxon A, Beall GN, Rohr AS, Adelman DC. PMID: 3300459.
View in:
PubMed Mentions:
45 Fields:
Translation:
Humans