My research focuses on the immunology and genetics of diabetes. I run a research lab that utilizes cell line experiments, analysis of human samples, large data set analysis, and clinical research to develop biomarkers and new paradigms of human disease. My current projects focus on type 1 diabetes and cystic fibrosis related diabetes (CFRD).
In addition, I am an Associate Director of Clinical and Translational Medicine in the Immune Tolerance Network, a large NIH sponsored clinical trials consortium that designs novel immune modulating trials in type 1 diabetes, allergy, transplantation, and autoimmune diseases (https://www.immunetolerance.org) . I design international, multi-center clinical trials in type 1 diabetes and allergic disease utilizing cutting-edge immune modulation therapy. In this role I am responsible for study design, protocol writing, site management, medical monitoring, data analysis, and manuscript preparation. I also contribute to the regulatory filing process including participating in pre-IND and IND meetings with federal regulators. This work informs, and is informed by, the work at the bench.