Srinath Sanda, MD

Title(s)Professor, Pediatrics
SchoolSchool of Medicine
Address513 Parnassus Avenue, MSB, #001
San Francisco CA 94143
Phone415-514-5234
PronounsHe/Him/His
ORCID ORCID Icon0000-0002-6983-6864 Additional info
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    Collapse Biography 
    Collapse Education and Training
    UC Davis, Davis, CAM.D.06/1997Medicine
    Cedars-Sinai Medical Center, Los Angeles, CA06/2001Internal Medicine/Pediatrics
    Cedar-Sinai Medical Center, Los Angeles, CA06/2002Pediatrics Chief Resident
    UC San Diego, La Jolla, CA06/2007Pediatric Endocrinology

    Collapse Overview 
    Collapse Overview
    My research focuses on the immunology and genetics of diabetes. I run a research lab that utilizes cell line experiments, analysis of human samples, large data set analysis, and clinical research to develop biomarkers and new paradigms of human disease. My current projects focus on type 1 diabetes and cystic fibrosis related diabetes (CFRD).

    In addition, I am a Director of Clinical and Translational Medicine in the Immune Tolerance Network, a large NIH-sponsored clinical trials consortium that conductsl immune modulating trials in type 1 diabetes, allergy, transplantation, and autoimmune diseases (https://www.immunetolerance.org). I design international, multi-center phase 1 and 2 clinical trials in type 1 diabetes and allergic disease utilizing cutting-edge immune modulation therapy. We combine data from the clinical trials data with cutting edge immunophenotyping data to better understand mechanisms of immune tolerance in humans.
    Collapse Interests

    Collapse Research 
    Collapse Research Activities and Funding
    Islet autoimmunity in patients with STAT gain-of-function mutations
    Helmsley Charitable Trust Dec 1, 2021 - Nov 30, 2022
    Role: Principal Investigator
    Description: Our goal is to quantify and characterize immunologic and genetic markers of islet autoimmunity in patients with STAT gain-of-function mutations.

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Enhanced Gut Microbiome Capacity for Amino Acid Metabolism is associated with Peanut Oral Immunotherapy Failure. medRxiv. 2024 Jul 15. Özçam M, Lin DL, Gupta CL, Li A, Wheatley LM, Baloh CH, Sanda S, Jones SM, Lynch SV. PMID: 39072014; PMCID: PMC11275660.
      View in: PubMed   Mentions:
    2. Nasal and blood transcriptomic pathways underpinning the clinical response to grass pollen immunotherapy. J Allergy Clin Immunol. 2023 11; 152(5):1247-1260. Altman MC, Segnitz RM, Larson D, Jayavelu ND, Smith MT, Patel S, Scadding GW, Qin T, Sanda S, Steveling E, Eifan AO, Penagos M, Jacobson MR, Parkin RV, Shamji MH, Togias A, Durham SR. PMID: 37460024; PMCID: PMC10788383.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    3. Distinct trajectories distinguish antigen-specific T cells in peanut-allergic individuals undergoing oral immunotherapy. J Allergy Clin Immunol. 2023 07; 152(1):155-166.e9. Calise J, DeBerg H, Garabatos N, Khosa S, Bajzik V, Calderon LB, Aldridge K, Rosasco M, Ferslew BC, Zhu T, Smulders R, Wheatley LM, Laidlaw TM, Qin T, Chichili GR, Adelman DC, Farrington M, Robinson D, Jeong D, Jones SM, Sanda S, Larson D, Kwok WW, Baloh C, Nepom GT, Wambre E, IMPACT. PMID: 37003475; PMCID: PMC10330178.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    4. Gut Microbiome Membrane Lipids and Bile Acids Relate to Peanut Oral Immunotherapy Outcomes. Journal of Allergy and Clinical Immunology. 2023 Feb 1; 151(2):ab341. Ozcam OM, McCauley MK, Wheatley WL, Baloh BC, Sanda SS, Jones JS, Lynch LS. .
      View in: Publisher Site   Mentions:
    5. HLA-associated outcomes in peanut oral immunotherapy trials identify mechanistic and clinical determinants of therapeutic success. Front Immunol. 2022; 13:941839. Kanchan K, Shankar G, Huffaker MF, Bahnson HT, Chinthrajah RS, Sanda S, Manohar M, Ling H, Paschall JE, Toit GD, Ruczinski I, Togias A, Lack G, Nadeau KC, Jones SM, Nepom GT, Mathias RA. PMID: 36466872; PMCID: PMC9717393.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    6. Effects of combination treatment with tezepelumab and allergen immunotherapy on nasal responses to allergen: A randomized controlled trial. J Allergy Clin Immunol. 2023 01; 151(1):192-201. Corren J, Larson D, Altman MC, Segnitz RM, Avila PC, Greenberger PA, Baroody F, Moss MH, Nelson H, Burbank AJ, Hernandez ML, Peden D, Saini S, Tilles S, Hussain I, Whitehouse D, Qin T, Villarreal M, Sever M, Wheatley LM, Nepom GT, Sanda S, Immune Tolerance Network ITN057AD CATNIP Study Team. PMID: 36223848.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    7. IL-6-Driven pSTAT1 Response Is Linked to T Cell Features Implicated in Early Immune Dysregulation. Front Immunol. 2022; 13:935394. Lambert K, Diggins KE, Jones BE, Hundhausen C, Maerz MD, Hocking AM, Sanda S, Greenbaum CJ, Linsley PS, Cerosaletti K, Buckner JH. PMID: 35911690; PMCID: PMC9327741.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. Interpretation of Bone Mineral Density Z-Scores by Dual-Energy X-Ray Absorptiometry in Transgender and Gender Diverse Youth Prior to Gender-Affirming Medical Therapy. J Clin Densitom. 2022 Oct-Dec; 25(4):559-568. Lee JY, Fan B, Montenegro G, Long RK, Sanda S, Capodanno G, Schafer AL, Burghardt AJ, Rosenthal SM, Fung EB. PMID: 35941040; PMCID: PMC10149316.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Translating lessons learned on the role of HLA in immunological responses in LEAP to peanut OIT Trials: IMPACT and POISED. Journal of Allergy and Clinical Immunology. 2022 Feb 1; 149(2):ab314. Kanchan KK, Shankar SG, Huffaker HM, Bahnson BH, Chinthrajah CR, Sanda SS, Manohar MM, Du Toit DG, Ruczinski RI, Lack LG, Nadeau NK, Jones JS, Nepom NG, Mathias MR. .
      View in: Publisher Site   Mentions:
    10. Efficacy and safety of oral immunotherapy in children aged 1-3 years with peanut allergy (the Immune Tolerance Network IMPACT trial): a randomised placebo-controlled study. Lancet. 2022 01 22; 399(10322):359-371. Jones SM, Kim EH, Nadeau KC, Nowak-Wegrzyn A, Wood RA, Sampson HA, Scurlock AM, Chinthrajah S, Wang J, Pesek RD, Sindher SB, Kulis M, Johnson J, Spain K, Babineau DC, Chin H, Laurienzo-Panza J, Yan R, Larson D, Qin T, Whitehouse D, Sever ML, Sanda S, Plaut M, Wheatley LM, Burks AW, Immune Tolerance Network. PMID: 35065784; PMCID: PMC9119642.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimals
    11. IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes. JCI Insight. 2021 11 08; 6(21). Greenbaum CJ, Serti E, Lambert K, Weiner LJ, Kanaparthi S, Lord S, Gitelman SE, Wilson DM, Gaglia JL, Griffin KJ, Russell WE, Raskin P, Moran A, Willi SM, Tsalikian E, DiMeglio LA, Herold KC, Moore WV, Goland R, Harris M, Craig ME, Schatz DA, Baidal DA, Rodriguez H, Utzschneider KM, Nel HJ, Soppe CL, Boyle KD, Cerosaletti K, Keyes-Elstein L, Long SA, Thomas R, McNamara JG, Buckner JH, Sanda S, ITN058AI EXTEND Study Team. PMID: 34747368; PMCID: PMC8663550.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    12. Approaches to Establishing Tolerance in Immune Mediated Diseases. Front Immunol. 2021; 12:744804. Huffaker MF, Sanda S, Chandran S, Chung SA, St Clair EW, Nepom GT, Smilek DE. PMID: 34616405; PMCID: PMC8488342.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    13. Imatinib therapy for patients with recent-onset type 1 diabetes: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial. Lancet Diabetes Endocrinol. 2021 08; 9(8):502-514. Gitelman SE, Bundy BN, Ferrannini E, Lim N, Blanchfield JL, DiMeglio LA, Felner EI, Gaglia JL, Gottlieb PA, Long SA, Mari A, Mirmira RG, Raskin P, Sanda S, Tsalikian E, Wentworth JM, Willi SM, Krischer JP, Bluestone JA, Gleevec Trial Study Group. PMID: 34214479; PMCID: PMC8494464.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCTClinical Trials
    14. Diabetic ketoacidosis drives COVID-19 related hospitalizations in children with type 1 diabetes. J Diabetes. 2021 Aug; 13(8):681-687. Alonso GT, Ebekozien O, Gallagher MP, Rompicherla S, Lyons SK, Choudhary A, Majidi S, Pinnaro CT, Balachandar S, Gangat M, Curda Roberts AJ, Marks BE, Creo A, Sanchez J, Seeherunvong T, Jimenez-Vega J, Patel NS, Wood JR, Gabriel L, Sumpter KM, Wilkes M, Rapaport R, Cymbaluk A, Wong JC, Sanda S, Albanese-O'neill A. PMID: 33855813; PMCID: PMC8251108.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    15. Differential induction of allergen-specific IgA responses following timothy grass subcutaneous and sublingual immunotherapy. J Allergy Clin Immunol. 2021 10; 148(4):1061-1071.e11. Shamji MH, Larson D, Eifan A, Scadding GW, Qin T, Lawson K, Sever ML, Macfarlane E, Layhadi JA, Würtzen PA, Parkin RV, Sanda S, Harris KM, Nepom GT, Togias A, Durham SR. PMID: 33819508.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    16. Inequities in Diabetic Ketoacidosis Among Patients With Type 1 Diabetes and COVID-19: Data From 52 US Clinical Centers. J Clin Endocrinol Metab. 2021 03 25; 106(4):e1755-e1762. Ebekozien O, Agarwal S, Noor N, Albanese-O'Neill A, Wong JC, Seeherunvong T, Sanchez J, DeSalvo D, Lyons SK, Majidi S, Wood JR, Acharya R, Aleppo G, Sumpter KM, Cymbaluk A, Shah NA, Van Name M, Cruz-Aviles L, Alonso GT, Gallagher MP, Sanda S, Feuer AJ, Cossen K, Rioles N, Jones NY, Kamboj MK, Hirsch IB. PMID: 33410917; PMCID: PMC7928931.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    17. Sensitive detection of multiple islet autoantibodies in type 1 diabetes using small sample volumes by agglutination-PCR. PLoS One. 2020; 15(11):e0242049. Cortez FJ, Gebhart D, Robinson PV, Seftel D, Pourmandi N, Owyoung J, Bertozzi CR, Wilson DM, Maahs DM, Buckingham BA, Mills JR, Roforth MM, Pittock SJ, McKeon A, Page K, Wolf WA, Sanda S, Speake C, Greenbaum CJ, Tsai CT. PMID: 33186361; PMCID: PMC7665791.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsPHPublic Health
    18. Nasal allergen challenge and environmental exposure chamber challenge: A randomized trial comparing clinical and biological responses to cat allergen. J Allergy Clin Immunol. 2020 06; 145(6):1585-1597. Larson D, Patel P, Salapatek AM, Couroux P, Whitehouse D, Pina A, Johnson JL, Sever ML, Sanda S, Poyser J, Allio T, Scadding GW, Qin T, Shamji MH, Kwok WW, James EA, French D, Lelic A, Larché M, Altman MC, Togias A, Durham SR. PMID: 32169380; PMCID: PMC8958045.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    19. Effects of Combined Treatment with Cat Allergen Immunotherapy and Tezepelumab on Nasal Allergen Challenge. Journal of Allergy and Clinical Immunology. 2020 Feb 1; 145(2):ab336. Corren CJ, Wheatley WL, Sanda SS, Larson LD, Qin QT, Avila AP, Baroody BF, Greenberger GP, Hussain HI, Moss MM, Nelson NH, Saini SS, Tilles TS, Laurienzo LJ, Sever SM, Whitehouse WD, Yan YR, Nepom NG. .
      View in: Publisher Site   Mentions:
    20. Tolerance Development Following Oral Immunotherapy (OIT) in 1-3 Year Old Children with Peanut Allergy: Findings from the Immune Tolerance Network (ITN) IMPACT TRIAL. Journal of Allergy and Clinical Immunology. 2020 Feb 1; 145(2):ab338. Jones JS, Kim KE, Nadeau NK, Nowak-Wegrzyn NA, Wood WR, Sampson SH, Scurlock SA, Chinthrajan CS, Johnson JJ, Spain SK, Laurienzo LJ, Larson LD, Plaut PM, Qin QT, Sanda SS, Sever SM, Wheatley WL, Whitehouse WD, Yan YR, Burks BA. .
      View in: Publisher Site   Mentions:
    21. Survival in a bad neighborhood: pancreatic islets in cystic fibrosis. J Endocrinol. 2019 Feb 01. Norris AW, Ode KL, Merjaneh L, Sanda S, Yi Y, Sun X, Engelhardt JF, Hull RL. PMID: 30759072; PMCID: PMC6675675.
      View in: PubMed   Mentions: 28     Fields:    
    22. Hyaluronan levels are increased systemically in human type 2 but not type 1 diabetes independently of glycemic control. Matrix Biol. 2019 07; 80:46-58. Nagy N, Sunkari VG, Kaber G, Hasbun S, Lam DN, Speake C, Sanda S, McLaughlin TL, Wight TN, Long SR, Bollyky PL. PMID: 30196101; PMCID: PMC6401354.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    23. Islet Interleukin-1β Immunoreactivity Is an Early Feature of Cystic Fibrosis That May Contribute to β-Cell Failure. Diabetes Care. 2018 04; 41(4):823-830. Hull RL, Gibson RL, McNamara S, Deutsch GH, Fligner CL, Frevert CW, Ramsey BW, Sanda S. PMID: 29437698; PMCID: PMC5860832.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    24. Remodeling T cell compartments during anti-CD3 immunotherapy of type 1 diabetes. Cell Immunol. 2017 Sep; 319:3-9. Long SA, Thorpe J, Herold KC, Ehlers M, Sanda S, Lim N, Linsley PS, Nepom GT, Harris KM. PMID: 28844471; PMCID: PMC5614459.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    25. Increasing ICA512 autoantibody titers predict development of abnormal oral glucose tolerance tests. Pediatr Diabetes. 2018 03; 19(2):271-276. Sanda S, Type 1 Diabetes TrialNet Study Group. PMID: 28707353; PMCID: PMC5849060.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Acute hyperglycemia impairs IL-6 expression in humans. Immun Inflamm Dis. 2016 Mar; 4(1):91-7. Spindler MP, Ho AM, Tridgell D, McCulloch-Olson M, Gersuk V, Ni C, Greenbaum C, Sanda S. PMID: 27042306; PMCID: PMC4768063.
      View in: PubMed   Mentions: 8     Fields:    
    27. Avidity-dependent programming of autoreactive T cells in T1D. PLoS One. 2014; 9(5):e98074. Durinovic-Belló I, Gersuk VH, Ni C, Wu R, Thorpe J, Jospe N, Sanda S, Greenbaum CJ, Nepom GT. PMID: 24844227; PMCID: PMC4028311.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    28. Use of a "fuzzy logic" controller in a closed-loop artificial pancreas. Diabetes Technol Ther. 2013 Aug; 15(8):628-33. Mauseth R, Hirsch IB, Bollyky J, Kircher R, Matheson D, Sanda S, Greenbaum C. PMID: 23829285.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    29. Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials. Lancet. 2013 Jun 01; 381(9881):1905-15. Moran A, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R, Greenbaum CJ, Herold KC, Marks JB, Raskin P, Sanda S, Schatz D, Wherrett DK, Wilson DM, Krischer JP, Skyler JS, Type 1 Diabetes TrialNet Canakinumab Study Group, Pickersgill L, de Koning E, Ziegler AG, Böehm B, Badenhoop K, Schloot N, Bak JF, Pozzilli P, Mauricio D, Donath MY, Castaño L, Wägner A, Lervang HH, Perrild H, Mandrup-Poulsen T, AIDA Study Group. PMID: 23562090; PMCID: PMC3827771.
      View in: PubMed   Mentions: 177     Fields:    Translation:HumansCells
    30. CD4+ T cells recognize diverse epitopes within GAD65: implications for repertoire development and diabetes monitoring. Immunology. 2013 Mar; 138(3):269-79. Yang J, James EA, Sanda S, Greenbaum C, Kwok WW. PMID: 23228173; PMCID: PMC3573280.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    31. Correlation of TSH with the risk of paediatric thyroid carcinoma. Clin Endocrinol (Oxf). 2012 Aug; 77(2):316-22. Chiu HK, Sanda S, Fechner PY, Pihoker C. PMID: 22404106.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    32. Rapamycin/IL-2 combination therapy in patients with type 1 diabetes augments Tregs yet transiently impairs β-cell function. Diabetes. 2012 Sep; 61(9):2340-8. Long SA, Rieck M, Sanda S, Bollyky JB, Samuels PL, Goland R, Ahmann A, Rabinovitch A, Aggarwal S, Phippard D, Turka LA, Ehlers MR, Bianchine PJ, Boyle KD, Adah SA, Bluestone JA, Buckner JH, Greenbaum CJ, Diabetes TrialNet and the Immune Tolerance Network. PMID: 22721971; PMCID: PMC3425404.
      View in: PubMed   Mentions: 176     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    33. Through the fog: recent clinical trials to preserve β-cell function in type 1 diabetes. Diabetes. 2012 Jun; 61(6):1323-30. Greenbaum CJ, Schatz DA, Haller MJ, Sanda S. PMID: 22618767; PMCID: PMC3357268.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    34. A SNP in G6PC2 predicts insulin secretion in type 1 diabetes. Acta Diabetol. 2013 Jun; 50(3):459-62. Sanda S, Wei S, Rue T, Shilling H, Greenbaum C. PMID: 22438186.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    35. Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1. Proc Natl Acad Sci U S A. 2012 Mar 20; 109(12):E715-24. Kanter JE, Kramer F, Barnhart S, Averill MM, Vivekanandan-Giri A, Vickery T, Li LO, Becker L, Yuan W, Chait A, Braun KR, Potter-Perigo S, Sanda S, Wight TN, Pennathur S, Serhan CN, Heinecke JW, Coleman RA, Bornfeldt KE. PMID: 22308341; PMCID: PMC3311324.
      View in: PubMed   Mentions: 150     Fields:    Translation:HumansAnimalsCells
    36. Discovery of T cell antigens by high-throughput screening of synthetic minigene libraries. PLoS One. 2012; 7(1):e29949. Hondowicz BD, Schwedhelm KV, Kas A, Tasch MA, Rawlings C, Ramchurren N, McIntosh M, D'Amico LA, Sanda S, Standifer NE, Shendure J, Stone B. PMID: 22253836; PMCID: PMC3257230.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    37. Altered B cell homeostasis is associated with type I diabetes and carriers of the PTPN22 allelic variant. J Immunol. 2012 Jan 01; 188(1):487-96. Habib T, Funk A, Rieck M, Brahmandam A, Dai X, Panigrahi AK, Luning Prak ET, Meyer-Bahlburg A, Sanda S, Greenbaum C, Rawlings DJ, Buckner JH. PMID: 22105996; PMCID: PMC3670766.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansCellsCTClinical Trials
    38. Comment on: Atkinson. It's time to consider changing the rules: the rationale for rethinking control groups in clinical trials aimed at reversing type 1 diabetes. Diabetes 2011;60:361-363. Diabetes. 2011 Jun; 60(6):e17, author reply e18. Sanda S, Greenbaum CJ. PMID: 21617183; PMCID: PMC3114381.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    39. Short-term IL-1beta blockade reduces monocyte CD11b integrin expression in an IL-8 dependent fashion in patients with type 1 diabetes. Clin Immunol. 2010 Aug; 136(2):170-3. Sanda S, Bollyky J, Standifer N, Nepom G, Hamerman JA, Greenbaum C. PMID: 20483667.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    40. A T1D-associated Variant of PTPN2 Correlates with Decreased IL-2/IL-15 Responsiveness, Reduced FOXP3 Expression and Altered CD8 T Cell Differentiation. Clinical Immunology. 2010 Jan 1; 135:s118. Long LS, Cerosaletti CK, Shilling SH, Bollyky BP, Rawlings RD, Sanda SS, Buckner BJ. .
      View in: Publisher Site   Mentions:
    41. High-throughput Screening for CD8+ T Cell Epitopes Targeted in Type 1 Diabetes. Clinical Immunology. 2010 Jan 1; 135:s19. Hondowicz HB, Schwedhelm SK, Kas KA, Tasch TM, Ramchurren RN, Standifer SN, Sanda SS, Rawlings RC, Shendure SJ, Stone SB. .
      View in: Publisher Site   Mentions:
    42. Reduced CD11b Integrin Expression with Short-term Administration of an IL-1R Antagonist in Type 1 Diabetes Patients. Clinical Immunology. 2010 Jan 1; 135:s106-s107. Sanda SS, Bollyky BJ, Nepom NG, Hamerman HJ, Greenbaum GC. .
      View in: Publisher Site   Mentions:
    43. Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects. Diabetes. 2010 Feb; 59(2):407-15. Long SA, Cerosaletti K, Bollyky PL, Tatum M, Shilling H, Zhang S, Zhang ZY, Pihoker C, Sanda S, Greenbaum C, Buckner JH. PMID: 19875613; PMCID: PMC2809970.
      View in: PubMed   Mentions: 145     Fields:    Translation:HumansCells
    44. Diminished IL-2 responsiveness and FOXP3 expression in T1D subjects is revealed by a disease-associated variant of PTPN2 (49.1). The Journal of Immunology. 2009 Apr 1; 182(1_Supplement):49.1-49.1. Long LS, Bollyky BP, Cerosaletti CK, Shilling SH, Pihoker PC, Sanda SS, Greenbaum GC, Buckner BJ. .
      View in: Publisher Site   Mentions:
    45. Functional islet-specific Treg can be generated from CD4+CD25- T cells of healthy and type 1 diabetic subjects. Eur J Immunol. 2009 Feb; 39(2):612-20. Long SA, Walker MR, Rieck M, James E, Kwok WW, Sanda S, Pihoker C, Greenbaum C, Nepom GT, Buckner JH. PMID: 19180473; PMCID: PMC2743096.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    46. T.128. Short-term Administration of Anakinra does not Appear to Affect Stimulated C-peptide Responses Acutely in Patients with Type 1 Diabetes. Clinical Immunology. 2009 Jan 1; 131:s89. Sanda SS, Bollyky BJ, Burwell BE, Standifer SN, Nepom NG, Greenbaum GC. .
      View in: Publisher Site   Mentions:
    47. F.69. Selection of Antigen Specific Autoreactive T Cells is Influenced by INS-VNTR Genotype. Clinical Immunology. 2009 Jan 1; 131:s112. Durinovic-Bello DI, Wu WR, Sanda SS, Nepom NG. .
      View in: Publisher Site   Mentions:
    48. OR.62. Impaired IL-2 Responsiveness and Treg Persistence in T1D is Revealed by Disease-Associated Variants in PTPN2. Clinical Immunology. 2009 Jan 1; 131:s26-s27. Long LS, Bollyky BP, Cerosaletti CK, Shilling SH, Pihoker PC, Sanda SS, Greenbaum GC, Buckner BJ. .
      View in: Publisher Site   Mentions:
    49. The effector T cells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T cells. J Immunol. 2008 Nov 15; 181(10):7350-5. Schneider A, Rieck M, Sanda S, Pihoker C, Greenbaum C, Buckner JH. PMID: 18981158; PMCID: PMC2597079.
      View in: PubMed   Mentions: 146     Fields:    Translation:HumansCells
    50. Type 1 diabetes mellitus: primary, secondary, and tertiary prevention. Mt Sinai J Med. 2008 Aug; 75(4):385-97. Bollyky J, Sanda S, Greenbaum CJ. PMID: 18729155.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    51. Autosomal dominant hypoparathyroidism with severe hypomagnesemia and hypocalcemia, successfully treated with recombinant PTH and continuous subcutaneous magnesium infusion. J Pediatr Endocrinol Metab. 2008 Apr; 21(4):385-91. Sanda S, Schlingmann KP, Newfield RS. PMID: 18556971.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    52. Islet antigen specific IL-10+ immune responses but not CD4+CD25+FoxP3+ cells at diagnosis predict glycemic control in type 1 diabetes. Clin Immunol. 2008 May; 127(2):138-43. Sanda S, Roep BO, von Herrath M. PMID: 18304876.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    53. A child with pericardial effusion and cardiac tamponade due to previously unrecognized hypothyroidism. J Natl Med Assoc. 2007 Dec; 99(12):1411-3. Sanda S, Newfield RS. PMID: 18229779; PMCID: PMC2575930.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    54. Type 1 diabetes as a relapsing-remitting disease? Nat Rev Immunol. 2007 Dec; 7(12):988-94. von Herrath M, Sanda S, Herold K. PMID: 17982429.
      View in: PubMed   Mentions: 121     Fields:    Translation:HumansAnimalsCells
    55. Reduced Foxp3 and Interleukin 10 Expression During the Partial Remission Phase of Type 1 Diabetes in Children. Clinical Immunology. 2007 Jan 1; 123:s16. Sanda SS, Roep RB, von Herrath vM. .
      View in: Publisher Site   Mentions:
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