Girish Vyas, PhD

Title(s)Professor Emeritus, Laboratory Medicine
SchoolSchool of Medicine
Address513 Parnassus Avenue, HSW, #1201D
San Francisco CA 94143
ORCID ORCID Icon0000-0003-1090-4911 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of BombayPh.D.1965Pathology, G.S. Medical College
    Royal College of PathologistsF.R.C.Path.2012Virology, Immunology, Transfusion Medicine
    Collapse Awards and Honors
    International Society of Blood Transfusion1969Jean Julliard Prize
    Pasteur Institute, Paris1980American Fulbright Visiting Scholar

    Collapse Overview 
    Collapse Overview
    Girish N. Vyas, Ph.D. (Univ. of Bombay, 1965), F.R.C.Path. (London, 2012), completed a postdoctoral fellowship at Case-WRU in Cleveland, Ohio in 1967. Then he joined UCSF School of Medicine as a Lecturer in Hematology and Immunology Unit of the Department of Medicine. He moved to Department of Laboratory Medicine as an Assistant Professor and served as Director of Blood Bank at UCSF Medical Center from 1969-89. During his sabbatical leave in 1972-73 he worked as a visiting scientist at Weizmann Institute in Israel and Walter and Eliza Hall Institute in Australia. In 1980 he got an American Fulbright Senior Scholar Award to work with Pierre Tiollais on molecular biology of HBV at the Pasteur Institute, Paris. During his four decades of faculty service at UCSF he trained 18 graduate and 46 postdoctoral scholars. His seminal contributions to our current knowledge about IgA deficiency and anaphylactic transfusion reactions, HBsAg structure, HBV vaccine and immune globulins in perinatal prevention of mother to child transmission of infection, screening and elimination of transfusion-transmitted HBV, HCV, HIV to enhance transfusion safety, and sustained commitment to immune prevention of HIV/AIDS. These contributions earned him the honor as a "Pioneer and Pathfinder in Transfusion Medicine" in 2008. He has edited 12 books and monographs and published 225 original papers. He has served on several committees of NAS-NRC, NIH, CDC, FDA, WHO, AABB, ASH, and UNDP and as the Editor-in-Chief of Biological. Currently he is an Emeritus Professor of Laboratory Medicine at UCSF and full-time CEO of TheraBiol, Inc., a start-up biotech company launched in 2012 for R&D of antibodies for prevention and treatment of persistent infections, HIV being the first target.

    Collapse Research 
    Collapse Research Activities and Funding
    NIH R01HL053384Sep 30, 1994 - Aug 31, 2000
    Role: Principal Investigator
    NIH R01HL041361Jul 1, 1988 - Mar 31, 1992
    Role: Principal Investigator
    NIH/NHLBI N01HB067020Sep 30, 1986 - Sep 30, 1995
    Role: Principal Investigator
    NIH/NHLBI N01HB067024Sep 30, 1986 - Sep 30, 1995
    Role: Principal Investigator
    NIH P01HL036589Jul 1, 1986 - Dec 31, 1991
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000079Dec 1, 1974 - Mar 31, 2009
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Fifty years of advancing biologicals and beyond. Biologicals. 2024 Feb; 85:101727. Gupta R, Elwyn G, Vyas G, Thorpe R, Baylor N. PMID: 37992427.
      View in: PubMed   Mentions:    Fields:    
    2. Eradicating hepatitis B virus: The critical role of preventing perinatal transmission. Biologicals. 2017 Nov; 50:3-19. Stevens CE, Toy P, Kamili S, Taylor PE, Tong MJ, Xia GL, Vyas GN. PMID: 28870397.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCellsPHPublic Health
    3. Remembering James W. Mosley, MD (1929-2015), and his legacy in transfusion safety. Transfusion. 2016 Apr; 56(4):996-8. Busch MP, Vyas GN. PMID: 27079314.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    4. Possible transmission of human immunodeficiency virus-1 infection from an elite controller to a patient who progressed to acquired immunodeficiency syndrome: a case report. J Med Case Rep. 2012 Sep 11; 6:291. Killian MS, Vyas GN, Mehta R, Young K, Ebrahim O. PMID: 22967353; PMCID: PMC3469400.
      View in: PubMed   Mentions: 1     Fields:    
    5. Adverse effects of plasma transfusion. Transfusion. 2012 May; 52 Suppl 1:65S-79S. Pandey S, Vyas GN. PMID: 22578374; PMCID: PMC3356109.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansCells
    6. The life and legacy of Alfred M. Prince, M. D. (1928-2011). Biologicals. 2012 Jan; 40(1):1-2. Vyas GN, Grady GF. PMID: 22408790.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. Derivation of non-infectious envelope proteins from virions isolated from plasma negative for HIV antibodies. Biologicals. 2012 Jan; 40(1):15-20. Vyas GN, Stoddart CA, Killian MS, Brennan TV, Goldberg T, Ziman A, Bryson Y. PMID: 22192456; PMCID: PMC4861611.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    8. Pooled peripheral blood mononuclear cells provide an optimized cellular substrate for human immunodeficiency virus Type 1 isolation during acute infection. Transfusion. 2011 Feb; 51(2):333-7. Lai-Hipp C, Goldberg T, Scott E, Ziman A, Vyas G. PMID: 20796251.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    9. Unconventional journals: research ramifications. Science. 2010 Apr 23; 328(5977):427. Vyas GN. PMID: 20413475.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    10. Transfusion medicine and safety. Biologicals. 2009 Apr; 37(2):62-70. Dodd R, Kurt Roth W, Ashford P, Dax EM, Vyas G. PMID: 19230706.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    11. Preparation and use of therapeutic antibodies primarily of human origin. Biologicals. 2008 Nov; 36(6):363-74. Stiehm ER, Keller MA, Vyas GN. PMID: 18789721.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    12. Participating in the evolution of transfusion medicine from a dispensary into a discipline. Transfus Med Rev. 2008 Apr; 22(2):162-7. Vyas GN. PMID: 18353255; PMCID: PMC2361154.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. A hollow-fiber bioreactor for expanding HIV-1 in human lymphocytes used in preparing an inactivated vaccine candidate. Biologicals. 2007 Oct; 35(4):227-33. Leong M, Babbitt W, Vyas G. PMID: 17728144.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    14. Blood-transmitted prions and variant Creutzfeldt-Jakob disease. Biologicals. 2007 Apr; 35(2):75-7. Grady GF, Vyas GN. PMID: 17317213.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Hepatitis B immune globulin preparations and use in liver transplantation. Clin Liver Dis. 2003 Aug; 7(3):537-50. Terrault NA, Vyas G. PMID: 14509525.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    16. Hepatitis B virus in non-hepatocytes. Lancet. 1983 Oct 15; 2(8355):920. Blum HE, Vyas GN. PMID: 6137741.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    17. Partial amino acid sequence of two major component polypeptides of hepatitis B surface antigen. Proc Natl Acad Sci U S A. 1977 Apr; 74(4):1530-4. Peterson DL, Roberts IM, Vyas GN. PMID: 266193; PMCID: PMC430823.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    18. Biochemical characterization of hepatitis B surface antigen in relation to serologic activity. J Biol Stand. 1976; 4(4):295-304. Rao KR, Vyas GN. PMID: 993216.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    19. T-cell dependence of immune response to hepatitis B antigen in mice. Nature. 1975 Apr 17; 254(5501):606-7. Roberts IM, Bernard CC, Vyas GN, Mackay IR. PMID: 1079326.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    20. Hepatitis B surface antigen (HBs Ag): tryptophan content and biological activity. J Gen Virol. 1974 Sep; 24(3):571-3. Rao KR, Vyas GN. PMID: 4427108.
      View in: PubMed   Mentions: 2     Fields:    
    21. Structure and activity of hepatitis B antigen (HBAg). 2. Amino acid composition of an active subunit of HBAg. Microbios. 1974 May; 10(40):233-8. Rao KR, Vyas GN. PMID: 4854427.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Structure and activity of hepatitis B antigen (HBAg). 1. Studies on some conformational aspects and chemical modification of hepatitis B antigen. Microbios. 1974 Mar-Apr; 9(36):239-45. Rao KR, Vyas GN. PMID: 4134655.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    23. Hepatitis B antigen activity in protein subunits produced by sonicaation. Nat New Biol. 1973 Feb 21; 241(112):240-1. Rao KR, Vyas GN. PMID: 4512480.
      View in: PubMed   Mentions: 8     Fields:    
    24. Australia antigen (hepatitis B antigen): a conformational antigen dependent on disulfide bonds. Science. 1972 Dec 22; 178(4067):1300-1. Vyas GN, Rao KR, Ibrahim AB. PMID: 4118259.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCellsPHPublic Health
    25. Study of a French family with a new variant of blood group A: A lae . Am J Hum Genet. 1972 Jan; 24(1):11-7. Schuh V, Vyas GN, Fudenberg HH. PMID: 5012687; PMCID: PMC1762156.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    26. Passive haemagglutination test for anti-rhinovirus antibodies. Nat New Biol. 1971 May 26; 231(21):101-4. Faulk WP, Vyas GN, Phillips CA, Fudenberg HH, Chism K. PMID: 4325709.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    27. Intrauterine isoimmunization caused by maternal IgA crossing the placenta. Nature. 1970 Jan 17; 225(5229):275-6. Vyas GN, Levin AS, Fudenberg HH. PMID: 5308068.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    28. Am(1), the first genetic marker of human immunoglobulin A. Proc Natl Acad Sci U S A. 1969 Dec; 64(4):1211-6. Vyas GN, Fudenberg HH. PMID: 4195395; PMCID: PMC223270.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    29. Human antibodies to human IgA globulins. Immunochemistry. 1968 Mar; 5(2):203-6. Fudenberg HH, Gold ER, Vyas GN, Mackenzie MR. PMID: 4103908.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    30. A new rapid method for genetic typing of human immunoglobulins. J Immunol. 1968 Feb; 100(2):274-9. Vyas GN, Fudenberg HH, Pretty HM, Gold ER. PMID: 4170633.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    31. Hemagglutinating substances in plant seeds. J Postgrad Med. 1967 Jan; 13(1):29-36. Sathe MS, Vyas GN, Bhatia HM, Purandare NM. PMID: 6035742.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    33. Suppression of gene A in two cases of anti-H (Bombay bloods) in a family from South Canara. J Assoc Physicians India. 1962 Dec; 10:745-8. VYAS GN, PANDIT HM, PURANDARE NM. PMID: 13998077.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. Study of blood groups, abnormal hemoglobins and other genetical characters in some tribes of Gujarat. Am J Phys Anthropol. 1962 09; 20(3):255-65. Vyas GN, Bhatia HM, Sukumaran PK, Balkrishnan V, Sanghvi LD. PMID: 13998076.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    35. Study of blood groups and other genetical characters in six Gujarati endogamous groups in Western India. Ann Hum Genet. 1958 May; 22(3):185-99. VYAS GN, BHATIA HM, BANKER DD, PURANDARE NM. PMID: 13534204.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    36. Chalkones from quinacetophenone monomethyl ether. Curr Sci. 1950 Oct; 19(10):318-9. VYAS GN, SHAH NM. PMID: 14792992.
      View in: PubMed   Mentions:    Fields:    
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