Loading...

Pearl Toy, MD

Title(s)Professor Emeritus, Laboratory Medicine
SchoolSchool of Medicine
Address521 Parnassus Avenue
San Francisco CA 94117
Phone--
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    Smith College, Northampton, MAB.A., Phi Beta Kappa1969Biochemistry
    Stanford Medical School, Stanford, CAM.D., Alpha Omega Alpha1973Medicine
    Collapse Awards and Honors
    California Blood Bank Society2017Herbert Perkins & George Garratty Memorial Lectureship Award
    International Society Blood Transfusion, Am Assoc Blood Banks & British Blood Transfusion Society2007International Woman in Transfusion Medicine Award
    Harvard Medical School Transfusion Medicine Joint Program2007Inaugural Transfusion Medicine Margot S. Kruskall Lectureship
    UCSF2005Nominee, Chancellor's Award for Public Service
    NIH2000  - 2004Member, NHLBI Advisory Council
    TCU/Cliburn Institute, Fort Worth, Texas1999Winner, Amateur Piano Concerto Competition
    Various orchestras1997  - 2002Soloist, the 5 Beethoven piano concertos
    NHLBI, NIH1996  - 2011PI, Transfusion Medicine Specialized Center of Research SCOR grants (3 consecutive 5-yr awards)
    Smith College, Northampton, MA1991Smith College Medal
    UCSF Academic Senate1985Distinguished Teaching Award
    NHLBI, NIH1983  - 1988Transfusion Medicine Academic Award
    UCSF Department of Laboratory Medicine1983Faculty Teaching Award
    Stanford University School of Medicine1973Alpha Omega Alpha
    Smith College, Northampton, MA1968Phi Beta Kappa (Jr year), Sigma Xi

    Collapse Overview 
    Collapse Overview
    Primary Board Certification: Internal Medicine
    Subspecialties: Hematology, Transfusion Medicine

    1980-2010: Chief, Blood Bank, UCSF (1980-1992 SF General, 1991-2010 Moffitt-Long Hospital)

    1998-present: Founder and Director of the noontime Chancellor's Concert Series that brings free, high-quality, live classical music to the all-science UCSF campus.



    1980-present: Prevention of diseases transmitted by blood and blood transfusion:

    1. Prevention of hepatitis B transmission from mother-to-infant, by perinatal administration of hepatitis B immunoglobulin and hepatitis B vaccine to infants of carrier mothers. After this work was published and provided evidence that vaccination of infants was safe and effective, the US Advisory Committee on Immunization Practices recommended routine hepatitis B vaccination for infants in 1991.

    REF: Stevens CE, Toy PT, Tong MJ, Taylor PE, Vyas GN, Nair PV, Gudavalli M, Krugman S. Perinatal hepatitis B virus transmission in the United States. Prevention by passive-active immunization. JAMA. 1985 Mar 22-29; 253(12):1740-5.

    2. Prevention of transfusion-associated diseases associated with transfusion by the use of autologous blood.

    REF: Toy PT, Strauss RG, Stehling LC, Sears R, Price TH, Rossi EC, Collins ML, Crowley JP, Eisenstaedt RS, Goodnough LT, et al. Predeposited autologous blood for elective surgery. A national multicenter study. N Engl J Med. 1987 Feb 26; 316(9):517-20.

    3. Prevention of unnecessary plasma transfusion, by determining that there is no increased risk of bleeding in patients with mild coagulopathy who underwent percutaneous needle procedures.

    REF: McVay PA, Toy PT. Lack of increased bleeding after liver biopsy in patients with mild hemostatic abnormalities. Am J Clin Pathol. 1990 Dec; 94(6):747-53.

    REF: McVay PA, Toy PT. Lack of increased bleeding after paracentesis and thoracentesis in patients with mild coagulation abnormalities. Transfusion. 1991 Feb; 31(2):164-71.

    4. Prevention of bleeding from dilutional coagulopathy in trauma patients massively transfused with packed red blood cells, by earlier transfusion of plasma and/or whole blood.

    REF: Leslie SD, Toy PT. Laboratory hemostatic abnormalities in massively transfused patients given red blood cells and crystalloid. Am J Clin Pathol. 1991 Dec; 96(6):770-3.

    REF: San Francisco General Hospital Blood Bank procedures


    5. Prevention of unnecessary transfusions by physician education and prospective review of blood orders.

    REF: Toy PT. Audit and education in transfusion medicine. Vox Sang. 1996; 70(1):1-5.

    REF: UCSF Blood Bank procedures

    6. Prevention of unnecessary red blood cell transfusion, by examining the red blood cell transfusion trigger level. We determined that only hemoglobin levels below 7 g/dL are associated with organ impairment (cognitive dysfunction) during acute normovolemic anemia in normal humans.

    REF: Weiskopf RB, Feiner J, Hopf HW, Viele MK, Watson JJ, Kramer JH, Ho R, Toy P. Oxygen reverses deficits of cognitive function and memory and increased heart rate induced by acute severe isovolemic anemia. Anesthesiology. 2002 Apr; 96(4):871-7.


    7. Prevention of hyperkalemia (high potassium levels) and associated cardiac abnormalities in pediatric cardiac surgery patients, by washing stored red blood cells prior to transfusion on the morning of surgery.

    REF: Weiskopf RB, Schnapp S, Rouine-Rapp K, Bostrom A, Toy P. Extracellular potassium concentrations in red blood cell suspensions after irradiation and washing. Transfusion. 2005 Aug; 45(8):1295-301.

    REF: UCSF Blood Bank procedures

    8. Prevention of exsanguination in acutely bleeding hospitalized patients, by establishing an Emergency Release procedure so that blood and blood components are rapidly available.

    REF: Weiskopf RB, Webb M, Stangle D, Klinbergs G, Toy P. A procedure for rapid issue of red cells for emergency use. Arch Pathol Lab Med. 2005 Apr; 129(4):492-6.

    REF: UCSF Blood Bank procedures

    9. Prevention of most hemolytic transfusion reactions associated with transfusion of Group O plasma, by not transfusing group O plasma to group A and AB patients (most ABO hemolytic reactions associated with transfusion of group O plasma are in group A patients, and rarely in group B patients).

    REF: UCSF Blood Bank Procedures

    10. Prevention of transfusion-related acute lung injury (TRALI) by establishing a clinical definition, determining the transfusion and patient risk factors, and observing the efficacy of transfusing plasma from predominantly male donors in reducing TRALI incidence.

    REF: Toy P, Popovsky MA, Abraham E, Ambruso DR, Holness LG, Kopko PM, McFarland JG, Nathens AB, Silliman CC, Stroncek D. Transfusion-related acute lung injury: definition and review. Crit Care Med. 2005 Apr; 33(4):721-6.

    REF: Toy P, Gajic O, Bacchetti P, Looney MR, Gropper MA, Hubmayr R, Lowell CA, Norris PJ, Murphy EL, Weiskopf RB, Wilson G, Koenigsberg M, Lee D, Schuller R, Wu P, Grimes B, Gandhi MJ, Winters JL, Mair D, Hirschler N, Sanchez Rosen R, Matthay MA. Transfusion-related acute lung injury: incidence and risk factors. Blood. 2012 Feb 16; 119(7):1757-67.

    11. Prevention of TRALI in pediatric patients undergoing spine surgery, by identifying transfusion of maternal blood as an important risk factor.

    REF: Dunbar N, Cooke M, Diab M, Toy P. Transfusion-related acute lung injury after transfusion of maternal blood: a case-control study. Spine (Phila Pa 1976). 2010 Nov 1; 35(23):E1322-7.

    REF: UCSF Blood Donor Center procedures

    12. Prevention of septic platelet transfusion reactions being mistaken for TRALI.

    REF: Rollins MD, Molofsky AB, Nambiar A, Pandey S, Weiskopf RB, Toy P. Two septic transfusion reactions presenting as transfusion-related acute lung injury from a split plateletpheresis unit. Crit Care Med. 2012 Aug; 40(8):2488-91.

    Collapse Research 
    Collapse Research Activities and Funding
    Transfusion and Lung Injury
    NIH/NHLBI P50HL081027Sep 30, 2005 - Aug 31, 2011
    Role: Principal Investigator
    TRANSFUSION BIOLOGY AND MEDICINE
    NIH/NHLBI P50HL054476Feb 1, 1996 - Dec 31, 2006
    Role: Principal Investigator
    TRANSFUSION REQUIREMENTS FOR ELECTIVE SURGERY PROCEDURES
    NIH/NHLBI R03HL050280Apr 1, 1994 - Mar 31, 1998
    Role: Principal Investigator
    MODEL AUTOLOGOUS PREDEPOSIT BLOOD DONATION PROGRAM
    NIH/NHLBI R01HL036715Apr 1, 1987 - Mar 31, 1993
    Role: Principal Investigator
    SCIENTIFIC REVIEW AND EVALUATION AWARD
    NIH/NHLBI U09HL007541Jul 1, 1985 - Jun 30, 1996
    Role: Co-Principal Investigator
    TRANSFUSION MEDICINE
    NIH/NHLBI K07HL001270Sep 30, 1983 - Sep 29, 1988
    Role: Principal Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000079Dec 1, 1974 - Sep 29, 2006
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Complement activation on endothelium initiates antibody-mediated acute lung injury. J Clin Invest. 2020 Jul 30. Cleary SJ, Kwaan N, Tian JJ, Calabrese DR, Mallavia B, Magnen M, Greenland JR, Urisman A, Singer JP, Hays SR, Kukreja J, Hay AM, Howie HL, Toy P, Lowell CA, Morrell CN, Zimring JC, Looney MR. PMID: 32730229.
      View in: PubMed   Mentions:    Fields:    
    2. Update on transfusion-related acute lung injury. Clin Adv Hematol Oncol. 2019 Jul; 17(7):378-381. Toy P. PMID: 31449502.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. An update of the transfusion-related acute lung injury (TRALI) definition. Transfus Clin Biol. 2019 Nov; 26(4):354-356. Vlaar APJ, Toy P, Fung M, Looney MR, Juffermans NP, Bux J, Bolton-Maggs P, Peters AL, Silliman CC, Kor DJ, Kleinman S. PMID: 31221537.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. A consensus redefinition of transfusion-related acute lung injury. Transfusion. 2019 07; 59(7):2465-2476. Vlaar APJ, Toy P, Fung M, Looney MR, Juffermans NP, Bux J, Bolton-Maggs P, Peters AL, Silliman CC, Kor DJ, Kleinman S. PMID: 30993745.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    5. Antibodies associated with TRALI: differences in clinical relevance. Transfusion. 2019 03; 59(3):1147-1151. Kopko PM, Bux J, Toy P. PMID: 30548883.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Eradicating hepatitis B virus: The critical role of preventing perinatal transmission. Biologicals. 2017 Nov; 50:3-19. Stevens CE, Toy P, Kamili S, Taylor PE, Tong MJ, Xia GL, Vyas GN. PMID: 28870397.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    7. Differentiating pulmonary transfusion reactions using recipient and transfusion factors. Transfusion. 2017 07; 57(7):1684-1690. Roubinian NH, Looney MR, Keating S, Kor DJ, Lowell CA, Gajic O, Hubmayr R, Gropper M, Koenigsberg M, Wilson GA, A Matthay M, Toy P, Murphy EL. PMID: 28470756.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    8. Proposed revised nomenclature for transfusion-related acute lung injury. Transfusion. 2017 03; 57(3):709-713. Toy P, Kleinman SH, Looney MR. PMID: 28019007.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Reply to concerns regarding dropping the term "possible TRALI". Transfusion. 2016 09; 56(9):2394-5. Toy P, Kleinman SH, Looney MR. PMID: 27624212.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. A Clinical Trial to Detect Subclinical Transfusion-induced Lung Injury during Surgery. Anesthesiology. 2015 Jul; 123(1):126-35. Feiner JR, Gropper MA, Toy P, Lieberman J, Twiford J, Weiskopf RB. PMID: 25946480.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Cytokines and clinical predictors in distinguishing pulmonary transfusion reactions. Transfusion. 2015 Aug; 55(8):1838-46. Roubinian NH, Looney MR, Kor DJ, Lowell CA, Gajic O, Hubmayr RD, Gropper MA, Koenigsberg M, Wilson GA, Matthay MA, Toy P, Murphy EL. PMID: 25702590.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    12. Male-predominant plasma transfusion strategy for preventing transfusion-related acute lung injury: a systematic review. Crit Care Med. 2015 Jan; 43(1):205-25. Schmickl CN, Mastrobuoni S, Filippidis FT, Shah S, Radic J, Murad MH, Toy P, Gajic O. PMID: 25514705.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    13. Recipient clinical risk factors predominate in possible transfusion-related acute lung injury. Transfusion. 2015 May; 55(5):947-52. Toy P, Bacchetti P, Grimes B, Gajic O, Murphy EL, Winters JL, Gropper MA, Hubmayr RD, Matthay MA, Wilson G, Koenigsberg M, Lee DC, Hirschler NV, Lowell CA, Schuller RM, Gandhi MJ, Norris PJ, Mair DC, Sanchez Rosen R, Looney MR. PMID: 25488517.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    14. Prospective study on the clinical course and outcomes in transfusion-related acute lung injury*. Crit Care Med. 2014 Jul; 42(7):1676-87. Looney MR, Roubinian N, Gajic O, Gropper MA, Hubmayr RD, Lowell CA, Bacchetti P, Wilson G, Koenigsberg M, Lee DC, Wu P, Grimes B, Norris PJ, Murphy EL, Gandhi MJ, Winters JL, Mair DC, Schuller RM, Hirschler NV, Rosen RS, Matthay MA, Toy P. PMID: 24776608.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    15. Risk factors and outcomes in transfusion-associated circulatory overload. Am J Med. 2013 Apr; 126(4):357.e29-38. Murphy EL, Kwaan N, Looney MR, Gajic O, Hubmayr RD, Gropper MA, Koenigsberg M, Wilson G, Matthay M, Bacchetti P, Toy P. PMID: 23357450.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    16. Lot-to-lot variability in HLA antibody screening using a multiplexed bead-based assay. Transfusion. 2013 Sep; 53(9):1940-7. Gandhi MJ, Carrick DM, Jenkins S, De Goey S, Ploeger NA, Wilson GA, Lee JH, Winters JL, Stubbs JR, Toy P, Norris PJ. PMID: 23305156.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    17. Electronic health record surveillance algorithms facilitate the detection of transfusion-related pulmonary complications. Transfusion. 2013 Jun; 53(6):1205-16. Clifford L, Singh A, Wilson GA, Toy P, Gajic O, Malinchoc M, Herasevich V, Pathak J, Kor DJ. PMID: 22934792.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansPHPublic Health
    18. Two septic transfusion reactions presenting as transfusion-related acute lung injury from a split plateletpheresis unit. Crit Care Med. 2012 Aug; 40(8):2488-91. Rollins MD, Molofsky AB, Nambiar A, Pandey S, Weiskopf RB, Toy P. PMID: 22809916.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    19. Supporting Latino communities' natural helpers: a case study of promotoras in a research capacity building course. J Immigr Minor Health. 2012 Aug; 14(4):657-63. Otiniano AD, Carroll-Scott A, Toy P, Wallace SP. PMID: 21901447.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    20. Transfusion reactions: newer concepts on the pathophysiology, incidence, treatment, and prevention of transfusion-related acute lung injury. Crit Care Clin. 2012 Jul; 28(3):363-72, v. Sayah DM, Looney MR, Toy P. PMID: 22713611.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    21. Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury. J Clin Invest. 2012 Jul; 122(7):2661-71. Caudrillier A, Kessenbrock K, Gilliss BM, Nguyen JX, Marques MB, Monestier M, Toy P, Werb Z, Looney MR. PMID: 22684106.
      View in: PubMed   Mentions: 247     Fields:    Translation:HumansAnimalsCells
    22. Results from the Data & Democracy initiative to enhance community-based organization data and research capacity. Am J Public Health. 2012 Jul; 102(7):1384-91. Carroll-Scott A, Toy P, Wyn R, Zane JI, Wallace SP. PMID: 22594748.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    23. Fresh and stored red blood cell transfusion equivalently induce subclinical pulmonary gas exchange deficit in normal humans. Anesth Analg. 2012 Mar; 114(3):511-9. Weiskopf RB, Feiner J, Toy P, Twiford J, Shimabukuro D, Lieberman J, Looney MR, Lowell CA, Gropper MA. PMID: 22262647.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    24. Transfusion-related acute lung injury: incidence and risk factors. Blood. 2012 Feb 16; 119(7):1757-67. Toy P, Gajic O, Bacchetti P, Looney MR, Gropper MA, Hubmayr R, Lowell CA, Norris PJ, Murphy EL, Weiskopf RB, Wilson G, Koenigsberg M, Lee D, Schuller R, Wu P, Grimes B, Gandhi MJ, Winters JL, Mair D, Hirschler N, Sanchez Rosen R, Matthay MA. PMID: 22117051.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansPHPublic Health
    25. High oxygen partial pressure decreases anemia-induced heart rate increase equivalent to transfusion. Anesthesiology. 2011 Sep; 115(3):492-8. Feiner JR, Finlay-Morreale HE, Toy P, Lieberman JA, Viele MK, Hopf HW, Weiskopf RB. PMID: 21768873.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    26. Effectiveness of manual physical therapy in the treatment of cervical radiculopathy: a systematic review. J Man Manip Ther. 2011 Aug; 19(3):135-42. Boyles R, Toy P, Mellon J, Hayes M, Hammer B. PMID: 22851876.
      View in: PubMed   Mentions: 14     Fields:    
    27. Current problems and future directions of transfusion-induced alloimmunization: summary of an NHLBI working group. Transfusion. 2011 Feb; 51(2):435-41. Zimring JC, Welniak L, Semple JW, Ness PM, Slichter SJ, Spitalnik SL. PMID: 21251006.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    28. The current practice of orthopaedic oncology in North America. Clin Orthop Relat Res. 2010 Nov; 468(11):2840-53. White J, Toy P, Gibbs P, Enneking W, Scarborough M. PMID: 20532714.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    29. Transfusion-related acute lung injury after transfusion of maternal blood: a case-control study. Spine (Phila Pa 1976). 2010 Nov 01; 35(23):E1322-7. Dunbar N, Cooke M, Diab M, Toy P. PMID: 20938390.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    30. A multidisciplinary "think tank": the top 10 clinical trial opportunities in transfusion medicine from the National Heart, Lung, and Blood Institute-sponsored 2009 state-of-the-science symposium. Transfusion. 2011 Apr; 51(4):828-41. Josephson CD, Glynn SA, Kleinman SH, Blajchman MA. PMID: 21496044.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    31. Clinical trial opportunities in Transfusion Medicine: proceedings of a National Heart, Lung, and Blood Institute State-of-the-Science Symposium. Transfus Med Rev. 2010 Oct; 24(4):259-85. Blajchman MA, Glynn SA, Josephson CD, Kleinman SH. PMID: 20851330.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    32. Microarray kit analysis of cytokines in blood product units and segments. Transfusion. 2009 Nov; 49(11):2269-75. Weiskopf RB, Yau R, Sanchez R, Lowell C, Toy P. PMID: 19548981.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    33. Research opportunities for pathogen reduction/inactivation of blood components: summary of an NHLBI workshop. Transfusion. 2009 Jun; 49(6):1262-8. Klein HG, Glynn SA, Ness PM, Blajchman MA. PMID: 19392769.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsPHPublic Health
    34. Cost minimization analysis of preoperative erythropoietin vs autologous and allogeneic blood donation in total joint arthroplasty. J Arthroplasty. 2010 Jan; 25(1):93-6. Green WS, Toy P, Bozic KJ. PMID: 19056224.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    35. Red blood cell age and function. Transfusion. 2008 Sep; 48(9):2026. Weiskopf RB, Feiner J, Toy P. PMID: 18811899.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    36. Computer-generated automatic alerts of respiratory distress after blood transfusion. J Am Med Inform Assoc. 2008 May-Jun; 15(3):383-5. Finlay-Morreale HE, Louie C, Toy P. PMID: 18308991.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    37. Transfusion-related acute lung injury: a case-control pilot study of risk factors. Am J Clin Pathol. 2007 Jul; 128(1):128-34. Sanchez R, Bacchetti P, Toy P. PMID: 17580280.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    38. TRALI--definition, mechanisms, incidence and clinical relevance. Best Pract Res Clin Anaesthesiol. 2007 Jun; 21(2):183-93. Toy P, Lowell C. PMID: 17650771.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    39. Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice. J Exp Med. 2007 Jan 22; 204(1):191-201. Tarbell KV, Petit L, Zuo X, Toy P, Luo X, Mqadmi A, Yang H, Suthanthiran M, Mojsov S, Steinman RM. PMID: 17210729.
      View in: PubMed   Mentions: 136     Fields:    Translation:AnimalsCells
    40. Transfusion-related acute lung injury and transfusion-associated circulatory overload: mutually exclusive or coexisting entities? Transfusion. 2007 Jan; 47(1):171-2. Fiebig EW, Wu AH, Krombach J, Tang J, Nguyen KA, Toy P. PMID: 17207246.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    41. Fresh frozen plasma and platelet transfusion for nonbleeding patients in the intensive care unit: benefit or harm? Crit Care Med. 2006 May; 34(5 Suppl):S170-3. Gajic O, Dzik WH, Toy P. PMID: 16617262.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    42. Fresh blood and aged stored blood are equally efficacious in immediately reversing anemia-induced brain oxygenation deficits in humans. Anesthesiology. 2006 May; 104(5):911-20. Weiskopf RB, Feiner J, Hopf H, Lieberman J, Finlay HE, Quah C, Kramer JH, Bostrom A, Toy P. PMID: 16645441.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    43. Antibodies neutralizing hepsin protease activity do not impact cell growth but inhibit invasion of prostate and ovarian tumor cells in culture. Cancer Res. 2006 Apr 01; 66(7):3611-9. Xuan JA, Schneider D, Toy P, Lin R, Newton A, Zhu Y, Finster S, Vogel D, Mintzer B, Dinter H, Light D, Parry R, Polokoff M, Whitlow M, Wu Q, Parry G. PMID: 16585186.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    44. Designing and testing a computer-based screening system for transfusion-related acute lung injury. Am J Clin Pathol. 2005 Oct; 124(4):601-9. Finlay HE, Cassorla L, Feiner J, Toy P. PMID: 16146824.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansPHPublic Health
    45. Identification of a novel prostate tumor target, mindin/RG-1, for antibody-based radiotherapy of prostate cancer. Cancer Res. 2005 Sep 15; 65(18):8397-405. Parry R, Schneider D, Hudson D, Parkes D, Xuan JA, Newton A, Toy P, Lin R, Harkins R, Alicke B, Biroc S, Kretschmer PJ, Halks-Miller M, Klocker H, Zhu Y, Larsen B, Cobb RR, Bringmann P, Roth G, Lewis JS, Dinter H, Parry G. PMID: 16166318.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    46. Transfusion related acute lung injury: a pediatric perspective. Pediatr Blood Cancer. 2005 Sep; 45(3):248-55. Sanchez R, Toy P. PMID: 15852432.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    47. Extracellular potassium concentrations in red blood cell suspensions after irradiation and washing. Transfusion. 2005 Aug; 45(8):1295-301. Weiskopf RB, Schnapp S, Rouine-Rapp K, Bostrom A, Toy P. PMID: 16078915.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    48. A procedure for rapid issue of red cells for emergency use. Arch Pathol Lab Med. 2005 Apr; 129(4):492-6. Weiskopf RB, Webb M, Stangle D, Klinbergs G, Toy P. PMID: 15794672.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsPHPublic Health
    49. Transfusion-related acute lung injury: definition and review. Crit Care Med. 2005 Apr; 33(4):721-6. Toy P, Popovsky MA, Abraham E, Ambruso DR, Holness LG, Kopko PM, McFarland JG, Nathens AB, Silliman CC, Stroncek D. PMID: 15818095.
      View in: PubMed   Mentions: 119     Fields:    Translation:Humans
    50. Targeting tomoregulin for radioimmunotherapy of prostate cancer. Cancer Res. 2005 Apr 01; 65(7):2846-53. Zhao XY, Schneider D, Biroc SL, Parry R, Alicke B, Toy P, Xuan JA, Sakamoto C, Wada K, Schulze M, Müller-Tiemann B, Parry G, Dinter H. PMID: 15805286.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    51. Acute isovolemic anemia impairs central processing as determined by P300 latency. Clin Neurophysiol. 2005 May; 116(5):1028-32. Weiskopf RB, Toy P, Hopf HW, Feiner J, Finlay HE, Takahashi M, Bostrom A, Songster C, Aminoff MJ. PMID: 15826842.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    52. Transfusion-related acute lung injury. Anesth Analg. 2004 Dec; 99(6):1623-4, table of contents. Toy P, Gajic O. PMID: 15562043.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    53. Recipients of blood from a donor with multiple HLA antibodies: a lookback study of transfusion-related acute lung injury. Transfusion. 2004 Dec; 44(12):1683-8. Toy P, Hollis-Perry KM, Jun J, Nakagawa M. PMID: 15584980.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    54. Acute and transient decrease in neutrophil count in transfusion-related acute lung injury: cases at one hospital. Transfusion. 2004 Dec; 44(12):1689-94. Nakagawa M, Toy P. PMID: 15584981.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    55. Safe lead levels: blood transfusion of extremely low birth weight infants. Clin Pediatr (Phila). 2004 Sep; 43(7):681. Nakagawa M, Dempsey DA, Haller C, Toy P. PMID: 15378161.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    56. CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J Exp Med. 2004 Jun 07; 199(11):1467-77. Tarbell KV, Yamazaki S, Olson K, Toy P, Steinman RM. PMID: 15184500.
      View in: PubMed   Mentions: 216     Fields:    Translation:AnimalsCells
    57. Anthranilate 4H-oxazol-5-ones: novel small molecule antibacterial acyl carrier protein synthase (AcpS) inhibitors. Bioorg Med Chem Lett. 2004 Jan 05; 14(1):37-41. Gilbert AM, Kirisits M, Toy P, Nunn DS, Failli A, Dushin EG, Novikova E, Petersen PJ, Joseph-McCarthy D, McFadyen I, Fritz CC. PMID: 14684293.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    58. Acute isovolemic anemia does not impair peripheral or central nerve conduction. Anesthesiology. 2003 Sep; 99(3):546-51. Weiskopf RB, Aminoff MJ, Hopf HW, Feiner J, Viele MK, Watson JJ, Ho R, Songster C, Toy P. PMID: 12960537.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCellsCTClinical Trials
    59. Heart rate increases linearly in response to acute isovolemic anemia. Transfusion. 2003 Feb; 43(2):235-40. Weiskopf RB, Feiner J, Hopf H, Viele MK, Watson JJ, Lieberman J, Kelley S, Toy P. PMID: 12559019.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    60. Oxygen reverses deficits of cognitive function and memory and increased heart rate induced by acute severe isovolemic anemia. Anesthesiology. 2002 Apr; 96(4):871-7. Weiskopf RB, Feiner J, Hopf HW, Viele MK, Watson JJ, Kramer JH, Ho R, Toy P. PMID: 11964594.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCTClinical Trials
    61. Cloning and genetic characterization of an evolutionarily conserved human olfactory receptor that is differentially expressed across species. Gene. 2001 Oct 31; 278(1-2):41-51. Yuan TT, Toy P, McClary JA, Lin RJ, Miyamoto NG, Kretschmer PJ. PMID: 11707321.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    62. Research opportunities in transfusion medicine. JAMA. 2001 Feb 07; 285(5):577-80. Silberstein LE, Toy P. PMID: 11176862.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    63. Subcutaneous perfusion and oxygen during acute severe isovolemic hemodilution in healthy volunteers. Arch Surg. 2000 Dec; 135(12):1443-9. Hopf HW, Viele M, Watson JJ, Feiner J, Weiskopf R, Hunt TK, Noorani M, Yeap H, Ho R, Toy P. PMID: 11115350.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    64. Electrocardiographic ST-segment changes during acute, severe isovolemic hemodilution in humans. Anesthesiology. 2000 Oct; 93(4):1004-10. Leung JM, Weiskopf RB, Feiner J, Hopf HW, Kelley S, Viele M, Lieberman J, Watson J, Noorani M, Pastor D, Yeap H, Ho R, Toy P. PMID: 11020755.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    65. Universal WBC reduction. Transfusion. 2000 Jun; 40(6):751-2. Thurer RL, Luban NL, AuBuchon JP, Silver H, McCarthy LJ, Dzik S, Stowell CP, Moore SB, Vamvakas EC, Armstrong W, Kanter MH, Jeter E, Becker J, Higgins M, Galel S, Kleinman S, Marshall CS, Newman R, Ocaríz JA, Blackall D, Petz LD, Toy P, Oberman H, Siegel DL, Price TH, Slichter SJ. PMID: 10864999.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCellsPHPublic Health
    66. Very severe outcomes associated with autologous blood donation. Transfusion. 1996 Aug; 36(8):761. McVay PA, Toy PT. PMID: 8780675.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    67. Audit and education in transfusion medicine. Vox Sang. 1996; 70(1):1-5. Toy PT. PMID: 8928483.
      View in: PubMed   Mentions: 1     Fields:    
    68. Physician recommendation as the key factor in patients' decisions to participate in preoperative autologous blood donation programs: Preoperative Autologous Blood Donation Study Group. Am J Surg. 1994 Jul; 168(1):2-5. Ferguson KJ, Strauss RG, Toy PT. PMID: 8024094.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    69. Effectiveness of transfusion audits and practice guidelines. Arch Pathol Lab Med. 1994 Apr; 118(4):435-7. Toy PT. PMID: 8166594.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    70. Continuous quality improvement. Autologous blood donations. Arch Pathol Lab Med. 1992 Jun; 116(6):611-2. Toy PT. PMID: 1616420.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    71. Factors associated with successful autologous blood donation for elective surgery. Am J Clin Pathol. 1992 Mar; 97(3):304-8. McVay PA, Hoag MS, Lee SJ, Toy PT. PMID: 1543153.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    72. Laboratory hemostatic abnormalities in massively transfused patients given red blood cells and crystalloid. Am J Clin Pathol. 1991 Dec; 96(6):770-3. Leslie SD, Toy PT. PMID: 1746495.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    73. Probable reasons that autologous blood was not donated by patients having surgery for which crossmatched blood was ordered. Transfusion. 1991 Nov-Dec; 31(9):810-3. McVay PA, Strauss RG, Stehling LC, Toy PT. PMID: 1755085.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    74. Donor room personnel attitudes toward autologous donors. Transfusion. 1991 Mar-Apr; 31(3):249-53. Skettino S, Ferguson K, Andrews A, Stehling LC, Strauss RG, Toy PT. PMID: 2003325.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    75. Return of autologous blood donors as homologous blood donors. Transfusion. 1991 Feb; 31(2):119-21. McVay PA, Fung HC, Toy PT. PMID: 1996480.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    76. Lack of increased bleeding after paracentesis and thoracentesis in patients with mild coagulation abnormalities. Transfusion. 1991 Feb; 31(2):164-71. McVay PA, Toy PT. PMID: 1996485.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    77. The variability of transfusion practice in coronary artery bypass surgery. Transfusion Medicine Academic Award Group. JAMA. 1991 Jan 02; 265(1):86-90. Goodnough LT, Johnston MF, Toy PT. PMID: 1984129.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    78. Lack of increased bleeding after liver biopsy in patients with mild hemostatic abnormalities. Am J Clin Pathol. 1990 Dec; 94(6):747-53. McVay PA, Toy PT. PMID: 2123077.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    79. Donation reactions among autologous donors. Transfusion. 1990 Mar-Apr; 30(3):249-52. McVay PA, Andrews A, Kaplan EB, Black DB, Stehling LC, Strauss RG, Toy PT. PMID: 2315998.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    80. Moderate and severe reactions during autologous blood donations are no more frequent than during homologous blood donations. Vox Sang. 1990; 59(2):70-2. McVay PA, Andrews A, Hoag MS, Polan D, Skettino S, Stehling LC, Strauss RG, Toy PT. PMID: 2238567.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    81. Safety and use of autologous blood donation during the third trimester of pregnancy. Am J Obstet Gynecol. 1989 Jun; 160(6):1479-86; discussion 1486-8. McVay PA, Hoag RW, Hoag MS, Toy PT. PMID: 2735369.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    82. Oxygen-induced marrow red cell hypoplasia leading to transfusion in sickle painful crisis. Am J Hematol. 1988 Jan; 27(1):67-8. Lane PK, Embury SH, Toy PT. PMID: 3128106.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    83. Elimination of 37 degrees C reading: reduction of workload in a transfusion service. Transfusion. 1984 Nov-Dec; 24(6):542-3. Purcelli J, Reid ME, Burns MA, Toy PT. PMID: 6506192.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    84. Use of preserved autologous red blood cells to absorb warm autoantibodies from the serum of patients receiving blood transfusion therapy. Vox Sang. 1984; 46(6):355-9. Reid ME, Toy PT. PMID: 6464409.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    85. Intravenous dimethylsulfoxide therapy causes severe hemolysis mimicking a hemolytic transfusion reaction. Transfusion. 1983 Sep-Oct; 23(5):405. Samoszuk M, Reid ME, Toy PT. PMID: 6623613.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    86. Simplified method for recovery of autologous red blood cells from transfused patients. Am J Clin Pathol. 1983 Mar; 79(3):364-6. Reid ME, Toy PT. PMID: 6829505.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    Pearl's Networks
    Concepts (382)
    Derived automatically from this person's publications.
    _
    Co-Authors (37)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _