Maxence Nachury, PhD

Title(s)Professor, Ophthalmology
SchoolSchool of Medicine
Address555 Mission Bay Blvd South, #352X
San Francisco CA 94158
ORCID ORCID Icon0000-0003-4918-1562 Additional info
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    Collapse Biography 
    Collapse Education and Training
    UC Berkeley, BerkeleyPhD12/2001Molecular and Cellular Biology
    Stanford and Genentech, Stanford and South San FranciscoPostodoctorate12/2007Cell Biology and Biochemistry
    University of California, San Francisco, CA2018Diversity, Equity, and Inclusion Champion Training
    Collapse Awards and Honors
    Kinship Foundation2010Searle Scholar
    American Society for Cell Biology2011Early Career Life Scientist Award
    American Society for Cell Biology2016Keith R. Porter Fellowship Award
    Association for Research in Vision and Ophthalmology2019Cogan Award

    Collapse Overview 
    Collapse Overview
    We study the primary cilium, a surface-exposed organelle required for vision, olfaction and developmental signaling. Our lab is interested in the mechanisms of trafficking in and out of cilia and how trafficking decisions impact signaling at the cilium. One research axis focuses on Bardet-Biedl Syndrome (BBS), a ciliopathy characterized by obesity, skeletal malformations and kidney cysts. The BBSome is an evolutionarily conserved complex of 8 BBS proteins that traffics signaling receptors out of cilia and we aim to decipher the molecular details of BBSome-mediated trafficking and the cellular, biochemical and structural level. A second research direction is aimed at cilia-derived extracellular vesicles (EVs). Ciliary signaling receptors that fail conventional exit are packaged into ciliary EVs. By dissecting the mechanisms of ciliary EV biogenesis, we will gain insight into the roles of these extracellular parcels in cell-cell communication.

    Collapse Research 
    Collapse Research Activities and Funding
    Structural basis of BBSome-mediated ciliary exit
    NIH R01EY031462Jun 1, 2020 - May 31, 2024
    Role: Principal Investigator
    Proteomics of Primary Cilia through Proximity Labeling
    NIH R21HD087126Dec 1, 2015 - Nov 30, 2019
    Role: Principal Investigator
    Quality control of the primary cilium proteome
    NIH R01GM089933Apr 1, 2010 - Jan 31, 2024
    Role: Principal Investigator

    Collapse ORNG Applications 
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. 352-OR: Regulation of Melanocortin Receptor 4 (MC4R) Ciliary Trafficking. Diabetes. 2023 Jun 20; 72(Supplement_1). NACHURY NM. .
      View in: Publisher Site   Mentions:
    2. The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia. Dev Cell. 2023 04 24; 58(8):677-693.e9. Shinde SR, Mick DU, Aoki E, Rodrigues RB, Gygi SP, Nachury MV. PMID: 37019113; PMCID: PMC10133032.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    3. MRAP2 regulates energy homeostasis by promoting primary cilia localization of MC4R. JCI Insight. 2023 Jan 24; 8(2). Bernard A, Ojeda Naharros I, Yue X, Mifsud F, Blake A, Bourgain-Guglielmetti F, Ciprin J, Zhang S, McDaid E, Kim K, Nachury MV, Reiter JF, Vaisse C. PMID: 36692018; PMCID: PMC9977312.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    4. The gymnastics of intraflagellar transport complexes keeps trains running inside cilia. Cell. 2022 12 22; 185(26):4863-4865. Nachury MV. PMID: 36563659.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    5. Comparative Risk of Incident Cancer in Patients with Inflammatory Bowel Disease with Prior Non-digestive Malignancy According to Immunomodulator: a Multicentre Cohort Study. J Crohns Colitis. 2022 Nov 01; 16(10):1523-1530. Poullenot F, Amiot A, Nachury M, Viennot S, Altwegg R, Bouhnik Y, Abitbol V, Nancey S, Vuitton L, Peyrin-Biroulet L, Biron A, Fumery M, Picon L, Vidon M, Reenaers C, Serrero M, Savoye G, Beaugerie L, Rivière P, Laharie D. PMID: 35512337.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    6. Shedding of ciliary vesicles at a glance. J Cell Sci. 2022 10 01; 135(19). Ojeda Naharros I, Nachury MV. PMID: 36222105; PMCID: PMC10399986.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    7. Localization of GFP-Tagged Proteins Under the Electron Microscope. . 2021 Jul 27; 169:201-212. Gil-Perotin GS, Cebrián-Silla CA, Herranz-Pérez HV, García-Belda GP, Gil-García GS, Fil FM, Lee LJ, Nachury NM, García-Verdugo GJ. .
      View in: Publisher Site   Mentions:
    8. Time-resolved proteomics profiling of the ciliary Hedgehog response. J Cell Biol. 2021 05 03; 220(5). May EA, Kalocsay M, D'Auriac IG, Schuster PS, Gygi SP, Nachury MV, Mick DU. PMID: 33856408; PMCID: PMC8054476.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    9. Ubiquitin chains earmark GPCRs for BBSome-mediated removal from cilia. J Cell Biol. 2020 12 07; 219(12). Shinde SR, Nager AR, Nachury MV. PMID: 33185668; PMCID: PMC7716378.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    10. Near-atomic structures of the BBSome reveal the basis for BBSome activation and binding to GPCR cargoes. Elife. 2020 06 08; 9. Yang S, Bahl K, Chou HT, Woodsmith J, Stelzl U, Walz T, Nachury MV. PMID: 32510327; PMCID: PMC7311171.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    11. The Molecular Architecture of Native BBSome Obtained by an Integrated Structural Approach. Structure. 2019 09 03; 27(9):1384-1394.e4. Chou HT, Apelt L, Farrell DP, White SR, Woodsmith J, Svetlov V, Goldstein JS, Nager AR, Li Z, Muller J, Dollfus H, Nudler E, Stelzl U, DiMaio F, Nachury MV, Walz T. PMID: 31303482; PMCID: PMC6726506.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    12. Establishing and regulating the composition of cilia for signal transduction. Nat Rev Mol Cell Biol. 2019 07; 20(7):389-405. Nachury MV, Mick DU. PMID: 30948801; PMCID: PMC6738346.
      View in: PubMed   Mentions: 150     Fields:    Translation:HumansAnimalsCells
    13. Effects of α-tubulin acetylation on microtubule structure and stability. Proc Natl Acad Sci U S A. 2019 05 21; 116(21):10366-10371. Eshun-Wilson L, Zhang R, Portran D, Nachury MV, Toso DB, Löhr T, Vendruscolo M, Bonomi M, Fraser JS, Nogales E. PMID: 31072936; PMCID: PMC6535015.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    14. The molecular machines that traffic signaling receptors into and out of cilia. Curr Opin Cell Biol. 2018 04; 51:124-131. Nachury MV. PMID: 29579578; PMCID: PMC5949257.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansCells
    15. BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone. J Cell Biol. 2018 05 07; 217(5):1847-1868. Ye F, Nager AR, Nachury MV. PMID: 29483145; PMCID: PMC5940304.
      View in: PubMed   Mentions: 112     Fields:    Translation:AnimalsCells
    16. A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies. Nat Genet. 2018 03; 50(3):460-471. Breslow DK, Hoogendoorn S, Kopp AR, Morgens DW, Vu BK, Kennedy MC, Han K, Li A, Hess GT, Bassik MC, Chen JK, Nachury MV. PMID: 29459677; PMCID: PMC5862771.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    17. BORC Regulates the Axonal Transport of Synaptic Vesicle Precursors by Activating ARL-8. Curr Biol. 2017 Sep 11; 27(17):2569-2578.e4. Niwa S, Tao L, Lu SY, Liew GM, Feng W, Nachury MV, Shen K. PMID: 28823680; PMCID: PMC5693321.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    18. Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action. Elife. 2017 05 19; 6. Steinman JB, Santarossa CC, Miller RM, Yu LS, Serpinskaya AS, Furukawa H, Morimoto S, Tanaka Y, Nishitani M, Asano M, Zalyte R, Ondrus AE, Johnson AG, Ye F, Nachury MV, Fukase Y, Aso K, Foley MA, Gelfand VI, Chen JK, Carter AP, Kapoor TM. PMID: 28524820; PMCID: PMC5478271.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    19. Microtubules acquire resistance from mechanical breakage through intralumenal acetylation. Science. 2017 04 21; 356(6335):328-332. Xu Z, Schaedel L, Portran D, Aguilar A, Gaillard J, Marinkovich MP, Théry M, Nachury MV. PMID: 28428427; PMCID: PMC5457157.
      View in: PubMed   Mentions: 179     Fields:    Translation:HumansCells
    20. Membrane traffic control by cytoskeletal and molecular machines. Mol Biol Cell. 2017 03 15; 28(6):697-698. Lee TH, Nachury MV. PMID: 28292910; PMCID: PMC5349772.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    21. Fifteen years of research on oral-facial-digital syndromes: from 1 to 16 causal genes. J Med Genet. 2017 06; 54(6):371-380. Bruel AL, Franco B, Duffourd Y, Thevenon J, Jego L, Lopez E, Deleuze JF, Doummar D, Giles RH, Johnson CA, Huynen MA, Chevrier V, Burglen L, Morleo M, Desguerres I, Pierquin G, Doray B, Gilbert-Dussardier B, Reversade B, Steichen-Gersdorf E, Baumann C, Panigrahi I, Fargeot-Espaliat A, Dieux A, David A, Goldenberg A, Bongers E, Gaillard D, Argente J, Aral B, Gigot N, St-Onge J, Birnbaum D, Phadke SR, Cormier-Daire V, Eguether T, Pazour GJ, Herranz-Pérez V, Goldstein JS, Pasquier L, Loget P, Saunier S, Mégarbané A, Rosnet O, Leroux MR, Wallingford JB, Blacque OE, Nachury MV, Attie-Bitach T, Rivière JB, Faivre L, Thauvin-Robinet C. PMID: 28289185; PMCID: PMC5557276.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    22. Measurement of tubulin oligomers self-assembly by FRET. Protocol Exchange. 2017 Mar 9. Portran PD, Portran PD, Nachury NM. .
      View in: Publisher Site   Mentions:
    23. Tubulin acetylation protects long-lived microtubules against mechanical ageing. Nat Cell Biol. 2017 04; 19(4):391-398. Portran D, Schaedel L, Xu Z, Théry M, Nachury MV. PMID: 28250419; PMCID: PMC5376231.
      View in: PubMed   Mentions: 187     Fields:    Translation:AnimalsCells
    24. An Actin Network Dispatches Ciliary GPCRs into Extracellular Vesicles to Modulate Signaling. Cell. 2017 Jan 12; 168(1-2):252-263.e14. Nager AR, Goldstein JS, Herranz-Pérez V, Portran D, Ye F, Garcia-Verdugo JM, Nachury MV. PMID: 28017328; PMCID: PMC5235987.
      View in: PubMed   Mentions: 161     Fields:    Translation:HumansAnimalsCells
    25. Localization of GFP-Tagged Proteins at the Electron Microscope. Receptor and Ion Channel Detection in the Brain. 2016 Jan 1; 110:179-190. Gil-Perotin GS, Cebrián-Silla CA, Herranz-Pérez HV, García-Belda GP, Gil-García GS, Fil FM, Lee LJ, Nachury NM, García-Verdugo GJ. .
      View in: Publisher Site   Mentions:
    26. Abstract B068: Structural basis for Notch1 engagement of Delta-like 4 and Jagged1. Immune Regulation of T Cell Responses/ Evolving Concepts in Cancer Immunology. 2016 Jan 1; b068-b068. Luca LV, Jude JK, Pierce PN, Nachury NM, Fischer FS, Garcia GK. .
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    27. Loss of the BBSome perturbs endocytic trafficking and disrupts virulence of Trypanosoma brucei. Proc Natl Acad Sci U S A. 2016 Jan 19; 113(3):632-7. Langousis G, Shimogawa MM, Saada EA, Vashisht AA, Spreafico R, Nager AR, Barshop WD, Nachury MV, Wohlschlegel JA, Hill KL. PMID: 26721397; PMCID: PMC4725476.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    28. The Intraflagellar Transport Protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3. Cilia. 2015 Dec 1; 4(Suppl 1):o18. Liew LG, Ye YF, Nager NA, Murphy MJ, Lee LJ, Aguiar AM, Breslow BD, Gygi GS, Nachury NM. .
      View in: Publisher Site   Mentions:
    29. Proteomics of Primary Cilia by Proximity Labeling. Dev Cell. 2015 Nov 23; 35(4):497-512. Mick DU, Rodrigues RB, Leib RD, Adams CM, Chien AS, Gygi SP, Nachury MV. PMID: 26585297; PMCID: PMC4662609.
      View in: PubMed   Mentions: 183     Fields:    Translation:AnimalsCells
    30. Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity. ACS Chem Biol. 2016 Jan 15; 11(1):53-60. See SK, Hoogendoorn S, Chung AH, Ye F, Steinman JB, Sakata-Kato T, Miller RM, Cupido T, Zalyte R, Carter AP, Nachury MV, Kapoor TM, Chen JK. PMID: 26555042; PMCID: PMC4715766.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    31. Microtubules self-repair in response to mechanical stress. Nat Mater. 2015 Nov; 14(11):1156-63. Schaedel L, John K, Gaillard J, Nachury MV, Blanchoin L, Théry M. PMID: 26343914; PMCID: PMC4620915.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansAnimalsCells
    32. Structural biology. Structural basis for Notch1 engagement of Delta-like 4. Science. 2015 Feb 20; 347(6224):847-53. Luca VC, Jude KM, Pierce NW, Nachury MV, Fischer S, Garcia KC. PMID: 25700513; PMCID: PMC4445638.
      View in: PubMed   Mentions: 121     Fields:    Translation:AnimalsCells
    33. Analysis of soluble protein entry into primary cilia using semipermeabilized cells. Methods Cell Biol. 2015; 127:203-21. Breslow DK, Nachury MV. PMID: 25837393; PMCID: PMC4797650.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    34. Structural basis for membrane targeting of the BBSome by ARL6. Nat Struct Mol Biol. 2014 Dec; 21(12):1035-41. Mourão A, Nager AR, Nachury MV, Lorentzen E. PMID: 25402481; PMCID: PMC4255524.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    35. The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3. Dev Cell. 2014 Nov 10; 31(3):265-278. Liew GM, Ye F, Nager AR, Murphy JP, Lee JS, Aguiar M, Breslow DK, Gygi SP, Nachury MV. PMID: 25443296; PMCID: PMC4255629.
      View in: PubMed   Mentions: 117     Fields:    Translation:AnimalsCells
    36. How do cilia organize signalling cascades? Philos Trans R Soc Lond B Biol Sci. 2014 Sep 05; 369(1650). Nachury MV. PMID: 25047619; PMCID: PMC4113109.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    37. The oral-facial-digital syndrome gene C2CD3 encodes a positive regulator of centriole elongation. Nat Genet. 2014 Aug; 46(8):905-11. Thauvin-Robinet C, Lee JS, Lopez E, Herranz-Pérez V, Shida T, Franco B, Jego L, Ye F, Pasquier L, Loget P, Gigot N, Aral B, Lopes CA, St-Onge J, Bruel AL, Thevenon J, González-Granero S, Alby C, Munnich A, Vekemans M, Huet F, Fry AM, Saunier S, Rivière JB, Attié-Bitach T, Garcia-Verdugo JM, Faivre L, Mégarbané A, Nachury MV. PMID: 24997988; PMCID: PMC4120243.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    38. Α-tubulin K40 acetylation is required for contact inhibition of proliferation and cell-substrate adhesion. Mol Biol Cell. 2014 Jun 15; 25(12):1854-66. Aguilar A, Becker L, Tedeschi T, Heller S, Iomini C, Nachury MV. PMID: 24743598; PMCID: PMC4055265.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    39. Movement of Signaling Receptors Inside Primary Cilia. Biophysical Journal. 2014 Jan 1; 106(2):9a. Nachury NM. .
      View in: Publisher Site   Mentions:
    40. Effects of tubulin acetylation and tubulin acetyltransferase binding on microtubule structure. Mol Biol Cell. 2014 Jan; 25(2):257-66. Howes SC, Alushin GM, Shida T, Nachury MV, Nogales E. PMID: 24227885; PMCID: PMC3890346.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    41. Cilia grow by taking a bite out of the cell. Dev Cell. 2013 Oct 28; 27(2):126-127. Pierce NW, Nachury MV. PMID: 24176638; PMCID: PMC3890250.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    42. An in vitro assay for entry into cilia reveals unique properties of the soluble diffusion barrier. J Cell Biol. 2013 Oct 14; 203(1):129-47. Breslow DK, Koslover EF, Seydel F, Spakowitz AJ, Nachury MV. PMID: 24100294; PMCID: PMC3798247.
      View in: PubMed   Mentions: 106     Fields:    Translation:AnimalsCells
    43. αTAT1 catalyses microtubule acetylation at clathrin-coated pits. Nature. 2013 Oct 24; 502(7472):567-70. Montagnac G, Meas-Yedid V, Irondelle M, Castro-Castro A, Franco M, Shida T, Nachury MV, Benmerah A, Olivo-Marin JC, Chavrier P. PMID: 24097348; PMCID: PMC3970258.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    44. Exome sequencing of Bardet-Biedl syndrome patient identifies a null mutation in the BBSome subunit BBIP1 (BBS18). J Med Genet. 2014 Feb; 51(2):132-6. Scheidecker S, Etard C, Pierce NW, Geoffroy V, Schaefer E, Muller J, Chennen K, Flori E, Pelletier V, Poch O, Marion V, Stoetzel C, Strähle U, Nachury MV, Dollfus H. PMID: 24026985; PMCID: PMC3966300.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    45. Single molecule imaging reveals a major role for diffusion in the exploration of ciliary space by signaling receptors. Elife. 2013 Aug 06; 2:e00654. Ye F, Breslow DK, Koslover EF, Spakowitz AJ, Nelson WJ, Nachury MV. PMID: 23930224; PMCID: PMC3736543.
      View in: PubMed   Mentions: 74     Fields:    Translation:Cells
    46. Structure of the α-tubulin acetyltransferase, αTAT1, and implications for tubulin-specific acetylation. Proc Natl Acad Sci U S A. 2012 Nov 27; 109(48):19655-60. Friedmann DR, Aguilar A, Fan J, Nachury MV, Marmorstein R. PMID: 23071314; PMCID: PMC3511727.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    47. A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened. PLoS Genet. 2011 Nov; 7(11):e1002358. Seo S, Zhang Q, Bugge K, Breslow DK, Searby CC, Nachury MV, Sheffield VC. PMID: 22072986; PMCID: PMC3207910.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansAnimalsCells
    48. Give chance a chance. Mol Biol Cell. 2011 Nov; 22(21):3919-20. Nachury MV. PMID: 22039061; PMCID: PMC3204048.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    49. Primary cilia: how to keep the riff-raff in the plasma membrane. Curr Biol. 2011 Jun 07; 21(11):R434-6. Breslow DK, Nachury MV. PMID: 21640903.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    50. Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome. Proc Natl Acad Sci U S A. 2011 Feb 15; 108(7):2759-64. Westlake CJ, Baye LM, Nachury MV, Wright KJ, Ervin KE, Phu L, Chalouni C, Beck JS, Kirkpatrick DS, Slusarski DC, Sheffield VC, Scheller RH, Jackson PK. PMID: 21273506; PMCID: PMC3041065.
      View in: PubMed   Mentions: 246     Fields:    Translation:HumansAnimalsCells
    51. The major alpha-tubulin K40 acetyltransferase alphaTAT1 promotes rapid ciliogenesis and efficient mechanosensation. Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50):21517-22. Shida T, Cueva JG, Xu Z, Goodman MB, Nachury MV. PMID: 21068373; PMCID: PMC3003046.
      View in: PubMed   Mentions: 215     Fields:    Translation:AnimalsCells
    52. Maxence Nachury: a transporting view of the primary cilium. Interview by Ben Short. J Cell Biol. 2010 Nov 01; 191(3):436-7. Nachury M. PMID: 21041439; PMCID: PMC3003325.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    53. The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia. Cell. 2010 Jun 25; 141(7):1208-19. Jin H, White SR, Shida T, Schulz S, Aguiar M, Gygi SP, Bazan JF, Nachury MV. PMID: 20603001; PMCID: PMC2898735.
      View in: PubMed   Mentions: 351     Fields:    Translation:HumansAnimalsCells
    54. A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution. Science. 2010 Jul 23; 329(5990):436-9. Hu Q, Milenkovic L, Jin H, Scott MP, Nachury MV, Spiliotis ET, Nelson WJ. PMID: 20558667; PMCID: PMC3092790.
      View in: PubMed   Mentions: 270     Fields:    Translation:AnimalsCells
    55. The perennial organelle: assembly and disassembly of the primary cilium. J Cell Sci. 2010 Feb 15; 123(Pt 4):511-8. Seeley ES, Nachury MV. PMID: 20144999; PMCID: PMC2818191.
      View in: PubMed   Mentions: 114     Fields:    Translation:HumansAnimalsCells
    56. Trafficking to the ciliary membrane: how to get across the periciliary diffusion barrier? Annu Rev Cell Dev Biol. 2010; 26:59-87. Nachury MV, Seeley ES, Jin H. PMID: 19575670; PMCID: PMC2952038.
      View in: PubMed   Mentions: 249     Fields:    Translation:HumansAnimalsCells
    57. Constructing and deconstructing roles for the primary cilium in tissue architecture and cancer. Methods Cell Biol. 2009; 94:299-313. Seeley ES, Nachury MV. PMID: 20362097; PMCID: PMC2885964.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    58. The BBSome. Curr Biol. 2009 Jun 23; 19(12):R472-3. Jin H, Nachury MV. PMID: 19549489.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    59. A BBSome subunit links ciliogenesis, microtubule stability, and acetylation. Dev Cell. 2008 Dec; 15(6):854-65. Loktev AV, Zhang Q, Beck JS, Searby CC, Scheetz TE, Bazan JF, Slusarski DC, Sheffield VC, Jackson PK, Nachury MV. PMID: 19081074.
      View in: PubMed   Mentions: 160     Fields:    Translation:AnimalsCells
    60. How to build a signalling organelle: A molecular pathway for biogenesis of the ciliary membrane. The FASEB Journal. 2008 Mar 1; 22:628.1-628.1. Nachury NM. .
      View in: Publisher Site   Mentions:
    61. The nucleolar phosphatase Cdc14B is dispensable for chromosome segregation and mitotic exit in human cells. Cell Cycle. 2008 May 01; 7(9):1184-90. Berdougo E, Nachury MV, Jackson PK, Jallepalli PV. PMID: 18418058.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    62. Tandem affinity purification of the BBSome, a critical regulator of Rab8 in ciliogenesis. Methods Enzymol. 2008; 439:501-13. Nachury MV. PMID: 18374185.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    63. The END network couples spindle pole assembly to inhibition of the anaphase-promoting complex/cyclosome in early mitosis. Dev Cell. 2007 Jul; 13(1):29-42. Ban KH, Torres JZ, Miller JJ, Mikhailov A, Nachury MV, Tung JJ, Rieder CL, Jackson PK. PMID: 17609108.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    64. A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. Cell. 2007 Jun 15; 129(6):1201-13. Nachury MV, Loktev AV, Zhang Q, Westlake CJ, Peränen J, Merdes A, Slusarski DC, Scheller RH, Bazan JF, Sheffield VC, Jackson PK. PMID: 17574030.
      View in: PubMed   Mentions: 771     Fields:    Translation:HumansAnimalsCells
    65. Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor. Genes Dev. 2006 Sep 01; 20(17):2410-20. Miller JJ, Summers MK, Hansen DV, Nachury MV, Lehman NL, Loktev A, Jackson PK. PMID: 16921029; PMCID: PMC1560415.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansCells
    66. A Rae1-containing ribonucleoprotein complex is required for mitotic spindle assembly. Cell. 2005 Apr 22; 121(2):223-34. Blower MD, Nachury M, Heald R, Weis K. PMID: 15851029.
      View in: PubMed   Mentions: 143     Fields:    Translation:HumansAnimalsCells
    67. Xenopus Cdc14 alpha/beta are localized to the nucleolus and centrosome and are required for embryonic cell division. BMC Cell Biol. 2004 Jul 13; 5:27. Kaiser BK, Nachury MV, Gardner BE, Jackson PK. PMID: 15251038; PMCID: PMC481057.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    68. Importin beta is a mitotic target of the small GTPase Ran in spindle assembly. Cell. 2001 Jan 12; 104(1):95-106. Nachury MV, Maresca TJ, Salmon WC, Waterman-Storer CM, Heald R, Weis K. PMID: 11163243.
      View in: PubMed   Mentions: 161     Fields:    Translation:AnimalsCells
    69. The direction of transport through the nuclear pore can be inverted. Proc Natl Acad Sci U S A. 1999 Aug 17; 96(17):9622-7. Nachury MV, Weis K. PMID: 10449743; PMCID: PMC22259.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    70. Cloning and characterization of hSRP1 gamma, a tissue-specific nuclear transport factor. Proc Natl Acad Sci U S A. 1998 Jan 20; 95(2):582-7. Nachury MV, Ryder UW, Lamond AI, Weis K. PMID: 9435235; PMCID: PMC18463.
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