Michael Metrick, MD, PhD

Title(s)RESIDENT, Pathology
SchoolSchool of Medicine
Address513 Parnassus Avenue, HSW, #527
San Francisco CA 94143
PronounsHe/Him/His
ORCID ORCID Icon0000-0002-9998-4630 Additional info
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    James Madison University, Harrisonburg, VABS05/2013Chemistry
    University of Illinois at Chicago, Chicago, ILMD05/2024Medicine
    University of Cambridge, Cambridge, UKPhD10/2021Chemistry

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Secondary Processes Dominate the Quiescent, Spontaneous Aggregation of α-Synuclein at Physiological pH with Sodium Salts. ACS Chem Neurosci. 2023 09 06; 14(17):3125-3131. Horne RI, Metrick MA, Man W, Rinauro DJ, Brotzakis ZF, Chia S, Meisl G, Vendruscolo M. PMID: 37578897; PMCID: PMC10485892.
      View in: PubMed   Mentions: 6     Fields:    
    2. Case report of a patient with unclassified tauopathy with molecular and neuropathological features of both progressive supranuclear palsy and corticobasal degeneration. Acta Neuropathol Commun. 2023 06 01; 11(1):88. Koga S, Metrick MA, Golbe LI, Santambrogio A, Kim M, Soto-Beasley AI, Walton RL, Baker MC, De Castro CF, DeTure M, Russell D, Navia BA, Sandiego C, Ross OA, Vendruscolo M, Caughey B, Dickson DW. PMID: 37264457; PMCID: PMC10236843.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    3. Computational maturation of a single-domain antibody against Aβ42 aggregation. Chem Sci. 2021 Oct 27; 12(41):13940-13948. Lin J, Figazzolo C, Metrick MA, Sormanni P, Vendruscolo M. PMID: 35475123; PMCID: PMC8901120.
      View in: PubMed   Mentions: 1  
    4. Detection of chronic wasting disease in mule and white-tailed deer by RT-QuIC analysis of outer ear. Sci Rep. 2021 04 08; 11(1):7702. Ferreira NC, Charco JM, Plagenz J, Orru CD, Denkers ND, Metrick MA, Hughson AG, Griffin KA, Race B, Hoover EA, Castilla J, Nichols TA, Miller MW, Caughey B. PMID: 33833330; PMCID: PMC8032746.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    5. A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases. Acta Neuropathol Commun. 2020 02 22; 8(1):22. Metrick MA, Ferreira NDC, Saijo E, Kraus A, Newell K, Zanusso G, Vendruscolo M, Ghetti B, Caughey B. PMID: 32087764; PMCID: PMC7036215.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    6. Correction to: 4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration. Acta Neuropathol. 2020 Jan; 139(1):79-81. Saijo E, Metrick MA, Koga S, Parchi P, Litvan I, Spina S, Boxer A, Rojas JC, Galasko D, Kraus A, Rossi M, Newell K, Zanusso G, Grinberg LT, Seeley WW, Ghetti B, Dickson DW, Caughey B. PMID: 31748840; PMCID: PMC7193369.
      View in: PubMed   Mentions: 2     Fields:    
    7. Million-fold sensitivity enhancement in proteopathic seed amplification assays for biospecimens by Hofmeister ion comparisons. Proc Natl Acad Sci U S A. 2019 11 12; 116(46):23029-23039. Metrick MA, do Carmo Ferreira N, Saijo E, Hughson AG, Kraus A, Orrú C, Miller MW, Zanusso G, Ghetti B, Vendruscolo M, Caughey B. PMID: 31641070; PMCID: PMC6859373.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    8. 4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration. Acta Neuropathol. 2020 01; 139(1):63-77. Saijo E, Metrick MA, Koga S, Parchi P, Litvan I, Spina S, Boxer A, Rojas JC, Galasko D, Kraus A, Rossi M, Newell K, Zanusso G, Grinberg LT, Seeley WW, Ghetti B, Dickson DW, Caughey B. PMID: 31616982; PMCID: PMC7192393.
      View in: PubMed   Mentions: 71     Fields:    Translation:Humans
    9. Ultrasensitive RT-QuIC Seed Amplification Assays for Disease-Associated Tau, α-Synuclein, and Prion Aggregates. Methods Mol Biol. 2019; 1873:19-37. Saijo E, Groveman BR, Kraus A, Metrick M, Orrù CD, Hughson AG, Caughey B. PMID: 30341601.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    10. Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease. Acta Neuropathol. 2019 04; 137(4):585-598. Kraus A, Saijo E, Metrick MA, Newell K, Sigurdson CJ, Zanusso G, Ghetti B, Caughey B. PMID: 30570675; PMCID: PMC6426988.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimals
    11. Hofmeister Ion-Induced Changes in Water Structure Correlate with Changes in Solvation of an Aggregated Protein Complex. Langmuir. 2016 Feb 09; 32(5):1360-9. Light TP, Corbett KM, Metrick MA, MacDonald G. PMID: 26760222.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    12. Variable-Field Analytical Ultracentrifugation: I. Time-Optimized Sedimentation Equilibrium. Biophys J. 2015 Aug 18; 109(4):827-37. Ma J, Metrick M, Ghirlando R, Zhao H, Schuck P. PMID: 26287634; PMCID: PMC4547334.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    13. Hofmeister ion effects on the solvation and thermal stability of model proteins lysozyme and myoglobin. Colloids and Surfaces A. 2015; 20:242-251. Michael Metrick Gina MacDonald. . View Publication.
    14. The effects of buffers and pH on the thermal stability, unfolding and substrate binding of RecA. Biophys Chem. 2013 Dec 31; 184:29-36. Metrick MA, Temple JE, MacDonald G. PMID: 24036048.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
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