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PubMed Mentions:
1 Fields:
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Expanding the Prion Paradigm to Include Alzheimer and Parkinson Diseases. JAMA Neurol. 2024 Oct 01; 81(10):1023-1024.
Condello C, Westaway D, Prusiner SB. PMID: 39158847.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Cryo-EM structures reveal tau filaments from Down syndrome adopt Alzheimer's disease fold. Acta Neuropathol Commun. 2024 06 12; 12(1):94.
Ghosh U, Tse E, Yang H, Shi M, Caro CD, Wang F, Merz GE, Prusiner SB, Southworth DR, Condello C. PMID: 38867338; PMCID: PMC11167798.
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HumansCells
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Cryo-EM Structures Reveal Tau Filaments from Down Syndrome Adopt Alzheimer's Disease Fold. bioRxiv. 2024 May 28.
Ghosh U, Tse E, Yang H, Shi M, Carlo CD, Wang F, Merz GE, Prusiner SB, Southworth DR, Condello C. PMID: 38617229; PMCID: PMC11014571.
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PubMed Mentions:
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Viroids, Satellite RNAs and Prions: Folding of Nucleic Acids and Misfolding of Proteins. Viruses. 2024 02 26; 16(3).
Steger G, Riesner D, Prusiner SB. PMID: 38543726; PMCID: PMC10975798.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Guam ALS-PDC is a distinct double-prion disorder featuring both tau and Aβ prions. Proc Natl Acad Sci U S A. 2023 03 28; 120(13):e2220984120.
Condello C, Ayers JI, Dalgard CL, Garcia Garcia MM, Rivera BM, Seeley WW, Perl DP, Prusiner SB. PMID: 36952379; PMCID: PMC10068802.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Aβ and Tau Prions Causing Alzheimer's Disease. Methods Mol Biol. 2023; 2561:293-337.
Condello C, Merz GE, Aoyagi A, DeGrado WF, Prusiner SB. PMID: 36399277.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Aβ and tau prions feature in the neuropathogenesis of Down syndrome. Proc Natl Acad Sci U S A. 2022 11 16; 119(46):e2212954119.
Condello C, Maxwell AM, Castillo E, Aoyagi A, Graff C, Ingelsson M, Lannfelt L, Bird TD, Keene CD, Seeley WW, Perl DP, Head E, Prusiner SB. PMID: 36343257; PMCID: PMC9674250.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Multiple system atrophy prions transmit neurological disease to mice expressing wild-type human α-synuclein. Acta Neuropathol. 2022 10; 144(4):677-690.
Holec SAM, Lee J, Oehler A, Ooi FK, Mordes DA, Olson SH, Prusiner SB, Woerman AL. PMID: 36018376; PMCID: PMC9636591.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Trans-channel fluorescence learning improves high-content screening for Alzheimer's disease therapeutics. Nat Mach Intell. 2022 Jun; 4(6):583-595.
Wong DR, Conrad J, Johnson N, Ayers J, Laeremans A, Lee JC, Lee J, Prusiner SB, Bandyopadhyay S, Butte AJ, Paras NA, Keiser MJ. PMID: 36276634; PMCID: PMC9585544.
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PubMed Mentions:
5
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Different α-synuclein prion strains cause dementia with Lewy bodies and multiple system atrophy. Proc Natl Acad Sci U S A. 2022 02 08; 119(6).
Ayers JI, Lee J, Monteiro O, Woerman AL, Lazar AA, Condello C, Paras NA, Prusiner SB. PMID: 35115402; PMCID: PMC8833220.
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PubMed Mentions:
30 Fields:
Translation:
HumansCells
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How an Infection of Sheep Revealed Prion Mechanisms in Alzheimer's Disease and Other Neurodegenerative Disorders. Int J Mol Sci. 2021 May 04; 22(9).
Carlson GA, Prusiner SB. PMID: 34064393; PMCID: PMC8125442.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Water-Soluble Iridium Photoredox Catalyst for the Trifluoromethylation of Biomolecule Substrates in Phosphate Buffered Saline Solvent. Org Lett. 2021 05 21; 23(10):3823-3827.
Nguyen TH, O'Brien CJ, Tran MLN, Olson SH, Settineri NS, Prusiner SB, Paras NA, Conrad J. PMID: 33929208.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components. Neuron. 2021 05 19; 109(10):1675-1691.e9.
Lester E, Ooi FK, Bakkar N, Ayers J, Woerman AL, Wheeler J, Bowser R, Carlson GA, Prusiner SB, Parker R. PMID: 33848474; PMCID: PMC8141031.
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PubMed Mentions:
75 Fields:
Translation:
HumansAnimalsCells
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Silver Benzoate Facilitates the Copper-Catalyzed C-N Coupling of Iodoazoles with Aromatic Nitrogen Heterocycles. ACS Omega. 2021 Apr 13; 6(14):9804-9812.
Lozano C, Ramirez C, Sin N, Viart HM, Prusiner SB, Paras NA, Conrad J. PMID: 33869960; PMCID: PMC8047741.
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PubMed Mentions:
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Prion biology: implications for Alzheimer's disease therapeutics. Lancet Neurol. 2020 10; 19(10):802-803.
Condello C, DeGrado WF, Prusiner SB. PMID: 32949533.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Expanding spectrum of prion diseases. Emerg Top Life Sci. 2020 09 08; 4(2):155-167.
Ayers JI, Paras NA, Prusiner SB. PMID: 32803268.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Prion protein - mediator of toxicity in multiple proteinopathies. Nat Rev Neurol. 2020 04; 16(4):187-188.
Ayers JI, Prusiner SB. PMID: 32123368.
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PubMed Mentions:
2 Fields:
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Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy. PLoS Pathog. 2020 02; 16(2):e1008222.
Woerman AL, Patel S, Kazmi SA, Oehler A, Lee J, Mordes DA, Olson SH, Prusiner SB. PMID: 32017806; PMCID: PMC6999861.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimals
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Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity. ACS Med Chem Lett. 2020 Feb 13; 11(2):127-132.
Grandjean JM, Jiu AY, West JW, Aoyagi A, Droege DG, Elepano M, Hirasawa M, Hirouchi M, Murakami R, Lee J, Sasaki K, Hirano S, Ohyama T, Tang BC, Vaz RJ, Inoue M, Olson SH, Prusiner SB, Conrad J, Paras NA. PMID: 32071678; PMCID: PMC7025388.
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PubMed Mentions:
3
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Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human α-synuclein. Acta Neuropathol Commun. 2019 05 20; 7(1):81.
Krejciova Z, Carlson GA, Giles K, Prusiner SB. PMID: 31109379; PMCID: PMC6526619.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Aβ and tau prion-like activities decline with longevity in the Alzheimer's disease human brain. Sci Transl Med. 2019 05 01; 11(490).
Aoyagi A, Condello C, Stöhr J, Yue W, Rivera BM, Lee JC, Woerman AL, Halliday G, van Duinen S, Ingelsson M, Lannfelt L, Graff C, Bird TD, Keene CD, Seeley WW, DeGrado WF, Prusiner SB. PMID: 31043574; PMCID: PMC6640844.
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PubMed Mentions:
64 Fields:
Translation:
HumansAnimalsCells
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Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCA*A53T) mouse lines. Acta Neuropathol. 2019 03; 137(3):437-454.
Woerman AL, Oehler A, Kazmi SA, Lee J, Halliday GM, Middleton LT, Gentleman SM, Mordes DA, Spina S, Grinberg LT, Olson SH, Prusiner SB. PMID: 30690664; PMCID: PMC6454887.
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PubMed Mentions:
52 Fields:
Translation:
HumansAnimals
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α-Synuclein: Multiple System Atrophy Prions. Cold Spring Harb Perspect Med. 2018 07 02; 8(7).
Woerman AL, Watts JC, Aoyagi A, Giles K, Middleton LT, Prusiner SB. PMID: 28213437; PMCID: PMC5561534.
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PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
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Citations must default to the online publication date. Nature. 2018 06; 558(7711):519.
Keller M, Prusiner S. PMID: 29950625.
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PubMed Mentions: Fields:
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β-Amyloid Prions and the Pathobiology of Alzheimer's Disease. Cold Spring Harb Perspect Med. 2018 05 01; 8(5).
Watts JC, Prusiner SB. PMID: 28193770; PMCID: PMC5554751.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimals
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A long-lived Aβ oligomer resistant to fibrillization. Biopolymers. 2018 Aug; 109(8):e23096.
Nick M, Wu Y, Schmidt NW, Prusiner SB, Stöhr J, DeGrado WF. PMID: 29319162; PMCID: PMC6039285.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer's disease. Proc Natl Acad Sci U S A. 2018 01 23; 115(4):E782-E791.
Condello C, Lemmin T, Stöhr J, Nick M, Wu Y, Maxwell AM, Watts JC, Caro CD, Oehler A, Keene CD, Bird TD, van Duinen SG, Lannfelt L, Ingelsson M, Graff C, Giles K, DeGrado WF, Prusiner SB. PMID: 29311311; PMCID: PMC5789926.
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PubMed Mentions:
70 Fields:
Translation:
AnimalsCells
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Familial Parkinson's point mutation abolishes multiple system atrophy prion replication. Proc Natl Acad Sci U S A. 2018 01 09; 115(2):409-414.
Woerman AL, Kazmi SA, Patel S, Aoyagi A, Oehler A, Widjaja K, Mordes DA, Olson SH, Prusiner SB. PMID: 29279394; PMCID: PMC5777081.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice. Proc Natl Acad Sci U S A. 2017 12 19; 114(51):E11029-E11036.
Johnson NR, Condello C, Guan S, Oehler A, Becker J, Gavidia M, Carlson GA, Giles K, Prusiner SB. PMID: 29203673; PMCID: PMC5754811.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Kinetics of Human Mutant Tau Prion Formation in the Brains of 2 Transgenic Mouse Lines. JAMA Neurol. 2017 12 01; 74(12):1464-1472.
Woerman AL, Patel S, Kazmi SA, Oehler A, Freyman Y, Espiritu L, Cotter R, Castaneda JA, Olson SH, Prusiner SB. PMID: 29059326; PMCID: PMC5822201.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimals
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A novel vector for transgenesis in the rat CNS. Acta Neuropathol Commun. 2017 Nov 21; 5(1):84.
Lopez TP, Giles K, Dugger BN, Oehler A, Condello C, Krejciova Z, Castaneda JA, Carlson GA, Prusiner SB. PMID: 29157304; PMCID: PMC5697436.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Experimental Models of Inherited PrP Prion Diseases. Cold Spring Harb Perspect Med. 2017 Nov 01; 7(11).
Watts JC, Prusiner SB. PMID: 28096244; PMCID: PMC5513788.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
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MSA prions exhibit remarkable stability and resistance to inactivation. Acta Neuropathol. 2018 01; 135(1):49-63.
Woerman AL, Kazmi SA, Patel S, Freyman Y, Oehler A, Aoyagi A, Mordes DA, Halliday GM, Middleton LT, Gentleman SM, Olson SH, Prusiner SB. PMID: 28849371; PMCID: PMC5756500.
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PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
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Bioassays and Inactivation of Prions. Cold Spring Harb Perspect Biol. 2017 Aug 01; 9(8).
Giles K, Woerman AL, Berry DB, Prusiner SB. PMID: 28246183; PMCID: PMC5538415.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimals
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Developing Therapeutics for PrP Prion Diseases. Cold Spring Harb Perspect Med. 2017 Apr 03; 7(4).
Giles K, Olson SH, Prusiner SB. PMID: 28096242; PMCID: PMC5378016.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells. Nat Chem. 2017 09; 9(9):874-881.
Stöhr J, Wu H, Nick M, Wu Y, Bhate M, Condello C, Johnson N, Rodgers J, Lemmin T, Acharya S, Becker J, Robinson K, Kelly MJS, Gai F, Stubbs G, Prusiner SB, DeGrado WF. PMID: 28837163; PMCID: PMC5759337.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Tau prions from Alzheimer's disease and chronic traumatic encephalopathy patients propagate in cultured cells. Proc Natl Acad Sci U S A. 2016 12 13; 113(50):E8187-E8196.
Woerman AL, Aoyagi A, Patel S, Kazmi SA, Lobach I, Grinberg LT, McKee AC, Seeley WW, Olson SH, Prusiner SB. PMID: 27911827; PMCID: PMC5167200.
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PubMed Mentions:
97 Fields:
Translation:
HumansCells
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Guinea Pig Prion Protein Supports Rapid Propagation of Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease Prions. J Virol. 2016 11 01; 90(21):9558-9569.
Watts JC, Giles K, Saltzberg DJ, Dugger BN, Patel S, Oehler A, Bhardwaj S, Sali A, Prusiner SB. PMID: 27440899; PMCID: PMC5068510.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Structural Polymorphism of Alzheimer's β-Amyloid Fibrils as Controlled by an E22 Switch: A Solid-State NMR Study. J Am Chem Soc. 2016 08 10; 138(31):9840-52.
Elkins MR, Wang T, Nick M, Jo H, Lemmin T, Prusiner SB, DeGrado WF, Stöhr J, Hong M. PMID: 27414264; PMCID: PMC5149419.
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PubMed Mentions:
43 Fields:
Translation:
HumansCells
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FoxO3 regulates neuronal reprogramming of cells from postnatal and aging mice. Proc Natl Acad Sci U S A. 2016 07 26; 113(30):8514-9.
Ahlenius H, Chanda S, Webb AE, Yousif I, Karmazin J, Prusiner SB, Brunet A, Südhof TC, Wernig M. PMID: 27402759; PMCID: PMC4968717.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Towards authentic transgenic mouse models of heritable PrP prion diseases. Acta Neuropathol. 2016 10; 132(4):593-610.
Watts JC, Giles K, Bourkas ME, Patel S, Oehler A, Gavidia M, Bhardwaj S, Lee J, Prusiner SB. PMID: 27350609; PMCID: PMC5152593.
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PubMed Mentions:
29 Fields:
Translation:
Animals
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Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice. J Pharmacol Exp Ther. 2016 09; 358(3):537-47.
Giles K, Berry DB, Condello C, Dugger BN, Li Z, Oehler A, Bhardwaj S, Elepano M, Guan S, Silber BM, Olson SH, Prusiner SB. PMID: 27317802; PMCID: PMC4998675.
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PubMed Mentions:
14 Fields:
Translation:
Animals
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Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism. Proc Natl Acad Sci U S A. 2015 Sep 22; 112(38):E5308-17.
Prusiner SB, Woerman AL, Mordes DA, Watts JC, Rampersaud R, Berry DB, Patel S, Oehler A, Lowe JK, Kravitz SN, Geschwind DH, Glidden DV, Halliday GM, Middleton LT, Gentleman SM, Grinberg LT, Giles K. PMID: 26324905; PMCID: PMC4586853.
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PubMed Mentions:
373 Fields:
Translation:
HumansAnimalsCells
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Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation. Ann Neurol. 2015 Oct; 78(4):540-53.
Watts JC, Giles K, Serban A, Patel S, Oehler A, Bhardwaj S, Guan S, Greicius MD, Miller BL, DeArmond SJ, Geschwind MD, Prusiner SB. PMID: 26094969; PMCID: PMC4711268.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimals
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Prion Protein-Antibody Complexes Characterized by Chromatography-Coupled Small-Angle X-Ray Scattering. Biophys J. 2015 Aug 18; 109(4):793-805.
Carter L, Kim SJ, Schneidman-Duhovny D, Stöhr J, Poncet-Montange G, Weiss TM, Tsuruta H, Prusiner SB, Sali A. PMID: 26287631; PMCID: PMC4547163.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Propagation of prions causing synucleinopathies in cultured cells. Proc Natl Acad Sci U S A. 2015 Sep 01; 112(35):E4949-58.
Woerman AL, Stöhr J, Aoyagi A, Rampersaud R, Krejciova Z, Watts JC, Ohyama T, Patel S, Widjaja K, Oehler A, Sanders DW, Diamond MI, Seeley WW, Middleton LT, Gentleman SM, Mordes DA, Südhof TC, Giles K, Prusiner SB. PMID: 26286986; PMCID: PMC4568231.
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PubMed Mentions:
138 Fields:
Translation:
HumansAnimalsCells
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Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains. J Pharmacol Exp Ther. 2015 Oct; 355(1):2-12.
Giles K, Berry DB, Condello C, Hawley RC, Gallardo-Godoy A, Bryant C, Oehler A, Elepano M, Bhardwaj S, Patel S, Silber BM, Guan S, DeArmond SJ, Renslo AR, Prusiner SB. PMID: 26224882; PMCID: PMC4576665.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimals
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Use of a 2-aminothiazole to Treat Chronic Wasting Disease in Transgenic Mice. J Infect Dis. 2015 Jul 15; 212 Suppl 1:S17-25.
Berry D, Giles K, Oehler A, Bhardwaj S, DeArmond SJ, Prusiner SB. PMID: 26116725; PMCID: PMC4551108.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Structural studies of truncated forms of the prion protein PrP. Biophys J. 2015 Mar 24; 108(6):1548-1554.
Wan W, Wille H, Stöhr J, Kendall A, Bian W, McDonald M, Tiggelaar S, Watts JC, Prusiner SB, Stubbs G. PMID: 25809267; PMCID: PMC4375555.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Mechanism of scrapie prion precipitation with phosphotungstate anions. ACS Chem Biol. 2015 May 15; 10(5):1269-77.
Levine DJ, Stöhr J, Falese LE, Ollesch J, Wille H, Prusiner SB, Long JR. PMID: 25695325; PMCID: PMC4437617.
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PubMed Mentions:
18 Fields:
Translation:
Animals
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Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients. Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28):10323-8.
Watts JC, Condello C, Stöhr J, Oehler A, Lee J, DeArmond SJ, Lannfelt L, Ingelsson M, Giles K, Prusiner SB. PMID: 24982139; PMCID: PMC4104857.
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PubMed Mentions:
162 Fields:
Translation:
HumansAnimals
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Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice. Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28):10329-34.
Stöhr J, Condello C, Watts JC, Bloch L, Oehler A, Nick M, DeArmond SJ, Giles K, DeGrado WF, Prusiner SB. PMID: 24982137; PMCID: PMC4104853.
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PubMed Mentions:
99 Fields:
Translation:
HumansAnimals
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Mouse models for studying the formation and propagation of prions. J Biol Chem. 2014 Jul 18; 289(29):19841-9.
Watts JC, Prusiner SB. PMID: 24860095; PMCID: PMC4106304.
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PubMed Mentions:
56 Fields:
Translation:
HumansAnimals
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Evidence that bank vole PrP is a universal acceptor for prions. PLoS Pathog. 2014 Apr; 10(4):e1003990.
Watts JC, Giles K, Patel S, Oehler A, DeArmond SJ, Prusiner SB. PMID: 24699458; PMCID: PMC3974871.
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PubMed Mentions:
67 Fields:
Translation:
HumansAnimals
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Novel compounds lowering the cellular isoform of the human prion protein in cultured human cells. Bioorg Med Chem. 2014 Mar 15; 22(6):1960-72.
Silber BM, Gever JR, Rao S, Li Z, Renslo AR, Widjaja K, Wong C, Giles K, Freyman Y, Elepano M, Irwin JJ, Jacobson MP, Prusiner SB. PMID: 24530226; PMCID: PMC3984052.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Transmission of multiple system atrophy prions to transgenic mice. Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48):19555-60.
Watts JC, Giles K, Oehler A, Middleton L, Dexter DT, Gentleman SM, DeArmond SJ, Prusiner SB. PMID: 24218576; PMCID: PMC3845125.
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PubMed Mentions:
230 Fields:
Translation:
HumansAnimalsPHPublic Health
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Drug resistance confounding prion therapeutics. Proc Natl Acad Sci U S A. 2013 Oct 29; 110(44):E4160-9.
Berry DB, Lu D, Geva M, Watts JC, Bhardwaj S, Oehler A, Renslo AR, DeArmond SJ, Prusiner SB, Giles K. PMID: 24128760; PMCID: PMC3816483.
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PubMed Mentions:
70 Fields:
Translation:
HumansAnimalsCells
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Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease. Neurology. 2013 Dec 03; 81(23):2015-23.
Geschwind MD, Kuo AL, Wong KS, Haman A, Devereux G, Raudabaugh BJ, Johnson DY, Torres-Chae CC, Finley R, Garcia P, Thai JN, Cheng HQ, Neuhaus JM, Forner SA, Duncan JL, Possin KL, Dearmond SJ, Prusiner SB, Miller BL. PMID: 24122181; PMCID: PMC4211922.
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PubMed Mentions:
53 Fields:
Translation:
Humans
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Antiprion compounds that reduce PrP(Sc) levels in dividing and stationary-phase cells. Bioorg Med Chem. 2013 Dec 15; 21(24):7999-8012.
Silber BM, Gever JR, Li Z, Gallardo-Godoy A, Renslo AR, Widjaja K, Irwin JJ, Rao S, Jacobson MP, Ghaemmaghami S, Prusiner SB. PMID: 24183589; PMCID: PMC3984054.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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A high-throughput screening assay for determining cellular levels of total tau protein. Curr Alzheimer Res. 2013 Sep; 10(7):679-87.
Dehdashti SJ, Zheng W, Gever JR, Wilhelm R, Nguyen DT, Sittampalam G, McKew JC, Austin CP, Prusiner SB. PMID: 23905996; PMCID: PMC4010324.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice. J Pharmacol Exp Ther. 2013 Nov; 347(2):325-38.
Lu D, Giles K, Li Z, Rao S, Dolghih E, Gever JR, Geva M, Elepano ML, Oehler A, Bryant C, Renslo AR, Jacobson MP, Dearmond SJ, Silber BM, Prusiner SB. PMID: 23965382; PMCID: PMC3807058.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCellsPHPublic Health
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Optimization of Arylamides as Novel, Potent and Brain-penetrant Antiprion Lead Compounds. ACS Med Chem Lett. 2013 Jul 11; 4(7):647-650.
Li Z, Rao S, Gever JR, Widjaja K, Prusiner SB, Silber BM. PMID: 23977416; PMCID: PMC3746989.
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PubMed Mentions:
6
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Plasma membrane invaginations containing clusters of full-length PrPSc are an early form of prion-associated neuropathology in vivo. Neurobiol Aging. 2013 Jun; 34(6):1621-31.
Godsave SF, Wille H, Pierson J, Prusiner SB, Peters PJ. PMID: 23481568; PMCID: PMC3596824.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Discovery and Preliminary SAR of Arylpiperazines as Novel, Brainpenetrant Antiprion Compounds. ACS Med Chem Lett. 2013 Apr 11; 4(4):397-401.
Li Z, Gever J, Rao S, Widjaja K, Prusiner SB, Silber BM. PMID: 23847718; PMCID: PMC3704178.
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PubMed Mentions:
6
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2-Aminothiazoles with improved pharmacotherapeutic properties for treatment of prion disease. ChemMedChem. 2013 May; 8(5):847-57.
Li Z, Silber BM, Rao S, Gever JR, Bryant C, Gallardo-Godoy A, Dolghih E, Widjaja K, Elepano M, Jacobson MP, Prusiner SB, Renslo AR. PMID: 23509039; PMCID: PMC3984044.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Convergent replication of mouse synthetic prion strains. Am J Pathol. 2013 Mar; 182(3):866-74.
Ghaemmaghami S, Colby DW, Nguyen HO, Hayashi S, Oehler A, DeArmond SJ, Prusiner SB. PMID: 23438476; PMCID: PMC3586687.
View in:
PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
Pharmacokinetics and metabolism of 2-aminothiazoles with antiprion activity in mice. Pharm Res. 2013 Apr; 30(4):932-50.
Silber BM, Rao S, Fife KL, Gallardo-Godoy A, Renslo AR, Dalvie DK, Giles K, Freyman Y, Elepano M, Gever JR, Li Z, Jacobson MP, Huang Y, Benet LZ, Prusiner SB. PMID: 23417511; PMCID: PMC3640342.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
-
Biology and genetics of prions causing neurodegeneration. Annu Rev Genet. 2013; 47:601-23.
Prusiner SB. PMID: 24274755; PMCID: PMC4010318.
View in:
PubMed Mentions:
229 Fields:
Translation:
HumansAnimalsCells
-
Chimeric elk/mouse prion proteins in transgenic mice. J Gen Virol. 2013 Feb; 94(Pt 2):443-452.
Tamgüney G, Giles K, Oehler A, Johnson NL, DeArmond SJ, Prusiner SB. PMID: 23100369; PMCID: PMC3709613.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsPHPublic Health
-
Novel epitopes identified by anti-PrP monoclonal antibodies produced following immunization of Prnp0/0 Balb/cJ mice with purified scrapie prions. Hybridoma (Larchmt). 2012 Oct; 31(5):314-24.
Stanker LH, Scotcher MC, Lin A, McGarvey J, Prusiner SB, Hnasko R. PMID: 23098297; PMCID: PMC3482378.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
-
Pharmacokinetics of quinacrine efflux from mouse brain via the P-glycoprotein efflux transporter. PLoS One. 2012; 7(7):e39112.
Ahn M, Ghaemmaghami S, Huang Y, Phuan PW, May BC, Giles K, DeArmond SJ, Prusiner SB. PMID: 22768295; PMCID: PMC3388068.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals
-
Cell biology. A unifying role for prions in neurodegenerative diseases. Science. 2012 Jun 22; 336(6088):1511-3.
Prusiner SB. PMID: 22723400; PMCID: PMC3942086.
View in:
PubMed Mentions:
234 Fields:
Translation:
HumansAnimalsCells
-
Purified and synthetic Alzheimer's amyloid beta (Aβ) prions. Proc Natl Acad Sci U S A. 2012 Jul 03; 109(27):11025-30.
Stöhr J, Watts JC, Mensinger ZL, Oehler A, Grillo SK, DeArmond SJ, Prusiner SB, Giles K. PMID: 22711819; PMCID: PMC3390876.
View in:
PubMed Mentions:
195 Fields:
Translation:
HumansAnimals
-
Degradation of fungal prion HET-s(218-289) induces formation of a generic amyloid fold. Biophys J. 2012 May 16; 102(10):2339-44.
Wan W, Wille H, Stöhr J, Baxa U, Prusiner SB, Stubbs G. PMID: 22677387; PMCID: PMC3353098.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
-
Compartment modeling for mammalian protein turnover studies by stable isotope metabolic labeling. Anal Chem. 2012 May 01; 84(9):4014-21.
Guan S, Price JC, Ghaemmaghami S, Prusiner SB, Burlingame AL. PMID: 22444387; PMCID: PMC3923578.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansAnimals
-
Identification of I137M and other mutations that modulate incubation periods for two human prion strains. J Virol. 2012 Jun; 86(11):6033-41.
Giles K, De Nicola GF, Patel S, Glidden DV, Korth C, Oehler A, DeArmond SJ, Prusiner SB. PMID: 22438549; PMCID: PMC3372217.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsPHPublic Health
-
Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein. Proc Natl Acad Sci U S A. 2012 Feb 28; 109(9):3498-503.
Watts JC, Giles K, Stöhr J, Oehler A, Bhardwaj S, Grillo SK, Patel S, DeArmond SJ, Prusiner SB. PMID: 22331873; PMCID: PMC3295307.
View in:
PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
-
Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice. Mol Ther Nucleic Acids. 2012 Feb 07; 1:e9.
Nazor Friberg K, Hung G, Wancewicz E, Giles K, Black C, Freier S, Bennett F, Dearmond SJ, Freyman Y, Lessard P, Ghaemmaghami S, Prusiner SB. PMID: 23344724; PMCID: PMC3381600.
View in:
PubMed Mentions:
24
-
Salivary prions in sheep and deer. Prion. 2012 Jan-Mar; 6(1):52-61.
Tamgüney G, Richt JA, Hamir AN, Greenlee JJ, Miller MW, Wolfe LL, Sirochman TM, Young AJ, Glidden DV, Johnson NL, Giles K, DeArmond SJ, Prusiner SB. PMID: 22453179; PMCID: PMC3338966.
View in:
PubMed Mentions:
27 Fields:
Translation:
Animals
-
Prion uptake in the gut: identification of the first uptake and replication sites. PLoS Pathog. 2011 Dec; 7(12):e1002449.
Kujala P, Raymond CR, Romeijn M, Godsave SF, van Kasteren SI, Wille H, Prusiner SB, Mabbott NA, Peters PJ. PMID: 22216002; PMCID: PMC3245311.
View in:
PubMed Mentions:
70 Fields:
Translation:
AnimalsCells
-
Spontaneous generation of anchorless prions in transgenic mice. Proc Natl Acad Sci U S A. 2011 Dec 27; 108(52):21223-8.
Stöhr J, Watts JC, Legname G, Oehler A, Lemus A, Nguyen HO, Sussman J, Wille H, DeArmond SJ, Prusiner SB, Giles K. PMID: 22160704; PMCID: PMC3248514.
View in:
PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
-
Protease-resistant prions selectively decrease Shadoo protein. PLoS Pathog. 2011 Nov; 7(11):e1002382.
Watts JC, Stöhr J, Bhardwaj S, Wille H, Oehler A, Dearmond SJ, Giles K, Prusiner SB. PMID: 22163178; PMCID: PMC3219722.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
-
De novo generation of prion strains. Nat Rev Microbiol. 2011 Sep 26; 9(11):771-7.
Colby DW, Prusiner SB. PMID: 21947062; PMCID: PMC3924856.
View in:
PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
-
A data processing pipeline for mammalian proteome dynamics studies using stable isotope metabolic labeling. Mol Cell Proteomics. 2011 Dec; 10(12):M111.010728.
Guan S, Price JC, Prusiner SB, Ghaemmaghami S, Burlingame AL. PMID: 21937731; PMCID: PMC3237081.
View in:
PubMed Mentions:
91 Fields:
Translation:
Animals
-
Conformational transformation and selection of synthetic prion strains. J Mol Biol. 2011 Oct 28; 413(3):527-42.
Ghaemmaghami S, Watts JC, Nguyen HO, Hayashi S, DeArmond SJ, Prusiner SB. PMID: 21839745; PMCID: PMC3195964.
View in:
PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
-
Conserved properties of human and bovine prion strains on transmission to guinea pigs. Lab Invest. 2011 Sep; 91(9):1326-36.
Safar JG, Giles K, Lessard P, Letessier F, Patel S, Serban A, Dearmond SJ, Prusiner SB. PMID: 21727894; PMCID: PMC3164925.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
-
A survey of antiprion compounds reveals the prevalence of non-PrP molecular targets. J Biol Chem. 2011 Aug 05; 286(31):27718-28.
Poncet-Montange G, St Martin SJ, Bogatova OV, Prusiner SB, Shoichet BK, Ghaemmaghami S. PMID: 21610081; PMCID: PMC3149362.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Bioluminescence imaging of Abeta deposition in bigenic mouse models of Alzheimer's disease. Proc Natl Acad Sci U S A. 2011 Feb 08; 108(6):2528-33.
Watts JC, Giles K, Grillo SK, Lemus A, DeArmond SJ, Prusiner SB. PMID: 21262831; PMCID: PMC3038719.
View in:
PubMed Mentions:
67 Fields:
Translation:
HumansAnimalsCells
-
2-Aminothiazoles as therapeutic leads for prion diseases. J Med Chem. 2011 Feb 24; 54(4):1010-21.
Gallardo-Godoy A, Gever J, Fife KL, Silber BM, Prusiner SB, Renslo AR. PMID: 21247166; PMCID: PMC3041857.
View in:
PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
-
Prions. Cold Spring Harb Perspect Biol. 2011 Jan 01; 3(1):a006833.
Colby DW, Prusiner SB. PMID: 21421910; PMCID: PMC3003464.
View in:
PubMed Mentions:
270 Fields:
Translation:
HumansAnimalsCells
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Analysis of proteome dynamics in the mouse brain. Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32):14508-13.
Price JC, Guan S, Burlingame A, Prusiner SB, Ghaemmaghami S. PMID: 20699386; PMCID: PMC2922600.
View in:
PubMed Mentions:
201 Fields:
Translation:
Animals
-
Human prion strain selection in transgenic mice. Ann Neurol. 2010 Aug; 68(2):151-61.
Giles K, Glidden DV, Patel S, Korth C, Groth D, Lemus A, DeArmond SJ, Prusiner SB. PMID: 20695008; PMCID: PMC2935907.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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Conformation-dependent high-affinity monoclonal antibodies to prion proteins. J Immunol. 2010 Jul 01; 185(1):729-37.
Stanker LH, Serban AV, Cleveland E, Hnasko R, Lemus A, Safar J, DeArmond SJ, Prusiner SB. PMID: 20530267; PMCID: PMC2957185.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Colloid formation by drugs in simulated intestinal fluid. J Med Chem. 2010 May 27; 53(10):4259-65.
Doak AK, Wille H, Prusiner SB, Shoichet BK. PMID: 20426472; PMCID: PMC2874266.
View in:
PubMed Mentions:
34 Fields:
Translation:
Cells
-
Generation of antisera to purified prions in lipid rafts. Prion. 2010 Apr-Jun; 4(2):94-104.
Hnasko R, Serban AV, Carlson G, Prusiner SB, Stanker LH. PMID: 20647769; PMCID: PMC2933057.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
-
Protease-sensitive synthetic prions. PLoS Pathog. 2010 Jan 22; 6(1):e1000736.
Colby DW, Wain R, Baskakov IV, Legname G, Palmer CG, Nguyen HO, Lemus A, Cohen FE, DeArmond SJ, Prusiner SB. PMID: 20107515; PMCID: PMC2809756.
View in:
PubMed Mentions:
105 Fields:
Translation:
AnimalsCells
-
Discovery of 2-aminothiazoles as potent antiprion compounds. J Virol. 2010 Apr; 84(7):3408-12.
Ghaemmaghami S, May BC, Renslo AR, Prusiner SB. PMID: 20032192; PMCID: PMC2838138.
View in:
PubMed Mentions:
50 Fields:
Translation:
AnimalsCells
-
Chemical induction of misfolded prion protein conformers in cell culture. J Biol Chem. 2010 Apr 02; 285(14):10415-23.
Ghaemmaghami S, Ullman J, Ahn M, St Martin S, Prusiner SB. PMID: 19955177; PMCID: PMC2856248.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
-
Continuous quinacrine treatment results in the formation of drug-resistant prions. PLoS Pathog. 2009 Nov; 5(11):e1000673.
Ghaemmaghami S, Ahn M, Lessard P, Giles K, Legname G, DeArmond SJ, Prusiner SB. PMID: 19956709; PMCID: PMC2777304.
View in:
PubMed Mentions:
78 Fields:
Translation:
AnimalsCells
-
Design and construction of diverse mammalian prion strains. Proc Natl Acad Sci U S A. 2009 Dec 01; 106(48):20417-22.
Colby DW, Giles K, Legname G, Wille H, Baskakov IV, DeArmond SJ, Prusiner SB. PMID: 19915150; PMCID: PMC2787151.
View in:
PubMed Mentions:
126 Fields:
Translation:
AnimalsCells
-
Natural and synthetic prion structure from X-ray fiber diffraction. Proc Natl Acad Sci U S A. 2009 Oct 06; 106(40):16990-5.
Wille H, Bian W, McDonald M, Kendall A, Colby DW, Bloch L, Ollesch J, Borovinskiy AL, Cohen FE, Prusiner SB, Stubbs G. PMID: 19805070; PMCID: PMC2761340.
View in:
PubMed Mentions:
111 Fields:
Translation:
AnimalsCells
-
Asymptomatic deer excrete infectious prions in faeces. Nature. 2009 Sep 24; 461(7263):529-32.
Tamgüney G, Miller MW, Wolfe LL, Sirochman TM, Glidden DV, Palmer C, Lemus A, DeArmond SJ, Prusiner SB. PMID: 19741608; PMCID: PMC3186440.
View in:
PubMed Mentions:
127 Fields:
Translation:
Animals
-
Prion proteins with pathogenic and protective mutations show similar structure and dynamics. Biochemistry. 2009 Sep 01; 48(34):8120-8.
Bae SH, Legname G, Serban A, Prusiner SB, Wright PE, Dyson HJ. PMID: 19618915; PMCID: PMC2762478.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Measuring prions by bioluminescence imaging. Proc Natl Acad Sci U S A. 2009 Sep 01; 106(35):15002-6.
Tamgüney G, Francis KP, Giles K, Lemus A, DeArmond SJ, Prusiner SB. PMID: 19706444; PMCID: PMC2736416.
View in:
PubMed Mentions:
36 Fields:
Translation:
Animals
-
Is Parkinson's disease a prion disorder? Proc Natl Acad Sci U S A. 2009 Aug 04; 106(31):12571-2.
Olanow CW, Prusiner SB. PMID: 19666621; PMCID: PMC2722298.
View in:
PubMed Mentions:
93 Fields:
Translation:
Humans
-
Prion proteins in subpopulations of white blood cells from patients with sporadic Creutzfeldt-Jakob disease. Lab Invest. 2009 Jun; 89(6):624-35.
Choi EM, Geschwind MD, Deering C, Pomeroy K, Kuo A, Miller BL, Safar JG, Prusiner SB. PMID: 19434060; PMCID: PMC2786774.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
-
Development of antibody fragments for immunotherapy of prion diseases. Biochem J. 2009 Mar 15; 418(3):507-15.
Campana V, Zentilin L, Mirabile I, Kranjc A, Casanova P, Giacca M, Prusiner SB, Legname G, Zurzolo C. PMID: 19000036.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
-
Transmission of scrapie and sheep-passaged bovine spongiform encephalopathy prions to transgenic mice expressing elk prion protein. J Gen Virol. 2009 Apr; 90(Pt 4):1035-1047.
Tamgüney G, Miller MW, Giles K, Lemus A, Glidden DV, DeArmond SJ, Prusiner SB. PMID: 19264659; PMCID: PMC2804060.
View in:
PubMed Mentions:
26 Fields:
Translation:
Animals
-
Surface charge of polyoxometalates modulates polymerization of the scrapie prion protein. Proc Natl Acad Sci U S A. 2009 Mar 10; 106(10):3740-5.
Wille H, Shanmugam M, Murugesu M, Ollesch J, Stubbs G, Long JR, Safar JG, Prusiner SB. PMID: 19223590; PMCID: PMC2656150.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
-
Cryo-immunogold electron microscopy for prions: toward identification of a conversion site. J Neurosci. 2008 Nov 19; 28(47):12489-99.
Godsave SF, Wille H, Kujala P, Latawiec D, DeArmond SJ, Serban A, Prusiner SB, Peters PJ. PMID: 19020041; PMCID: PMC2796247.
View in:
PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
-
Resistance of bovine spongiform encephalopathy (BSE) prions to inactivation. PLoS Pathog. 2008 Nov; 4(11):e1000206.
Giles K, Glidden DV, Beckwith R, Seoanes R, Peretz D, DeArmond SJ, Prusiner SB. PMID: 19008948; PMCID: PMC2576443.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
-
A gamma-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains. Proc Natl Acad Sci U S A. 2008 Jul 29; 105(30):10595-600.
Spilman P, Lessard P, Sattavat M, Bush C, Tousseyn T, Huang EJ, Giles K, Golde T, Das P, Fauq A, Prusiner SB, Dearmond SJ. PMID: 18647832; PMCID: PMC2492499.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
-
Genes contributing to prion pathogenesis. J Gen Virol. 2008 Jul; 89(Pt 7):1777-1788.
Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, Lisanti MP, Dwek RA, Rudd PM, Moskovitz J, Epstein CJ, Cruz TD, Kuziel WA, Maeda N, Sap J, Ashe KH, Carlson GA, Tesseur I, Wyss-Coray T, Mucke L, Weisgraber KH, Mahley RW, Cohen FE, Prusiner SB. PMID: 18559949; PMCID: PMC2828448.
View in:
PubMed Mentions:
66 Fields:
Translation:
HumansAnimals
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Transmission and detection of prions in feces. J Infect Dis. 2008 Jul 01; 198(1):81-9.
Safar JG, Lessard P, Tamgüney G, Freyman Y, Deering C, Letessier F, Dearmond SJ, Prusiner SB. PMID: 18505383; PMCID: PMC2803675.
View in:
PubMed Mentions:
78 Fields:
Translation:
Animals
-
Mechanisms of prion protein assembly into amyloid. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2409-14.
Stöhr J, Weinmann N, Wille H, Kaimann T, Nagel-Steger L, Birkmann E, Panza G, Prusiner SB, Eigen M, Riesner D. PMID: 18268326; PMCID: PMC2268150.
View in:
PubMed Mentions:
56 Fields:
Translation:
Cells
-
Small-molecule aggregates inhibit amyloid polymerization. Nat Chem Biol. 2008 Mar; 4(3):197-9.
Feng BY, Toyama BH, Wille H, Colby DW, Collins SR, May BC, Prusiner SB, Weissman J, Shoichet BK. PMID: 18223646; PMCID: PMC2730835.
View in:
PubMed Mentions:
102 Fields:
Translation:
AnimalsCells
-
Prion detection by an amyloid seeding assay. Proc Natl Acad Sci U S A. 2007 Dec 26; 104(52):20914-9.
Colby DW, Zhang Q, Wang S, Groth D, Legname G, Riesner D, Prusiner SB. PMID: 18096717; PMCID: PMC2409241.
View in:
PubMed Mentions:
117 Fields:
Translation:
HumansAnimalsCells
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Cell division modulates prion accumulation in cultured cells. Proc Natl Acad Sci U S A. 2007 Nov 13; 104(46):17971-6.
Ghaemmaghami S, Phuan PW, Perkins B, Ullman J, May BC, Cohen FE, Prusiner SB. PMID: 17989223; PMCID: PMC2084281.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansCells
-
Influence of water, fat, and glycerol on the mechanism of thermal prion inactivation. J Biol Chem. 2007 Dec 07; 282(49):35855-67.
Müller H, Stitz L, Wille H, Prusiner SB, Riesner D. PMID: 17878157.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Electron crystallography of the scrapie prion protein complexed with heavy metals. Arch Biochem Biophys. 2007 Nov 15; 467(2):239-48.
Wille H, Govaerts C, Borovinskiy A, Latawiec D, Downing KH, Cohen FE, Prusiner SB. PMID: 17935686; PMCID: PMC3557509.
View in:
PubMed Mentions:
17 Fields:
Translation:
Cells
-
Polio and Nobel prizes: looking back 50 years. Ann Neurol. 2007 May; 61(5):385-95.
Norrby E, Prusiner SB. PMID: 17469121.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Discriminating between cellular and misfolded prion protein by using affinity to 9-aminoacridine compounds. J Gen Virol. 2007 Apr; 88(Pt 4):1392-1401.
Phuan PW, Zorn JA, Safar J, Giles K, Prusiner SB, Cohen FE, May BCH. PMID: 17374787.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Phosphorothioate oligonucleotides reduce PrP levels and prion infectivity in cultured cells. Mol Med. 2007 Mar-Apr; 13(3-4):190-8.
Karpuj MV, Giles K, Gelibter-Niv S, Scott MR, Lingappa VR, Szoka FC, Peretz D, Denetclaw W, Prusiner SB. PMID: 17592554; PMCID: PMC1892763.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Transgenic mouse brains for the evaluation and quality control of BSE tests. Biol Chem. 2007 Mar; 388(3):349-54.
Philipp WJ, Groth D, Giles K, Vodrazka P, Schimmel H, Feyssaguet M, Toomik R, Schacher P, Osman AA, Lachmann I, Wear A, Arsac JN, Prusiner SB. PMID: 17338644.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Thioaptamer interactions with prion proteins: sequence-specific and non-specific binding sites. J Mol Biol. 2007 Jun 15; 369(4):1001-14.
King DJ, Safar JG, Legname G, Prusiner SB. PMID: 17481659.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics. J Med Chem. 2007 Jan 11; 50(1):65-73.
May BC, Zorn JA, Witkop J, Sherrill J, Wallace AC, Legname G, Prusiner SB, Cohen FE. PMID: 17201410.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
-
Developmental expression of PrP in the post-implantation embryo. Brain Res. 2007 Mar 30; 1139:60-7.
Tremblay P, Bouzamondo-Bernstein E, Heinrich C, Prusiner SB, DeArmond SJ. PMID: 17292334; PMCID: PMC2706582.
View in:
PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
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Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes. Proc Natl Acad Sci U S A. 2006 Dec 12; 103(50):19105-10.
Legname G, Nguyen HO, Peretz D, Cohen FE, DeArmond SJ, Prusiner SB. PMID: 17142317; PMCID: PMC1748184.
View in:
PubMed Mentions:
131 Fields:
Translation:
AnimalsCells
-
Transmission of elk and deer prions to transgenic mice. J Virol. 2006 Sep; 80(18):9104-14.
Tamgüney G, Giles K, Bouzamondo-Bernstein E, Bosque PJ, Miller MW, Safar J, DeArmond SJ, Prusiner SB. PMID: 16940522; PMCID: PMC1563923.
View in:
PubMed Mentions:
100 Fields:
Translation:
Animals
-
Expression mapping of tetracycline-responsive prion protein promoter: digital atlasing for generating cell-specific disease models. Neuroimage. 2006 Nov 01; 33(2):449-62.
Boy J, Leergaard TB, Schmidt T, Odeh F, Bichelmeier U, Nuber S, Holzmann C, Wree A, Prusiner SB, Bujard H, Riess O, Bjaalie JG. PMID: 16931059.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Structure-activity relationship study of 9-aminoacridine compounds in scrapie-infected neuroblastoma cells. Bioorg Med Chem Lett. 2006 Sep 15; 16(18):4913-6.
May BC, Witkop J, Sherrill J, Anderson MO, Madrid PB, Zorn JA, Prusiner SB, Cohen FE, Guy RK. PMID: 16860557.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation. J Mol Biol. 2006 Oct 13; 363(1):75-97.
Luginbühl B, Kanyo Z, Jones RM, Fletterick RJ, Prusiner SB, Cohen FE, Williamson RA, Burton DR, Plückthun A. PMID: 16962610.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansCells
-
Human prions and plasma lipoproteins. Proc Natl Acad Sci U S A. 2006 Jul 25; 103(30):11312-7.
Safar JG, Wille H, Geschwind MD, Deering C, Latawiec D, Serban A, King DJ, Legname G, Weisgraber KH, Mahley RW, Miller BL, Dearmond SJ, Prusiner SB. PMID: 16849426; PMCID: PMC1544083.
View in:
PubMed Mentions:
20 Fields:
Translation:
Humans
-
Copper induces conformational changes in the N-terminal part of cell-surface PrPC. Arch Virol. 2006 Nov; 151(11):2103-9.
Leclerc E, Serban H, Prusiner SB, Burton DR, Williamson RA. PMID: 16791441.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Changes in neuropeptide expression in mice infected with prions. Neurobiol Aging. 2007 May; 28(5):748-65.
Diez M, Groth D, DeArmond SJ, Prusiner SB, Hökfelt T. PMID: 16621165.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
-
Quinacrine is mainly metabolized to mono-desethyl quinacrine by CYP3A4/5 and its brain accumulation is limited by P-glycoprotein. Drug Metab Dispos. 2006 Jul; 34(7):1136-44.
Huang Y, Okochi H, May BC, Legname G, Prusiner SB, Benet LZ, Guglielmo BJ, Lin ET. PMID: 16581945.
View in:
PubMed Mentions:
16 Fields:
-
Prion infection of mouse neurospheres. Proc Natl Acad Sci U S A. 2006 Mar 07; 103(10):3875-80.
Giri RK, Young R, Pitstick R, DeArmond SJ, Prusiner SB, Carlson GA. PMID: 16495413; PMCID: PMC1533787.
View in:
PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
Inactivation of prions by acidic sodium dodecyl sulfate. J Virol. 2006 Jan; 80(1):322-31.
Peretz D, Supattapone S, Giles K, Vergara J, Freyman Y, Lessard P, Safar JG, Glidden DV, McCulloch C, Nguyen HO, Scott M, Dearmond SJ, Prusiner SB. PMID: 16352557; PMCID: PMC1317507.
View in:
PubMed Mentions:
46 Fields:
Translation:
HumansAnimals
-
Discovering DNA encodes heredity and prions are infectious proteins. Annu Rev Genet. 2006; 40:25-45.
Prusiner SB, McCarty M. PMID: 17094736.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
-
Recombinant prion protein induces rapid polarization and development of synapses in embryonic rat hippocampal neurons in vitro. J Neurochem. 2005 Dec; 95(5):1373-86.
Kanaani J, Prusiner SB, Diacovo J, Baekkeskov S, Legname G. PMID: 16313516.
View in:
PubMed Mentions:
79 Fields:
Translation:
AnimalsCells
-
Solid-state NMR structural studies of the fibril form of a mutant mouse prion peptide PrP89-143(P101L). Solid State Nucl Magn Reson. 2006 Feb; 29(1-3):183-90.
Lim KH, Nguyen TN, Damo SM, Mazur T, Ball HL, Prusiner SB, Pines A, Wemmer DE. PMID: 16256316.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
-
Selective precipitation of prions by polyoxometalate complexes. J Am Chem Soc. 2005 Oct 12; 127(40):13802-3.
Lee IS, Long JR, Prusiner SB, Safar JG. PMID: 16201796.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Prion clearance in bigenic mice. J Gen Virol. 2005 Oct; 86(Pt 10):2913-2923.
Safar JG, DeArmond SJ, Kociuba K, Deering C, Didorenko S, Bouzamondo-Bernstein E, Prusiner SB, Tremblay P. PMID: 16186247.
View in:
PubMed Mentions:
74 Fields:
Translation:
AnimalsCells
-
Search for a prion-specific nucleic acid. J Virol. 2005 Aug; 79(16):10796-806.
Safar JG, Kellings K, Serban A, Groth D, Cleaver JE, Prusiner SB, Riesner D. PMID: 16051871; PMCID: PMC1182634.
View in:
PubMed Mentions:
52 Fields:
Translation:
Animals
-
Assembly of natural and recombinant prion protein into fibrils. Biol Chem. 2005 Jun; 386(6):569-80.
Leffers KW, Wille H, Stöhr J, Junger E, Prusiner SB, Riesner D. PMID: 16006244.
View in:
PubMed Mentions:
30 Fields:
Translation:
Animals
-
Transmission barriers for bovine, ovine, and human prions in transgenic mice. J Virol. 2005 May; 79(9):5259-71.
Scott MR, Peretz D, Nguyen HO, Dearmond SJ, Prusiner SB. PMID: 15827140; PMCID: PMC1082721.
View in:
PubMed Mentions:
39 Fields:
Translation:
HumansAnimals
-
Diagnosis of human prion disease. Proc Natl Acad Sci U S A. 2005 Mar 01; 102(9):3501-6.
Safar JG, Geschwind MD, Deering C, Didorenko S, Sattavat M, Sanchez H, Serban A, Vey M, Baron H, Giles K, Miller BL, Dearmond SJ, Prusiner SB. PMID: 15741275; PMCID: PMC552933.
View in:
PubMed Mentions:
116 Fields:
Translation:
Humans
-
Strain-specified characteristics of mouse synthetic prions. Proc Natl Acad Sci U S A. 2005 Feb 08; 102(6):2168-73.
Legname G, Nguyen HO, Baskakov IV, Cohen FE, Dearmond SJ, Prusiner SB. PMID: 15671162; PMCID: PMC548557.
View in:
PubMed Mentions:
94 Fields:
Translation:
HumansAnimalsCells
-
Notch-1 activation and dendritic atrophy in prion disease. Proc Natl Acad Sci U S A. 2005 Jan 18; 102(3):886-91.
Ishikura N, Clever JL, Bouzamondo-Bernstein E, Samayoa E, Prusiner SB, Huang EJ, DeArmond SJ. PMID: 15640354; PMCID: PMC545568.
View in:
PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
-
Oxidation of methionine residues in the prion protein by hydrogen peroxide. Arch Biochem Biophys. 2004 Dec 15; 432(2):188-95.
Requena JR, Dimitrova MN, Legname G, Teijeira S, Prusiner SB, Levine RL. PMID: 15542057.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
-
Pharmacokinetics of quinacrine in the treatment of prion disease. BMC Infect Dis. 2004 Nov 29; 4:53.
Yung L, Huang Y, Lessard P, Legname G, Lin ET, Baldwin M, Prusiner SB, Ryou C, Guglielmo BJ. PMID: 15569390; PMCID: PMC535929.
View in:
PubMed Mentions:
18 Fields:
Translation:
Animals
-
Immunoglobulins in urine of hamsters with scrapie. J Biol Chem. 2004 Nov 19; 279(47):48817-20.
Serban A, Legname G, Hansen K, Kovaleva N, Prusiner SB. PMID: 15310752.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimals
-
The neurodegeneration sequence in prion diseases: evidence from functional, morphological and ultrastructural studies of the GABAergic system. J Neuropathol Exp Neurol. 2004 Aug; 63(8):882-99.
Bouzamondo-Bernstein E, Hopkins SD, Spilman P, Uyehara-Lock J, Deering C, Safar J, Prusiner SB, Ralston HJ, DeArmond SJ. PMID: 15330342.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
-
Synthetic mammalian prions. Science. 2004 Jul 30; 305(5684):673-6.
Legname G, Baskakov IV, Nguyen HO, Riesner D, Cohen FE, DeArmond SJ, Prusiner SB. PMID: 15286374.
View in:
PubMed Mentions:
398 Fields:
Translation:
AnimalsCells
-
Detecting mad cow disease. Sci Am. 2004 Jul; 291(1):86-93.
Prusiner SB. PMID: 15255592.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
-
Evidence for assembly of prions with left-handed beta-helices into trimers. Proc Natl Acad Sci U S A. 2004 Jun 01; 101(22):8342-7.
Govaerts C, Wille H, Prusiner SB, Cohen FE. PMID: 15155909; PMCID: PMC420396.
View in:
PubMed Mentions:
199 Fields:
Translation:
HumansCells
-
Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues. Nat Biotechnol. 2004 Jun; 22(6):724-31.
Schmitt-Ulms G, Hansen K, Liu J, Cowdrey C, Yang J, DeArmond SJ, Cohen FE, Prusiner SB, Baldwin MA. PMID: 15146195.
View in:
PubMed Mentions:
70 Fields:
Translation:
AnimalsCells
-
Prions: so many fibers, so little infectivity. Trends Biochem Sci. 2004 Apr; 29(4):162-5.
May BC, Govaerts C, Prusiner SB, Cohen FE. PMID: 15124628.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
The peculiar nature of unfolding of the human prion protein. Protein Sci. 2004 Mar; 13(3):586-95.
Baskakov IV, Legname G, Gryczynski Z, Prusiner SB. PMID: 14767078; PMCID: PMC2286731.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
-
When sporadic disease is not sporadic: the potential for genetic etiology. Arch Neurol. 2004 Feb; 61(2):213-6.
Goldman JS, Miller BL, Safar J, de Tourreil S, Martindale JL, Prusiner SB, Geschwind MD. PMID: 14967768.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Mutant PrPSc conformers induced by a synthetic peptide and several prion strains. J Virol. 2004 Feb; 78(4):2088-99.
Tremblay P, Ball HL, Kaneko K, Groth D, Hegde RS, Cohen FE, DeArmond SJ, Prusiner SB, Safar JG. PMID: 14747574; PMCID: PMC369494.
View in:
PubMed Mentions:
64 Fields:
Translation:
HumansAnimalsCells
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Early evidence that a protease-resistant protein is an active component of the infectious prion. Cell. 2004 Jan 23; 116(2 Suppl):S109, 1 p following S113.
Prusiner SB. PMID: 15055596.
View in:
PubMed Mentions:
9 Fields:
-
Trafficking of prion proteins through a caveolae-mediated endosomal pathway. J Cell Biol. 2003 Aug 18; 162(4):703-17.
Peters PJ, Mironov A, Peretz D, van Donselaar E, Leclerc E, Erpel S, DeArmond SJ, Burton DR, Williamson RA, Vey M, Prusiner SB. PMID: 12925711; PMCID: PMC2173792.
View in:
PubMed Mentions:
66 Fields:
Translation:
AnimalsCells
-
Cytosolic prion protein in neurons. J Neurosci. 2003 Aug 06; 23(18):7183-93.
Mironov A, Latawiec D, Wille H, Bouzamondo-Bernstein E, Legname G, Williamson RA, Burton D, DeArmond SJ, Prusiner SB, Peters PJ. PMID: 12904479; PMCID: PMC6740654.
View in:
PubMed Mentions:
71 Fields:
Translation:
AnimalsCells
-
Copper coordination in the full-length, recombinant prion protein. Biochemistry. 2003 Jun 10; 42(22):6794-803.
Burns CS, Aronoff-Spencer E, Legname G, Prusiner SB, Antholine WE, Gerfen GJ, Peisach J, Millhauser GL. PMID: 12779334; PMCID: PMC2905145.
View in:
PubMed Mentions:
72 Fields:
Translation:
AnimalsCells
-
Differential inhibition of prion propagation by enantiomers of quinacrine. Lab Invest. 2003 Jun; 83(6):837-43.
Ryou C, Legname G, Peretz D, Craig JC, Baldwin MA, Prusiner SB. PMID: 12808118.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
-
Cooperative binding of dominant-negative prion protein to kringle domains. J Mol Biol. 2003 May 30; 329(2):323-33.
Ryou C, Prusiner SB, Legname G. PMID: 12758079.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
-
Abbreviated incubation times for human prions in mice expressing a chimeric mouse-human prion protein transgene. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4784-9.
Korth C, Kaneko K, Groth D, Heye N, Telling G, Mastrianni J, Parchi P, Gambetti P, Will R, Ironside J, Heinrich C, Tremblay P, DeArmond SJ, Prusiner SB. PMID: 12684540; PMCID: PMC153633.
View in:
PubMed Mentions:
71 Fields:
Translation:
HumansAnimals
-
Potent inhibition of scrapie prion replication in cultured cells by bis-acridines. Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6):3416-21.
May BC, Fafarman AT, Hong SB, Rogers M, Deady LW, Prusiner SB, Cohen FE. PMID: 12626750; PMCID: PMC152307.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
-
Perspectives on prion biology, prion disease pathogenesis, and pharmacologic approaches to treatment. Clin Lab Med. 2003 Mar; 23(1):1-41.
DeArmond SJ, Prusiner SB. PMID: 12733423.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansAnimals
-
Conformation of PrP(C) on the cell surface as probed by antibodies. J Mol Biol. 2003 Feb 14; 326(2):475-83.
Leclerc E, Peretz D, Ball H, Solforosi L, Legname G, Safar J, Serban A, Prusiner SB, Burton DR, Williamson RA. PMID: 12559915.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
-
The PrP-like protein Doppel binds copper. J Biol Chem. 2003 Mar 14; 278(11):8888-96.
Qin K, Coomaraswamy J, Mastrangelo P, Yang Y, Lugowski S, Petromilli C, Prusiner SB, Fraser PE, Goldberg JM, Chakrabartty A, Westaway D. PMID: 12482851.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
Historical essay. Discovering the cause of AIDS. Science. 2002 Nov 29; 298(5599):1726.
Prusiner SB. PMID: 12459574.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
-
Prion and doppel proteins bind to granule cells of the cerebellum. Proc Natl Acad Sci U S A. 2002 Dec 10; 99(25):16285-90.
Legname G, Nelken P, Guan Z, Kanyo ZF, DeArmond SJ, Prusiner SB. PMID: 12446843; PMCID: PMC138603.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
-
Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice. Nat Biotechnol. 2002 Nov; 20(11):1147-50.
Safar JG, Scott M, Monaghan J, Deering C, Didorenko S, Vergara J, Ball H, Legname G, Leclerc E, Solforosi L, Serban H, Groth D, Burton DR, Prusiner SB, Williamson RA. PMID: 12389035.
View in:
PubMed Mentions:
94 Fields:
Translation:
HumansAnimalsPHPublic Health
-
Locally disordered conformer of the hamster prion protein: a crucial intermediate to PrPSc? Biochemistry. 2002 Oct 15; 41(41):12277-83.
Kuwata K, Li H, Yamada H, Legname G, Prusiner SB, Akasaka K, James TL. PMID: 12369815.
View in:
PubMed Mentions:
34 Fields:
Translation:
AnimalsCells
-
Dominant-negative inhibition of prion replication in transgenic mice. Proc Natl Acad Sci U S A. 2002 Oct 01; 99(20):13079-84.
Perrier V, Kaneko K, Safar J, Vergara J, Tremblay P, DeArmond SJ, Cohen FE, Prusiner SB, Wallace AC. PMID: 12271119; PMCID: PMC130589.
View in:
PubMed Mentions:
68 Fields:
Translation:
HumansAnimalsCells
-
A change in the conformation of prions accompanies the emergence of a new prion strain. Neuron. 2002 Jun 13; 34(6):921-32.
Peretz D, Williamson RA, Legname G, Matsunaga Y, Vergara J, Burton DR, DeArmond SJ, Prusiner SB, Scott MR. PMID: 12086640.
View in:
PubMed Mentions:
116 Fields:
Translation:
HumansAnimalsCells
-
Pathway complexity of prion protein assembly into amyloid. J Biol Chem. 2002 Jun 14; 277(24):21140-8.
Baskakov IV, Legname G, Baldwin MA, Prusiner SB, Cohen FE. PMID: 11912192.
View in:
PubMed Mentions:
143 Fields:
Translation:
AnimalsCells
-
Prions in skeletal muscle. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):3812-7.
Bosque PJ, Ryou C, Telling G, Peretz D, Legname G, DeArmond SJ, Prusiner SB. PMID: 11904434; PMCID: PMC122606.
View in:
PubMed Mentions:
48 Fields:
Translation:
AnimalsCellsPHPublic Health
-
Structural studies of the scrapie prion protein by electron crystallography. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):3563-8.
Wille H, Michelitsch MD, Guenebaut V, Supattapone S, Serban A, Cohen FE, Agard DA, Prusiner SB. PMID: 11891310; PMCID: PMC122563.
View in:
PubMed Mentions:
127 Fields:
Translation:
AnimalsCells
-
Differences between the prion protein and its homolog Doppel: a partially structured state with implications for scrapie formation. J Mol Biol. 2002 Feb 22; 316(3):807-15.
Nicholson EM, Mo H, Prusiner SB, Cohen FE, Marqusee S. PMID: 11866533.
View in:
PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
Inherited prion disease caused by the V210I mutation: transmission to transgenic mice. Neurology. 2001 Dec 26; 57(12):2198-205.
Mastrianni JA, Capellari S, Telling GC, Han D, Bosque P, Prusiner SB, DeArmond SJ. PMID: 11756597.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimals
-
Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein. J Mol Biol. 2001 Dec 14; 314(5):1209-25.
Schmitt-Ulms G, Legname G, Baldwin MA, Ball HL, Bradon N, Bosque PJ, Crossin KL, Edelman GM, DeArmond SJ, Cohen FE, Prusiner SB. PMID: 11743735.
View in:
PubMed Mentions:
119 Fields:
Translation:
AnimalsCells
-
Doppel-induced cerebellar degeneration in transgenic mice. Proc Natl Acad Sci U S A. 2001 Dec 18; 98(26):15288-93.
Moore RC, Mastrangelo P, Bouzamondo E, Heinrich C, Legname G, Prusiner SB, Hood L, Westaway D, DeArmond SJ, Tremblay P. PMID: 11734625; PMCID: PMC65022.
View in:
PubMed Mentions:
53 Fields:
Translation:
AnimalsCells
-
Engineering the prion protein using chemical synthesis. J Pept Res. 2001 Nov; 58(5):357-74.
Ball HL, King DS, Cohen FE, Prusiner SB, Baldwin MA. PMID: 11892845.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Huntington disease phenocopy is a familial prion disease. Am J Hum Genet. 2001 Dec; 69(6):1385-8.
Moore RC, Xiang F, Monaghan J, Han D, Zhang Z, Edström L, Anvret M, Prusiner SB. PMID: 11593450; PMCID: PMC1235549.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansCells
-
Induction of distinct [URE3] yeast prion strains. Mol Cell Biol. 2001 Oct; 21(20):7035-46.
Schlumpberger M, Prusiner SB, Herskowitz I. PMID: 11564886; PMCID: PMC99879.
View in:
PubMed Mentions:
90 Fields:
Translation:
AnimalsCells
-
Solid-state NMR studies of the secondary structure of a mutant prion protein fragment of 55 residues that induces neurodegeneration. Proc Natl Acad Sci U S A. 2001 Sep 25; 98(20):11686-90.
Laws DD, Bitter HM, Liu K, Ball HL, Kaneko K, Wille H, Cohen FE, Prusiner SB, Pines A, Wemmer DE. PMID: 11562491; PMCID: PMC58790.
View in:
PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
-
Antibodies inhibit prion propagation and clear cell cultures of prion infectivity. Nature. 2001 Aug 16; 412(6848):739-43.
Peretz D, Williamson RA, Kaneko K, Vergara J, Leclerc E, Schmitt-Ulms G, Mehlhorn IR, Legname G, Wormald MR, Rudd PM, Dwek RA, Burton DR, Prusiner SB. PMID: 11507642.
View in:
PubMed Mentions:
147 Fields:
Translation:
AnimalsCells
-
Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease. Proc Natl Acad Sci U S A. 2001 Aug 14; 98(17):9836-41.
Korth C, May BC, Cohen FE, Prusiner SB. PMID: 11504948; PMCID: PMC55539.
View in:
PubMed Mentions:
165 Fields:
Translation:
HumansAnimalsCells
-
Cryptic epitopes in N-terminally truncated prion protein are exposed in the full-length molecule: dependence of conformation on pH. Proteins. 2001 Aug 01; 44(2):110-8.
Matsunaga Y, Peretz D, Williamson A, Burton D, Mehlhorn I, Groth D, Cohen FE, Prusiner SB, Baldwin MA. PMID: 11391773.
View in:
PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
-
Decreased MK-801 binding in discrete hippocampal regions of prion-infected mice. Neurobiol Dis. 2001 Aug; 8(4):692-9.
Diez M, DeArmond SJ, Groth D, Prusiner SB, Hökfelt T. PMID: 11493033.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Copper-catalyzed oxidation of the recombinant SHa(29-231) prion protein. Proc Natl Acad Sci U S A. 2001 Jun 19; 98(13):7170-5.
Requena JR, Groth D, Legname G, Stadtman ER, Prusiner SB, Levine RL. PMID: 11404462; PMCID: PMC34641.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCells
-
Shattuck lecture--neurodegenerative diseases and prions. N Engl J Med. 2001 May 17; 344(20):1516-26.
Prusiner SB. PMID: 11357156.
View in:
PubMed Mentions:
204 Fields:
-
Folding of prion protein to its native alpha-helical conformation is under kinetic control. J Biol Chem. 2001 Jun 08; 276(23):19687-90.
Baskakov IV, Legname G, Prusiner SB, Cohen FE. PMID: 11306559.
View in:
PubMed Mentions:
67 Fields:
Translation:
Cells
-
Prion glycoprotein: structure, dynamics, and roles for the sugars. Biochemistry. 2001 Apr 03; 40(13):3759-66.
Rudd PM, Wormald MR, Wing DR, Prusiner SB, Dwek RA. PMID: 11300755.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
-
Immobilized prion protein undergoes spontaneous rearrangement to a conformation having features in common with the infectious form. EMBO J. 2001 Apr 02; 20(7):1547-54.
Leclerc E, Peretz D, Ball H, Sakurai H, Legname G, Serban A, Prusiner SB, Burton DR, Williamson RA. PMID: 11285219; PMCID: PMC145482.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Structural intermediates in the putative pathway from the cellular prion protein to the pathogenic form. Biol Chem. 2001 Apr; 382(4):683-91.
Jansen K, Schäfer O, Birkmann E, Post K, Serban H, Prusiner SB, Riesner D. PMID: 11405232.
View in:
PubMed Mentions:
21 Fields:
Translation:
Cells
-
Branched polyamines cure prion-infected neuroblastoma cells. J Virol. 2001 Apr; 75(7):3453-61.
Supattapone S, Wille H, Uyechi L, Safar J, Tremblay P, Szoka FC, Cohen FE, Prusiner SB, Scott MR. PMID: 11238871; PMCID: PMC114138.
View in:
PubMed Mentions:
48 Fields:
Translation:
HumansCells
-
Conformational propagation with prion-like characteristics in a simple model of protein folding. Protein Sci. 2001 Apr; 10(4):819-35.
Harrison PM, Chan HS, Prusiner SB, Cohen FE. PMID: 11274473; PMCID: PMC2373973.
View in:
PubMed Mentions:
21 Fields:
Translation:
Cells
-
Strain-specified relative conformational stability of the scrapie prion protein. Protein Sci. 2001 Apr; 10(4):854-63.
Peretz D, Scott MR, Groth D, Williamson RA, Burton DR, Cohen FE, Prusiner SB. PMID: 11274476; PMCID: PMC2373967.
View in:
PubMed Mentions:
130 Fields:
Translation:
AnimalsCells
-
A protease-resistant 61-residue prion peptide causes neurodegeneration in transgenic mice. Mol Cell Biol. 2001 Apr; 21(7):2608-16.
Supattapone S, Bouzamondo E, Ball HL, Wille H, Nguyen HO, Cohen FE, DeArmond SJ, Prusiner SB, Scott M. PMID: 11259607; PMCID: PMC86891.
View in:
PubMed Mentions:
16 Fields:
Translation:
Animals
-
Local structural plasticity of the prion protein. Analysis of NMR relaxation dynamics. Biochemistry. 2001 Mar 06; 40(9):2743-53.
Viles JH, Donne D, Kroon G, Prusiner SB, Cohen FE, Dyson HJ, Wright PE. PMID: 11258885.
View in:
PubMed Mentions:
58 Fields:
Translation:
AnimalsCells
-
Two different neurodegenerative diseases caused by proteins with similar structures. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2352-7.
Mo H, Moore RC, Cohen FE, Westaway D, Prusiner SB, Wright PE, Dyson HJ. PMID: 11226243; PMCID: PMC30142.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
-
Identification of two prion protein regions that modify scrapie incubation time. J Virol. 2001 Feb; 75(3):1408-13.
Supattapone S, Muramoto T, Legname G, Mehlhorn I, Cohen FE, DeArmond SJ, Prusiner SB, Scott MR. PMID: 11152514; PMCID: PMC114047.
View in:
PubMed Mentions:
53 Fields:
Translation:
Animals
-
Affinity-tagged miniprion derivatives spontaneously adopt protease-resistant conformations. J Virol. 2000 Dec; 74(24):11928-34.
Supattapone S, Nguyen HO, Muramoto T, Cohen FE, DeArmond SJ, Prusiner SB, Scott M. PMID: 11090193; PMCID: PMC112476.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Identification of the Cu2+ binding sites in the N-terminal domain of the prion protein by EPR and CD spectroscopy. Biochemistry. 2000 Nov 14; 39(45):13760-71.
Aronoff-Spencer E, Burns CS, Avdievich NI, Gerfen GJ, Peisach J, Antholine WE, Ball HL, Cohen FE, Prusiner SB, Millhauser GL. PMID: 11076515; PMCID: PMC2903970.
View in:
PubMed Mentions:
84 Fields:
Translation:
HumansCells
-
Expression of unglycosylated mutated prion protein facilitates PrP(Sc) formation in neuroblastoma cells infected with different prion strains. J Gen Virol. 2000 Oct; 81(Pt 10):2555-2563.
Korth C, Kaneko K, Prusiner SB. PMID: 10993946.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
-
Quantitative trait loci affecting prion incubation time in mice. Genomics. 2000 Oct 01; 69(1):47-53.
Stephenson DA, Chiotti K, Ebeling C, Groth D, DeArmond SJ, Prusiner SB, Carlson GA. PMID: 11013074.
View in:
PubMed Mentions:
53 Fields:
Translation:
AnimalsCells
-
Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss. J Biol Chem. 2000 Sep 01; 275(35):26834-41.
Silverman GL, Qin K, Moore RC, Yang Y, Mastrangelo P, Tremblay P, Prusiner SB, Cohen FE, Westaway D. PMID: 10842180.
View in:
PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
-
Selective neuronal vulnerability during experimental scrapie infection: insights from an ultrastructural investigation. Brain Res. 2000 Aug 25; 874(2):210-5.
Bouzamondo E, Milroy AM, Ralston HJ, Prusiner SB, DeArmond SJ. PMID: 10960606.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Structural changes in a hydrophobic domain of the prion protein induced by hydration and by ala-->Val and pro-->Leu substitutions. J Mol Biol. 2000 Jul 28; 300(5):1283-96.
Inouye H, Bond J, Baldwin MA, Ball HL, Prusiner SB, Kirschner DA. PMID: 10903869.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
-
Scrapie infectivity is independent of amyloid staining properties of the N-terminally truncated prion protein. J Struct Biol. 2000 Jun; 130(2-3):323-38.
Wille H, Prusiner SB, Cohen FE. PMID: 10940236.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
-
Mimicking dominant negative inhibition of prion replication through structure-based drug design. Proc Natl Acad Sci U S A. 2000 May 23; 97(11):6073-8.
Perrier V, Wallace AC, Kaneko K, Safar J, Prusiner SB, Cohen FE. PMID: 10823951; PMCID: PMC18560.
View in:
PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
-
Cultured cell sublines highly susceptible to prion infection. J Virol. 2000 May; 74(9):4377-86.
Bosque PJ, Prusiner SB. PMID: 10756052; PMCID: PMC111954.
View in:
PubMed Mentions:
80 Fields:
Translation:
AnimalsCells
-
Dominant-negative inhibition of prion formation diminished by deletion mutagenesis of the prion protein. J Virol. 2000 May; 74(9):4351-60.
Zulianello L, Kaneko K, Scott M, Erpel S, Han D, Cohen FE, Prusiner SB. PMID: 10756050; PMCID: PMC111952.
View in:
PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
-
Self-assembly of recombinant prion protein of 106 residues. Biochemistry. 2000 Mar 14; 39(10):2792-804.
Baskakov IV, Aagaard C, Mehlhorn I, Wille H, Groth D, Baldwin MA, Prusiner SB, Cohen FE. PMID: 10704232.
View in:
PubMed Mentions:
17 Fields:
Translation:
Cells
-
The prion domain of yeast Ure2p induces autocatalytic formation of amyloid fibers by a recombinant fusion protein. Protein Sci. 2000 Mar; 9(3):440-51.
Schlumpberger M, Wille H, Baldwin MA, Butler DA, Herskowitz I, Prusiner SB. PMID: 10752606; PMCID: PMC2144574.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
-
Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry. Protein Sci. 2000 Feb; 9(2):332-43.
Whittal RM, Ball HL, Cohen FE, Burlingame AL, Prusiner SB, Baldwin MA. PMID: 10716185; PMCID: PMC2144551.
View in:
PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
-
A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice. J Mol Biol. 2000 Jan 28; 295(4):997-1007.
Kaneko K, Ball HL, Wille H, Zhang H, Groth D, Torchia M, Tremblay P, Safar J, Prusiner SB, DeArmond SJ, Baldwin MA, Cohen FE. PMID: 10656806.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
-
Transgenic models of prion disease. Arch Virol Suppl. 2000; (16):113-24.
Scott MR, Supattapone S, Nguyen HO, DeArmond SJ, Prusiner SB. PMID: 11214913.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
-
Quantitative traits of prion strains are enciphered in the conformation of the prion protein. Arch Virol Suppl. 2000; (16):227-35.
Safar J, Cohen FE, Prusiner SB. PMID: 11214926.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
-
Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans. Proc Natl Acad Sci U S A. 1999 Dec 21; 96(26):15137-42.
Scott MR, Will R, Ironside J, Nguyen HO, Tremblay P, DeArmond SJ, Prusiner SB. PMID: 10611351; PMCID: PMC24786.
View in:
PubMed Mentions:
132 Fields:
Translation:
HumansAnimals
-
Transmissible and genetic prion diseases share a common pathway of neurodegeneration. Nature. 1999 Dec 16; 402(6763):822-6.
Hegde RS, Tremblay P, Groth D, DeArmond SJ, Prusiner SB, Lingappa VR. PMID: 10617204.
View in:
PubMed Mentions:
89 Fields:
Translation:
AnimalsCells
-
Elimination of prions by branched polyamines and implications for therapeutics. Proc Natl Acad Sci U S A. 1999 Dec 07; 96(25):14529-34.
Supattapone S, Nguyen HO, Cohen FE, Prusiner SB, Scott MR. PMID: 10588739; PMCID: PMC24470.
View in:
PubMed Mentions:
64 Fields:
Translation:
HumansAnimalsCells
-
Kinetics of prion protein accumulation in the CNS of mice with experimental scrapie. J Neuropathol Exp Neurol. 1999 Dec; 58(12):1244-9.
Tatzelt J, Groth DF, Torchia M, Prusiner SB, DeArmond SJ. PMID: 10604749.
View in:
PubMed Mentions:
11 Fields:
Translation:
Animals
-
Glycosylation differences between the normal and pathogenic prion protein isoforms. Proc Natl Acad Sci U S A. 1999 Nov 09; 96(23):13044-9.
Rudd PM, Endo T, Colominas C, Groth D, Wheeler SF, Harvey DJ, Wormald MR, Serban H, Prusiner SB, Kobata A, Dwek RA. PMID: 10557270; PMCID: PMC23897.
View in:
PubMed Mentions:
93 Fields:
Translation:
AnimalsCells
-
Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change. J Mol Biol. 1999 Nov 05; 293(4):855-63.
Kanyo ZF, Pan KM, Williamson RA, Burton DR, Prusiner SB, Fletterick RJ, Cohen FE. PMID: 10543972.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
-
Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel. J Mol Biol. 1999 Oct 01; 292(4):797-817.
Moore RC, Lee IY, Silverman GL, Harrison PM, Strome R, Heinrich C, Karunaratne A, Pasternak SH, Chishti MA, Liang Y, Mastrangelo P, Wang K, Smit AF, Katamine S, Carlson GA, Cohen FE, Prusiner SB, Melton DW, Tremblay P, Hood LE, Westaway D. PMID: 10525406.
View in:
PubMed Mentions:
149 Fields:
Translation:
AnimalsCells
-
A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination. Lab Invest. 1999 Jun; 79(6):689-97.
Nishida N, Tremblay P, Sugimoto T, Shigematsu K, Shirabe S, Petromilli C, Erpel SP, Nakaoke R, Atarashi R, Houtani T, Torchia M, Sakaguchi S, DeArmond SJ, Prusiner SB, Katamine S. PMID: 10378511.
View in:
PubMed Mentions:
73 Fields:
Translation:
AnimalsCells
-
Prion protein conformation in a patient with sporadic fatal insomnia. N Engl J Med. 1999 May 27; 340(21):1630-8.
Mastrianni JA, Nixon R, Layzer R, Telling GC, Han D, DeArmond SJ, Prusiner SB. PMID: 10341275.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
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Solution structure of Syrian hamster prion protein rPrP(90-231). Biochemistry. 1999 Apr 27; 38(17):5362-77.
Liu H, Farr-Jones S, Ulyanov NB, Llinas M, Marqusee S, Groth D, Cohen FE, Prusiner SB, James TL. PMID: 10220323.
View in:
PubMed Mentions:
59 Fields:
Translation:
AnimalsCells
-
Prion protein of 106 residues creates an artifical transmission barrier for prion replication in transgenic mice. Cell. 1999 Mar 19; 96(6):869-78.
Supattapone S, Bosque P, Muramoto T, Wille H, Aagaard C, Peretz D, Nguyen HO, Heinrich C, Torchia M, Safar J, Cohen FE, DeArmond SJ, Prusiner SB, Scott M. PMID: 10102274.
View in:
PubMed Mentions:
65 Fields:
Translation:
AnimalsCells
-
Copper binding to the prion protein: structural implications of four identical cooperative binding sites. Proc Natl Acad Sci U S A. 1999 Mar 02; 96(5):2042-7.
Viles JH, Cohen FE, Prusiner SB, Goodin DB, Wright PE, Dyson HJ. PMID: 10051591; PMCID: PMC26733.
View in:
PubMed Mentions:
111 Fields:
Translation:
Cells
-
Thermodynamics of model prions and its implications for the problem of prion protein folding. J Mol Biol. 1999 Feb 19; 286(2):593-606.
Harrison PM, Chan HS, Prusiner SB, Cohen FE. PMID: 9973573.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCells
-
Ultrastructural studies on scrapie prion protein crystals obtained from reverse micellar solutions. Biophys J. 1999 Feb; 76(2):1048-62.
Wille H, Prusiner SB. PMID: 9916037; PMCID: PMC1300055.
View in:
PubMed Mentions:
17 Fields:
Translation:
Cells
-
Prions. Proc Natl Acad Sci U S A. 1998 Nov 10; 95(23):13363-83.
Prusiner SB. PMID: 9811807; PMCID: PMC33918.
View in:
PubMed Mentions:
2057 Fields:
Translation:
HumansAnimals
-
Rapid acquisition of beta-sheet structure in the prion protein prior to multimer formation. Biol Chem. 1998 Nov; 379(11):1307-17.
Post K, Pitschke M, Schäfer O, Wille H, Appel TR, Kirsch D, Mehlhorn I, Serban H, Prusiner SB, Riesner D. PMID: 9865603.
View in:
PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
-
Mapping the prion protein using recombinant antibodies. J Virol. 1998 Nov; 72(11):9413-8.
Williamson RA, Peretz D, Pinilla C, Ball H, Bastidas RB, Rozenshteyn R, Houghten RA, Prusiner SB, Burton DR. PMID: 9765500; PMCID: PMC110372.
View in:
PubMed Mentions:
104 Fields:
Translation:
AnimalsCellsPHPublic Health
-
Doxycycline control of prion protein transgene expression modulates prion disease in mice. Proc Natl Acad Sci U S A. 1998 Oct 13; 95(21):12580-5.
Tremblay P, Meiner Z, Galou M, Heinrich C, Petromilli C, Lisse T, Cayetano J, Torchia M, Mobley W, Bujard H, DeArmond SJ, Prusiner SB. PMID: 9770528; PMCID: PMC22873.
View in:
PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
-
Eight prion strains have PrP(Sc) molecules with different conformations. Nat Med. 1998 Oct; 4(10):1157-65.
Safar J, Wille H, Itri V, Groth D, Serban H, Torchia M, Cohen FE, Prusiner SB. PMID: 9771749.
View in:
PubMed Mentions:
528 Fields:
Translation:
AnimalsCells
-
Complete genomic sequence and analysis of the prion protein gene region from three mammalian species. Genome Res. 1998 Oct; 8(10):1022-37.
Lee IY, Westaway D, Smit AF, Wang K, Seto J, Chen L, Acharya C, Ankener M, Baskin D, Cooper C, Yao H, Prusiner SB, Hood LE. PMID: 9799790.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
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The three-dimensional structure of prion protein: implications for prion disease. Biochem Soc Trans. 1998 Aug; 26(3):481-6.
Baldwin MA, James TL, Cohen FE, Prusiner SB. PMID: 9765900.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
-
The prion diseases. Brain Pathol. 1998 Jul; 8(3):499-513.
Prusiner SB. PMID: 9669700; PMCID: PMC8098303.
View in:
PubMed Mentions:
144 Fields:
Translation:
HumansAnimals
-
Prion protein selectively binds copper(II) ions. Biochemistry. 1998 May 19; 37(20):7185-93.
Stöckel J, Safar J, Wallace AC, Cohen FE, Prusiner SB. PMID: 9585530.
View in:
PubMed Mentions:
112 Fields:
Translation:
AnimalsCells
-
Neuropeptide Y: some viewpoints on a multifaceted peptide in the normal and diseased nervous system. Brain Res Brain Res Rev. 1998 May; 26(2-3):154-66.
Hökfelt T, Broberger C, Zhang X, Diez M, Kopp J, Xu Z, Landry M, Bao L, Schalling M, Koistinaho J, DeArmond SJ, Prusiner S, Gong J, Walsh JH. PMID: 9651513.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansAnimals
-
Prion protein biology. Cell. 1998 May 01; 93(3):337-48.
Prusiner SB, Scott MR, DeArmond SJ, Cohen FE. PMID: 9590169.
View in:
PubMed Mentions:
253 Fields:
Translation:
HumansAnimalsCells
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A transmembrane form of the prion protein in neurodegenerative disease. Science. 1998 Feb 06; 279(5352):827-34.
Hegde RS, Mastrianni JA, Scott MR, DeFea KA, Tremblay P, Torchia M, DeArmond SJ, Prusiner SB, Lingappa VR. PMID: 9452375.
View in:
PubMed Mentions:
208 Fields:
Translation:
HumansAnimalsCells
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Changes in the localization of brain prion proteins during scrapie infection. Neurology. 1998 Jan; 50(1):1271-80; discussion 2.
DeArmond SJ, Mobley WC, DeMott DL, Barry RA, Beckstead JH, Prusiner SB. PMID: 9443448.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Pathologic conformations of prion proteins. Annu Rev Biochem. 1998; 67:793-819.
Cohen FE, Prusiner SB. PMID: 9759504.
View in:
PubMed Mentions:
136 Fields:
Translation:
HumansCells
-
Molecular studies of prion diseases. Prog Brain Res. 1998; 117:421-34.
Safar J, Prusiner SB. PMID: 9932423.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
-
Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice. Proc Natl Acad Sci U S A. 1997 Dec 23; 94(26):14279-84.
Scott MR, Safar J, Telling G, Nguyen O, Groth D, Torchia M, Koehler R, Tremblay P, Walther D, Cohen FE, DeArmond SJ, Prusiner SB. PMID: 9405603; PMCID: PMC24939.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansAnimals
-
Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible. Proc Natl Acad Sci U S A. 1997 Dec 09; 94(25):13452-7.
Donne DG, Viles JH, Groth D, Mehlhorn I, James TL, Cohen FE, Prusiner SB, Wright PE, Dyson HJ. PMID: 9391046; PMCID: PMC28326.
View in:
PubMed Mentions:
198 Fields:
Translation:
AnimalsCells
-
Selective neuronal targeting in prion disease. Neuron. 1997 Dec; 19(6):1337-48.
DeArmond SJ, Sánchez H, Yehiely F, Qiu Y, Ninchak-Casey A, Daggett V, Camerino AP, Cayetano J, Rogers M, Groth D, Torchia M, Tremblay P, Scott MR, Cohen FE, Prusiner SB. PMID: 9427256.
View in:
PubMed Mentions:
75 Fields:
Translation:
Animals
-
Propagation of prion strains through specific conformers of the prion protein. J Virol. 1997 Dec; 71(12):9032-44.
Scott MR, Groth D, Tatzelt J, Torchia M, Tremblay P, DeArmond SJ, Prusiner SB. PMID: 9371560; PMCID: PMC230204.
View in:
PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
-
Prion protein expression in Chinese hamster ovary cells using a glutamine synthetase selection and amplification system. Protein Eng. 1997 Dec; 10(12):1465-73.
Blochberger TC, Cooper C, Peretz D, Tatzelt J, Griffith OH, Baldwin MA, Prusiner SB. PMID: 9543009.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
Marked decrease of neuropeptide Y Y2 receptor binding sites in the hippocampus in murine prion disease. Proc Natl Acad Sci U S A. 1997 Nov 25; 94(24):13267-72.
Diez M, Koistinaho J, Dearmond SJ, Groth D, Prusiner SB, Hökfelt T. PMID: 9371835; PMCID: PMC24298.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis. J Virol. 1997 Nov; 71(11):8821-31.
Schätzl HM, Laszlo L, Holtzman DM, Tatzelt J, DeArmond SJ, Weiner RI, Mobley WC, Prusiner SB. PMID: 9343242; PMCID: PMC192348.
View in:
PubMed Mentions:
103 Fields:
Translation:
AnimalsCells
-
A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform. J Mol Biol. 1997 Oct 31; 273(3):614-22.
Peretz D, Williamson RA, Matsunaga Y, Serban H, Pinilla C, Bastidas RB, Rozenshteyn R, James TL, Houghten RA, Cohen FE, Prusiner SB, Burton DR. PMID: 9356250.
View in:
PubMed Mentions:
121 Fields:
Translation:
AnimalsCells
-
Prion diseases and the BSE crisis. Science. 1997 Oct 10; 278(5336):245-51.
Prusiner SB. PMID: 9323196.
View in:
PubMed Mentions:
200 Fields:
Translation:
HumansAnimalsCells
-
Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation. Proc Natl Acad Sci U S A. 1997 Sep 16; 94(19):10069-74.
Kaneko K, Zulianello L, Scott M, Cooper CM, Wallace AC, James TL, Cohen FE, Prusiner SB. PMID: 9294164; PMCID: PMC23307.
View in:
PubMed Mentions:
168 Fields:
Translation:
HumansAnimalsCells
-
Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform. Proc Natl Acad Sci U S A. 1997 Sep 16; 94(19):10086-91.
James TL, Liu H, Ulyanov NB, Farr-Jones S, Zhang H, Donne DG, Kaneko K, Groth D, Mehlhorn I, Prusiner SB, Cohen FE. PMID: 9294167; PMCID: PMC23313.
View in:
PubMed Mentions:
136 Fields:
Translation:
HumansAnimalsCells
-
Molecular properties of complexes formed between the prion protein and synthetic peptides. J Mol Biol. 1997 Jul 25; 270(4):574-86.
Kaneko K, Wille H, Mehlhorn I, Zhang H, Ball H, Cohen FE, Baldwin MA, Prusiner SB. PMID: 9245588.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Heritable disorder resembling neuronal storage disease in mice expressing prion protein with deletion of an alpha-helix. Nat Med. 1997 Jul; 3(7):750-5.
Muramoto T, DeArmond SJ, Scott M, Telling GC, Cohen FE, Prusiner SB. PMID: 9212101.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
-
Familial Creutzfeldt-Jakob disease. Codon 200 prion disease in Libyan Jews. Medicine (Baltimore). 1997 Jul; 76(4):227-37.
Meiner Z, Gabizon R, Prusiner SB. PMID: 9279329.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
-
Kinetics and mechanism of amyloid formation by the prion protein H1 peptide as determined by time-dependent ESR. Chem Biol. 1997 May; 4(5):345-55.
Lundberg KM, Stenland CJ, Cohen FE, Prusiner SB, Millhauser GL. PMID: 9195875.
View in:
PubMed Mentions:
7 Fields:
-
N-terminally tagged prion protein supports prion propagation in transgenic mice. Protein Sci. 1997 Apr; 6(4):825-33.
Telling GC, Tremblay P, Torchia M, Dearmond SJ, Cohen FE, Prusiner SB. PMID: 9098892; PMCID: PMC2144756.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Physical studies of conformational plasticity in a recombinant prion protein. Biochemistry. 1997 Mar 25; 36(12):3543-53.
Zhang H, Stockel J, Mehlhorn I, Groth D, Baldwin MA, Prusiner SB, James TL, Cohen FE. PMID: 9132005.
View in:
PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
-
COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform. Proc Natl Acad Sci U S A. 1997 Mar 18; 94(6):2333-8.
Kaneko K, Vey M, Scott M, Pilkuhn S, Cohen FE, Prusiner SB. PMID: 9122195; PMCID: PMC20088.
View in:
PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
-
Failure to transmit disease from gray tremor mutant mice. J Virol. 1997 Mar; 71(3):2342-5.
Carlson GA, Banks S, Lund D, Reichert C, Groth D, Torchia M, Dearmond SJ, Prusiner SB. PMID: 9032370; PMCID: PMC191343.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
-
The prion folding problem. Curr Opin Struct Biol. 1997 Feb; 7(1):53-9.
Harrison PM, Bamborough P, Daggett V, Prusiner SB, Cohen FE. PMID: 9032055.
View in:
PubMed Mentions:
33 Fields:
Translation:
Cells
-
Prion protein gene variation among primates. J Mol Biol. 1997 Jan 17; 265(2):257.
Schätzl HM, Da Costa M, Taylor L, Cohen FE, Prusiner SB. PMID: 9020986.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Identification of candidate proteins binding to prion protein. Neurobiol Dis. 1997; 3(4):339-55.
Yehiely F, Bamborough P, Da Costa M, Perry BJ, Thinakaran G, Cohen FE, Carlson GA, Prusiner SB. PMID: 9173930.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
-
Genetics of prions. Annu Rev Genet. 1997; 31:139-75.
Prusiner SB, Scott MR. PMID: 9442893.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansAnimals
-
Recombinant scrapie-like prion protein of 106 amino acids is soluble. Proc Natl Acad Sci U S A. 1996 Dec 24; 93(26):15457-62.
Muramoto T, Scott M, Cohen FE, Prusiner SB. PMID: 8986833; PMCID: PMC26426.
View in:
PubMed Mentions:
72 Fields:
Translation:
Cells
-
Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity. Science. 1996 Dec 20; 274(5295):2079-82.
Telling GC, Parchi P, DeArmond SJ, Cortelli P, Montagna P, Gabizon R, Mastrianni J, Lugaresi E, Gambetti P, Prusiner SB. PMID: 8953038.
View in:
PubMed Mentions:
342 Fields:
Translation:
HumansAnimalsCells
-
Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains. Proc Natl Acad Sci U S A. 1996 Dec 10; 93(25):14945-9.
Vey M, Pilkuhn S, Wille H, Nixon R, DeArmond SJ, Smart EJ, Anderson RG, Taraboulos A, Prusiner SB. PMID: 8962161; PMCID: PMC26242.
View in:
PubMed Mentions:
147 Fields:
Translation:
AnimalsCells
-
Chemical chaperones interfere with the formation of scrapie prion protein. EMBO J. 1996 Dec 02; 15(23):6363-73.
Tatzelt J, Prusiner SB, Welch WJ. PMID: 8978663; PMCID: PMC452460.
View in:
PubMed Mentions:
68 Fields:
Translation:
AnimalsCells
-
Molecular biology and pathogenesis of prion diseases. Trends Biochem Sci. 1996 Dec; 21(12):482-7.
Prusiner SB. PMID: 9009832.
View in:
PubMed Mentions:
67 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
-
Mutation of the prion protein gene at codon 208 in familial Creutzfeldt-Jakob disease. Neurology. 1996 Nov; 47(5):1305-12.
Mastrianni JA, Iannicola C, Myers RM, DeArmond S, Prusiner SB. PMID: 8909447.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
-
Prion biology and diseases--laughing cannibals, mad cows, and scientific heresy. Med Res Rev. 1996 Sep; 16(5):487-505.
Prusiner SB. PMID: 8865151.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
-
Decreased receptor-mediated calcium response in prion-infected cells correlates with decreased membrane fluidity and IP3 release. Neurology. 1996 Sep; 47(3):741-50.
Wong K, Qiu Y, Hyun W, Nixon R, VanCleff J, Sanchez-Salazar J, Prusiner SB, DeArmond SJ. PMID: 8797473.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
-
Aberrant induction of neuropeptide Y mRNA in hippocampal CA3 pyramidal neurones in scrapie-infected mice. Neuroreport. 1996 Aug 12; 7(12):1887-92.
Diez M, Koistinaho J, DeArmond SJ, Camerino AP, Groth D, Caytano JC, Prusiner SB, Hökfelt T. PMID: 8905686.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Scrapie in mice deficient in apolipoprotein E or glial fibrillary acidic protein. Neurology. 1996 Aug; 47(2):449-53.
Tatzelt J, Maeda N, Pekny M, Yang SL, Betsholtz C, Eliasson C, Cayetano J, Camerino AP, DeArmond SJ, Prusiner SB. PMID: 8757019.
View in:
PubMed Mentions:
19 Fields:
Translation:
Animals
-
Solid-state NMR studies of the prion protein H1 fragment. Protein Sci. 1996 Aug; 5(8):1655-61.
Heller J, Kolbert AC, Larsen R, Ernst M, Bekker T, Baldwin M, Prusiner SB, Pines A, Wemmer DE. PMID: 8844854; PMCID: PMC2143492.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice. Genes Dev. 1996 Jul 15; 10(14):1736-50.
Telling GC, Haga T, Torchia M, Tremblay P, DeArmond SJ, Prusiner SB. PMID: 8698234.
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PubMed Mentions:
96 Fields:
Translation:
HumansAnimals
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Circumventing tolerance to generate autologous monoclonal antibodies to the prion protein. Proc Natl Acad Sci U S A. 1996 Jul 09; 93(14):7279-82.
Williamson RA, Peretz D, Smorodinsky N, Bastidas R, Serban H, Mehlhorn I, DeArmond SJ, Prusiner SB, Burton DR. PMID: 8692983; PMCID: PMC38974.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
-
Separation of scrapie prion infectivity from PrP amyloid polymers. J Mol Biol. 1996 Jun 21; 259(4):608-21.
Wille H, Zhang GF, Baldwin MA, Cohen FE, Prusiner SB. PMID: 8683568.
View in:
PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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High-level expression and characterization of a purified 142-residue polypeptide of the prion protein. Biochemistry. 1996 Apr 30; 35(17):5528-37.
Mehlhorn I, Groth D, Stöckel J, Moffat B, Reilly D, Yansura D, Willett WS, Baldwin M, Fletterick R, Cohen FE, Vandlen R, Henner D, Prusiner SB. PMID: 8611544.
View in:
PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
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Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus. Proc Natl Acad Sci U S A. 1996 Mar 19; 93(6):2403-7.
Lledo PM, Tremblay P, DeArmond SJ, Prusiner SB, Nicoll RA. PMID: 8637886; PMCID: PMC39809.
View in:
PubMed Mentions:
53 Fields:
Translation:
AnimalsCells
-
Disruption of prion rods generates 10-nm spherical particles having high alpha-helical content and lacking scrapie infectivity. J Virol. 1996 Mar; 70(3):1714-22.
Riesner D, Kellings K, Post K, Wille H, Serban H, Groth D, Baldwin MA, Prusiner SB. PMID: 8627692; PMCID: PMC189995.
View in:
PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Lipid composition in scrapie-infected mouse brain: prion infection increases the levels of dolichyl phosphate and ubiquinone. J Neurochem. 1996 Jan; 66(1):277-85.
Guan Z, Söderberg M, Sindelar P, Prusiner SB, Kristensson K, Dallner G. PMID: 8522965.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Structures of prion proteins and conformational models for prion diseases. Curr Top Microbiol Immunol. 1996; 207:49-67.
Huang Z, Prusiner SB, Cohen FE. PMID: 8575206.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Transgenetics of prion diseases. Curr Top Microbiol Immunol. 1996; 206:275-304.
Prusiner SB. PMID: 8608721.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
-
Prion protein amyloid: separation of scrapie infectivity from PrP polymers. Ciba Found Symp. 1996; 199:181-99; discussion 199-201.
Wille H, Baldwin MA, Cohen FE, DeArmond SJ, Prusiner SB. PMID: 8915611.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Insoluble wild-type and protease-resistant mutant prion protein in brains of patients with inherited prion disease. Nat Med. 1996 Jan; 2(1):59-64.
Gabizon R, Telling G, Meiner Z, Halimi M, Kahana I, Prusiner SB. PMID: 8564843.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Human prion diseases and neurodegeneration. Curr Top Microbiol Immunol. 1996; 207:1-17.
Prusiner SB. PMID: 8575200.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
-
Transgenetics and gene targeting in studies of prion diseases. Curr Top Microbiol Immunol. 1996; 207:95-123.
Scott MR, Telling GC, Prusiner SB. PMID: 8575209.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
-
Scrapie prions: a three-dimensional model of an infectious fragment. Fold Des. 1996; 1(1):13-9.
Huang Z, Prusiner SB, Cohen FE. PMID: 9079359.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Molecular biology and genetics of prion diseases. Cold Spring Harb Symp Quant Biol. 1996; 61:473-93.
Prusiner SB. PMID: 9246475.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
-
Abnormal plasma membrane properties and functions in prion-infected cell lines. Cold Spring Harb Symp Quant Biol. 1996; 61:531-40.
DeArmond SJ, Qiu Y, Wong K, Nixon R, Hyun W, Prusiner SB, Mobley WC. PMID: 9246479.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Transgenetics and neuropathology of prion diseases. Curr Top Microbiol Immunol. 1996; 207:125-46.
DeArmond SJ, Prusiner SB. PMID: 8575201.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Prion protein structure and scrapie replication: theoretical, spectroscopic, and genetic investigations. Cold Spring Harb Symp Quant Biol. 1996; 61:495-509.
Bamborough P, Wille H, Telling GC, Yehiely F, Prusiner SB, Cohen FE. PMID: 9246476.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform. Proc Natl Acad Sci U S A. 1995 Nov 21; 92(24):11160-4.
Kaneko K, Peretz D, Pan KM, Blochberger TC, Wille H, Gabizon R, Griffith OH, Cohen FE, Baldwin MA, Prusiner SB. PMID: 7479957; PMCID: PMC40591.
View in:
PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
-
Prion disease (PrP-A117V) presenting with ataxia instead of dementia. Neurology. 1995 Nov; 45(11):2042-50.
Mastrianni JA, Curtis MT, Oberholtzer JC, Da Costa MM, DeArmond S, Prusiner SB, Garbern JY. PMID: 7501157.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein. Cell. 1995 Oct 06; 83(1):79-90.
Telling GC, Scott M, Mastrianni J, Gabizon R, Torchia M, Cohen FE, DeArmond SJ, Prusiner SB. PMID: 7553876.
View in:
PubMed Mentions:
237 Fields:
Translation:
HumansAnimalsCells
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Scanning for mutations in the human prion protein open reading frame by temporal temperature gradient gel electrophoresis. Electrophoresis. 1995 Oct; 16(10):1851-60.
Wiese U, Wulfert M, Prusiner SB, Riesner D. PMID: 8586053.
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PubMed Mentions: Fields:
Translation:
HumansCells
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X-ray diffraction of scrapie prion rods and PrP peptides. J Mol Biol. 1995 Sep 29; 252(4):412-22.
Nguyen JT, Inouye H, Baldwin MA, Fletterick RJ, Cohen FE, Prusiner SB, Kirschner DA. PMID: 7563061.
View in:
PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
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Complete penetrance of Creutzfeldt-Jakob disease in Libyan Jews carrying the E200K mutation in the prion protein gene. Mol Med. 1995 Sep; 1(6):607-13.
Spudich S, Mastrianni JA, Wrensch M, Gabizon R, Meiner Z, Kahana I, Rosenmann H, Kahana E, Prusiner SB. PMID: 8529127; PMCID: PMC2229975.
View in:
PubMed Mentions:
30 Fields:
Translation:
Humans
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Prion protein isoforms, a convergence of biological and structural investigations. J Biol Chem. 1995 Aug 18; 270(33):19197-200.
Baldwin MA, Cohen FE, Prusiner SB. PMID: 7642588.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
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Conformational transitions in peptides containing two putative alpha-helices of the prion protein. J Mol Biol. 1995 Jul 21; 250(4):514-26.
Zhang H, Kaneko K, Nguyen JT, Livshits TL, Baldwin MA, Cohen FE, James TL, Prusiner SB. PMID: 7542350.
View in:
PubMed Mentions:
37 Fields:
Translation:
Cells
-
Molecular genetics and biophysics of prions. Uirusu. 1995 Jun; 45(1):5-42.
Prusiner SB. PMID: 7571451.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Expression and targeting of Syrian hamster prion protein induced by heat shock in transgenic Drosophila melanogaster. Mech Dev. 1995 Jun; 51(2-3):317-27.
Raeber AJ, Muramoto T, Kornberg TB, Prusiner SB. PMID: 7547477.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Theoretical studies of sequence effects on the conformational properties of a fragment of the prion protein: implications for scrapie formation. Chem Biol. 1995 May; 2(5):305-15.
Kazmirski SL, Alonso DO, Cohen FE, Prusiner SB, Daggett V. PMID: 9383432.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Prion protein peptides induce alpha-helix to beta-sheet conformational transitions. Biochemistry. 1995 Apr 04; 34(13):4186-92.
Nguyen J, Baldwin MA, Cohen FE, Prusiner SB. PMID: 7703230.
View in:
PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
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Etiology and pathogenesis of prion diseases. Am J Pathol. 1995 Apr; 146(4):785-811.
DeArmond SJ, Prusiner SB. PMID: 7717447; PMCID: PMC1869256.
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PubMed Mentions:
49 Fields:
Translation:
HumansAnimalsCells
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Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform. J Cell Biol. 1995 Apr; 129(1):121-32.
Taraboulos A, Scott M, Semenov A, Avrahami D, Laszlo L, Prusiner SB, Avraham D. PMID: 7698979; PMCID: PMC2120366.
View in:
PubMed Mentions:
179 Fields:
Translation:
AnimalsCells
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On safari with PrP: prion diseases of animals. Trends Microbiol. 1995 Apr; 3(4):141-7.
Westaway D, Carlson GA, Prusiner SB. PMID: 7613755.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Scrapie prions selectively modify the stress response in neuroblastoma cells. Proc Natl Acad Sci U S A. 1995 Mar 28; 92(7):2944-8.
Tatzelt J, Zuo J, Voellmy R, Scott M, Hartl U, Prusiner SB, Welch WJ. PMID: 7708753; PMCID: PMC42335.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Prion protein gene variation among primates. J Mol Biol. 1995 Jan 27; 245(4):362-74.
Schätzl HM, Da Costa M, Taylor L, Cohen FE, Prusiner SB. PMID: 7837269.
View in:
PubMed Mentions:
83 Fields:
Translation:
HumansAnimalsCells
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Prion protein transgenes and the neuropathology in prion diseases. Brain Pathol. 1995 Jan; 5(1):77-89.
DeArmond SJ, Prusiner SB. PMID: 7767493.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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The prion diseases. Sci Am. 1995 Jan; 272(1):48-51, 54-7.
Prusiner SB. PMID: 7824915.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimals
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Scrapie infection of transgenic mice leads to network and intrinsic dysfunction of cortical and hippocampal neurones. Neurobiol Dis. 1994 Nov; 1(1-2):25-30.
Jefferys JG, Empson RM, Whittington MA, Prusiner SB. PMID: 9216983.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals
-
Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein. Proc Natl Acad Sci U S A. 1994 Oct 11; 91(21):9936-40.
Telling GC, Scott M, Hsiao KK, Foster D, Yang SL, Torchia M, Sidle KC, Collinge J, DeArmond SJ, Prusiner SB. PMID: 7937921; PMCID: PMC44932.
View in:
PubMed Mentions:
101 Fields:
Translation:
HumansAnimalsCells
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Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein. Proc Natl Acad Sci U S A. 1994 Sep 13; 91(19):9126-30.
Hsiao KK, Groth D, Scott M, Yang SL, Serban H, Rapp D, Foster D, Torchia M, Dearmond SJ, Prusiner SB. PMID: 7916462; PMCID: PMC44760.
View in:
PubMed Mentions:
75 Fields:
Translation:
Animals
-
Neurodegeneration in humans caused by prions. West J Med. 1994 Sep; 161(3):264-72.
Prusiner SB. PMID: 7975565; PMCID: PMC1011408.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Proposed three-dimensional structure for the cellular prion protein. Proc Natl Acad Sci U S A. 1994 Jul 19; 91(15):7139-43.
Huang Z, Gabriel JM, Baldwin MA, Fletterick RJ, Prusiner SB, Cohen FE. PMID: 7913747; PMCID: PMC44354.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
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Structure and polymorphism of the mouse prion protein gene. Proc Natl Acad Sci U S A. 1994 Jul 05; 91(14):6418-22.
Westaway D, Cooper C, Turner S, Da Costa M, Carlson GA, Prusiner SB. PMID: 7912827; PMCID: PMC44213.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Determinants of carboxyl-terminal domain translocation during prion protein biogenesis. J Biol Chem. 1994 Jun 17; 269(24):16810-20.
De Fea KA, Nakahara DH, Calayag MC, Yost CS, Mirels LF, Prusiner SB, Lingappa VR. PMID: 7911469.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice. Proc Natl Acad Sci U S A. 1994 Jun 07; 91(12):5690-4.
Carlson GA, Ebeling C, Yang SL, Telling G, Torchia M, Groth D, Westaway D, DeArmond SJ, Prusiner SB. PMID: 7911243; PMCID: PMC44062.
View in:
PubMed Mentions:
69 Fields:
Translation:
Animals
-
Inherited prion diseases. Proc Natl Acad Sci U S A. 1994 May 24; 91(11):4611-4.
Prusiner SB. PMID: 8197105; PMCID: PMC43836.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
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Structural clues to prion replication. Science. 1994 Apr 22; 264(5158):530-1.
Cohen FE, Pan KM, Huang Z, Baldwin M, Fletterick RJ, Prusiner SB. PMID: 7909169.
View in:
PubMed Mentions:
101 Fields:
Translation:
AnimalsCells
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Homozygosity for prion protein alleles encoding glutamine-171 renders sheep susceptible to natural scrapie. Genes Dev. 1994 Apr 15; 8(8):959-69.
Westaway D, Zuliani V, Cooper CM, Da Costa M, Neuman S, Jenny AL, Detwiler L, Prusiner SB. PMID: 7926780.
View in:
PubMed Mentions:
68 Fields:
Translation:
AnimalsCells
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Human prion diseases. Ann Neurol. 1994 Apr; 35(4):385-95.
Prusiner SB, Hsiao KK. PMID: 8154865.
View in:
PubMed Mentions:
42 Fields:
Translation:
HumansAnimals
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Molecular biology and genetics of prion diseases. Philos Trans R Soc Lond B Biol Sci. 1994 Mar 29; 343(1306):447-63.
Prusiner SB. PMID: 7913765.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Genetics of prion diseases and prion diversity in mice. Philos Trans R Soc Lond B Biol Sci. 1994 Mar 29; 343(1306):363-9.
Carlson GA, DeArmond SJ, Torchia M, Westaway D, Prusiner SB. PMID: 7913753.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Mutation in codon 200 and polymorphism in codon 129 of the prion protein gene in Libyan Jews with Creutzfeldt-Jakob disease. Philos Trans R Soc Lond B Biol Sci. 1994 Mar 29; 343(1306):385-90.
Gabizon R, Rosenman H, Meiner Z, Kahana I, Kahana E, Shugart Y, Ott J, Prusiner SB. PMID: 7913755.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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The neuropathological phenotype in transgenic mice expressing different prion protein constructs. Philos Trans R Soc Lond B Biol Sci. 1994 Mar 29; 343(1306):415-23.
DeArmond SJ, Yang SL, Cayetano-Canlas J, Groth D, Prusiner SB. PMID: 7913760.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Nucleic acids in prion preparations: unspecific background or essential component? Philos Trans R Soc Lond B Biol Sci. 1994 Mar 29; 343(1306):425-30.
Kellings K, Prusiner SB, Riesner D. PMID: 7913761.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
Biosynthesis of the prion proteins in scrapie-infected cells in culture. Braz J Med Biol Res. 1994 Feb; 27(2):303-7.
Taraboulos A, Scott M, Semenov A, Avrahami D, Prusiner SB. PMID: 8081243.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Prion protein (PrP) is not involved in the pathogenesis of spongiform encephalopathy in zitter rats. Neurosci Lett. 1994 Jan 31; 166(2):171-4.
Gomi H, Ikeda T, Kunieda T, Itohara S, Prusiner SB, Yamanouchi K. PMID: 7909925.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins. Cell. 1994 Jan 14; 76(1):117-29.
Westaway D, DeArmond SJ, Cayetano-Canlas J, Groth D, Foster D, Yang SL, Torchia M, Carlson GA, Prusiner SB. PMID: 8287472.
View in:
PubMed Mentions:
108 Fields:
Translation:
AnimalsCells
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Detecting prion protein gene mutations by denaturing gradient gel electrophoresis. Hum Mutat. 1994; 4(1):42-50.
Fink JK, Peacock ML, Warren JT, Roses AD, Prusiner SB. PMID: 7951257.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Biology and genetics of prion diseases. Annu Rev Microbiol. 1994; 48:655-86.
Prusiner SB. PMID: 7826022.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansAnimals
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A national strategy for development of effective methods for the prevention and treatment of Alzheimer's disease and related neurodegenerative disorders. Neurobiol Aging. 1994; 15 Suppl 2:S29-32.
Prusiner SB. PMID: 7700455.
View in:
PubMed Mentions: Fields:
Translation:
Humans
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Prion diseases and neurodegeneration. Annu Rev Neurosci. 1994; 17:311-39.
Prusiner SB, DeArmond SJ. PMID: 8210178.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies. Proc Natl Acad Sci U S A. 1993 Nov 15; 90(22):10608-12.
Prusiner SB, Groth D, Serban A, Koehler R, Foster D, Torchia M, Burton D, Yang SL, DeArmond SJ. PMID: 7902565; PMCID: PMC47826.
View in:
PubMed Mentions:
147 Fields:
Translation:
AnimalsCells
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The neurochemistry of prion diseases. J Neurochem. 1993 Nov; 61(5):1589-601.
DeArmond SJ, Prusiner SB. PMID: 7901326.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Scrapie prions alter receptor-mediated calcium responses in cultured cells. Neurology. 1993 Nov; 43(11):2335-41.
Kristensson K, Feuerstein B, Taraboulos A, Hyun WC, Prusiner SB, DeArmond SJ. PMID: 8232952.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Genetic and infectious prion diseases. Arch Neurol. 1993 Nov; 50(11):1129-53.
Prusiner SB. PMID: 8105771.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansAnimals
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Transgenetics and cell biology of prion diseases: investigations of PrPSc synthesis and diversity. Br Med Bull. 1993 Oct; 49(4):873-912.
Prusiner SB. PMID: 8137134.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
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Mutation and polymorphism of the prion protein gene in Libyan Jews with Creutzfeldt-Jakob disease (CJD). Am J Hum Genet. 1993 Oct; 53(4):828-35.
Gabizon R, Rosenmann H, Meiner Z, Kahana I, Kahana E, Shugart Y, Ott J, Prusiner SB. PMID: 8105682; PMCID: PMC1682379.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Release of the cellular prion protein from cultured cells after loss of its glycoinositol phospholipid anchor. Glycobiology. 1993 Aug; 3(4):319-29.
Borchelt DR, Rogers M, Stahl N, Telling G, Prusiner SB. PMID: 7691278.
View in:
PubMed Mentions:
54 Fields:
Translation:
AnimalsCells
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Three scrapie prion isolates exhibit different accumulation patterns of the prion protein scrapie isoform. Proc Natl Acad Sci U S A. 1993 Jul 15; 90(14):6449-53.
DeArmond SJ, Yang SL, Lee A, Bowler R, Taraboulos A, Groth D, Prusiner SB. PMID: 8101989; PMCID: PMC46949.
View in:
PubMed Mentions:
34 Fields:
Translation:
Animals
-
Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes. Cell. 1993 Jun 04; 73(5):979-88.
Scott M, Groth D, Foster D, Torchia M, Yang SL, DeArmond SJ, Prusiner SB. PMID: 8098995.
View in:
PubMed Mentions:
113 Fields:
Translation:
Animals
-
Biology of prion diseases. J Acquir Immune Defic Syndr (1988). 1993 Jun; 6(6):663-5.
Prusiner SB. PMID: 8496798.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells. Proc Natl Acad Sci U S A. 1993 Apr 15; 90(8):3182-6.
Rogers M, Yehiely F, Scott M, Prusiner SB. PMID: 8475059; PMCID: PMC46263.
View in:
PubMed Mentions:
52 Fields:
Translation:
AnimalsCells
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Delimiting the location of the scrapie prion incubation time gene on chromosome 2 of the mouse. Genetics. 1993 Apr; 133(4):979-88.
Carlson GA, Ebeling C, Torchia M, Westaway D, Prusiner SB. PMID: 8462855; PMCID: PMC1205414.
View in:
PubMed Mentions:
13 Fields:
Translation:
Animals
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Attempts to restore scrapie prion infectivity after exposure to protein denaturants. Proc Natl Acad Sci U S A. 1993 Apr 01; 90(7):2793-7.
Prusiner SB, Groth D, Serban A, Stahl N, Gabizon R. PMID: 8464892; PMCID: PMC46182.
View in:
PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing. Biochemistry. 1993 Mar 02; 32(8):1991-2002.
Stahl N, Baldwin MA, Teplow DB, Hood L, Gibson BW, Burlingame AL, Prusiner SB. PMID: 8448158.
View in:
PubMed Mentions:
142 Fields:
Translation:
AnimalsCells
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Immunologic and molecular biologic studies of prion proteins in bovine spongiform encephalopathy. J Infect Dis. 1993 Mar; 167(3):602-13.
Prusiner SB, Füzi M, Scott M, Serban D, Serban H, Taraboulos A, Gabriel JM, Wells GA, Wilesmith JW, Bradley R, et al. PMID: 8440932.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Transgenetic investigations of prion diseases of humans and animals. Philos Trans R Soc Lond B Biol Sci. 1993 Feb 27; 339(1288):239-54.
Prusiner SB. PMID: 8097053.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Prions and nucleic acids: search for "residual" nucleic acids and screening for mutations in the PrP-gene. Dev Biol Stand. 1993; 80:173-81.
Riesner D, Kellings K, Wiese U, Wulfert M, Mirenda C, Prusiner SB. PMID: 8270107.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Prion encephalopathies of animals and humans. Dev Biol Stand. 1993; 80:31-44.
Prusiner SB. PMID: 8270114.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
-
Analysis of nucleic acids in purified scrapie prion preparations. Arch Virol Suppl. 1993; 7:215-25.
Kellings K, Meyer N, Mirenda C, Prusiner SB, Riesner D. PMID: 8219805.
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PubMed Mentions:
5 Fields:
Translation:
Animals
-
Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity. Proc Natl Acad Sci U S A. 1993 Jan 01; 90(1):1-5.
Gasset M, Baldwin MA, Fletterick RJ, Prusiner SB. PMID: 8419912; PMCID: PMC45587.
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PubMed Mentions:
65 Fields:
Translation:
AnimalsCells
-
Chemistry and biology of prions. Biochemistry. 1992 Dec 15; 31(49):12277-88.
Prusiner SB. PMID: 1463717.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
-
Predicted alpha-helical regions of the prion protein when synthesized as peptides form amyloid. Proc Natl Acad Sci U S A. 1992 Nov 15; 89(22):10940-4.
Gasset M, Baldwin MA, Lloyd DH, Gabriel JM, Holtzman DM, Cohen F, Fletterick R, Prusiner SB. PMID: 1438300; PMCID: PMC50458.
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PubMed Mentions:
86 Fields:
Translation:
AnimalsCells
-
Molecular cloning of a candidate chicken prion protein. Proc Natl Acad Sci U S A. 1992 Oct 01; 89(19):9097-101.
Gabriel JM, Oesch B, Kretzschmar H, Scott M, Prusiner SB. PMID: 1409608; PMCID: PMC50072.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Attempts to convert the cellular prion protein into the scrapie isoform in cell-free systems. J Virol. 1992 Oct; 66(10):6155-63.
Raeber AJ, Borchelt DR, Scott M, Prusiner SB. PMID: 1356161; PMCID: PMC283664.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Proc Natl Acad Sci U S A. 1992 Oct 01; 89(19):9349-53.
Giaccone G, Verga L, Bugiani O, Frangione B, Serban D, Prusiner SB, Farlow MR, Ghetti B, Tagliavini F. PMID: 1357663; PMCID: PMC50124.
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
-
Purification and properties of the cellular prion protein from Syrian hamster brain. Protein Sci. 1992 Oct; 1(10):1343-52.
Pan KM, Stahl N, Prusiner SB. PMID: 1363897; PMCID: PMC2142104.
View in:
PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
-
Natural and experimental prion diseases of humans and animals. Curr Opin Neurobiol. 1992 Oct; 2(5):638-47.
Prusiner SB. PMID: 1422120.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
-
Molecular cloning of a mink prion protein gene. J Gen Virol. 1992 Oct; 73 ( Pt 10):2757-61.
Kretzschmar HA, Neumann M, Riethmüller G, Prusiner SB. PMID: 1383401.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Regional mapping of prion proteins in brain. Proc Natl Acad Sci U S A. 1992 Aug 15; 89(16):7620-4.
Taraboulos A, Jendroska K, Serban D, Yang SL, DeArmond SJ, Prusiner SB. PMID: 1354357; PMCID: PMC49762.
View in:
PubMed Mentions:
115 Fields:
Translation:
HumansAnimals
-
Evidence for synthesis of scrapie prion proteins in the endocytic pathway. J Biol Chem. 1992 Aug 15; 267(23):16188-99.
Borchelt DR, Taraboulos A, Prusiner SB. PMID: 1353761.
View in:
PubMed Mentions:
160 Fields:
Translation:
AnimalsCells
-
Chimeric prion protein expression in cultured cells and transgenic mice. Protein Sci. 1992 Aug; 1(8):986-97.
Scott MR, Köhler R, Foster D, Prusiner SB. PMID: 1338978; PMCID: PMC2142161.
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PubMed Mentions:
95 Fields:
Translation:
AnimalsCells
-
Synthesis and trafficking of prion proteins in cultured cells. Mol Biol Cell. 1992 Aug; 3(8):851-63.
Taraboulos A, Raeber AJ, Borchelt DR, Serban D, Prusiner SB. PMID: 1356522; PMCID: PMC275644.
View in:
PubMed Mentions:
96 Fields:
Translation:
AnimalsCells
-
Replication of distinct scrapie prion isolates is region specific in brains of transgenic mice and hamsters. Genes Dev. 1992 Jul; 6(7):1213-28.
Hecker R, Taraboulos A, Scott M, Pan KM, Yang SL, Torchia M, Jendroska K, DeArmond SJ, Prusiner SB. PMID: 1628828.
View in:
PubMed Mentions:
80 Fields:
Translation:
AnimalsCells
-
Presence of prion protein in peripheral tissues of Libyan Jews with Creutzfeldt-Jakob disease. Neurology. 1992 Jul; 42(7):1355-60.
Meiner Z, Halimi M, Polakiewicz RD, Prusiner SB, Gabizon R. PMID: 1352391.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
-
Glycosylinositol phospholipid anchors of the scrapie and cellular prion proteins contain sialic acid. Biochemistry. 1992 Jun 02; 31(21):5043-53.
Stahl N, Baldwin MA, Hecker R, Pan KM, Burlingame AL, Prusiner SB. PMID: 1350920.
View in:
PubMed Mentions:
89 Fields:
Translation:
Cells
-
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature. 1992 Apr 16; 356(6370):577-82.
Büeler H, Fischer M, Lang Y, Bluethmann H, Lipp HP, DeArmond SJ, Prusiner SB, Aguet M, Weissmann C. PMID: 1373228.
View in:
PubMed Mentions:
544 Fields:
Translation:
AnimalsCells
-
Further analysis of nucleic acids in purified scrapie prion preparations by improved return refocusing gel electrophoresis. J Gen Virol. 1992 Apr; 73 ( Pt 4):1025-9.
Kellings K, Meyer N, Mirenda C, Prusiner SB, Riesner D. PMID: 1353106.
View in:
PubMed Mentions:
22 Fields:
Translation:
Animals
-
Linkage of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease to the prion protein gene. Nat Genet. 1992 Apr; 1(1):64-7.
Dlouhy SR, Hsiao K, Farlow MR, Foroud T, Conneally PM, Johnson P, Prusiner SB, Hodes ME, Ghetti B. PMID: 1363809.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansCells
-
Prion protein mutation at codon 102 in an Italian family with Gerstmann-Sträussler-Scheinker syndrome. Neurology. 1992 Apr; 42(4):809-10.
Kretzschmar HA, Kufer P, Riethmüller G, DeArmond S, Prusiner SB, Schiffer D. PMID: 1348851.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
-
Mutant prion proteins in Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles. Nat Genet. 1992 Apr; 1(1):68-71.
Hsiao K, Dlouhy SR, Farlow MR, Cass C, Da Costa M, Conneally PM, Hodes ME, Ghetti B, Prusiner SB. PMID: 1363810.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansCells
-
Molecular biology and genetics of neurodegenerative diseases caused by prions. Adv Virus Res. 1992; 41:241-80.
Prusiner SB. PMID: 1575084.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
-
Ultrastructural localization of scrapie prion proteins in cytoplasmic vesicles of infected cultured cells. Lab Invest. 1991 Dec; 65(6):622-30.
McKinley MP, Taraboulos A, Kenaga L, Serban D, Stieber A, DeArmond SJ, Prusiner SB, Gonatas N. PMID: 1684401.
View in:
PubMed Mentions:
75 Fields:
Translation:
AnimalsCells
-
Epitope mapping of the Syrian hamster prion protein utilizing chimeric and mutant genes in a vaccinia virus expression system. J Immunol. 1991 Nov 15; 147(10):3568-74.
Rogers M, Serban D, Gyuris T, Scott M, Torchia T, Prusiner SB. PMID: 1719082.
View in:
PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
-
Prions and prion proteins. FASEB J. 1991 Oct; 5(13):2799-807.
Stahl N, Prusiner SB. PMID: 1916104.
View in:
PubMed Mentions:
33 Fields:
Translation:
Cells
-
Electrospray mass spectrometry of the glycosylinositol phospholipid of the scrapie prion protein. Cell Biol Int Rep. 1991 Sep; 15(9):853-62.
Stahl N, Baldwin MA, Prusiner SB. PMID: 1686992.
View in:
PubMed Mentions:
7 Fields:
Translation:
Cells
-
Proteinase-resistant prion protein accumulation in Syrian hamster brain correlates with regional pathology and scrapie infectivity. Neurology. 1991 Sep; 41(9):1482-90.
Jendroska K, Heinzel FP, Torchia M, Stowring L, Kretzschmar HA, Kon A, Stern A, Prusiner SB, DeArmond SJ. PMID: 1679911.
View in:
PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
-
Molecular biology and pathology of scrapie and the prion diseases of humans. Brain Pathol. 1991 Jul; 1(4):297-310.
Prusiner SB, DeArmond SJ. PMID: 1669719.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimals
-
Molecular biology of prion diseases. Science. 1991 Jun 14; 252(5012):1515-22.
Prusiner SB. PMID: 1675487.
View in:
PubMed Mentions:
534 Fields:
Translation:
HumansAnimals
-
Infectious and genetic manifestations of prion diseases. Mol Plant Microbe Interact. 1991 May-Jun; 4(3):226-33.
Prusiner SB, Westaway D. PMID: 1932814.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
-
A prion protein variant in a family with the telencephalic form of Gerstmann-Sträussler-Scheinker syndrome. Neurology. 1991 May; 41(5):681-4.
Hsiao KK, Cass C, Schellenberg GD, Bird T, Devine-Gage E, Wisniewski H, Prusiner SB. PMID: 1674116.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansCells
-
Mutation of the prion protein in Libyan Jews with Creutzfeldt-Jakob disease. N Engl J Med. 1991 Apr 18; 324(16):1091-7.
Hsiao K, Meiner Z, Kahana E, Cass C, Kahana I, Avrahami D, Scarlato G, Abramsky O, Prusiner SB, Gabizon R. PMID: 2008182.
View in:
PubMed Mentions:
75 Fields:
Translation:
HumansCells
-
Molecular biology and genetics of prions--implications for sheep scrapie, "mad cows" and the BSE epidemic. Historical background. Cornell Vet. 1991 Apr; 81(2):85-101.
Prusiner SB, Torchia M, Westaway D. PMID: 2029844.
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PubMed Mentions:
1 Fields:
Translation:
Animals
-
Scrapie prion rod formation in vitro requires both detergent extraction and limited proteolysis. J Virol. 1991 Mar; 65(3):1340-51.
McKinley MP, Meyer RK, Kenaga L, Rahbar F, Cotter R, Serban A, Prusiner SB. PMID: 1704926; PMCID: PMC239910.
View in:
PubMed Mentions:
80 Fields:
Translation:
AnimalsCells
-
Amyloid protein of Gerstmann-Sträussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58. EMBO J. 1991 Mar; 10(3):513-9.
Tagliavini F, Prelli F, Ghiso J, Bugiani O, Serban D, Prusiner SB, Farlow MR, Ghetti B, Frangione B. PMID: 1672107; PMCID: PMC452678.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
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Genetics of prion infections. Trends Genet. 1991 Feb; 7(2):61-5.
Carlson GA, Hsiao K, Oesch B, Westaway D, Prusiner SB. PMID: 1903568.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
-
Ultrastructural studies of prions. Curr Top Microbiol Immunol. 1991; 172:75-91.
McKinley MP, Prusiner SB. PMID: 1725771.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Molecular biology and transgenetics of prion diseases. Crit Rev Biochem Mol Biol. 1991; 26(5-6):397-438.
Prusiner SB. PMID: 1684745.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
-
Search for a putative scrapie genome in purified prion fractions reveals a paucity of nucleic acids. J Gen Virol. 1991 Jan; 72 ( Pt 1):37-49.
Meyer N, Rosenbaum V, Schmidt B, Gilles K, Mirenda C, Groth D, Prusiner SB, Riesner D. PMID: 1899270.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
-
Molecular biology of prions causing infectious and genetic encephalopathies of humans as well as scrapie of sheep and BSE of cattle. Dev Biol Stand. 1991; 75:55-74.
Prusiner SB. PMID: 1686599.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
-
Prion biology and diseases. Harvey Lect. 1991-1992; 87:85-114.
Prusiner SB. PMID: 1670551.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
-
Novel properties and biology of scrapie prions. Curr Top Microbiol Immunol. 1991; 172:233-57.
Prusiner SB. PMID: 1687382.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Molecular genetics and transgenic model of Gertsmann-Sträussler-Scheinker disease. Alzheimer Dis Assoc Disord. 1991; 5(3):155-62.
Hsiao K, Prusiner SB. PMID: 1685324.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
-
Spontaneous neurodegeneration in transgenic mice with prion protein codon 101 proline----leucine substitution. Ann N Y Acad Sci. 1991; 640:166-70.
Hsiao K, Scott M, Foster D, DeArmond SJ, Groth D, Serban H, Prusiner SB. PMID: 1685642.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Prion protein genes: evolutionary and functional aspects. Curr Top Microbiol Immunol. 1991; 172:109-24.
Oesch B, Westaway D, Prusiner SB. PMID: 1687379.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Acceleration of scrapie in trisomy 16----diploid aggregation chimeras. Ann Neurol. 1991 Jan; 29(1):95-7.
Epstein CJ, Foster DB, DeArmond SJ, Prusiner SB. PMID: 1996884.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Spontaneous neurodegeneration in transgenic mice with mutant prion protein. Science. 1990 Dec 14; 250(4987):1587-90.
Hsiao KK, Scott M, Foster D, Groth DF, DeArmond SJ, Prusiner SB. PMID: 1980379.
View in:
PubMed Mentions:
143 Fields:
Translation:
AnimalsCells
-
Inherited human prion diseases. Neurology. 1990 Dec; 40(12):1820-7.
Hsiao K, Prusiner SB. PMID: 2247227.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansAnimals
-
Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication. Cell. 1990 Nov 16; 63(4):673-86.
Prusiner SB, Scott M, Foster D, Pan KM, Groth D, Mirenda C, Torchia M, Yang SL, Serban D, Carlson GA, et al. PMID: 1977523.
View in:
PubMed Mentions:
305 Fields:
Translation:
AnimalsCells
-
Permethylation and tandem mass spectrometry of oligosaccharides having free hexosamine: analysis of the glycoinositol phospholipid anchor glycan from the scrapie prion protein. Anal Biochem. 1990 Nov 15; 191(1):174-82.
Baldwin MA, Stahl N, Reinders LG, Gibson BW, Prusiner SB, Burlingame AL. PMID: 1981823.
View in:
PubMed Mentions:
20 Fields:
Translation:
Cells
-
Immunolocalization of heparan sulfate proteoglycans to the prion protein amyloid plaques of Gerstmann-Straussler syndrome, Creutzfeldt-Jakob disease and scrapie. Lab Invest. 1990 Nov; 63(5):601-11.
Snow AD, Wight TN, Nochlin D, Koike Y, Kimata K, DeArmond SJ, Prusiner SB. PMID: 1977959.
View in:
PubMed Mentions:
42 Fields:
Translation:
HumansAnimalsCells
-
Acquisition of protease resistance by prion proteins in scrapie-infected cells does not require asparagine-linked glycosylation. Proc Natl Acad Sci U S A. 1990 Nov; 87(21):8262-6.
Taraboulos A, Rogers M, Borchelt DR, McKinley MP, Scott M, Serban D, Prusiner SB. PMID: 1978322; PMCID: PMC54935.
View in:
PubMed Mentions:
46 Fields:
Translation:
Cells
-
Novel structure and genetics of prions causing neurodegeneration in humans and animals. Biologicals. 1990 Oct; 18(4):247-62.
Prusiner SB. PMID: 1981006.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
-
Identification of glycoinositol phospholipid linked and truncated forms of the scrapie prion protein. Biochemistry. 1990 Sep 25; 29(38):8879-84.
Stahl N, Baldwin MA, Burlingame AL, Prusiner SB. PMID: 1980209.
View in:
PubMed Mentions:
58 Fields:
Translation:
AnimalsCells
-
Intracellular accumulation of the cellular prion protein after mutagenesis of its Asn-linked glycosylation sites. Glycobiology. 1990 Sep; 1(1):101-9.
Rogers M, Taraboulos A, Scott M, Groth D, Prusiner SB. PMID: 1983782.
View in:
PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
-
Link between scrapie and BSE? Nature. 1990 Jul 12; 346(6280):113.
Westaway D, Prusiner SB. PMID: 2366871.
View in:
PubMed Mentions: Fields:
Translation:
Animals
-
Identification of cellular proteins binding to the scrapie prion protein. Biochemistry. 1990 Jun 19; 29(24):5848-55.
Oesch B, Teplow DB, Stahl N, Serban D, Hood LE, Prusiner SB. PMID: 1974464.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Differential release of cellular and scrapie prion proteins from cellular membranes by phosphatidylinositol-specific phospholipase C. Biochemistry. 1990 Jun 05; 29(22):5405-12.
Stahl N, Borchelt DR, Prusiner SB. PMID: 1974460.
View in:
PubMed Mentions:
61 Fields:
Translation:
AnimalsCells
-
Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells. J Cell Biol. 1990 Jun; 110(6):2117-32.
Taraboulos A, Serban D, Prusiner SB. PMID: 1693623; PMCID: PMC2116143.
View in:
PubMed Mentions:
85 Fields:
Translation:
AnimalsCells
-
Unusual topogenic sequence directs prion protein biogenesis. Science. 1990 Apr 13; 248(4952):226-9.
Lopez CD, Yost CS, Prusiner SB, Myers RM, Lingappa VR. PMID: 1970195.
View in:
PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
-
Three hamster species with different scrapie incubation times and neuropathological features encode distinct prion proteins. Mol Cell Biol. 1990 Mar; 10(3):1153-63.
Lowenstein DH, Butler DA, Westaway D, McKinley MP, DeArmond SJ, Prusiner SB. PMID: 2406562; PMCID: PMC360985.
View in:
PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
DNA length polymorphism 5' to the myelin basic protein gene is associated with multiple sclerosis. Ann Neurol. 1990 Mar; 27(3):291-7.
Boylan KB, Takahashi N, Paty DW, Sadovnick AD, Diamond M, Hood LE, Prusiner SB. PMID: 1691612.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells. J Cell Biol. 1990 Mar; 110(3):743-52.
Borchelt DR, Scott M, Taraboulos A, Stahl N, Prusiner SB. PMID: 1968466; PMCID: PMC2116048.
View in:
PubMed Mentions:
131 Fields:
Translation:
AnimalsCells
-
Prion liposomes. Biochem J. 1990 Feb 15; 266(1):1-14.
Gabizon R, Prusiner SB. PMID: 1968741; PMCID: PMC1131089.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
Non-hydrophobic extracytoplasmic determinant of stop transfer in the prion protein. Nature. 1990 Feb 15; 343(6259):669-72.
Yost CS, Lopez CD, Prusiner SB, Myers RM, Lingappa VR. PMID: 1968226.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
-
Repetitive DNA (TGGA)n 5' to the human myelin basic protein gene: a new form of oligonucleotide repetitive sequence showing length polymorphism. Genomics. 1990 Jan; 6(1):16-22.
Boylan KB, Ayres TM, Popko B, Takahashi N, Hood LE, Prusiner SB. PMID: 1689270.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
-
Nerve growth factor induces gene expression of the prion protein and beta-amyloid protein precursor in the developing hamster central nervous system. Prog Brain Res. 1990; 86:227-38.
McKinley MP, Longo FM, Valletta JS, Rahbar F, Neve RL, Prusiner SB, Mobley WC. PMID: 1982367.
View in:
PubMed Mentions: Fields:
Translation:
Animals
-
Prion diseases of the central nervous system. Monogr Pathol. 1990; (32):86-122.
Prusiner SB, DeArmond SJ. PMID: 2192281.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
-
Rapid detection of Creutzfeldt-Jakob disease and scrapie prion proteins. Neurology. 1990 Jan; 40(1):110-7.
Serban D, Taraboulos A, DeArmond SJ, Prusiner SB. PMID: 1967489.
View in:
PubMed Mentions:
72 Fields:
Translation:
HumansAnimals
-
Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques. Cell. 1989 Dec 01; 59(5):847-57.
Scott M, Foster D, Mirenda C, Serban D, Coufal F, Wälchli M, Torchia M, Groth D, Carlson G, DeArmond SJ, Westaway D, Prusiner SB. PMID: 2574076.
View in:
PubMed Mentions:
219 Fields:
Translation:
AnimalsCells
-
Diversity of oligosaccharide structures linked to asparagines of the scrapie prion protein. Biochemistry. 1989 Oct 17; 28(21):8380-8.
Endo T, Groth D, Prusiner SB, Kobata A. PMID: 2574992.
View in:
PubMed Mentions:
86 Fields:
Translation:
AnimalsCells
-
Primary structure of prion protein may modify scrapie isolate properties. Proc Natl Acad Sci U S A. 1989 Oct; 86(19):7475-9.
Carlson GA, Westaway D, DeArmond SJ, Peterson-Torchia M, Prusiner SB. PMID: 2798418; PMCID: PMC298087.
View in:
PubMed Mentions:
21 Fields:
Translation:
Animals
-
Acceleration of scrapie in neonatal Syrian hamsters. Neurology. 1989 Oct; 39(10):1319-24.
McKinley MP, DeArmond SJ, Torchia M, Mobley WC, Prusiner SB. PMID: 2507957.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals
-
Unraveling prion diseases through molecular genetics. Trends Neurosci. 1989 Jun; 12(6):221-7.
Westaway D, Carlson GA, Prusiner SB. PMID: 2473558.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansAnimals
-
Creutzfeldt-Jakob disease and scrapie prions. Alzheimer Dis Assoc Disord. 1989 Spring-Summer; 3(1-2):52-78.
Prusiner SB. PMID: 2568118.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome. Nature. 1989 Mar 23; 338(6213):342-5.
Hsiao K, Baker HF, Crow TJ, Poulter M, Owen F, Terwilliger JD, Westaway D, Ott J, Prusiner SB. PMID: 2564168.
View in:
PubMed Mentions:
204 Fields:
Translation:
HumansCells
-
Insertion in prion protein gene in familial Creutzfeldt-Jakob disease. Lancet. 1989 Jan 07; 1(8628):51-2.
Owen F, Poulter M, Lofthouse R, Collinge J, Crow TJ, Risby D, Baker HF, Ridley RM, Hsiao K, Prusiner SB. PMID: 2563037.
View in:
PubMed Mentions:
66 Fields:
Translation:
HumansCells
-
Sulfated glycosaminoglycans in amyloid plaques of prion diseases. Acta Neuropathol. 1989; 77(4):337-42.
Snow AD, Kisilevsky R, Willmer J, Prusiner SB, DeArmond SJ. PMID: 2523631.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansAnimals
-
Immunoaffinity purification and neutralization of scrapie prions. Prog Clin Biol Res. 1989; 317:583-600.
Gabizon R, McKinley MP, Groth D, Westaway D, DeArmond SJ, Carlson GA, Prusiner SB. PMID: 2574871.
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PubMed Mentions: Fields:
Translation:
Animals
-
PrPSc in scrapie-infected hamster brain is spatially and temporally related to histopathology and infectivity titer. Prog Clin Biol Res. 1989; 317:601-18.
De Armond SJ, Gonzales M, Mobley WC, Kon AA, Stern A, Prusiner H, Prusiner SB. PMID: 2574872.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
-
Scrapie prions. Annu Rev Microbiol. 1989; 43:345-74.
Prusiner SB. PMID: 2572197.
View in:
PubMed Mentions:
71 Fields:
Translation:
HumansAnimalsCells
-
Nerve growth factor increases mRNA levels for the prion protein and the beta-amyloid protein precursor in developing hamster brain. Proc Natl Acad Sci U S A. 1988 Dec; 85(24):9811-5.
Mobley WC, Neve RL, Prusiner SB, McKinley MP. PMID: 2904679; PMCID: PMC282871.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimals
-
Genetics and polymorphism of the mouse prion gene complex: control of scrapie incubation time. Mol Cell Biol. 1988 Dec; 8(12):5528-40.
Carlson GA, Goodman PA, Lovett M, Taylor BA, Marshall ST, Peterson-Torchia M, Westaway D, Prusiner SB. PMID: 3149717; PMCID: PMC365657.
View in:
PubMed Mentions:
64 Fields:
Translation:
Animals
-
CNS amyloid proteins in neurodegenerative diseases. Neurology. 1988 Oct; 38(10):1534-40.
Roberts GW, Lofthouse R, Allsop D, Landon M, Kidd M, Prusiner SB, Crow TJ. PMID: 2901696.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
-
Immunoaffinity purification and neutralization of scrapie prion infectivity. Proc Natl Acad Sci U S A. 1988 Sep; 85(18):6617-21.
Gabizon R, McKinley MP, Groth D, Prusiner SB. PMID: 3137571; PMCID: PMC282028.
View in:
PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
-
Purification and properties of the cellular and scrapie hamster prion proteins. Eur J Biochem. 1988 Sep 01; 176(1):21-30.
Turk E, Teplow DB, Hood LE, Prusiner SB. PMID: 3138115.
View in:
PubMed Mentions:
94 Fields:
Translation:
AnimalsCells
-
Scrapie prion liposomes and rods exhibit target sizes of 55,000 Da. Virology. 1988 Jun; 164(2):537-41.
Bellinger-Kawahara CG, Kempner E, Groth D, Gabizon R, Prusiner SB. PMID: 3130718.
View in:
PubMed Mentions:
40 Fields:
Translation:
Animals
-
Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins. J Virol. 1988 May; 62(5):1558-64.
Butler DA, Scott MR, Bockman JM, Borchelt DR, Taraboulos A, Hsiao KK, Kingsbury DT, Prusiner SB. PMID: 3282080; PMCID: PMC253182.
View in:
PubMed Mentions:
137 Fields:
Translation:
AnimalsCells
-
Properties of scrapie prion protein liposomes. J Biol Chem. 1988 Apr 05; 263(10):4950-5.
Gabizon R, McKinley MP, Groth DF, Kenaga L, Prusiner SB. PMID: 3350818.
View in:
PubMed Mentions:
25 Fields:
Translation:
Animals
-
Prion protein gene expression in cultured cells. Protein Eng. 1988 Apr; 2(1):69-76.
Scott MR, Butler DA, Bredesen DE, Wälchli M, Hsiao KK, Prusiner SB. PMID: 2908139.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
-
Characterization of prion proteins with monospecific antisera to synthetic peptides. J Immunol. 1988 Feb 15; 140(4):1188-93.
Barry RA, Vincent MT, Kent SB, Hood LE, Prusiner SB. PMID: 3125249.
View in:
PubMed Mentions:
17 Fields:
Translation:
Animals
-
Search for a scrapie-specific nucleic acid: a progress report. Ciba Found Symp. 1988; 135:209-23.
Oesch B, Groth DF, Prusiner SB, Weissmann C. PMID: 3137001.
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PubMed Mentions:
15 Fields:
Translation:
Animals
-
Novel mechanisms of degeneration of the central nervous system--prion structure and biology. Ciba Found Symp. 1988; 135:239-60.
Prusiner SB, Stahl N, DeArmond SJ. PMID: 2900720.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
-
Developmental regulation of prion protein mRNA in brain. Ciba Found Symp. 1988; 135:101-16.
McKinley MP, Lingappa VR, Prusiner SB. PMID: 2900716.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
-
Molecular structure, biology, and genetics of prions. Adv Virus Res. 1988; 35:83-136.
Prusiner SB. PMID: 2906782.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
-
Properties of scrapie prion proteins in liposomes and amyloid rods. Ciba Found Symp. 1988; 135:182-96.
Gabizon R, McKinley MP, Prusiner SB. PMID: 2900719.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
-
Genetic control of prion incubation period in mice. Ciba Found Symp. 1988; 135:84-99.
Carlson GA, Westaway D, Goodman PA, Peterson M, Marshall ST, Prusiner SB. PMID: 2900721.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
-
Prions and neurodegenerative diseases. N Engl J Med. 1987 Dec 17; 317(25):1571-81.
Prusiner SB. PMID: 3317055.
View in:
PubMed Mentions:
35 Fields:
Translation:
Humans
-
Evidence for a secretory form of the cellular prion protein. Biochemistry. 1987 Dec 15; 26(25):8110-5.
Hay B, Prusiner SB, Lingappa VR. PMID: 3126796.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
-
Immuno-gold localization of prion filaments in scrapie-infected hamster brains. Lab Invest. 1987 Dec; 57(6):646-56.
Wiley CA, Burrola PG, Buchmeier MJ, Wooddell MK, Barry RA, Prusiner SB, Lampert PW. PMID: 2891874.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
-
The burden of proof in linking AIDS to scrapie. Nature. 1987 Dec 10-16; 330(6148):525-6.
Braun MJ, Gonda MA, George DG, Bazan JF, Fletterick RJ, Prusiner SB. PMID: 2891035.
View in:
PubMed Mentions:
1 Fields:
Translation:
Cells
-
Distinct prion proteins in short and long scrapie incubation period mice. Cell. 1987 Nov 20; 51(4):651-62.
Westaway D, Goodman PA, Mirenda CA, McKinley MP, Carlson GA, Prusiner SB. PMID: 2890436.
View in:
PubMed Mentions:
147 Fields:
Translation:
AnimalsCells
-
Scrapie prion protein contains a phosphatidylinositol glycolipid. Cell. 1987 Oct 23; 51(2):229-40.
Stahl N, Borchelt DR, Hsiao K, Prusiner SB. PMID: 2444340.
View in:
PubMed Mentions:
326 Fields:
Translation:
AnimalsCells
-
Purified scrapie prions resist inactivation by procedures that hydrolyze, modify, or shear nucleic acids. Virology. 1987 Sep; 160(1):271-4.
Bellinger-Kawahara C, Diener TO, McKinley MP, Groth DF, Smith DR, Prusiner SB. PMID: 3114950.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
-
Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids. Lab Invest. 1987 Aug; 57(2):230-6.
Kitamoto T, Ogomori K, Tateishi J, Prusiner SB. PMID: 2441141.
View in:
PubMed Mentions:
160 Fields:
Translation:
HumansAnimals
-
Changes in the localization of brain prion proteins during scrapie infection. Neurology. 1987 Aug; 37(8):1271-80.
DeArmond SJ, Mobley WC, DeMott DL, Barry RA, Beckstead JH, Prusiner SB. PMID: 3112607.
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PubMed Mentions:
59 Fields:
Translation:
AnimalsCells
-
Scrapie infection diminishes spines and increases varicosities of dendrites in hamsters: a quantitative Golgi analysis. J Neuropathol Exp Neurol. 1987 Jul; 46(4):461-73.
Hogan RN, Baringer JR, Prusiner SB. PMID: 3598605.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Purified prion proteins and scrapie infectivity copartition into liposomes. Proc Natl Acad Sci U S A. 1987 Jun; 84(12):4017-21.
Gabizon R, McKinley MP, Prusiner SB. PMID: 3108886; PMCID: PMC305012.
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PubMed Mentions:
63 Fields:
Translation:
AnimalsCells
-
Immunoblotting of Creutzfeldt-Jakob disease prion proteins: host species-specific epitopes. Ann Neurol. 1987 Jun; 21(6):589-95.
Bockman JM, Prusiner SB, Tateishi J, Kingsbury DT. PMID: 3300520.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Developmental expression of prion protein gene in brain. Dev Biol. 1987 May; 121(1):105-10.
McKinley MP, Hay B, Lingappa VR, Lieberburg I, Prusiner SB. PMID: 3569656.
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PubMed Mentions:
18 Fields:
Translation:
Animals
-
DNA length polymorphism located 5' to the human myelin basic protein gene. Am J Hum Genet. 1987 May; 40(5):387-400.
Boylan KB, Takahashi N, Diamond M, Hood LE, Prusiner SB. PMID: 2437796; PMCID: PMC1684138.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Prions causing nervous system degeneration. Lab Invest. 1987 Apr; 56(4):349-63.
Prusiner SB, DeArmond SJ. PMID: 2882063.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
-
Prion diseases and central nervous system degeneration. Clin Res. 1987 Apr; 35(3):177-91.
Prusiner SB. PMID: 3552382.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
AIDS virus and scrapie protein genes. Nature. 1987 Feb 12-18; 325(6105):581.
Fernando Bazan J, Fletterick RJ, Prusiner SB. PMID: 3100963.
View in:
PubMed Mentions:
2 Fields:
Translation:
Cells
-
Biogenesis and transmembrane orientation of the cellular isoform of the scrapie prion protein [published errratum appears in Mol Cell Biol 1987 May;7(5):2035]. Mol Cell Biol. 1987 Feb; 7(2):914-20.
Hay B, Barry RA, Lieberburg I, Prusiner SB, Lingappa VR. PMID: 3547085; PMCID: PMC365150.
View in:
PubMed Mentions:
29 Fields:
Translation:
Cells
-
Predicted secondary structure and membrane topology of the scrapie prion protein. Protein Eng. 1987 Feb-Mar; 1(2):125-35.
Bazan JF, Fletterick RJ, McKinley MP, Prusiner SB. PMID: 2907134.
View in:
PubMed Mentions:
14 Fields:
Translation:
Cells
-
Purified scrapie prions resist inactivation by UV irradiation. J Virol. 1987 Jan; 61(1):159-66.
Bellinger-Kawahara C, Cleaver JE, Diener TO, Prusiner SB. PMID: 3097336; PMCID: PMC255227.
View in:
PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
-
On the biology of prions. Acta Neuropathol. 1987; 72(4):299-314.
Prusiner SB, Gabizon R, McKinley MP. PMID: 3554880.
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PubMed Mentions:
7 Fields:
Translation:
Humans
-
Prions causing degenerative neurological diseases. Annu Rev Med. 1987; 38:381-98.
Prusiner SB. PMID: 3555303.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimals
-
Prions are novel infectious pathogens causing scrapie and Creutzfeldt-Jakob disease. Bioessays. 1986 Dec; 5(6):281-6.
Prusiner SB. PMID: 3551942.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimals
-
Prion-protein immunoreactivity in human transmissible dementias. N Engl J Med. 1986 Nov 06; 315(19):1231-3.
Roberts GW, Lofthouse R, Brown R, Crow TJ, Barry RA, Prusiner SB. PMID: 3531867.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansAnimals
-
Vasoactive intestinal peptide stimulates cyclic AMP metabolism in choroid plexus epithelial cells. Brain Res. 1986 Oct 01; 384(1):138-44.
Crook RB, Prusiner SB. PMID: 3024776.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
-
Monoclonal antibodies to the cellular and scrapie prion proteins. J Infect Dis. 1986 Sep; 154(3):518-21.
Barry RA, Prusiner SB. PMID: 3090160.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
-
Linkage of prion protein and scrapie incubation time genes. Cell. 1986 Aug 15; 46(4):503-11.
Carlson GA, Kingsbury DT, Goodman PA, Coleman S, Marshall ST, DeArmond S, Westaway D, Prusiner SB. PMID: 3015416.
View in:
PubMed Mentions:
139 Fields:
Translation:
Animals
-
Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene. Cell. 1986 Aug 01; 46(3):417-28.
Basler K, Oesch B, Scott M, Westaway D, Wälchli M, Groth DF, McKinley MP, Prusiner SB, Weissmann C. PMID: 2873895.
View in:
PubMed Mentions:
215 Fields:
Translation:
AnimalsCells
-
Amyloid plaques in Creutzfeldt-Jakob disease stain with prion protein antibodies. Ann Neurol. 1986 Aug; 20(2):204-8.
Kitamoto T, Tateishi J, Tashima T, Takeshita I, Barry RA, DeArmond SJ, Prusiner SB. PMID: 3092727.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansAnimals
-
Molecular cloning of a human prion protein cDNA. DNA. 1986 Aug; 5(4):315-24.
Kretzschmar HA, Stowring LE, Westaway D, Stubblebine WH, Prusiner SB, Dearmond SJ. PMID: 3755672.
View in:
PubMed Mentions:
75 Fields:
Translation:
HumansAnimalsCells
-
Molecular characteristics of prion rods purified from scrapie-infected hamster brains. J Infect Dis. 1986 Jul; 154(1):110-20.
McKinley MP, Braunfeld MB, Bellinger CG, Prusiner SB. PMID: 2872252.
View in:
PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
Scrapie and cellular prion proteins share polypeptide epitopes. J Infect Dis. 1986 May; 153(5):848-54.
Barry RA, Kent SB, McKinley MP, Meyer RK, DeArmond SJ, Hood LE, Prusiner SB. PMID: 2422294.
View in:
PubMed Mentions:
8 Fields:
Translation:
Animals
-
Separation and properties of cellular and scrapie prion proteins. Proc Natl Acad Sci U S A. 1986 Apr; 83(8):2310-4.
Meyer RK, McKinley MP, Bowman KA, Braunfeld MB, Barry RA, Prusiner SB. PMID: 3085093; PMCID: PMC323286.
View in:
PubMed Mentions:
164 Fields:
Translation:
AnimalsCells
-
Conservation of the cellular gene encoding the scrapie prion protein. Nucleic Acids Res. 1986 Mar 11; 14(5):2035-44.
Westaway D, Prusiner SB. PMID: 2870469; PMCID: PMC339641.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
-
H2 histamine receptors on the epithelial cells of choroid plexus. J Neurochem. 1986 Feb; 46(2):489-93.
Crook RB, Farber MB, Prusiner SB. PMID: 3001227.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
-
Scrapie prion proteins are synthesized in neurons. Am J Pathol. 1986 Jan; 122(1):1-5.
Kretzschmar HA, Prusiner SB, Stowring LE, DeArmond SJ. PMID: 3079955; PMCID: PMC1888142.
View in:
PubMed Mentions:
113 Fields:
Translation:
AnimalsCells
-
Biology and structure of scrapie prions. Int Rev Neurobiol. 1986; 28:1-57.
McKinley MP, Prusiner SB. PMID: 3100471.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Replication of scrapie prions in hamster eyes precedes retinal degeneration. Ophthalmic Res. 1986; 18(4):230-5.
Hogan RN, Bowman KA, Baringer JR, Prusiner SB. PMID: 3095759.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals
-
Transmission of scrapie in hamsters. J Infect Dis. 1985 Nov; 152(5):971-8.
Prusiner SB, Cochran SP, Alpers MP. PMID: 3930630.
View in:
PubMed Mentions:
22 Fields:
Translation:
Animals
-
Cloning and characterization of the myelin basic protein gene from mouse: one gene can encode both 14 kd and 18.5 kd MBPs by alternate use of exons. Cell. 1985 Aug; 42(1):139-48.
Takahashi N, Roach A, Teplow DB, Prusiner SB, Hood L. PMID: 2410136.
View in:
PubMed Mentions:
62 Fields:
Translation:
AnimalsCells
-
A microangiopathic syndrome of encephalopathy, hearing loss, and retinal arteriolar occlusions. Neurology. 1985 Aug; 35(8):1113-21.
Monteiro ML, Swanson RA, Coppeto JR, Cuneo RA, DeArmond SJ, Prusiner SB. PMID: 4022345.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
Antibodies to the scrapie protein decorate prion rods. J Immunol. 1985 Jul; 135(1):603-13.
Barry RA, McKinley MP, Bendheim PE, Lewis GK, DeArmond SJ, Prusiner SB. PMID: 3923112.
View in:
PubMed Mentions:
19 Fields:
Translation:
Animals
-
Identification of prion amyloid filaments in scrapie-infected brain. Cell. 1985 May; 41(1):221-35.
DeArmond SJ, McKinley MP, Barry RA, Braunfeld MB, McColloch JR, Prusiner SB. PMID: 3922627.
View in:
PubMed Mentions:
85 Fields:
Translation:
Animals
-
Scrapie and Creutzfeldt-Jakob disease prion proteins share physical properties and antigenic determinants. Proc Natl Acad Sci U S A. 1985 Feb; 82(4):997-1001.
Bendheim PE, Bockman JM, McKinley MP, Kingsbury DT, Prusiner SB. PMID: 2579394; PMCID: PMC397180.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansAnimals
-
Scrapie PrP 27-30 is a sialoglycoprotein. J Virol. 1985 Feb; 53(2):596-606.
Bolton DC, Meyer RK, Prusiner SB. PMID: 3918176; PMCID: PMC254675.
View in:
PubMed Mentions:
73 Fields:
-
Creutzfeldt-Jakob disease prion proteins in human brains. N Engl J Med. 1985 Jan 10; 312(2):73-8.
Bockman JM, Kingsbury DT, McKinley MP, Bendheim PE, Prusiner SB. PMID: 3917302.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansAnimals
-
Prions--infectious pathogens causing the spongiform encephalopathies. CRC Crit Rev Clin Neurobiol. 1985; 1(3):181-200.
Prusiner SB, Kingsbury DT. PMID: 3915974.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
-
Scrapie and Creutzfeldt-Jakob disease prions. Microbiol Sci. 1985; 2(2):33-9.
Prusiner SB, Barry RA, McKinley MP, Bellinger CG, Meyer RK, DeArmond SJ, Kingsbury DT. PMID: 3940147.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
-
Scrapie prions, brain amyloid, and senile dementia. Curr Top Cell Regul. 1985; 26:79-95.
Prusiner SB. PMID: 2934227.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
-
Molecular characteristics of the major scrapie prion protein. Biochemistry. 1984 Dec 04; 23(25):5898-906.
Bolton DC, McKinley MP, Prusiner SB. PMID: 6395885.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
-
Prions. Sci Am. 1984 Oct; 251(4):50-9.
Prusiner SB. PMID: 6385236.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimals
-
Bitemporal hypometabolism in Creutzfeldt-Jakob disease measured by positron emission tomography with [18F]-2-fluorodeoxyglucose. J Comput Assist Tomogr. 1984 Oct; 8(5):978-81.
Friedland RP, Prusiner SB, Jagust WJ, Budinger TF, Davis RL. PMID: 6381559.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Antibodies to a scrapie prion protein. Nature. 1984 Aug 2-8; 310(5976):418-21.
Bendheim PE, Barry RA, DeArmond SJ, Stites DP, Prusiner SB. PMID: 6431296.
View in:
PubMed Mentions:
68 Fields:
Translation:
Animals
-
Purification and structural studies of a major scrapie prion protein. Cell. 1984 Aug; 38(1):127-34.
Prusiner SB, Groth DF, Bolton DC, Kent SB, Hood LE. PMID: 6432339.
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PubMed Mentions:
157 Fields:
Translation:
AnimalsCells
-
Some speculations about prions, amyloid, and Alzheimer's disease. N Engl J Med. 1984 Mar 08; 310(10):661-3.
Prusiner SB. PMID: 6363926.
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PubMed Mentions:
62 Fields:
Translation:
HumansAnimals
-
Hormones and neurotransmitters control cyclic AMP metabolism in choroid plexus epithelial cells. J Neurochem. 1984 Feb; 42(2):340-50.
Crook RB, Farber MB, Prusiner SB. PMID: 6198461.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Prions: novel infectious pathogens. Adv Virus Res. 1984; 29:1-56.
Prusiner SB. PMID: 6241423.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimals
-
Retinal degeneration in experimental Creutzfeldt-Jakob disease. Lab Invest. 1983 Dec; 49(6):708-15.
Hogan RN, Kingsbury DT, Baringer JR, Prusiner SB. PMID: 6361375.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
-
Scrapie prions aggregate to form amyloid-like birefringent rods. Cell. 1983 Dec; 35(2 Pt 1):349-58.
Prusiner SB, McKinley MP, Bowman KA, Bolton DC, Bendheim PE, Groth DF, Glenner GG. PMID: 6418385.
View in:
PubMed Mentions:
304 Fields:
Translation:
Animals
-
A protease-resistant protein is a structural component of the scrapie prion. Cell. 1983 Nov; 35(1):57-62.
McKinley MP, Bolton DC, Prusiner SB. PMID: 6414721.
View in:
PubMed Mentions:
269 Fields:
-
Characterization of cloned cDNA representing rat myelin basic protein: absence of expression in brain of shiverer mutant mice. Cell. 1983 Oct; 34(3):799-806.
Roach A, Boylan K, Horvath S, Prusiner SB, Hood LE. PMID: 6194889.
View in:
PubMed Mentions:
77 Fields:
Translation:
AnimalsCells
-
Replication of the scrapie agent in hamster brain precedes neuronal vacuolation. J Neuropathol Exp Neurol. 1983 Sep; 42(5):539-47.
Baringer JR, Bowman KA, Prusiner SB. PMID: 6411868.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Genetic control of scrapie and Creutzfeldt-Jakob disease in mice. J Immunol. 1983 Jul; 131(1):491-6.
Kingsbury DT, Kasper KC, Stites DP, Watson JD, Hogan RN, Prusiner SB. PMID: 6408182.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansAnimals
-
Resistance of the scrapie agent to inactivation by psoralens. Photochem Photobiol. 1983 May; 37(5):539-45.
McKinley MP, Masiarz FR, Isaacs ST, Hearst JE, Prusiner SB. PMID: 6410423.
View in:
PubMed Mentions:
8 Fields:
Translation:
Animals
-
Identification of a protein that purifies with the scrapie prion. Science. 1982 Dec 24; 218(4579):1309-11.
Bolton DC, McKinley MP, Prusiner SB. PMID: 6815801.
View in:
PubMed Mentions:
365 Fields:
Translation:
Animals
-
Further purification and characterization of scrapie prions. Biochemistry. 1982 Dec 21; 21(26):6942-50.
Prusiner SB, Bolton DC, Groth DF, Bowman KA, Cochran SP, McKinley MP. PMID: 6818988.
View in:
PubMed Mentions:
125 Fields:
Translation:
Animals
-
Immunological studies of scrapie infection. J Neuroimmunol. 1982 Nov; 3(3):187-201.
Kasper KC, Stites DP, Bowman KA, Panitch H, Prusiner SB. PMID: 6183292.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Viroids and prions. Proc Natl Acad Sci U S A. 1982 Sep; 79(17):5220-4.
Diener TO, McKinley MP, Prusiner SB. PMID: 6813855; PMCID: PMC346867.
View in:
PubMed Mentions:
26 Fields:
Translation:
Cells
-
Research on scrapie. Lancet. 1982 Aug 28; 2(8296):494-5.
Prusiner SB. PMID: 6125659.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
-
Kuru with incubation periods exceeding two decades. Ann Neurol. 1982 Jul; 12(1):1-9.
Prusiner SB, Gajdusek C, Alpers MP. PMID: 7114816.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
Novel proteinaceous infectious particles cause scrapie. Science. 1982 Apr 09; 216(4542):136-44.
Prusiner SB. PMID: 6801762.
View in:
PubMed Mentions:
1643 Fields:
Translation:
Animals
-
Measurement of the scrapie agent using an incubation time interval assay. Ann Neurol. 1982 Apr; 11(4):353-8.
Prusiner SB, Cochran SP, Groth DF, Downey DE, Bowman KA, Martinez HM. PMID: 6808890.
View in:
PubMed Mentions:
116 Fields:
Translation:
Animals
-
Reversible chemical modification of the scrapie agent. Science. 1981 Dec 11; 214(4526):1259-61.
McKinley MP, Masiarz FR, Prusiner SB. PMID: 6795721.
View in:
PubMed Mentions:
11 Fields:
Translation:
Animals
-
Scrapie agent contains a hydrophobic protein. Proc Natl Acad Sci U S A. 1981 Nov; 78(11):6675-9.
Prusiner SB, McKinley MP, Groth DF, Bowman KA, Mock NI, Cochran SP, Masiarz FR. PMID: 6273882; PMCID: PMC349112.
View in:
PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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Culture and characterization of epithelial cells from bovine choroid plexus. J Neurochem. 1981 Oct; 37(4):845-54.
Crook RB, Kasagami H, Prusiner SB. PMID: 6119356.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Membrane populations of bovine choroid plexus: separation by density gradient centrifugation in modified colloidal silica. J Neurochem. 1981 Sep; 37(3):768-74.
Mamelok RD, Macrae DR, Benet LZ, Prusiner SB. PMID: 6115891.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Thiocyanate and hydroxyl ions inactivate the scrapie agent. Proc Natl Acad Sci U S A. 1981 Jul; 78(7):4606-10.
Prusiner SB, Groth DF, McKinley MP, Cochran SP, Bowman KA, Kasper KC. PMID: 6794034; PMCID: PMC319842.
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PubMed Mentions:
23 Fields:
Translation:
Animals
-
Scrapie-associated particles in postsynaptic processes. Further ultrastructural studies. J Neuropathol Exp Neurol. 1981 May; 40(3):281-8.
Baringer JR, Prusiner SB, Wong JS. PMID: 7194369.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Kinetics of D-glucose transport into renal membrane vesicles: measurements using a vacuum manifold apparatus. J Biochem Biophys Methods. 1981 Mar; 4(3-4):147-53.
Mamelok RD, Macrae DR, Hittelman K, Hoefer JP, Prusiner SB. PMID: 7240643.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Determination of scrapie agent titer from incubation period measurements in hamsters. Adv Exp Med Biol. 1981; 134:385-99.
Prusiner SB, Cochran SP, Downey DE, Groth DF. PMID: 7194570.
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PubMed Mentions:
9 Fields:
Translation:
Animals
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Progressive retinal degeneration in scrapie-infected hamsters: a light and electron microscopic analysis. Lab Invest. 1981 Jan; 44(1):34-42.
Hogan RN, Baringer JR, Prusiner SB. PMID: 6779055.
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PubMed Mentions:
9 Fields:
Translation:
Animals
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Toward development of assays for scrapie-specific antibodies. Adv Exp Med Biol. 1981; 134:401-13.
Kasper KC, Bowman K, Stites DP, Prusiner SB. PMID: 6261543.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Disorders of glutamate metabolism and neurological dysfunction. Annu Rev Med. 1981; 32:521-42.
Prusiner SB. PMID: 7013687.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
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Brain tissue from persons dying of Creutzfeldt-Jakob disease causes scrapie-like encephalopathy in goats. Ann Neurol. 1980 Dec; 8(6):628-32.
Hadlow WJ, Prusiner SB, Kennedy RC, Race RE. PMID: 7011169.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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Gel electrophoresis and glass permeation chromatography of the hamster scrapie agent after enzymatic digestion and detergent extraction. Biochemistry. 1980 Oct 14; 19(21):4892-8.
Prusiner SB, Groth DF, Cochran SP, McKinley MP, Masiarz FR. PMID: 6775698.
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PubMed Mentions:
10 Fields:
Translation:
Animals
-
Molecular properties, partial purification, and assay by incubation period measurements of the hamster scrapie agent. Biochemistry. 1980 Oct 14; 19(21):4883-91.
Prusiner SB, Groth DF, Cochran SP, Masiarz FR, McKinley MP, Martinez HM. PMID: 6775697.
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PubMed Mentions:
48 Fields:
Translation:
Animals
-
Biohazards of investigations on the transmissible spongiform encephalopathies. Rev Infect Dis. 1980 Sep-Oct; 2(5):713-24.
Chatigny MA, Prusiner SB. PMID: 6302811.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsPHPublic Health
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Experimental scrapie in the mouse: electrophoretic and sedimentation properties of the partially purified agent. J Neurochem. 1980 Sep; 35(3):574-82.
Prusiner SB, Garfin DE, Cochran SP, McKinley MP, Groth DF, Hadlow WJ, Race RE, Eklund CM. PMID: 6778963.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Separation of membrane-bound gamma-glutamyl transpeptidase from brush border transport and enzyme activities. Biochemistry. 1980 May 27; 19(11):2367-73.
Mamelok RD, Groth DF, Prusiner SB. PMID: 6104508.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Electrophoretic properties of the scrapie agent in agarose gels. Proc Natl Acad Sci U S A. 1980 May; 77(5):2984-8.
Prusiner SB, Groth DF, Bildstein C, Masiarz FR, McKinley MP, Cochran SP. PMID: 6771764; PMCID: PMC349531.
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PubMed Mentions:
12 Fields:
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Slow viruses: molecular properties of the agents causing scrapie in mice and hamsters. Prog Clin Biol Res. 1980; 39:73-89.
Prusiner SB, Cochran SP, Baringer JR, Groth D, Masiarz F, McKinley M, Bildstein C, Garfin D, Hadlow WJ, Race RE, Eklund CM. PMID: 6773068.
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PubMed Mentions: Fields:
Translation:
Animals
-
Evaluation of a class III biological safety cabinet for enclosure of an ultracentrifuge. Appl Environ Microbiol. 1979 Nov; 38(5):934-9.
Chatigny MA, Dunn S, Ishimaru K, Eagleson JA, Prusiner SB. PMID: 543704; PMCID: PMC243612.
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PubMed Mentions:
2 Fields:
Translation:
CellsPHPublic Health
-
Partial purification and evidence for multiple molecular forms of the scrapie agent. Biochemistry. 1978 Nov 14; 17(23):4993-9.
Prusiner SB, Hadlow WJ, Garfin DE, Cochran SP, Baringer JR, Race RE, Eklund CM. PMID: 102338.
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PubMed Mentions:
22 Fields:
Translation:
Animals
-
Sedimentation characteristics of the scrapie agent from murine spleen and brain. Biochemistry. 1978 Nov 14; 17(23):4987-92.
Prusiner SB, Hadlow WJ, Eklund CM, Race RE, Cochran SP. PMID: 214106.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Mitogen stimulation of splenocytes from mice infected with scrapie agent. J Infect Dis. 1978 Sep; 138(3):396-400.
Garfin DE, Stites DP, Perlman JD, Cochran SP, Prusiner SB. PMID: 568156.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Preservation by freezing of glucose and alanine transport into kidney membrane vesicles. Anal Biochem. 1978 Sep; 89(2):324-31.
Hittelman K, Mamelok RD, Prusiner SB. PMID: 727434.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Experimental scrapie in mice: ultrastructural observations. Ann Neurol. 1978 Sep; 4(3):205-11.
Baringer JR, Prusiner SB. PMID: 568909.
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PubMed Mentions:
11 Fields:
Translation:
Animals
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Suppression of polyclonal B cell activation in scrapie-infected C3H/HeJ mice. J Immunol. 1978 Jun; 120(6):1986-90.
Garfin DE, Stites DP, Zitnik LA, Prusiner SB. PMID: 307027.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Partial purification and kinetics of gamma-glutamyl transpeptidase from bovine choroid plexus. J Neurochem. 1978 Jun; 30(6):1253-9.
Prusiner PE, Prusiner SB. PMID: 27580.
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PubMed Mentions:
6 Fields:
Translation:
Animals
-
Modulation of gamma-glutamyl transpeptidase activity from bovine choroid plexus. J Neurochem. 1978 Jun; 30(6):1261-7.
Prusiner PE, Prusiner SB. PMID: 27581.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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An approach to the isolation of biological particles using sedimentation analysis. J Biol Chem. 1978 Feb 10; 253(3):916-21.
Prusiner SB. PMID: 621210.
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PubMed Mentions:
2 Fields:
Translation:
Animals
-
Evidence for hydrophobic domains on the surface of the scrapie agent. Trans Am Neurol Assoc. 1978; 103:62-4.
Prusiner SB, Garfin DE, Cochran SP, Baringer JR, Hadlow WJ, Eklund CM, Race RE. PMID: 117582.
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PubMed Mentions:
2 Fields:
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Sedimentation properties of the scrapie agent. Proc Natl Acad Sci U S A. 1977 Oct; 74(10):4656-60.
Prusiner SB, Hadlow WJ, Eklund CM, Race RE. PMID: 412193; PMCID: PMC432006.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Comparative studies on membranes from bovine choroid plexus and rat kidney cortex. Life Sci. 1977 Sep 15; 21(6):833-40.
Kirk G, Prusiner SB. PMID: 21337.
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Translation:
AnimalsCells
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Carotidynia. Neurology. 1977 Jan; 27(1):43-6.
Raskin NH, Prusiner S. PMID: 556819.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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A novel mechanism for group translocation: substrate-product reutilization by gamma-glutamyl transpeptidase in peptide and amino acid transport. J Cell Physiol. 1976 Dec; 89(4):853-63.
Prusiner S, Doak CW, Kirk G. PMID: 13082.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Regulation of glutaminase B in Escherichia coli. I. Purification, properties, and cold lability. J Biol Chem. 1976 Jun 10; 251(11):3447-56.
Prusiner S, Davis JN, Stadtman ER. PMID: 6454.
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PubMed Mentions:
6 Fields:
Translation:
Cells
-
Regulation of glutaminase B in Escherichia coli. II. Modulaltion of activity by carbosylate and borate ions. J Biol Chem. 1976 Jun 10; 251(11):3457-62.
Prusiner S, Stadtman ER. PMID: 776969.
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PubMed Mentions:
2 Fields:
Translation:
Cells
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Regulation of glutaminase B in Escherichia coli. III. Control by nucleotides and divalent cations. J Biol Chem. 1976 Jun 10; 251(11):3463-9.
Prusiner S, Stadtman ER. PMID: 776970.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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Regulation of glutaminase levels in Escherichia coli. J Bacteriol. 1975 Sep; 123(3):992-9.
Prusiner S. PMID: 239927; PMCID: PMC235824.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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Regulation of glutamine synthetase from Bacillus subtilis by divalent cations, feedback inhibitors, and L-glutamine. J Biol Chem. 1974 Jan 10; 249(1):257-64.
Deuel TF, Prusiner S. PMID: 4149044.
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PubMed Mentions:
31 Fields:
Translation:
Cells
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Stain for glutaminase activity. Anal Biochem. 1973 Jul; 54(1):272-5.
Davis JN, Prusiner S. PMID: 4125255.
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PubMed Mentions:
1 Fields:
Translation:
Cells
-
Adenosine 3':5'-cyclic monophosphate control of the enzymes of glutamine metabolism in Escherichia coli. Proc Natl Acad Sci U S A. 1972 Oct; 69(10):2922-6.
Prusiner S, Miller RE, Valentine RC. PMID: 4404145; PMCID: PMC389675.
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PubMed Mentions:
45 Fields:
Translation:
Cells
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On the regulation of glutaminase in E. coli: metabolite control. Biochem Biophys Res Commun. 1971 Dec 17; 45(6):1474-81.
Prusiner S, Stadtman ER. PMID: 4399639.
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PubMed Mentions:
7 Fields:
Translation:
Cells
-
Vacuum manifold for rapid assay of enzymes using radioactive tracers and ion exchange chromatography. Rev Sci Instrum. 1971 Apr; 42(4):493-4.
Prusiner SB, Milner LS, Long CW, Myers ML. PMID: 5546271.
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PubMed Mentions: Fields:
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A rapid radioactive assay for glutamine synthetase, glutaminase, asparagine synthetase, and asparaginase. Anal Biochem. 1970 Oct; 37(2):429-38.
Prusiner S, Milner L. PMID: 4920285.
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PubMed Mentions:
38 Fields:
Translation:
Cells
-
Metabolic control in isolated brown fat cells. Lipids. 1970 Feb; 5(2):204-9.
Lindberg O, Prusiner SB, Cannon B, Ching TM, Eisenhardt RH. PMID: 4314248.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Spectroscopic evidence for the control of respiration prior to phosphorylation in hamster brown fat cells. J Biol Chem. 1970 Jan 25; 245(2):382-9.
Prusiner S. PMID: 5412065.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Control of metabolism in brown adipose tissue. Lipids. 1970 Jan; 5(1):1-14.
Williamson JR, Prusiner S, Olson MS, Fukami M. PMID: 5418206.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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[Energetic disturbance of cation transport as a cause of intracellular brain edema]. Acta Neurochir (Wien). 1970; 22(2):129-66.
Reulen HJ, Steude U, Brendel W, Hilber C, Prusiner S. PMID: 5521226.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Hypothermic protection against cerebral edema of ischemia. Arch Neurol. 1968 Dec; 19(6):623-7.
Prusiner S, Wolfson SK. PMID: 5726773.
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PubMed Mentions:
1 Fields:
Translation:
Animals
-
Oxidative metabolism in cells isolated from brown adipose tissue. 2. Catecholamine regulated respiratory control. Eur J Biochem. 1968 Dec; 7(1):51-7.
Prusiner SB, Cannon B, Ching TM, Lindberg O. PMID: 5707712.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Thermodynamic cosiderations of mammalian thermogenesis. Nature. 1968 Oct 19; 220(5164):235-7.
Prusiner S, Poe M. PMID: 5684848.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Oxidative metabolism in cells isolated from brown adipose tissue. 1. Catecholamine and fatty acid stimulation of respiration. Eur J Biochem. 1968 Oct 17; 6(1):15-22.
Prusiner SB, Cannon B, Lindberg O. PMID: 5725810.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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The regulation of oxidative metabolism of isolated brown fat cells. Biochem Biophys Res Commun. 1968 Mar 12; 30(5):508-15.
Prusiner SB, Eisenhardt RH, Rylander E, Lindberg O. PMID: 5645437.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Pyridine nucleotide changes during thermogenesis in brown fat tissue in vivo. Arch Biochem Biophys. 1968 Feb; 123(2):368-77.
Prusiner S, Williamson JR, Chance B, Paddle BM. PMID: 4296052.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Relationship of acidemia to cerebral edema. Arch Surg. 1965 Dec; 91(6):902-5.
Prusiner SB, Moskovitz PA, Wolfson SK. PMID: 5842950.
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PubMed Mentions: Fields:
Translation:
Animals