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Michael Geschwind, MD, PhD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentNeurology
Address675 Nelson Rising Lane
San Francisco CA 94158
Phone415-476-2900
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPostdoctoral Studies 2000Graduate Division/Neurology

    Collapse Overview 
    Collapse Overview
    Dr. Geschwind received his M.D.and Ph.D. in neuroscience through the National Institutes of Health (NIH)-sponsored Medical Scientist Training Program (MSTP) at the Albert Einstein College of Medicine in New York. He completed his internship in internal medicine at the University of California, Los Angeles (UCLA) Medical Center, his neurology residency at the Johns Hopkins University School of Medicine in Baltimore and his fellowship in behavioral neurology at the UCSF Memory and Aging Center (MAC). He is now on faculty in the UCSF Department of Neurology where he is Professor of Neurology at the Memory and Aging Center (MAC).

    Dr. Geschwind evaluates new patients in the MAC clinic and participates in the continued management and care for these patients in the continuity clinic. He is active in the training of medical students, residents and neurobehavior fellows at UCSF. Dr. Geschwind teaches national courses, and lectures both nationally and internationally, on dementia including rapidly progressive dementias, such as prion diseases and antibody-mediated dementias. He has been a guest editor for the American Academy of Neurology (AAN) Continuum Dementia edition, and has contributed to editions on Dementia and Infectious Disease. He also served on the AAN’s committee for dementia criteria.

    Dr. Geschwind’s primary research interest is the assessment, management and treatment of rapidly progressive dementias, including prion diseases such as Jakob-Creutzfeldt disease (CJD). Dr. Geschwind helped establish an inpatient hospital program for the assessment of rapidly progressive dementias at UCSF, the first of its kind in the country. He helped to run the first U.S. treatment study for CJD. He also has an active research interest in cognitive dysfunction in movement disorders, such as Huntington’s Disease, ataxia, Corticobasal Degeneration (CBD), Progressive Supranuclear Palsy (PSP), other parkinsonian dementias, and neurogenetic disorders.

    Dr. Geschwind also directs the UCSF Memory and Aging Center (UCSF MAC) Huntington's Disease (HD) center, which has been designated an Huntington's Disease Society of America Center of Excellence. He has been an active investigator for several HD observational and interventional studies. He also was the site investigator for a treatment trial for patients with Cerebral Autosomal Dominant Arteriopathy Subcortical Infarcts and Leukoencephalopathy (CADASIL). He co-directs the UCSF MAC autoimmune clinic in which patients with suspected or known antibody mediated encephalopathies are evaluated and managed.


    Collapse Research 
    Collapse Research Activities and Funding
    Predicting progression of human prion disease
    NIH/NIA R01AG031189Dec 1, 2007 - Jun 30, 2018
    Role: Principal Investigator
    New Clinical Approaches to Creutzfeldt-Jakob Disease
    NIH/NIA K23AG021989Sep 15, 2003 - Aug 31, 2008
    Role: Principal Investigator

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    Collapse Global Health
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Shanbhag NM, Geschwind M, DiGiovanna JJ, Groden C, Godfrey R, Yousefzadeh MJ, Wade EA, Niedernhofer LJ, Malicdan MCV, Kraemer KH, Gahl WA, Toro C. Neurodegeneration as the presenting symptom in 2 adults with xeroderma pigmentosum complementation group F. Neurol Genet. 2018 Jun; 4(3):e240. PMID: 29892709.
      View in: PubMed
    2. Binks S, Varley J, Lee W, Makuch M, Elliott K, Gelfand JM, Jacob S, Leite MI, Maddison P, Chen M, Geschwind M, Grant E, Sen A, Waters P, McCormack M, Cavalleri GL, Barnardo M, Knight JC, Irani SR. Distinct HLA associations of LGI1 and CASPR2-antibody diseases. Brain. 2018 May 18. PMID: 29788256.
      View in: PubMed
    3. Kim MO, Takada LT, Wong K, Forner SA, Geschwind M. Genetic PrP Prion Diseases. Cold Spring Harb Perspect Biol. 2018 May 01; 10(5). PMID: 28778873.
      View in: PubMed
    4. Ngo K, Aker M, Petty LE, Chen J, Cavalcanti F, Nelson AB, Hassin-Baer S, Geschwind M, Perlman S, Italiano D, Laganà A, Cavallaro S, Coppola G, Below JE, Fogel BL. Expanding the global prevalence of spinocerebellar ataxia type 42. Neurol Genet. 2018 Jun; 4(3):e232. PMID: 29629410.
      View in: PubMed
    5. Erkkinen MG, Kim MO, Geschwind M. Clinical Neurology and Epidemiology of the Major Neurodegenerative Diseases. Cold Spring Harb Perspect Biol. 2018 Apr 02; 10(4). PMID: 28716886.
      View in: PubMed
    6. Thompson J, Bi M, Murchison AG, Makuch M, Bien CG, Chu K, Farooque P, Gelfand JM, Geschwind M, Hirsch LJ, Somerville E, Lang B, Vincent A, Leite MI, Waters P, Irani SR. The importance of early immunotherapy in patients with faciobrachial dystonic seizures. Brain. 2018 Feb 01; 141(2):348-356. PMID: 29272336.
      View in: PubMed
    7. Geschwind M, Murray K. Differential diagnosis with other rapid progressive dementias in human prion diseases. Handb Clin Neurol. 2018; 153:371-397. PMID: 29887146.
      View in: PubMed
    8. Takada LT, Kim MO, Metcalf S, Gala II, Geschwind M. Prion disease. Handb Clin Neurol. 2018; 148:441-464. PMID: 29478593.
      View in: PubMed
    9. Staffaroni AM, Elahi FM, McDermott D, Marton K, Karageorgiou E, Sacco S, Paoletti M, Caverzasi E, Hess CP, Rosen HJ, Geschwind M. Neuroimaging in Dementia. Semin Neurol. 2017 Oct; 37(5):510-537. PMID: 29207412.
      View in: PubMed
    10. Figueroa KP, Gan SR, Perlman S, Wilmot G, Gomez CM, Schmahmann J, Paulson H, Shakkottai VG, Ying SH, Zesiewicz T, Bushara K, Geschwind M, Xia G, Subramony SH, Ashizawa T, Pulst SM, Kuo SH. C9orf72 repeat expansions as genetic modifiers for depression in spinocerebellar ataxias. Mov Disord. 2018 Mar; 33(3):497-498. PMID: 29193335.
      View in: PubMed
    11. Kuo PH, Gan SR, Wang J, Lo RY, Figueroa KP, Tomishon D, Pulst SM, Perlman S, Wilmot G, Gomez CM, Schmahmann JD, Paulson H, Shakkottai VG, Ying SH, Zesiewicz T, Bushara K, Geschwind M, Xia G, Subramony SH, Ashizawa T, Kuo SH. Dystonia and ataxia progression in spinocerebellar ataxias. Parkinsonism Relat Disord. 2017 Dec; 45:75-80. PMID: 29089256.
      View in: PubMed
    12. Gan SR, Wang J, Figueroa KP, Pulst SM, Tomishon D, Lee D, Perlman S, Wilmot G, Gomez CM, Schmahmann J, Paulson H, Shakkottai VG, Ying SH, Zesiewicz T, Bushara K, Geschwind M, Xia G, Subramony SH, Ashizawa T, Kuo SH. Postural Tremor and Ataxia Progression in Spinocerebellar Ataxias. Tremor Other Hyperkinet Mov (N Y). 2017; 7:492. PMID: 29057148.
      View in: PubMed
    13. Kim H, Kim JH, Possin KL, Winer J, Geschwind M, Xu D, Hess CP. Surface-based morphometry reveals caudate subnuclear structural damage in patients with premotor Huntington disease. Brain Imaging Behav. 2017 Oct; 11(5):1365-1372. PMID: 27730480.
      View in: PubMed
    14. Abad CL, Dhaliwal G, Geschwind M, Saint S, Safdar N. Mass Confusion. J Hosp Med. 2017 09; 12(9):750-754. PMID: 28914282.
      View in: PubMed
    15. Luo L, Wang J, Lo RY, Figueroa KP, Pulst SM, Kuo PH, Perlman S, Wilmot G, Gomez CM, Schmahmann J, Paulson H, Shakkottai VG, Ying SH, Zesiewicz T, Bushara K, Geschwind M, Xia G, Subramony SH, Ashizawa T, Kuo SH. The Initial Symptom and Motor Progression in Spinocerebellar Ataxias. Cerebellum. 2017 Jun; 16(3):615-622. PMID: 27848087.
      View in: PubMed
    16. Fernández-Fournier M, Perry DC, Tartaglia MC, de May M, Boxer A, Coppola G, Christine CW, Huang EJ, Seeley WW, Miller BL, DeArmond SJ, Grinberg LT, Geschwind M. Precipitous Deterioration of Motor Function, Cognition, and Behavior. JAMA Neurol. 2017 May 01; 74(5):591-596. PMID: 28264087.
      View in: PubMed
    17. Possin KL, Kim H, Geschwind M, Moskowitz T, Johnson ET, Sha SJ, Apple A, Xu D, Miller BL, Finkbeiner S, Hess CP, Kramer JH. Egocentric and allocentric visuospatial working memory in premotor Huntington's disease: A double dissociation with caudate and hippocampal volumes. Neuropsychologia. 2017 Jul 01; 101:57-64. PMID: 28427989.
      View in: PubMed
    18. Fong JC, Rojas JC, Bang J, Legati A, Rankin KP, Forner S, Miller ZA, Karydas AM, Coppola G, Grouse CK, Ralph J, Miller BL, Geschwind M. Genetic Prion Disease Caused by PRNP Q160X Mutation Presenting with an Orbitofrontal Syndrome, Cyclic Diarrhea, and Peripheral Neuropathy. J Alzheimers Dis. 2017; 55(1):249-258. PMID: 27716661.
      View in: PubMed
    19. Takada LT, Kim MO, Cleveland RW, Wong K, Forner SA, Gala II, Fong JC, Geschwind M. Genetic prion disease: Experience of a rapidly progressive dementia center in the United States and a review of the literature. Am J Med Genet B Neuropsychiatr Genet. 2017 Jan; 174(1):36-69. PMID: 27943639.
      View in: PubMed
    20. Coulthart MB, Geschwind M, Qureshi S, Phielipp N, Demarsh A, Abrams JY, Belay E, Gambetti P, Jansen GH, Lang AE, Schonberger LB. A case cluster of variant Creutzfeldt-Jakob disease linked to the Kingdom of Saudi Arabia. Brain. 2016 10; 139(Pt 10):2609-2616. PMID: 27671029.
      View in: PubMed
    21. Ljubenkov PA, Geschwind M. Dementia. Semin Neurol. 2016 Aug; 36(4):397-404. PMID: 27643909.
      View in: PubMed
    22. Biswas MHU, Almeida S, Lopez-Gonzalez R, Mao W, Zhang Z, Karydas A, Geschwind M, Biernat J, Mandelkow EM, Futai K, Miller BL, Gao FB. MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations. Stem Cell Reports. 2016 09 13; 7(3):316-324. PMID: 27594586.
      View in: PubMed
    23. Geschwind M, Paras N. Deutetrabenazine for Treatment of Chorea in Huntington Disease. JAMA. 2016 Jul 05; 316(1):33-5. PMID: 27380339.
      View in: PubMed
    24. Geschwind M. Rapidly Progressive Dementia. Continuum (Minneap Minn). 2016 Apr; 22(2 Dementia):510-37. PMID: 27042906; PMCID: PMC4879977.
    25. Graus F, Titulaer MJ, Balu R, Benseler S, Bien CG, Cellucci T, Cortese I, Dale RC, Gelfand JM, Geschwind M, Glaser CA, Honnorat J, Höftberger R, Iizuka T, Irani SR, Lancaster E, Leypoldt F, Prüss H, Rae-Grant A, Reindl M, Rosenfeld MR, Rostásy K, Saiz A, Venkatesan A, Vincent A, Wandinger KP, Waters P, Dalmau J. A clinical approach to diagnosis of autoimmune encephalitis. Lancet Neurol. 2016 Apr; 15(4):391-404. PMID: 26906964.
      View in: PubMed
    26. Savard M, Irani SR, Guillemette A, Gosselin-Lefebvre S, Geschwind M, Jansen GH, Gould PV, Laforce R. Creutzfeldt-Jakob Disease-Like Periodic Sharp Wave Complexes in Voltage-Gated Potassium Channel-Complex Antibodies Encephalitis: A Case Report. J Clin Neurophysiol. 2016 Feb; 33(1):e1-4. PMID: 26375660; PMCID: PMC4740210 [Available on 02/01/17].
    27. Geschwind M. Prion Diseases. Continuum (Minneap Minn). 2015 Dec; 21(6 Neuroinfectious Disease):1612-38. PMID: 26633779; PMCID: PMC4879966.
    28. Lo RY, Figueroa KP, Pulst SM, Perlman S, Wilmot G, Gomez C, Schmahmann J, Paulson H, Shakkottai VG, Ying S, Zesiewicz T, Bushara K, Geschwind M, Xia G, Yu JT, Lee LE, Ashizawa T, Subramony SH, Kuo SH. Depression and clinical progression in spinocerebellar ataxias. Parkinsonism Relat Disord. 2016 Jan; 22:87-92. PMID: 26644294; PMCID: PMC4695274 [Available on 01/01/17].
    29. Tousseyn T, Bajsarowicz K, Sánchez H, Gheyara A, Oehler A, Geschwind M, DeArmond B, DeArmond SJ. Prion Disease Induces Alzheimer Disease-Like Neuropathologic Changes. J Neuropathol Exp Neurol. 2015 Sep; 74(9):873-88. PMID: 26226132.
      View in: PubMed
    30. Watts JC, Giles K, Serban A, Patel S, Oehler A, Bhardwaj S, Guan S, Greicius MD, Miller BL, DeArmond SJ, Geschwind M, Prusiner SB. Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation. Ann Neurol. 2015 Oct; 78(4):540-53. PMID: 26094969; PMCID: PMC4711268 [Available on 10/01/16].
    31. Ng AS, Kramer J, Centurion A, Dalmau J, Huang E, Cotter JA, Geschwind M. Clinico-pathological correlation in adenylate kinase 5 autoimmune limbic encephalitis. J Neuroimmunol. 2015 Oct 15; 287:31-5. PMID: 26439959; PMCID: PMC4879958 [Available on 10/15/16].
    32. Cali I, Miller CJ, Parisi JE, Geschwind M, Gambetti P, Schonberger LB. Distinct pathological phenotypes of Creutzfeldt-Jakob disease in recipients of prion-contaminated growth hormone. Acta Neuropathol Commun. 2015 Jun 25; 3:37. PMID: 26108478; PMCID: PMC4479081.
    33. Kim MO, Geschwind M. Clinical update of Jakob-Creutzfeldt disease. Curr Opin Neurol. 2015 Jun; 28(3):302-10. PMID: 25923128.
      View in: PubMed
    34. Höftberger R, van Sonderen A, Leypoldt F, Houghton D, Geschwind M, Gelfand J, Paredes M, Sabater L, Saiz A, Titulaer MJ, Graus F, Dalmau J. Encephalitis and AMPA receptor antibodies: Novel findings in a case series of 22 patients. Neurology. 2015 Jun 16; 84(24):2403-12. PMID: 25979696; PMCID: PMC4478035.
    35. Rosenbloom MH, Tartaglia MC, Forner SA, Wong KK, Kuo A, Johnson DY, Colacurcio V, Andrews BD, Miller BL, DeArmond SJ, Geschwind M. Metabolic disorders with clinical and radiologic features of sporadic Creutzfeldt-Jakob disease. Neurol Clin Pract. 2015 Apr; 5(2):108-115. PMID: 26137419.
      View in: PubMed
    36. Forner SA, Takada LT, Bettcher BM, Lobach IV, Tartaglia MC, Torres-Chae C, Haman A, Thai J, Vitali P, Neuhaus J, Bostrom A, Miller BL, Rosen HJ, Geschwind M. Comparing CSF biomarkers and brain MRI in the diagnosis of sporadic Creutzfeldt-Jakob disease. Neurol Clin Pract. 2015 Apr; 5(2):116-125. PMID: 26137420.
      View in: PubMed
    37. Irani SR, Lehmann-Horn K, Geschwind M, Wang S, Vincent A, von Büdingen HC. The active intrathecal B-cell response in LGI1-antibody encephalitis. Lancet. 2015 Feb 26; 385 Suppl 1:S46. PMID: 26312868.
      View in: PubMed
    38. Lo RY, Figueroa KP, Pulst SM, Lin CY, Perlman S, Wilmot G, Gomez CM, Schmahmann J, Paulson H, Shakkottai VG, Ying SH, Zesiewicz T, Bushara K, Geschwind M, Xia G, Subramony SH, Ashizawa T, Kuo SH. Vascular risk factors and clinical progression in spinocerebellar ataxias. Tremor Other Hyperkinet Mov (N Y). 2015; 5:287. PMID: 25713748; PMCID: PMC4314609.
    39. Hurth K, Tarawneh R, Ghoshal N, Benzinger TLS, Clifford DB, Geschwind M, Morris JC, Galvin JE, Schmidt RE, Cairns NJ. Whipple's disease masquerades as dementia with Lewy bodies. Alzheimer Dis Assoc Disord. 2015 Jan-Mar; 29(1):85-89. PMID: 23995819; PMCID: PMC3938990.
    40. Lo RY, Figueroa KP, Pulst SM, Lin CY, Perlman S, Wilmot G, Gomez C, Schmahmann J, Paulson H, Shakkottai VG, Ying S, Zesiewicz T, Bushara K, Geschwind M, Xia G, Subramony SH, Ashizawa T, Kuo SH. Coenzyme Q10 and spinocerebellar ataxias. Mov Disord. 2015 Feb; 30(2):214-20. PMID: 25449974; PMCID: PMC4674072.
    41. Caverzasi E, Mandelli ML, DeArmond SJ, Hess CP, Vitali P, Papinutto N, Oehler A, Miller BL, Lobach IV, Bastianello S, Geschwind M, Henry RG. White matter involvement in sporadic Creutzfeldt-Jakob disease. Brain. 2014 Dec; 137(Pt 12):3339-54. PMID: 25367029; PMCID: PMC4240303.
    42. Minikel EV, Zerr I, Collins SJ, Ponto C, Boyd A, Klug G, Karch A, Kenny J, Collinge J, Takada LT, Forner S, Fong JC, Mead S, Geschwind M. Ascertainment bias causes false signal of anticipation in genetic prion disease. Am J Hum Genet. 2014 Oct 02; 95(4):371-82. PMID: 25279981; PMCID: PMC4185115.
    43. Naasan G, Irani SR, Bettcher BM, Geschwind M, Gelfand JM. Episodic bradycardia as neurocardiac prodrome to voltage-gated potassium channel complex/leucine-rich, glioma inactivated 1 antibody encephalitis. JAMA Neurol. 2014 Oct; 71(10):1300-4. PMID: 25133690; PMCID: PMC4474144.
    44. Zhang X, Lee SJ, Young KZ, Josephson DA, Geschwind M, Wang MM. Latent NOTCH3 epitopes unmasked in CADASIL and regulated by protein redox state. Brain Res. 2014 Oct 02; 1583:230-6. PMID: 25150590; PMCID: PMC4206828.
    45. Irani SR, Gelfand JM, Bettcher BM, Singhal NS, Geschwind M. Effect of rituximab in patients with leucine-rich, glioma-inactivated 1 antibody-associated encephalopathy. JAMA Neurol. 2014 Jul 01; 71(7):896-900. PMID: 24842754; PMCID: PMC4477824.
    46. Uflacker A, Doraiswamy PM, Rechitsky S, See T, Geschwind M, Tur-Kaspa I. Preimplantation genetic diagnosis (PGD) for genetic prion disorder due to F198S mutation in the PRNP gene. JAMA Neurol. 2014 Apr; 71(4):484-6. PMID: 24493558; PMCID: PMC4349573.
    47. Li Y, Chen JA, Sears RL, Gao F, Klein ED, Karydas A, Geschwind M, Rosen HJ, Boxer AL, Guo W, Pellegrini M, Horvath S, Miller BL, Geschwind DH, Coppola G. An epigenetic signature in peripheral blood associated with the haplotype on 17q21.31, a risk factor for neurodegenerative tauopathy. PLoS Genet. 2014 Mar; 10(3):e1004211. PMID: 24603599; PMCID: PMC3945475.
    48. Geschwind M. Doxycycline for Creutzfeldt-Jakob disease: a failure, but a step in the right direction. Lancet Neurol. 2014 Feb; 13(2):130-2. PMID: 24411710.
      View in: PubMed
    49. You SC, Geschwind M, Sha SJ, Apple A, Satris G, Wood KA, Johnson ET, Gooblar J, Feuerstein JS, Finkbeiner S, Kang GA, Miller BL, Hess CP, Kramer JH, Possin KL. Executive functions in premanifest Huntington's disease. Mov Disord. 2014 Mar; 29(3):405-9. PMID: 24375511; PMCID: PMC4029327.
    50. Kim MO, Cali I, Oehler A, Fong JC, Wong K, See T, Katz JS, Gambetti P, Bettcher BM, Dearmond SJ, Geschwind M. Genetic CJD with a novel E200G mutation in the prion protein gene and comparison with E200K mutation cases. Acta Neuropathol Commun. 2013 Dec 12; 1:80. PMID: 24330864; PMCID: PMC3880091.
    51. Takada LT, Geschwind M. Prion diseases. Semin Neurol. 2013 Sep; 33(4):348-56. PMID: 24234356.
      View in: PubMed
    52. Ashizawa T, Figueroa KP, Perlman SL, Gomez CM, Wilmot GR, Schmahmann JD, Ying SH, Zesiewicz TA, Paulson HL, Shakkottai VG, Bushara KO, Kuo SH, Geschwind M, Xia G, Mazzoni P, Krischer JP, Cuthbertson D, Holbert AR, Ferguson JH, Pulst SM, Subramony SH. Clinical characteristics of patients with spinocerebellar ataxias 1, 2, 3 and 6 in the US; a prospective observational study. Orphanet J Rare Dis. 2013 Nov 13; 8:177. PMID: 24225362; PMCID: PMC3843578.
    53. Geschwind M, Kuo AL, Wong KS, Haman A, Devereux G, Raudabaugh BJ, Johnson DY, Torres-Chae CC, Finley R, Garcia P, Thai JN, Cheng HQ, Neuhaus JM, Forner SA, Duncan JL, Possin KL, Dearmond SJ, Prusiner SB, Miller BL. Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease. Neurology. 2013 Dec 03; 81(23):2015-23. PMID: 24122181; PMCID: PMC4211922.
    54. Lee SE, Tartaglia MC, Yener G, Genç S, Seeley WW, Sanchez-Juan P, Moreno F, Mendez MF, Klein E, Rademakers R, López de Munain A, Combarros O, Kramer JH, Kenet RO, Boxer AL, Geschwind M, Gorno-Tempini ML, Karydas AM, Rabinovici GD, Coppola G, Geschwind DH, Miller BL. Neurodegenerative disease phenotypes in carriers of MAPT p.A152T, a risk factor for frontotemporal dementia spectrum disorders and Alzheimer disease. Alzheimer Dis Assoc Disord. 2013 Oct-Dec; 27(4):302-9. PMID: 23518664; PMCID: PMC3796183.
    55. Vossel KA, Beagle AJ, Rabinovici GD, Shu H, Lee SE, Naasan G, Hegde M, Cornes SB, Henry ML, Nelson AB, Seeley WW, Geschwind M, Gorno-Tempini ML, Shih T, Kirsch HE, Garcia PA, Miller BL, Mucke L. Seizures and epileptiform activity in the early stages of Alzheimer disease. JAMA Neurol. 2013 Sep 01; 70(9):1158-66. PMID: 23835471; PMCID: PMC4013391.
    56. Bechtel K, Geschwind M. Ethics in prion disease. Prog Neurobiol. 2013 Nov; 110:29-44. PMID: 23906487; PMCID: PMC3818451.
    57. Biglan KM, Zhang Y, Long JD, Geschwind M, Kang GA, Killoran A, Lu W, McCusker E, Mills JA, Raymond LA, Testa C, Wojcieszek J, Paulsen JS. Refining the diagnosis of Huntington disease: the PREDICT-HD study. Front Aging Neurosci. 2013; 5:12. PMID: 23565093; PMCID: PMC3613616.
    58. Johnson DY, Dunkelberger DL, Henry M, Haman A, Greicius MD, Wong K, DeArmond SJ, Miller BL, Gorno-Tempini ML, Geschwind M. Sporadic Jakob-Creutzfeldt disease presenting as primary progressive aphasia. JAMA Neurol. 2013 Feb; 70(2):254-7. PMID: 23400721; PMCID: PMC4365870.
    59. Paterson RW, Torres-Chae CC, Kuo AL, Ando T, Nguyen EA, Wong K, DeArmond SJ, Haman A, Garcia P, Johnson DY, Miller BL, Geschwind M. Differential diagnosis of Jakob-Creutzfeldt disease. Arch Neurol. 2012 Dec; 69(12):1578-82. PMID: 23229042; PMCID: PMC4401069.
    60. Almeida S, Zhang Z, Coppola G, Mao W, Futai K, Karydas A, Geschwind M, Tartaglia MC, Gao F, Gianni D, Sena-Esteves M, Geschwind DH, Miller BL, Farese RV, Gao FB. Induced pluripotent stem cell models of progranulin-deficient frontotemporal dementia uncover specific reversible neuronal defects. Cell Rep. 2012 Oct 25; 2(4):789-98. PMID: 23063362; PMCID: PMC3532907.
    61. Paterson RW, Takada LT, Geschwind M. Diagnosis and treatment of rapidly progressive dementias. Neurol Clin Pract. 2012 Sep; 2(3):187-200. PMID: 23634367.
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    62. Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, Cotman CW, Decarli CS, Levey AI, Ringman JM, Mendez MF, Chui HC, Le Ber I, Brice A, Lupton MK, Preza E, Lovestone S, Powell J, Graff-Radford N, Petersen RC, Boeve BF, Lippa CF, Bigio EH, Mackenzie I, Finger E, Kertesz A, Caselli RJ, Gearing M, Juncos JL, Ghetti B, Spina S, Bordelon YM, Tourtellotte WW, Frosch MP, Vonsattel JP, Zarow C, Beach TG, Albin RL, Lieberman AP, Lee VM, Trojanowski JQ, Van Deerlin VM, Bird TD, Galasko DR, Masliah E, White CL, Troncoso JC, Hannequin D, Boxer AL, Geschwind M, Kumar S, Mandelkow EM, Wszolek ZK, Uitti RJ, Dickson DW, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Hum Mol Genet. 2012 Aug 01; 21(15):3500-12. PMID: 22556362.
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    63. Tartaglia MC, Johnson DY, Thai JN, Cattaruzza T, Wong K, Garcia P, Dearmond SJ, Miller BL, Geschwind M. Clinical overlap between Jakob-Creutzfeldt disease and Lewy body disease. Can J Neurol Sci. 2012 May; 39(3):304-10. PMID: 22547509; PMCID: PMC3590309.
    64. Perry DC, Geschwind M. Thorough work-up and new diagnostic criteria needed for CJD. Nat Rev Neurol. 2011 Sep 05; 7(9):479-80. PMID: 21892213; PMCID: PMC4134013.
    65. Sloan JL, Johnston JJ, Manoli I, Chandler RJ, Krause C, Carrillo-Carrasco N, Chandrasekaran SD, Sysol JR, O'Brien K, Hauser NS, Sapp JC, Dorward HM, Huizing M. Exome sequencing identifies ACSF3 as a cause of combined malonic and methylmalonic aciduria. Nat Genet. 2011 Aug 14; 43(9):883-6. PMID: 21841779.
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    66. Lee SE, Rabinovici GD, Mayo MC, Wilson SM, Seeley WW, DeArmond SJ, Huang EJ, Trojanowski JQ, Growdon ME, Jang JY, Sidhu M, See TM, Karydas AM, Gorno-Tempini ML, Boxer AL, Weiner MW, Geschwind M, Rankin KP, Miller BL. Clinicopathological correlations in corticobasal degeneration. Ann Neurol. 2011 Aug; 70(2):327-40. PMID: 21823158; PMCID: PMC3154081.
    67. Tartaglia MC, Thai JN, See T, Kuo A, Harbaugh R, Raudabaugh B, Cali I, Sattavat M, Sanchez H, DeArmond SJ, Geschwind M. Pathologic evidence that the T188R mutation in PRNP is associated with prion disease. J Neuropathol Exp Neurol. 2010 Dec; 69(12):1220-7. PMID: 21107135; PMCID: PMC3136530.
    68. Zou WQ, Puoti G, Xiao X, Yuan J, Qing L, Cali I, Shimoji M, Langeveld JP, Castellani R, Notari S, Crain B, Schmidt RE, Geschwind M, Dearmond SJ, Cairns NJ, Dickson D, Honig L, Torres JM, Mastrianni J, Capellari S, Giaccone G, Belay ED, Schonberger LB, Cohen M, Perry G, Kong Q, Parchi P, Tagliavini F, Gambetti P. Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein. Ann Neurol. 2010 Aug; 68(2):162-72. PMID: 20695009; PMCID: PMC3032610.
    69. Benetti F, Geschwind M, Legname G. De novo prions. F1000 Biol Rep. 2010 Jun 23; 2. PMID: 20948787; PMCID: PMC2950034.
    70. Yang TI, Jung DS, Ahn BY, Jeong BH, Cho HJ, Kim YS, Na DL, Geschwind M, Kim EJ. Familial Creutzfeldt-Jakob disease with V180I mutation. J Korean Med Sci. 2010 Jul; 25(7):1097-100. PMID: 20592908; PMCID: PMC2890893.
    71. Geschwind M. Are you related to "the Geschwind?". Neuropsychol Rev. 2010 Jun; 20(2):123-5. PMID: 20512417; PMCID: PMC2881317.
    72. Geschwind M. Rapidly progressive dementia: prion diseases and other rapid dementias. Continuum (Minneap Minn). 2010 Apr; 16(2 Dementia):31-56. PMID: 22810280.
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    73. Kieburtz K, McDermott MP, Voss TS, Corey-Bloom J, Deuel LM, Dorsey ER, Factor S, Geschwind M, Hodgeman K, Kayson E, Noonberg S, Pourfar M, Rabinowitz K, Ravina B, Sanchez-Ramos J, Seely L, Walker F, Feigin A. A randomized, placebo-controlled trial of latrepirdine in Huntington disease. Arch Neurol. 2010 Feb; 67(2):154-60. PMID: 20142523; PMCID: PMC4134015.
    74. Barajas RF, Collins DE, Cha S, Geschwind M. Adult-onset drug-refractory seizure disorder associated with anti-voltage-gated potassium-channel antibody. Epilepsia. 2010 Mar; 51(3):473-7. PMID: 19780798; PMCID: PMC2907153.
    75. Rosenbloom MH, Smith S, Akdal G, Geschwind M. Immunologically mediated dementias. Curr Neurol Neurosci Rep. 2009 Sep; 9(5):359-67. PMID: 19664365; PMCID: PMC2832614.
    76. Choi EM, Geschwind M, Deering C, Pomeroy K, Kuo A, Miller BL, Safar JG, Prusiner SB. Prion proteins in subpopulations of white blood cells from patients with sporadic Creutzfeldt-Jakob disease. Lab Invest. 2009 Jun; 89(6):624-35. PMID: 19434060; PMCID: PMC2786774.
    77. Lai M, Hughes EG, Peng X, Zhou L, Gleichman AJ, Shu H, Matà S, Kremens D, Vitaliani R, Geschwind M, Bataller L, Kalb RG, Davis R, Graus F, Lynch DR, Balice-Gordon R, Dalmau J. AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location. Ann Neurol. 2009 Apr; 65(4):424-34. PMID: 19338055; PMCID: PMC2677127.
    78. Geschwind M. Clinical trials for prion disease: difficult challenges, but hope for the future. Lancet Neurol. 2009 Apr; 8(4):304-6. PMID: 19278901; PMCID: PMC2757050.
    79. Geschwind M, Potter CA, Sattavat M, Garcia PA, Rosen HJ, Miller BL, DeArmond SJ. Correlating DWI MRI with pathologic and other features of Jakob-Creutzfeldt disease. Alzheimer Dis Assoc Disord. 2009 Jan-Mar; 23(1):82-87. PMID: 19266702; PMCID: PMC2684989.
    80. Vitali P, Migliaccio R, Agosta F, Rosen HJ, Geschwind M. Neuroimaging in dementia. Semin Neurol. 2008 Sep; 28(4):467-83. PMID: 18843575; PMCID: PMC2647854.
    81. Geschwind M, Tan KM, Lennon VA, Barajas RF, Haman A, Klein CJ, Josephson SA, Pittock SJ. Voltage-gated potassium channel autoimmunity mimicking creutzfeldt-jakob disease. Arch Neurol. 2008 Oct; 65(10):1341-6. PMID: 18852349; PMCID: PMC2736144.
    82. Maddox RA, Belay ED, Curns AT, Zou WQ, Nowicki S, Lembach RG, Geschwind M, Haman A, Shinozaki N, Nakamura Y, Borer MJ, Schonberger LB. Creutzfeldt-Jakob disease in recipients of corneal transplants. Cornea. 2008 Aug; 27(7):851-4. PMID: 18650677.
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    83. Geschwind M, Shu H, Haman A, Sejvar JJ, Miller BL. Rapidly progressive dementia. Ann Neurol. 2008 Jul; 64(1):97-108. PMID: 18668637; PMCID: PMC2647859.
    84. Valcour V, Haman A, Cornes S, Lawall C, Parsa AT, Glaser C, Yagi S, Tihan T, Bhatnagar J, Geschwind M. A case of enteroviral meningoencephalitis presenting as rapidly progressive dementia. Nat Clin Pract Neurol. 2008 Jul; 4(7):399-403. PMID: 18477991; PMCID: PMC2637149.
    85. Geschwind M, Josephs KA, Parisi JE, Keegan BM. A 54-year-old man with slowness of movement and confusion. Neurology. 2007 Nov 06; 69(19):1881-7. PMID: 17984457; PMCID: PMC2637148.
    86. Geschwind M, Haman A, Miller BL. Rapidly progressive dementia. Neurol Clin. 2007 Aug; 25(3):783-807, vii. PMID: 17659190; PMCID: PMC2706263.
    87. Vernino S, Geschwind M, Boeve B. Autoimmune encephalopathies. Neurologist. 2007 May; 13(3):140-7. PMID: 17495758.
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    88. Josephson SA, Papanastassiou AM, Berger MS, Barbaro NM, McDermott MW, Hilton JF, Miller BL, Geschwind M. The diagnostic utility of brain biopsy procedures in patients with rapidly deteriorating neurological conditions or dementia. J Neurosurg. 2007 Jan; 106(1):72-5. PMID: 17236490.
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    89. Safar JG, Wille H, Geschwind M, Deering C, Latawiec D, Serban A, King DJ, Legname G, Weisgraber KH, Mahley RW, Miller BL, Dearmond SJ, Prusiner SB. Human prions and plasma lipoproteins. Proc Natl Acad Sci U S A. 2006 Jul 25; 103(30):11312-7. PMID: 16849426; PMCID: PMC1544083.
    90. Chang CC, Eggers SD, Johnson JK, Haman A, Miller BL, Geschwind M. Anti-GAD antibody cerebellar ataxia mimicking Creutzfeldt-Jakob disease. Clin Neurol Neurosurg. 2007 Jan; 109(1):54-7. PMID: 16621241.
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    91. Lewis AM, Yu M, DeArmond SJ, Dillon WP, Miller BL, Geschwind M. Human growth hormone-related iatrogenic Creutzfeldt-Jakob disease with abnormal imaging. Arch Neurol. 2006 Feb; 63(2):288-90. PMID: 16476821.
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    92. Boxer AL, Geschwind M, Belfor N, Gorno-Tempini ML, Schauer GF, Miller BL, Weiner MW, Rosen HJ. Patterns of brain atrophy that differentiate corticobasal degeneration syndrome from progressive supranuclear palsy. Arch Neurol. 2006 Jan; 63(1):81-6. PMID: 16401739.
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    93. Young GS, Geschwind M, Fischbein NJ, Martindale JL, Henry RG, Liu S, Lu Y, Wong S, Liu H, Miller BL, Dillon WP. Diffusion-weighted and fluid-attenuated inversion recovery imaging in Creutzfeldt-Jakob disease: high sensitivity and specificity for diagnosis. AJNR Am J Neuroradiol. 2005 Jun-Jul; 26(6):1551-62. PMID: 15956529.
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    94. Safar JG, Geschwind M, Deering C, Didorenko S, Sattavat M, Sanchez H, Serban A, Vey M, Baron H, Giles K, Miller BL, Dearmond SJ, Prusiner SB. Diagnosis of human prion disease. Proc Natl Acad Sci U S A. 2005 Mar 01; 102(9):3501-6. PMID: 15741275; PMCID: PMC552933.
    95. Goldman JS, Miller BL, Safar J, de Tourreil S, Martindale JL, Prusiner SB, Geschwind M. When sporadic disease is not sporadic: the potential for genetic etiology. Arch Neurol. 2004 Feb; 61(2):213-6. PMID: 14967768.
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    96. Geschwind M, Martindale J, Miller D, DeArmond SJ, Uyehara-Lock J, Gaskin D, Kramer JH, Barbaro NM, Miller BL. Challenging the clinical utility of the 14-3-3 protein for the diagnosis of sporadic Creutzfeldt-Jakob disease. Arch Neurol. 2003 Jun; 60(6):813-6. PMID: 12810484.
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    97. Martindale JL, Geschwind M, Miller BL. Psychiatric and neuroimaging findings in Creutzfeldt-Jakob disease. Curr Psychiatry Rep. 2003 May; 5(1):43-6. PMID: 12686001.
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    98. Martindale J, Geschwind M, De Armond S, Young G, Dillon WP, Henry R, Uyehara-Lock JH, Gaskin DA, Miller BL. Sporadic Creutzfeldt-Jakob disease mimicking variant Creutzfeldt-Jakob disease. Arch Neurol. 2003 May; 60(5):767-70. PMID: 12756143.
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