Julio Rojas, MD, PhD

Title(s)Associate Professor, Neurology
SchoolSchool of Medicine
Address1651 4th Street, #411G
San Francisco CA 94158
ORCID ORCID Icon0000-0002-1308-646X Additional info
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoFellowship2017Behavioral Neurology
    Univesity of Texas Southwestern Medical CenterNeurology2014Department of Neurology & Neurotherapeutics
    University of Texas at AustinPhD2010Institute for Neuroscience
    Tecnologico de Monterrey, ITESMMD2003Escuela de Medicina

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Proteomics for fluid biomarker discovery in frontotemporal dementia
    NIH K23AG059888Apr 1, 2019 - Mar 31, 2024
    Role: Principal Investigator

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    Collapse Clinical Trials
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Presence of Preoperative Neurodegeneration Biofluid Markers in Patients with Postoperative Delirium. Anesthesiology. 2023 10 01; 139(4):432-443. Leung JM, Rojas JC, Tang C, Chan B, Lario-Lago A, Boxer AL, Do Q, Kramer JH, Du Z, Du P, Sands LP, Perioperative Medicine Research Group. PMID: 37364279; PMCID: PMC10529495.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Head-to-head comparison between plasma p-tau217 and flortaucipir-PET in amyloid-positive patients with cognitive impairment. Alzheimers Res Ther. 2023 09 22; 15(1):157. Mundada NS, Rojas JC, Vandevrede L, Thijssen EH, Iaccarino L, Okoye OC, Shankar R, Soleimani-Meigooni DN, Lago AL, Miller BL, Teunissen CE, Heuer H, Rosen HJ, Dage JL, Jagust WJ, Rabinovici GD, Boxer AL, La Joie R. PMID: 37740209; PMCID: PMC10517500.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Co-pathology may impact outcomes of amyloid-targeting treatments: clinicopathological results from two patients treated with aducanumab. Acta Neuropathol. 2023 11; 146(5):777-781. VandeVrede L, La Joie R, Horiki S, Mundada NS, Koestler M, Hwang JH, Ljubenkov PA, Rojas JC, Rabinovici GD, Boxer AL, Seeley WW. PMID: 37725166; PMCID: PMC10564667.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. Anti-Amyloid Immunotherapies for Alzheimer's Disease: A 2023 Clinical Update. Neurotherapeutics. 2023 07; 20(4):914-931. Yadollahikhales G, Rojas JC. PMID: 37490245; PMCID: PMC10457266.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    5. Alzheimer's pathology is associated with altered cognition, brain volume, and plasma biomarker patterns in traumatic encephalopathy syndrome. Alzheimers Res Ther. 2023 07 21; 15(1):126. Asken BM, Tanner JA, Gaynor LS, VandeVrede L, Mantyh WG, Casaletto KB, Staffaroni AM, Fonseca C, Shankar R, Grant H, Smith K, Lago AL, Xu H, La Joie R, Cobigo Y, Rosen H, Perry DC, Rojas JC, Miller BL, Gardner RC, Wang KKW, Kramer JH, Rabinovici GD. PMID: 37480088; PMCID: PMC10360257.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. A call to address structural barriers to Hispanic/Latino representation in clinical trials on Alzheimer's disease and related dementias: A micro-meso-macro perspective. Alzheimers Dement (N Y). 2023 Apr-Jun; 9(2):e12389. Aranda MP, Marquez DX, Gallagher-Thompson D, Pérez A, Rojas JC, Hill CV, Reyes Y, Dilworth-Anderson P, Portacolone E. PMID: 37287471; PMCID: PMC10242183.
      View in: PubMed   Mentions: 5  
    7. Feasibility and acceptability of remote smartphone cognitive testing in frontotemporal dementia research. Alzheimers Dement (Amst). 2023 Apr-Jun; 15(2):e12423. Taylor JC, Heuer HW, Clark AL, Wise AB, Manoochehri M, Forsberg L, Mester C, Rao M, Brushaber D, Kramer J, Welch AE, Kornak J, Kremers W, Appleby B, Dickerson BC, Domoto-Reilly K, Fields JA, Ghoshal N, Graff-Radford N, Grossman M, Hall MG, Huey ED, Irwin D, Lapid MI, Litvan I, Mackenzie IR, Masdeu JC, Mendez MF, Nevler N, Onyike CU, Pascual B, Pressman P, Rankin KP, Ratnasiri B, Rojas JC, Tartaglia MC, Wong B, Gorno-Tempini ML, Boeve BF, Rosen HJ, Boxer AL, Staffaroni AM. PMID: 37180971; PMCID: PMC10170087.
      View in: PubMed   Mentions: 1  
    8. Evaluation of Plasma Phosphorylated Tau217 for Differentiation Between Alzheimer Disease and Frontotemporal Lobar Degeneration Subtypes Among Patients With Corticobasal Syndrome. JAMA Neurol. 2023 05 01; 80(5):495-505. VandeVrede L, La Joie R, Thijssen EH, Asken BM, Vento SA, Tsuei T, Baker SL, Cobigo Y, Fonseca C, Heuer HW, Kramer JH, Ljubenkov PA, Rabinovici GD, Rojas JC, Rosen HJ, Staffaroni AM, Boeve BF, Dickerson BC, Grossman M, Huey ED, Irwin DJ, Litvan I, Pantelyat AY, Tartaglia MC, Dage JL, Boxer AL. PMID: 37010841; PMCID: PMC10071401.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Gamma neuromodulation improves episodic memory and its associated network in amnestic mild cognitive impairment: a pilot study. Neurobiol Aging. 2023 09; 129:72-88. Jones KT, Gallen CL, Ostrand AE, Rojas JC, Wais P, Rini J, Chan B, Lago AL, Boxer A, Zhao M, Gazzaley A, Zanto TP. PMID: 37276822; PMCID: PMC10583532.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Blood Biomarkers in Neurodegenerative Diseases: Implications for the Clinical Neurologist. Neurology. 2023 07 25; 101(4):172-180. Alcolea D, Beeri MS, Rojas JC, Gardner RC, Lleó A. PMID: 36878698; PMCID: PMC10435056.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    11. Multisite ALLFTD study modeling progressive empathy loss from the earliest stages of behavioral variant frontotemporal dementia. Alzheimers Dement. 2023 07; 19(7):2842-2852. Toller G, Cobigo Y, Callahan P, Appleby BS, Brushaber D, Domoto-Reilly K, Forsberg LK, Ghoshal N, Graff-Radford J, Graff-Radford NR, Grossman M, Heuer HW, Kornak J, Kremers W, Lapid MI, Leger G, Litvan I, Mackenzie IR, Pascual MB, Ramos EM, Rascovsky K, Rojas JC, Staffaroni AM, Tartaglia MC, Toga A, Weintraub S, Wszolek ZK, Boeve BF, Boxer AL, Rosen HJ, Rankin KP, ALLFTD consortium. PMID: 36591730; PMCID: PMC10314956.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Association of Physical Activity With Neurofilament Light Chain Trajectories in Autosomal Dominant Frontotemporal Lobar Degeneration Variant Carriers. JAMA Neurol. 2023 01 01; 80(1):82-90. Casaletto KB, Kornack J, Paolillo EW, Rojas JC, VandeBunte A, Staffaroni AS, Lee S, Heuer H, Forsberg L, Ramos EM, Miller BL, Kramer JH, Yaffe K, Petrucelli L, Boxer A, Boeve B, Gendron TF, Rosen H, ALLFTD Consortium. PMID: 36374516; PMCID: PMC9664369.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    13. Temporal order of clinical and biomarker changes in familial frontotemporal dementia. Nat Med. 2022 10; 28(10):2194-2206. Staffaroni AM, Quintana M, Wendelberger B, Heuer HW, Russell LL, Cobigo Y, Wolf A, Goh SM, Petrucelli L, Gendron TF, Heller C, Clark AL, Taylor JC, Wise A, Ong E, Forsberg L, Brushaber D, Rojas JC, VandeVrede L, Ljubenkov P, Kramer J, Casaletto KB, Appleby B, Bordelon Y, Botha H, Dickerson BC, Domoto-Reilly K, Fields JA, Foroud T, Gavrilova R, Geschwind D, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grossman M, Hall MGH, Hsiung GY, Huey ED, Irwin D, Jones DT, Kantarci K, Kaufer D, Knopman D, Kremers W, Lago AL, Lapid MI, Litvan I, Lucente D, Mackenzie IR, Mendez MF, Mester C, Miller BL, Onyike CU, Rademakers R, Ramanan VK, Ramos EM, Rao M, Rascovsky K, Rankin KP, Roberson ED, Savica R, Tartaglia MC, Weintraub S, Wong B, Cash DM, Bouzigues A, Swift IJ, Peakman G, Bocchetta M, Todd EG, Convery RS, Rowe JB, Borroni B, Galimberti D, Tiraboschi P, Masellis M, Finger E, van Swieten JC, Seelaar H, Jiskoot LC, Sorbi S, Butler CR, Graff C, Gerhard A, Langheinrich T, Laforce R, Sanchez-Valle R, de Mendonça A, Moreno F, Synofzik M, Vandenberghe R, Ducharme S, Le Ber I, Levin J, Danek A, Otto M, Pasquier F, Santana I, Kornak J, Boeve BF, Rosen HJ, Rohrer JD, Boxer AL, Frontotemporal Dementia Prevention Initiative (FPI) Investigators. PMID: 36138153; PMCID: PMC9951811.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    14. Sensitivity of the Social Behavior Observer Checklist to Early Symptoms of Patients With Frontotemporal Dementia. Neurology. 2022 Aug 01; 99(5):e488-e499. Toller G, Cobigo Y, Ljubenkov PA, Appleby BS, Dickerson BC, Domoto-Reilly K, Fong JC, Forsberg LK, Gavrilova RH, Ghoshal N, Heuer HW, Knopman DS, Kornak J, Lapid MI, Litvan I, Lucente DE, Mackenzie IR, McGinnis SM, Miller BL, Pedraza O, Rojas JC, Staffaroni AM, Wong B, Wszolek ZK, Boeve BF, Boxer AL, Rosen HJ, Rankin KP, and the ALLFTD research consortium. PMID: 35584922; PMCID: PMC9421596.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Hepatic and renal function impact concentrations of plasma biomarkers of neuropathology. Alzheimers Dement (Amst). 2022; 14(1):e12321. Berry K, Asken BM, Grab JD, Chan B, Lario Lago A, Wong R, Seetharaman S, LaHue SC, Possin KL, Rojas JC, Kramer JH, Boxer AL, Lai JC, VandeVrede L. PMID: 35845260; PMCID: PMC9274803.
      View in: PubMed   Mentions: 10  
    16. Plasma neurofilament light chain levels suggest neuroaxonal stability following therapeutic remyelination in people with multiple sclerosis. J Neurol Neurosurg Psychiatry. 2022 Jun 16. Abdelhak A, Cordano C, Boscardin WJ, Caverzasi E, Kuhle J, Chan B, Gelfand JM, Yiu HH, Oertel FC, Beaudry-Richard A, Condor Montes S, Oksenberg JR, Lario Lago A, Boxer A, Rojas-Martinez JC, Elahi FM, Chan JR, Green AJ. PMID: 35710320; PMCID: PMC9984688.
      View in: PubMed   Mentions: 3     Fields:    
    17. Visual Impairment as a Modifiable Risk Factor in Dementia Prevention and Management. JAMA Neurol. 2022 06 01; 79(6):542-543. Deal J, Rojas JC. PMID: 35467705; PMCID: PMC9949617.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Plasma P-tau181 and P-tau217 in Patients With Traumatic Encephalopathy Syndrome With and Without Evidence of Alzheimer Disease Pathology. Neurology. 2022 08 09; 99(6):e594-e604. Asken BM, Tanner JA, VandeVrede L, Mantyh WG, Casaletto KB, Staffaroni AM, La Joie R, Iaccarino L, Soleimani-Meigooni D, Rojas JC, Gardner RC, Miller BL, Grinberg LT, Boxer AL, Kramer JH, Rabinovici GD. PMID: 35577574; PMCID: PMC9442622.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    19. Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disorders. Cell Rep Med. 2022 04 19; 3(4):100607. Gendron TF, Heckman MG, White LJ, Veire AM, Pedraza O, Burch AR, Bozoki AC, Dickerson BC, Domoto-Reilly K, Foroud T, Forsberg LK, Galasko DR, Ghoshal N, Graff-Radford NR, Grossman M, Heuer HW, Huey ED, Hsiung GR, Irwin DJ, Kaufer DI, Leger GC, Litvan I, Masdeu JC, Mendez MF, Onyike CU, Pascual B, Ritter A, Roberson ED, Rojas JC, Tartaglia MC, Wszolek ZK, Rosen H, Boeve BF, Boxer AL, ALLFTD consortium, Petrucelli L. PMID: 35492244; PMCID: PMC9044101.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    20. Diagnostic Accuracy of Magnetic Resonance Imaging Measures of Brain Atrophy Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Degeneration. JAMA Netw Open. 2022 04 01; 5(4):e229588. Illán-Gala I, Nigro S, VandeVrede L, Falgàs N, Heuer HW, Painous C, Compta Y, Martí MJ, Montal V, Pagonabarraga J, Kulisevsky J, Lleó A, Fortea J, Logroscino G, Quattrone A, Quattrone A, Perry DC, Gorno-Tempini ML, Rosen HJ, Grinberg LT, Spina S, La Joie R, Rabinovici GD, Miller BL, Rojas JC, Seeley WW, Boxer AL. PMID: 35486397; PMCID: PMC9055455.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    21. Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic performance study. Lancet Neurol. 2021 09; 20(9):739-752. Thijssen EH, La Joie R, Strom A, Fonseca C, Iaccarino L, Wolf A, Spina S, Allen IE, Cobigo Y, Heuer H, VandeVrede L, Proctor NK, Lago AL, Baker S, Sivasankaran R, Kieloch A, Kinhikar A, Yu L, Valentin MA, Jeromin A, Zetterberg H, Hansson O, Mattsson-Carlgren N, Graham D, Blennow K, Kramer JH, Grinberg LT, Seeley WW, Rosen H, Boeve BF, Miller BL, Teunissen CE, Rabinovici GD, Rojas JC, Dage JL, Boxer AL, Advancing Research and Treatment for Frontotemporal Lobar Degeneration investigators. PMID: 34418401; PMCID: PMC8711249.
      View in: PubMed   Mentions: 127     Fields:    
    22. Effect of the Histone Deacetylase Inhibitor FRM-0334 on Progranulin Levels in Patients With Progranulin Gene Haploinsufficiency: A Randomized Clinical Trial. JAMA Netw Open. 2021 09 01; 4(9):e2125584. Ljubenkov PA, Edwards L, Iaccarino L, La Joie R, Rojas JC, Koestler M, Harris B, Boeve BF, Borroni B, van Swieten JC, Grossman M, Pasquier F, Frisoni GB, Mummery CJ, Vandenberghe R, Le Ber I, Hannequin D, McGinnis SM, Auriacombe S, Onofrj M, Goodman IJ, Riordan HJ, Wisniewski G, Hesterman J, Marek K, Haynes BA, Patzke H, Koenig G, Hilt D, Moebius H, Boxer AL. PMID: 34559230; PMCID: PMC8463943.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    23. Lower White Matter Volume and Worse Executive Functioning Reflected in Higher Levels of Plasma GFAP among Older Adults with and Without Cognitive Impairment. J Int Neuropsychol Soc. 2022 07; 28(6):588-599. Asken BM, VandeVrede L, Rojas JC, Fonseca C, Staffaroni AM, Elahi FM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Boxer AL, Miller BL, Rosen HJ, Kramer JH, Casaletto KB. PMID: 34158138; PMCID: PMC8692495.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    24. Selective vulnerability to atrophy in sporadic Creutzfeldt-Jakob disease. Ann Clin Transl Neurol. 2021 06; 8(6):1183-1199. Younes K, Rojas JC, Wolf A, Sheng-Yang GM, Paoletti M, Toller G, Caverzasi E, Luisa Mandelli M, Illán-Gala I, Kramer JH, Cobigo Y, Miller BL, Rosen HJ, Geschwind MD. PMID: 33949799; PMCID: PMC8164858.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    25. Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration. Neurology. 2021 05 04; 96(18):e2296-e2312. Rojas JC, Wang P, Staffaroni AM, Heller C, Cobigo Y, Wolf A, Goh SM, Ljubenkov PA, Heuer HW, Fong JC, Taylor JB, Veras E, Song L, Jeromin A, Hanlon D, Yu L, Khinikar A, Sivasankaran R, Kieloch A, Valentin MA, Karydas AM, Mitic LL, Pearlman R, Kornak J, Kramer JH, Miller BL, Kantarci K, Knopman DS, Graff-Radford N, Petrucelli L, Rademakers R, Irwin DJ, Grossman M, Ramos EM, Coppola G, Mendez MF, Bordelon Y, Dickerson BC, Ghoshal N, Huey ED, Mackenzie IR, Appleby BS, Domoto-Reilly K, Hsiung GR, Toga AW, Weintraub S, Kaufer DI, Kerwin D, Litvan I, Onyike CU, Pantelyat A, Roberson ED, Tartaglia MC, Foroud T, Chen W, Czerkowicz J, Graham DL, van Swieten JC, Borroni B, Sanchez-Valle R, Moreno F, Laforce R, Graff C, Synofzik M, Galimberti D, Rowe JB, Masellis M, Finger E, Vandenberghe R, de Mendonça A, Tagliavini F, Santana I, Ducharme S, Butler CR, Gerhard A, Levin J, Danek A, Otto M, Sorbi S, Cash DM, Convery RS, Bocchetta M, Foiani M, Greaves CV, Peakman G, Russell L, Swift I, Todd E, Rohrer JD, Boeve BF, Rosen HJ, Boxer AL, ALLFTD and GENFI consortia. PMID: 33827960; PMCID: PMC8166434.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCTClinical Trials
    26. Plasma Glial Fibrillary Acidic Protein Levels Differ Along the Spectra of Amyloid Burden and Clinical Disease Stage. J Alzheimers Dis. 2021; 80(1):471-474. Asken BM, Elahi FM, La Joie R, Strom A, Staffaroni AM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Karydas A, Wang P, Rojas JC, Boxer AL, Miller BL, Rabinovici GD, Kramer JH, Casaletto KB. PMID: 33612550.
      View in: PubMed   Mentions: 6     Fields:    
    27. Plasma Tau and Neurofilament Light in Frontotemporal Lobar Degeneration and Alzheimer Disease. Neurology. 2021 02 02; 96(5):e671-e683. Illán-Gala I, Lleo A, Karydas A, Staffaroni AM, Zetterberg H, Sivasankaran R, Grinberg LT, Spina S, Kramer JH, Ramos EM, Coppola G, La Joie R, Rabinovici GD, Perry DC, Gorno-Tempini ML, Seeley WW, Miller BL, Rosen HJ, Blennow K, Boxer AL, Rojas JC. PMID: 33199433; PMCID: PMC7884995.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    28. Four-Repeat Tauopathies: Current Management and Future Treatments. Neurotherapeutics. 2020 10; 17(4):1563-1581. VandeVrede L, Ljubenkov PA, Rojas JC, Welch AE, Boxer AL. PMID: 32676851; PMCID: PMC7851277.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    29. Open-Label Phase 1 Futility Studies of Salsalate and Young Plasma in Progressive Supranuclear Palsy. Mov Disord Clin Pract. 2020 May; 7(4):440-447. VandeVrede L, Dale ML, Fields S, Frank M, Hare E, Heuer HW, Keith K, Koestler M, Ljubenkov PA, McDermott D, Ohanesian N, Richards J, Rojas JC, Thijssen EH, Walsh C, Wang P, Wolf A, Quinn JF, Tsai R, Boxer AL. PMID: 32373661; PMCID: PMC7197321.
      View in: PubMed   Mentions: 23  
    30. Diagnostic value of plasma phosphorylated tau181 in Alzheimer's disease and frontotemporal lobar degeneration. Nat Med. 2020 03; 26(3):387-397. Thijssen EH, La Joie R, Wolf A, Strom A, Wang P, Iaccarino L, Bourakova V, Cobigo Y, Heuer H, Spina S, VandeVrede L, Chai X, Proctor NK, Airey DC, Shcherbinin S, Duggan Evans C, Sims JR, Zetterberg H, Blennow K, Karydas AM, Teunissen CE, Kramer JH, Grinberg LT, Seeley WW, Rosen H, Boeve BF, Miller BL, Rabinovici GD, Dage JL, Rojas JC, Boxer AL, Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL) investigators. PMID: 32123386; PMCID: PMC7101073.
      View in: PubMed   Mentions: 284     Fields:    Translation:HumansCells
    31. Reactions to Multiple Ascending Doses of the Microtubule Stabilizer TPI-287 in Patients With Alzheimer Disease, Progressive Supranuclear Palsy, and Corticobasal Syndrome: A Randomized Clinical Trial. JAMA Neurol. 2020 02 01; 77(2):215-224. Tsai RM, Miller Z, Koestler M, Rojas JC, Ljubenkov PA, Rosen HJ, Rabinovici GD, Fagan AM, Cobigo Y, Brown JA, Jung JI, Hare E, Geldmacher DS, Natelson-Love M, McKinley EC, Luong PN, Chuu EL, Powers R, Mumford P, Wolf A, Wang P, Shamloo M, Miller BL, Roberson ED, Boxer AL. PMID: 31710340; PMCID: PMC6865783.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    32. Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy. Mol Neurodegener. 2020 01 06; 15(1):2. Chen X, Li Y, Wang C, Tang Y, Mok SA, Tsai RM, Rojas JC, Karydas A, Miller BL, Boxer AL, Gestwicki JE, Arkin M, Cuervo AM, Gan L. PMID: 31906970; PMCID: PMC6945522.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    33. Plasma Glial Fibrillary Acidic Protein Levels Differ Along the Spectra of Amyloid Burden and Clinical Disease Stage. J Alzheimers Dis. 2020; 78(1):265-276. Asken BM, Elahi FM, La Joie R, Strom A, Staffaroni AM, Lindbergh CA, Apple AC, You M, Weiner-Light S, Brathaban N, Fernandes N, Karydas A, Wang P, Rojas JC, Boxer AL, Miller BL, Rabinovici GD, Kramer JH, Casaletto KB. PMID: 32986672; PMCID: PMC7727314.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    34. Prospective longitudinal atrophy in Alzheimer's disease correlates with the intensity and topography of baseline tau-PET. Sci Transl Med. 2020 01 01; 12(524). La Joie R, Visani AV, Baker SL, Brown JA, Bourakova V, Cha J, Chaudhary K, Edwards L, Iaccarino L, Janabi M, Lesman-Segev OH, Miller ZA, Perry DC, O'Neil JP, Pham J, Rojas JC, Rosen HJ, Seeley WW, Tsai RM, Miller BL, Jagust WJ, Rabinovici GD. PMID: 31894103; PMCID: PMC7035952.
      View in: PubMed   Mentions: 194     Fields:    Translation:Humans
    35. 4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration. Acta Neuropathol. 2020 01; 139(1):63-77. Saijo E, Metrick MA, Koga S, Parchi P, Litvan I, Spina S, Boxer A, Rojas JC, Galasko D, Kraus A, Rossi M, Newell K, Zanusso G, Grinberg LT, Seeley WW, Ghetti B, Dickson DW, Caughey B. PMID: 31616982; PMCID: PMC7192393.
      View in: PubMed   Mentions: 63     Fields:    Translation:Humans
    36. Peripheral Innate Immune Activation Correlates With Disease Severity in GRN Haploinsufficiency. Front Neurol. 2019; 10:1004. Ljubenkov PA, Miller Z, Mumford P, Zhang J, Allen IE, Mitic L, Staffaroni A, Heuer H, Rojas JC, Cobigo Y, Karydas A, Pearlman R, Miller B, Kramer JH, McGrath MS, Rosen HJ, Boxer AL. PMID: 31620075; PMCID: PMC6759464.
      View in: PubMed   Mentions: 5  
    37. Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis. JAMA Neurol. 2019 Sep 01; 76(9):1035-1048. Bridel C, van Wieringen WN, Zetterberg H, Tijms BM, Teunissen CE, and the NFL Group, Alvarez-Cermeño JC, Andreasson U, Axelsson M, Bäckström DC, Bartos A, Bjerke M, Blennow K, Boxer A, Brundin L, Burman J, Christensen T, Fialová L, Forsgren L, Frederiksen JL, Gisslén M, Gray E, Gunnarsson M, Hall S, Hansson O, Herbert MK, Jakobsson J, Jessen-Krut J, Janelidze S, Johannsson G, Jonsson M, Kappos L, Khademi M, Khalil M, Kuhle J, Landén M, Leinonen V, Logroscino G, Lu CH, Lycke J, Magdalinou NK, Malaspina A, Mattsson N, Meeter LH, Mehta SR, Modvig S, Olsson T, Paterson RW, Pérez-Santiago J, Piehl F, Pijnenburg YAL, Pyykkö OT, Ragnarsson O, Rojas JC, Romme Christensen J, Sandberg L, Scherling CS, Schott JM, Sellebjerg FT, Simone IL, Skillbäck T, Stilund M, Sundström P, Svenningsson A, Tortelli R, Tortorella C, Trentini A, Troiano M, Turner MR, van Swieten JC, Vågberg M, Verbeek MM, Villar LM, Visser PJ, Wallin A, Weiss A, Wikkelsø C, Wild EJ. PMID: 31206160; PMCID: PMC6580449.
      View in: PubMed   Mentions: 270     Fields:    
    38. Association of Blood and Cerebrospinal Fluid Tau Level and Other Biomarkers With Survival Time in Sporadic Creutzfeldt-Jakob Disease. JAMA Neurol. 2019 Aug 01; 76(8):969-977. Staffaroni AM, Kramer AO, Casey M, Kang H, Rojas JC, Orrú CD, Caughey B, Allen IE, Kramer JH, Rosen HJ, Blennow K, Zetterberg H, Geschwind MD. PMID: 31058916; PMCID: PMC6503575.
      View in: PubMed   Mentions: 42     Fields:    
    39. Clinical value of cerebrospinal fluid neurofilament light chain in semantic dementia. J Neurol Neurosurg Psychiatry. 2019 09; 90(9):997-1004. Meeter LHH, Steketee RME, Salkovic D, Vos ME, Grossman M, McMillan CT, Irwin DJ, Boxer AL, Rojas JC, Olney NT, Karydas A, Miller BL, Pijnenburg YAL, Barkhof F, Sánchez-Valle R, Lladó A, Borrego-Ecija S, Diehl-Schmid J, Grimmer T, Goldhardt O, Santillo AF, Hansson O, Vestberg S, Borroni B, Padovani A, Galimberti D, Scarpini E, Rohrer JD, Woollacott IOC, Synofzik M, Wilke C, de Mendonca A, Vandenberghe R, Benussi L, Ghidoni R, Binetti G, Niessen WJ, Papma JM, Seelaar H, Jiskoot LC, de Jong FJ, Donker Kaat L, Del Campo M, Teunissen CE, Bron EE, Van den Berg E, Van Swieten JC. PMID: 31123142; PMCID: PMC6820157.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    40. Cerebrospinal fluid biomarkers predict frontotemporal dementia trajectory. Ann Clin Transl Neurol. 2018 Oct; 5(10):1250-1263. Ljubenkov PA, Staffaroni AM, Rojas JC, Allen IE, Wang P, Heuer H, Karydas A, Kornak J, Cobigo Y, Seeley WW, Grinberg LT, Spina S, Fagan AM, Jerome G, Knopman D, Boeve BF, Dickerson BC, Kramer J, Miller B, Boxer AL, Rosen HJ. PMID: 30349860; PMCID: PMC6186942.
      View in: PubMed   Mentions: 25     Fields:    
    41. A comparison of biofluid cytokine markers across platform technologies: Correspondence or divergence? Cytokine. 2018 11; 111:481-489. Casaletto KB, Elahi FM, Fitch R, Walters S, Fox E, Staffaroni AM, Bettcher BM, Zetterberg H, Karydas A, Rojas JC, Boxer AL, Kramer JH. PMID: 29908923; PMCID: PMC6289877.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    42. Poly(GP), neurofilament and grey matter deficits in C9orf72 expansion carriers. Ann Clin Transl Neurol. 2018 May; 5(5):583-597. Meeter LHH, Gendron TF, Sias AC, Jiskoot LC, Russo SP, Donker Kaat L, Papma JM, Panman JL, van der Ende EL, Dopper EG, Franzen S, Graff C, Boxer AL, Rosen HJ, Sanchez-Valle R, Galimberti D, Pijnenburg YAL, Benussi L, Ghidoni R, Borroni B, Laforce R, Del Campo M, Teunissen CE, van Minkelen R, Rojas JC, Coppola G, Geschwind DH, Rademakers R, Karydas AM, Öijerstedt L, Scarpini E, Binetti G, Padovani A, Cash DM, Dick KM, Bocchetta M, Miller BL, Rohrer JD, Petrucelli L, van Swieten JC, Lee SE. PMID: 29761121; PMCID: PMC5945959.
      View in: PubMed   Mentions: 28     Fields:    
    43. Multiproteinopathy, neurodegeneration and old age: a case study. Neurocase. 2018 02; 24(1):1-6. Rojas JC, Stephens ML, Rabinovici GD, Kramer JH, Miller BL, Seeley WW. PMID: 29307276; PMCID: PMC5877460.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    44. CSF neurofilament light chain and phosphorylated tau 181 predict disease progression in PSP. Neurology. 2018 01 23; 90(4):e273-e281. Rojas JC, Bang J, Lobach IV, Tsai RM, Rabinovici GD, Miller BL, Boxer AL, AL-108-231 Investigators. PMID: 29282336; PMCID: PMC5798651.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCellsCTClinical Trials
    45. ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy. Nature. 2017 09 28; 549(7673):523-527. Shi Y, Yamada K, Liddelow SA, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC, Gallardo G, Wang K, Roh J, Robinson G, Finn MB, Jiang H, Sullivan PM, Baufeld C, Wood MW, Sutphen C, McCue L, Xiong C, Del-Aguila JL, Morris JC, Cruchaga C, Alzheimer’s Disease Neuroimaging Initiative, Fagan AM, Miller BL, Boxer AL, Seeley WW, Butovsky O, Barres BA, Paul SM, Holtzman DM. PMID: 28959956; PMCID: PMC5641217.
      View in: PubMed   Mentions: 519     Fields:    Translation:HumansAnimalsCells
    46. Genetic Prion Disease Caused by PRNP Q160X Mutation Presenting with an Orbitofrontal Syndrome, Cyclic Diarrhea, and Peripheral Neuropathy. J Alzheimers Dis. 2017; 55(1):249-258. Fong JC, Rojas JC, Bang J, Legati A, Rankin KP, Forner S, Miller ZA, Karydas AM, Coppola G, Grouse CK, Ralph J, Miller BL, Geschwind MD. PMID: 27716661; PMCID: PMC5149415.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    47. Distinct Lysosomal Network Protein Profiles in Parkinsonian Syndrome Cerebrospinal Fluid. J Parkinsons Dis. 2016 04 02; 6(2):307-15. Boman A, Svensson S, Boxer A, Rojas JC, Seeley WW, Karydas A, Miller B, Kågedal K, Svenningsson P. PMID: 27061067; PMCID: PMC4927933.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    48. Plasma neurofilament light chain predicts progression in progressive supranuclear palsy. Ann Clin Transl Neurol. 2016 03; 3(3):216-25. Rojas JC, Karydas A, Bang J, Tsai RM, Blennow K, Liman V, Kramer JH, Rosen H, Miller BL, Zetterberg H, Boxer AL. PMID: 27042681; PMCID: PMC4774256.
      View in: PubMed   Mentions: 88     Fields:    
    49. Neurodegenerative disease in 2015: Targeting tauopathies for therapeutic translation. Nat Rev Neurol. 2016 Feb; 12(2):74-6. Rojas JC, Boxer AL. PMID: 26794651; PMCID: PMC5221610.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    50. Factors contributing to delay in diagnosis of Guillain-Barré syndrome and impact on clinical outcome. Muscle Nerve. 2016 Mar; 53(3):384-7. Dubey D, Kapotic M, Freeman M, Sawhney A, Rojas JC, Warnack W, Vernino S. PMID: 26185107.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    51. Neuritis ossificans. Response. J Neurosurg. 2014 Nov; 121(5):1288-9. Kemper CM, Rojas JC, Bauserman S. PMID: 25525654.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    52. Mitochondrial respiration as a target for neuroprotection and cognitive enhancement. Biochem Pharmacol. 2014 Apr 15; 88(4):584-93. Gonzalez-Lima F, Barksdale BR, Rojas JC. PMID: 24316434.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    53. Clinical Reasoning: a woman with recurrent aphasia and visual field defects. Neurology. 2013 Nov 05; 81(19):e141-4. Nourbakhsh B, Rojas JC, Banerjee C, Novakovic RL, Warnack W. PMID: 24190002.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    54. Neurological and psychological applications of transcranial lasers and LEDs. Biochem Pharmacol. 2013 Aug 15; 86(4):447-57. Rojas JC, Gonzalez-Lima F. PMID: 23806754.
      View in: PubMed   Mentions: 63     Fields:    Translation:Humans
    55. Pearls and oy-sters: acute ischemic stroke caused by atypical thrombotic thrombocytopenic purpura. Neurology. 2013 May 28; 80(22):e235-8. Rojas JC, Banerjee C, Siddiqui F, Nourbakhsh B, Powell CM. PMID: 23713092; PMCID: PMC3716404.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    56. Low-level light therapy improves cortical metabolic capacity and memory retention. J Alzheimers Dis. 2012; 32(3):741-52. Rojas JC, Bruchey AK, Gonzalez-Lima F. PMID: 22850314.
      View in: PubMed   Mentions: 54     Fields:    Translation:Animals
    57. Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue. Prog Neurobiol. 2012 Jan; 96(1):32-45. Rojas JC, Bruchey AK, Gonzalez-Lima F. PMID: 22067440; PMCID: PMC3265679.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    58. Low-level light therapy of the eye and brain. Eye Brain. 2011; 3:49-67. Rojas JC, Gonzalez-Lima F. PMID: 28539775; PMCID: PMC5436183.
      View in: PubMed   Mentions: 80  
    59. Beneficial network effects of methylene blue in an amnestic model. Neuroimage. 2011 Feb 14; 54(4):2623-34. Riha PD, Rojas JC, Gonzalez-Lima F. PMID: 21087672; PMCID: PMC3026638.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    60. [Genetic thrombophilia and markers of endothelial activation in patients with preeclampsia]. Ginecol Obstet Mex. 2010 Aug; 78(8):401-9. Rojas JC, Luna M, Rangel-Nava H, Baños D, Collados MT. PMID: 20939248.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    61. Neuritis ossificans of a cranial nerve. J Neurosurg. 2010 Nov; 113(5):1112-4. Kemper CM, Rojas JC, Bauserman S. PMID: 20509727.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    62. In vivo low-level light therapy increases cytochrome oxidase in skeletal muscle. Photochem Photobiol. 2010 May-Jun; 86(3):673-80. Hayworth CR, Rojas JC, Padilla E, Holmes GM, Sheridan EC, Gonzalez-Lima F. PMID: 20408982.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    63. Mitochondrial optic neuropathy: In vivo model of neurodegeneration and neuroprotective strategies. Eye Brain. 2010; 2:21-37. Rojas JC, Gonzalez-Lima F. PMID: 28539759; PMCID: PMC5436181.
      View in: PubMed   Mentions: 8  
    64. Striatal neuroprotection with methylene blue. Neuroscience. 2009 Oct 20; 163(3):877-89. Rojas JC, Simola N, Kermath BA, Kane JR, Schallert T, Gonzalez-Lima F. PMID: 19596056; PMCID: PMC2765788.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    65. Methylene blue provides behavioral and metabolic neuroprotection against optic neuropathy. Neurotox Res. 2009 Apr; 15(3):260-73. Rojas JC, John JM, Lee J, Gonzalez-Lima F. PMID: 19384599.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    66. Neuroprotective effects of near-infrared light in an in vivo model of mitochondrial optic neuropathy. J Neurosci. 2008 Dec 10; 28(50):13511-21. Rojas JC, Lee J, John JM, Gonzalez-Lima F. PMID: 19074024; PMCID: PMC2637249.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    67. Neuroprotective effects of memantine in a mouse model of retinal degeneration induced by rotenone. Brain Res. 2008 Jun 18; 1215:208-17. Rojas JC, Saavedra JA, Gonzalez-Lima F. PMID: 18486118; PMCID: PMC2491399.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    68. Animal model of posterior cingulate cortex hypometabolism implicated in amnestic MCI and AD. Neurobiol Learn Mem. 2008 Jul; 90(1):112-24. Riha PD, Rojas JC, Colorado RA, Gonzalez-Lima F. PMID: 18316212; PMCID: PMC2494556.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    69. Transgenic mice expressing cyan fluorescent protein as a reporter strain to detect the effects of rotenone toxicity on retinal ganglion cells. J Toxicol Environ Health A. 2008; 71(24):1582-92. Hayworth CR, Rojas JC, Gonzalez-Lima F. PMID: 18850458.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    70. Methylene blue prevents neurodegeneration caused by rotenone in the retina. Neurotox Res. 2006 Jan; 9(1):47-57. Zhang X, Rojas JC, Gonzalez-Lima F. PMID: 16464752.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    71. Pharmacogenetics of oral anticoagulants. Blood Coagul Fibrinolysis. 2005 Sep; 16(6):389-98. Rojas JC, Aguilar B, Rodríguez-Maldonado E, Collados MT. PMID: 16093729.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    72. Induction of apoptosis and effect on CD20+ using rituximab on autologous peripheral blood stem cell harvests from patients with B cell lymphomas. Stem Cells Dev. 2004 Apr; 13(2):193-6. Borbolla-Escoboza JR, Leon MI, Collados MT, Baez E, Baltasar S, Hernández R, Rojas JC. PMID: 15186735.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
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