Nicolas Prionas, MD, PhD

Title(s)Assistant Professor, Radiation Oncology
SchoolSchool of Medicine
Address1600 Divisadero, #H1029
San Francisco CA 94115
PronounsHe/Him/His
ORCID ORCID Icon0000-0001-5067-7077 Additional info
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    Collapse Biography 
    Collapse education and training
    University of California, San Francisco, San Francisco, CA2023UCSF Health Lean Champion
    University of California, San Francisco, San Francisco, CA2019Diversity, Equity, and Inclusion Champion
    Stanford University, Stanford, CAResidency2019Radiation Oncology
    Santa Clara Valley Medical Center, Santa Clara, CAInternship2015Medicine (Transitional)
    University of California, Davis, Sacramento, CAPhD2012Biomedical Engineering
    University of California, Davis, Sacramento, CAMD2014Medicine
    Stanford University, Stanford, CAMS2006Biomechanical Engineering
    Stanford University, Stanford, CABS2005Biomedical Computation

    Collapse Overview 
    Collapse overview
    Dr. Nicolas Prionas, M.D. Ph.D., is a radiation oncologist with clinical expertise and interest in the detection, diagnosis, and management of breast cancer. As a native of the San Francisco Bay Area, he is passionate about bringing UCSF care into the community across the entire region. He has expertise in specialized procedures including intensity modulated radiotherapy (IMRT), stereotactic ablative/body radiotherapy (SABR/SBRT), stereotactic radiosurgery (SRS), image-guided radiotherapy (IGRT), and intra-operative radiotherapy (IORT).

    Dr. Prionas received a B.S. in Biomedical Computation and a M.S. in Biomechanical Engineering from Stanford University. He completed joint MD/PhD training in Biomedical Engineering at the University of California, Davis School of Medicine where his research specialized in quantitative imaging and radiotherapy using a novel dedicated breast computed tomography platform. Prior to arriving at UCSF, he completed Radiation Oncology Residency training at Stanford University where he was awarded the Malcolm A. Bagshaw Award for leadership and outstanding scientific achievement. Dr. Prionas is the Director of Quality and his research focuses on technologies that increase access to equitable care.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The climate and health impact of U.S. radiation therapy: estimating greenhouse gas emissions, DALYs, and potential of hypofractionation. Radiother Oncol. 2025 Sep 20; 111161. Lichter KE, Asaro A, Qureshi MM, Truong MT, Parekh A, Witztum A, Anand C, Silva GS, Royce T, Zaorsky NG, Grover S, Abdel-Wahab M, Thiel C, Eckelman MJ, Prionas N, Yom SS, Mohamad O. PMID: 40983187.
      View in: PubMed   Mentions:
    2. Impact of Time to Surgery Post Neoadjuvant Chemotherapy on Breast Cancer Outcomes: A Retrospective Study of Patients Enrolled in the I-SPY 2 Clinical Trial. Ann Surg Oncol. 2025 Aug 23. Van Hassel J, Dimitroff K, Yau C, Mukhtar R, Boughey JC, Ladores V, Howard-McNatt MM, Jaskowiak N, Perlmutter J, DeMichele A, Yee D, Hylton N, Symmans WF, Veer LV, Rugo H, Esserman LJ, Shatsky R, Isaacs C, Kuerer H, Wallace AM, Prionas N, Tseng J, Reyna CR, Taunk N, Kesmodel S, Lee MC, Fox J, Piltin MA, Tchou J, Arciero CA, Postlewait LM, Sauder C, Rao R. PMID: 40849380.
      View in: PubMed   Mentions:    Fields:    
    3. Impact of Neoadjuvant Chemotherapy on Surgical Outcomes and Conversion to Node-Negativity in Invasive Lobular Breast Cancer: Analysis of Molecularly High-Risk Tumors by Histologic Subtype on the I-SPY2 Clinical Trial. Ann Surg Oncol. 2025 Jul 24. Mukhtar RA, Dimitroff K, Yau C, Chien AJ, Connolly EP, Howard-McNatt M, Rao R, Ladores V, Golshan M, Sauder CA, Ahmed K, Lancaster R, Fox J, Gutnik L, Lee MC, Tchou J, Prionas N, Arciero CA, Reyna C, Kuerer H, Switalla K, Taunk N, Tuttle TM, Moran MS, Postlewait LM, Perlmutter J, DeMichele A, Yee D, Hylton N, Symmans WF, Rugo HS, Shatsky R, Isaacs C, Esserman LJ, Van't Veer L, Boughey JC. PMID: 40705266.
      View in: PubMed   Mentions:    Fields:    
    4. Disparities in the Surgical Management of the Axilla by Self-Identified Race in the Multicenter Neoadjuvant I-SPY2 Trial. Ann Surg Oncol. 2025 Jul 23. Kaur M, Dimitroff K, Boughey JC, Esserman LJ, Yau C, Tchou J, Quirarte A, Lee MC, Howard-McNatt MM, Switalla K, Kuerer H, Sauder C, Postlewait LM, Arciero C, Rao R, Wallace A, Reyna C, Ahmed K, Gutnik L, Taunk N, Perlmutter J, DeMichele A, Yee D, Hylton NM, Symmans WF, Rugo HS, Shatsky RA, Isaacs C, Rudra S, Pohlmann P, Ewing C, Wong J, Alvarado M, Jaskowiak N, Prionas N, Golshan M, Piltin MA, Olopade OI, Mukhtar RA. PMID: 40699532.
      View in: PubMed   Mentions:    Fields:    
    5. The NorCal brachytherapy waste audit: A simple, validated, toolkit for clinician led waste reduction. Brachytherapy. 2025 Mar 01. Baniel CC, Lichter KE, Frick MA, Wu J, Oladipo E, Wu YF, SwamyS A, Hsu IC, Prionas N, Blomain ES, Kidd EA, Buyyounouski MK, Rosenbluth G, Mohamad O, Bagshaw HP. PMID: 40024828.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    6. Exploring the Social Media Discussion of Breast Cancer Treatment Choices: Quantitative Natural Language Processing Study. JMIR Cancer. 2025 Jan 28; 11:e52886. Spiegel DY, Friesner ID, Zhang W, Zack T, Yan G, Willcox J, Prionas N, Singer L, Park C, Hong JC. PMID: 39881478; PMCID: PMC11793830.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Management of Concurrent Malignant Phyllodes Tumor and Invasive Breast Carcinoma. Adv Radiat Oncol. 2024 May; 9(5):101448. Chen JJ, Zhu I, Patel A, Krings G, Chen YY, Yuen F, Mukhtar RA, Melisko M, Singer L, Park CC, Prionas ND. PMID: 38550370; PMCID: PMC10965428.
      View in: PubMed   Mentions: 2  
    8. A Couch Mounted Smartphone-based Motion Monitoring System for Radiation Therapy. Pract Radiat Oncol. 2024 Mar-Apr; 14(2):161-170. Capaldi DPI, Axente M, Yu AS, Prionas ND, Hirata E, Nano TF. PMID: 38052299.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Modifiable Postmastectomy Radiation Therapy Factors and Impact on Implant-Based Breast Reconstruction Outcomes. Plast Reconstr Surg. 2024 May 01; 153(5):1000-1009. Barnes LL, Chew J, Lem M, Park C, Yang JC, Prionas N, Piper M. PMID: 37335545.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    10. Early-stage Breast Cancer: Tailored External Beam Fractionation Approaches for Treatment of the Whole or Partial Breast. Semin Radiat Oncol. 2022 07; 32(3):245-253. Prionas ND, Stephens SJ, Blitzblau RC. PMID: 35688523.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Contralateral Disease Begets Contralateral Treatment. Int J Radiat Oncol Biol Phys. 2022 07 01; 113(3):490. Prionas ND, Park CC. PMID: 35777389.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Positive margins after mastectomy in patients with invasive lobular carcinoma of the breast: Incidence and management strategies. Am J Surg. 2022 04; 223(4):699-704. Hewitt KC, Miller P, Piper M, Prionas N, Son JD, Alvarado M, Esserman LJ, Wong JM, Ewing C, Mukhtar RA. PMID: 34148670.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    13. A pilot, randomized controlled trial of telementorship: A useful tool during social distancing. J Clin Transl Res. 2021 Feb 25; 7(1):66-71. Prionas ND, Kung TH, Dohn A, Piro N, von Eyben R, Katznelson L, Caruso TJ. PMID: 34104809; PMCID: PMC8177021.
      View in: PubMed   Mentions: 4  
    14. Dose-response with stereotactic body radiotherapy for prostate cancer: A multi-institutional analysis of prostate-specific antigen kinetics and biochemical control. Radiother Oncol. 2021 01; 154:207-213. Levin-Epstein RG, Jiang NY, Wang X, Upadhyaya SK, Collins SP, Suy S, Aghdam N, Mantz C, Katz AJ, Miszczyk L, Napieralska A, Namysl-Kaletka A, Prionas N, Bagshaw H, Buyyounouski MK, Cao M, Agazaryan N, Dang A, Yuan Y, Kupelian PA, Zaorsky NG, Spratt DE, Mohamad O, Feng FY, Mahal BA, Boutros PC, Kishan AU, Juarez J, Shabsovich D, Jiang T, Kahlon S, Patel A, Patel J, Nickols NG, Steinberg ML, Fuller DB, Kishan AU. PMID: 33035622; PMCID: PMC7956167.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    15. Telemedicine in Radiation Oncology: Is It Here to Stay? Impacts on Patient Care and Resident Education. Int J Radiat Oncol Biol Phys. 2020 Oct 01; 108(2):416-420. Gutkin PM, Prionas ND, Minneci MO, Allen E, Balazy KE, Rahimy E, Chang DT, Horst KC. PMID: 32890524; PMCID: PMC7462793.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansPHPublic Health
    16. Intensity modulated Ir-192 brachytherapy using high-Z 3D printed applicators. Phys Med Biol. 2020 07 31; 65(15):155018. Skinner LB, Niedermayr T, Prionas N, Perl J, Fahimian B, Kidd EA. PMID: 32521512.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    17. Prostate-specific antigen kinetics and biochemical control following stereotactic body radiation therapy, high dose rate brachytherapy, and low dose rate brachytherapy: A multi-institutional analysis of 3502 patients. Radiother Oncol. 2020 10; 151:26-32. Levin-Epstein R, Cook RR, Wong JK, Stock RG, Jeffrey Demanes D, Collins SP, Aghdam N, Suy S, Mantz C, Katz AJ, Nickols NG, Miszczyk L, Napieralska A, Namysl-Kaletka A, Prionas ND, Bagshaw H, Buyyounouski MK, Cao M, Mahal BA, Shabsovich D, Dang A, Yuan Y, Rettig MB, Chang AJ, Jackson WC, Spratt DE, Lehrer EJ, Zaorsky NG, Kupelian PA, Steinberg ML, Horwitz EM, Jiang NY, Kishan AU. PMID: 32663537.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    18. Predicting Survival for Patients With Metastatic Disease. Int J Radiat Oncol Biol Phys. 2020 01 01; 106(1):52-60. Benson KRK, Aggarwal S, Carter JN, von Eyben R, Pradhan P, Prionas ND, Bui JL, Soltys SG, Hancock S, Gensheimer MF, Koong AC, Chang DT. PMID: 31682969.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    19. Multi-Institutional Analysis of Prostate-Specific Antigen Kinetics After Stereotactic Body Radiation Therapy. Int J Radiat Oncol Biol Phys. 2019 11 01; 105(3):628-636. Jiang NY, Dang AT, Yuan Y, Chu FI, Shabsovich D, King CR, Collins SP, Aghdam N, Suy S, Mantz CA, Miszczyk L, Napieralska A, Namysl-Kaletka A, Bagshaw H, Prionas N, Buyyounouski MK, Jackson WC, Spratt DE, Nickols NG, Steinberg ML, Kupelian PA, Kishan AU. PMID: 31276777.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    20. Long-term Outcomes of Stereotactic Body Radiotherapy for Low-Risk and Intermediate-Risk Prostate Cancer. JAMA Netw Open. 2019 02 01; 2(2):e188006. Kishan AU, Dang A, Katz AJ, Mantz CA, Collins SP, Aghdam N, Chu FI, Kaplan ID, Appelbaum L, Fuller DB, Meier RM, Loblaw DA, Cheung P, Pham HT, Shaverdian N, Jiang N, Yuan Y, Bagshaw H, Prionas N, Buyyounouski MK, Spratt DE, Linson PW, Hong RL, Nickols NG, Steinberg ML, Kupelian PA, King CR. PMID: 30735235; PMCID: PMC6484596.
      View in: PubMed   Mentions: 142     Fields:    Translation:Humans
    21. Increases in Serial Pretreatment 18F-FDG PET-CT Metrics Predict Survival in Early Stage Non-Small Cell Lung Cancer Treated With Stereotactic Ablative Radiation Therapy. Adv Radiat Oncol. 2019 Apr-Jun; 4(2):429-437. Prionas ND, von Eyben R, Yi E, Aggarwal S, Shaffer J, Bazan J, Eastham D, Maxim PG, Graves EE, Diehn M, Gensheimer MF, Loo BW. PMID: 31011689; PMCID: PMC6460103.
      View in: PubMed   Mentions: 1  
    22. 18F-EF5 PET-based Imageable Hypoxia Predicts Local Recurrence in Tumors Treated With Highly Conformal Radiation Therapy. Int J Radiat Oncol Biol Phys. 2018 11 15; 102(4):1183-1192. Qian Y, Von Eyben R, Liu Y, Chin FT, Miao Z, Apte S, Carter JN, Binkley MS, Pollom EL, Harris JP, Prionas ND, Kissel M, Simmons A, Diehn M, Shultz DB, Brown JM, Maxim PG, Koong AC, Graves EE, Loo BW. PMID: 29859786.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    23. SBRT and HDR brachytherapy produce lower PSA nadirs and different PSA decay patterns than conventionally fractionated IMRT in patients with low- or intermediate-risk prostate cancer. Pract Radiat Oncol. 2016 Jul-Aug; 6(4):268-275. Kishan AU, Wang PC, Upadhyaya SK, Hauswald H, Demanes DJ, Nickols NG, Kamrava M, Sadeghi A, Kupelian PA, Steinberg ML, Prionas ND, Buyyounouski MK, King CR. PMID: 26850649.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    24. Differentiation of ductal carcinoma in-situ from benign micro-calcifications by dedicated breast computed tomography. Eur J Radiol. 2016 Jan; 85(1):297-303. Aminololama-Shakeri S, Abbey CK, Gazi P, Prionas ND, Nosratieh A, Li CS, Boone JM, Lindfors KK. PMID: 26520874; PMCID: PMC4698333.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    25. Development of a patient-specific two-compartment anthropomorphic breast phantom. Phys Med Biol. 2012 Jul 07; 57(13):4293-307. Prionas ND, Burkett GW, McKenney SE, Chen L, Stern RL, Boone JM. PMID: 22705748; PMCID: PMC3404613.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    26. Kilovoltage rotational external beam radiotherapy on a breast computed tomography platform: a feasibility study. Int J Radiat Oncol Biol Phys. 2012 Oct 01; 84(2):533-9. Prionas ND, McKenney SE, Stern RL, Boone JM. PMID: 22436786; PMCID: PMC3397279.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    27. Persistent CT nephrograms following cardiac catheterisation and intervention: initial observations. Insights Imaging. 2012 Feb; 3(1):49-60. Katzberg RW, Monsky WL, Prionas ND, Sidhar V, Southard J, Carlson J, Boone JM, Lin TC, Li CS. PMID: 22695998; PMCID: PMC3292644.
      View in: PubMed   Mentions: 3  
    28. The characterization of breast anatomical metrics using dedicated breast CT. Med Phys. 2011 Apr; 38(4):2180-91. Huang SY, Boone JM, Yang K, Packard NJ, McKenney SE, Prionas ND, Lindfors KK, Yaffe MJ. PMID: 21626952; PMCID: PMC3081868.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    29. Experimentally determined spectral optimization for dedicated breast computed tomography. Med Phys. 2011 Feb; 38(2):646-55. Prionas ND, Huang SY, Boone JM. PMID: 21452702; PMCID: PMC3033876.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    30. Contrast-enhanced dedicated breast CT: initial clinical experience. Radiology. 2010 Sep; 256(3):714-23. Prionas ND, Lindfors KK, Ray S, Huang SY, Beckett LA, Monsky WL, Boone JM. PMID: 20720067; PMCID: PMC2923727.
      View in: PubMed   Mentions: 96     Fields:    Translation:Humans
    31. Longitudinal volume analysis from computed tomography: Reproducibility using adrenal glands as surrogate tumors. J Med Phys. 2010 Jul; 35(3):174-80. Prionas ND, Gillen MA, Boone JM. PMID: 20927226; PMCID: PMC2936188.
      View in: PubMed   Mentions: 2  
    32. Volume assessment accuracy in computed tomography: a phantom study. J Appl Clin Med Phys. 2010 Apr 16; 11(2):3037. Prionas ND, Ray S, Boone JM. PMID: 20592693; PMCID: PMC3051348.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
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