Michael Alvarado, MD

Title(s)Professor, Surgery
SchoolSchool of Medicine
Address550 16th. Street, #6352
San Francisco CA 94158
Phone415-353-7908
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    DarmouthM.D.1998School of Medicine

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    Dr. Michael Alvarado is a cancer surgeon who cares for patients with breast cancer and melanoma at the UCSF Helen Diller Family Comprehensive Cancer Center at Mount Zion.

    In his research, Alvarado conducts trials of radiation therapy for breast cancer. He also studies blood-based and molecular markers with the goal of improving breast cancer screening.

    Alvarado earned a master's degree in chemistry at the University of Arizona and a medical degree at Dartmouth College’s Geisel School of Medicine. After completing a residency at Dartmouth-Hitchcock Medical Center, he completed a surgical oncology fellowship at the H. Lee Moffitt Cancer Center and Research Institute at the University of South Florida.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Predictors of Early Versus Late Recurrence in Invasive Lobular Carcinoma of the Breast: Impact of Local and Systemic Therapy. Ann Surg Oncol. 2023 Oct; 30(10):5999-6006. Rothschild HT, Clelland EN, Mujir F, Record H, Wong J, Esserman LJ, Alvarado M, Ewing C, Mukhtar RA. PMID: 37464134; PMCID: PMC10495501.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Changes in Surgical Management of the Axilla Over 11 Years - Report on More Than 1500 Breast Cancer Patients Treated with Neoadjuvant Chemotherapy on the Prospective I-SPY2 Trial. Ann Surg Oncol. 2023 Oct; 30(11):6401-6410. Boughey JC, Yu H, Dugan CL, Piltin MA, Postlewait L, Son JD, Edmiston KK, Godellas CV, Lee MC, Carr MJ, Tonneson JE, Crown A, Lancaster RB, Woriax HE, Ewing CA, Chau HS, Patterson AK, Wong JM, Alvarado MD, Yang RL, Chan TW, Sheade JB, Ahrendt GM, Larson KE, Switalla K, Tuttle TM, Tchou JC, Rao R, Tamirisa N, Singh P, Gould RE, Terando A, Sauder C, Hewitt K, Chiba A, Esserman LJ, Mukhtar RA. PMID: 37380911.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    3. Breast Conservation Surgery and Mastectomy Have Similar Locoregional Recurrence After Neoadjuvant Chemotherapy: Results From 1462 Patients on the Prospective, Randomized I-SPY2 Trial. Ann Surg. 2023 09 01; 278(3):320-327. Mukhtar RA, Chau H, Woriax H, Piltin M, Ahrendt G, Tchou J, Yu H, Ding Q, Dugan CL, Sheade J, Crown A, Carr M, Wong J, Son J, Yang R, Chan T, Terando A, Alvarado M, Ewing C, Tonneson J, Tamirisa N, Gould R, Singh P, Godellas C, Larson K, Chiba A, Rao R, Sauder C, Postlewait L, Lee MC, Symmans WF, Esserman LJ, Boughey JC, ISPY-2 Locoregional Working Group. PMID: 37325931.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    4. Expanding Candidacy for Nipple-sparing Mastectomy in Women with Large or Ptotic Breasts: Staged Reconstruction Outcomes. Plast Reconstr Surg Glob Open. 2023 Jan; 11(1):e4767. Barnes LL, Foster R, Mukhtar RA, Esserman LJ, Ewing C, Alvarado M, Wong J, Piper M. PMID: 36776594; PMCID: PMC9911193.
      View in: PubMed   Mentions:
    5. In Reply to Ward et al. Int J Radiat Oncol Biol Phys. 2023 Jan 01; 115(1):256-259. Leung S. PMID: 36526392.
      View in: PubMed   Mentions:    Fields:    
    6. In Regard to Hammer et al. Int J Radiat Oncol Biol Phys. 2023 Jan 01; 115(1):253-254. Onal C, Sezen D, Oymak E, Bölükbasi Y, Spratt DE, Ward MC, Fasola CE, White RL, Bentzen SM, Khan AJ, Vicini F, Shah C, Vaidya JS, Bulsara M, Wenz F, Sperk E, Massarut S, Alvarado M, Williams NR, Brew-Graves C, Bernstein M, Holmes D, Vinante L, Pigorsch S, Lundgren S, Uhl V, Joseph D, Tobias JS. PMID: 36526389.
      View in: PubMed   Mentions:    Fields:    
    7. The TARGIT-A Randomized Trial: TARGIT-IORT Versus Whole Breast Radiation Therapy: Long-Term Local Control and Survival. Int J Radiat Oncol Biol Phys. 2023 01 01; 115(1):77-82. Vaidya JS, Bulsara M, Wenz F, Sperk E, Massarut S, Alvarado M, Williams NR, Brew-Graves C, Bernstein M, Holmes D, Vinante L, Pigorsch S, Lundgren S, Uhl V, Joseph D, Tobias JS, TARGIT-A authors. PMID: 35998867.
      View in: PubMed   Mentions:    Fields:    
    8. Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2+ breast cancer in the adaptively randomized I-SPY2 trial. Nat Commun. 2021 11 05; 12(1):6428. Clark AS, Yau C, Wolf DM, Petricoin EF, van 't Veer LJ, Yee D, Moulder SL, Wallace AM, Chien AJ, Isaacs C, Boughey JC, Albain KS, Kemmer K, Haley BB, Han HS, Forero-Torres A, Elias A, Lang JE, Ellis ED, Yung R, Tripathy D, Nanda R, Wulfkuhle JD, Brown-Swigart L, Gallagher RI, Helsten T, Roesch E, Ewing CA, Alvarado M, Crane EP, Buxton M, Clennell JL, Paoloni M, Asare SM, Wilson A, Hirst GL, Singhrao R, Steeg K, Asare A, Matthews JB, Berry S, Sanil A, Melisko M, Perlmutter J, Rugo HS, Schwab RB, Symmans WF, Hylton NM, Berry DA, Esserman LJ, DeMichele AM. PMID: 34741023; PMCID: PMC8571284.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    9. Should Sentinel Lymph Node Biopsy Status Guide Adjuvant Radiation Therapy in Patients With Merkel Cell Carcinoma? Adv Radiat Oncol. 2021 Nov-Dec; 6(6):100764. Ahmad TR, Vasudevan HN, Lazar AA, Chan JW, George JR, Alvarado MD, Yu SS, Daud A, Yom SS. PMID: 34485762; PMCID: PMC8408430.
      View in: PubMed   Mentions: 1  
    10. Positive margins after mastectomy in patients with invasive lobular carcinoma of the breast: Incidence and management strategies. Am J Surg. 2022 04; 223(4):699-704. Hewitt KC, Miller P, Piper M, Prionas N, Son JD, Alvarado M, Esserman LJ, Wong JM, Ewing C, Mukhtar RA. PMID: 34148670.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    11. Modulation of the immune microenvironment of high-risk ductal carcinoma in situ by intralesional pembrolizumab injection. NPJ Breast Cancer. 2021 May 25; 7(1):59. Glencer AC, Wong JM, Hylton NM, Krings G, McCune E, Rothschild HT, Loveday TA, Alvarado MD, Esserman LJ, Campbell MJ, Campbell MJ. PMID: 34035311; PMCID: PMC8149838.
      View in: PubMed   Mentions: 2  
    12. New clinical and biological insights from the international TARGIT-A randomised trial of targeted intraoperative radiotherapy during lumpectomy for breast cancer. Br J Cancer. 2021 08; 125(3):380-389. Vaidya JS, Bulsara M, Baum M, Wenz F, Massarut S, Pigorsch S, Alvarado M, Douek M, Saunders C, Flyger H, Eiermann W, Brew-Graves C, Williams NR, Potyka I, Roberts N, Bernstein M, Brown D, Sperk E, Laws S, Sütterlin M, Corica T, Lundgren S, Holmes D, Vinante L, Bozza F, Pazos M, Blanc-Onfroy ML, Gruber G, Polkowski W, Dedes KJ, Niewald M, Blohmer J, McReady D, Hoefer R, Kelemen P, Petralia G, Falzon M, Joseph D, Tobias JS. PMID: 34035435; PMCID: PMC8329051.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    13. Accuracy of breast MRI in evaluating nodal status after neoadjuvant therapy in invasive lobular carcinoma. NPJ Breast Cancer. 2021 Mar 05; 7(1):25. Abel MK, Greenwood H, Kelil T, Guo R, Brabham C, Hylton N, Wong J, Alvarado M, Ewing C, Esserman LJ, Boughey JC, Mukhtar RA. PMID: 33674614; PMCID: PMC7935955.
      View in: PubMed   Mentions: 5  
    14. Intraoperative radiotherapy for breast cancer: powerful evidence to change practice. Nat Rev Clin Oncol. 2021 03; 18(3):187-188. Vaidya JS, Bulsara M, Baum M, Alvarado M, Bernstein M, Massarut S, Saunders C, Sperk E, Wenz F, Tobias JS, TARGIT-A investigators. PMID: 33495552; PMCID: PMC7830040.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    15. In Regard to Polgar et al. Int J Radiat Oncol Biol Phys. 2021 07 01; 110(3):905-907. Vaidya JS, Bulsara M, Sperk E, Massarut S, Douek M, Alvarado M, Pigorsch S, Holmes D, Bernstein M, Saunders C, Flyger H, Joseph D, Wenz F, Tobias JS, TARGIT-A Investigators. PMID: 33640419.
      View in: PubMed   Mentions:    Fields:    
    16. Accuracy of sentinel lymph node biopsy in invasive lobular carcinoma of the breast: Factors associated with false negatives. Breast J. 2021 04; 27(4):406-408. Mukhtar RA, Brabham CE, Guo R, Abel MK, Wong J, Ewing C, Esserman LJ, Alvarado M. PMID: 33486856.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    17. Correction to: SentimagIC: A Non-inferiority Trial Comparing Superparamagnetic Iron Oxide Versus Technetium-99m and Blue Dye in the Detection of Axillary Sentinel Nodes in Patients with Early-Stage Breast Cancer. Ann Surg Oncol. 2020 Dec; 27(Suppl 3):979. Alvarado MD, Mittendorf EA, Teshome M, Thompson AM, Bold RJ, Gittleman MA, Beitsch PD, Blair SL, Kivilaid K, Harmer QJ, Hunt KK. PMID: 32514803.
      View in: PubMed   Mentions:    Fields:    
    18. Oncological Outcomes of Total Skin-Sparing Mastectomy for Invasive Lobular Carcinoma of the Breast: A 20-Year Institutional Experience. Ann Surg Oncol. 2021 May; 28(5):2555-2560. Son JD, Piper M, Hewitt K, Alvarado M, Esserman LJ, Ewing C, Wong JM, Mukhtar RA. PMID: 33025355.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Layilin augments integrin activation to promote antitumor immunity. J Exp Med. 2020 09 07; 217(9). Mahuron KM, Moreau JM, Glasgow JE, Boda DP, Pauli ML, Gouirand V, Panjabi L, Grewal R, Luber JM, Mathur AN, Feldman RM, Shifrut E, Mehta P, Lowe MM, Alvarado MD, Marson A, Singer M, Wells J, Jupp R, Daud AI, Rosenblum MD. PMID: 32539073; PMCID: PMC7478725.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    20. Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial. BMJ. 2020 08 19; 370:m2836. Vaidya JS, Bulsara M, Baum M, Wenz F, Massarut S, Pigorsch S, Alvarado M, Douek M, Saunders C, Flyger HL, Eiermann W, Brew-Graves C, Williams NR, Potyka I, Roberts N, Bernstein M, Brown D, Sperk E, Laws S, Sütterlin M, Corica T, Lundgren S, Holmes D, Vinante L, Bozza F, Pazos M, Le Blanc-Onfroy M, Gruber G, Polkowski W, Dedes KJ, Niewald M, Blohmer J, McCready D, Hoefer R, Kelemen P, Petralia G, Falzon M, Joseph DJ, Tobias JS. PMID: 32816842; PMCID: PMC7500441.
      View in: PubMed   Mentions: 74     Fields:    Translation:Humans
    21. Evaluating the impact of axillary dissection on recurrence-free survival by extent of nodal disease in invasive lobular carcinoma of the breast. Breast Cancer Res Treat. 2020 Oct; 183(3):661-667. Abel MK, Fahrner-Scott K, Wong J, Alvarado M, Ewing C, Esserman LJ, Park C, Mukhtar RA. PMID: 32696313.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Effect of Delayed Targeted Intraoperative Radiotherapy vs Whole-Breast Radiotherapy on Local Recurrence and Survival: Long-term Results From the TARGIT-A Randomized Clinical Trial in Early Breast Cancer. JAMA Oncol. 2020 07 01; 6(7):e200249. Vaidya JS, Bulsara M, Saunders C, Flyger H, Tobias JS, Corica T, Massarut S, Wenz F, Pigorsch S, Alvarado M, Douek M, Eiermann W, Brew-Graves C, Williams N, Potyka I, Roberts N, Bernstein M, Brown D, Sperk E, Laws S, Sütterlin M, Lundgren S, Holmes D, Vinante L, Bozza F, Pazos M, Le Blanc-Onfroy M, Gruber G, Polkowski W, Dedes KJ, Niewald M, Blohmer J, McCready D, Hoefer R, Kelemen P, Petralia G, Falzon M, Baum M, Joseph D. PMID: 32239210; PMCID: PMC7348682.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCTClinical Trials
    23. Breast conservation therapy versus mastectomy in the surgical management of invasive lobular carcinoma measuring 4 cm or greater. Am J Surg. 2021 01; 221(1):32-36. Abel MK, Brabham CE, Guo R, Fahrner-Scott K, Wong J, Alvarado M, Ewing C, Esserman LJ, Mukhtar RA. PMID: 32622509; PMCID: PMC7736057.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Tumor Immune Profiling-Based Neoadjuvant Immunotherapy for Locally Advanced Melanoma. Ann Surg Oncol. 2020 Oct; 27(11):4122-4130. Levine LS, Mahuron KM, Tsai KK, Wu C, Mattis DM, Pauli ML, Oglesby A, Lee JC, Spitzer MH, Krummel MF, Algazi AP, Rosenblum MD, Alvarado M, Daud AI. PMID: 32488521; PMCID: PMC8317618.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    25. Mitotic score and pleomorphic histology in invasive lobular carcinoma of the breast: impact on disease-free survival. Breast Cancer Res Treat. 2020 May; 181(1):23-29. Mukhtar RA, Krings G, Chen YY, Mamounas ME, Fahrner-Scott K, Wong J, Alvarado M, Ewing C, Esserman LJ, Rugo H. PMID: 32240457.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. Success rates of re-excision after positive margins for invasive lobular carcinoma of the breast. NPJ Breast Cancer. 2019; 5:29. Piper ML, Wong J, Fahrner-Scott K, Ewing C, Alvarado M, Esserman LJ, Mukhtar RA. PMID: 31508489; PMCID: PMC6731236.
      View in: PubMed   Mentions: 15  
    27. SentimagIC: A Non-inferiority Trial Comparing Superparamagnetic Iron Oxide Versus Technetium-99m and Blue Dye in the Detection of Axillary Sentinel Nodes in Patients with Early-Stage Breast Cancer. Ann Surg Oncol. 2019 Oct; 26(11):3510-3516. Alvarado MD, Mittendorf EA, Teshome M, Thompson AM, Bold RJ, Gittleman MA, Beitsch PD, Blair SL, Kivilaid K, Harmer QJ, Hunt KK. PMID: 31297674.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    28. Feasibility of Magnetic Seeds for Preoperative Localization of Axillary Lymph Nodes in Breast Cancer Treatment. AJR Am J Roentgenol. 2019 10; 213(4):953-957. Greenwood HI, Wong JM, Mukhtar RA, Alvarado MD, Price ER. PMID: 31166765.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    29. Synchronous Detection of Circulating Tumor Cells in Blood and Disseminated Tumor Cells in Bone Marrow Predicts Adverse Outcome in Early Breast Cancer. Clin Cancer Res. 2019 09 01; 25(17):5388-5397. Magbanua MJM, Yau C, Wolf DM, Lee JS, Chattopadhyay A, Scott JH, Bowlby-Yoder E, Hwang ES, Alvarado M, Ewing CA, Delson AL, Van't Veer LJ, Esserman L, Park JW. PMID: 31142502; PMCID: PMC6726564.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    30. Erratum: Author Correction: Surgical Standards for Management of the Axilla in Breast Cancer Clinical Trials with Pathological Complete Response Endpoint. NPJ Breast Cancer. 2019; 5:2. Boughey JC, Alvarado MD, Lancaster RB, Symmans WF, Mukhtar R, Wong JM, Ewing CA, Potter DA, Tuttle TM, Hieken TJ, Carter JM, Jakub JW, Kaplan HG, Buchanan CL, Jaskowiak NT, Sattar HA, Mueller J, Nanda R, Isaacs CJ, Pohlmann PR, Lynce F, Tousimis EA, Zeck JC, Lee MC, Lang JE, Mhawech-Fauceglia P, Rao R, Taback B, Goodellas C, Chen M, Kalinsky KM, Hibshoosh H, Killelea B, Sanft T, Hirst GL, Asare S, Matthews JB, Perlmutter J, Esserman LJ, I-SPY2 Investigators. PMID: 30675512; PMCID: PMC6315027.
      View in: PubMed   Mentions:
    31. Surgical Standards for Management of the Axilla in Breast Cancer Clinical Trials with Pathological Complete Response Endpoint. NPJ Breast Cancer. 2018; 4:26. Boughey JC, Alvarado MD, Lancaster RB, Fraser Symmans W, Mukhtar R, Wong JM, Ewing CA, Potter DA, Tuttle TM, Hieken TJ, Carter JM, Jakub JW, Kaplan HG, Buchanan CL, Jaskowiak NT, Sattar HA, Mueller J, Nanda R, Isaacs CJ, Pohlmann PR, Lynce F, Tousimis EA, Zeck JC, Lee MC, Lang JE, Mhawech-Fauceglia P, Rao R, Taback B, Chen M, Kalinsky KM, Hibshoosh H, Killelea B, Sanft T, Hirst GL, Asare S, Matthews JB, Perlmutter J, Esserman LJ, and I-SPY 2 Investigators. PMID: 30131975; PMCID: PMC6098077.
      View in: PubMed   Mentions: 6  
    32. Breast Conservation and Negative Margins in Invasive Lobular Carcinoma: The Impact of Oncoplastic Surgery and Shave Margins in 358 Patients. Ann Surg Oncol. 2018 Oct; 25(11):3165-3170. Mukhtar RA, Wong J, Piper M, Zhu Z, Fahrner-Scott K, Mamounas M, Sbitany H, Alvarado M, Foster R, Ewing C, Esserman L. PMID: 30054826.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    33. A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments. Nat Med. 2018 08; 24(8):1178-1191. Barry KC, Hsu J, Broz ML, Cueto FJ, Binnewies M, Combes AJ, Nelson AE, Loo K, Kumar R, Rosenblum MD, Alvarado MD, Wolf DM, Bogunovic D, Bhardwaj N, Daud AI, Ha PK, Ryan WR, Pollack JL, Samad B, Asthana S, Chan V, Krummel MF. PMID: 29942093; PMCID: PMC6475503.
      View in: PubMed   Mentions: 423     Fields:    Translation:HumansCells
    34. Initial Clinical Experience With an Inducible Magnetic Seed System for Preoperative Breast Lesion Localization. AJR Am J Roentgenol. 2018 Apr; 210(4):913-917. Price ER, Khoury AL, Esserman LJ, Joe BN, Alvarado MD. PMID: 29446680.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    35. Complications After Total Skin-Sparing Mastectomy and Expander-Implant Reconstruction: Effects of Radiation Therapy on the Stages of Reconstruction. Ann Plast Surg. 2018 Jan; 80(1):10-13. Peled AW, Sears M, Wang F, Foster RD, Alvarado M, Wong J, Ewing CA, Sbitany H, Esserman LJ, Fowble B. PMID: 28671888.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    36. Best practices for multidisciplinary integration of a DCIS genomic assay into clinical practice. J Surg Oncol. 2017 Dec; 116(8):1016-1020. Alvarado M, Lucci A, Manders J. PMID: 28833159.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    37. Indications for Postmastectomy Radiation After Neoadjuvant Chemotherapy in ypN0 and ypN1-3 Axillary Node-Positive Women. Clin Breast Cancer. 2018 02; 18(1):e107-e113. Fowble B, Jairam AK, Wang F, Peled A, Alvarado M, Ewing C, Esserman L, Park C, Lazar A. PMID: 28830795.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    38. Partially exhausted tumor-infiltrating lymphocytes predict response to combination immunotherapy. JCI Insight. 2017 Jul 20; 2(14). Loo K, Tsai KK, Mahuron K, Liu J, Pauli ML, Sandoval PM, Nosrati A, Lee J, Chen L, Hwang J, Levine LS, Krummel MF, Algazi AP, Pampaloni M, Alvarado MD, Rosenblum MD, Daud AI. PMID: 28724802; PMCID: PMC5518562.
      View in: PubMed   Mentions: 33     Fields:    
    39. Tumor immune profiling predicts response to anti-PD-1 therapy in human melanoma. J Clin Invest. 2016 09 01; 126(9):3447-52. Daud AI, Loo K, Pauli ML, Sanchez-Rodriguez R, Sandoval PM, Taravati K, Tsai K, Nosrati A, Nardo L, Alvarado MD, Algazi AP, Pampaloni MH, Lobach IV, Hwang J, Pierce RH, Gratz IK, Krummel MF, Rosenblum MD. PMID: 27525433; PMCID: PMC5004965.
      View in: PubMed   Mentions: 267     Fields:    Translation:HumansCells
    40. Prognostic Impact of 21-Gene Recurrence Score in Patients With Stage IV Breast Cancer: TBCRC 013. J Clin Oncol. 2016 07 10; 34(20):2359-65. King TA, Lyman JP, Gonen M, Voci A, De Brot M, Boafo C, Sing AP, Hwang ES, Alvarado MD, Liu MC, Boughey JC, McGuire KP, Van Poznak CH, Jacobs LK, Meszoely IM, Krontiras H, Babiera GV, Norton L, Morrow M, Hudis CA. PMID: 27001590; PMCID: PMC4981976.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    41. Less Is More: The Evolving Surgical Approach to Breast Cancer. Am Soc Clin Oncol Educ Book. 2016; 35:e5-e10. Esserman L, Gallant E, Alvarado M. PMID: 27249759.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    42. Tissue Expander Reconstruction After Total Skin-Sparing Mastectomy: Defining the Effects of Coverage Technique on Nipple/Areola Preservation. Ann Plast Surg. 2016 Jan; 77(1):17-24. Sbitany H, Wang F, Peled AW, Alvarado M, Ewing CA, Esserman LJ, Foster RD. PMID: 25057918.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    43. The Impact of Radiation Therapy, Lymph Node Dissection, and Hormonal Therapy on Outcomes of Tissue Expander-Implant Exchange in Prosthetic Breast Reconstruction. Plast Reconstr Surg. 2016 Jan; 137(1):1-9. Wang F, Peled AW, Chin R, Fowble B, Alvarado M, Ewing C, Esserman L, Foster R, Sbitany H. PMID: 26368331.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    44. Sentinel Lymph Node Mapping in Post-Mastectomy Chest Wall Recurrences: Influence on Radiation Treatment Fields and Outcome. Ann Surg Oncol. 2016 Mar; 23(3):715-21. Johnson J, Esserman L, Ewing C, Alvarado M, Park C, Fowble B. PMID: 26714943.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    45. A Prospective Comparison of the 21-Gene Recurrence Score and the PAM50-Based Prosigna in Estrogen Receptor-Positive Early-Stage Breast Cancer. Adv Ther. 2015 Dec; 32(12):1237-47. Alvarado MD, Prasad C, Rothney M, Cherbavaz DB, Sing AP, Baehner FL, Svedman C, Markopoulos CJ. PMID: 26610383; PMCID: PMC4679783.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    46. Negative Genetic Testing Does Not Deter Contralateral Prophylactic Mastectomy in Younger Patients with Greater Family Histories of Breast Cancer. Ann Surg Oncol. 2015 Oct; 22(10):3338-45. Wang F, Amara D, Peled AW, Sbitany H, Foster RD, Ewing CA, Alvarado M, Esserman LJ. PMID: 26215194.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    47. In Regard to Hepel and Wazer. Int J Radiat Oncol Biol Phys. 2015 Aug 01; 92(5):953-954. Vaidya JS, Bulsara M, Wenz F, Joseph D, Saunders C, Massarut S, Flyger H, Eiermann W, Alvarado M, Esserman L, Falzon M, Brew-Graves C, Potyka I, Tobias JS, Baum M. PMID: 26194663.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    48. In Regard to Hepel and Wazer. Int J Radiat Oncol Biol Phys. 2015 Aug 01; 92(5):955-957. Harris EE, Small W, Holmes D, Grobmyer S, Pavord D, Rice JS, Alvarado M. PMID: 26194665.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    49. Expanding the Indications for Total Skin-Sparing Mastectomy: Is It Safe for Patients with Locally Advanced Disease? Ann Surg Oncol. 2016 Jan; 23(1):87-91. Peled AW, Wang F, Foster RD, Alvarado M, Ewing CA, Sbitany H, Esserman LJ. PMID: 26170194.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    50. Tumor Involvement of the Nipple in Total Skin-Sparing Mastectomy: Strategies for Management. Ann Surg Oncol. 2015 Nov; 22(12):3803-8. Amara D, Peled AW, Wang F, Ewing CA, Alvarado M, Esserman LJ. PMID: 26023040.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    51. The impact of genomic testing on the recommendation for radiation therapy in patients with ductal carcinoma in situ: A prospective clinical utility assessment of the 12-gene DCIS score™ result. J Surg Oncol. 2015 Jun; 111(8):935-40. Alvarado M, Carter DL, Guenther JM, Hagans J, Lei RY, Leonard CE, Manders J, Sing AP, Broder MS, Cherepanov D, Chang E, Eagan M, Hsiao W, Schultz MJ. PMID: 26031501.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    52. Rates of Reconstruction Failure in Patients Undergoing Immediate Reconstruction With Tissue Expanders and/or Implants and Postmastectomy Radiation Therapy. Int J Radiat Oncol Biol Phys. 2015 Jul 01; 92(3):634-41. Fowble B, Park C, Wang F, Peled A, Alvarado M, Ewing C, Esserman L, Foster R, Sbitany H, Hanlon A. PMID: 25936815.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    53. Pride, Prejudice, or Science: Attitudes Towards the Results of the TARGIT-A Trial of Targeted Intraoperative Radiation Therapy for Breast Cancer. Int J Radiat Oncol Biol Phys. 2015 Jul 01; 92(3):491-7. Vaidya JS, Bulsara M, Wenz F, Joseph D, Saunders C, Massarut S, Flyger H, Eiermann W, Alvarado M, Esserman L, Falzon M, Brew-Graves C, Potyka I, Tobias JS, Baum M, TARGIT trialists' group. PMID: 26068479; PMCID: PMC4464618.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    54. The impact of breast mass on outcomes of total skin-sparing mastectomy and immediate tissue expander-based breast reconstruction. Plast Reconstr Surg. 2015 Mar; 135(3):672-679. Wang F, Alvarado M, Ewing C, Esserman L, Foster R, Sbitany H. PMID: 25719689.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    55. Immediate implant-based breast reconstruction following total skin-sparing mastectomy: defining the risk of preoperative and postoperative radiation therapy for surgical outcomes. Plast Reconstr Surg. 2014 Sep; 134(3):396-404. Sbitany H, Wang F, Peled AW, Lentz R, Alvarado M, Ewing CA, Esserman LJ, Fowble B, Foster RD. PMID: 25158699.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    56. Haste makes waste, but lack of urgency is opportunity lost. Breast Cancer Res Treat. 2014 Aug; 147(1):223-4. Esserman L, Hayes M, Alvarado M. PMID: 25062705.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    57. Total skin-sparing mastectomy and immediate breast reconstruction: an evolution of technique and assessment of outcomes. Ann Surg Oncol. 2014 Oct; 21(10):3223-30. Wang F, Peled AW, Garwood E, Fiscalini AS, Sbitany H, Foster RD, Alvarado M, Ewing C, Hwang ES, Esserman LJ. PMID: 25052246.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    58. Immediate implant-based breast reconstruction following total skin-sparing mastectomy in women with a history of augmentation mammaplasty: assessing the safety profile. Plast Reconstr Surg. 2014 Jul; 134(1):1-9. Sbitany H, Wang F, Saeed L, Alvarado M, Ewing CA, Esserman LJ, Foster RD. PMID: 24622575.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    59. Local recurrence rates are low in high-risk neoadjuvant breast cancer in the I-SPY 1 Trial (CALGB 150007/150012; ACRIN 6657). Ann Surg Oncol. 2014 Sep; 21(9):2889-96. Cureton EL, Yau C, Alvarado MD, Krontiras H, Ollila DW, Ewing CA, Monnier S, Esserman LJ. PMID: 24788555; PMCID: PMC4303244.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    60. The current clinical value of the DCIS Score. Oncology (Williston Park). 2014 May; 28 Suppl 2:C2, 1-8, C3. Wood WC, Alvarado M, Buchholz DJ, Hyams D, Hwang S, Manders J, Park C, Solin LJ, White J, Willey S. PMID: 25375000.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    61. Setting a research agenda for ductal carcinoma in situ that meets the current need for change. Ann Intern Med. 2014 Apr 01; 160(7):511-2. Esserman L, Alvarado M. PMID: 24566896.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    62. Abstract 124: outcomes of total skin-sparing mastectomy and reconstruction in 924 breasts over 11 years. Plast Reconstr Surg. 2014 Mar; 133(3 Suppl):139. Wang F, Peled A, Foster R, Wang E, Ewing C, Alvarado M, Esserman L, Sbitany H. PMID: 25942235.
      View in: PubMed   Mentions:    Fields:    
    63. Memory regulatory T cells reside in human skin. J Clin Invest. 2014 Mar; 124(3):1027-36. Sanchez Rodriguez R, Pauli ML, Neuhaus IM, Yu SS, Arron ST, Harris HW, Yang SH, Anthony BA, Sverdrup FM, Krow-Lucal E, MacKenzie TC, Johnson DS, Meyer EH, Löhr A, Hsu A, Koo J, Liao W, Gupta R, Debbaneh MG, Butler D, Huynh M, Levin EC, Leon A, Hoffman WY, McGrath MH, Alvarado MD, Ludwig CH, Truong HA, Maurano MM, Gratz IK, Abbas AK, Rosenblum MD. PMID: 24509084; PMCID: PMC3934172.
      View in: PubMed   Mentions: 162     Fields:    Translation:HumansAnimalsCells
    64. Patient preferences regarding intraoperative versus external beam radiotherapy following breast-conserving surgery. Breast Cancer Res Treat. 2014 Jan; 143(1):135-40. Alvarado MD, Conolly J, Park C, Sakata T, Mohan AJ, Harrison BL, Hayes M, Esserman LJ, Ozanne EM. PMID: 24292868.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    65. Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial. Lancet. 2014 Feb 15; 383(9917):603-13. Vaidya JS, Wenz F, Bulsara M, Tobias JS, Joseph DJ, Keshtgar M, Flyger HL, Massarut S, Alvarado M, Saunders C, Eiermann W, Metaxas M, Sperk E, Sütterlin M, Brown D, Esserman L, Roncadin M, Thompson A, Dewar JA, Holtveg HM, Pigorsch S, Falzon M, Harris E, Matthews A, Brew-Graves C, Potyka I, Corica T, Williams NR, Baum M, TARGIT trialists' group. PMID: 24224997.
      View in: PubMed   Mentions: 263     Fields:    Translation:Humans
    66. Total skin-sparing mastectomy in BRCA mutation carriers. Ann Surg Oncol. 2014 Jan; 21(1):37-41. Peled AW, Irwin CS, Hwang ES, Ewing CA, Alvarado M, Esserman LJ. PMID: 23982256.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    67. Cost-effectiveness analysis of intraoperative radiation therapy for early-stage breast cancer. Ann Surg Oncol. 2013 Sep; 20(9):2873-80. Alvarado MD, Mohan AJ, Esserman LJ, Park CC, Harrison BL, Howe RJ, Thorsen C, Ozanne EM. PMID: 23812769.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    68. Author's reply to Lamy. J Natl Cancer Inst. 2013 Jan 16; 105(2):149-50. Hornberger J, Gradishar WJ, Alvarado MD, Chien R, Yu TM, Gutierrez HR. PMID: 23441341.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    69. Clinical validity/utility, change in practice patterns, and economic implications of risk stratifiers to predict outcomes for early-stage breast cancer: a systematic review. J Natl Cancer Inst. 2012 Jul 18; 104(14):1068-79. Hornberger J, Alvarado MD, Rebecca C, Gutierrez HR, Yu TM, Gradishar WJ. PMID: 22767204.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    70. Evaluating the feasibility of extended partial mastectomy and immediate reduction mammoplasty reconstruction as an alternative to mastectomy. Ann Surg. 2012 Jun; 255(6):1151-7. Chang EI, Peled AW, Foster RD, Lin C, Zeidler KR, Ewing CA, Alvarado M, Hwang ES, Esserman LJ. PMID: 22470069.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    71. The effects of acellular dermal matrix in expander-implant breast reconstruction after total skin-sparing mastectomy: results of a prospective practice improvement study. Plast Reconstr Surg. 2012 Jun; 129(6):901e-908e. Peled AW, Foster RD, Garwood ER, Moore DH, Ewing CA, Alvarado M, Hwang ES, Esserman LJ. PMID: 22634688.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    72. Outcomes after total skin-sparing mastectomy and immediate reconstruction in 657 breasts. Ann Surg Oncol. 2012 Oct; 19(11):3402-9. Warren Peled A, Foster RD, Stover AC, Itakura K, Ewing CA, Alvarado M, Hwang ES, Esserman LJ. PMID: 22526909.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    73. Overdiagnosis and overtreatment of breast cancer. Am Soc Clin Oncol Educ Book. 2012; e40-5. Alvarado M, Ozanne E, Esserman L. PMID: 24451829.
      View in: PubMed   Mentions: 18     Fields:    
    74. The impact of preoperative magnetic resonance imaging on surgical treatment and outcomes for ductal carcinoma in situ. Clin Breast Cancer. 2011 Mar; 11(1):33-8. Itakura K, Lessing J, Sakata T, Heinzerling A, Vriens E, Wisner D, Alvarado M, Esserman L, Ewing C, Hylton N, Hwang ES. PMID: 21421520; PMCID: PMC4508001.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    75. Impact of chemotherapy on postoperative complications after mastectomy and immediate breast reconstruction. Arch Surg. 2010 Sep; 145(9):880-5. Warren Peled A, Itakura K, Foster RD, Hamolsky D, Tanaka J, Ewing C, Alvarado M, Esserman LJ, Hwang ES. PMID: 20855759.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    76. Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial. Lancet. 2010 Jul 10; 376(9735):91-102. Vaidya JS, Joseph DJ, Tobias JS, Bulsara M, Wenz F, Saunders C, Alvarado M, Flyger HL, Massarut S, Eiermann W, Keshtgar M, Dewar J, Kraus-Tiefenbacher U, Sütterlin M, Esserman L, Holtveg HM, Roncadin M, Pigorsch S, Metaxas M, Falzon M, Matthews A, Corica T, Williams NR, Baum M. PMID: 20570343.
      View in: PubMed   Mentions: 226     Fields:    Translation:HumansCTClinical Trials
    77. Is radiation indicated in patients with ductal carcinoma in situ and close or positive mastectomy margins? Int J Radiat Oncol Biol Phys. 2011 May 01; 80(1):25-30. Chan LW, Rabban J, Hwang ES, Bevan A, Alvarado M, Ewing C, Esserman L, Fowble B. PMID: 20646871.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    78. Gene expression profiling of colorectal mucinous adenocarcinomas. Dis Colon Rectum. 2010 Jun; 53(6):936-43. Melis M, Hernandez J, Siegel EM, McLoughlin JM, Ly QP, Nair RM, Lewis JM, Jensen EH, Alvarado MD, Coppola D, Eschrich S, Bloom GC, Yeatman TJ, Shibata D. PMID: 20485009.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    79. Bacteriologic features of surgical site infections following breast surgery. Am J Surg. 2009 Oct; 198(4):529-31. Mukhtar RA, Throckmorton AD, Alvarado MD, Ewing CA, Esserman LJ, Chiu C, Hwang ES. PMID: 19800462.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    80. Prognostic implications of positive nonsentinel lymph nodes removed during selective sentinel lymphadenectomy for breast cancer. Breast J. 2009 May-Jun; 15(3):242-6. Lang JE, Liu LC, Lu Y, Jenkins T, Hwang SE, Esserman LJ, Ewing CA, Alvarado M, Morita E, Treseler P, Leong SP. PMID: 19645778.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    81. Total skin-sparing mastectomy: complications and local recurrence rates in 2 cohorts of patients. Ann Surg. 2009 Jan; 249(1):26-32. Garwood ER, Moore D, Ewing C, Hwang ES, Alvarado M, Foster RD, Esserman LJ. PMID: 19106672.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    82. Is it necessary to harvest additional lymph nodes after resection of the most radioactive sentinel lymph node in breast cancer? J Am Coll Surg. 2008 Dec; 207(6):853-8. Liu LC, Lang JE, Jenkins T, Lu Y, Ewing CA, Hwang SE, Sokol S, Alvarado M, Esserman LJ, Morita E, Treseler P, Leong SP. PMID: 19183531.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    83. Surgery for palliation and treatment of advanced breast cancer. Surg Oncol. 2007 Dec; 16(4):249-57. Alvarado M, Ewing CA, Elyassnia D, Foster RD, Shelley Hwang E. PMID: 17976977.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    84. The value of sentinel lymph node biopsy in the management of head and neck melanoma. J Surg Oncol. 2007 May 01; 95(6):524-5; author reply 523. Alvarado M, Sondak V, Leong PL. PMID: 17221851.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    85. Down-regulation of pro-apoptotic genes is an early event in the progression of malignant melanoma. Ann Surg Oncol. 2007 Apr; 14(4):1416-23. Jensen EH, Lewis JM, McLoughlin JM, Alvarado MD, Daud A, Messina J, Enkemann S, Yeatman TJ, Sondak VK, Riker AI. PMID: 17195911.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    86. Biomarkers predict outcomes following cytoreductive surgery for hepatic metastases from functional carcinoid tumors. Ann Surg Oncol. 2007 Feb; 14(2):780-5. Jensen EH, Kvols L, McLoughlin JM, Lewis JM, Alvarado MD, Yeatman T, Malafa M, Shibata D. PMID: 17146740.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    87. The potential role of gene expression in the management of primary and metastatic colorectal cancer. Cancer Control. 2006 Jan; 13(1):27-31. Alvarado MD, Jensen EH, Yeatman TJ. PMID: 16508623.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
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