GTP-Binding Protein alpha Subunits, G12-G13
"GTP-Binding Protein alpha Subunits, G12-G13" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed family of heterotrimeric GTP-binding protein alpha subunits that signal through interactions with a variety of second messengers as GTPASE-ACTIVATING PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; and HEAT SHOCK PROTEINS. The G12-G13 part of the name is also spelled G12/G13.
| Descriptor ID |
D044365
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| MeSH Number(s) |
D08.811.277.040.330.300.200.100.100 D12.644.360.360.100.100 D12.776.157.325.332.100.100 D12.776.476.375.100.100 D12.776.543.325.100.100
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| Concept/Terms |
GTP-Binding Protein alpha Subunits, G12-G13- GTP-Binding Protein alpha Subunits, G12-G13
- GTP Binding Protein alpha Subunits, G12 G13
- G-Protein, G12-G13 alpha Subunits
- G Protein, G12 G13 alpha Subunits
- G-Protein, G12-G13 alpha Family
- G Protein, G12 G13 alpha Family
GTP-Binding Protein alpha Subunit, G13- GTP-Binding Protein alpha Subunit, G13
- GTP Binding Protein alpha Subunit, G13
- G13 G-Protein
- G-Protein, G13
- G13 G Protein
- G(13) Protein
- Galpha13 Protein
- G-Protein, G13 Subunit
- G Protein, G13 Subunit
- G13 Subunit G-Protein
- Subunit G-Protein, G13
- G13 Protein
- G alpha13 Protein
- alpha13 Protein, G
GTP-Binding Protein alpha Subunit, G12- GTP-Binding Protein alpha Subunit, G12
- GTP Binding Protein alpha Subunit, G12
- G12 alpha Protein
- alpha Protein, G12
- G12 Protein
- Protein, G12
- G-Protein, G12 Subunit
- G Protein, G12 Subunit
- G12 Subunit G-Protein
- Subunit G-Protein, G12
- G alpha12 Protein
- alpha12 Protein, G
- Galpha12 Protein
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Below are MeSH descriptors whose meaning is more general than "GTP-Binding Protein alpha Subunits, G12-G13".
Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Protein alpha Subunits, G12-G13".
This graph shows the total number of publications written about "GTP-Binding Protein alpha Subunits, G12-G13" by people in this website by year, and whether "GTP-Binding Protein alpha Subunits, G12-G13" was a major or minor topic of these publications.
View timeline visualization
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 2 | 3 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 2 | 3 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2011 | 1 | 2 | 3 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 2 | 1 | 3 |
| 2015 | 4 | 1 | 5 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 2 | 4 |
| 2020 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "GTP-Binding Protein alpha Subunits, G12-G13" by people in Profiles.
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Gα12 signaling regulates transcriptional and phenotypic responses that promote glioblastoma tumor invasion. Sci Rep. 2023 12 16; 13(1):22412.
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CD97 promotes spleen dendritic cell homeostasis through the mechanosensing of red blood cells. Science. 2022 02 11; 375(6581):eabi5965.
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Gαs directly drives PDZ-RhoGEF signaling to Cdc42. J Biol Chem. 2020 12 11; 295(50):16920-16928.
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Auto-regulation of Secretory Flux by Sensing and Responding to the Folded Cargo Protein Load in the Endoplasmic Reticulum. Cell. 2019 03 07; 176(6):1461-1476.e23.
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Gβγ signaling to the chemotactic effector P-REX1 and mammalian cell migration is directly regulated by Gαq and Gα13 proteins. J Biol Chem. 2019 01 11; 294(2):531-546.
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Gα12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration. J Clin Invest. 2018 12 03; 128(12):5587-5602.
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A Rapid Method for Directed Gene Knockout for Screening in G0 Zebrafish. Dev Cell. 2018 07 02; 46(1):112-125.e4.
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GPR56/ADGRG1 regulates development and maintenance of peripheral myelin. J Exp Med. 2018 03 05; 215(3):941-961.
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Lack of beta-arrestin signaling in the absence of active G proteins. Nat Commun. 2018 01 23; 9(1):341.
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Gα12 facilitates shortening in human airway smooth muscle by modulating phosphoinositide 3-kinase-mediated activation in a RhoA-dependent manner. Br J Pharmacol. 2017 Dec; 174(23):4383-4395.