Rita Freimanis, MD

Title(s)Professor, Radiology
SchoolSchool of Medicine
Address550 16th Street, #7352
San Francisco CA 94158
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    Collapse Biography 
    Collapse Awards and Honors
    American College of Radiology2003Elected Fellow
    Wake Forest School of Medicine, Radiology 1998  - 2015James L. Quinn III, MD Award For Teaching Excellence
    Wake Forest Radiology 1990Outstanding Resident Award
    American Medical Women’s Association Certificate of Merit 1985Best Female Medical Student, Bowman Gray SOM
    Wake Forest University School of Medicine 1985Alpha Omega Alpha Medical Honor Society

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    Collapse Overview
    Rita Freimanis, MD, is professor of clinical radiology in the Breast Imaging section at the University of California, San Francisco Mount Zion. She obtained her medical degree from Bowman Gray School of Medicine, Winston-Salem, North Carolina in 1985. In 1990, she completed her four-year Diagnostic Radiology residency program at the North Carolina Baptist Hospital/Bowman Gray School of Medicine in Winston-Salem. Before Dr. Freimanis came to UCSF, she was a professor in the department of radiology at Wake Forest University School of Medicine, as well as the previous Section Head of Breast Imaging, Director of the Breast Imaging Fellowship Program, Radiology Residency Program Director and Vice-Chair of Education.

    Dr. Freimanis’ research interests include collaborating with other clinicians and basic scientists in areas related to breast imaging and breast cancer. She has experience in the evaluation of advance technologies such as stereotactic core needle biopsy, Homologous Electrical Differences Analysis (HEDA), Positron Emission Mammography (PEM), and digital mammography, looking at soft­copy versus film display and computer aided detection. Overall, Dr. Freimanis believes in the importance of anticipating needs of the next generation of patients and imagers, and working to maintain top quality breast imaging services for patients.

    Dr. Freimanis was for many years an invited examiner for the American Board of Radiology and clinical image reviewer for the American College of Radiology mammography accreditation program. She has directed over 20 breast cancer and breast imaging CME meetings. She has 9 book chapters, 29 journal articles and over 100 invited presentations.

    Dr. Freimanis provides many years of experience related to breast imaging, and her expertise in breast cancer, radiology, and education is recognized nationally and internationally.

    Breast Imaging

    Breast cancer, breast imaging

    Professional Interests:
    Mammography, breast ultrasound, breast MRI, image­guided breast biopsy, multidiscipline breast cancer approach, breast tomosynthesis

    Education and Training:
    • Medical School: Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, North Carolina
    • Residency: North Carolina Baptist Hospital/Bowman Gray School of Medicine, Winston-Salem

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Identifying Good Candidates for Active Surveillance of Ductal Carcinoma In Situ: Insights from a Large Neoadjuvant Endocrine Therapy Cohort. Cancer Res Commun. 2022 12; 2(12):1579-1589. Glencer AC, Miller PN, Greenwood H, Maldonado Rodas CK, Freimanis R, Basu A, Mukhtar RA, Brabham C, Kim P, Hwang ES, Rosenbluth JM, Hirst GL, Campbell MJ, Borowsky AD, Esserman LJ. PMID: 36970720; PMCID: PMC10035518.
      View in: PubMed   Mentions: 1  Translation:Humans
    2. Abstract B015: MRI features can identify DCIS patients who can be managed with endocrine therapy alone. Cancer Prevention Research. 2022 Dec 1; 15(12_Supplement_1):b015-b015. Rodas RC, Greenwood GH, Freimanis FR, Borowsky BA, Hirst HG, Hylton HN, Esserman EL, Basu BA. .
      View in: Publisher Site   Mentions:
    3. Alveolar soft part sarcoma of the pectoralis mimicking a breast mass: A case report. Human Pathology Reports. 2022 Sep 1; 29:300674. Lu LK, Sieberg SR, Freimanis FR, Greenwood GH, Schwartz SC. .
      View in: Publisher Site   Mentions:
    4. Abstract P3-03-08: Background parenchymal enhancement as an imaging biomarker in neoadjuvant endocrine therapy for DCIS. Cancer Research. 2022 Feb 15; 82(4_Supplement):p3-03-08-p3-03-08. Onishi ON, Newitt ND, Gibbs GJ, Nguyen NA, Freimanis FR, Price PE, Hwang HS, Hylton HN. .
      View in: Publisher Site   Mentions:
    5. Utility and Outcomes of Preoperative Screening Breast MRI for Planned Bilateral Prophylactic Mastectomy in High-Risk Patients. AJR Am J Roentgenol. 2022 02; 218(2):241-248. Taliaferro AS, Price ER, Hayward JH, Wong JM, Balassanian R, Fay JS, Freimanis RI, Joe BN, Lee AY. PMID: 34523953.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    6. Abstract PD5-01: Magnetic resonance imaging insights from an active surveillance cohort of women with DCIS. Cancer Research. 2021 Feb 15; 81(4_Supplement):pd5-01-pd5-01. Greenwood GH, Freimanis FR, Brabham BC, Mukhtar MR, Hirst HG, Kim KP, Liang LA, Esserman EL, Hylton HN, Basu BA. .
      View in: Publisher Site   Mentions:
    7. Abstract PS1-03: Active surveillance for DCIS: Clinical outcomes at 5.6 years mean follow-up. Cancer Research. 2021 Feb 15; 81(4_Supplement):ps1-03-ps1-03. Brabham BC, Mukhtar MR, Liang LA, Kim KP, Hirst HG, Basu BA, Greenwood GH, Freimanis FR, Borowsky BA, Hwang HS, Baehner BR, Krings KG, Hylton HN, Esserman EL. .
      View in: Publisher Site   Mentions:
    8. Commentary on "Comparison of Abbreviated Breast MRI vs Digital Breast Tomosynthesis for Breast Cancer Detection Among Women With Dense Breasts Undergoing Screening". AJR Am J Roentgenol. 2021 01; 216(1):37. Greenwood HI, Freimanis RI. PMID: 32812772.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    9. A case of acute onset gigantomastia in a 20-year-old woman. Clin Imaging. 2020 Dec; 68:57-60. Vyas S, Greenwood HI, Jankowski T, Freimanis RI, Kallianos KG, Henry TS, Strachowski LM. PMID: 32570010.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Current Landscape of Breast Cancer Imaging and Potential Quantitative Imaging Markers of Response in ER-Positive Breast Cancers Treated with Neoadjuvant Therapy. Cancers (Basel). 2020 Jun 09; 12(6). Jones EF, Hathi DK, Freimanis R, Mukhtar RA, Chien AJ, Esserman LJ, Van't Veer LJ, Joe BN, Hylton NM. PMID: 32527022; PMCID: PMC7352259.
      View in: PubMed   Mentions: 6  
    11. Abstract P6-16-06: Improved early stratification of invasive cancer risk using MRI in a ductal carcinoma in-situ short-term active surveillance cohort treated with neoadjuvant endocrine therapy. Cancer Research. 2020 Feb 15; 80(4_Supplement):p6-16-06-p6-16-06. Kim KP, Greenwood GH, Freimanis FR, Hirst HG, Fischer-Colbrie FM, Gibbs GJ, Hylton HN, Yau YC, Hwang HE, Esserman EL, Mukhtar MR. .
      View in: Publisher Site   Mentions:
    12. Microcalcifications Detected at Screening Mammography: Synthetic Mammography and Digital Breast Tomosynthesis versus Digital Mammography. Radiology. 2018 12; 289(3):630-638. Lai YC, Ray KM, Lee AY, Hayward JH, Freimanis RI, Lobach IV, Joe BN. PMID: 30277445.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    13. Screening Mammography in Women 40-49 Years Old: Current Evidence. AJR Am J Roentgenol. 2018 Feb; 210(2):264-270. Ray KM, Joe BN, Freimanis RI, Sickles EA, Hendrick RE. PMID: 29064760.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    14. Clustered Microcysts on Breast Ultrasound: What Is an Appropriate Management Recommendation? AJR Am J Roentgenol. 2017 Dec; 209(6):W395-W399. Greenwood HI, Lee AY, Lobach IV, Carpentier BM, Freimanis RI, Strachowski LM. PMID: 28929806.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    15. Clinical Breast Magnetic Resonance Imaging: Technique, Indications, and Future Applications. Semin Ultrasound CT MR. 2018 Feb; 39(1):45-59. Greenwood HI, Freimanis RI, Carpentier BM, Joe BN. PMID: 29317039.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    16. Value of diagnostic imaging for the symptomatic male breast: Can we avoid unnecessary biopsies? Clin Imaging. 2017 Sep - Oct; 45:86-91. Foo ET, Lee AY, Ray KM, Woodard GA, Freimanis RI, Joe BN. PMID: 28624748.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Breast cancer screening. N C Med J. 2014 Mar-Apr; 75(2):117-20. Freimanis RI, Yacobozzi M. PMID: 24663133.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    18. Abstract 2613: Racial/Ethnic specific polygenic models of breast cancer risk. Epidemiology. 2012 Apr 15; 2613-2613. Thomas TV, Liu LZ, Srinivasan SS, Chung CR, Martin ME, Levine LE, Freimanis FR, Hu HJ. .
      View in: Publisher Site   Mentions:
    19. Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk. Carcinogenesis. 2008 Nov; 29(11):2132-8. Smith TR, Levine EA, Freimanis RI, Akman SA, Allen GO, Hoang KN, Liu-Mares W, Hu JJ. PMID: 18701435; PMCID: PMC2722862.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansCells
    20. Polymorphisms in CYP1B1, GSTM1, GSTT1 and GSTP1, and susceptibility to breast cancer. Oncol Rep. 2008 May; 19(5):1311-21. Van Emburgh BO, Hu JJ, Levine EA, Mosley LJ, Perrier ND, Freimanis RI, Allen GO, Rubin P, Sherrill GB, Shaw CS, Carey LA, Sawyer LR, Miller MS. PMID: 18425393; PMCID: PMC3668546.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    21. The effects of gray scale image processing on digital mammography interpretation performance. Acad Radiol. 2005 May; 12(5):585-95. Cole EB, Pisano ED, Zeng D, Muller K, Aylward SR, Park S, Kuzmiak C, Koomen M, Pavic D, Walsh R, Baker J, Gimenez EI, Freimanis R. PMID: 15866131.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    22. Primary care providers' concerns and recommendations regarding mammography screening for older women. J Cancer Educ. 2005; 20(1):34-8. Sharp PC, Michielutte R, Spangler JG, Cunningham L, Freimanis R. PMID: 15876180.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    23. DNA-repair genetic polymorphisms and breast cancer risk. Cancer Epidemiol Biomarkers Prev. 2003 Nov; 12(11 Pt 1):1200-4. Smith TR, Levine EA, Perrier ND, Miller MS, Freimanis RI, Lohman K, Case LD, Xu J, Mohrenweiser HW, Hu JJ. PMID: 14652281.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    24. Biopsy needle technique and the accuracy of diagnosis of atypical ductal hyperplasia for mammographic abnormalities. Am Surg. 2003 Sep; 69(9):757-62; discussion 762. Zhao L, Freimanis R, Bergman S, Shen P, Perrier ND, Lesko N, Pulaski T, Pulaski S, Carr JJ, Levine EA. PMID: 14509322.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    25. Method for combined FDG-PET and radiographic imaging of primary breast cancers. Breast J. 2003 May-Jun; 9(3):163-6. Adler LP, Weinberg IN, Bradbury MS, Levine EA, Lesko NM, Geisinger KR, Berg WA, Freimanis RI. PMID: 12752623.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    26. Reported pain following mammography screening. Arch Intern Med. 2003 Apr 14; 163(7):833-6. Sharp PC, Michielutte R, Freimanis R, Cunningham L, Spangler J, Burnette V. PMID: 12695274.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    27. Positron emission mammography: initial clinical results. Ann Surg Oncol. 2003 Jan-Feb; 10(1):86-91. Levine EA, Freimanis RI, Perrier ND, Morton K, Lesko NM, Bergman S, Geisinger KR, Williams RC, Sharpe C, Zavarzin V, Weinberg IN, Stepanov PY, Beylin D, Lauckner K, Doss M, Lovelace J, Adler LP. PMID: 12513966.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    28. Requirements for effective functional breast imaging. Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment. 2003 Jan 1; 497(1):98-104. Weinberg WI, Zawarzin ZV, Adler AL, Pani PR, DeVincentis DG, Khalkhali KI, Vargas VH, Venegas VR, Kim KS, Bakale BG, Levine LE, Perrier PN, Freimanis FR, Lesko LN, Newman ND, Geisinger GK, Berg BW, Masood MS. .
      View in: Publisher Site   Mentions:
    29. Diagnostic accuracy of digital mammography in patients with dense breasts who underwent problem-solving mammography: effects of image processing and lesion type. Radiology. 2003 Jan; 226(1):153-60. Cole EB, Pisano ED, Kistner EO, Muller KE, Brown ME, Feig SA, Jong RA, Maidment AD, Staiger MJ, Kuzmiak CM, Freimanis RI, Lesko N, Rosen EL, Walsh R, Williford M, Braeuning MP. PMID: 12511684.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    30. Interpretation of digital mammograms: comparison of speed and accuracy of soft-copy versus printed-film display. Radiology. 2002 May; 223(2):483-8. Pisano ED, Cole EB, Kistner EO, Muller KE, Hemminger BM, Brown ML, Johnston RE, Kuzmiak CM, Braeuning MP, Freimanis RI, Soo MS, Baker JA, Walsh R. PMID: 11997557.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    31. The Breast Cancers We Miss. Contemporary Diagnostic Radiology. 2001 Apr 1; 24(8):1-9. Freimanis FR, Lesko LN. .
      View in: Publisher Site   Mentions:
    32. Stereotactic localization of breast lesions: how it works and methods to improve accuracy. Radiographics. 2001 Mar-Apr; 21(2):463-73. Carr JJ, Hemler PF, Halford PW, Freimanis RI, Choplin RH, Chen MY. PMID: 11259709.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    33. A controlled evaluation of tuned-aperture computed tomography applied to digital spot mammography. J Digit Imaging. 2000 May; 13(2):90-7. Webber RL, Underhill HR, Freimanis RI. PMID: 10843254; PMCID: PMC3453191.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    34. A novel fuzzy logic approach to microcalcification detection. Information Sciences. 1998 Nov 1; 111(1-4):189-205. Cheng CH, Chen CJ, Freimanis FR, Jiang JX. .
      View in: Publisher Site   Mentions:
    35. A novel approach to microcalcification detection using fuzzy logic technique. IEEE Trans Med Imaging. 1998 Jun; 17(3):442-50. Cheng HD, Lui YM, Freimanis RI. PMID: 9735907.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    36. Appraising pulmonary edema using supine chest roentgenograms in ventilated patients. Am J Respir Crit Care Med. 1998 May; 157(5 Pt 1):1600-8. Thomason JW, Ely EW, Chiles C, Ferretti G, Freimanis RI, Haponik EF. PMID: 9603144.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    37. Stereotactic localization of breast lesions: How it works and methods for improving accuracy. Academic Radiology. 1997 Dec 1; 4(12):862-863. Carr CJ, Hemler HP, Freimanis FR, Choplin CR, Halford HP. .
      View in: Publisher Site   Mentions:
    38. Chest X-ray changes in air space disease are associated with parameters of mechanical ventilation in ICU patients. Am J Respir Crit Care Med. 1996 Nov; 154(5):1543-50. Ely EW, Johnson MM, Chiles C, Rushing JT, Bowton DL, Freimanis RI, Choplin RH, Haponik EF. PMID: 8912778.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    39. Abdominal mass in a four-year-old boy. Invest Radiol. 1990 Sep; 25(9):1058-60. Murphy JS, Freimanis RI, Harmon BH. PMID: 2211051.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    40. The effect of 'irrelevant' IgG protein selection on target uptake ratios of radiolabeled antibodies. Invest Radiol. 1988 Jul; 23(7):537-9. Freimanis R, Zoghbi SS, Gottschalk A. PMID: 3170144.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
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