Sara Suliman • UCSF Profiles

Sara Suliman, PhD, MPH

Title(s)	Assistant Professor, Medicine
School	School of Medicine
Address	2540 23rd Street, #3400 San Francisco CA 94110
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Biography

Education and Training

University of Guelph, Guelph, Canada	BSc	06/2006	Biomedical Sciences
University of Toronto, Toronto, Canada	PhD	06/2013	Immunology
University of Waterloo, Waterloo, Canada	MPH	10/2017	Public Health

Overview

Tuberculosis (TB) disease, caused by infection with the intracellular pathogen Mycobacterium tuberculosis (Mtb) remains a leading cause of mortality globally. Interestingly, only 5-10% of Mtb-exposed individuals are estimated to develop active TB in their lifetime, thus posing host-specific factors as mediators of risk of progression to disease. These host factors include several defects in innate and adaptive immunity, metabolic dysregulation, co-infections and comorbidities, and genetic polymorphisms that could mediate susceptibility to TB disease. The focus of the Suliman laboratory is to generate hypotheses from systems biology approaches, such as genome-wide association studies, transcriptional and metabolomic profiling, and expression quantitative trait loci, to identify candidate TB risk pathways and functionally evaluate their roles in TB progression.

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Predicting Pediatric Tuberculosis: The Need for Age-Specific Host Biosignatures. Clin Infect Dis. 2023 08 14; 77(3):450-452. Suliman S, Jaganath D, DiNardo A. PMID: 37144361; PMCID: PMC10425193.

View in: PubMed Mentions: Fields:
Com Communicable Diseases
Translation:Humans
BCG: From veins to correlates. Cell Host Microbe. 2023 06 14; 31(6):921-923. Suliman S. PMID: 37321176.

View in: PubMed Mentions: 1 Fields:
Mic Microbiology
Translation:Animals Cells PHPublic Health
Evaluation of the Access Bio CareStart rapid SARS-CoV-2 antigen test in asymptomatic individuals tested at a community mass-testing program in Western Massachusetts. Sci Rep. 2022 Dec 09; 12(1):21338. Suliman S, Matias WR, Fulcher IR, Molano FJ, Collins S, Uceta E, Zhu J, Paxton RM, Gonsalves SF, Harden MV, Fisher M, Meldrim J, Gabriel S, Franke MF, Hung DT, Smole SC, Madoff LC, Ivers LC. PMID: 36494424.

View in: PubMed Mentions: 4 Fields:
Sci Science
Translation:Humans Cells PHPublic Health
Dual TCR-α Expression on Mucosal-Associated Invariant T Cells as a Potential Confounder of TCR Interpretation. J Immunol. 2022 03 15; 208(6):1389-1395. Suliman S, Kjer-Nielsen L, Iwany SK, Lopez Tamara K, Loh L, Grzelak L, Kedzierska K, Ocampo TA, Corbett AJ, McCluskey J, Rossjohn J, León SR, Calderon R, Lecca-Garcia L, Murray MB, Moody DB, Van Rhijn I. PMID: 35246495; PMCID: PMC9359468.

View in: PubMed Mentions: 4 Fields:
All Allergy and Immunology
Translation:Humans Cells
Evaluation of serological lateral flow assays for severe acute respiratory syndrome coronavirus-2. BMC Infect Dis. 2021 Jun 16; 21(1):580. Trombetta BA, Kandigian SE, Kitchen RR, Grauwet K, Webb PK, Miller GA, Jennings CG, Jain S, Miller S, Kuo Y, Sweeney T, Gilboa T, Norman M, Simmons DP, Ramirez CE, Bedard M, Fink C, Ko J, De León Peralta EJ, Watts G, Gomez-Rivas E, Davis V, Barilla RM, Wang J, Cunin P, Bates S, Morrison-Smith C, Nicholson B, Wong E, El-Mufti L, Kann M, Bolling A, Fortin B, Ventresca H, Zhou W, Pardo S, Kwock M, Hazra A, Cheng L, Ahmad QR, Toombs JA, Larson R, Pleskow H, Luo NM, Samaha C, Pandya UM, De Silva P, Zhou S, Ganhadeiro Z, Yohannes S, Gay R, Slavik J, Mukerji SS, Jarolim P, Walt DR, Carlyle BC, Ritterhouse LL, Suliman S. PMID: 34134647; PMCID: PMC8206878.

View in: PubMed Mentions: 10 Fields:
Com Communicable Diseases
Translation:Humans Cells
Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease. Nat Immunol. 2021 06; 22(6):781-793. Nathan A, Beynor JI, Baglaenko Y, Suliman S, Ishigaki K, Asgari S, Huang CC, Luo Y, Zhang Z, Lopez K, Lindestam Arlehamn CS, Ernst JD, Jimenez J, Calderón RI, Lecca L, Van Rhijn I, Moody DB, Murray MB, Raychaudhuri S. PMID: 34031617; PMCID: PMC8162307.

View in: PubMed Mentions: 31 Fields:
All Allergy and Immunology
Translation:Humans Cells
Peripheral Blood Mucosal-Associated Invariant T Cells in Tuberculosis Patients and Healthy Mycobacterium tuberculosis-Exposed Controls. J Infect Dis. 2020 08 17; 222(6):995-1007. Suliman S, Gela A, Mendelsohn SC, Iwany SK, Tamara KL, Mabwe S, Bilek N, Darboe F, Fisher M, Corbett AJ, Kjer-Nielsen L, Eckle SBG, Huang CC, Zhang Z, Lewinsohn DM, McCluskey J, Rossjohn J, Hatherill M, León SR, Calderon RI, Lecca L, Murray M, Scriba TJ, Van Rhijn I, Moody DB. PMID: 32267943; PMCID: PMC7430171.

View in: PubMed Mentions: 13 Fields:
Com Communicable Diseases
Translation:Humans Cells PHPublic Health
MR1-Independent Activation of Human Mucosal-Associated Invariant T Cells by Mycobacteria. J Immunol. 2019 12 01; 203(11):2917-2927. Suliman S, Murphy M, Musvosvi M, Gela A, Meermeier EW, Geldenhuys H, Hopley C, Toefy A, Bilek N, Veldsman A, Hanekom WA, Johnson JL, Boom WH, Obermoser G, Huang H, Hatherill M, Lewinsohn DM, Nemes E, Scriba TJ. PMID: 31611259; PMCID: PMC6859375.

View in: PubMed Mentions: 36 Fields:
All Allergy and Immunology
Translation:Humans Cells
Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians. Nat Commun. 2019 08 21; 10(1):3765. Luo Y, Suliman S, Asgari S, Amariuta T, Baglaenko Y, Martínez-Bonet M, Ishigaki K, Gutierrez-Arcelus M, Calderon R, Lecca L, León SR, Jimenez J, Yataco R, Contreras C, Galea JT, Becerra M, Nejentsev S, Nigrovic PA, Moody DB, Murray MB, Raychaudhuri S. PMID: 31434886; PMCID: PMC6704092.

View in: PubMed Mentions: 25 Fields:
Bio Biology Sci Science
Translation:Humans Cells
Four-Gene Pan-African Blood Signature Predicts Progression to Tuberculosis. Am J Respir Crit Care Med. 2018 May 01; 197(9):1198-1208. Suliman S, Thompson EG, Sutherland J, Weiner J, Ota MOC, Shankar S, Penn-Nicholson A, Thiel B, Erasmus M, Maertzdorf J, Duffy FJ, Hill PC, Hughes EJ, Stanley K, Downing K, Fisher ML, Valvo J, Parida SK, van der Spuy G, Tromp G, Adetifa IMO, Donkor S, Howe R, Mayanja-Kizza H, Boom WH, Dockrell HM, Ottenhoff THM, Hatherill M, Aderem A, Hanekom WA, Scriba TJ, Kaufmann SHE, Zak DE, Walzl G, GC6-74 cohort study team, The ACS cohort study team. PMID: 29624071; PMCID: PMC6019933.

View in: PubMed Mentions: 112 Fields:
Cri Critical Care Pul Pulmonary Medicine
Bacillus Calmette-Guérin (BCG) Revaccination of Adults with Latent Mycobacterium tuberculosis Infection Induces Long-Lived BCG-Reactive NK Cell Responses. J Immunol. 2016 08 15; 197(4):1100-1110. Suliman S, Geldenhuys H, Johnson JL, Hughes JE, Smit E, Murphy M, Toefy A, Lerumo L, Hopley C, Pienaar B, Chheng P, Nemes E, Hoft DF, Hanekom WA, Boom WH, Hatherill M, Scriba TJ. PMID: 27412415; PMCID: PMC4976036.

View in: PubMed Mentions: 80 Fields:
All Allergy and Immunology
Translation:Humans Cells CTClinical Trials