Joel Ernst, MD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address2540 23rd Street, #3805
San Francisco CA 94110
ORCID ORCID Icon0000-0001-9951-6207 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Nebraska, Omaha, NEM.D.05/1978Medicine
    University of California, San Francisco, San Francisco CA06/1981Internal Medicine
    University of California, San Francisco, San Francisco, CA06/1982Infectious Diseases
    University of California, San Francisco, San Francisco, CA06/1984Hematology and Oncology
    University of California, San Francisco, San Francisco, CA06/1986Leukocyte cell biology
    University of California, San Francisco, CA2018Diversity, Equity, and Inclusion Champion Training
    Collapse Awards and Honors
    Association of American Physicians2009Elected Member
    University of Washington2009Kirby Lecturer
    Aeras Global TB Vaccine Foundation2009Thaler Lecturer
    American Academy of Microbiologists2010Elected Fellow
    Linköping University, Sweden2013Honorary Doctorate (M.D., honoris causa)
    New York University School of Medicine2015Dean's Honors Lecturer
    University of Nebraska2016McFadden Memorial Lecturer

    Collapse Overview 
    Collapse Overview
    The goal of my research is to provide the mechanistic basis for development of effective vaccines against tuberculosis.
    Collapse Global Health Equity

    Collapse Research 
    Collapse Research Activities and Funding
    Live Imaging of Immunity to M. tuberculosis
    NIH R21AI156407Jan 6, 2021 - Dec 31, 2022
    Role: Principal Investigator
    Host genetic diversity, T cell responses, and outcomes of TB
    NIH R21AI152564Sep 1, 2020 - Aug 31, 2022
    Role: Principal Investigator
    Host genetic diversity, mononuclear phagocytes, and outcomes of TB
    NIH R21AI152563Jun 16, 2020 - May 30, 2022
    Role: Principal Investigator
    Childhood ?Omics? and Mycobacterium tuberculosis-derived BiOsignatures (COMBO) for TB diagnosis in high HIV prevalence settings
    NIH R01AI152161Apr 22, 2020 - Mar 31, 2025
    Role: Co-Principal Investigator
    A novel approach for deep phenotyping the CD4 T cell response to Mycobacterium Tuberculosis
    NIH R21AI149311Feb 18, 2020 - Jan 31, 2022
    Role: Co-Principal Investigator
    Antigen export in M. tuberculosis evasion of CD4 T cells
    NIH R01AI124471Jul 20, 2016 - Jun 30, 2021
    Role: Principal Investigator
    Role of antigen-specific T cell responses in the control of TB
    NIH U19AI111211Aug 11, 2014 - Jul 31, 2021
    Role: Co-Principal Investigator
    Epitope-specific T cell activation to complement TB immunity and vaccine efficacy
    NIH R56AI105180Jul 15, 2014 - Jun 30, 2016
    Role: Principal Investigator
    Training Program in Immunology and Inflammation
    NIH T32AI100853Jul 1, 2012 - Jun 30, 2022
    Role: Co-Principal Investigator
    Mycobacterium tuberculosis antigen diversity
    NIH R01AI090928Jun 15, 2010 - May 31, 2016
    Role: Principal Investigator
    Mycobacterium tuberculosis evasion of CD4+ T cells in vivo
    NIH R01AI084041Jan 15, 2010 - Dec 31, 2015
    Role: Principal Investigator
    Mycobacterium tuberculosis evasion of CD4+ T cells in vivo
    NIH R56AI084041Jul 22, 2009 - Dec 31, 2009
    Role: Principal Investigator
    Type I Interferons in Immunity to Tuberculosis
    NIH R01AI059667Feb 15, 2004 - Jan 31, 2010
    Role: Principal Investigator
    Tuberculosis Immunity: Essential Host Genes
    NIH R03AI053074Sep 15, 2002 - Aug 31, 2005
    Role: Principal Investigator
    Cellular and Bacterial Dynamics in Tuberculosis
    NIH R01AI051242Dec 1, 2001 - Dec 31, 2020
    Role: Principal Investigator
    M. tuberculosis evasion of immune effector mechanisms
    NIH R01AI046097Jun 1, 2000 - May 31, 2010
    Role: Principal Investigator
    NIH R01HL056001Apr 25, 1996 - Mar 31, 2001
    Role: Principal Investigator
    NIH R01HL051992Sep 30, 1993 - Aug 31, 2003
    Role: Co-Principal Investigator
    NIH R29AI023697Jul 1, 1986 - Jun 30, 1991
    Role: Principal Investigator
    NIH R23AI023697Jul 1, 1986 - Jun 30, 1989
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Collaboration Interests

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL17 against M. tuberculosis antigen. bioRxiv. 2024 Mar 06. Ogongo P, Tran A, Marzan F, Gingrich D, Krone M, Aweeka F, Lindestam Arlehamn CS, Martin JN, Deeks SG, Hunt PW, Ernst JD. PMID: 36711855; PMCID: PMC9881994.
      View in: PubMed   Mentions:
    2. Rare Variable M. tuberculosis Antigens induce predominant Th17 responses in human infection. bioRxiv. 2024 Mar 06. Ogongo P, Wassie L, Tran A, Columbus D, Sharling L, Ouma G, Ouma SG, Bobosha K, Lindestam Arlehamn CS, Gandhi NR, Auld SC, Rengarajan J, Day CL, Altman JD, Blumberg HM, Ernst JD, TBRU ASTRa Study Group. PMID: 38496518; PMCID: PMC10942433.
      View in: PubMed   Mentions:
    3. A teenage girl with altered mental status and paraparesis. J Clin Tuberc Other Mycobact Dis. 2024 May; 35:100425. Miyakawa R, Louie J, Keh C, Chen L, Javid B, Ernst JD, Goswami N, Chow FC. PMID: 38468819; PMCID: PMC10926304.
      View in: PubMed   Mentions:
    4. selSeq: A method for the enrichment of non-polyadenylated RNAs including enhancer and long non-coding RNAs for sequencing. PLoS One. 2023; 18(11):e0289442. Limberis JD, Nalyvayko A, Ernst JD, Metcalfe JZ. PMID: 38015898; PMCID: PMC10684010.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    5. A simple, single-tube overlapping amplicon-targeted Illumina sequencing assay. PLoS One. 2023; 18(9):e0288687. Limberis JD, Nalyvayko A, Ernst JD, Metcalfe JZ. PMID: 37708184; PMCID: PMC10501585.
      View in: PubMed   Mentions:    Fields:    
    6. Mycobacterium tuberculosis resides in lysosome-poor monocyte-derived lung cells during chronic infection. Res Sq. 2023 Jun 15. Zheng W, Chang IC, Limberis J, Budzik J, Zha BS, Howard Z, Chen L, Ernst J. PMID: 37398178; PMCID: PMC10312915.
      View in: PubMed   Mentions:
    7. Mycobacterium tuberculosis resides in lysosome-poor monocyte-derived lung cells during chronic infection. bioRxiv. 2023 May 28. Zheng W, Chang IC, Limberis J, Budzik JM, Zha BS, Howard Z, Chen L, Ernst JD. PMID: 36711606; PMCID: PMC9882350.
      View in: PubMed   Mentions: 1  
    8. Back-to-Africa introductions of Mycobacterium tuberculosis as the main cause of tuberculosis in Dar es Salaam, Tanzania. PLoS Pathog. 2023 04; 19(4):e1010893. Zwyer M, Rutaihwa LK, Windels E, Hella J, Menardo F, Sasamalo M, Sommer G, Schmülling L, Borrell S, Reinhard M, Dötsch A, Hiza H, Stritt C, Sikalengo G, Fenner L, De Jong BC, Kato-Maeda M, Jugheli L, Ernst JD, Niemann S, Jeljeli L, Ballif M, Egger M, Rakotosamimanana N, Yeboah-Manu D, Asare P, Malla B, Dou HY, Zetola N, Wilkinson RJ, Cox H, Carter EJ, Gnokoro J, Yotebieng M, Gotuzzo E, Abimiku A, Avihingsanon A, Xu ZM, Fellay J, Portevin D, Reither K, Stadler T, Gagneux S, Brites D. PMID: 37014917; PMCID: PMC10104295.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    9. Spatial mapping reveals granuloma diversity and histopathological superstructure in human tuberculosis. J Exp Med. 2023 06 05; 220(6). Sawyer AJ, Patrick E, Edwards J, Wilmott JS, Fielder T, Yang Q, Barber DL, Ernst JD, Britton WJ, Palendira U, Chen X, Feng CG. PMID: 36920308; PMCID: PMC10035589.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    10. Circularization of rv0678 for Genotypic Bedaquiline Resistance Testing of Mycobacterium tuberculosis. Microbiol Spectr. 2023 Mar 06; e0412722. Limberis JD, Nalyvayko A, Ernst JD, Metcalfe JZ. PMID: 36877083; PMCID: PMC10100719.
      View in: PubMed   Mentions: 1     Fields:    
    11. Finding antigens for TB vaccines: the good, the bad and the useless. Nat Med. 2023 01; 29(1):35-36. Ogongo P, Ernst JD. PMID: 36604539; PMCID: PMC9877171.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    12. High-resolution imaging of protein secretion at the single-cell level using plasmon-enhanced FluoroDOT assay. Cell Rep Methods. 2022 08 22; 2(8):100267. Seth A, Mittal E, Luan J, Kolla S, Mazer MB, Joshi H, Gupta R, Rathi P, Wang Z, Morrissey JJ, Ernst JD, Portal-Celhay C, Morley SC, Philips JA, Singamaneni S. PMID: 36046626; PMCID: PMC9421537.
      View in: PubMed   Mentions: 5  Translation:HumansCells
    13. Bacterial Strain-Dependent Dissociation of Cell Recruitment and Cell-to-Cell Spread in Early M. tuberculosis Infection. mBio. 2022 06 28; 13(3):e0133222. Zha BS, Desvignes L, Fergus TJ, Cornelius A, Cheng TY, Moody DB, Ernst JD. PMID: 35695454; PMCID: PMC9239178.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    14. Repeated Plasmodium falciparum infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire. Sci Transl Med. 2021 12; 13(622):eabe7430. von Borstel A, Chevour P, Arsovski D, Krol JMM, Howson LJ, Berry AA, Day CL, Ogongo P, Ernst JD, Nomicos EYH, Boddey JA, Giles EM, Rossjohn J, Traore B, Lyke KE, Williamson KC, Crompton PD, Davey MS. PMID: 34851691; PMCID: PMC9291638.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    15. A Framework to Identify Antigen-Expanded T Cell Receptor Clusters Within Complex Repertoires. Front Immunol. 2021; 12:735584. Ceglia V, Kelley EJ, Boyle AS, Zurawski S, Mead HL, Harms CE, Blanck JP, Flamar AL, Kirschman JH, Ogongo P, Ernst JD, Levy Y, Zurawski G, Altin JA. PMID: 34917073; PMCID: PMC8670329.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    16. A defective viral genome strategy elicits broad protective immunity against respiratory viruses. Cell. 2021 12 09; 184(25):6037-6051.e14. Xiao Y, Lidsky PV, Shirogane Y, Aviner R, Wu CT, Li W, Zheng W, Talbot D, Catching A, Doitsh G, Su W, Gekko CE, Nayak A, Ernst JD, Brodsky L, Brodsky E, Rousseau E, Capponi S, Bianco S, Nakamura R, Jackson PK, Frydman J, Andino R. PMID: 34852237; PMCID: PMC8598942.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    17. Toward Comprehensive Plasma Proteomics by Orthogonal Protease Digestion. J Proteome Res. 2021 08 06; 20(8):4031-4040. Fossati A, Richards AL, Chen KH, Jaganath D, Cattamanchi A, Ernst JD, Swaney DL. PMID: 34319755; PMCID: PMC8442619.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    18. Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease. Nat Immunol. 2021 06; 22(6):781-793. Nathan A, Beynor JI, Baglaenko Y, Suliman S, Ishigaki K, Asgari S, Huang CC, Luo Y, Zhang Z, Lopez K, Lindestam Arlehamn CS, Ernst JD, Jimenez J, Calderón RI, Lecca L, Van Rhijn I, Moody DB, Murray MB, Raychaudhuri S. PMID: 34031617; PMCID: PMC8162307.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    19. Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins. Cell Rep. 2021 05 11; 35(6):109105. Hiatt J, Cavero DA, McGregor MJ, Zheng W, Budzik JM, Roth TL, Haas KM, Wu D, Rathore U, Meyer-Franke A, Bouzidi MS, Shifrut E, Lee Y, Kumar VE, Dang EV, Gordon DE, Wojcechowskyj JA, Hultquist JF, Fontaine KA, Pillai SK, Cox JS, Ernst JD, Krogan NJ, Marson A. PMID: 33979618; PMCID: PMC8188731.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    20. Schistosoma mansoni Infection Is Associated With a Higher Probability of Tuberculosis Disease in HIV-Infected Adults in Kenya. J Acquir Immune Defic Syndr. 2021 02 01; 86(2):157-163. McLaughlin TA, Nizam A, Hayara FO, Ouma GS, Campbell A, Khayumbi J, Ongalo J, Ouma SG, Shah NS, Altman JD, Kaushal D, Rengarajan J, Ernst JD, Blumberg HM, Waller LA, Gandhi NR, Day CL, Benkeser D. PMID: 33074856; PMCID: PMC8284023.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    21. Evaluation of SARS-CoV-2 serology assays reveals a range of test performance. Nat Biotechnol. 2020 10; 38(10):1174-1183. Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, Balcerek J, Bylsma SA, Lyons AM, Li S, Wong AW, Gillis-Buck EM, Steinhart ZB, Lee Y, Apathy R, Lipke MJ, Smith JA, Zheng T, Boothby IC, Isaza E, Chan J, Acenas DD, Lee J, Macrae TA, Kyaw TS, Wu D, Ng DL, Gu W, York VA, Eskandarian HA, Callaway PC, Warrier L, Moreno ME, Levan J, Torres L, Farrington LA, Loudermilk RP, Koshal K, Zorn KC, Garcia-Beltran WF, Yang D, Astudillo MG, Bernstein BE, Gelfand JA, Ryan ET, Charles RC, Iafrate AJ, Lennerz JK, Miller S, Chiu CY, Stramer SL, Wilson MR, Manglik A, Ye CJ, Krogan NJ, Anderson MS, Cyster JG, Ernst JD, Wu AHB, Lynch KL, Bern C, Hsu PD, Marson A. PMID: 32855547; PMCID: PMC7740072.
      View in: PubMed   Mentions: 151     Fields:    Translation:HumansCellsPHPublic Health
    22. Tryptophan catabolism reflects disease activity in human tuberculosis. JCI Insight. 2020 05 21; 5(10). Collins JM, Siddiqa A, Jones DP, Liu K, Kempker RR, Nizam A, Shah NS, Ismail N, Ouma SG, Tukvadze N, Li S, Day CL, Rengarajan J, Brust JC, Gandhi NR, Ernst JD, Blumberg HM, Ziegler TR. PMID: 32369456; PMCID: PMC7259525.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCellsCTClinical Trials
    23. Test performance evaluation of SARS-CoV-2 serological assays. medRxiv. 2020 May 17. Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, Balcerek J, Bylsma SA, Lyons AM, Li S, Wong AW, Gillis-Buck EM, Steinhart ZB, Lee Y, Apathy R, Lipke MJ, Smith JA, Zheng T, Boothby IC, Isaza E, Chan J, Acenas DD, Lee J, Macrae TA, Kyaw TS, Wu D, Ng DL, Gu W, York VA, Eskandarian HA, Callaway PC, Warrier L, Moreno ME, Levan J, Torres L, Farrington LA, Loudermilk R, Koshal K, Zorn KC, Garcia-Beltran WF, Yang D, Astudillo MG, Bernstein BE, Gelfand JA, Ryan ET, Charles RC, Iafrate AJ, Lennerz JK, Miller S, Chiu CY, Stramer SL, Wilson MR, Manglik A, Ye CJ, Krogan NJ, Anderson MS, Cyster JG, Ernst JD, Wu AHB, Lynch KL, Bern C, Hsu PD, Marson A. PMID: 32511497; PMCID: PMC7273265.
      View in: PubMed   Mentions: 18  
    24. Anti-ganglioside antibodies in patients with Zika virus infection-associated Guillain-Barré Syndrome in Brazil. PLoS Negl Trop Dis. 2019 09; 13(9):e0007695. Rivera-Correa J, de Siqueira IC, Mota S, do Rosário MS, Pereira de Jesus PA, Alcantara LCJ, Ernst JD, Rodriguez A. PMID: 31527907; PMCID: PMC6764688.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    25. Dynamics of Mycobacterium tuberculosis Ag85B Revealed by a Sensitive Enzyme-Linked Immunosorbent Assay. mBio. 2019 04 23; 10(2). Ernst JD, Cornelius A, Bolz M. PMID: 31015327; PMCID: PMC6479003.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    26. Mononuclear cell dynamics in M. tuberculosis infection provide opportunities for therapeutic intervention. PLoS Pathog. 2018 10; 14(10):e1007154. Norris BA, Ernst JD. PMID: 30365557; PMCID: PMC6221360.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    27. Limited Antimycobacterial Efficacy of Epitope Peptide Administration Despite Enhanced Antigen-Specific CD4 T-Cell Activation. J Infect Dis. 2018 10 05; 218(10):1653-1662. Ernst JD, Cornelius A, Desvignes L, Tavs J, Norris BA. PMID: 29548008; PMCID: PMC6173573.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    28. Mechanisms of M. tuberculosis Immune Evasion as Challenges to TB Vaccine Design. Cell Host Microbe. 2018 07 11; 24(1):34-42. Ernst JD. PMID: 30001523; PMCID: PMC6482466.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    29. Float Like Bacilli, STING Like a B: Type I Interferons in Tuberculosis. Am J Respir Crit Care Med. 2018 03 15; 197(6):706-707. Ernst JD. PMID: 29262261; PMCID: PMC5855075.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    30. A High Throughput Whole Blood Assay for Analysis of Multiple Antigen-Specific T Cell Responses in Human Mycobacterium tuberculosis Infection. J Immunol. 2018 04 15; 200(8):3008-3019. Whatney WE, Gandhi NR, Lindestam Arlehamn CS, Nizam A, Wu H, Quezada MJ, Campbell A, Allana S, Kabongo MM, Khayumbi J, Muchiri B, Ongalo J, Tonui J, Sasser LE, Fergus TJ, Ouma GS, Ouma SG, Beck AA, Mulligan MJ, Oladele A, Kaushal D, Cain KP, Waller L, Blumberg HM, Altman JD, Ernst JD, Rengarajan J, Day CL, TBRU-ASTRa Study Group. PMID: 29540577; PMCID: PMC5995335.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    31. Fishing for Answers in Human Mycobacterial Infections. Immunity. 2017 09 19; 47(3):395-397. Bolz M, Ernst JD. PMID: 28930653; PMCID: PMC6481165.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    32. "The Impact of Mycobacterium tuberculosis Immune Evasion on Protective Immunity: Implications for TB Vaccine Design" - Meeting report. Vaccine. 2017 06 14; 35(27):3433-3440. Boggiano C, Eichelberg K, Ramachandra L, Shea J, Ramakrishnan L, Behar S, Ernst JD, Porcelli SA, Maeurer M, Kornfeld H. PMID: 28476627; PMCID: PMC5718043.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    33. Sequence-based HLA-A, B, C, DP, DQ, and DR typing of 100 Luo infants from the Boro area of Nyanza Province, Kenya. Hum Immunol. 2017 Apr; 78(4):325-326. Arlehamn CS, Copin R, Leary S, Mack SJ, Phillips E, Mallal S, Sette A, Blatner G, Siefers H, Ernst JD, TBRU-ASTRa Study Team. PMID: 28315719; PMCID: PMC5519768.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    34. Antigenic Variation and Immune Escape in the MTBC. Adv Exp Med Biol. 2017; 1019:171-190. Ernst JD. PMID: 29116635; PMCID: PMC5718154.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    35. Within Host Evolution Selects for a Dominant Genotype of Mycobacterium tuberculosis while T Cells Increase Pathogen Genetic Diversity. PLoS Pathog. 2016 Dec; 12(12):e1006111. Copin R, Wang X, Louie E, Escuyer V, Coscolla M, Gagneux S, Palmer GH, Ernst JD. PMID: 27973588; PMCID: PMC5189959.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    36. Mycobacterium tuberculosis EsxH inhibits ESCRT-dependent CD4+ T-cell activation. Nat Microbiol. 2016 Dec 05; 2:16232. Portal-Celhay C, Tufariello JM, Srivastava S, Zahra A, Klevorn T, Grace PS, Mehra A, Park HS, Ernst JD, Jacobs WR, Philips JA. PMID: 27918526; PMCID: PMC5453184.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    37. Type I Interferon is Pathogenic During Chronic Mycobacterium africanum Infection. J Infect Dis. 2016 Dec 15; 214(12):1893-1896. Wiens KE, Ernst JD. PMID: 27803172; PMCID: PMC5142099.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    38. The Challenge of Latent TB Infection. JAMA. 2016 Sep 06; 316(9):931-3. Blumberg HM, Ernst JD. PMID: 27599327; PMCID: PMC5319563.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    39. The Mechanism for Type I Interferon Induction by Mycobacterium tuberculosis is Bacterial Strain-Dependent. PLoS Pathog. 2016 08; 12(8):e1005809. Wiens KE, Ernst JD. PMID: 27500737; PMCID: PMC4976988.
      View in: PubMed   Mentions: 90     Fields:    Translation:AnimalsCells
    40. A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans. PLoS Pathog. 2016 07; 12(7):e1005760. Lindestam Arlehamn CS, McKinney DM, Carpenter C, Paul S, Rozot V, Makgotlho E, Gregg Y, van Rooyen M, Ernst JD, Hatherill M, Hanekom WA, Peters B, Scriba TJ, Sette A. PMID: 27409590; PMCID: PMC4943605.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    41. Antigen Export Reduces Antigen Presentation and Limits T Cell Control of M. tuberculosis. Cell Host Microbe. 2016 Jan 13; 19(1):44-54. Srivastava S, Grace PS, Ernst JD. PMID: 26764596; PMCID: PMC4715867.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    42. Correction: LprG-Mediated Surface Expression of Lipoarabinomannan Is Essential for Virulence of Mycobacterium tuberculosis. PLoS Pathog. 2015 Dec; 11(12):e1005336. Gaur RL, Ren K, Blumenthal A, Bhamidi S, Gibbs S, Jackson M, Zare RN, Ehrt S, Ernst JD, Banaei N. PMID: 26650245; PMCID: PMC4674111.
      View in: PubMed   Mentions:    Fields:    
    43. Suboptimal Antigen Presentation Contributes to Virulence of Mycobacterium tuberculosis In Vivo. J Immunol. 2016 Jan 01; 196(1):357-64. Grace PS, Ernst JD. PMID: 26573837; PMCID: PMC4684992.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    44. M. tuberculosis T Cell Epitope Analysis Reveals Paucity of Antigenic Variation and Identifies Rare Variable TB Antigens. Cell Host Microbe. 2015 Nov 11; 18(5):538-48. Coscolla M, Copin R, Sutherland J, Gehre F, de Jong B, Owolabi O, Mbayo G, Giardina F, Ernst JD, Gagneux S. PMID: 26607161; PMCID: PMC4758912.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansCells
    45. STIM1 controls T cell-mediated immune regulation and inflammation in chronic infection. J Clin Invest. 2015 Jun; 125(6):2347-62. Desvignes L, Weidinger C, Shaw P, Vaeth M, Ribierre T, Liu M, Fergus T, Kozhaya L, McVoy L, Unutmaz D, Ernst JD, Feske S. PMID: 25938788; PMCID: PMC4518689.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    46. In vivo biosynthesis of terpene nucleosides provides unique chemical markers of Mycobacterium tuberculosis infection. Chem Biol. 2015 Apr 23; 22(4):516-526. Young DC, Layre E, Pan SJ, Tapley A, Adamson J, Seshadri C, Wu Z, Buter J, Minnaard AJ, Coscolla M, Gagneux S, Copin R, Ernst JD, Bishai WR, Snider BB, Moody DB. PMID: 25910243; PMCID: PMC4432472.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    47. Beyond macrophages: the diversity of mononuclear cells in tuberculosis. Immunol Rev. 2014 Nov; 262(1):179-92. Srivastava S, Ernst JD, Desvignes L. PMID: 25319335; PMCID: PMC4203409.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    48. LprG-mediated surface expression of lipoarabinomannan is essential for virulence of Mycobacterium tuberculosis. PLoS Pathog. 2014 Sep; 10(9):e1004376. Gaur RL, Ren K, Blumenthal A, Bhamidi S, González-Nilo FD, Gibbs S, Jackson M, Zare RN, Ehrt S, Ernst JD, Banaei N. PMID: 25232742; PMCID: PMC4169494.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    49. Impact of in vitro evolution on antigenic diversity of Mycobacterium bovis bacillus Calmette-Guerin (BCG). Vaccine. 2014 Oct 14; 32(45):5998-6004. Copin R, Coscollá M, Efstathiadis E, Gagneux S, Ernst JD. PMID: 25211768; PMCID: PMC4539939.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    50. Cell-to-cell transfer of M. tuberculosis antigens optimizes CD4 T cell priming. Cell Host Microbe. 2014 Jun 11; 15(6):741-52. Srivastava S, Ernst JD. PMID: 24922576; PMCID: PMC4098643.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    51. Sequence diversity in the pe_pgrs genes of Mycobacterium tuberculosis is independent of human T cell recognition. mBio. 2014 Jan 14; 5(1):e00960-13. Copin R, Coscollá M, Seiffert SN, Bothamley G, Sutherland J, Mbayo G, Gagneux S, Ernst JD. PMID: 24425732; PMCID: PMC3903279.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    52. Equivalent T cell epitope promiscuity in ecologically diverse human pathogens. PLoS One. 2013; 8(8):e73124. Wiens KE, Swaminathan H, Copin R, Lun DS, Ernst JD. PMID: 23951341; PMCID: PMC3739752.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    53. Cutting edge: Direct recognition of infected cells by CD4 T cells is required for control of intracellular Mycobacterium tuberculosis in vivo. J Immunol. 2013 Aug 01; 191(3):1016-20. Srivastava S, Ernst JD. PMID: 23817429; PMCID: PMC3725655.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    54. Taking sides: interferons in leprosy. Cell Host Microbe. 2013 Apr 17; 13(4):377-8. Desvignes LP, Ernst JD. PMID: 23601100; PMCID: PMC3671607.
      View in: PubMed   Mentions: 2     Fields:    
    55. Variation of Mycobacterium tuberculosis antigen-specific IFN-γ and IL-17 responses in healthy tuberculin skin test (TST)-positive human subjects. PLoS One. 2012; 7(8):e42716. Fan L, Xiao HP, Hu ZY, Ernst JD. PMID: 22880090; PMCID: PMC3412824.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    56. CD4+ T cell-dependent IFN-γ production by CD8+ effector T cells in Mycobacterium tuberculosis infection. J Immunol. 2012 Sep 01; 189(5):2530-6. Bold TD, Ernst JD. PMID: 22837486; PMCID: PMC3424308.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    57. The immunological life cycle of tuberculosis. Nat Rev Immunol. 2012 Jul 13; 12(8):581-91. Ernst JD. PMID: 22790178.
      View in: PubMed   Mentions: 263     Fields:    Translation:HumansAnimalsCells
    58. Meeting report: The International Conference on Human Immunity to Tuberculosis. Tuberculosis (Edinb). 2012 Sep; 92(5):440-4. Ernst JD, Hanekom W, Hawn T, Kampmann B, Rengarajan J. PMID: 22658910.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    59. Dynamic roles of type I and type II IFNs in early infection with Mycobacterium tuberculosis. J Immunol. 2012 Jun 15; 188(12):6205-15. Desvignes L, Wolf AJ, Ernst JD. PMID: 22566567; PMCID: PMC3370955.
      View in: PubMed   Mentions: 90     Fields:    Translation:AnimalsCells
    60. Impaired fitness of Mycobacterium africanum despite secretion of ESAT-6. J Infect Dis. 2012 Mar 15; 205(6):984-90. Bold TD, Davis DC, Penberthy KK, Cox LM, Ernst JD, de Jong BC. PMID: 22301632; PMCID: PMC3282571.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    61. Mycobacterium tuberculosis inhibits neutrophil apoptosis, leading to delayed activation of naive CD4 T cells. Cell Host Microbe. 2012 Jan 19; 11(1):81-90. Blomgran R, Desvignes L, Briken V, Ernst JD. PMID: 22264515; PMCID: PMC3266554.
      View in: PubMed   Mentions: 91     Fields:    Translation:Cells
    62. Tuberculosis pathogenesis and immunity. Annu Rev Pathol. 2012; 7:353-84. Philips JA, Ernst JD. PMID: 22054143.
      View in: PubMed   Mentions: 164     Fields:    Translation:HumansCells
    63. Suboptimal activation of antigen-specific CD4+ effector cells enables persistence of M. tuberculosis in vivo. PLoS Pathog. 2011 May; 7(5):e1002063. Bold TD, Banaei N, Wolf AJ, Ernst JD. PMID: 21637811; PMCID: PMC3102708.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    64. Lung neutrophils facilitate activation of naive antigen-specific CD4+ T cells during Mycobacterium tuberculosis infection. J Immunol. 2011 Jun 15; 186(12):7110-9. Blomgran R, Ernst JD. PMID: 21555529; PMCID: PMC3376160.
      View in: PubMed   Mentions: 121     Fields:    Translation:AnimalsCells
    65. Directly observing therapy: a new view of drug tolerance in tuberculosis. Cell. 2011 Apr 01; 145(1):13-4. Philips JA, Ernst JD. PMID: 21458661.
      View in: PubMed   Mentions: 1     Fields:    
    66. HIV and tuberculosis: a deadly human syndemic. Clin Microbiol Rev. 2011 Apr; 24(2):351-76. Kwan CK, Ernst JD. PMID: 21482729; PMCID: PMC3122491.
      View in: PubMed   Mentions: 303     Fields:    Translation:HumansPHPublic Health
    67. Initiation and regulation of T-cell responses in tuberculosis. Mucosal Immunol. 2011 May; 4(3):288-93. Urdahl KB, Shafiani S, Ernst JD. PMID: 21451503; PMCID: PMC3206635.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansAnimalsCells
    68. Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved. Nat Genet. 2010 Jun; 42(6):498-503. Comas I, Chakravartti J, Small PM, Galagan J, Niemann S, Kremer K, Ernst JD, Gagneux S. PMID: 20495566; PMCID: PMC2883744.
      View in: PubMed   Mentions: 361     Fields:    Translation:HumansCells
    69. Interferon-gamma-responsive nonhematopoietic cells regulate the immune response to Mycobacterium tuberculosis. Immunity. 2009 Dec 18; 31(6):974-85. Desvignes L, Ernst JD. PMID: 20064452; PMCID: PMC2807991.
      View in: PubMed   Mentions: 132     Fields:    Translation:AnimalsCells
    70. Ectopic activation of Mycobacterium tuberculosis-specific CD4+ T cells in lungs of CCR7-/- mice. J Immunol. 2010 Jan 15; 184(2):895-901. Olmos S, Stukes S, Ernst JD. PMID: 20007536; PMCID: PMC2879893.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    71. TLR2-dependent inhibition of macrophage responses to IFN-gamma is mediated by distinct, gene-specific mechanisms. PLoS One. 2009 Jul 24; 4(7):e6329. Benson SA, Ernst JD. PMID: 19629181; PMCID: PMC2710511.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    72. Lipoprotein processing is essential for resistance of Mycobacterium tuberculosis to malachite green. Antimicrob Agents Chemother. 2009 Sep; 53(9):3799-802. Banaei N, Kincaid EZ, Lin SY, Desmond E, Jacobs WR, Ernst JD. PMID: 19596883; PMCID: PMC2737861.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    73. Anti-TNF immunotherapy and tuberculosis reactivation: another mechanism revealed. J Clin Invest. 2009 May; 119(5):1079-82. Miller EA, Ernst JD. PMID: 19422095; PMCID: PMC2673853.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    74. RP105 facilitates macrophage activation by Mycobacterium tuberculosis lipoproteins. Cell Host Microbe. 2009 Jan 22; 5(1):35-46. Blumenthal A, Kobayashi T, Pierini LM, Banaei N, Ernst JD, Miyake K, Ehrt S. PMID: 19154986; PMCID: PMC2742161.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    75. Who benefits from granulomas, mycobacteria or host? Cell. 2009 Jan 09; 136(1):17-9. Bold TD, Ernst JD. PMID: 19135882; PMCID: PMC4214211.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    76. Illuminating the black box of TNF action in tuberculous granulomas. Immunity. 2008 Aug 15; 29(2):175-7. Miller EA, Ernst JD. PMID: 18701080.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    77. CO-opting the host HO-1 pathway in tuberculosis and malaria. Cell Host Microbe. 2008 May 15; 3(5):277-9. Sinnis P, Ernst JD. PMID: 18474353.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    78. Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs. J Exp Med. 2008 Jan 21; 205(1):105-15. Wolf AJ, Desvignes L, Linas B, Banaiee N, Tamura T, Takatsu K, Ernst JD. PMID: 18158321; PMCID: PMC2234384.
      View in: PubMed   Mentions: 284     Fields:    Translation:AnimalsCells
    79. Meeting Report: NIH Workshop on the Tuberculosis Immune Epitope Database. Tuberculosis (Edinb). 2008 Jul; 88(4):366-70. Ernst JD, Lewinsohn DM, Behar S, Blythe M, Schlesinger LS, Kornfeld H, Sette A. PMID: 18068490; PMCID: PMC2504685.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    80. An analysis of the epitope knowledge related to Mycobacteria. Immunome Res. 2007 Dec 14; 3:10. Blythe MJ, Zhang Q, Vaughan K, de Castro R, Salimi N, Bui HH, Lewinsohn DM, Ernst JD, Peters B, Sette A. PMID: 18081934; PMCID: PMC2228276.
      View in: PubMed   Mentions: 40  
    81. Codominance of TLR2-dependent and TLR2-independent modulation of MHC class II in Mycobacterium tuberculosis infection in vivo. J Immunol. 2007 Sep 01; 179(5):3187-95. Kincaid EZ, Wolf AJ, Desvignes L, Mahapatra S, Crick DC, Brennan PJ, Pavelka MS, Ernst JD. PMID: 17709534.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    82. Mycobacterium tuberculosis infects dendritic cells with high frequency and impairs their function in vivo. J Immunol. 2007 Aug 15; 179(4):2509-19. Wolf AJ, Linas B, Trevejo-Nuñez GJ, Kincaid E, Tamura T, Takatsu K, Ernst JD. PMID: 17675513.
      View in: PubMed   Mentions: 272     Fields:    Translation:AnimalsCells
    83. Genomics and the evolution, pathogenesis, and diagnosis of tuberculosis. J Clin Invest. 2007 Jul; 117(7):1738-45. Ernst JD, Trevejo-Nuñez G, Banaiee N. PMID: 17607348; PMCID: PMC1904327.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    84. LspA-independent action of globomycin on Mycobacterium tuberculosis. J Antimicrob Chemother. 2007 Aug; 60(2):414-6. Banaiee N, Jacobs WR, Ernst JD. PMID: 17579235.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    85. Regulation of Mycobacterium tuberculosis whiB3 in the mouse lung and macrophages. Infect Immun. 2006 Nov; 74(11):6449-57. Banaiee N, Jacobs WR, Ernst JD. PMID: 16923787; PMCID: PMC1695489.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    86. Potent inhibition of macrophage responses to IFN-gamma by live virulent Mycobacterium tuberculosis is independent of mature mycobacterial lipoproteins but dependent on TLR2. J Immunol. 2006 Mar 01; 176(5):3019-27. Banaiee N, Kincaid EZ, Buchwald U, Jacobs WR, Ernst JD. PMID: 16493060.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    87. GTP-dependent secretion from neutrophils is regulated by Cdk5. J Biol Chem. 2004 Dec 24; 279(52):53932-6. Rosales JL, Ernst JD, Hallows J, Lee KY. PMID: 15492003.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    88. CCR2-dependent trafficking of F4/80dim macrophages and CD11cdim/intermediate dendritic cells is crucial for T cell recruitment to lungs infected with Mycobacterium tuberculosis. J Immunol. 2004 Jun 15; 172(12):7647-53. Peters W, Cyster JG, Mack M, Schlöndorff D, Wolf AJ, Ernst JD, Charo IF. PMID: 15187146.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    89. Mycobacterium tuberculosis inhibits macrophage responses to IFN-gamma through myeloid differentiation factor 88-dependent and -independent mechanisms. J Immunol. 2004 May 15; 172(10):6272-80. Fortune SM, Solache A, Jaeger A, Hill PJ, Belisle JT, Bloom BR, Rubin EJ, Ernst JD. PMID: 15128816.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    90. Innate inhibition of adaptive immunity: Mycobacterium tuberculosis-induced IL-6 inhibits macrophage responses to IFN-gamma. J Immunol. 2003 Nov 01; 171(9):4750-7. Nagabhushanam V, Solache A, Ting LM, Escaron CJ, Zhang JY, Ernst JD. PMID: 14568951.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    91. Mycobacterium tuberculosis exerts gene-selective inhibition of transcriptional responses to IFN-gamma without inhibiting STAT1 function. J Immunol. 2003 Aug 15; 171(4):2042-9. Kincaid EZ, Ernst JD. PMID: 12902509.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    92. Mechanisms of cell recruitment in the immune response to Mycobacterium tuberculosis. Microbes Infect. 2003 Feb; 5(2):151-8. Peters W, Ernst JD. PMID: 12650773.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    93. Cholesterol esterification by host and parasite is essential for optimal proliferation of Toxoplasma gondii. J Biol Chem. 2001 Sep 14; 276(37):34434-40. Sonda S, Ting LM, Novak S, Kim K, Maher JJ, Farese RV, Ernst JD. PMID: 11457847.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    94. Chemokine receptor 2 serves an early and essential role in resistance to Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2001 Jul 03; 98(14):7958-63. Peters W, Scott HM, Chambers HF, Flynn JL, Charo IF, Ernst JD. PMID: 11438742; PMCID: PMC35450.
      View in: PubMed   Mentions: 122     Fields:    Translation:AnimalsCells
    95. Bacterial inhibition of phagocytosis. Cell Microbiol. 2000 Oct; 2(5):379-86. Ernst JD. PMID: 11207593.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    96. GTP-dependent permeabilized neutrophil secretion requires a freely diffusible cytosolic protein. J Cell Biochem. 2000 Sep 18; 80(1):37-45. Rosales JL, Ernst JD. PMID: 11029752.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    97. Phagocytosis of crocidolite asbestos induces oxidative stress, DNA damage, and apoptosis in mesothelial cells. Am J Respir Cell Mol Biol. 2000 Sep; 23(3):371-8. Liu W, Ernst JD, Broaddus VC. PMID: 10970829.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    98. Immune responses in tuberculosis. Curr Opin Immunol. 2000 Aug; 12(4):432-6. Flynn JL, Ernst JD. PMID: 10899019.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    99. Toward the development of antibacterial vaccines: report of a symposium and workshop. Organizing Committee. Clin Infect Dis. 1999 Nov; 29(5):1295-302. Ernst JD. PMID: 10524978.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    100. Mycobacterium tuberculosis inhibits IFN-gamma transcriptional responses without inhibiting activation of STAT1. J Immunol. 1999 Oct 01; 163(7):3898-906. Ting LM, Kim AC, Cattamanchi A, Ernst JD. PMID: 10490990.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansAnimalsCells
    101. Editorial response: variation in clinical and immune responses to bacille Calmette-Guérin--implications for an improved tuberculosis vaccine. Clin Infect Dis. 1999 Apr; 28(4):791-3. Ernst JD. PMID: 10825040.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    102. Preparation and characterization of an endogenously fluorescent annexin for detection of apoptotic cells. Anal Biochem. 1998 Jun 15; 260(1):18-23. Ernst JD, Yang L, Rosales JL, Broaddus VC. PMID: 9648647.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    103. Roles of calcium and annexins in phagocytosis and elimination of an attenuated strain of Mycobacterium tuberculosis in human neutrophils. Microb Pathog. 1998 May; 24(5):309-20. Majeed M, Perskvist N, Ernst JD, Orselius K, Stendahl O. PMID: 9600863.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    104. Macrophage receptors for Mycobacterium tuberculosis. Infect Immun. 1998 Apr; 66(4):1277-81. Ernst JD. PMID: 9529042; PMCID: PMC108049.
      View in: PubMed   Mentions: 132     Fields:    Translation:Cells
    105. Calcium-dependent neutrophil secretion: characterization and regulation by annexins. J Immunol. 1997 Dec 15; 159(12):6195-202. Rosales JL, Ernst JD. PMID: 9550422.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    106. Role of annexins in endocytosis of antigens in immature human dendritic cells. Immunology. 1997 Dec; 92(4):501-11. Larsson M, Majeed M, Ernst JD, Magnusson KE, Stendahl O, Forsum U. PMID: 9497492; PMCID: PMC1364156.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    107. Crocidolite asbestos induces apoptosis of pleural mesothelial cells: role of reactive oxygen species and poly(ADP-ribosyl) polymerase. Environ Health Perspect. 1997 Sep; 105 Suppl 5:1147-52. Broaddus VC, Yang L, Scavo LM, Ernst JD, Boylan AM. PMID: 9400715; PMCID: PMC1470163.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    108. Transfer of phagocytosed particles to the parasitophorous vacuole of Leishmania mexicana is a transient phenomenon preceding the acquisition of annexin I by the phagosome. J Cell Sci. 1997 Jan; 110 ( Pt 2):191-200. Collins HL, Schaible UE, Ernst JD, Russell DG. PMID: 9044049.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    109. Selective receptor blockade during phagocytosis does not alter the survival and growth of Mycobacterium tuberculosis in human macrophages. Am J Respir Cell Mol Biol. 1996 Dec; 15(6):760-70. Zimmerli S, Edwards S, Ernst JD. PMID: 8969271.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    110. Asbestos induces apoptosis of human and rabbit pleural mesothelial cells via reactive oxygen species. J Clin Invest. 1996 Nov 01; 98(9):2050-9. Broaddus VC, Yang L, Scavo LM, Ernst JD, Boylan AM. PMID: 8903324; PMCID: PMC507649.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    111. The (alpha2-->8)-linked polysialic acid capsule of group B Neisseria meningitidis modifies multiple steps during interaction with human macrophages. Infect Immun. 1996 Aug; 64(8):3210-7. Read RC, Zimmerli S, Broaddus C, Sanan DA, Stephens DS, Ernst JD. PMID: 8757855; PMCID: PMC174209.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    112. Detection of altered membrane phospholipid asymmetry in subpopulations of human red blood cells using fluorescently labeled annexin V. Blood. 1996 Feb 01; 87(3):1179-87. Kuypers FA, Lewis RA, Hua M, Schott MA, Discher D, Ernst JD, Lubin BH. PMID: 8562945.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    113. Phagosome-lysosome fusion is a calcium-independent event in macrophages. J Cell Biol. 1996 Jan; 132(1-2):49-61. Zimmerli S, Majeed M, Gustavsson M, Stendahl O, Sanan DA, Ernst JD. PMID: 8567729; PMCID: PMC2120694.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    114. Mobilization of annexin V during the uptake of DNP-albumin by human dendritic cells. APMIS. 1995 Dec; 103(12):855-61. Larsson M, Majeed M, Stendahl O, Magnusson KE, Ernst JD, Forsum U. PMID: 8562025.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    115. A fluorometric assay for the quantification of RNA in solution with nanogram sensitivity. Anal Biochem. 1995 Nov 20; 232(1):144-6. Schmidt DM, Ernst JD. PMID: 8600826.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    116. Calcium signalling initiated by CR1 (CD35) crosslinking is mediated by phagocyte Fc gamma receptors in cis. Biochem Biophys Res Commun. 1995 Apr 26; 209(3):1032-8. Ernst JD, Rosales JL, Zimmerli S. PMID: 7733955.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    117. Annexin expression in human dendritic cells. Adv Exp Med Biol. 1995; 378:191-3. Larsson M, Majeed M, Stendahl O, Magnusson KE, Ernst JD, Forsum U. PMID: 8526052.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    118. Selective translocation of annexins III, IV, and V during intracellular redistribution of Chlamydia trachomatis serovar L2 in HeLa and McCoy cells. Ann N Y Acad Sci. 1994 Aug 15; 730:326-8. Majeed M, Ernst JD, Magnusson KE, Kihlström E, Stendahl O. PMID: 8080201.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    119. Annexins possess functionally distinguishable Ca2+ and phospholipid binding domains. Biochem Biophys Res Commun. 1994 Apr 29; 200(2):867-76. Ernst JD, Mall A, Chew G. PMID: 8179621.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    120. Selective translocation of annexins during intracellular redistribution of Chlamydia trachomatis in HeLa and McCoy cells. Infect Immun. 1994 Jan; 62(1):126-34. Majeed M, Ernst JD, Magnusson KE, Kihlström E, Stendahl O. PMID: 8262618; PMCID: PMC186077.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    121. Epitope mapping of annexin I: antibodies that compete with phospholipids and calcium recognize amino acids 42-99. Biochem J. 1993 Jan 15; 289 ( Pt 2):539-42. Ernst JD. PMID: 7678738; PMCID: PMC1132201.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    122. Annexin III translocates to the periphagosomal region when neutrophils ingest opsonized yeast. J Immunol. 1991 May 01; 146(9):3110-4. Ernst JD. PMID: 1826705.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    123. Identification of a domain that mediates vesicle aggregation reveals functional diversity of annexin repeats. J Biol Chem. 1991 Apr 15; 266(11):6670-3. Ernst JD, Hoye E, Blackwood RA, Mok TL. PMID: 1707872.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    124. Purification and characterization of an abundant cytosolic protein from human neutrophils that promotes Ca2(+)-dependent aggregation of isolated specific granules. J Clin Invest. 1990 Apr; 85(4):1065-71. Ernst JD, Hoye E, Blackwood RA, Jaye D. PMID: 2138632; PMCID: PMC296536.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    125. Characterization of Ca2(+)-dependent phospholipid binding, vesicle aggregation and membrane fusion by annexins. Biochem J. 1990 Feb 15; 266(1):195-200. Blackwood RA, Ernst JD. PMID: 2138016; PMCID: PMC1131114.
      View in: PubMed   Mentions: 73     Fields:    Translation:Humans
    126. Use of a novel strategy for the preparation and characterization of an antipeptide antibody capable of recognizing members of the annexin family. Biochem Biophys Res Commun. 1989 Jun 30; 161(3):959-64. Ernst JD, Hoye E, Blackwood RA. PMID: 2742594.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    127. Synexin-like proteins from human polymorphonuclear leukocytes. Identification and characterization of granule-aggregating and membrane-fusing activities. J Biol Chem. 1987 Jun 05; 262(16):7850-8. Meers P, Ernst JD, Düzgünes N, Hong KL, Fedor J, Goldstein IM, Papahadjopoulos D. PMID: 2953727.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    128. Human polymorphonuclear leukocytes contain synexin, a calcium-binding protein that mediates membrane fusion. Trans Assoc Am Physicians. 1986; 99:58-66. Ernst JD, Meers P, Hong K, Duzgunes N, Papahadjopoulos D, Goldstein IM. PMID: 2955560.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    129. Complement (C5)-derived chemotactic activity accounts for accumulation of polymorphonuclear leukocytes in cerebrospinal fluid of rabbits with pneumococcal meningitis. Infect Immun. 1984 Oct; 46(1):81-6. Ernst JD, Hartiala KT, Goldstein IM, Sande MA. PMID: 6480117; PMCID: PMC261424.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    130. Correlation of in vitro time-kill curves and kinetics of bacterial killing in cerebrospinal fluid during ceftriaxone therapy of experimental Escherichia coli meningitis. Antimicrob Agents Chemother. 1983 Oct; 24(4):463-7. Decazes JM, Ernst JD, Sande MA. PMID: 6316841; PMCID: PMC185356.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    131. Experimental pneumococcal meningitis: role of leukocytes in pathogenesis. Infect Immun. 1983 Jul; 41(1):275-9. Ernst JD, Decazes JM, Sande MA. PMID: 6862627; PMCID: PMC264774.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    132. Combination antifungal chemotherapy for experimental disseminated candidiasis: lack of correlation between in vitro and in vivo observations with amphotericin B and rifampin. Rev Infect Dis. 1983 Jul-Aug; 5 Suppl 3:S626-30. Ernst JD, Rusnak M, Sande MA. PMID: 6356285.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    133. Inhibition of isolation of Escherichia coli in blood cultures by trimethoprim-sulfamethoxazole. J Infect Dis. 1983 May; 147(5):964-5. Hackbarth CJ, Ernst JD, Sande MA. PMID: 6341486.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    134. Antibiotic combinations in experimental infections in animals. Rev Infect Dis. 1982 Mar-Apr; 4(2):302-10. Ernst JD, Sande MA. PMID: 7051233.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
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