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    Anthony Luke, MD

    TitleProfessor
    SchoolUCSF School of Medicine
    DepartmentOrthopaedic Surgery
    Address1500 Owens Street
    San Fancisco CA 94158
    Phone415-885-3807

       Overview 
       Overview
      A major area of research I am working to develop is running injuries. I have also been expanding my clinical services to include RunSafe, a multi-disciplinary running injury prevention program, which we will enroll runners for injury surveillance and study of running injuries risk factors. The CHR for this study is being submitted and data should be able to be gathered this fall 2008. I was awarded a REAC grant to perform a MRI study on marathon runners, to better understand the effects of running on articular cartilage. This research was published in the American Journal of Sports Medicine in 2010. This new MRI technology can be applied in other treatments for osteoarthritis that I perform, so that athletes and patients can be studied further to identify cartilage protective interventions. A future will study marathon runners with a history of meniscal problems. The Mount Zion Health Fund has supported a scholarship fund to provide this valuable service to underprivileged participants in order to help improve health. Media coverage for the program include the SF Chronicle and San Francisco Magazine.
      My work as Director of the Human Performance Lab will also generate more research opportunities in the realms of biomechanics using an optical 10-camera system (VICON) and force plates. Exercise physiology testing with a metabolic cart (VO2 max testing) will also enable me to understand further on how to treat and train competitive athletes. I am supervising students who are conducting pilot studies in knee and ankle biomechanics, specifically in patients with patellar tendinopathy and ankle sprains.
      Over the past three years, I have been developing my research program to incorporate injury prevention and activity promotion, especially in the adolescent population. Through my work with the San Francisco Unified School District through the UCSF PlaySafe program, there are many opportunities to study a high school population for both clinical sports medicine problems and activity promotion issues. I have recently received a grant from the Canadian Academy of Sports Medicine that will allow use of a developed web-based survey to assess students in the United States, Canada and Switzerland, to better understand whether there are cultural issues affecting sports participation. At the present time, I have the heat injury prevention survey study which is approaching completion and will be submitted for publication. I will continue to build an infrastructure for research through the high school system in San Francisco, with hope to also study sports injury prevention. I am just completing a multi-center paper involving assessment of overscheduling concerns in youth sport.
      Musculoskeletal ultrasound is an imaging modality which I intend to use for research purposes. I am co-investigator on a large research industry funded grant to examine rotator cuff repair patients. I will be scanning patient pre-surgery and with regular post-op visits.


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       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Difiori JP, Benjamin HJ, Brenner J, Gregory A, Jayanthi N, Landry GL, Luke A. Overuse injuries and burnout in youth sports: a position statement from the american medical society for sports medicine. Clin J Sport Med. 2014 Jan; 24(1):3-20.
        View in: PubMed
      2. Thuillier DU, Souza RB, Wu S, Luke A, Li X, Feeley BT. T1? imaging demonstrates early changes in the lateral patella in patients with patellofemoral pain and maltracking. Am J Sports Med. 2013 Aug; 41(8):1813-8.
        View in: PubMed
      3. d'Hemecourt PA, Luke A. Sport-specific biomechanics of spinal injuries in aesthetic athletes (dancers, gymnasts, and figure skaters). Clin Sports Med. 2012 Jul; 31(3):397-408.
        View in: PubMed
      4. Souza RB, Fang C, Luke A, Wu S, Li X, Majumdar S. Relationship between knee kinetics during jumping tasks and knee articular cartilage MRI T1rho and T2 relaxation times. Clin Biomech (Bristol, Avon). 2012 May; 27(4):403-8.
        View in: PubMed
      5. Luke A, Lazaro RM, Bergeron MF, Keyser L, Benjamin H, Brenner J, d'Hemecourt P, Grady M, Philpott J, Smith A. Sports-related injuries in youth athletes: is overscheduling a risk factor? Clin J Sport Med. 2011 Jul; 21(4):307-14.
        View in: PubMed
      6. Behera SK, Pattnaik T, Luke A. Practical recommendations and perspectives on cardiac screening for healthy pediatric athletes. Curr Sports Med Rep. 2011 Mar-Apr; 10(2):90-8.
        View in: PubMed
      7. Stehling C, Luke A, Stahl R, Baum T, Joseph G, Pan J, Link TM. Meniscal T1rho and T2 measured with 3.0T MRI increases directly after running a marathon. Skeletal Radiol. 2011 Jun; 40(6):725-35.
        View in: PubMed
      8. Luke AC, Stehling C, Stahl R, Li X, Kay T, Takamoto S, Ma B, Majumdar S, Link T. High-field magnetic resonance imaging assessment of articular cartilage before and after marathon running: does long-distance running lead to cartilage damage? Am J Sports Med. 2010 Nov; 38(11):2273-80.
        View in: PubMed
      9. Philpott JF, Houghton K, Luke A. Physical activity recommendations for children with specific chronic health conditions: juvenile idiopathic arthritis, hemophilia, asthma, and cystic fibrosis. Clin J Sport Med. 2010 May; 20(3):167-72.
        View in: PubMed
      10. Philpott J, Wilson E, Luke A. The importance of exercise: know how to say 'go'. Pediatr Ann. 2010 Mar; 39(3):162-4, 166-8, 171.
        View in: PubMed
      11. Rauscher I, Stahl R, Cheng J, Li X, Huber MB, Luke A, Majumdar S, Link TM. Meniscal measurements of T1rho and T2 at MR imaging in healthy subjects and patients with osteoarthritis. Radiology. 2008 Nov; 249(2):591-600.
        View in: PubMed
      12. Stahl R, Luke A, Li X, Carballido-Gamio J, Ma CB, Majumdar S, Link TM. T1rho, T2 and focal knee cartilage abnormalities in physically active and sedentary healthy subjects versus early OA patients--a 3.0-Tesla MRI study. Eur Radiol. 2009 Jan; 19(1):132-43.
        View in: PubMed
      13. Stahl R, Luke A, Ma CB, Krug R, Steinbach L, Majumdar S, Link TM. Prevalence of pathologic findings in asymptomatic knees of marathon runners before and after a competition in comparison with physically active subjects-a 3.0 T magnetic resonance imaging study. Skeletal Radiol. 2008 Jul; 37(7):627-38.
        View in: PubMed
      14. Luke AC, Bergeron MF, Roberts WO. Heat injury prevention practices in high school football. Clin J Sport Med. 2007 Nov; 17(6):488-93.
        View in: PubMed
      15. Luke A, d'Hemecourt P. Prevention of infectious diseases in athletes. Clin Sports Med. 2007 Jul; 26(3):321-44.
        View in: PubMed
      16. Iyengar J, Luke A, Ma CB. An unusual presentation of synovial chondromatosis of the knee: a case report. Clin J Sport Med. 2007 Mar; 17(2):157-9.
        View in: PubMed
      17. Luke A, Ma CB. Exertional thigh pain in a runner. Curr Sports Med Rep. 2006 Sep; 5(5):251-3.
        View in: PubMed
      18. Bergeron MF, McKeag DB, Casa DJ, Clarkson PM, Dick RW, Eichner ER, Horswill CA, Luke AC, Mueller F, Munce TA, Roberts WO, Rowland TW. Youth football: heat stress and injury risk. Med Sci Sports Exerc. 2005 Aug; 37(8):1421-30.
        View in: PubMed
      19. Luke A, Philpott J, Brett K, Cruz L, Lun V, Prasad N, Zetaruk M. Physical inactivity in children and adolescents: CASM AdHoc Committee on Children's Fitness. Clin J Sport Med. 2004 Sep; 14(5):261-6; discussion 260.
        View in: PubMed
      20. Kocher MS, Micheli LJ, Zurakowski D, Luke A. Partial tears of the anterior cruciate ligament in children and adolescents. Am J Sports Med. 2002 Sep-Oct; 30(5):697-703.
        View in: PubMed
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