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Thomas Link, MD, PhD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentRadiology
Address400 Parnassus Avenue
San Francisco CA 94117
Phone415-353-2450
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    Johannes Gutenberg UniversityM.D.1987School of Medicine
    Collapse Awards and Honors
    International Society for Magnetic Resonance in Medicine2017Senior Fellow Award
    Osteoarthritis&Cartilage2017Outstanding Reviewer Award
    Academy of Radiology Research2016Distinguished Investigator Award
    Skeletal Radiology 2014Certificate of Special Distinction
    The Journal of Othopaedic and Sports Physical Therapy2012George J. Davies - James A. Gould, Excellence in Clinical Inquiry Award
    Current Radiology Reports2012Editor-in-Chief
    Radiology2011Editor’s Recognition Award with Distinction
    International Skeletal Society, Washington2009The Founder's Lecturer
    European Journal of Radiology2007  - 2008Editors Recognition
    World Congress on Osteoarthritis, Prague. Czech Republic2007Plenary Lecturer
    Osteoporosis Group of the European Society of Skeletal Radiology (ESSR)2006Appointed Chairman
    Osteoarthritis and Cartilage 2006  - 2008Top Cited Award
    Medical School of the Technical University of Munich, Germany2000Teaching Award
    Society of Pediatric Radiology 1997Caffey Award

    Collapse Overview 
    Collapse Overview
    Thomas M. Link, MD, PhD, is Chief of the Musculoskeletal Imaging Section and Clinical Director of the Musculoskeletal and Quantitative Imaging Research (MQIR) Group in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. Dr. Link completed his medical residency in Muenster, Germany. He performed a research fellowship at the University of California, San Francisco in 1996 and was a Visiting Associate Professor at UCSF from 1999-2001. Before joining the Department of Radiology and Biomedical Imaging in 2003 he was a Vice-Chair of the Department of Radiology at the Technical University of Munich.

    As Clinical Director of the Musculoskeletal and Quantitative Imaging Research (MQIR) Group, Dr. Link’s main interest is translational research. He wants to provide clinical background to basic science researchers, assessing clinical feasibility of research projects and to apply new imaging techniques in clinical studies.

    Dr. Link’s research program in MQIR has five main focuses: imaging of osteoporosis, particularly developing new imaging techniques for assessment of bone quality and density, application on new imaging techniques for the clinical assessment of osteoarthritis, cartilage and prevention of cartilage degeneration, new imaging sequences for musculoskeletal imaging at high field, and MR guided high intensity focused ultrasound for treatment of osseous abnormalities.

    Dr. Link has published extensively with more than 400 peer-reviewed articles, 48 review articles, 47 book chapters, and 3 books.

    Expertise:
    Musculoskeletal Radiology

    Specialty:
    Bone tumors and interventional procedures, osteoporosis and osteoarthritis

    Professional Interests:
    New techniques for musculoskeletal imaging, osteoporosis, osteoarthritis, cartilage imaging, high field musculoskeletal MRI at 3.0 and 7.0T, MR-guided focused ultrasound

    Education and Training:
    • Medical School: Johannes-Gutenberg University, Mainz, Germany
    • Medical School: Groote Schuur Hospital University of Cape Town, Cape Town, RSA
    • Internship: City Hospital Idar-Oberstein, Teaching Hospital of the Johannes-Gutenberg, Mainz Germany
    • Residency: Department of Radiology Center for Rheumatic Diseases of the State of Rheinland-Pfalz, Bad Kreuznach, Germany
    • Residency: Department of Radiology, KKH Hellersen, Teaching Hospital of the University of Bonn, Germany
    • Residency: Department of Radiology, University Hospital, Muenster
    • Fellowship: University of California, San Francisco Department of Radiology
    • Doctor of Philosophy: University Hospital, Muenster Department of Radiology
    • Board Examination in Radiology (including Radiation Therapy), Muenster, Germany
    • Board Examination in Diagnostic Radiology, Muenster, Germany
    • ECFMG (USMLE, Step 1 and 2)
    • Temporary California License
    • USMLE Step 3
    • DEA License
    • Permanent California License
    • Fluoroscopy Supervisor License
    • Equivalence certification of Doctor of Philosophy (Ph.D.) degree in Medicine (for German qualifications) by Center for Educational Documentation, Boston
    • Diagnostic Radiology Core Exam, American Board of Radiology
    • Board Certification Diagnostic Radiology, American Board of Radiology


    Collapse Research 
    Collapse Research Activities and Funding
    Impact of Weight loss on Knee Joint Biochemical and Structural Degeneration
    NIH/NIAMS R01AR064771Aug 1, 2014 - Jul 31, 2019
    Role: Principal Investigator
    Translation of Quantitative Imaging in Osteoarthritis
    NIH/NIAMS P50AR060752Aug 1, 2011 - Jul 31, 2016
    Role: Co-Investigator
    T2 Relaxation Time of Knee Cartilage in the OAI Incidence Subcohort
    NIH/NIAMS U01AR059507Aug 1, 2010 - Jun 30, 2014
    Role: Principal Investigator
    Cortical Bone Porosity Identifies Diabetes Subjects With Fragility Fractures
    NIH/NIAMS RC1AR058405Sep 30, 2009 - Aug 31, 2012
    Role: Principal Investigator
    Biomedical Imaging for Clinician Scientists
    NIH/NIBIB T32EB001631Jan 1, 2004 - Jun 30, 2020
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Grace T, Neumann J, Samaan MA, Souza RB, Majumdar S, Link T, Zhang AL. Using the Scoring Hip Osteoarthritis with Magnetic Resonance Imaging (SHOMRI) System to Assess Intra-articular Pathology in Femoroacetabular Impingement. J Orthop Res. 2018 Jun 27. PMID: 29947434.
      View in: PubMed
    2. Baal JD, Horvai AE, Link T. Progression of dialysis-related amyloidoma towards pathologic fracture. Skeletal Radiol. 2018 Jun 26. PMID: 29946879.
      View in: PubMed
    3. Link T. Editorial comment: the future of compositional MRI for cartilage. Eur Radiol. 2018 Apr 30. PMID: 29713777.
      View in: PubMed
    4. Teng HL, Pedoia V, Link T, Majumdar S, Souza RB. Local associations between knee cartilage T1? and T2 relaxation times and patellofemoral joint stress during walking: A voxel-based relaxometry analysis. Knee. 2018 Apr 19. PMID: 29681528.
      View in: PubMed
    5. Link T, Li X. Establishing compositional MRI of cartilage as a biomarker for clinical practice. Osteoarthritis Cartilage. 2018 Mar 15. PMID: 29550402.
      View in: PubMed
    6. Guimaraes JB, Facchetti L, Schwaiger BJ, Gersing AS, Li X, Link T. Natural evolution of popliteomeniscal fascicle tears over 2 years and its association with lateral articular knee cartilage degeneration in patients with traumatic anterior cruciate ligament tear. Eur Radiol. 2018 Feb 23. PMID: 29476215.
      View in: PubMed
    7. Joseph GB, McCulloch CE, Nevitt MC, Neumann J, Gersing AS, Kretzschmar M, Schwaiger BJ, Lynch JA, Heilmeier U, Lane NE, Link T. Tool for osteoarthritis risk prediction (TOARP) over 8 years using baseline clinical data, X-ray, and MRI: Data from the osteoarthritis initiative. J Magn Reson Imaging. 2017 Nov 16. PMID: 29143404.
      View in: PubMed
    8. Guimaraes JB, Nevitt MC, McCulloch CE, Schwaiger BJ, Gersing AS, Facchetti L, Bucknor MD, Chanchek N, Liu F, Joseph GB, Link T. Association of weight change with progression of meniscal intrasubstance degeneration over 48 months: Data from the Osteoarthritis Initiative. Eur Radiol. 2017 Oct 06. PMID: 28986637.
      View in: PubMed
    9. Shimizu T, Choi HJ, Heilmeier U, Tanaka M, Burghardt AJ, Gong J, Chanchek N, Link T, Graf J, Imboden JB, Li X. Assessment of 3-month changes in bone microstructure under anti-TNFa therapy in patients with rheumatoid arthritis using high-resolution peripheral quantitative computed tomography (HR-pQCT). Arthritis Res Ther. 2017 Oct 04; 19(1):222. PMID: 28978352.
      View in: PubMed
    10. Schwaiger BJ, Mbapte Wamba J, Gersing AS, Nevitt MC, Facchetti L, McCulloch CE, Link T. Hyperintense signal alteration in the suprapatellar fat pad on MRI is associated with degeneration of the patellofemoral joint over 48 months: data from the Osteoarthritis Initiative. Skeletal Radiol. 2018 Mar; 47(3):329-339. PMID: 28944439.
      View in: PubMed
    11. Hofmann FC, Neumann J, Heilmeier U, Joseph GB, Nevitt MC, McCulloch CE, Link T. Conservatively treated knee injury is associated with knee cartilage matrix degeneration measured with MRI-based T2 relaxation times: data from the osteoarthritis initiative. Skeletal Radiol. 2018 Jan; 47(1):93-106. PMID: 28852821.
      View in: PubMed
    12. Samaan MA, Pedoia V, Zhang AL, Gallo MC, Link T, Souza RB, Majumdar S. A novel mr-based method for detection of cartilage delamination in femoroacetabular impingement patients. J Orthop Res. 2018 Mar; 36(3):971-978. PMID: 28762536.
      View in: PubMed
    13. Chanchek N, Gersing AS, Schwaiger BJ, Nevitt MC, Neumann J, Joseph GB, Lane NE, Zarnowski J, Hofmann FC, Heilmeier U, McCulloch CE, Link T. Association of diabetes mellitus and biochemical knee cartilage composition assessed by T2 relaxation time measurements: Data from the osteoarthritis initiative. J Magn Reson Imaging. 2018 Feb; 47(2):380-390. PMID: 28556419.
      View in: PubMed
    14. Holmes MG, Foss E, Joseph G, Foye A, Beckett B, Motamedi D, Youngren J, Thomas GV, Huang J, Aggarwal R, Alumkal JJ, Beer TM, Small EJ, Link T. CT-Guided Bone Biopsies in Metastatic Castration-Resistant Prostate Cancer: Factors Predictive of Maximum Tumor Yield. J Vasc Interv Radiol. 2017 Aug; 28(8):1073-1081.e1. PMID: 28549709.
      View in: PubMed
    15. Morgan TA, Piper SL, Lattanza LL, Goldstein RB, Link T, Motamedi D. Distal Forearm Fracture Open Reduction-Internal Fixation: Sonographic Detection of Hardware Malalignment and Associated Tendon Injuries Missed by Radiography. J Ultrasound Med. 2017 Oct; 36(10):2173-2177. PMID: 28503753.
      View in: PubMed
    16. Gersing AS, Schwaiger BJ, Nevitt MC, Joseph GB, Chanchek N, Guimaraes JB, Mbapte Wamba J, Facchetti L, McCulloch CE, Link T. Is Weight Loss Associated with Less Progression of Changes in Knee Articular Cartilage among Obese and Overweight Patients as Assessed with MR Imaging over 48 Months? Data from the Osteoarthritis Initiative. Radiology. 2017 08; 284(2):508-520. PMID: 28463057.
      View in: PubMed
    17. Schwaiger BJ, Kopperdahl DL, Nardo L, Facchetti L, Gersing AS, Neumann J, Lee KJ, Keaveny TM, Link T. Vertebral and femoral bone mineral density and bone strength in prostate cancer patients assessed in phantomless PET/CT examinations. Bone. 2017 Aug; 101:62-69. PMID: 28442297.
      View in: PubMed
    18. Joseph GB, McCulloch CE, Nevitt MC, Gersing AS, Schwaiger BJ, Kretzschmar M, Heilmeier U, Link T. Medial femur T2 Z-scores predict the probability of knee structural worsening over 4-8 years: Data from the osteoarthritis initiative. J Magn Reson Imaging. 2017 Oct; 46(4):1128-1136. PMID: 28206712.
      View in: PubMed
    19. Samaan MA, Facchetti L, Pedoia V, Tanaka MS, Link T, Souza RB, Ma CB, Li X. Cyclops lesions are associated with altered gait patterns and medial knee joint cartilage degeneration at 1 year after ACL-reconstruction. J Orthop Res. 2017 10; 35(10):2275-2281. PMID: 28128475.
      View in: PubMed
    20. Link T, Neumann J, Li X. Prestructural cartilage assessment using MRI. J Magn Reson Imaging. 2017 Apr; 45(4):949-965. PMID: 28019053.
      View in: PubMed
    21. Samaan MA, Schwaiger BJ, Gallo MC, Sada K, Link T, Zhang AL, Majumdar S, Souza RB. Joint Loading in the Sagittal Plane During Gait Is Associated With Hip Joint Abnormalities in Patients With Femoroacetabular Impingement. Am J Sports Med. 2017 Mar; 45(4):810-818. PMID: 28006109.
      View in: PubMed
    22. Facchetti L, Schwaiger BJ, Gersing AS, Guimaraes JB, Nardo L, Majumdar S, Ma BC, Link T, Li X. Cyclops lesions detected by MRI are frequent findings after ACL surgical reconstruction but do not impact clinical outcome over 2 years. Eur Radiol. 2017 Aug; 27(8):3499-3508. PMID: 27986989.
      View in: PubMed
    23. Gong J, Pedoia V, Facchetti L, Link T, Ma CB, Li X. Bone marrow edema-like lesions (BMELs) are associated with higher T1? and T2 values of cartilage in anterior cruciate ligament (ACL)-reconstructed knees: a longitudinal study. Quant Imaging Med Surg. 2016 Dec; 6(6):661-670. PMID: 28090444.
      View in: PubMed
    24. Guimaraes JB, Facchetti L, Schwaiger BJ, Gersing AS, Majumdar S, Ma BC, Li X, Link T. Evolution of Intrameniscal Signal-Intensity Alterations Detected on MRI Over 24 Months in Patients With Traumatic Anterior Cruciate Ligament Tear. AJR Am J Roentgenol. 2017 Feb; 208(2):386-392. PMID: 27824492.
      View in: PubMed
    25. Link T, Heilmeier U. Bone Quality-Beyond Bone Mineral Density. Semin Musculoskelet Radiol. 2016 Jul; 20(3):269-278. PMID: 27741542.
      View in: PubMed
    26. Samaan MA, Schwaiger BJ, Gallo MC, Link T, Zhang AL, Majumdar S, Souza RB. Abnormal Joint Moment Distributions and Functional Performance During Sit-to-Stand in Femoroacetabular Impingement Patients. PM R. 2017 Jun; 9(6):563-570. PMID: 27729286.
      View in: PubMed
    27. Gersing AS, Schwaiger BJ, Heilmeier U, Joseph GB, Facchetti L, Kretzschmar M, Lynch JA, McCulloch CE, Nevitt MC, Steinbach LS, Link T. Evaluation of Chondrocalcinosis and Associated Knee Joint Degeneration Using MR Imaging: Data from the Osteoarthritis Initiative. Eur Radiol. 2017 Jun; 27(6):2497-2506. PMID: 27704199.
      View in: PubMed
    28. Heilmeier U, Hackl M, Skalicky S, Weilner S, Schroeder F, Vierlinger K, Patsch JM, Baum T, Oberbauer E, Lobach I, Burghardt AJ, Schwartz AV, Grillari J, Link T. Serum miRNA Signatures Are Indicative of Skeletal Fractures in Postmenopausal Women With and Without Type 2 Diabetes and Influence Osteogenic and Adipogenic Differentiation of Adipose Tissue-Derived Mesenchymal Stem Cells In Vitro. J Bone Miner Res. 2016 Dec; 31(12):2173-2192. PMID: 27345526.
      View in: PubMed
    29. Ku E, Pedoia V, Tanaka M, Heilmeier U, Imboden J, Graf J, Link T, Li X. Evaluating radiocarpal cartilage matrix changes 3-months after anti-TNF treatment for rheumatoid arthritis using MR T1? imaging. J Magn Reson Imaging. 2017 05; 45(5):1514-1522. PMID: 27661002.
      View in: PubMed
    30. Pedoia V, Su F, Amano K, Li Q, McCulloch CE, Souza RB, Link T, Ma BC, Li X. Analysis of the articular cartilage T1? and T2 relaxation times changes after ACL reconstruction in injured and contralateral knees and relationships with bone shape. J Orthop Res. 2017 03; 35(3):707-717. PMID: 27557479.
      View in: PubMed
    31. Trivedi H, Link T, O'Donnell RJ, Horvai AE, Motamedi D. Multiple hereditary exostoses: A pseudoaneurysm masquerading as tumor. J Radiol Case Rep. 2016 Aug; 10(8):50-59. PMID: 27761193.
      View in: PubMed
    32. Gutierrez LB, Link T, Chaganti K, Motamedi D. Arterial calcification due to CD73 deficiency (ACDC): imaging manifestations of ectopic mineralization. Skeletal Radiol. 2016 Nov; 45(11):1583-7. PMID: 27562569.
      View in: PubMed
    33. Burke C, Link T, O'Donnell RJ, Cho SJ, Motamedi D. Giant Cell Tumor of Bone: Documented Progression over 4 Years from Its Origin at the Metaphysis to the Articular Surface. Case Rep Radiol. 2016; 2016:9786925. PMID: 27630783; PMCID: PMC5005548.
    34. Leeman JJ, Motamedi D, Wildman-Tobriner B, O'Donnell RJ, Link T. Intra-articular osteoid osteoma at the femoral trochlea treated with osteochondral autograft transplantation. J Radiol Case Rep. 2016 Jun; 10(6):22-29. PMID: 27761182.
      View in: PubMed
    35. Patel R, Eltgroth M, Souza R, Zhang CA, Majumdar S, Link T, Motamedi D. Loaded versus unloaded magnetic resonance imaging (MRI) of the knee: Effect on meniscus extrusion in healthy volunteers and patients with osteoarthritis. Eur J Radiol Open. 2016; 3:100-7. PMID: 27331081; PMCID: PMC4906039.
    36. Samaan MA, Zhang AL, Gallo MC, Schwaiger BJ, Link T, Souza RB, Majumdar S. Quantitative magnetic resonance arthrography in patients with femoroacetabular impingement. J Magn Reson Imaging. 2016 Dec; 44(6):1539-1545. PMID: 27192497.
      View in: PubMed
    37. Schwaiger BJ, Gersing AS, Mbapte Wamba J, Nevitt MC, McCulloch CE, Link T. Can Signal Abnormalities Detected with MR Imaging in Knee Articular Cartilage Be Used to Predict Development of Morphologic Cartilage Defects? 48-Month Data from the Osteoarthritis Initiative. Radiology. 2016 10; 281(1):158-67. PMID: 27135833.
      View in: PubMed
    38. Schwaiger BJ, Gersing AS, Lee S, Nardo L, Samaan MA, Souza RB, Link T, Majumdar S. Longitudinal assessment of MRI in hip osteoarthritis using SHOMRI and correlation with clinical progression. Semin Arthritis Rheum. 2016 06; 45(6):648-55. PMID: 27162009; PMCID: PMC4879061 [Available on 06/01/17].
    39. Joseph GB, Hou SW, Nardo L, Heilmeier U, Nevitt MC, McCulloch CE, Link T. MRI findings associated with development of incident knee pain over 48 months: data from the osteoarthritis initiative. Skeletal Radiol. 2016 May; 45(5):653-60. PMID: 26919860; PMCID: PMC4815898 [Available on 05/01/17].
    40. Pedoia V, Majumdar S, Link T. Segmentation of joint and musculoskeletal tissue in the study of arthritis. MAGMA. 2016 Apr; 29(2):207-21. PMID: 26915082.
      View in: PubMed
    41. Heilmeier U, Youm J, Torabi S, Link T. Osteoporosis Imaging in the Geriatric Patient. Curr Radiol Rep. 2016 Apr; 4(4). PMID: 27482472.
      View in: PubMed
    42. Gersing AS, Link T. Imaging of Osteoarthritis in Geriatric Patients. Curr Radiol Rep. 2016 Jan; 4(1). PMID: 27162704.
      View in: PubMed
    43. Wang A, Pedoia V, Su F, Abramson E, Kretzschmar M, Nardo L, Link T, McCulloch CE, Jin C, Ma CB, Li X. MR T1? and T2 of meniscus after acute anterior cruciate ligament injuries. Osteoarthritis Cartilage. 2016 Apr; 24(4):631-9. PMID: 26620091.
      View in: PubMed
    44. Liu J, Pedoia V, Heilmeier U, Ku E, Su F, Khanna S, Imboden J, Graf J, Link T, Li X. High-temporospatial-resolution dynamic contrast-enhanced (DCE) wrist MRI with variable-density pseudo-random circular Cartesian undersampling (CIRCUS) acquisition: evaluation of perfusion in rheumatoid arthritis patients. NMR Biomed. 2016 Jan; 29(1):15-23. PMID: 26608949; PMCID: PMC4724417 [Available on 01/01/17].
    45. Nardo L, Han M, Kretzschmar M, Guindani M, Koch K, Vail T, Krug R, Link T. Erratum to: Metal artifact suppression at the hip: diagnostic performance at 3.0 T versus 1.5 Tesla. Skeletal Radiol. 2015 Nov; 44(11):1617. PMID: 26298104.
      View in: PubMed
    46. Hackney LA, Lee MH, Joseph GB, Vail TP, Link T. Subchondral insufficiency fractures of the femoral head: associated imaging findings and predictors of clinical progression. Eur Radiol. 2016 Jun; 26(6):1929-41. PMID: 26334506.
      View in: PubMed
    47. Link T, Schwaiger BJ, Zhang AL. Regional Articular Cartilage Abnormalities of the Hip. AJR Am J Roentgenol. 2015 Sep; 205(3):502-12. PMID: 26295636.
      View in: PubMed
    48. Plett SK, Hackney LA, Heilmeier U, Nardo L, Yu A, Zhang CA, Link T. Femoral condyle insufficiency fractures: associated clinical and morphological findings and impact on outcome. Skeletal Radiol. 2015 Dec; 44(12):1785-94. PMID: 26290325.
      View in: PubMed
    49. Calixto NE, Kumar D, Subburaj K, Singh J, Schooler J, Nardo L, Li X, Souza RB, Link T, Majumdar S. Zonal differences in meniscus MR relaxation times in response to in vivo static loading in knee osteoarthritis. J Orthop Res. 2016 Feb; 34(2):249-61. PMID: 26223430.
      View in: PubMed
    50. Samaan MA, Teng HL, Kumar D, Lee S, Link T, Majumdar S, Souza RB. Acetabular cartilage defects cause altered hip and knee joint coordination variability during gait. Clin Biomech (Bristol, Avon). 2015 Dec; 30(10):1202-9. PMID: 26298706; PMCID: PMC4674371 [Available on 12/01/16].
    51. Nardo L, Parimi N, Liu F, Lee S, Jungmann PM, Nevitt MC, Link T, Lane NE. Femoroacetabular Impingement: Prevalent and Often Asymptomatic in Older Men: The Osteoporotic Fractures in Men Study. Clin Orthop Relat Res. 2015 Aug; 473(8):2578-86. PMID: 25736918; PMCID: PMC4488192.
    52. Kumar D, Souza RB, Subburaj K, MacLeod TD, Singh J, Calixto NE, Nardo L, Link T, Li X, Lane NE, Majumdar S. Are There Sex Differences in Knee Cartilage Composition and Walking Mechanics in Healthy and Osteoarthritis Populations? Clin Orthop Relat Res. 2015 Aug; 473(8):2548-58. PMID: 25716211; PMCID: PMC4488198.
    53. Nardo L, Han M, Kretzschmar M, Kretschmar M, Guindani M, Koch K, Vail T, Krug R, Link T. Metal artifact suppression at the hip: diagnostic performance at 3.0 T versus 1.5 Tesla. Skeletal Radiol. 2015 Nov; 44(11):1609-16. PMID: 26201676.
      View in: PubMed
    54. Teng HL, MacLeod TD, Link T, Majumdar S, Souza RB. Higher Knee Flexion Moment During the Second Half of the Stance Phase of Gait Is Associated With the Progression of Osteoarthritis of the Patellofemoral Joint on Magnetic Resonance Imaging. J Orthop Sports Phys Ther. 2015 Sep; 45(9):656-64. PMID: 26161626; PMCID: PMC4718079.
    55. Guha A, Wyatt C, Karampinos DC, Nardo L, Link T, Majumdar S. Spatial variations in magnetic resonance-based diffusion of articular cartilage in knee osteoarthritis. Magn Reson Imaging. 2015 Nov; 33(9):1051-1058. PMID: 26119421; PMCID: PMC4593725 [Available on 11/01/16].
    56. Link T. Radiology of Osteoporosis. Can Assoc Radiol J. 2016 Feb; 67(1):28-40. PMID: 26105503.
      View in: PubMed
    57. Lee S, Lucas RM, Lansdown DA, Nardo L, Lai A, Link T, Krug R, Ma CB. Magnetic resonance rotator cuff fat fraction and its relationship with tendon tear severity and subject characteristics. J Shoulder Elbow Surg. 2015 Sep; 24(9):1442-51. PMID: 25819731.
      View in: PubMed
    58. Teng HL, MacLeod TD, Kumar D, Link T, Majumdar S, Souza RB. Individuals with isolated patellofemoral joint osteoarthritis exhibit higher mechanical loading at the knee during the second half of the stance phase. Clin Biomech (Bristol, Avon). 2015 May; 30(4):383-90. PMID: 25726158; PMCID: PMC4404202.
    59. Kretzschmar M, Nardo L, Han MM, Heilmeier U, Sam C, Joseph GB, Koch KM, Krug R, Link T. Metal artefact suppression at 3 T MRI: comparison of MAVRIC-SL with conventional fast spin echo sequences in patients with Hip joint arthroplasty. Eur Radiol. 2015 Aug; 25(8):2403-11. PMID: 25680728.
      View in: PubMed
    60. Kumar D, Wyatt C, Chiba K, Lee S, Nardo L, Link T, Majumdar S, Souza RB. Anatomic correlates of reduced hip extension during walking in individuals with mild-moderate radiographic hip osteoarthritis. J Orthop Res. 2015 Apr; 33(4):527-34. PMID: 25678302; PMCID: PMC4376613.
    61. Lance V, Heilmeier UR, Joseph GB, Steinbach L, Ma B, Link T. MR imaging characteristics and clinical symptoms related to displaced meniscal flap tears. Skeletal Radiol. 2015 Mar; 44(3):375-84. PMID: 25398362.
      View in: PubMed
    62. Kumar D, Souza RB, Singh J, Calixto NE, Nardo L, Link T, Li X, Majumdar S. Physical activity and spatial differences in medial knee T1rho and t2 relaxation times in knee osteoarthritis. J Orthop Sports Phys Ther. 2014 Dec; 44(12):964-72. PMID: 25353261; PMCID: PMC4476033.
    63. Bucknor MD, Rieke V, Seo Y, Horvai AE, Hawkins RA, Majumdar S, Link T, Saeed M. Bone remodeling after MR imaging-guided high-intensity focused ultrasound ablation: evaluation with MR imaging, CT, Na(18)F-PET, and histopathologic examination in a swine model. Radiology. 2015 Feb; 274(2):387-94. PMID: 25302829.
      View in: PubMed
    64. Lee CH, Srikhum W, Burghardt AJ, Virayavanich W, Imboden JB, Link T, Li X. Correlation of structural abnormalities of the wrist and metacarpophalangeal joints evaluated by high-resolution peripheral quantitative computed tomography, 3 Tesla magnetic resonance imaging and conventional radiographs in rheumatoid arthritis. Int J Rheum Dis. 2015 Jul; 18(6):628-39. PMID: 25293500.
      View in: PubMed
    65. Lee S, Nardo L, Kumar D, Wyatt CR, Souza RB, Lynch J, McCulloch CE, Majumdar S, Lane NE, Link T. Scoring hip osteoarthritis with MRI (SHOMRI): A whole joint osteoarthritis evaluation system. J Magn Reson Imaging. 2015 Jun; 41(6):1549-57. PMID: 25139720; PMCID: PMC4336224.
    66. Gupta R, Virayavanich W, Kuo D, Su F, Link T, Ma B, Li X. MR T(1)? quantification of cartilage focal lesions in acutely injured knees: correlation with arthroscopic evaluation. Magn Reson Imaging. 2014 Dec; 32(10):1290-6. PMID: 25111625; PMCID: PMC4253653.
    67. Teruel JR, Burghardt AJ, Rivoire J, Srikhum W, Noworolski SM, Link T, Imboden JB, Li X. Bone structure and perfusion quantification of bone marrow edema pattern in the wrist of patients with rheumatoid arthritis: a multimodality study. J Rheumatol. 2014 Sep; 41(9):1766-73. PMID: 25086074.
      View in: PubMed
    68. Zhang AL, Gates CH, Link T, Ma CB. Abnormal origins of the long head of the biceps tendon can lead to rotator cuff pathology: a report of two cases. Skeletal Radiol. 2014 Nov; 43(11):1621-6. PMID: 24915738.
      View in: PubMed
    69. Liebl H, Heilmeier U, Lee S, Nardo L, Patsch J, Schuppert C, Han M, Rondak IC, Banerjee S, Koch K, Link T, Krug R. In vitro assessment of knee MRI in the presence of metal implants comparing MAVRIC-SL and conventional fast spin echo sequences at 1.5 and 3 T field strength. J Magn Reson Imaging. 2015 May; 41(5):1291-9. PMID: 24912802; PMCID: PMC4297744.
    70. Link T, Lang TF. Axial QCT: clinical applications and new developments. J Clin Densitom. 2014 Oct-Dec; 17(4):438-48. PMID: 24880494.
      View in: PubMed
    71. Serebrakian AT, Poulos T, Liebl H, Joseph GB, Lai A, Nevitt MC, Lynch JA, McCulloch CE, Link T. Weight loss over 48 months is associated with reduced progression of cartilage T2 relaxation time values: data from the osteoarthritis initiative. J Magn Reson Imaging. 2015 May; 41(5):1272-1280. PMID: 24700497; PMCID: PMC4185274.
    72. Kazakia GJ, Tjong W, Nirody JA, Burghardt AJ, Carballido-Gamio J, Patsch JM, Link T, Feeley BT, Ma CB. The influence of disuse on bone microstructure and mechanics assessed by HR-pQCT. Bone. 2014 Jun; 63:132-40. PMID: 24603002; PMCID: PMC4041600.
    73. Kumar D, Dillon A, Nardo L, Link T, Majumdar S, Souza RB. Differences in the association of hip cartilage lesions and cam-type femoroacetabular impingement with movement patterns: a preliminary study. PM R. 2014 Aug; 6(8):681-9. PMID: 24534097; PMCID: PMC4133316.
    74. Alizai H, Virayavanich W, Joseph GB, Nardo L, Liu F, Liebl H, Nevitt MC, Lynch JA, McCulloch CE, Link T. Cartilage lesion score: comparison of a quantitative assessment score with established semiquantitative MR scoring systems. Radiology. 2014 May; 271(2):479-87. PMID: 24475848; PMCID: PMC4263635.
    75. Subburaj K, Souza RB, Wyman BT, Le Graverand-Gastineau MP, Li X, Link T, Majumdar S. Changes in MR relaxation times of the meniscus with acute loading: an in vivo pilot study in knee osteoarthritis. J Magn Reson Imaging. 2015 Feb; 41(2):536-43. PMID: 24347310; PMCID: PMC4062611.
    76. Jungmann PM, Liu F, Link T. What has imaging contributed to the epidemiological understanding of osteoarthritis? Skeletal Radiol. 2014 Mar; 43(3):271-5. PMID: 24346338; PMCID: PMC3925496.
    77. Bauer JS, Sidorenko I, Mueller D, Baum T, Issever AS, Eckstein F, Rummeny EJ, Link T, Raeth CW. Prediction of bone strength by µCT and MDCT-based finite-element-models: how much spatial resolution is needed? Eur J Radiol. 2014 Jan; 83(1):e36-42. PMID: 24274992.
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    79. Kumar D, Subburaj K, Lin W, Karampinos DC, McCulloch CE, Li X, Link T, Souza RB, Majumdar S. Quadriceps and hamstrings morphology is related to walking mechanics and knee cartilage MRI relaxation times in young adults. J Orthop Sports Phys Ther. 2013 Dec; 43(12):881-90. PMID: 24175607; PMCID: PMC4476495.
    80. Solomon DA, Antonescu CR, Link T, O'Donnell RJ, Folpe AL, Horvai AE. Hemosiderotic fibrolipomatous tumor, not an entirely benign entity. Am J Surg Pathol. 2013 Oct; 37(10):1627-30. PMID: 24025526.
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    82. Jungmann PM, Kraus MS, Nardo L, Liebl H, Alizai H, Joseph GB, Liu F, Lynch J, McCulloch CE, Nevitt MC, Link T. T(2) relaxation time measurements are limited in monitoring progression, once advanced cartilage defects at the knee occur: longitudinal data from the osteoarthritis initiative. J Magn Reson Imaging. 2013 Dec; 38(6):1415-24. PMID: 24038491; PMCID: PMC4114220.
    83. Patsch JM, Zulliger MA, Vilayphou N, Samelson EJ, Cejka D, Diarra D, Berzaczy G, Burghardt AJ, Link T, Weber M, Loewe C. Quantification of lower leg arterial calcifications by high-resolution peripheral quantitative computed tomography. Bone. 2014 Jan; 58:42-7. PMID: 23954758; PMCID: PMC4042679.
    84. Bucknor MD, Gross AJ, Link T. Voriconazole-induced periostitis in two post-transplant patients. J Radiol Case Rep. 2013 Aug; 7(8):10-7. PMID: 24421948; PMCID: PMC3888175.
    85. Patsch JM, Li X, Baum T, Yap SP, Karampinos DC, Schwartz AV, Link T. Bone marrow fat composition as a novel imaging biomarker in postmenopausal women with prevalent fragility fractures. J Bone Miner Res. 2013 Aug; 28(8):1721-8. PMID: 23558967; PMCID: PMC3720702.
    86. Burghardt AJ, Lee CH, Kuo D, Majumdar S, Imboden JB, Link T, Li X. Quantitative in vivo HR-pQCT imaging of 3D wrist and metacarpophalangeal joint space width in rheumatoid arthritis. Ann Biomed Eng. 2013 Dec; 41(12):2553-64. PMID: 23887879; PMCID: PMC3823828.
    87. Nardo L, Sandman DN, Virayavanich W, Zhang L, Souza RB, Steinbach L, Guindani M, Link T. Bone marrow changes related to disuse. Eur Radiol. 2013 Dec; 23(12):3422-31. PMID: 23832388; PMCID: PMC4026184.
    88. Jungmann PM, Tham SC, Liebl H, Nevitt MC, McCulloch CE, Lynch J, Link T. Association of trochlear dysplasia with degenerative abnormalities in the knee: data from the Osteoarthritis Initiative. Skeletal Radiol. 2013 Oct; 42(10):1383-92. PMID: 23801099.
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    90. Chundru R, Baum T, Nardo L, Nevitt MC, Lynch J, McCulloch CE, Link T. Focal knee lesions in knee pairs of asymptomatic and symptomatic subjects with OA risk factors--data from the Osteoarthritis Initiative. Eur J Radiol. 2013 Aug; 82(8):e367-73. PMID: 23540944; PMCID: PMC3696431.
    91. Srikhum W, Virayavanich W, Burghardt AJ, Yu A, Link T, Imboden JB, Li X. Quantitative and semiquantitative bone erosion assessment on high-resolution peripheral quantitative computed tomography in rheumatoid arthritis. J Rheumatol. 2013 Apr; 40(4):408-16. PMID: 23418386.
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    93. Theologis AA, Haughom B, Liang F, Zhang Y, Majumdar S, Link T, Ma CB, Li X. Comparison of T1rho relaxation times between ACL-reconstructed knees and contralateral uninjured knees. Knee Surg Sports Traumatol Arthrosc. 2014 Feb; 22(2):298-307. PMID: 23370983; PMCID: PMC3692610.
    94. Ries MD, Link T. Monitoring and risk of progression of osteolysis after total hip arthroplasty. Instr Course Lect. 2013; 62:207-14. PMID: 23395026.
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    96. Srikhum W, Nardo L, Karampinos DC, Melkus G, Poulos T, Steinbach LS, Link T. Magnetic resonance imaging of ankle tendon pathology: benefits of additional axial short-tau inversion recovery imaging to reduce magic angle effects. Skeletal Radiol. 2013 Apr; 42(4):499-510. PMID: 23229628.
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    99. Souza RB, Feeley BT, Zarins ZA, Link T, Li X, Majumdar S. T1rho MRI relaxation in knee OA subjects with varying sizes of cartilage lesions. Knee. 2013 Mar; 20(2):113-9. PMID: 23159719; PMCID: PMC3568198.
    100. Jungmann PM, Li X, Nardo L, Subburaj K, Lin W, Ma CB, Majumdar S, Link T. Do cartilage repair procedures prevent degenerative meniscus changes?: longitudinal t1? and morphological evaluation with 3.0-T MRI. Am J Sports Med. 2012 Dec; 40(12):2700-8. PMID: 23104606; PMCID: PMC4074395.
    101. Valentinitsch A, Karampinos DC, Alizai H, Subburaj K, Kumar D, Link T, Majumdar S. Automated unsupervised multi-parametric classification of adipose tissue depots in skeletal muscle. J Magn Reson Imaging. 2013 Apr; 37(4):917-27. PMID: 23097409; PMCID: PMC3573225.
    102. Nardo L, Alizai H, Virayavanich W, Liu F, Hernandez A, Lynch JA, Nevitt MC, McCulloch CE, Lane NE, Link T. Lumbosacral transitional vertebrae: association with low back pain. Radiology. 2012 Nov; 265(2):497-503. PMID: 22952380; PMCID: PMC3480814.
    103. Stehling C, Souza RB, Hellio Le Graverand MP, Wyman BT, Li X, Majumdar S, Link T. Loading of the knee during 3.0T MRI is associated with significantly increased medial meniscus extrusion in mild and moderate osteoarthritis. Eur J Radiol. 2012 Aug; 81(8):1839-45. PMID: 21684704; PMCID: PMC3399044.
    104. Subburaj K, Kumar D, Souza RB, Alizai H, Li X, Link T, Majumdar S. The acute effect of running on knee articular cartilage and meniscus magnetic resonance relaxation times in young healthy adults. Am J Sports Med. 2012 Sep; 40(9):2134-41. PMID: 22729505; PMCID: PMC3660554.
    105. Link T. Osteoporosis imaging: state of the art and advanced imaging. Radiology. 2012 Apr; 263(1):3-17. PMID: 22438439; PMCID: PMC3309802.
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    107. Souza RB, Baum T, Wu S, Feeley BT, Kadel N, Li X, Link T, Majumdar S. Effects of unloading on knee articular cartilage T1rho and T2 magnetic resonance imaging relaxation times: a case series. J Orthop Sports Phys Ther. 2012 Jun; 42(6):511-20. PMID: 22402583; PMCID: PMC3673554.
    108. Hovis KK, Alizai H, Tham SC, Souza RB, Nevitt MC, McCulloch CE, Link T. Non-traumatic anterior cruciate ligament abnormalities and their relationship to osteoarthritis using morphological grading and cartilage T2 relaxation times: data from the Osteoarthritis Initiative (OAI). Skeletal Radiol. 2012 Nov; 41(11):1435-43. PMID: 22366737; PMCID: PMC3586320.
    109. Zuo J, Joseph GB, Li X, Link T, Hu SS, Berven SH, Kurhanewitz J, Majumdar S. In vivo intervertebral disc characterization using magnetic resonance spectroscopy and T1? imaging: association with discography and Oswestry Disability Index and Short Form-36 Health Survey. Spine (Phila Pa 1976). 2012 Feb 01; 37(3):214-21. PMID: 21697767; PMCID: PMC3633556.
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    112. Prasad AP, George V, Porzig A, Horvai AE, Gross A, Shoback D, Link T. Progressive craniofacial bone loss after cosmetic surgery at the forehead. Skeletal Radiol. 2012 Apr; 41(4):477-81. PMID: 22127344.
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    116. Li X, Yu A, Virayavanich W, Noworolski SM, Link T, Imboden J. Quantitative characterization of bone marrow edema pattern in rheumatoid arthritis using 3 Tesla MRI. J Magn Reson Imaging. 2012 Jan; 35(1):211-7. PMID: 21987483.
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    129. Cotofana S, Eckstein F, Wirth W, Souza RB, Li X, Wyman B, Hellio-Le Graverand MP, Link T, Majumdar S. In vivo measures of cartilage deformation: patterns in healthy and osteoarthritic female knees using 3T MR imaging. Eur Radiol. 2011 Jun; 21(6):1127-35. PMID: 21448616; PMCID: PMC3088828.
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    131. Sode M, Burghardt AJ, Pialat JB, Link T, Majumdar S. Quantitative characterization of subject motion in HR-pQCT images of the distal radius and tibia. Bone. 2011 Jun 01; 48(6):1291-7. PMID: 21421091; PMCID: PMC3108045.
    132. Tham SC, Horvai AE, Link T, Steinbach L. Soft tissue mass at the infrascapular fossa. Skeletal Radiol. 2011 Jan; 40(1):105-6, 123-4. PMID: 21072631; PMCID: PMC2989001.
    133. Li X, Kuo D, Theologis A, Carballido-Gamio J, Stehling C, Link T, Ma CB, Majumdar S. Cartilage in anterior cruciate ligament-reconstructed knees: MR imaging T1{rho} and T2--initial experience with 1-year follow-up. Radiology. 2011 Feb; 258(2):505-14. PMID: 21177392; PMCID: PMC3029884.
    134. Li X, Cheng J, Lin K, Saadat E, Bolbos RI, Jobke B, Ries MD, Horvai A, Link T, Majumdar S. Quantitative MRI using T1? and T2 in human osteoarthritic cartilage specimens: correlation with biochemical measurements and histology. Magn Reson Imaging. 2011 Apr; 29(3):324-34. PMID: 21130590; PMCID: PMC3058148.
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    136. Folkesson J, Goldenstein J, Carballido-Gamio J, Kazakia G, Burghardt AJ, Rodriguez A, Krug R, de Papp AE, Link T, Majumdar S. Longitudinal evaluation of the effects of alendronate on MRI bone microarchitecture in postmenopausal osteopenic women. Bone. 2011 Mar 01; 48(3):611-21. PMID: 21059422; PMCID: PMC4461063.
    137. Rodríguez-Soto AE, Fritscher KD, Schuler B, Issever AS, Roth T, Kamelger F, Kammerlander C, Blauth M, Schubert R, Link T. Texture analysis, bone mineral density, and cortical thickness of the proximal femur: fracture risk prediction. J Comput Assist Tomogr. 2010 Nov-Dec; 34(6):949-57. PMID: 21084915.
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    139. Burghardt AJ, Issever AS, Schwartz AV, Davis KA, Masharani U, Majumdar S, Link T. High-resolution peripheral quantitative computed tomographic imaging of cortical and trabecular bone microarchitecture in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab. 2010 Nov; 95(11):5045-55. PMID: 20719835; PMCID: PMC2968722.
    140. Virayavanich W, Singh R, O'Donnell RJ, Horvai AE, Goldsby RE, Link T. Osteoid osteoma of the femur in a 7-month-old infant treated with radiofrequency ablation. Skeletal Radiol. 2010 Nov; 39(11):1145-9. PMID: 20694724; PMCID: PMC2939336.
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    142. Luke AC, Stehling C, Stahl R, Li X, Kay T, Takamoto S, Ma B, Majumdar S, Link T. High-field magnetic resonance imaging assessment of articular cartilage before and after marathon running: does long-distance running lead to cartilage damage? Am J Sports Med. 2010 Nov; 38(11):2273-80. PMID: 20631252.
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    145. Burghardt AJ, Kazakia GJ, Sode M, de Papp AE, Link T, Majumdar S. A longitudinal HR-pQCT study of alendronate treatment in postmenopausal women with low bone density: Relations among density, cortical and trabecular microarchitecture, biomechanics, and bone turnover. J Bone Miner Res. 2010 Dec; 25(12):2558-71. PMID: 20564242; PMCID: PMC3179276.
    146. Blumenkrantz G, Zuo J, Li X, Kornak J, Link T, Majumdar S. In vivo 3.0-tesla magnetic resonance T1rho and T2 relaxation mapping in subjects with intervertebral disc degeneration and clinical symptoms. Magn Reson Med. 2010 May; 63(5):1193-200. PMID: 20432290; PMCID: PMC2988488.
    147. Burghardt AJ, Kazakia GJ, Ramachandran S, Link T, Majumdar S. Age- and gender-related differences in the geometric properties and biomechanical significance of intracortical porosity in the distal radius and tibia. J Bone Miner Res. 2010 May; 25(5):983-93. PMID: 19888900; PMCID: PMC3153365.
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    149. Tham SC, Horvai AE, Link T, Steinbach L. Soft tissue mass at the infrascapular fossa. Skeletal Radiol. 2010 Apr 15. PMID: 20393710.
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    152. Zhao J, Li X, Bolbos RI, Link T, Majumdar S. Longitudinal assessment of bone marrow edema-like lesions and cartilage degeneration in osteoarthritis using 3 T MR T1rho quantification. Skeletal Radiol. 2010 Jun; 39(6):523-31. PMID: 20195865; PMCID: PMC2929817.
    153. Sode M, Burghardt AJ, Kazakia GJ, Link T, Majumdar S. Regional variations of gender-specific and age-related differences in trabecular bone structure of the distal radius and tibia. Bone. 2010 Jun; 46(6):1652-60. PMID: 20188877; PMCID: PMC2875319.
    154. Carballido-Gamio J, Blumenkrantz G, Lynch JA, Link T, Majumdar S. Longitudinal analysis of MRI T(2) knee cartilage laminar organization in a subset of patients from the osteoarthritis initiative. Magn Reson Med. 2010 Feb; 63(2):465-72. PMID: 19918905.
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    157. Stehling C, Liebl H, Krug R, Lane NE, Nevitt MC, Lynch J, McCulloch CE, Link T. Patellar cartilage: T2 values and morphologic abnormalities at 3.0-T MR imaging in relation to physical activity in asymptomatic subjects from the osteoarthritis initiative. Radiology. 2010 Feb; 254(2):509-20. PMID: 20019141; PMCID: PMC2809928.
    158. Zuo J, Saadat E, Romero A, Loo K, Li X, Link T, Kurhanewicz J, Majumdar S. Assessment of intervertebral disc degeneration with magnetic resonance single-voxel spectroscopy. Magn Reson Med. 2009 Nov; 62(5):1140-6. PMID: 19780173; PMCID: PMC4277890.
    159. Krug R, Stehling C, Kelley DA, Majumdar S, Link T. Imaging of the musculoskeletal system in vivo using ultra-high field magnetic resonance at 7 T. Invest Radiol. 2009 Sep; 44(9):613-8. PMID: 19652609.
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    161. Bauer JS, Link T. Advances in osteoporosis imaging. Eur J Radiol. 2009 Sep; 71(3):440-9. PMID: 19651482.
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    164. Daldrup-Link HE, Mohanty A, Cuenod C, Pichler B, Link T. New perspectives on bone marrow contrast agents and molecular imaging. Semin Musculoskelet Radiol. 2009 Jun; 13(2):145-56. PMID: 19455477.
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    165. Wong S, Steinbach L, Zhao J, Stehling C, Ma CB, Link T. Comparative study of imaging at 3.0 T versus 1.5 T of the knee. Skeletal Radiol. 2009 Aug; 38(8):761-9. PMID: 19350234; PMCID: PMC2704948.
    166. Zhao J, Krug R, Xu D, Lu Y, Link T. MRI of the spine: image quality and normal-neoplastic bone marrow contrast at 3 T versus 1.5 T. AJR Am J Roentgenol. 2009 Apr; 192(4):873-80. PMID: 19304689.
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    167. Folkesson J, Krug R, Goldenstein J, Issever AS, Fang C, Link T, Majumdar S. Evaluation of correction methods for coil-induced intensity inhomogeneities and their influence on trabecular bone structure parameters from MR images. Med Phys. 2009 Apr; 36(4):1267-74. PMID: 19472635.
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    168. Stahl R, Krug R, Kelley DA, Zuo J, Ma CB, Majumdar S, Link T. Assessment of cartilage-dedicated sequences at ultra-high-field MRI: comparison of imaging performance and diagnostic confidence between 3.0 and 7.0 T with respect to osteoarthritis-induced changes at the knee joint. Skeletal Radiol. 2009 Aug; 38(8):771-83. PMID: 19294379; PMCID: PMC2704950.
    169. Guglielmi G, Adams J, Link T. Quantitative ultrasound in the assessment of skeletal status. Eur Radiol. 2009 Aug; 19(8):1837-48. PMID: 19259681.
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    170. Zhao J, Link T. MRI in degenerative arthritides: structural and clinical aspects. Ann N Y Acad Sci. 2009 Feb; 1154:115-35. PMID: 19250234.
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    171. Link T. Correlations between joint morphology and pain and between magnetic resonance imaging, histology, and micro-computed tomography. J Bone Joint Surg Am. 2009 Feb; 91 Suppl 1:30-2. PMID: 19182020.
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    172. Carballido-Gamio J, Krug R, Huber MB, Hyun B, Eckstein F, Majumdar S, Link T. Geodesic topological analysis of trabecular bone microarchitecture from high-spatial resolution magnetic resonance images. Magn Reson Med. 2009 Feb; 61(2):448-56. PMID: 19161163; PMCID: PMC4445730.
    173. Ristow O, Steinbach L, Sabo G, Krug R, Huber M, Rauscher I, Ma B, Link T. Isotropic 3D fast spin-echo imaging versus standard 2D imaging at 3.0 T of the knee--image quality and diagnostic performance. Eur Radiol. 2009 May; 19(5):1263-72. PMID: 19137309.
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    174. Rauscher I, Stahl R, Cheng J, Li X, Huber MB, Luke A, Majumdar S, Link T. Meniscal measurements of T1rho and T2 at MR imaging in healthy subjects and patients with osteoarthritis. Radiology. 2008 Nov; 249(2):591-600. PMID: 18936315; PMCID: PMC2657859.
    175. Bolbos RI, Ma CB, Link T, Majumdar S, Li X. In vivo T1rho quantitative assessment of knee cartilage after anterior cruciate ligament injury using 3 Tesla magnetic resonance imaging. Invest Radiol. 2008 Nov; 43(11):782-8. PMID: 18923257; PMCID: PMC2838766.
    176. Cabarrus MC, Ambekar A, Lu Y, Link T. MRI and CT of insufficiency fractures of the pelvis and the proximal femur. AJR Am J Roentgenol. 2008 Oct; 191(4):995-1001. PMID: 18806133.
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    177. Blumenfeld J, Studholme C, Carballido-Gamio J, Carpenter D, Link T, Majumdar S. Three-dimensional image registration of MR proximal femur images for the analysis of trabecular bone parameters. Med Phys. 2008 Oct; 35(10):4630-9. PMID: 18975709; PMCID: PMC2673590.
    178. Link T. In vivo quantification of cortical bone water with ultrashort echo-time MR imaging: a new parameter to measure bone quality? Radiology. 2008 Sep; 248(3):705-6. PMID: 18710965.
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    179. Stahl R, Luke A, Li X, Carballido-Gamio J, Ma CB, Majumdar S, Link T. T1rho, T2 and focal knee cartilage abnormalities in physically active and sedentary healthy subjects versus early OA patients--a 3.0-Tesla MRI study. Eur Radiol. 2009 Jan; 19(1):132-43. PMID: 18709373.
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    180. Li X, Ma BC, Bolbos RI, Stahl R, Lozano J, Zuo J, Lin K, Link T, Safran M, Majumdar S. Quantitative assessment of bone marrow edema-like lesion and overlying cartilage in knees with osteoarthritis and anterior cruciate ligament tear using MR imaging and spectroscopic imaging at 3 Tesla. J Magn Reson Imaging. 2008 Aug; 28(2):453-61. PMID: 18666183; PMCID: PMC2666932.
    181. Carballido-Gamio J, Link T, Li X, Han ET, Krug R, Ries MD, Majumdar S. Feasibility and reproducibility of relaxometry, morphometric, and geometrical measurements of the hip joint with magnetic resonance imaging at 3T. J Magn Reson Imaging. 2008 Jul; 28(1):227-35. PMID: 18581346.
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    182. Carballido-Gamio J, Link T, Majumdar S. New techniques for cartilage magnetic resonance imaging relaxation time analysis: texture analysis of flattened cartilage and localized intra- and inter-subject comparisons. Magn Reson Med. 2008 Jun; 59(6):1472-7. PMID: 18506807; PMCID: PMC2838770.
    183. Saadat E, Jobke B, Chu B, Lu Y, Cheng J, Li X, Ries MD, Majumdar S, Link T. Diagnostic performance of in vivo 3-T MRI for articular cartilage abnormalities in human osteoarthritic knees using histology as standard of reference. Eur Radiol. 2008 Oct; 18(10):2292-302. PMID: 18491096; PMCID: PMC2838768.
    184. Stahl R, Luke A, Ma CB, Krug R, Steinbach L, Majumdar S, Link T. Prevalence of pathologic findings in asymptomatic knees of marathon runners before and after a competition in comparison with physically active subjects-a 3.0 T magnetic resonance imaging study. Skeletal Radiol. 2008 Jul; 37(7):627-38. PMID: 18463868.
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    185. Huber MB, Carballido-Gamio J, Bauer JS, Baum T, Eckstein F, Lochmüller EM, Majumdar S, Link T. Proximal femur specimens: automated 3D trabecular bone mineral density analysis at multidetector CT--correlation with biomechanical strength measurement. Radiology. 2008 May; 247(2):472-81. PMID: 18430879.
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    186. Müller D, Bauer JS, Zeile M, Rummeny EJ, Link T. Significance of sagittal reformations in routine thoracic and abdominal multislice CT studies for detecting osteoporotic fractures and other spine abnormalities. Eur Radiol. 2008 Aug; 18(8):1696-702. PMID: 18418607.
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    187. Bolbos RI, Zuo J, Banerjee S, Link T, Ma CB, Li X, Majumdar S. Relationship between trabecular bone structure and articular cartilage morphology and relaxation times in early OA of the knee joint using parallel MRI at 3 T. Osteoarthritis Cartilage. 2008 Oct; 16(10):1150-9. PMID: 18387828; PMCID: PMC2580796.
    188. Krug R, Carballido-Gamio J, Banerjee S, Burghardt AJ, Link T, Majumdar S. In vivo ultra-high-field magnetic resonance imaging of trabecular bone microarchitecture at 7 T. J Magn Reson Imaging. 2008 Apr; 27(4):854-9. PMID: 18383263.
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    189. Kazakia GJ, Hyun B, Burghardt AJ, Krug R, Newitt DC, de Papp AE, Link T, Majumdar S. In vivo determination of bone structure in postmenopausal women: a comparison of HR-pQCT and high-field MR imaging. J Bone Miner Res. 2008 Apr; 23(4):463-74. PMID: 18052756.
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    190. Keshari KR, Lotz JC, Link T, Hu S, Majumdar S, Kurhanewicz J. Lactic acid and proteoglycans as metabolic markers for discogenic back pain. Spine (Phila Pa 1976). 2008 Feb 01; 33(3):312-7. PMID: 18303465.
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    191. Krug R, Carballido-Gamio J, Banerjee S, Stahl R, Carvajal L, Xu D, Vigneron D, Kelley DA, Link T, Majumdar S. In vivo bone and cartilage MRI using fully-balanced steady-state free-precession at 7 tesla. Magn Reson Med. 2007 Dec; 58(6):1294-8. PMID: 17957777.
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    192. Carballido-Gamio J, Bauer JS, Stahl R, Lee KY, Krause S, Link T, Majumdar S. Inter-subject comparison of MRI knee cartilage thickness. Med Image Anal. 2008 Apr; 12(2):120-35. PMID: 17923429; PMCID: PMC2838773.
    193. Patel PV, Eckstein F, Carballido-Gamio J, Phan C, Matsuura M, Lochmüller EM, Majumdar S, Link T. Fuzzy logic structure analysis of trabecular bone of the calcaneus to estimate proximal femur fracture load and discriminate subjects with and without vertebral fractures using high-resolution magnetic resonance imaging at 1.5 T and 3 T. Calcif Tissue Int. 2007 Oct; 81(4):294-304. PMID: 17705050.
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    194. Link T, de Mayo R, O'Donnell RJ. Radiofrequency ablation-an alternative for definitive treatment of solitary bone metastases. Eur Radiol. 2007 Nov; 17(11):3012-3. PMID: 17622538.
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    195. Bauer JS, Banerjee S, Henning TD, Krug R, Majumdar S, Link T. Fast high-spatial-resolution MRI of the ankle with parallel imaging using GRAPPA at 3 T. AJR Am J Roentgenol. 2007 Jul; 189(1):240-5. PMID: 17579177.
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    196. Bauer JS, Link T, Burghardt A, Henning TD, Mueller D, Majumdar S, Prevrhal S. Analysis of trabecular bone structure with multidetector spiral computed tomography in a simulated soft-tissue environment. Calcif Tissue Int. 2007 Jun; 80(6):366-73. PMID: 17520165.
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    197. Link T, Stahl R, Woertler K. Cartilage imaging: motivation, techniques, current and future significance. Eur Radiol. 2007 May; 17(5):1135-46. PMID: 17093967.
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    198. Bauer JS, Krause SJ, Ross CJ, Krug R, Carballido-Gamio J, Ozhinsky E, Majumdar S, Link T. Volumetric cartilage measurements of porcine knee at 1.5-T and 3.0-T MR imaging: evaluation of precision and accuracy. Radiology. 2006 Nov; 241(2):399-406. PMID: 17057067.
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    199. Barr C, Bauer JS, Malfair D, Ma B, Henning TD, Steinbach L, Link T. MR imaging of the ankle at 3 Tesla and 1.5 Tesla: protocol optimization and application to cartilage, ligament and tendon pathology in cadaver specimens. Eur Radiol. 2007 Jun; 17(6):1518-28. PMID: 17061070.
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    200. Daldrup-Link HE, Henning T, Link T. MR imaging of therapy-induced changes of bone marrow. Eur Radiol. 2007 Mar; 17(3):743-61. PMID: 17021706; PMCID: PMC1797072.
    201. Blumenkrantz G, Li X, Han ET, Newitt DC, Crane JC, Link T, Majumdar S. A feasibility study of in vivo T1rho imaging of the intervertebral disc. Magn Reson Imaging. 2006 Oct; 24(8):1001-7. PMID: 16997069.
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    202. Lozano J, Li X, Link T, Safran M, Majumdar S, Ma CB. Detection of posttraumatic cartilage injury using quantitative T1rho magnetic resonance imaging. A report of two cases with arthroscopic findings. J Bone Joint Surg Am. 2006 Jun; 88(6):1349-52. PMID: 16757771.
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    203. Carballido-Gamio J, Phan C, Link T, Majumdar S. Characterization of trabecular bone structure from high-resolution magnetic resonance images using fuzzy logic. Magn Reson Imaging. 2006 Oct; 24(8):1023-9. PMID: 16997072.
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    204. Phan CM, Matsuura M, Bauer JS, Dunn TC, Newitt D, Lochmueller EM, Eckstein F, Majumdar S, Link T. Trabecular bone structure of the calcaneus: comparison of MR imaging at 3.0 and 1.5 T with micro-CT as the standard of reference. Radiology. 2006 May; 239(2):488-96. PMID: 16569786.
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    205. Phan CM, Link T, Blumenkrantz G, Dunn TC, Ries MD, Steinbach LS, Majumdar S. MR imaging findings in the follow-up of patients with different stages of knee osteoarthritis and the correlation with clinical symptoms. Eur Radiol. 2006 Mar; 16(3):608-18. PMID: 16222533.
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    206. Li X, Han ET, Ma CB, Link T, Newitt DC, Majumdar S. In vivo 3T spiral imaging based multi-slice T(1rho) mapping of knee cartilage in osteoarthritis. Magn Reson Med. 2005 Oct; 54(4):929-36. PMID: 16155867.
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    207. Lee KY, Masi JN, Sell CA, Schier R, Link T, Steinbach LS, Safran M, Ma B, Majumdar S. Computer-aided quantification of focal cartilage lesions using MRI: accuracy and initial arthroscopic comparison. Osteoarthritis Cartilage. 2005 Aug; 13(8):728-37. PMID: 15908235.
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    208. Link T, Mischung J, Wörtler K, Burkart A, Rummeny EJ, Imhoff AB. Normal and pathological MR findings in osteochondral autografts with longitudinal follow-up. Eur Radiol. 2006 Jan; 16(1):88-96. PMID: 16021456.
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    209. Masi JN, Sell CA, Phan C, Han E, Newitt D, Steinbach L, Majumdar S, Link T. Cartilage MR imaging at 3.0 versus that at 1.5 T: preliminary results in a porcine model. Radiology. 2005 Jul; 236(1):140-50. PMID: 15987970.
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    210. Masi JN, Newitt D, Sell CA, Daldrup-Link H, Steinbach L, Majumdar S, Link T. Optimization of gadodiamide concentration for MR arthrography at 3 T. AJR Am J Roentgenol. 2005 Jun; 184(6):1754-61. PMID: 15908526.
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    211. Link T, Guglielmi G, van Kuijk C, Adams JE. Radiologic assessment of osteoporotic vertebral fractures: diagnostic and prognostic implications. Eur Radiol. 2005 Aug; 15(8):1521-32. PMID: 15841380.
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    212. Blumenkrantz G, Lindsey CT, Dunn TC, Jin H, Ries MD, Link T, Steinbach LS, Majumdar S. A pilot, two-year longitudinal study of the interrelationship between trabecular bone and articular cartilage in the osteoarthritic knee. Osteoarthritis Cartilage. 2004 Dec; 12(12):997-1005. PMID: 15564067.
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    213. Beer A, Saar B, Zantl N, Link T, Roggel R, Hwang SL, Schwaibold H, Rummeny EJ. MR cystography for bladder tumor detection. Eur Radiol. 2004 Dec; 14(12):2311-9. PMID: 15322808.
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    214. Link T, Majumdar S. Current diagnostic techniques in the evaluation of bone architecture. Curr Osteoporos Rep. 2004 Jun; 2(2):47-52. PMID: 16036082.
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    215. Brügel M, Link T, Rummeny EJ, Lange P, Theisen J, Dobritz M. Assessment of vascular invasion in pancreatic head cancer with multislice spiral CT: value of multiplanar reconstructions. Eur Radiol. 2004 Jul; 14(7):1188-95. PMID: 15083335.
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    216. Link T, Steinbach LS, Ghosh S, Ries M, Lu Y, Lane N, Majumdar S. Osteoarthritis: MR imaging findings in different stages of disease and correlation with clinical findings. Radiology. 2003 Feb; 226(2):373-81. PMID: 12563128.
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    217. Issever AS, Vieth V, Lotter A, Meier N, Laib A, Newitt D, Majumdar S, Link T. Local differences in the trabecular bone structure of the proximal femur depicted with high-spatial-resolution MR imaging and multisection CT. Acad Radiol. 2002 Dec; 9(12):1395-406. PMID: 12553351.
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    218. Link T, Vieth V, Stehling C, Lotter A, Beer A, Newitt D, Majumdar S. High-resolution MRI vs multislice spiral CT: which technique depicts the trabecular bone structure best? Eur Radiol. 2003 Apr; 13(4):663-71. PMID: 12664101.
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    219. Daldrup-Link HE, Rummeny EJ, Ihssen B, Kienast J, Link T. Iron-oxide-enhanced MR imaging of bone marrow in patients with non-Hodgkin's lymphoma: differentiation between tumor infiltration and hypercellular bone marrow. Eur Radiol. 2002 Jun; 12(6):1557-66. PMID: 12042968.
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    220. Beuf O, Ghosh S, Newitt DC, Link T, Steinbach L, Ries M, Lane N, Majumdar S. Magnetic resonance imaging of normal and osteoarthritic trabecular bone structure in the human knee. Arthritis Rheum. 2002 Feb; 46(2):385-93. PMID: 11840441.
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    221. Link T, Vieth V, Matheis J, Newitt D, Lu Y, Rummeny EJ, Majumdar S. Bone structure of the distal radius and the calcaneus vs BMD of the spine and proximal femur in the prediction of osteoporotic spine fractures. Eur Radiol. 2002 Feb; 12(2):401-8. PMID: 11870442.
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