Anat Levit, PhD

Title(s)RSCH GNT PRG OFCR 4, Quantitative_Bioscience_Ins
SchoolSchool of Pharmacy
Address1700 4th St
San Francisco CA 94158
Phone415-514-4253
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Structural identification of a hotspot on CFTR for potentiation. Science. 2019 06 21; 364(6446):1184-1188. Liu F, Zhang Z, Levit A, Levring J, Touhara KK, Shoichet BK, Chen J. PMID: 31221859; PMCID: PMC7184887.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    2. Ultra-large library docking for discovering new chemotypes. Nature. 2019 02; 566(7743):224-229. Lyu J, Wang S, Balius TE, Singh I, Levit A, Moroz YS, O'Meara MJ, Che T, Algaa E, Tolmachova K, Tolmachev AA, Shoichet BK, Roth BL, Irwin JJ. PMID: 30728502; PMCID: PMC6383769.
      View in: PubMed   Mentions: 97     Fields:    Translation:Humans
    3. Corrigendum: Independent Evolution of Strychnine Recognition by Bitter Taste Receptor Subtypes. Front Mol Biosci. 2018; 5:84. Xue AY, Di Pizio A, Levit A, Yarnitzky T, Penn O, Pupko T, Niv MY. PMID: 30255025; PMCID: PMC6142832.
      View in: PubMed   Mentions:
    4. The Recognition of Unrelated Ligands by Identical Proteins. ACS Chem Biol. 2018 09 21; 13(9):2522-2533. Pottel J, Levit A, Korczynska M, Fischer M, Shoichet BK. PMID: 30095890; PMCID: PMC6499068.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Reengineering the ligand sensitivity of the broadly tuned human bitter taste receptor TAS2R14. Biochim Biophys Acta Gen Subj. 2018 10; 1862(10):2162-2173. Nowak S, Di Pizio A, Levit A, Niv MY, Meyerhof W, Behrens M. PMID: 30009876.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    6. Independent Evolution of Strychnine Recognition by Bitter Taste Receptor Subtypes. Front Mol Biosci. 2018; 5:9. Xue AY, Di Pizio A, Levit A, Yarnitzky T, Penn O, Pupko T, Niv MY. PMID: 29552563; PMCID: PMC5840161.
      View in: PubMed   Mentions: 7  
    7. Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone. Nature. 2018 03 08; 555(7695):269-273. Wang S, Che T, Levit A, Shoichet BK, Wacker D, Roth BL. PMID: 29466326; PMCID: PMC5843546.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    8. D4 dopamine receptor high-resolution structures enable the discovery of selective agonists. Science. 2017 10 20; 358(6361):381-386. Wang S, Wacker D, Levit A, Che T, Betz RM, McCorvy JD, Venkatakrishnan AJ, Huang XP, Dror RO, Shoichet BK, Roth BL. PMID: 29051383; PMCID: PMC5856174.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    9. Crystal Structure of an LSD-Bound Human Serotonin Receptor. Cell. 2017 01 26; 168(3):377-389.e12. Wacker D, Wang S, McCorvy JD, Betz RM, Venkatakrishnan AJ, Levit A, Lansu K, Schools ZL, Che T, Nichols DE, Shoichet BK, Dror RO, Roth BL. PMID: 28129538; PMCID: PMC5289311.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansCells
    10. Structure-based discovery of opioid analgesics with reduced side effects. Nature. 2016 09 08; 537(7619):185-190. Manglik A, Lin H, Aryal DK, McCorvy JD, Dengler D, Corder G, Levit A, Kling RC, Bernat V, Hübner H, Huang XP, Sassano MF, Giguère PM, Löber S, Scherrer G, Kobilka BK, Gmeiner P, Roth BL, Shoichet BK. PMID: 27533032; PMCID: PMC5161585.
      View in: PubMed   Mentions: 220     Fields:    Translation:HumansAnimalsCells
    11. Comparing Class A GPCRs to bitter taste receptors: Structural motifs, ligand interactions and agonist-to-antagonist ratios. Methods Cell Biol. 2016; 132:401-27. Di Pizio A, Levit A, Slutzki M, Behrens M, Karaman R, Niv MY. PMID: 26928553.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    12. Predicting GPCR promiscuity using binding site features. J Chem Inf Model. 2014 Jan 27; 54(1):184-94. Levit A, Beuming T, Krilov G, Sherman W, Niv MY. PMID: 24328091.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    13. The bitter pill: clinical drugs that activate the human bitter taste receptor TAS2R14. FASEB J. 2014 Mar; 28(3):1181-97. Levit A, Nowak S, Peters M, Wiener A, Meyerhof W, Behrens M, Niv MY. PMID: 24285091.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    14. The human bitter taste receptor TAS2R10 is tailored to accommodate numerous diverse ligands. J Neurosci. 2013 Jan 02; 33(1):201-13. Born S, Levit A, Niv MY, Meyerhof W, Behrens M. PMID: 23283334; PMCID: PMC6618634.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    15. Expression and structure/function relationships of human defensin 5. Appl Biochem Biotechnol. 2012 Apr; 166(7):1703-10. Chapnik N, Levit A, Niv MY, Froy O. PMID: 22354633.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    16. Homology model-assisted elucidation of binding sites in GPCRs. Methods Mol Biol. 2012; 914:179-205. Levit A, Barak D, Behrens M, Meyerhof W, Niv MY. PMID: 22976029.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    17. Modeling of human prokineticin receptors: interactions with novel small-molecule binders and potential off-target drugs. PLoS One. 2011; 6(11):e27990. Levit A, Yarnitzky T, Wiener A, Meidan R, Niv MY. PMID: 22132188; PMCID: PMC3221691.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    18. BitterDB: a database of bitter compounds. Nucleic Acids Res. 2012 Jan; 40(Database issue):D413-9. Wiener A, Shudler M, Levit A, Niv MY. PMID: 21940398; PMCID: PMC3245057.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    19. Homology modeling of G-protein-coupled receptors with X-ray structures on the rise. Curr Opin Drug Discov Devel. 2010 May; 13(3):317-25. Yarnitzky T, Levit A, Niv MY. PMID: 20443165.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    20. Induction of endothelin-2 expression by luteinizing hormone and hypoxia: possible role in bovine corpus luteum formation. Endocrinology. 2010 Apr; 151(4):1914-22. Klipper E, Levit A, Mastich Y, Berisha B, Schams D, Meidan R. PMID: 20176726.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    21. Stargazin involvement with bipolar disorder and response to lithium treatment. Pharmacogenet Genomics. 2008 May; 18(5):403-12. Silberberg G, Levit A, Collier D, St Clair D, Munro J, Kerwin RW, Tondo L, Floris G, Breen G, Navon R. PMID: 18408563.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    22. A complete genetic association scan of the 22q11 deletion region and functional evidence reveal an association between DGCR2 and schizophrenia. Hum Genet. 2006 Sep; 120(2):160-70. Shifman S, Levit A, Chen ML, Chen CH, Bronstein M, Weizman A, Yakir B, Navon R, Darvasi A. PMID: 16783572.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
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