Anil Makam, MD, MAS

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
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    Collapse Biography 
    Collapse Education and Training
    Lehigh UniversityBS2003Biochemistry
    Drexel University College of MedicineMD2007Medicine
    UT SouthwesternResidency2010Internal Medicine
    UCSFFellowship2013Primary Care Research Fellowship
    UCSFMAS2013Clinical Research
    Collapse Awards and Honors
    Bay Area Clinical Research Symposium2012Best Oral Presentation by Jr. Investigator
    California-Hawaii Regional SGIM Annual Meeting2013Best Research Poster
    SGIM Annual Meeting2013Lipkin Award Finalist (not awarded)
    American Thoracic Society2016Behavioral Health & Health Services Research Abstract Scholarship
    UT Southwestern Medical Center; NIH/NCATS2014  - 2016KL2 Clinical and Translational Research Scholar
    NHLBI2014  - 2018NIH Loan Repayment Program Award
    SGIM Annual Meeting2014Hamolsky Junior Faculty Research Award Finalist (not awarded)
    Hopkins GIM Housestaff Research National Competition2017(mentor) Housestaff Research Award Honorable Mention
    Society of Hospital Medicine Annual Conference2018(mentor) Research, Innovation, Vignettes (RIV) Competition Honorable Mention in Innovation
    American Geriatrics Society2018New Investigator Award

    Collapse Overview 
    Collapse Overview
    Anil Makam, MD, MAS, is an academic hospital medicine physician and a health services researcher. His research is at the intersection of geriatrics, hospital medicine, and post-acute care, specifically focusing on the role of long-term acute care hospitals (LTACs). His research interest stemmed from his simple observation that Dallas had many LTACs whereas San Francisco had very few, yet he cared for similarly sick and frail hospitalized older adults in both places. His research is funded by an NIA GEMSSTAR grant (2016-2018) and an NIA K23 Career Development Award (2016-2021). Dr. Makam applies health services research and epidemiological methods using Medicare claims, EHR data, and prospective observational cohort data to examine predictors and variation in LTAC use, comparative effectiveness of the LTAC model of care versus alternative care settings, and patterns of recovery for older adults transferred to LTACs.

    Dr. Makam is also deeply passionate about evidence-based medicine and critical appraisal of the clinical scientific literature. He published his framework for the practice of EBM in a State-of-the-Art Review article in Circulation. He has also published a number of studies on EBM, high value care, and overuse of common medical practices. Prior to joining the faculty at UCSF, he has had extensive experience teaching EBM and critical appraisal to trainees and faculty.

    Dr. Makam’s research has been published in leading medical journals, including JAMA, JAMA Internal Medicine, Circulation, Journal of the American Geriatrics Society, BMJ Quality & Safety, Journal of General Internal Medicine, and the Journal of Hospital Medicine; has been cited by the Institute of Medicine and Wikipedia articles; and has been featured in prominent news outlets, including NPR. He has received several research awards, including the New Investigator Award in 2018 by the American Geriatrics Society. He is Co-Director of Academic Development & Research for the Division of Hospital Medicine at Chan Zuckerberg San Francisco General Hospital. Nationally, he is an Associate Editor for the Journal of Hospital Medicine. Lastly, he has an active presence on Twitter.

    Collapse Research 
    Collapse Research Activities and Funding
    Role of Long-Term Acute Care Hospitals
    NIH/NIA R03AG053291Aug 15, 2016 - Apr 30, 2018
    Role: Principal Investigator
    Post-Acute Care in the Elderly: the Role of Long-Term Acute Care Hospitals
    NIH/NIA K23AG052603Apr 1, 2016 - Mar 31, 2021
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse In The News
    Collapse Twitter

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Schumacher RC, Nguyen OK, Desphande K, Makam AN. Evidence-Based Medicine and the American Thoracic Society Clinical Practice Guidelines. JAMA Intern Med. 2019 Feb 18. PMID: 30776054.
      View in: PubMed
    2. Nguyen OK, Vazquez MA, Charles L, Berger JR, Quiñones H, Fuquay R, Sanders JM, Kapinos KA, Halm EA, Makam AN. Association of Scheduled vs Emergency-Only Dialysis With Health Outcomes and Costs in Undocumented Immigrants With End-stage Renal Disease. JAMA Intern Med. 2019 Feb 01; 179(2):175-183. PMID: 30575859.
      View in: PubMed
    3. Makam AN, Nguyen OK, Kirby B, Miller ME, Xuan L, Halm EA. Effect of Site-Neutral Payment Policy on Long-Term Acute Care Hospital Use. J Am Geriatr Soc. 2018 Nov; 66(11):2104-2111. PMID: 30281783.
      View in: PubMed
    4. Makam AN, Nguyen OK, Xuan L, Miller ME, Halm EA. Long-Term Acute Care Hospital Use of Non-Mechanically Ventilated Hospitalized Older Adults. J Am Geriatr Soc. 2018 Nov; 66(11):2112-2119. PMID: 30295927.
      View in: PubMed
    5. Makam AN, Nguyen OK, Halm EA. Shortcomings of Research Regarding Long-term Acute Care Hospitals and Skilled Nursing Facilities-Reply. JAMA Intern Med. 2018 Jun 01; 178(6):866-867. PMID: 29868749.
      View in: PubMed
    6. Nguyen OK, Makam AN, Clark C, Zhang S, Das SR, Halm EA. Predicting 30-Day Hospital Readmissions in Acute Myocardial Infarction: The AMI "READMITS" (Renal Function, Elevated Brain Natriuretic Peptide, Age, Diabetes Mellitus, Nonmale Sex, Intervention with Timely Percutaneous Coronary Intervention, and Low Systolic Blood Pressure) Score. J Am Heart Assoc. 2018 Apr 17; 7(8). PMID: 29666065.
      View in: PubMed
    7. Nguyen OK, Higashi RT, Makam AN, Mijares JC, Lee SC. The Influence of Financial Strain on Health Decision-Making. J Gen Intern Med. 2018 04; 33(4):406-408. PMID: 29340939.
      View in: PubMed
    8. Makam AN, Nguyen OK, Xuan L, Miller ME, Goodwin JS, Halm EA. Factors Associated With Variation in Long-term Acute Care Hospital vs Skilled Nursing Facility Use Among Hospitalized Older Adults. JAMA Intern Med. 2018 Mar 01; 178(3):399-405. PMID: 29404575.
      View in: PubMed
    9. Smith LN, Makam AN, Darden D, Mayo H, Das SR, Halm EA, Nguyen OK. Acute Myocardial Infarction Readmission Risk Prediction Models: A Systematic Review of Model Performance. Circ Cardiovasc Qual Outcomes. 2018 Jan; 11(1):e003885. PMID: 29321135.
      View in: PubMed
    10. Chaulk AL, Wang JI, Makam AN. A Depressing Diagnostic Error. Am J Med. 2018 May; 131(5):e191-e192. PMID: 29284114.
      View in: PubMed
    11. Nguyen OK, Makam AN. What Are the Opportunity Costs of Self-Financing Medical Education? Acad Med. 2017 Dec; 92(12):1655. PMID: 29210740.
      View in: PubMed
    12. Keshvani N, Berger K, Nguyen OK, Makam AN. Roadmap for improving the accuracy of respiratory rate measurements. BMJ Qual Saf. 2018 Aug; 27(8):e5. PMID: 29122976.
      View in: PubMed
    13. Badawy J, Nguyen OK, Clark C, Halm EA, Makam AN. Is everyone really breathing 20 times a minute? Assessing epidemiology and variation in recorded respiratory rate in hospitalised adults. BMJ Qual Saf. 2017 Oct; 26(10):832-836. PMID: 28652259.
      View in: PubMed
    14. Makam AN, Nguyen OK, Clark C, Halm EA. Incidence, Predictors, and Outcomes of Hospital-Acquired Anemia. J Hosp Med. 2017 05; 12(5):317-322. PMID: 28459899.
      View in: PubMed
    15. Makam AN, Nguyen OK, Clark C, Zhang S, Xie B, Weinreich M, Mortensen EM, Halm EA. Predicting 30-Day Pneumonia Readmissions Using Electronic Health Record Data. J Hosp Med. 2017 04; 12(4):209-216. PMID: 28411288.
      View in: PubMed
    16. Makam AN, Nguyen OK. An Evidence-Based Medicine Approach to Antihyperglycemic Therapy in Diabetes Mellitus to Overcome Overtreatment. Circulation. 2017 Jan 10; 135(2):180-195. PMID: 28069712.
      View in: PubMed
    17. Weinreich M, Nguyen OK, Wang D, Mayo H, Mortensen EM, Halm EA, Makam AN. Predicting the Risk of Readmission in Pneumonia. A Systematic Review of Model Performance. Ann Am Thorac Soc. 2016 09; 13(9):1607-14. PMID: 27299853.
      View in: PubMed
    18. Nguyen OK, Makam AN, Clark C, Zhang S, Xie B, Velasco F, Amarasingham R, Halm EA. Vital Signs Are Still Vital: Instability on Discharge and the Risk of Post-Discharge Adverse Outcomes. J Gen Intern Med. 2017 01; 32(1):42-48. PMID: 27503438.
      View in: PubMed
    19. Nguyen OK, Halm EA, Makam AN. Further Limitations of the HOSPITAL Score in US Hospitals. JAMA Intern Med. 2016 08 01; 176(8):1232-3. PMID: 27479675.
      View in: PubMed
    20. Makam AN, Nguyen OK. Clinical Criteria to Identify Patients With Sepsis. JAMA. 2016 Jul 26; 316(4):453. PMID: 27458952.
      View in: PubMed
    21. Nguyen OK, Makam AN, Halm EA. National Use of Safety-Net Clinics for Primary Care among Adults with Non-Medicaid Insurance in the United States. PLoS One. 2016; 11(3):e0151610. PMID: 27027617; PMCID: PMC4814117.
    22. Nguyen OK, Makam AN, Clark C, Zhang S, Xie B, Velasco F, Amarasingham R, Halm EA. Predicting all-cause readmissions using electronic health record data from the entire hospitalization: Model development and comparison. J Hosp Med. 2016 07; 11(7):473-80. PMID: 26929062.
      View in: PubMed
    23. Nguyen OK, Halm EA, Makam AN. Relationship between hospital financial performance and publicly reported outcomes. J Hosp Med. 2016 07; 11(7):481-8. PMID: 26929094.
      View in: PubMed
    24. Makam AN, Nguyen OK, Zhou J, Ottenbacher KJ, Halm EA. Trends in Long-Term Acute Care Hospital Use in Texas from 2002-2011. Ann Gerontol Geriatr Res. 2015; 2(3). PMID: 26702452.
      View in: PubMed
    25. Nguyen LT, Sullivan CT, Makam AN. The Diagnostic Cascade of Incidental Findings: A Teachable Moment. JAMA Intern Med. 2015 Jul; 175(7):1089-90. PMID: 25938592.
      View in: PubMed
    26. Makam AN, Steinman MA. Response to Einhorn and colleagues. J Am Geriatr Soc. 2015 May; 63(5):1047-8. PMID: 25989580.
      View in: PubMed
    27. Makam AN, Nguyen OK, Auerbach AD. Diagnostic accuracy and effectiveness of automated electronic sepsis alert systems: A systematic review. J Hosp Med. 2015 Jun; 10(6):396-402. PMID: 25758641; PMCID: PMC4477829.
    28. Makam AN, Nguyen OK. Use of cardiac biomarker testing in the emergency department. JAMA Intern Med. 2015 Jan; 175(1):67-75. PMID: 25401720.
      View in: PubMed
    29. Nguyen OK, Chan CV, Makam A, Stieglitz H, Amarasingham R. Envisioning a social-health information exchange as a platform to support a patient-centered medical neighborhood: a feasibility study. J Gen Intern Med. 2015 Jan; 30(1):60-7. PMID: 25092009; PMCID: PMC4284262.
    30. Makam AN, Boscardin WJ, Miao Y, Steinman MA. Risk of thiazide-induced metabolic adverse events in older adults. J Am Geriatr Soc. 2014 Jun; 62(6):1039-45. PMID: 24823661; PMCID: PMC4128471.
    31. Makam AN, Auerbach AD, Steinman MA. Blood culture use in the emergency department in patients hospitalized for community-acquired pneumonia. JAMA Intern Med. 2014 May; 174(5):803-6. PMID: 24614986; PMCID: PMC4123670.
    32. Makam AN, Auerbach AD, Steinman MA. Blood culture use in the emergency department in patients hospitalized with respiratory symptoms due to a nonpneumonia illness. J Hosp Med. 2014 Aug; 9(8):521-4. PMID: 24753399; PMCID: PMC4128469.
    33. Oresanya L, Makam AN, Belkin M, Moneta GL, Conte MS. Factors associated with primary vein graft occlusion in a multicenter trial with mandated ultrasound surveillance. J Vasc Surg. 2014 Apr; 59(4):996-1002. PMID: 24361199.
      View in: PubMed
    34. Makam AN, Lanham HJ, Batchelor K, Moran B, Howell-Stampley T, Kirk L, Cherukuri M, Samal L, Santini N, Leykum LK, Halm EA. The good, the bad and the early adopters: providers' attitudes about a common, commercial EHR. J Eval Clin Pract. 2014 Feb; 20(1):36-42. PMID: 23962319.
      View in: PubMed
    35. Makam AN, Lanham HJ, Batchelor K, Samal L, Moran B, Howell-Stampley T, Kirk L, Cherukuri M, Santini N, Leykum LK, Halm EA. Use and satisfaction with key functions of a common commercial electronic health record: a survey of primary care providers. BMC Med Inform Decis Mak. 2013 Aug 09; 13:86. PMID: 24070335; PMCID: PMC3750656.
    36. Makam AN, Nguyen OK, Moore B, Ma Y, Amarasingham R. Identifying patients with diabetes and the earliest date of diagnosis in real time: an electronic health record case-finding algorithm. BMC Med Inform Decis Mak. 2013 Aug 01; 13:81. PMID: 23915139; PMCID: PMC3733983.