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Bin Liu, PhD

Title(s)Professor, Anesthesia
SchoolSchool of Medicine
Address1001 Potrero Ave
San Francisco CA 94110
Phone628-206-3251
ORCID ORCID Icon0000-0002-5836-2333 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPostdoctoral StudiesGraduate Division

    Collapse Research 
    Collapse Research Activities and Funding
    Novel radioimmunoconjugates for targeted alpha-particle therapy of metastatic prostatic cancer
    NIH/NCI R01CA223767Jun 1, 2018 - May 31, 2023
    Role: Co-Principal Investigator
    Internalizing human antibody-targeted nanosized siRNA therapeutics
    NIH/NCI R01CA171315Aug 6, 2012 - Jul 31, 2017
    Role: Principal Investigator
    Identifying antigens bound by novel scFvs targeting all subtypes of mesothelioma
    NIH/NCI R01CA129491Mar 1, 2010 - Dec 31, 2014
    Role: Principal Investigator
    Selection of internalizing human antibodies targeting pancreatic tumor cells in s
    NIH/NCI R21CA137429Feb 1, 2009 - Jan 31, 2012
    Role: Principal Investigator
    Internalizing antibody-targeted nanosized siRNA therapeutics
    NIH/NCI R21CA135586Dec 5, 2008 - Nov 30, 2011
    Role: Principal Investigator
    Mapping a clinically significant internalizing tumor epitope space
    NIH/NCI R01CA118919Mar 7, 2006 - May 31, 2011
    Role: Principal Investigator
    Tumor specific cell sruface epitope- molecular evolution
    NIH/NIDDK R21DK066429Feb 1, 2004 - Jan 31, 2007
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Methods for site-specific drug conjugation to antibodies. MAbs. 2014 Jan-Feb; 6(1):46-53. Behrens CR, Liu B. PMID: 24135651.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimals
    2. Enhanced growth inhibition of osteosarcoma by cytotoxic polymerized liposomal nanoparticles targeting the alcam cell surface receptor. Sarcoma. 2012; 2012:126906. Federman N, Chan J, Nagy JO, Landaw EM, McCabe K, Wu AM, Triche T, Kang H, Liu B, Marks JD, Denny CT. PMID: 23024593.
      View in: PubMed   Mentions:
    3. An engineered cysteine-modified diabody for imaging activated leukocyte cell adhesion molecule (ALCAM)-positive tumors. Mol Imaging Biol. 2012 Jun; 14(3):336-47. McCabe KE, Liu B, Marks JD, Tomlinson JS, Wu H, Wu AM. PMID: 21630083.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    4. Novel human single chain antibody fragments that are rapidly internalizing effectively target epithelioid and sarcomatoid mesotheliomas. Cancer Res. 2011 Apr 01; 71(7):2428-32. Iyer AK, Lan X, Zhu X, Su Y, Feng J, Zhang X, Gao D, Seo Y, Vanbrocklin HF, Broaddus VC, Liu B, He J. PMID: 21447742.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    5. The effect of internalizing human single chain antibody fragment on liposome targeting to epithelioid and sarcomatoid mesothelioma. Biomaterials. 2011 Apr; 32(10):2605-13. Iyer AK, Su Y, Feng J, Lan X, Zhu X, Liu Y, Gao D, Seo Y, Vanbrocklin HF, Courtney Broaddus V, Liu B, He J. PMID: 21255833.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    6. Construction of yeast surface-displayed cDNA libraries. Methods Mol Biol. 2011; 729:199-210. Bidlingmaier S, Liu B. PMID: 21365492.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    7. Identification of protein/target molecule interactions using yeast surface-displayed cDNA libraries. Methods Mol Biol. 2011; 729:211-23. Bidlingmaier S, Liu B. PMID: 21365493.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    8. Comprehensive analysis of yeast surface displayed cDNA library selection outputs by exon microarray to identify novel protein-ligand interactions. Mol Cell Proteomics. 2011 Mar; 10(3):M110.005116. Bidlingmaier S, Wang Y, Liu Y, Zhang N, Liu B. PMID: 21127146.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    9. Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy. Mol Ther. 2010 Sep; 18(9):1650-6. Chen Y, Zhu X, Zhang X, Liu B, Huang L. PMID: 20606648.
      View in: PubMed   Mentions: 154     Fields:    Translation:HumansAnimalsCells
    10. Development of a highly stable and targetable nanoliposomal formulation of topotecan. J Control Release. 2010 Jan 04; 141(1):13-21. Drummond DC, Noble CO, Guo Z, Hayes ME, Connolly-Ingram C, Gabriel BS, Hann B, Liu B, Park JW, Hong K, Benz CC, Marks JD, Kirpotin DB. PMID: 19686789.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    11. Identification of MCAM/CD146 as the target antigen of a human monoclonal antibody that recognizes both epithelioid and sarcomatoid types of mesothelioma. Cancer Res. 2009 Feb 15; 69(4):1570-7. Bidlingmaier S, He J, Wang Y, An F, Feng J, Barbone D, Gao D, Franc B, Broaddus VC, Liu B. PMID: 19221091.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    12. Identification and characterization of tumor antigens by using antibody phage display and intrabody strategies. Mol Immunol. 2007 Jul; 44(15):3777-88. Goenaga AL, Zhou Y, Legay C, Bougherara H, Huang L, Liu B, Drummond DC, Kirpotin DB, Auclair C, Marks JD, Poul MA. PMID: 17498801.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    13. Applying phage antibodies to proteomics: selecting single chain Fv antibodies to antigens blotted on nitrocellulose. Anal Biochem. 2000 Nov 01; 286(1):119-28. Liu B, Marks JD. PMID: 11038282.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    14. Head-on collision between a DNA replication apparatus and RNA polymerase transcription complex. Science. 1995 Feb 24; 267(5201):1131-7. Liu B, Alberts BM. PMID: 7855590.
      View in: PubMed   Mentions: 82     Fields:    Translation:Cells
    15. A transcribing RNA polymerase molecule survives DNA replication without aborting its growing RNA chain. Proc Natl Acad Sci U S A. 1994 Oct 25; 91(22):10660-4. Liu B, Wong ML, Alberts B. PMID: 7524099.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    16. The DNA replication fork can pass RNA polymerase without displacing the nascent transcript. Nature. 1993 Nov 04; 366(6450):33-9. Liu B, Wong ML, Tinker RL, Geiduschek EP, Alberts BM. PMID: 8232535.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
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