James Marks, MD, PhD

Title(s)Professor, Anesthesia
SchoolSchool of Medicine
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Francisco Residency School of Medicine
    University of California, San FranciscoM.D.1979 School of Medicine

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Antibody Research Technology Center
    NIH P41CA196276Sep 24, 2014 - Aug 31, 2019
    Role: Principal Investigator
    Generation of therapeutic antibodies to serotype F botulism
    NIH R01AI104579Feb 1, 2013 - Jan 31, 2019
    Role: Principal Investigator
    Trispecific monoclonal antibody for botulinum neurotoxin intoxication therapy
    NIH R33AI101539Jun 20, 2012 - May 31, 2018
    Role: Principal Investigator
    Trispecific monoclonal antibody for botulinum neurotoxin intoxication therapy
    NIH R21AI101539Jun 1, 2012 - May 31, 2014
    Role: Principal Investigator
    Development of botulinum neurotoxin immunotherapy, serotypes C, D, F, and G
    NIH U01AI075443Aug 15, 2007 - Jul 31, 2013
    Role: Principal Investigator
    Pacific Southwest RCE for Biodefense & Emerging Infectious Diseases Research
    NIH U54AI065359May 20, 2005 - Apr 30, 2015
    Role: Co-Investigator
    Development of botulinum neurotoxin immunotherapy
    NIH U01AI056493Jul 15, 2003 - Dec 31, 2008
    Role: Principal Investigator
    Deciphering toxin neutralization by oligoclonal antibody
    NIH R21AI053389Sep 1, 2002 - Aug 31, 2005
    Role: Principal Investigator
    Mechanism-Based Evaluations of ErbB-Targeted Agents
    NIH U54CA090788Sep 26, 2001 - Dec 31, 2008
    Role: Co-Investigator
    Bio-Organic Biomedical Mass Spectrometry Resource
    NIH P41RR001614Mar 1, 1982 - May 31, 2015
    Role: Co-Investigator

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    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Predictors of All-Cause 30-Day Readmissions in Patients with Heart Failure at an Urban Safety Net Hospital: The Importance of Social Determinants of Health and Mental Health. Am J Med Open. 2023 Dec; 10:100060. Steverson AB, Marano PJ, Chen C, Ma Y, Stern RJ, Feng J, Gennatas ED, Marks JD, Durstenfeld MS, Davis JD, Hsue PY, Zier LS. PMID: 39035237; PMCID: PMC11256223.
      View in: PubMed   Mentions:
    2. San Francisco's Citywide COVID-19 Response: Strategies to Reduce COVID-19 Severity and Health Disparities, March 2020 Through May 2022. Public Health Rep. 2023 Sep-Oct; 138(5):747-755. Sachdev DD, Petersen M, Havlir DV, Schwab J, Enanoria WTA, Nguyen TQ, Mercer MP, Scheer S, Bennett A, Tenner AG, Marks JD, Bobba N, Philip S, Colfax G. PMID: 37408322; PMCID: PMC10323495.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    3. A Three-Monoclonal Antibody Combination Potently Neutralizes BoNT/G Toxin in Mice. Toxins (Basel). 2023 04 30; 15(5). Fan Y, Lou J, Tam CC, Wen W, Conrad F, Leal da Silva Alves P, Cheng LW, Garcia-Rodriguez C, Farr-Jones S, Marks JD. PMID: 37235351; PMCID: PMC10222606.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    4. Multicolor fluorescence activated cell sorting to generate humanized monoclonal antibody binding seven subtypes of BoNT/F. PLoS One. 2022; 17(9):e0273512. Fan Y, Sun Z, Conrad F, Wen W, Zhao L, Lou J, Zhou Y, Farr-Jones S, Marks JD. PMID: 36048906; PMCID: PMC9436041.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    5. Neutralizing Concentrations of Anti-Botulinum Toxin Antibodies Positively Correlate with Mouse Neutralization Assay Results in a Guinea Pig Model. Toxins (Basel). 2021 09 21; 13(9). Tomic MT, Farr-Jones S, Syar ES, Niemuth N, Kobs D, Hackett MJ, Espinoza Y, Martinez Z, Pham K, Snow DM, Marks JD, Cobb RR. PMID: 34564675; PMCID: PMC8471557.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    6. A Four-Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotypes C and D. Toxins (Basel). 2021 09 10; 13(9). Garcia-Rodriguez C, Yan S, Geren IN, Knopp KA, Dong J, Sun Z, Lou J, Conrad F, Wen WH, Farr-Jones S, Smith TJ, Brown JL, Skerry JC, Smith LA, Marks JD. PMID: 34564645; PMCID: PMC8472335.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    7. A Monoclonal Antibody Combination against both Serotypes A and B Botulinum Toxin Prevents Inhalational Botulism in a Guinea Pig Model. Toxins (Basel). 2021 01 05; 13(1). Snow DM, Cobb RR, Martinez J, Finger-Baker I, Collins L, Terpening S, Syar ES, Niemuth N, Kobs D, Barnewall R, Farr-Jones S, Marks JD, Tomic MT. PMID: 33466411; PMCID: PMC7824882.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    8. Targeting EphA2 in Bladder Cancer Using a Novel Antibody-Directed Nanotherapeutic. Pharmaceutics. 2020 Oct 20; 12(10). Kamoun W, Swindell E, Pien C, Luus L, Cain J, Pham M, Kandela I, Huang ZR, Tipparaju SK, Koshkaryev A, Askoxylakis V, Kirpotin DB, Bloom T, Mino-Kenudson M, Marks JD, Zalutskaya A, Bshara W, Morrison C, Drummond DC. PMID: 33092175; PMCID: PMC7589819.
      View in: PubMed   Mentions: 3  
    9. Cryo-EM Reveals Integrin-Mediated TGF-β Activation without Release from Latent TGF-β. Cell. 2020 02 06; 180(3):490-501.e16. Campbell MG, Cormier A, Ito S, Seed RI, Bondesson AJ, Lou J, Marks JD, Baron JL, Cheng Y, Nishimura SL. PMID: 31955848; PMCID: PMC7238552.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    10. The Novel Clostridial Neurotoxin Produced by Strain IBCA10-7060 Is Immunologically Equivalent to BoNT/HA. Toxins (Basel). 2019 12 20; 12(1). Fan Y, Barash JR, Conrad F, Lou J, Tam C, Cheng LW, Arnon SS, Marks JD. PMID: 31877649; PMCID: PMC7020490.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCellsPHPublic Health
    11. Antibody-mediated targeting of TNFR2 activates CD8+ T cells in mice and promotes antitumor immunity. Sci Transl Med. 2019 10 02; 11(512). Tam EM, Fulton RB, Sampson JF, Muda M, Camblin A, Richards J, Koshkaryev A, Tang J, Kurella V, Jiao Y, Xu L, Zhang K, Kohli N, Luus L, Hutto E, Kumar S, Lulo J, Paragas V, Wong C, Suchy J, Grabow S, Dugast AS, Zhang H, Depis F, Feau S, Jakubowski A, Qiao W, Craig G, Razlog M, Qiu J, Zhou Y, Marks JD, Croft M, Drummond DC, Raue A. PMID: 31578241.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    12. Safety and Pharmacokinetics of a Four Monoclonal Antibody Combination Against Botulinum C and D Neurotoxins. Antimicrob Agents Chemother. 2019 09 09; 63(12). Snow DM, Riling K, Kimbler A, Espinoza Y, Wong D, Pham K, Martinez Z, Kraus CN, Conrad F, Garcia-Rodriguez C, Cobb RR, Marks JD, Tomic MT. PMID: 31591130; PMCID: PMC6879217.
      View in: PubMed   Mentions: 15     Fields:    
    13. Pharmacokinetics of Human Recombinant Anti-Botulinum Toxin Antibodies in Rats. Toxins (Basel). 2019 06 17; 11(6). Espinoza Y, Wong D, Ahene A, Der K, Martinez Z, Pham J, Cobb RR, Farr-Jones S, Marks JD, Tomic MT. PMID: 31212950; PMCID: PMC6628388.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    14. Monoclonal Antibody Combinations Prevent Serotype A and Serotype B Inhalational Botulism in a Guinea Pig Model. Toxins (Basel). 2019 04 06; 11(4). Tomic MT, Espinoza Y, Martinez Z, Pham K, Cobb RR, Snow DM, Earnhart CG, Pals T, Syar ES, Niemuth N, Kobs DJ, Farr-Jones S, Marks JD. PMID: 30959899; PMCID: PMC6520708.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    15. Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse models. Nat Biomed Eng. 2019 04; 3(4):264-280. Kamoun WS, Kirpotin DB, Huang ZR, Tipparaju SK, Noble CO, Hayes ME, Luus L, Koshkaryev A, Kim J, Olivier K, Kornaga T, Oyama S, Askoxylakis V, Pien C, Kuesters G, Dumont N, Lugovskoy AA, Schihl SA, Wilton JH, Geddie ML, Suchy J, Grabow S, Kohli N, Reynolds CP, Blaydes R, Zhou Y, Sawyer AJ, Marks JD, Drummond DC. PMID: 30952988.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    16. Botulinum Neurotoxins (BoNTs)-Antibody and Vaccine. Toxins (Basel). 2018 11 26; 10(12). Lou J, Marks JD. PMID: 30486254; PMCID: PMC6315911.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    17. Integrin αvβ8-expressing tumor cells evade host immunity by regulating TGF-β activation in immune cells. JCI Insight. 2018 10 18; 3(20). Takasaka N, Seed RI, Cormier A, Bondesson AJ, Lou J, Elattma A, Ito S, Yanagisawa H, Hashimoto M, Ma R, Levine MD, Publicover J, Potts R, Jespersen JM, Campbell MG, Conrad F, Marks JD, Cheng Y, Baron JL, Nishimura SL. PMID: 30333313; PMCID: PMC6237456.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    18. Antibody engineering to improve manufacturability. Protein Expr Purif. 2018 09; 149:75-83. Wijesuriya SD, Pongo E, Tomic M, Zhang F, Garcia-Rodriquez C, Conrad F, Farr-Jones S, Marks JD, Horwitz AH. PMID: 29655788.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    19. A Three Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotype E Subtypes. Toxins (Basel). 2018 03 01; 10(3). Garcia-Rodriguez C, Razai A, Geren IN, Lou J, Conrad F, Wen WH, Farr-Jones S, Smith TJ, Brown JL, Skerry JC, Smith LA, Marks JD. PMID: 29494481; PMCID: PMC5869393.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    20. A Single Tri-Epitopic Antibody Virtually Recapitulates the Potency of a Combination of Three Monoclonal Antibodies in Neutralization of Botulinum Neurotoxin Serotype A. Toxins (Basel). 2018 02 15; 10(2). Lou J, Wen W, Conrad F, Meng Q, Dong J, Sun Z, Garcia-Rodriguez C, Farr-Jones S, Cheng LW, Henderson TD, Brown JL, Smith TJ, Smith LA, Cormier A, Marks JD. PMID: 29462889; PMCID: PMC5848185.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    21. Discovery of internalizing antibodies to basal breast cancer cells. Protein Eng Des Sel. 2018 01 01; 31(1):17-28. Zhou Y, Zou H, Yau C, Zhao L, Hall SC, Drummond DC, Farr-Jones S, Park JW, Benz CC, Marks JD. PMID: 29301020; PMCID: PMC6283401.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    22. A three monoclonal antibody combination potently neutralizes multiple botulinum neurotoxin serotype F subtypes. PLoS One. 2017; 12(3):e0174187. Fan Y, Garcia-Rodriguez C, Lou J, Wen W, Conrad F, Zhai W, Smith TJ, Smith LA, Marks JD. PMID: 28323873; PMCID: PMC5360321.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCellsPHPublic Health
    23. Improving the developability of an anti-EphA2 single-chain variable fragment for nanoparticle targeting. MAbs. 2017 01; 9(1):58-67. Geddie ML, Kohli N, Kirpotin DB, Razlog M, Jiao Y, Kornaga T, Rennard R, Xu L, Schoerberl B, Marks JD, Drummond DC, Lugovskoy AA. PMID: 27854147; PMCID: PMC5240644.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    24. White Matter Injury and General Movements in High-Risk Preterm Infants. AJNR Am J Neuroradiol. 2017 Jan; 38(1):162-169. Peyton C, Yang E, Msall ME, Adde L, Støen R, Fjørtoft T, Bos AF, Einspieler C, Zhou Y, Schreiber MD, Marks JD, Drobyshevsky A. PMID: 27789448; PMCID: PMC7963672.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    25. Immunological Characterization and Neutralizing Ability of Monoclonal Antibodies Directed Against Botulinum Neurotoxin Type H. J Infect Dis. 2016 May 15; 213(10):1606-14. Fan Y, Barash JR, Lou J, Conrad F, Marks JD, Arnon SS. PMID: 26936913; PMCID: PMC4837907.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    26. Development and Implementation of Checklists for Routine Anesthesia Care: A Proposal for Improving Patient Safety. Anesth Analg. 2015 Oct; 121(4):1097-1103. Krombach JW, Marks JD, Dubowitz G, Radke OC. PMID: 26378706.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    27. Neutralization of KIT Oncogenic Signaling in Leukemia with Antibodies Targeting KIT Membrane Proximal Domain 5. Mol Cancer Ther. 2015 Nov; 14(11):2595-605. Le Gall M, Crépin R, Neiveyans M, Auclair C, Fan Y, Zhou Y, Marks JD, Pèlegrin A, Poul MA. PMID: 26358753; PMCID: PMC6013065.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    28. Monoclonal Antibodies that Inhibit the Proteolytic Activity of Botulinum Neurotoxin Serotype/B. Toxins (Basel). 2015 Aug 26; 7(9):3405-23. Fan Y, Dong J, Lou J, Wen W, Conrad F, Geren IN, Garcia-Rodriguez C, Smith TJ, Smith LA, Ho M, Pires-Alves M, Wilson BA, Marks JD. PMID: 26343720; PMCID: PMC4591640.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    29. Checklists and Other Cognitive Aids For Emergency And Routine Anesthesia Care-A Survey on the Perception of Anesthesia Providers From a Large Academic US Institution. Anesth Pain Med. 2015 Aug; 5(4):e26300. Krombach JW, Edwards WA, Marks JD, Radke OC. PMID: 26568921; PMCID: PMC4637151.
      View in: PubMed   Mentions: 7  
    30. Immunosuppressive human anti-CD83 monoclonal antibody depletion of activated dendritic cells in transplantation. Leukemia. 2016 Mar; 30(3):692-700. Seldon TA, Pryor R, Palkova A, Jones ML, Verma ND, Findova M, Braet K, Sheng Y, Fan Y, Zhou EY, Marks JD, Munro T, Mahler SM, Barnard RT, Fromm PD, Silveira PA, Elgundi Z, Ju X, Clark GJ, Bradstock KF, Munster DJ, Hart DN. PMID: 26286117.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    31. Monoclonal Antibodies Targeting the Alpha-Exosite of Botulinum Neurotoxin Serotype/A Inhibit Catalytic Activity. PLoS One. 2015; 10(8):e0135306. Fan Y, Geren IN, Dong J, Lou J, Wen W, Conrad F, Smith TJ, Smith LA, Ho M, Pires-Alves M, Wilson BA, Marks JD. PMID: 26275214; PMCID: PMC4537209.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    32. TGF-β-Dependent Dendritic Cell Chemokinesis in Murine Models of Airway Disease. J Immunol. 2015 Aug 01; 195(3):1182-90. Hashimoto M, Yanagisawa H, Minagawa S, Sen D, Ma R, Murray LA, Tsui P, Lou J, Marks JD, Baron JL, Krummel MF, Nishimura SL. PMID: 26109638; PMCID: PMC4506848.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    33. A fully human scFv phage display library for rapid antibody fragment reformatting. Protein Eng Des Sel. 2015 Oct; 28(10):307-16. Li K, Zettlitz KA, Lipianskaya J, Zhou Y, Marks JD, Mallick P, Reiter RE, Wu AM. PMID: 25991864; PMCID: PMC4607741.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    34. Transforming Growth Factor-β and Interleukin-1β Signaling Pathways Converge on the Chemokine CCL20 Promoter. J Biol Chem. 2015 Jun 05; 290(23):14717-28. Brand OJ, Somanath S, Moermans C, Yanagisawa H, Hashimoto M, Cambier S, Markovics J, Bondesson AJ, Hill A, Jablons D, Wolters P, Lou J, Marks JD, Baron JL, Nishimura SL. PMID: 25918170; PMCID: PMC4505537.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    35. Combining anti-ERBB3 antibodies specific for domain I and domain III enhances the anti-tumor activity over the individual monoclonal antibodies. PLoS One. 2014; 9(11):e112376. D'Souza JW, Reddy S, Goldsmith LE, Shchaveleva I, Marks JD, Litwin S, Robinson MK. PMID: 25386657; PMCID: PMC4227695.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    36. High throughput identification of monoclonal antibodies to membrane bound and secreted proteins using yeast and phage display. PLoS One. 2014; 9(10):e111339. Zhao L, Qu L, Zhou J, Sun Z, Zou H, Chen YY, Marks JD, Zhou Y. PMID: 25353955; PMCID: PMC4213037.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    37. Anti-MET immunoPET for non-small cell lung cancer using novel fully human antibody fragments. Mol Cancer Ther. 2014 Nov; 13(11):2607-17. Li K, Tavaré R, Zettlitz KA, Mumenthaler SM, Mallick P, Zhou Y, Marks JD, Wu AM. PMID: 25143449; PMCID: PMC4221648.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    38. Development of an ELISA microarray assay for the sensitive and simultaneous detection of ten biodefense toxins. Analyst. 2014 Oct 21; 139(20):5093-102. Jenko KL, Zhang Y, Kostenko Y, Fan Y, Garcia-Rodriguez C, Lou J, Marks JD, Varnum SM. PMID: 25112421; PMCID: PMC6540756.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    39. Enhanced immunoPET of ALCAM-positive colorectal carcinoma using site-specific ⁶⁴Cu-DOTA conjugation. Protein Eng Des Sel. 2014 Oct; 27(10):317-24. Tavaré R, Wu WH, Zettlitz KA, Salazar FB, McCabe KE, Marks JD, Wu AM. PMID: 25095796; PMCID: PMC4191443.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    40. Selective targeting of TGF-β activation to treat fibroinflammatory airway disease. Sci Transl Med. 2014 Jun 18; 6(241):241ra79. Minagawa S, Lou J, Seed RI, Cormier A, Wu S, Cheng Y, Murray L, Tsui P, Connor J, Herbst R, Govaerts C, Barker T, Cambier S, Yanagisawa H, Goodsell A, Hashimoto M, Brand OJ, Cheng R, Ma R, McKnelly KJ, Wen W, Hill A, Jablons D, Wolters P, Kitamura H, Araya J, Barczak AJ, Erle DJ, Reichardt LF, Marks JD, Baron JL, Nishimura SL. PMID: 24944194; PMCID: PMC4341974.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimals
    41. Identifying blood-brain-barrier selective single-chain antibody fragments. Biotechnol J. 2014 May; 9(5):664-74. Jones AR, Stutz CC, Zhou Y, Marks JD, Shusta EV. PMID: 24644233; PMCID: PMC4073886.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    42. Identification of the synaptic vesicle glycoprotein 2 receptor binding site in botulinum neurotoxin A. FEBS Lett. 2014 Apr 02; 588(7):1087-93. Strotmeier J, Mahrhold S, Krez N, Janzen C, Lou J, Marks JD, Binz T, Rummel A. PMID: 24583011; PMCID: PMC4067265.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    43. RNA aptasensor for rapid detection of natively folded type A botulinum neurotoxin. Talanta. 2013 Dec 15; 117:273-80. Janardhanan P, Mello CM, Singh BR, Lou J, Marks JD, Cai S. PMID: 24209341; PMCID: PMC3909959.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    44. Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E. Biochem J. 2013 Jul 01; 453(1):37-47. Mahrhold S, Strotmeier J, Garcia-Rodriguez C, Lou J, Marks JD, Rummel A, Binz T. PMID: 23621114.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    45. Use of a new functional dual coating (FDC) assay to measure low toxin levels in serum and food samples following an outbreak of human botulism. J Med Microbiol. 2013 Jun; 62(Pt 6):828-835. Jones RGA, Marks JD. PMID: 23518650.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    46. Enhanced growth inhibition of osteosarcoma by cytotoxic polymerized liposomal nanoparticles targeting the alcam cell surface receptor. Sarcoma. 2012; 2012:126906. Federman N, Chan J, Nagy JO, Landaw EM, McCabe K, Wu AM, Triche T, Kang H, Liu B, Marks JD, Denny CT. PMID: 23024593; PMCID: PMC3447386.
      View in: PubMed   Mentions: 22  
    47. Simultaneous and sensitive detection of six serotypes of botulinum neurotoxin using enzyme-linked immunosorbent assay-based protein antibody microarrays. Anal Biochem. 2012 Nov 15; 430(2):185-92. Zhang Y, Lou J, Jenko KL, Marks JD, Varnum SM. PMID: 22935296; PMCID: PMC3589981.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    48. Engineered domain-based assays to identify individual antibodies in oligoclonal combinations targeting the same protein. Anal Biochem. 2012 Nov 15; 430(2):141-50. Meng Q, Garcia-Rodriguez C, Manzanarez G, Silberg MA, Conrad F, Bettencourt J, Pan X, Breece T, To R, Li M, Lee D, Thorner L, Tomic MT, Marks JD. PMID: 22922799; PMCID: PMC4209713.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    49. N-Terminal labeling of filamentous phage to create cancer marker imaging agents. ACS Nano. 2012 Aug 28; 6(8):6675-80. Carrico ZM, Farkas ME, Zhou Y, Hsiao SC, Marks JD, Chokhawala H, Clark DS, Francis MB. PMID: 22830952; PMCID: PMC3435507.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    50. An engineered cysteine-modified diabody for imaging activated leukocyte cell adhesion molecule (ALCAM)-positive tumors. Mol Imaging Biol. 2012 Jun; 14(3):336-47. McCabe KE, Liu B, Marks JD, Tomlinson JS, Wu H, Wu AM. PMID: 21630083; PMCID: PMC3227780.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    51. Selection and characterization of cell binding and internalizing phage antibodies. Arch Biochem Biophys. 2012 Oct 15; 526(2):107-13. Zhou Y, Zhao L, Marks JD. PMID: 22627065; PMCID: PMC4209712.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    52. Impact of intrinsic affinity on functional binding and biological activity of EGFR antibodies. Mol Cancer Ther. 2012 Jul; 11(7):1467-76. Zhou Y, Goenaga AL, Harms BD, Zou H, Lou J, Conrad F, Adams GP, Schoeberl B, Nielsen UB, Marks JD. PMID: 22564724; PMCID: PMC4209485.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    53. A functional dual-coated (FDC) microtiter plate method to replace the botulinum toxin LD50 test. Anal Biochem. 2012 Jun 01; 425(1):28-35. Liu YY, Rigsby P, Sesardic D, Marks JD, Jones RG. PMID: 22406430.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    54. Building and characterizing antibody-targeted lipidic nanotherapeutics. Methods Enzymol. 2012; 502:139-66. Kirpotin DB, Noble CO, Hayes ME, Huang Z, Kornaga T, Zhou Y, Nielsen UB, Marks JD, Drummond DC. PMID: 22208985.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    55. Discovery of internalizing antibodies to tumor antigens from phage libraries. Methods Enzymol. 2012; 502:43-66. Zhou Y, Marks JD. PMID: 22208981; PMCID: PMC4180867.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    56. Single-chain antibody-based immunotoxins targeting Her2/neu: design optimization and impact of affinity on antitumor efficacy and off-target toxicity. Mol Cancer Ther. 2012 Jan; 11(1):143-53. Cao Y, Marks JD, Huang Q, Rudnick SI, Xiong C, Hittelman WN, Wen X, Marks JW, Cheung LH, Boland K, Li C, Adams GP, Rosenblum MG. PMID: 22090420.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    57. Extraction and inhibition of enzymatic activity of botulinum neurotoxins /B1, /B2, /B3, /B4, and /B5 by a panel of monoclonal anti-BoNT/B antibodies. BMC Biochem. 2011 Nov 15; 12:58. Kalb SR, Santana WI, Geren IN, Garcia-Rodriguez C, Lou J, Smith TJ, Marks JD, Smith LA, Pirkle JL, Barr JR. PMID: 22085466; PMCID: PMC3250939.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    58. Affinity maturation to improve human monoclonal antibody neutralization potency and breadth against hepatitis C virus. J Biol Chem. 2011 Dec 23; 286(51):44218-44233. Wang Y, Keck ZY, Saha A, Xia J, Conrad F, Lou J, Eckart M, Marks JD, Foung SKH. PMID: 22002064; PMCID: PMC3243554.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    59. Domain-based assays of individual antibody concentrations in an oligoclonal combination targeting a single protein. Anal Biochem. 2012 Feb 15; 421(2):351-61. Meng Q, Li M, Silberg MA, Conrad F, Bettencourt J, To R, Huang C, Ma J, Meyer K, Shimizu R, Cao L, Tomic MT, Marks JD. PMID: 22037290; PMCID: PMC4209596.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    60. Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β. J Clin Invest. 2011 Jul; 121(7):2863-75. Kitamura H, Cambier S, Somanath S, Barker T, Minagawa S, Markovics J, Goodsell A, Publicover J, Reichardt L, Jablons D, Wolters P, Hill A, Marks JD, Lou J, Pittet JF, Gauldie J, Baron JL, Nishimura SL. PMID: 21646718; PMCID: PMC3223836.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    61. Synergistic capture of Clostridium botulinum type A neurotoxin by scFv antibodies to novel epitopes. Biotechnol Bioeng. 2011 Oct; 108(10):2456-67. Gray SA, Barr JR, Kalb SR, Marks JD, Baird CL, Cangelosi GA, Miller KD, Feldhaus MJ. PMID: 21538339; PMCID: PMC3203252.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    62. Influence of affinity and antigen internalization on the uptake and penetration of Anti-HER2 antibodies in solid tumors. Cancer Res. 2011 Mar 15; 71(6):2250-9. Rudnick SI, Lou J, Shaller CC, Tang Y, Klein-Szanto AJ, Weiner LM, Marks JD, Adams GP. PMID: 21406401; PMCID: PMC3077882.
      View in: PubMed   Mentions: 147     Fields:    Translation:HumansAnimalsCells
    63. Evaluation of the anti-HER2 C6.5 diabody as a PET radiotracer to monitor HER2 status and predict response to trastuzumab treatment. Clin Cancer Res. 2011 Mar 15; 17(6):1509-20. Reddy S, Shaller CC, Doss M, Shchaveleva I, Marks JD, Yu JQ, Robinson MK. PMID: 21177408; PMCID: PMC3060271.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    64. Neutralizing human monoclonal antibodies binding multiple serotypes of botulinum neurotoxin. Protein Eng Des Sel. 2011 Mar; 24(3):321-31. Garcia-Rodriguez C, Geren IN, Lou J, Conrad F, Forsyth C, Wen W, Chakraborti S, Zao H, Manzanarez G, Smith TJ, Brown J, Tepp WH, Liu N, Wijesuriya S, Tomic MT, Johnson EA, Smith LA, Marks JD. PMID: 21149386; PMCID: PMC3038462.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    65. Internalizing cancer antibodies from phage libraries selected on tumor cells and yeast-displayed tumor antigens. J Mol Biol. 2010 Nov 19; 404(1):88-99. Zhou Y, Zou H, Zhang S, Marks JD. PMID: 20851130; PMCID: PMC4195448.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    66. Extraction of BoNT/A, /B, /E, and /F with a single, high affinity monoclonal antibody for detection of botulinum neurotoxin by Endopep-MS. PLoS One. 2010 Aug 17; 5(8):e12237. Kalb SR, Garcia-Rodriguez C, Lou J, Baudys J, Smith TJ, Marks JD, Smith LA, Pirkle JL, Barr JR. PMID: 20808925; PMCID: PMC2923190.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    67. TSG101 exposure on the surface of HIV-1 infected cells: implications for monoclonal antibody therapy for HIV/AIDS. Am J Transl Res. 2010 Jul 20; 2(4):368-80. Diaz L, Mao H, Zhou Y, Kohli M, Cassella J, Santos D, Fesseha Z, Weng K, Chen H, Bamba D, Marks JD, Goldblatt M, Kinch M. PMID: 20733947; PMCID: PMC2923861.
      View in: PubMed   Mentions: 2  
    68. Development of human single-chain antibodies to the transferrin receptor that effectively antagonize the growth of leukemias and lymphomas. Cancer Res. 2010 Jul 01; 70(13):5497-506. Crépin R, Goenaga AL, Jullienne B, Bougherara H, Legay C, Benihoud K, Marks JD, Poul MA. PMID: 20530676.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    69. An affinity matured minibody for PET imaging of prostate stem cell antigen (PSCA)-expressing tumors. Eur J Nucl Med Mol Imaging. 2010 Aug; 37(8):1529-38. Lepin EJ, Leyton JV, Zhou Y, Olafsen T, Salazar FB, McCabe KE, Hahm S, Marks JD, Reiter RE, Wu AM. PMID: 20354850; PMCID: PMC2903645.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    70. Affinity maturation of human botulinum neurotoxin antibodies by light chain shuffling via yeast mating. Protein Eng Des Sel. 2010 Apr; 23(4):311-9. Lou J, Geren I, Garcia-Rodriguez C, Forsyth CM, Wen W, Knopp K, Brown J, Smith T, Smith LA, Marks JD. PMID: 20156888; PMCID: PMC2841544.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    71. Tumor detection by imaging proteolytic activity. Cancer Res. 2010 Feb 15; 70(4):1505-12. Darragh MR, Schneider EL, Lou J, Phojanakong PJ, Farady CJ, Marks JD, Hann BC, Craik CS. PMID: 20145119; PMCID: PMC2823079.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    72. A single-domain llama antibody potently inhibits the enzymatic activity of botulinum neurotoxin by binding to the non-catalytic alpha-exosite binding region. J Mol Biol. 2010 Apr 09; 397(4):1106-18. Dong J, Thompson AA, Fan Y, Lou J, Conrad F, Ho M, Pires-Alves M, Wilson BA, Stevens RC, Marks JD. PMID: 20138889; PMCID: PMC2903050.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    73. Construction and characterization of novel, recombinant immunotoxins targeting the Her2/neu oncogene product: in vitro and in vivo studies. Cancer Res. 2009 Dec 01; 69(23):8987-95. Cao Y, Marks JD, Marks JW, Cheung LH, Kim S, Rosenblum MG. PMID: 19934334.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    74. Development of a highly stable and targetable nanoliposomal formulation of topotecan. J Control Release. 2010 Jan 04; 141(1):13-21. Drummond DC, Noble CO, Guo Z, Hayes ME, Connolly-Ingram C, Gabriel BS, Hann B, Liu B, Park JW, Hong K, Benz CC, Marks JD, Kirpotin DB. PMID: 19686789.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    75. Antibody protection against botulinum neurotoxin intoxication in mice. Infect Immun. 2009 Oct; 77(10):4305-13. Cheng LW, Stanker LH, Henderson TD, Lou J, Marks JD. PMID: 19651864; PMCID: PMC2747958.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    76. Rapid multiplexed flow cytometric assay for botulinum neurotoxin detection using an automated fluidic microbead-trapping flow cell for enhanced sensitivity. Anal Chem. 2009 Jul 15; 81(14):5783-93. Ozanich RM, Bruckner-Lea CJ, Warner MG, Miller K, Antolick KC, Marks JD, Lou J, Grate JW. PMID: 19530657.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    77. Quantum dot immunoassays in renewable surface column and 96-well plate formats for the fluorescence detection of botulinum neurotoxin using high-affinity antibodies. Biosens Bioelectron. 2009 Sep 15; 25(1):179-84. Warner MG, Grate JW, Tyler A, Ozanich RM, Miller KD, Lou J, Marks JD, Bruckner-Lea CJ. PMID: 19643593; PMCID: PMC2728038.
      View in: PubMed   Mentions: 10     Fields:    
    78. Extraction and inhibition of enzymatic activity of botulinum neurotoxins/A1, /A2, and /A3 by a panel of monoclonal anti-BoNT/A antibodies. PLoS One. 2009; 4(4):e5355. Kalb SR, Lou J, Garcia-Rodriguez C, Geren IN, Smith TJ, Moura H, Marks JD, Smith LA, Pirkle JL, Barr JR. PMID: 19399171; PMCID: PMC2670495.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    79. Renewable surface fluorescence sandwich immunoassay biosensor for rapid sensitive botulinum toxin detection in an automated fluidic format. Analyst. 2009 May; 134(5):987-96. Grate JW, Warner MG, Ozanich RM, Miller KD, Colburn HA, Dockendorff B, Antolick KC, Anheier NC, Lind MA, Lou J, Marks JD, Bruckner-Lea CJ. PMID: 19381395.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    80. Human antibodies targeting cell surface antigens overexpressed by the hormone refractory metastatic prostate cancer cells: ICAM-1 is a tumor antigen that mediates prostate cancer cell invasion. J Mol Med (Berl). 2009 May; 87(5):507-14. Conrad F, Zhu X, Zhang X, Chalkley RJ, Burlingame AL, Marks JD, Liu B. PMID: 19219419; PMCID: PMC2796542.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    81. Characterization of highly stable liposomal and immunoliposomal formulations of vincristine and vinblastine. Cancer Chemother Pharmacol. 2009 Sep; 64(4):741-51. Noble CO, Guo Z, Hayes ME, Marks JD, Park JW, Benz CC, Kirpotin DB, Drummond DC. PMID: 19184019; PMCID: PMC2717390.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    82. Therapeutic antibodies: current state and future trends--is a paradigm change coming soon? Methods Mol Biol. 2009; 525:1-27, xiii. Dimitrov DS, Marks JD. PMID: 19252861; PMCID: PMC3402212.
      View in: PubMed   Mentions: 57     Fields:    Translation:Humans
    83. Identification of target and function specific antibodies for effective drug delivery. Methods Mol Biol. 2009; 525:145-60, xv. Zhou Y, Marks JD. PMID: 19252832.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    84. Diabodies targeting epithelial membrane protein 2 reduce tumorigenicity of human endometrial cancer cell lines. Clin Cancer Res. 2008 Nov 15; 14(22):7367-77. Shimazaki K, Lepin EJ, Wei B, Nagy AK, Coulam CP, Mareninov S, Fu M, Wu AM, Marks JD, Braun J, Gordon LK, Wadehra M. PMID: 19010852; PMCID: PMC3109074.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    85. Targeting ErbB2 and ErbB3 with a bispecific single-chain Fv enhances targeting selectivity and induces a therapeutic effect in vitro. Br J Cancer. 2008 Nov 04; 99(9):1415-25. Robinson MK, Hodge KM, Horak E, Sundberg AL, Russeva M, Shaller CC, von Mehren M, Shchaveleva I, Simmons HH, Marks JD, Adams GP. PMID: 18841159; PMCID: PMC2576487.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    86. Development of human single-chain antibodies against SARS-associated coronavirus. Intervirology. 2008; 51(3):173-81. Leung KM, Feng DX, Lou J, Zhou Y, Fung KP, Waye MM, Tsui SK, Chan PK, Marks JD, Pang SF, Kan YW. PMID: 18724064; PMCID: PMC7179547.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    87. Effective treatment of established human breast tumor xenografts in immunodeficient mice with a single dose of the alpha-emitting radioisotope astatine-211 conjugated to anti-HER2/neu diabodies. Clin Cancer Res. 2008 Feb 01; 14(3):875-82. Robinson MK, Shaller C, Garmestani K, Plascjak PS, Hodge KM, Yuan QA, Marks JD, Waldmann TA, Brechbiel MW, Adams GP. PMID: 18245551; PMCID: PMC2643368.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    88. Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids. PLoS One. 2007 Dec 05; 2(12):e1271. Smith TJ, Hill KK, Foley BT, Detter JC, Munk AC, Bruce DC, Doggett NA, Smith LA, Marks JD, Xie G, Brettin TS. PMID: 18060065; PMCID: PMC2092393.
      View in: PubMed   Mentions: 79     Fields:    Translation:Cells
    89. Molecular architecture of botulinum neurotoxin E revealed by single particle electron microscopy. J Biol Chem. 2008 Feb 15; 283(7):3997-4003. Fischer A, Garcia-Rodriguez C, Geren I, Lou J, Marks JD, Nakagawa T, Montal M. PMID: 18032388.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    90. Redirected activity of human antitumor chimeric immune receptors is governed by antigen and receptor expression levels and affinity of interaction. J Immunother. 2007 Oct; 30(7):684-93. Turatti F, Figini M, Balladore E, Alberti P, Casalini P, Marks JD, Canevari S, Mezzanzanica D. PMID: 17893561.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    91. Anti-CD166 single chain antibody-mediated intracellular delivery of liposomal drugs to prostate cancer cells. Mol Cancer Ther. 2007 Oct; 6(10):2737-46. Roth A, Drummond DC, Conrad F, Hayes ME, Kirpotin DB, Benz CC, Marks JD, Liu B. PMID: 17938267.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    92. Affinity thresholds for membrane fusion triggering by viral glycoproteins. J Virol. 2007 Dec; 81(23):13149-57. Hasegawa K, Hu C, Nakamura T, Marks JD, Russell SJ, Peng KW. PMID: 17804513; PMCID: PMC2169077.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    93. Regulation of antibody-dependent cellular cytotoxicity by IgG intrinsic and apparent affinity for target antigen. J Immunol. 2007 Sep 01; 179(5):2815-23. Tang Y, Lou J, Alpaugh RK, Robinson MK, Marks JD, Weiner LM. PMID: 17709495.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    94. Recombinant full-length human IgG1s targeting hormone-refractory prostate cancer. J Mol Med (Berl). 2007 Oct; 85(10):1113-23. Liu B, Conrad F, Roth A, Drummond DC, Simko JP, Marks JD. PMID: 17554518.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    95. Identification and characterization of tumor antigens by using antibody phage display and intrabody strategies. Mol Immunol. 2007 Jul; 44(15):3777-88. Goenaga AL, Zhou Y, Legay C, Bougherara H, Huang L, Liu B, Drummond DC, Kirpotin DB, Auclair C, Marks JD, Poul MA. PMID: 17498801; PMCID: PMC2739904.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    96. Impact of single-chain Fv antibody fragment affinity on nanoparticle targeting of epidermal growth factor receptor-expressing tumor cells. J Mol Biol. 2007 Aug 24; 371(4):934-47. Zhou Y, Drummond DC, Zou H, Hayes ME, Adams GP, Kirpotin DB, Marks JD. PMID: 17602702; PMCID: PMC4198021.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    97. Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin. Nat Biotechnol. 2007 Jan; 25(1):107-16. Garcia-Rodriguez C, Levy R, Arndt JW, Forsyth CM, Razai A, Lou J, Geren I, Stevens RC, Marks JD. PMID: 17173035.
      View in: PubMed   Mentions: 88     Fields:    Translation:Cells
    98. Genetic diversity among Botulinum Neurotoxin-producing clostridial strains. J Bacteriol. 2007 Feb; 189(3):818-32. Hill KK, Smith TJ, Helma CH, Ticknor LO, Foley BT, Svensson RT, Brown JL, Johnson EA, Smith LA, Okinaka RT, Jackson PJ, Marks JD. PMID: 17114256; PMCID: PMC1797315.
      View in: PubMed   Mentions: 198     Fields:    Translation:Cells
    99. Increased target specificity of anti-HER2 genospheres by modification of surface charge and degree of PEGylation. Mol Pharm. 2006 Nov-Dec; 3(6):726-36. Hayes ME, Drummond DC, Hong K, Zheng WW, Khorosheva VA, Cohen JA, C O N, Park JW, Marks JD, Benz CC, Kirpotin DB. PMID: 17140260.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    100. Fine and domain-level epitope mapping of botulinum neurotoxin type A neutralizing antibodies by yeast surface display. J Mol Biol. 2007 Jan 05; 365(1):196-210. Levy R, Forsyth CM, LaPorte SL, Geren IN, Smith LA, Marks JD. PMID: 17059824; PMCID: PMC1994578.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    101. A novel assay for monitoring internalization of nanocarrier coupled antibodies. BMC Immunol. 2006 Oct 02; 7:24. Nielsen UB, Kirpotin DB, Pickering EM, Drummond DC, Marks JD. PMID: 17014727; PMCID: PMC1633733.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    102. Using phage display to select antibodies recognizing post-translational modifications independently of sequence context. Mol Cell Proteomics. 2006 Dec; 5(12):2350-63. Kehoe JW, Velappan N, Walbolt M, Rasmussen J, King D, Lou J, Knopp K, Pavlik P, Marks JD, Bertozzi CR, Bradbury AR. PMID: 16971384.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    103. A structural perspective of the sequence variability within botulinum neurotoxin subtypes A1-A4. J Mol Biol. 2006 Sep 29; 362(4):733-42. Arndt JW, Jacobson MJ, Abola EE, Forsyth CM, Tepp WH, Marks JD, Johnson EA, Stevens RC. PMID: 16938310.
      View in: PubMed   Mentions: 48     Fields:    Translation:Cells
    104. Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models. Cancer Res. 2006 Jul 01; 66(13):6732-40. Kirpotin DB, Drummond DC, Shao Y, Shalaby MR, Hong K, Nielsen UB, Marks JD, Benz CC, Park JW. PMID: 16818648.
      View in: PubMed   Mentions: 338     Fields:    Translation:HumansAnimals
    105. Enzyme-amplified protein microarray and a fluidic renewable surface fluorescence immunoassay for botulinum neurotoxin detection using high-affinity recombinant antibodies. Anal Chim Acta. 2006 Jun 16; 570(2):137-43. Varnum SM, Warner MG, Dockendorff B, Anheier NC, Lou J, Marks JD, Smith LA, Feldhaus MJ, Grate JW, Bruckner-Lea CJ. PMID: 17723391.
      View in: PubMed   Mentions: 12     Fields:    
    106. Assembly of nucleic acid-lipid nanoparticles from aqueous-organic monophases. Biochim Biophys Acta. 2006 Apr; 1758(4):429-42. Hayes ME, Drummond DC, Hong K, Park JW, Marks JD, Kirpotin DB. PMID: 16678786.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    107. Genospheres: self-assembling nucleic acid-lipid nanoparticles suitable for targeted gene delivery. Gene Ther. 2006 Apr; 13(7):646-51. Hayes ME, Drummond DC, Kirpotin DB, Zheng WW, Noble CO, Park JW, Marks JD, Benz CC, Hong K. PMID: 16341056.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    108. Avidity-mediated enhancement of in vivo tumor targeting by single-chain Fv dimers. Clin Cancer Res. 2006 Mar 01; 12(5):1599-605. Adams GP, Tai MS, McCartney JE, Marks JD, Stafford WF, Houston LL, Huston JS, Weiner LM. PMID: 16533787.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    109. Isolation of scFvs to in vitro produced extracellular domains of EGFR family members. Cancer Biother Radiopharm. 2005 Dec; 20(6):603-13. Horak E, Heitner T, Robinson MK, Simmons HH, Garrison J, Russeva M, Furmanova P, Lou J, Zhou Y, Yuan QA, Weiner LM, Adams GP, Marks JD. PMID: 16398612.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    110. Sequence variation within botulinum neurotoxin serotypes impacts antibody binding and neutralization. Infect Immun. 2005 Sep; 73(9):5450-7. Smith TJ, Lou J, Geren IN, Forsyth CM, Tsai R, Laporte SL, Tepp WH, Bradshaw M, Johnson EA, Smith LA, Marks JD. PMID: 16113261; PMCID: PMC1231122.
      View in: PubMed   Mentions: 130     Fields:    Translation:AnimalsCells
    111. Molecular evolution of antibody affinity for sensitive detection of botulinum neurotoxin type A. J Mol Biol. 2005 Aug 05; 351(1):158-69. Razai A, Garcia-Rodriguez C, Lou J, Geren IN, Forsyth CM, Robles Y, Tsai R, Smith TJ, Smith LA, Siegel RW, Feldhaus M, Marks JD. PMID: 16002090.
      View in: PubMed   Mentions: 60     Fields:    Translation:Cells
    112. Infectious Disease and Bioterrorism. Anesthesiol Clin North Am. 2004 Sep; 22(3):xiii-xv. Hughes SC, Marks JD. PMID: 32288197; PMCID: PMC7127411.
      View in: PubMed   Mentions:    Fields:    
    113. Quantitative immuno-positron emission tomography imaging of HER2-positive tumor xenografts with an iodine-124 labeled anti-HER2 diabody. Cancer Res. 2005 Feb 15; 65(4):1471-8. Robinson MK, Doss M, Shaller C, Narayanan D, Marks JD, Adler LP, González Trotter DE, Adams GP. PMID: 15735035.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimals
    114. Preclinical manufacture of anti-HER2 liposome-inserting, scFv-PEG-lipid conjugate. 2. Conjugate micelle identity, purity, stability, and potency analysis. Biotechnol Prog. 2005 Jan-Feb; 21(1):221-32. Nellis DF, Giardina SL, Janini GM, Shenoy SR, Marks JD, Tsai R, Drummond DC, Hong K, Park JW, Ouellette TF, Perkins SC, Kirpotin DB. PMID: 15903261.
      View in: PubMed   Mentions: 21     Fields:    
    115. Preclinical manufacture of an anti-HER2 scFv-PEG-DSPE, liposome-inserting conjugate. 1. Gram-scale production and purification. Biotechnol Prog. 2005 Jan-Feb; 21(1):205-20. Nellis DF, Ekstrom DL, Kirpotin DB, Zhu J, Andersson R, Broadt TL, Ouellette TF, Perkins SC, Roach JM, Drummond DC, Hong K, Marks JD, Park JW, Giardina SL. PMID: 15903260.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    116. Human single chain Fv antibodies and a complementarity determining region-derived peptide binding to amyloid-beta 1-42. Neurobiol Dis. 2004 Oct; 17(1):114-21. Manoutcharian K, Acero G, Munguia ME, Becerril B, Massieu L, Govezensky T, Ortiz E, Marks JD, Cao C, Ugen K, Gevorkian G. PMID: 15350972.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    117. A single treatment of yttrium-90-labeled CHX-A"-C6.5 diabody inhibits the growth of established human tumor xenografts in immunodeficient mice. Cancer Res. 2004 Sep 01; 64(17):6200-6. Adams GP, Shaller CC, Dadachova E, Simmons HH, Horak EM, Tesfaye A, Klein-Szanto AJ, Marks JD, Brechbiel MW, Weiner LM. PMID: 15342405.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    118. Medical aspects of biologic toxins. Anesthesiol Clin North Am. 2004 Sep; 22(3):509-32, vii. Marks JD. PMID: 15325716.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    119. Development of ligand-targeted liposomes for cancer therapy. Expert Opin Ther Targets. 2004 Aug; 8(4):335-53. Noble CO, Kirpotin DB, Hayes ME, Mamot C, Hong K, Park JW, Benz CC, Marks JD, Drummond DC. PMID: 15268628.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimals
    120. Antibodies from phage antibody libraries. J Immunol Methods. 2004 Jul; 290(1-2):29-49. Bradbury AR, Marks JD. PMID: 15261570.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    121. Novel application of an in vitro technique to the detection and quantification of botulinum neurotoxin antibodies. J Immunol Methods. 2004 May; 288(1-2):55-60. Hall YH, Chaddock JA, Moulsdale HJ, Kirby ER, Alexander FC, Marks JD, Foster KA. PMID: 15183085.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    122. Yeast mating for combinatorial Fab library generation and surface display. FEBS Lett. 2004 Apr 23; 564(1-2):24-34. Weaver-Feldhaus JM, Lou J, Coleman JR, Siegel RW, Marks JD, Feldhaus MJ. PMID: 15094038.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    123. Deciphering antibody properties that lead to potent botulinum neurotoxin neutralization. Mov Disord. 2004 Mar; 19 Suppl 8:S101-8. Marks JD. PMID: 15027061.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    124. Characterization of a single-chain intrabody directed against the human receptor tyrosine kinase Ron. J Immunol Methods. 2004 Feb 01; 285(1):99-109. Secco P, Ferretti M, Gioia D, Cesaro P, Bozzo C, Marks JD, Santoro C. PMID: 14871539.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    125. Mapping tumor epitope space by direct selection of single-chain Fv antibody libraries on prostate cancer cells. Cancer Res. 2004 Jan 15; 64(2):704-10. Liu B, Conrad F, Cooperberg MR, Kirpotin DB, Marks JD. PMID: 14744788.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    126. Selection of human antibodies from phage display libraries. Methods Mol Biol. 2004; 248:161-76. Marks JD, Bradbury A. PMID: 14970495.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    127. Selection of internalizing antibodies for drug delivery. Methods Mol Biol. 2004; 248:201-8. Marks JD. PMID: 14970498.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    128. PCR cloning of human immunoglobulin genes. Methods Mol Biol. 2004; 248:117-34. Marks JD, Bradbury A. PMID: 14970493.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    129. Antibody affinity maturation by chain shuffling. Methods Mol Biol. 2004; 248:327-43. Marks JD. PMID: 14970506.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    130. Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- and EGFRvIII-overexpressing tumor cells. Cancer Res. 2003 Jun 15; 63(12):3154-61. Mamot C, Drummond DC, Greiser U, Hong K, Kirpotin DB, Marks JD, Park JW. PMID: 12810643.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansCells
    131. Predicting antigenic peptides suitable for the selection of phage antibodies. Hum Antibodies. 2003; 12(4):99-112. Pavlik P, Siegel RW, Marzari R, Sblattero D, Verzillo V, Collins C, Marks JD, Bradbury A. PMID: 15156098.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    132. The cleavage site of C5 from man and animals as a common target for neutralizing human monoclonal antibodies: in vitro and in vivo studies. Eur J Immunol. 2002 Oct; 32(10):2773-82. Marzari R, Sblattero D, Macor P, Fischetti F, Gennaro R, Marks JD, Bradbury A, Tedesco F. PMID: 12355429.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    133. Therapeutic efficacy of anti-ErbB2 immunoliposomes targeted by a phage antibody selected for cellular endocytosis. Biochim Biophys Acta. 2002 Aug 19; 1591(1-3):109-118. Nielsen UB, Kirpotin DB, Pickering EM, Hong K, Park JW, Refaat Shalaby M, Shao Y, Benz CC, Marks JD. PMID: 12183061.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    134. Potent neutralization of botulinum neurotoxin by recombinant oligoclonal antibody. Proc Natl Acad Sci U S A. 2002 Aug 20; 99(17):11346-50. Nowakowski A, Wang C, Powers DB, Amersdorfer P, Smith TJ, Montgomery VA, Sheridan R, Blake R, Smith LA, Marks JD. PMID: 12177434; PMCID: PMC123259.
      View in: PubMed   Mentions: 156     Fields:    Translation:AnimalsCells
    135. Phage versus phagemid libraries for generation of human monoclonal antibodies. J Mol Biol. 2002 Aug 02; 321(1):49-56. O'Connell D, Becerril B, Roy-Burman A, Daws M, Marks JD. PMID: 12139932.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    136. Generation and characterization of a protective monoclonal antibody to Pseudomonas aeruginosa PcrV. J Infect Dis. 2002 Jul 01; 186(1):64-73. Frank DW, Vallis A, Wiener-Kronish JP, Roy-Burman A, Spack EG, Mullaney BP, Megdoud M, Marks JD, Fritz R, Sawa T. PMID: 12089663.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    137. Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery. Clin Cancer Res. 2002 Apr; 8(4):1172-81. Park JW, Hong K, Kirpotin DB, Colbern G, Shalaby R, Baselga J, Shao Y, Nielsen UB, Marks JD, Moore D, Papahadjopoulos D, Benz CC. PMID: 11948130.
      View in: PubMed   Mentions: 163     Fields:    Translation:HumansAnimalsCells
    138. The intracellular antibody capture technology (IACT): towards a consensus sequence for intracellular antibodies. J Mol Biol. 2002 Mar 15; 317(1):73-83. Visintin M, Settanni G, Maritan A, Graziosi S, Marks JD, Cattaneo A. PMID: 11916379.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    139. Genetic and immunological comparison of anti-botulinum type A antibodies from immune and non-immune human phage libraries. Vaccine. 2002 Feb 22; 20(11-12):1640-8. Amersdorfer P, Wong C, Smith T, Chen S, Deshpande S, Sheridan R, Marks JD. PMID: 11858873.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    140. Phage-display antibody detection of Chlamydia trachomatis-associated antigens. Microbiology (Reading). 2002 Feb; 148(Pt 2):443-451. Lindquist EA, Marks JD, Kleba BJ, Stephens RS. PMID: 11832508.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    141. Towards proteome-wide production of monoclonal antibody by phage display. J Mol Biol. 2002 Feb 01; 315(5):1063-73. Liu B, Huang L, Sihlbom C, Burlingame A, Marks JD. PMID: 11827476.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    142. Epitope mapping of neutralizing botulinum neurotoxin A antibodies by phage display. Infect Immun. 2001 Oct; 69(10):6511-4. Mullaney BP, Pallavicini MG, Marks JD. PMID: 11553596; PMCID: PMC98787.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    143. Single-chain antibody-mediated gene delivery into ErbB2-positive human breast cancer cells. Cancer Gene Ther. 2001 Aug; 8(8):555-65. Li X, Stuckert P, Bosch I, Marks JD, Marasco WA. PMID: 11571533.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    144. Tumor targeting using anti-her2 immunoliposomes. J Control Release. 2001 Jul 06; 74(1-3):95-113. Park JW, Kirpotin DB, Hong K, Shalaby R, Shao Y, Nielsen UB, Marks JD, Papahadjopoulos D, Benz CC. PMID: 11489487.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimals
    145. High affinity restricts the localization and tumor penetration of single-chain fv antibody molecules. Cancer Res. 2001 Jun 15; 61(12):4750-5. Adams GP, Schier R, McCall AM, Simmons HH, Horak EM, Alpaugh RK, Marks JD, Weiner LM. PMID: 11406547.
      View in: PubMed   Mentions: 212     Fields:    Translation:HumansAnimals
    146. Increasing the affinity for tumor antigen enhances bispecific antibody cytotoxicity. J Immunol. 2001 May 15; 166(10):6112-7. McCall AM, Shahied L, Amoroso AR, Horak EM, Simmons HH, Nielson U, Adams GP, Schier R, Marks JD, Weiner LM. PMID: 11342630.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    147. Expression of single-chain Fv-Fc fusions in Pichia pastoris. J Immunol Methods. 2001 May 01; 251(1-2):123-35. Powers DB, Amersdorfer P, Poul M, Nielsen UB, Shalaby MR, Adams GP, Weiner LM, Marks JD. PMID: 11292488.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    148. Anomalous enhancement of botulinum toxin type A neurotoxicity in the presence of antitoxin. Toxicon. 2001 May; 39(5):651-7. Sheridan RE, Deshpande SS, Amersdorfer P, Marks JD, Smith T. PMID: 11072043.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    149. Antibodies to human fetal erythroid cells from a nonimmune phage antibody library. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2682-7. Huie MA, Cheung MC, Muench MO, Becerril B, Kan YW, Marks JD. PMID: 11226299; PMCID: PMC30198.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    150. Selection of cell binding and internalizing epidermal growth factor receptor antibodies from a phage display library. J Immunol Methods. 2001 Feb 01; 248(1-2):17-30. Heitner T, Moor A, Garrison JL, Marks C, Hasan T, Marks JD. PMID: 11223066.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    151. Biological effects of anti-ErbB2 single chain antibodies selected for internalizing function. Biochem Biophys Res Commun. 2001 Jan 12; 280(1):274-9. Neve RM, Nielsen UB, Kirpotin DB, Poul MA, Marks JD, Benz CC. PMID: 11162510.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    152. Engineering and characterization of a novel fusion protein incorporating B7.2 and an anti-ErbB-2 single-chain antibody fragment for the activation of Jurkat T cells. J Immunother. 2001 Jan-Feb; 24(1):27-36. Marshall KW, Marks JD. PMID: 11211146.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    153. Lung collapse during low tidal volume ventilation in acute respiratory distress syndrome. Respir Care. 2001 Jan; 46(1):49-52. Kallet RH, Siobal MS, Alonso JA, Warnecke EL, Katz JA, Marks JD. PMID: 11175238.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    154. Targeting of bivalent anti-ErbB2 diabody antibody fragments to tumor cells is independent of the intrinsic antibody affinity. Cancer Res. 2000 Nov 15; 60(22):6434-40. Nielsen UB, Adams GP, Weiner LM, Marks JD. PMID: 11103810.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    155. Applying phage antibodies to proteomics: selecting single chain Fv antibodies to antigens blotted on nitrocellulose. Anal Biochem. 2000 Nov 01; 286(1):119-28. Liu B, Marks JD. PMID: 11038282.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    156. Mass spectral analysis of a protein complex using single-chain antibodies selected on a peptide target: applications to functional genomics. J Mol Biol. 2000 Sep 15; 302(2):285-93. Siegel RW, Allen B, Pavlik P, Marks JD, Bradbury A. PMID: 10970733.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    157. Selection of tumor-specific internalizing human antibodies from phage libraries. J Mol Biol. 2000 Sep 01; 301(5):1149-61. Poul MA, Becerril B, Nielsen UB, Morisson P, Marks JD. PMID: 10966812.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    158. Measuring intra-esophageal pressure to assess transmural pulmonary arterial occlusion pressure in patients with acute lung injury: a case series and review. Respir Care. 2000 Sep; 45(9):1072-84. Kallet RH, Katz JA, Pittet JF, Ghermey J, Siobal M, Alonso JA, Marks JD. PMID: 10980099.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    159. Delivery of the alpha-emitting radioisotope bismuth-213 to solid tumors via single-chain Fv and diabody molecules. Nucl Med Biol. 2000 May; 27(4):339-46. Adams GP, Shaller CC, Chappell LL, Wu C, Horak EM, Simmons HH, Litwin S, Marks JD, Weiner LM, Brechbiel MW. PMID: 10938467.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    160. The treatment of acidosis in acute lung injury with tris-hydroxymethyl aminomethane (THAM). Am J Respir Crit Care Med. 2000 Apr; 161(4 Pt 1):1149-53. Kallet RH, Jasmer RM, Luce JM, Lin LH, Marks JD. PMID: 10764304.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    161. Improved flow and pressure capabilities of the Datex-Ohmeda SmartVent anesthesia ventilator. J Clin Anesth. 2000 Feb; 12(1):40-7. Katz JA, Kallet RH, Alonso JA, Marks JD. PMID: 10773507.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    162. Phage libraries for generation of anti-botulinum scFv antibodies. Methods Mol Biol. 2000; 145:219-40. Amersdorfer P, Marks JD. PMID: 10820725.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    163. Initial severity of metabolic acidosis predicts the development of acute lung injury in severely traumatized patients. Crit Care Med. 2000 Jan; 28(1):125-31. Eberhard LW, Morabito DJ, Matthay MA, Mackersie RC, Campbell AR, Marks JD, Alonso JA, Pittet JF. PMID: 10667511.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    164. Synthesis of Rh Fv phage-antibodies using VH and VL germline genes. Br J Haematol. 1999 Jun; 105(3):811-6. Hughes-Jones NC, Bye JM, Gorick BD, Marks JD, Ouwehand WH. PMID: 10354152.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    165. Disruption of anthrax toxin binding with the use of human antibodies and competitive inhibitors. Infect Immun. 1999 Jun; 67(6):2957-63. Cirino NM, Sblattero D, Allen D, Peterson SR, Marks JD, Jackson PJ, Bradbury A, Lehnert BE. PMID: 10338505; PMCID: PMC96606.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    166. Isolation and characterization of an anti-CD16 single-chain Fv fragment and construction of an anti-HER2/neu/anti-CD16 bispecific scFv that triggers CD16-dependent tumor cytolysis. Mol Immunol. 1999 May; 36(7):433-45. McCall AM, Adams GP, Amoroso AR, Nielsen UB, Zhang L, Horak E, Simmons H, Schier R, Marks JD, Weiner LM. PMID: 10449096.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    167. Targeted gene delivery to mammalian cells by filamentous bacteriophage. J Mol Biol. 1999 Apr 30; 288(2):203-11. Poul MA, Marks JD. PMID: 10329137.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    168. Toward selection of internalizing antibodies from phage libraries. Biochem Biophys Res Commun. 1999 Feb 16; 255(2):386-93. Becerril B, Poul MA, Marks JD. PMID: 10049718.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    169. Characterization of anti-mouse Fc gamma RII single-chain Fv fragments derived from human phage display libraries. Immunotechnology. 1998 Jun; 4(1):71-87. McCall AM, Amoroso AR, Sautès C, Marks JD, Weiner LM. PMID: 9661816.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    170. Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigens. Proc Natl Acad Sci U S A. 1998 May 26; 95(11):6157-62. Sheets MD, Amersdorfer P, Finnern R, Sargent P, Lindquist E, Schier R, Hemingsen G, Wong C, Gerhart JC, Marks JD, Lindqvist E. PMID: 9600934; PMCID: PMC27609.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansAnimalsCells
    171. Prolonged in vivo tumour retention of a human diabody targeting the extracellular domain of human HER2/neu. Br J Cancer. 1998 May; 77(9):1405-12. Adams GP, Schier R, McCall AM, Crawford RS, Wolf EJ, Weiner LM, Marks JD. PMID: 9652755; PMCID: PMC2150193.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    172. Acute withdrawal syndrome related to the administration of analgesic and sedative medications in adult intensive care unit patients. Crit Care Med. 1998 Apr; 26(4):676-84. Cammarano WB, Pittet JF, Weitz S, Schlobohm RM, Marks JD. PMID: 9559604.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    173. Increased affinity leads to improved selective tumor delivery of single-chain Fv antibodies. Cancer Res. 1998 Feb 01; 58(3):485-90. Adams GP, Schier R, Marshall K, Wolf EJ, McCall AM, Marks JD, Weiner LM. PMID: 9458094.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    174. Molecular characterization of murine humoral immune response to botulinum neurotoxin type A binding domain as assessed by using phage antibody libraries. Infect Immun. 1997 Sep; 65(9):3743-52. Amersdorfer P, Wong C, Chen S, Smith T, Deshpande S, Sheridan R, Finnern R, Marks JD. PMID: 9284147; PMCID: PMC175534.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    175. Antibody mapping to domains of botulinum neurotoxin serotype A in the complexed and uncomplexed forms. Infect Immun. 1997 May; 65(5):1626-30. Chen F, Kuziemko GM, Amersdorfer P, Wong C, Marks JD, Stevens RC. PMID: 9125539; PMCID: PMC175186.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    176. Human autoimmune anti-proteinase 3 scFv from a phage display library. Clin Exp Immunol. 1997 Feb; 107(2):269-81. Finnern R, Pedrollo E, Fisch I, Wieslander J, Marks JD, Lockwood CM, Ouwehand WH. PMID: 9030863; PMCID: PMC1904567.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    177. Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site. J Mol Biol. 1996 Nov 08; 263(4):551-67. Schier R, McCall A, Adams GP, Marshall KW, Merritt H, Yim M, Crawford RS, Weiner LM, Marks C, Marks JD. PMID: 8918938.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansCells
    178. Phage libraries--a new route to clinically useful antibodies. N Engl J Med. 1996 Sep 05; 335(10):730-3. Marks C, Marks JD. PMID: 8703174.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    179. Identification of functional and structural amino-acid residues by parsimonious mutagenesis. Gene. 1996 Mar 09; 169(2):147-55. Schier R, Balint RF, McCall A, Apell G, Larrick JW, Marks JD. PMID: 8647439.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    180. Isolation of high-affinity monomeric human anti-c-erbB-2 single chain Fv using affinity-driven selection. J Mol Biol. 1996 Jan 12; 255(1):28-43. Schier R, Bye J, Apell G, McCall A, Adams GP, Malmqvist M, Weiner LM, Marks JD. PMID: 8568873.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    181. Efficient in vitro affinity maturation of phage antibodies using BIAcore guided selections. Hum Antibodies Hybridomas. 1996; 7(3):97-105. Schier R, Marks JD. PMID: 9057057.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    182. Molecular characteristics of anti-self antibody fragments against neutrophil cytoplasmic antigens from human V gene phage display libraries. Clin Exp Immunol. 1995 Dec; 102(3):566-74. Finnern R, Bye JM, Dolman KM, Zhao MH, Short A, Marks JD, Lockwood MC, Ouwehand WH. PMID: 8536374; PMCID: PMC1553387.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    183. In vitro and in vivo characterization of a human anti-c-erbB-2 single-chain Fv isolated from a filamentous phage antibody library. Immunotechnology. 1995 May; 1(1):73-81. Schier R, Marks JD, Wolf EJ, Apell G, Wong C, McCartney JE, Bookman MA, Huston JS, Houston LL, Weiner LM, et al. PMID: 9373335.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    184. Characterization of human blood group scFv antibodies derived from a V gene phage-display library. Br J Haematol. 1994 Sep; 88(1):180-6. Hughes-Jones NC, Gorick BD, Bye JM, Finnern R, Scott ML, Voak D, Marks JD, Ouwehand WH. PMID: 7803241.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    185. In vitro assembly of repertoires of antibody chains on the surface of phage by renaturation. J Mol Biol. 1994 May 27; 239(1):68-78. Figini M, Marks JD, Winter G, Griffiths AD. PMID: 8196048.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    186. Fiberoptic-aided endobronchial intubation. Int Anesthesiol Clin. 1994; 32(4):75-84. Marks JD. PMID: 7875910.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    187. Performing fiberoptic endotracheal intubation: clinical aspects. Int Anesthesiol Clin. 1994; 32(4):57-73. Stackhouse RA, Marks JD, Bainton CR. PMID: 7875909.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    188. Practical aspects of fiberoptic laryngobronchoscopy. Int Anesthesiol Clin. 1994; 32(4):31-46. Marks JD, Bainton CR. PMID: 7875907.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    189. The humoral immune response against blood group antigens at the molecular level. Vox Sang. 1994; 67 Suppl 3:7-12. Ouwehand WH, Bye JM, Gorick BD, Marks JD, Timmers E, Griffin HM, Finnern R, Hughes-Jones N. PMID: 7975514.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    190. Human antibody fragments specific for human blood group antigens from a phage display library. Biotechnology (N Y). 1993 Oct; 11(10):1145-9. Marks JD, Ouwehand WH, Bye JM, Finnern R, Gorick BD, Voak D, Thorpe SJ, Hughes-Jones NC, Winter G. PMID: 7764095.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    191. Human anti-self antibodies with high specificity from phage display libraries. EMBO J. 1993 Feb; 12(2):725-34. Griffiths AD, Malmqvist M, Marks JD, Bye JM, Embleton MJ, McCafferty J, Baier M, Holliger KP, Gorick BD, Hughes-Jones NC, et al. PMID: 7679990; PMCID: PMC413258.
      View in: PubMed   Mentions: 78     Fields:    Translation:Cells
    192. Building antibodies from their genes. Immunol Rev. 1992 Dec; 130:41-68. Hoogenboom HR, Marks JD, Griffiths AD, Winter G. PMID: 1286871.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    193. Germline variable region gene segment derivation of human monoclonal anti-Rh(D) antibodies. Evidence for affinity maturation by somatic hypermutation and repertoire shift. J Clin Invest. 1992 Dec; 90(6):2481-90. Bye JM, Carter C, Cui Y, Gorick BD, Songsivilai S, Winter G, Hughes-Jones NC, Marks JD. PMID: 1469099; PMCID: PMC443405.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    194. The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops. J Mol Biol. 1992 Oct 05; 227(3):776-98. Tomlinson IM, Walter G, Marks JD, Llewelyn MB, Winter G. PMID: 1404388.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansCells
    195. Structural repertoire of the human VH segments. J Mol Biol. 1992 Oct 05; 227(3):799-817. Chothia C, Lesk AM, Gherardi E, Tomlinson IM, Walter G, Marks JD, Llewelyn MB, Winter G. PMID: 1404389.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    196. Molecular evolution of proteins on filamentous phage. Mimicking the strategy of the immune system. J Biol Chem. 1992 Aug 15; 267(23):16007-10. Marks JD, Hoogenboom HR, Griffiths AD, Winter G. PMID: 1644788.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    197. By-passing immunization: building high affinity human antibodies by chain shuffling. Biotechnology (N Y). 1992 Jul; 10(7):779-83. Marks JD, Griffiths AD, Malmqvist M, Clackson TP, Bye JM, Winter G. PMID: 1368267.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCellsPHPublic Health
    198. An artificial immune system for making antibodies. Behring Inst Mitt. 1992 Apr; (91):6-12. Marks JD, Winter G. PMID: 1524572.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    199. By-passing immunization. Human antibodies from V-gene libraries displayed on phage. J Mol Biol. 1991 Dec 05; 222(3):581-97. Marks JD, Hoogenboom HR, Bonnert TP, McCafferty J, Griffiths AD, Winter G. PMID: 1748994.
      View in: PubMed   Mentions: 362     Fields:    Translation:HumansCells
    200. Airway management for trauma patients with potential cervical spine injuries. Anesth Analg. 1991 Oct; 73(4):471-82. Hastings RH, Marks JD. PMID: 1897772.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    201. Oligonucleotide primers for polymerase chain reaction amplification of human immunoglobulin variable genes and design of family-specific oligonucleotide probes. Eur J Immunol. 1991 Apr; 21(4):985-91. Marks JD, Tristem M, Karpas A, Winter G. PMID: 2019291.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    202. Factors affecting perioperative pulmonary function in acute respiratory failure. Chest. 1990 Dec; 98(6):1455-62. Biery DR, Marks JD, Schapera A, Autry M, Schlobohm RM, Katz JA. PMID: 2123151.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    203. Cloning and sequencing of human lambda immunoglobulin genes by the polymerase chain reaction. Eur J Immunol. 1990 Dec; 20(12):2661-6. Songsivilai S, Bye JM, Marks JD, Hughes-Jones NC. PMID: 2125272.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    204. Elevated von Willebrand factor antigen is an early plasma predictor of acute lung injury in nonpulmonary sepsis syndrome. J Clin Invest. 1990 Aug; 86(2):474-80. Rubin DB, Wiener-Kronish JP, Murray JF, Green DR, Turner J, Luce JM, Montgomery AB, Marks JD, Matthay MA. PMID: 2384595; PMCID: PMC296749.
      View in: PubMed   Mentions: 69     Fields:    Translation:Humans
    205. Plasma tumor necrosis factor in patients with septic shock. Mortality rate, incidence of adult respiratory distress syndrome, and effects of methylprednisolone administration. Am Rev Respir Dis. 1990 Jan; 141(1):94-7. Marks JD, Marks CB, Luce JM, Montgomery AB, Turner J, Metz CA, Murray JF. PMID: 2297191.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCTClinical Trials
    206. Perioperative pulmonary function in acute respiratory failure: effect of ventilator type and gas mixture. Anesthesiology. 1989 Sep; 71(3):396-402. Schapera A, Marks JD, Minagi H, Goodman P, Katz JA. PMID: 2774267.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    207. Pressure and flow limitations of anesthesia ventilators. Anesthesiology. 1989 Sep; 71(3):403-8. Marks JD, Schapera A, Kraemer RW, Katz JA. PMID: 2672901.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    208. Ineffectiveness of high-dose methylprednisolone in preventing parenchymal lung injury and improving mortality in patients with septic shock. Am Rev Respir Dis. 1988 Jul; 138(1):62-8. Luce JM, Montgomery AB, Marks JD, Turner J, Metz CA, Murray JF. PMID: 3202402.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansCTClinical Trials
    209. Poor correlation between pulmonary arterial wedge pressure and left ventricular end-diastolic volume after coronary artery bypass graft surgery. Anesthesiology. 1986 Jun; 64(6):764-70. Hansen RM, Viquerat CE, Matthay MA, Wiener-Kronish JP, DeMarco T, Bahtia S, Marks JD, Botvinick EH, Chatterjee K. PMID: 3487261.
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    210. Inspiratory work with and without continuous positive airway pressure in patients with acute respiratory failure. Anesthesiology. 1985 Dec; 63(6):598-607. Katz JA, Marks JD. PMID: 3904528.
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