Bridget Ostrem, MD, PhD

Title(s)Assistant Professor, Neurology
SchoolSchool of Medicine
Address675 Nelson Rising Lane, #411
San Francisco CA 94158
ORCID ORCID Icon0000-0003-2107-3930 Additional info
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    Collapse Biography 
    Collapse Education and Training
    UCSF, San Francisco, CA, USAMD06/2016Medicine
    UCSF, San Francisco, CA, USAPhD03/2014Neuroscience
    Partners Neurology Residency, Boston, MA, USA06/2020Neurology with Special Qualification in Child Neurology
    Brigham and Women's Hospital, Boston, MA, USA06/2021Women's Neurology Fellowship
    Collapse Awards and Honors
    MGH2020  - 2022NIH-NINDS R25 Award
    UCSF2012  - 2014California Institute of Regenerative Medicine Predoctoral Grant
    UCSF2016  - 2016Alpha Omega Alpha Honor Medical Society Awardee

    Collapse Overview 
    Collapse Overview
    Dr. Ostrem has expertise in Maternal-Fetal and Neonatal Neurology and treats babies, children, young adults, and pregnant patients with neurological symptoms and disorders. She completed her M.D. and Ph.D. at UCSF followed by residency in Pediatric Neurology in the Mass General Brigham (Partners Neurology) Program in Boston, Massachusetts, and clinical fellowship in Women's Neurology at Brigham and Women's Hospital. She also completed a postdoctoral fellowship in the laboratory of Dr. Paola Arlotta at Harvard. Dr. Ostrem's research focuses on developing novel strategies for neuroprotection and repair in the fetal and neonatal brain, and understanding how maternal factors impact brain development.

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Minimum effective dose of clemastine in a mouse model of preterm white matter injury. Pediatr Res. 2024 Jun 28. Odell EP, Jabassini N, Schniedewind B, Pease-Raissi SE, Frymoyer A, Christians U, Green AJ, Chan JR, Ostrem BEL. PMID: 38942888.
      View in: PubMed   Mentions:    Fields:    
    2. Fetal brain response to maternal inflammation requires microglia. Development. 2024 05 15; 151(10). Ostrem BEL, Domínguez-Iturza N, Stogsdill JA, Faits T, Kim K, Levin JZ, Arlotta P. PMID: 38775708; PMCID: PMC11190434.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. Minimum Effective Dose of Clemastine in a Mouse Model of Preterm White Matter Injury. bioRxiv. 2024 Mar 01. Odell E, Jabassini N, Schniedewind B, Pease-Raissi SE, Frymoyer A, Christians U, Green AJ, Chan JR, Ostrem BEL. PMID: 38464078; PMCID: PMC10925142.
      View in: PubMed   Mentions:
    4. Monogenic Causes of Cerebrovascular Disease in Childhood: A Case Series. Pediatr Neurol. 2023 Dec; 149:39-43. Ostrem BEL, Godfrey D, Caruso PA, Musolino PL. PMID: 37776659.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Acquired Brain Injuries Across the Perinatal Spectrum: Pathophysiology and Emerging Therapies. Pediatr Neurol. 2023 Nov; 148:206-214. Russ JB, Ostrem BEL. PMID: 37625929.
      View in: PubMed   Mentions:    Fields:    
    6. Inflammatory Activity After Diverse Fertility Treatments: A Multicenter Analysis in the Modern Multiple Sclerosis Treatment Era. Neurol Neuroimmunol Neuroinflamm. 2023 05; 10(3). Graham EL, Bakkensen JB, Anderson A, Lancki N, Davidson A, Perez Giraldo G, Jungheim ES, Vanderhoff AC, Ostrem B, Mok-Lin E, Huang D, Bevan CJ, Jacobs D, Kaplan TB, Houtchens MK, Bove R. PMID: 36922025; PMCID: PMC10018493.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    7. Peripartum disease activity in moderately and severely disabled women with multiple sclerosis. Mult Scler J Exp Transl Clin. 2022 Apr-Jun; 8(2):20552173221104918. Ostrem BL, Anderson A, Conway S, Healy BC, Oh J, Jacobs D, Dobson R, Graham EL, Sadovnick AD, Zimmerman V, Liu Y, Bove R, Houtchens M. PMID: 35734229; PMCID: PMC9208060.
      View in: PubMed   Mentions: 1  
    8. Enhanced Virus Detection and Metagenomic Sequencing in Patients with Meningitis and Encephalitis. mBio. 2021 08 31; 12(4):e0114321. Piantadosi A, Mukerji SS, Ye S, Leone MJ, Freimark LM, Park D, Adams G, Lemieux J, Kanjilal S, Solomon IH, Ahmed AA, Goldstein R, Ganesh V, Ostrem B, Cummins KC, Thon JM, Kinsella CM, Rosenberg E, Frosch MP, Goldberg MB, Cho TA, Sabeti P. PMID: 34465023; PMCID: PMC8406231.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    9. De Novo Variants in the ATPase Module of MORC2 Cause a Neurodevelopmental Disorder with Growth Retardation and Variable Craniofacial Dysmorphism. Am J Hum Genet. 2020 08 06; 107(2):352-363. Guillen Sacoto MJ, Tchasovnikarova IA, Torti E, Forster C, Andrew EH, Anselm I, Baranano KW, Briere LC, Cohen JS, Craigen WJ, Cytrynbaum C, Ekhilevitch N, Elrick MJ, Fatemi A, Fraser JL, Gallagher RC, Guerin A, Haynes D, High FA, Inglese CN, Kiss C, Koenig MK, Krier J, Lindstrom K, Marble M, Meddaugh H, Moran ES, Morel CF, Mu W, Muller EA, Nance J, Natowicz MR, Numis AL, Ostrem B, Pappas J, Stafstrom CE, Streff H, Sweetser DA, Szybowska M, Undiagnosed Diseases Network, Walker MA, Wang W, Weiss K, Weksberg R, Wheeler PG, Yoon G, Kingston RE, Juusola J. PMID: 32693025; PMCID: PMC7413887.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    10. oRGs and mitotic somal translocation - a role in development and disease. Curr Opin Neurobiol. 2017 02; 42:61-67. Ostrem B, Di Lullo E, Kriegstein A. PMID: 27978479; PMCID: PMC5638645.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    11. Control of outer radial glial stem cell mitosis in the human brain. Cell Rep. 2014 Aug 07; 8(3):656-64. Ostrem BE, Lui JH, Gertz CC, Kriegstein AR. PMID: 25088420; PMCID: PMC4127493.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    12. Diverse behaviors of outer radial glia in developing ferret and human cortex. J Neurosci. 2014 Feb 12; 34(7):2559-70. Gertz CC, Lui JH, LaMonica BE, Wang X, Kriegstein AR. PMID: 24523546; PMCID: PMC3921426.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    13. Mitotic spindle orientation predicts outer radial glial cell generation in human neocortex. Nat Commun. 2013; 4:1665. LaMonica BE, Lui JH, Hansen DV, Kriegstein AR. PMID: 23575669; PMCID: PMC3625970.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansCells
    14. OSVZ progenitors in the human cortex: an updated perspective on neurodevelopmental disease. Curr Opin Neurobiol. 2012 Oct; 22(5):747-53. LaMonica BE, Lui JH, Wang X, Kriegstein AR. PMID: 22487088; PMCID: PMC3402619.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    15. A new subtype of progenitor cell in the mouse embryonic neocortex. Nat Neurosci. 2011 May; 14(5):555-61. Wang X, Tsai JW, LaMonica B, Kriegstein AR. PMID: 21478886; PMCID: PMC3083489.
      View in: PubMed   Mentions: 240     Fields:    Translation:AnimalsCells
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