Caitlin Roake, MD

Title(s)Resident Physician, Emergency Medicine - Fresno
SchoolSchool of Medicine
AddressLocation Required, #001
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    Stanford UniversityMD06/2020Medicine
    Stanford UniversityPhD06/2020Cancer Biology

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration. Nucleic Acids Res. 2022 Aug 10. Chen L, Roake CM, Maccallini P, Bavasso F, Dehghannasiri R, Santonicola P, Mendoza-Ferreira N, Scatolini L, Rizzuti L, Esposito A, Gallotta I, Francia S, Cacchione S, Galati A, Palumbo V, Kobin MA, Tartaglia GG, Colantoni A, Proietti G, Wu Y, Hammerschmidt M, De Pittà C, Sales G, Salzman J, Pellizzoni L, Wirth B, Schiavi ED, Gatti M, Artandi SE, Raffa GD. PMID: 35947650.
      View in: PubMed   Mentions: 2     Fields:    
    2. The S-adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening. FEBS Lett. 2022 01; 596(1):42-52. Galati A, Scatolini L, Micheli E, Bavasso F, Cicconi A, Maccallini P, Chen L, Roake CM, Schoeftner S, Artandi SE, Gatti M, Cacchione S, Raffa GD. PMID: 34817067.
      View in: PubMed   Mentions: 2     Fields:    
    3. Acinar cell clonal expansion in pancreas homeostasis and carcinogenesis. Nature. 2021 09; 597(7878):715-719. Neuhöfer P, Roake CM, Kim SJ, Lu RJ, West RB, Charville GW, Artandi SE. PMID: 34526722; PMCID: PMC9347609.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    4. Tissue-specific telomere shortening and degenerative changes in a patient with TINF2 mutation and dyskeratosis congenita. Hum Pathol (N Y). 2021 Sep; 25. Roake CM, Juntilla M, Agarwal-Hashmi R, Artandi S, Kuo CS. PMID: 34522616; PMCID: PMC8437149.
      View in: PubMed   Mentions:
    5. Regulation of human telomerase in homeostasis and disease. Nat Rev Mol Cell Biol. 2020 07; 21(7):384-397. Roake CM, Artandi SE. PMID: 32242127; PMCID: PMC7377944.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansCells
    6. Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation. Cell Rep. 2020 02 04; 30(5):1358-1372.e5. Chen L, Roake CM, Galati A, Bavasso F, Micheli E, Saggio I, Schoeftner S, Cacchione S, Gatti M, Artandi SE, Raffa GD. PMID: 32023455; PMCID: PMC7156301.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    7. HiChIRP reveals RNA-associated chromosome conformation. Nat Methods. 2019 06; 16(6):489-492. Mumbach MR, Granja JM, Flynn RA, Roake CM, Satpathy AT, Rubin AJ, Qi Y, Jiang Z, Shams S, Louie BH, Guo JK, Gennert DG, Corces MR, Khavari PA, Atianand MK, Artandi SE, Fitzgerald KA, Greenleaf WJ, Chang HY. PMID: 31133759; PMCID: PMC6638558.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    8. Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease. Mol Cell. 2019 05 16; 74(4):688-700.e3. Roake CM, Chen L, Chakravarthy AL, Ferrell JE, Raffa GD, Artandi SE. PMID: 30930056; PMCID: PMC6525023.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    9. An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1. Cell. 2018 06 28; 174(1):218-230.e13. Chen L, Roake CM, Freund A, Batista PJ, Tian S, Yin YA, Gajera CR, Lin S, Lee B, Pech MF, Venteicher AS, Das R, Chang HY, Artandi SE. PMID: 29804836; PMCID: PMC6063371.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    10. Approaching TERRA Firma: Genomic Functions of Telomeric Noncoding RNA. Cell. 2017 06 29; 170(1):8-9. Roake CM, Artandi SE. PMID: 28666127.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    11. Control of Cellular Aging, Tissue Function, and Cancer by p53 Downstream of Telomeres. Cold Spring Harb Perspect Med. 2017 May 01; 7(5). Roake CM, Artandi SE. PMID: 28289249; PMCID: PMC5411683.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    12. DNA repair: Telomere-lengthening mechanism revealed. Nature. 2016 11 03; 539(7627):35-36. Roake CM, Artandi SE. PMID: 27760112.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    13. Keeping It in the Family: ATRX Loss Promotes Persistent Sister Telomere Cohesion in ALT Cancer Cells. Cancer Cell. 2015 Sep 14; 28(3):277-9. Roake CM, Artandi SE. PMID: 26373274.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    14. Characterization of the cell of origin for small cell lung cancer. Cell Cycle. 2011 Aug 15; 10(16):2806-15. Park KS, Liang MC, Raiser DM, Zamponi R, Roach RR, Curtis SJ, Walton Z, Schaffer BE, Roake CM, Zmoos AF, Kriegel C, Wong KK, Sage J, Kim CF. PMID: 21822053; PMCID: PMC3219544.
      View in: PubMed   Mentions: 106     Fields:    Translation:AnimalsCells
    15. Regulation of RB transcription in vivo by RB family members. Mol Cell Biol. 2010 Apr; 30(7):1729-45. Burkhart DL, Ngai LK, Roake CM, Viatour P, Thangavel C, Ho VM, Knudsen ES, Sage J. PMID: 20100864; PMCID: PMC2838078.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
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