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Contribution of G-Protein α-Subunits to Analgesia, Hyperalgesia, and Hyperalgesic Priming Induced by Subanalgesic and Analgesic Doses of Fentanyl and Morphine. J Neurosci. 2022 02 16; 42(7):1196-1210.
Araldi D, Bonet IJM, Green PG, Levine JD. PMID: 34965973; PMCID: PMC8883871.
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Animals
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Neuroendocrine Stress Axis-Dependence of Duloxetine Analgesia (Anti-Hyperalgesia) in Chemotherapy-Induced Peripheral Neuropathy. J Neurosci. 2022 01 19; 42(3):405-415.
Staurengo-Ferrari L, Bonet IJM, Araldi D, Green PG, Levine JD. PMID: 34880120; PMCID: PMC8802923.
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Animals
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Second messengers mediating high-molecular-weight hyaluronan-induced antihyperalgesia in rats with chemotherapy-induced peripheral neuropathy. Pain. 2022 09 01; 163(9):1728-1739.
Bonet IJM, Staurengo-Ferrari L, Araldi D, Green PG, Levine JD. PMID: 34913881; PMCID: PMC9167889.
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1 Fields:
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AnimalsCells
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Depolarization induces nociceptor sensitization by CaV1.2-mediated PKA-II activation. J Cell Biol. 2021 10 04; 220(10).
Isensee J, van Cann M, Despang P, Araldi D, Moeller K, Petersen J, Schmidtko A, Matthes J, Levine JD, Hucho T. PMID: 34431981; PMCID: PMC8404467.
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1 Fields:
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AnimalsCells
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PI3K?/AKT Signaling in High Molecular Weight Hyaluronan (HMWH)-Induced Anti-Hyperalgesia and Reversal of Nociceptor Sensitization. J Neurosci. 2021 10 06; 41(40):8414-8426.
Bonet IJM, Khomula EV, Araldi D, Green PG, Levine JD. PMID: 34417329; PMCID: PMC8496198.
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2 Fields:
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AnimalsCells
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Sexually Dimorphic Role of Toll-like Receptor 4 (TLR4) in High Molecular Weight Hyaluronan (HMWH)-induced Anti-hyperalgesia. J Pain. 2021 10; 22(10):1273-1282.
Bonet IJM, Araldi D, Green PG, Levine JD. PMID: 33892155; PMCID: PMC8500912.
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4 Fields:
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AnimalsCells
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Sexual dimorphism in the contribution of neuroendocrine stress axes to oxaliplatin-induced painful peripheral neuropathy. Pain. 2021 03 01; 162(3):907-918.
Staurengo-Ferrari L, Green PG, Araldi D, Ferrari LF, Miaskowski C, Levine JD. PMID: 32947545; PMCID: PMC7886966.
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4 Fields:
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Animals
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Involvement of TACAN, a Mechanotransducing Ion Channel, in Inflammatory But Not Neuropathic Hyperalgesia in the Rat. J Pain. 2021 05; 22(5):498-508.
Bonet IJM, Araldi D, Bogen O, Levine JD. PMID: 33232830; PMCID: PMC8122021.
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8 Fields:
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AnimalsCells
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Opioid-Induced Hyperalgesic Priming in Single Nociceptors. J Neurosci. 2021 01 06; 41(1):31-46.
Khomula EV, Araldi D, Bonet IJM, Levine JD. PMID: 33203743; PMCID: PMC7786210.
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6 Fields:
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AnimalsCells
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7 Fields:
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AnimalsCells
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Peripheral Inflammatory Hyperalgesia Depends on P2X7 Receptors in Satellite Glial Cells. Front Physiol. 2020; 11:473.
Neves AF, Farias FH, de Magalh?es SF, Araldi D, Pagliusi M, Tambeli CH, Sartori CR, Lotufo CMDC, Parada CA. PMID: 32523543; PMCID: PMC7261868.
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8
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Marked sexual dimorphism in neuroendocrine mechanisms for the exacerbation of paclitaxel-induced painful peripheral neuropathy by stress. Pain. 2020 04; 161(4):865-874.
Ferrari LF, Araldi D, Green PG, Levine JD. PMID: 31917777; PMCID: PMC7085433.
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13 Fields:
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Animals
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In Vitro Nociceptor Neuroplasticity Associated with In Vivo Opioid-Induced Hyperalgesia. J Neurosci. 2019 09 04; 39(36):7061-7073.
Khomula EV, Araldi D, Levine JD. PMID: 31300521; PMCID: PMC6733538.
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9 Fields:
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AnimalsCells
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Role of Nociceptor Toll-like Receptor 4 (TLR4) in Opioid-Induced Hyperalgesia and Hyperalgesic Priming. J Neurosci. 2019 08 14; 39(33):6414-6424.
Araldi D, Bogen O, Green PG, Levine JD. PMID: 31209174; PMCID: PMC6697398.
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20 Fields:
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AnimalsCells
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Systemic Morphine Produces Dose-dependent Nociceptor-mediated Biphasic Changes in Nociceptive Threshold and Neuroplasticity. Neuroscience. 2019 02 01; 398:64-75.
Ferrari LF, Araldi D, Bogen O, Green PG, Levine JD. PMID: 30529265.
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9 Fields:
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AnimalsCells
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Mu-opioid Receptor (MOR) Biased Agonists Induce Biphasic Dose-dependent Hyperalgesia and Analgesia, and Hyperalgesic Priming in the Rat. Neuroscience. 2018 12 01; 394:60-71.
Araldi D, Ferrari LF, Levine JD. PMID: 30342200; PMCID: PMC6261666.
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13 Fields:
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Animals
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Role of GPCR (mu-opioid)-receptor tyrosine kinase (epidermal growth factor) crosstalk in opioid-induced hyperalgesic priming (type II). Pain. 2018 May; 159(5):864-875.
Araldi D, Ferrari LF, Levine JD. PMID: 29447132; PMCID: PMC5908744.
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12 Fields:
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AnimalsCells
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Fentanyl Induces Rapid Onset Hyperalgesic Priming: Type I at Peripheral and Type II at Central Nociceptor Terminals. J Neurosci. 2018 02 28; 38(9):2226-2245.
Araldi D, Khomula EV, Ferrari LF, Levine JD. PMID: 29431655; PMCID: PMC5830512.
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16 Fields:
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AnimalsCells
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CD44 Signaling Mediates High Molecular Weight Hyaluronan-Induced Antihyperalgesia. J Neurosci. 2018 01 10; 38(2):308-321.
Ferrari LF, Khomula EV, Araldi D, Levine JD. PMID: 29175954; PMCID: PMC5761612.
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23 Fields:
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AnimalsCells
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Hyperalgesic priming (type II) induced by repeated opioid exposure: maintenance mechanisms. Pain. 2017 07; 158(7):1204-1216.
Araldi D, Ferrari LF, Levine JD. PMID: 28306605; PMCID: PMC5474187.
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PubMed Mentions:
25 Fields:
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AnimalsCells
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Age-Dependent Sexual Dimorphism in Susceptibility to Develop Chronic Pain in the Rat. Neuroscience. 2018 09 01; 387:170-177.
Ferrari LF, Araldi D, Green P, Levine JD. PMID: 28676241; PMCID: PMC5748377.
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3 Fields:
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Animals
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Antihyperalgesic effect of CB1 receptor activation involves the modulation of P2X3 receptor in the primary afferent neuron. Eur J Pharmacol. 2017 Mar 05; 798:113-121.
Oliveira-Fusaro MCG, Zanoni CIS, Dos Santos GG, Manzo LP, Araldi D, Bonet IJM, Tambeli CH, Dias EV, Parada CA. PMID: 28131783.
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18 Fields:
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AnimalsCells
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Sexual Dimorphism in a Reciprocal Interaction of Ryanodine and IP3 Receptors in the Induction of Hyperalgesic Priming. J Neurosci. 2017 02 22; 37(8):2032-2044.
Khomula EV, Ferrari LF, Araldi D, Levine JD. PMID: 28115480; PMCID: PMC5338754.
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27 Fields:
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AnimalsCells
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Regulation of Expression of Hyperalgesic Priming by Estrogen Receptor a in the Rat. J Pain. 2017 05; 18(5):574-582.
Ferrari LF, Araldi D, Levine JD. PMID: 28089711; PMCID: PMC5429204.
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PubMed Mentions:
5 Fields:
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Animals
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Marked sexual dimorphism in 5-HT1 receptors mediating pronociceptive effects of sumatriptan. Neuroscience. 2017 03 06; 344:394-405.
Araldi D, Ferrari LF, Green P, Levine JD. PMID: 28040566; PMCID: PMC5321636.
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14 Fields:
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AnimalsCells
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Janus kinase 2 activation participates in prostaglandin E2-induced hyperalgesia. Life Sci. 2016 Dec 01; 166:8-12.
Vieira AS, Araldi D, Dias EV, do Prado FC, Tambeli CH, Parada CA. PMID: 27717845.
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2 Fields:
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AnimalsCells
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Marked Sexual Dimorphism in the Role of the Ryanodine Receptor in a Model of Pain Chronification in the Rat. Sci Rep. 2016 08 08; 6:31221.
Ferrari LF, Khomula EV, Araldi D, Levine JD. PMID: 27499186; PMCID: PMC4976309.
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36 Fields:
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AnimalsCells
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Gi-protein-coupled 5-HT1B/D receptor agonist sumatriptan induces type I hyperalgesic priming. Pain. 2016 08; 157(8):1773-1782.
Araldi D, Ferrari LF, Levine JD. PMID: 27075428; PMCID: PMC5048915.
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PubMed Mentions:
21 Fields:
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AnimalsCells
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Extracellular matrix hyaluronan signals via its CD44 receptor in the increased responsiveness to mechanical stimulation. Neuroscience. 2016 Jun 02; 324:390-8.
Ferrari LF, Araldi D, Bogen O, Levine JD. PMID: 26996509; PMCID: PMC5365238.
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12 Fields:
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AnimalsCells
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Adenosine-A1 receptor agonist induced hyperalgesic priming type II. Pain. 2016 Mar; 157(3):698-709.
Araldi D, Ferrari LF, Levine JD. PMID: 26588695; PMCID: PMC5048916.
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PubMed Mentions:
20 Fields:
Translation:
Animals
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Repeated Mu-Opioid Exposure Induces a Novel Form of the Hyperalgesic Priming Model for Transition to Chronic Pain. J Neurosci. 2015 Sep 09; 35(36):12502-17.
Araldi D, Ferrari LF, Levine JD. PMID: 26354917; PMCID: PMC4563038.
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38 Fields:
Translation:
Animals
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Distinct terminal and cell body mechanisms in the nociceptor mediate hyperalgesic priming. J Neurosci. 2015 Apr 15; 35(15):6107-16.
Ferrari LF, Araldi D, Levine JD. PMID: 25878283; PMCID: PMC4397607.
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29 Fields:
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AnimalsCells
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Inflammatory sensitization of nociceptors depends on activation of NMDA receptors in DRG satellite cells. Proc Natl Acad Sci U S A. 2014 Dec 23; 111(51):18363-8.
Ferrari LF, Lotufo CM, Araldi D, Rodrigues MA, Macedo LP, Ferreira SH, Parada CA. PMID: 25489099; PMCID: PMC4280647.
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25 Fields:
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AnimalsCells
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P2X3 receptors induced inflammatory nociception modulated by TRPA1, 5-HT3 and 5-HT1A receptors. Pharmacol Biochem Behav. 2013 Nov; 112:49-55.
Krimon S, Araldi D, do Prado FC, Tambeli CH, Oliveira-Fusaro MC, Parada CA. PMID: 24120766.
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2 Fields:
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Animals
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Peripheral inflammatory hyperalgesia depends on the COX increase in the dorsal root ganglion. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3603-8.
Araldi D, Ferrari LF, Lotufo CM, Vieira AS, Athi? MC, Figueiredo JG, Duarte DB, Tambeli CH, Ferreira SH, Parada CA. PMID: 23401543; PMCID: PMC3587281.
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21 Fields:
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AnimalsCells
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Neuronal P2X3 receptor activation is essential to the hyperalgesia induced by prostaglandins and sympathomimetic amines released during inflammation. Neuropharmacology. 2013 Apr; 67:252-8.
Prado FC, Araldi D, Vieira AS, Oliveira-Fusaro MC, Tambeli CH, Parada CA. PMID: 23186588.
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PubMed Mentions:
21 Fields:
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AnimalsCells
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Nanoassisted laser desorption-ionization-MS imaging of tumors. Anal Chem. 2012 Aug 07; 84(15):6341-5.
Tata A, Fernandes AM, Santos VG, Alberici RM, Araldi D, Parada CA, Braguini W, Veronez L, Silva Bisson G, Reis FH, Alberici LC, Eberlin MN. PMID: 22741519.
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PubMed Mentions:
7 Fields:
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HumansAnimalsCells
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Inflammation-induced decrease in voluntary wheel running in mice: a nonreflexive test for evaluating inflammatory pain and analgesia. Pain. 2012 Apr; 153(4):876-884.
Cobos EJ, Ghasemlou N, Araldi D, Segal D, Duong K, Woolf CJ. PMID: 22341563; PMCID: PMC3319437.
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110 Fields:
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Animals
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P2X3 and P2X2/3 receptors mediate mechanical hyperalgesia induced by bradykinin, but not by pro-inflammatory cytokines, PGE2 or dopamine. Eur J Pharmacol. 2010 Dec 15; 649(1-3):177-82.
de Oliveira Fusaro MC, Pelegrini-da-Silva A, Araldi D, Parada CA, Tambeli CH. PMID: 20868656.
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11 Fields:
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AnimalsCells
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Acute diphenyl diselenide treatment reduces hyperglycemia but does not change delta-aminolevulinate dehydratase activity in alloxan-induced diabetes in rats. Biol Pharm Bull. 2008 Dec; 31(12):2200-4.
Barbosa NB, Oliveira C, Araldi D, Folmer V, Rocha JB, Nogueira CW. PMID: 19043199.
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7 Fields:
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Animals
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On the mechanisms involved in antinociception induced by diphenyl diselenide. Environ Toxicol Pharmacol. 2005 Feb; 19(2):283-9.
Zasso FB, Goncales CE, Jung EA, Araldi D, Zeni G, Rocha JB, Nogueira CW. PMID: 21783487.
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5 Fields:
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Antinociceptive properties of acetylenic thiophene and furan derivatives: evidence for the mechanism of action. Life Sci. 2005 Mar 25; 76(19):2221-34.
Goncales CE, Araldi D, Panatieri RB, Rocha JB, Zeni G, Nogueira CW. PMID: 15733937.
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PubMed Mentions:
5 Fields:
Translation:
Animals