Dioneia Araldi, PhD

Title(s)Associate Researcher, Oral & Maxillofacial Surgery
SchoolSchool of Dentistry
Address513 Parnassus Ave, MSB, #709
San Francisco CA 94117
ORCID ORCID Icon0000-0001-8379-2901 Additional info
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Contribution of G-Protein α-Subunits to Analgesia, Hyperalgesia, and Hyperalgesic Priming Induced by Subanalgesic and Analgesic Doses of Fentanyl and Morphine. J Neurosci. 2022 02 16; 42(7):1196-1210. Araldi D, Bonet IJM, Green PG, Levine JD. PMID: 34965973; PMCID: PMC8883871.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    2. Neuroendocrine Stress Axis-Dependence of Duloxetine Analgesia (Anti-Hyperalgesia) in Chemotherapy-Induced Peripheral Neuropathy. J Neurosci. 2022 01 19; 42(3):405-415. Staurengo-Ferrari L, Bonet IJM, Araldi D, Green PG, Levine JD. PMID: 34880120; PMCID: PMC8802923.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    3. Second messengers mediating high-molecular-weight hyaluronan-induced antihyperalgesia in rats with chemotherapy-induced peripheral neuropathy. Pain. 2022 09 01; 163(9):1728-1739. Bonet IJM, Staurengo-Ferrari L, Araldi D, Green PG, Levine JD. PMID: 34913881; PMCID: PMC9167889.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    4. Depolarization induces nociceptor sensitization by CaV1.2-mediated PKA-II activation. J Cell Biol. 2021 10 04; 220(10). Isensee J, van Cann M, Despang P, Araldi D, Moeller K, Petersen J, Schmidtko A, Matthes J, Levine JD, Hucho T. PMID: 34431981; PMCID: PMC8404467.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    5. PI3Kγ/AKT Signaling in High Molecular Weight Hyaluronan (HMWH)-Induced Anti-Hyperalgesia and Reversal of Nociceptor Sensitization. J Neurosci. 2021 10 06; 41(40):8414-8426. Bonet IJM, Khomula EV, Araldi D, Green PG, Levine JD. PMID: 34417329; PMCID: PMC8496198.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    6. Sexually Dimorphic Role of Toll-like Receptor 4 (TLR4) in High Molecular Weight Hyaluronan (HMWH)-induced Anti-hyperalgesia. J Pain. 2021 10; 22(10):1273-1282. Bonet IJM, Araldi D, Green PG, Levine JD. PMID: 33892155; PMCID: PMC8500912.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    7. Sexual dimorphism in the contribution of neuroendocrine stress axes to oxaliplatin-induced painful peripheral neuropathy. Pain. 2021 03 01; 162(3):907-918. Staurengo-Ferrari L, Green PG, Araldi D, Ferrari LF, Miaskowski C, Levine JD. PMID: 32947545; PMCID: PMC7886966.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    8. Involvement of TACAN, a Mechanotransducing Ion Channel, in Inflammatory But Not Neuropathic Hyperalgesia in the Rat. J Pain. 2021 05; 22(5):498-508. Bonet IJM, Araldi D, Bogen O, Levine JD. PMID: 33232830; PMCID: PMC8122021.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    9. Opioid-Induced Hyperalgesic Priming in Single Nociceptors. J Neurosci. 2021 01 06; 41(1):31-46. Khomula EV, Araldi D, Bonet IJM, Levine JD. PMID: 33203743; PMCID: PMC7786210.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    10. Mechanisms Mediating High-Molecular-Weight Hyaluronan-Induced Antihyperalgesia. J Neurosci. 2020 08 19; 40(34):6477-6488. Bonet IJM, Araldi D, Khomula EV, Bogen O, Green PG, Levine JD. PMID: 32665406; PMCID: PMC7486649.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    11. Peripheral Inflammatory Hyperalgesia Depends on P2X7 Receptors in Satellite Glial Cells. Front Physiol. 2020; 11:473. Neves AF, Farias FH, de Magalhães SF, Araldi D, Pagliusi M, Tambeli CH, Sartori CR, Lotufo CMDC, Parada CA. PMID: 32523543; PMCID: PMC7261868.
      View in: PubMed   Mentions: 8  
    12. Marked sexual dimorphism in neuroendocrine mechanisms for the exacerbation of paclitaxel-induced painful peripheral neuropathy by stress. Pain. 2020 04; 161(4):865-874. Ferrari LF, Araldi D, Green PG, Levine JD. PMID: 31917777; PMCID: PMC7085433.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    13. In Vitro Nociceptor Neuroplasticity Associated with In Vivo Opioid-Induced Hyperalgesia. J Neurosci. 2019 09 04; 39(36):7061-7073. Khomula EV, Araldi D, Levine JD. PMID: 31300521; PMCID: PMC6733538.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    14. Role of Nociceptor Toll-like Receptor 4 (TLR4) in Opioid-Induced Hyperalgesia and Hyperalgesic Priming. J Neurosci. 2019 08 14; 39(33):6414-6424. Araldi D, Bogen O, Green PG, Levine JD. PMID: 31209174; PMCID: PMC6697398.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    15. Systemic Morphine Produces Dose-dependent Nociceptor-mediated Biphasic Changes in Nociceptive Threshold and Neuroplasticity. Neuroscience. 2019 02 01; 398:64-75. Ferrari LF, Araldi D, Bogen O, Green PG, Levine JD. PMID: 30529265; PMCID: PMC9948647.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    16. Mu-opioid Receptor (MOR) Biased Agonists Induce Biphasic Dose-dependent Hyperalgesia and Analgesia, and Hyperalgesic Priming in the Rat. Neuroscience. 2018 12 01; 394:60-71. Araldi D, Ferrari LF, Levine JD. PMID: 30342200; PMCID: PMC6261666.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    17. Role of GPCR (mu-opioid)-receptor tyrosine kinase (epidermal growth factor) crosstalk in opioid-induced hyperalgesic priming (type II). Pain. 2018 May; 159(5):864-875. Araldi D, Ferrari LF, Levine JD. PMID: 29447132; PMCID: PMC5908744.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    18. Fentanyl Induces Rapid Onset Hyperalgesic Priming: Type I at Peripheral and Type II at Central Nociceptor Terminals. J Neurosci. 2018 02 28; 38(9):2226-2245. Araldi D, Khomula EV, Ferrari LF, Levine JD. PMID: 29431655; PMCID: PMC5830512.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    19. CD44 Signaling Mediates High Molecular Weight Hyaluronan-Induced Antihyperalgesia. J Neurosci. 2018 01 10; 38(2):308-321. Ferrari LF, Khomula EV, Araldi D, Levine JD. PMID: 29175954; PMCID: PMC5761612.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    20. Hyperalgesic priming (type II) induced by repeated opioid exposure: maintenance mechanisms. Pain. 2017 07; 158(7):1204-1216. Araldi D, Ferrari LF, Levine JD. PMID: 28306605; PMCID: PMC5474187.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    21. Age-Dependent Sexual Dimorphism in Susceptibility to Develop Chronic Pain in the Rat. Neuroscience. 2018 09 01; 387:170-177. Ferrari LF, Araldi D, Green P, Levine JD. PMID: 28676241; PMCID: PMC5748377.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    22. Antihyperalgesic effect of CB1 receptor activation involves the modulation of P2X3 receptor in the primary afferent neuron. Eur J Pharmacol. 2017 Mar 05; 798:113-121. Oliveira-Fusaro MCG, Zanoni CIS, Dos Santos GG, Manzo LP, Araldi D, Bonet IJM, Tambeli CH, Dias EV, Parada CA. PMID: 28131783.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    23. Sexual Dimorphism in a Reciprocal Interaction of Ryanodine and IP3 Receptors in the Induction of Hyperalgesic Priming. J Neurosci. 2017 02 22; 37(8):2032-2044. Khomula EV, Ferrari LF, Araldi D, Levine JD. PMID: 28115480; PMCID: PMC5338754.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    24. Regulation of Expression of Hyperalgesic Priming by Estrogen Receptor α in the Rat. J Pain. 2017 05; 18(5):574-582. Ferrari LF, Araldi D, Levine JD. PMID: 28089711; PMCID: PMC5429204.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    25. Marked sexual dimorphism in 5-HT1 receptors mediating pronociceptive effects of sumatriptan. Neuroscience. 2017 03 06; 344:394-405. Araldi D, Ferrari LF, Green P, Levine JD. PMID: 28040566; PMCID: PMC5321636.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    26. Janus kinase 2 activation participates in prostaglandin E2-induced hyperalgesia. Life Sci. 2016 Dec 01; 166:8-12. Vieira AS, Araldi D, Dias EV, do Prado FC, Tambeli CH, Parada CA. PMID: 27717845.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    27. Marked Sexual Dimorphism in the Role of the Ryanodine Receptor in a Model of Pain Chronification in the Rat. Sci Rep. 2016 08 08; 6:31221. Ferrari LF, Khomula EV, Araldi D, Levine JD. PMID: 27499186; PMCID: PMC4976309.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    28. Gi-protein-coupled 5-HT1B/D receptor agonist sumatriptan induces type I hyperalgesic priming. Pain. 2016 08; 157(8):1773-1782. Araldi D, Ferrari LF, Levine JD. PMID: 27075428; PMCID: PMC5048915.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    29. Extracellular matrix hyaluronan signals via its CD44 receptor in the increased responsiveness to mechanical stimulation. Neuroscience. 2016 Jun 02; 324:390-8. Ferrari LF, Araldi D, Bogen O, Levine JD. PMID: 26996509; PMCID: PMC5365238.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    30. Adenosine-A1 receptor agonist induced hyperalgesic priming type II. Pain. 2016 Mar; 157(3):698-709. Araldi D, Ferrari LF, Levine JD. PMID: 26588695; PMCID: PMC5048916.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    31. Repeated Mu-Opioid Exposure Induces a Novel Form of the Hyperalgesic Priming Model for Transition to Chronic Pain. J Neurosci. 2015 Sep 09; 35(36):12502-17. Araldi D, Ferrari LF, Levine JD. PMID: 26354917; PMCID: PMC4563038.
      View in: PubMed   Mentions: 39     Fields:    Translation:Animals
    32. Distinct terminal and cell body mechanisms in the nociceptor mediate hyperalgesic priming. J Neurosci. 2015 Apr 15; 35(15):6107-16. Ferrari LF, Araldi D, Levine JD. PMID: 25878283; PMCID: PMC4397607.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    33. Inflammatory sensitization of nociceptors depends on activation of NMDA receptors in DRG satellite cells. Proc Natl Acad Sci U S A. 2014 Dec 23; 111(51):18363-8. Ferrari LF, Lotufo CM, Araldi D, Rodrigues MA, Macedo LP, Ferreira SH, Parada CA. PMID: 25489099; PMCID: PMC4280647.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    34. P2X3 receptors induced inflammatory nociception modulated by TRPA1, 5-HT3 and 5-HT1A receptors. Pharmacol Biochem Behav. 2013 Nov; 112:49-55. Krimon S, Araldi D, do Prado FC, Tambeli CH, Oliveira-Fusaro MC, Parada CA. PMID: 24120766.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    35. Peripheral inflammatory hyperalgesia depends on the COX increase in the dorsal root ganglion. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3603-8. Araldi D, Ferrari LF, Lotufo CM, Vieira AS, Athié MC, Figueiredo JG, Duarte DB, Tambeli CH, Ferreira SH, Parada CA. PMID: 23401543; PMCID: PMC3587281.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    36. Neuronal P2X3 receptor activation is essential to the hyperalgesia induced by prostaglandins and sympathomimetic amines released during inflammation. Neuropharmacology. 2013 Apr; 67:252-8. Prado FC, Araldi D, Vieira AS, Oliveira-Fusaro MC, Tambeli CH, Parada CA. PMID: 23186588.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    37. Nanoassisted laser desorption-ionization-MS imaging of tumors. Anal Chem. 2012 Aug 07; 84(15):6341-5. Tata A, Fernandes AM, Santos VG, Alberici RM, Araldi D, Parada CA, Braguini W, Veronez L, Silva Bisson G, Reis FH, Alberici LC, Eberlin MN. PMID: 22741519.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    38. Inflammation-induced decrease in voluntary wheel running in mice: a nonreflexive test for evaluating inflammatory pain and analgesia. Pain. 2012 Apr; 153(4):876-884. Cobos EJ, Ghasemlou N, Araldi D, Segal D, Duong K, Woolf CJ. PMID: 22341563; PMCID: PMC3319437.
      View in: PubMed   Mentions: 111     Fields:    Translation:Animals
    39. P2X3 and P2X2/3 receptors mediate mechanical hyperalgesia induced by bradykinin, but not by pro-inflammatory cytokines, PGE₂ or dopamine. Eur J Pharmacol. 2010 Dec 15; 649(1-3):177-82. de Oliveira Fusaro MC, Pelegrini-da-Silva A, Araldi D, Parada CA, Tambeli CH. PMID: 20868656.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    40. Acute diphenyl diselenide treatment reduces hyperglycemia but does not change delta-aminolevulinate dehydratase activity in alloxan-induced diabetes in rats. Biol Pharm Bull. 2008 Dec; 31(12):2200-4. Barbosa NB, Oliveira C, Araldi D, Folmer V, Rocha JB, Nogueira CW. PMID: 19043199.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    41. On the mechanisms involved in antinociception induced by diphenyl diselenide. Environ Toxicol Pharmacol. 2005 Feb; 19(2):283-9. Zasso FB, Goncales CE, Jung EA, Araldi D, Zeni G, Rocha JB, Nogueira CW. PMID: 21783487.
      View in: PubMed   Mentions: 5     Fields:    
    42. Antinociceptive properties of acetylenic thiophene and furan derivatives: evidence for the mechanism of action. Life Sci. 2005 Mar 25; 76(19):2221-34. Goncales CE, Araldi D, Panatieri RB, Rocha JB, Zeni G, Nogueira CW. PMID: 15733937.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
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